Amino acid dipepetide frequency for Sanxia picorna-like virus 8

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.247AlaAla: 6.247 ± 0.0
0.416AlaCys: 0.416 ± 0.0
1.249AlaAsp: 1.249 ± 0.0
2.499AlaGlu: 2.499 ± 0.0
2.915AlaPhe: 2.915 ± 0.0
3.332AlaGly: 3.332 ± 0.0
1.666AlaHis: 1.666 ± 0.0
4.581AlaIle: 4.581 ± 0.0
2.499AlaLys: 2.499 ± 0.0
2.915AlaLeu: 2.915 ± 0.0
1.249AlaMet: 1.249 ± 0.0
4.581AlaAsn: 4.581 ± 0.0
2.915AlaPro: 2.915 ± 0.0
2.499AlaGln: 2.499 ± 0.0
1.666AlaArg: 1.666 ± 0.0
5.831AlaSer: 5.831 ± 0.0
3.332AlaThr: 3.332 ± 0.0
5.414AlaVal: 5.414 ± 0.0
1.666AlaTrp: 1.666 ± 0.0
3.748AlaTyr: 3.748 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.416CysAla: 0.416 ± 0.0
0.416CysCys: 0.416 ± 0.0
0.0CysAsp: 0.0 ± 0.0
1.249CysGlu: 1.249 ± 0.0
0.416CysPhe: 0.416 ± 0.0
2.082CysGly: 2.082 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.833CysIle: 0.833 ± 0.0
1.249CysLys: 1.249 ± 0.0
2.082CysLeu: 2.082 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.416CysAsn: 0.416 ± 0.0
1.249CysPro: 1.249 ± 0.0
0.416CysGln: 0.416 ± 0.0
1.249CysArg: 1.249 ± 0.0
0.416CysSer: 0.416 ± 0.0
0.416CysThr: 0.416 ± 0.0
2.082CysVal: 2.082 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.416CysTyr: 0.416 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.499AspAla: 2.499 ± 0.0
1.666AspCys: 1.666 ± 0.0
3.332AspAsp: 3.332 ± 0.0
2.915AspGlu: 2.915 ± 0.0
5.831AspPhe: 5.831 ± 0.0
4.581AspGly: 4.581 ± 0.0
1.666AspHis: 1.666 ± 0.0
2.915AspIle: 2.915 ± 0.0
2.082AspLys: 2.082 ± 0.0
4.581AspLeu: 4.581 ± 0.0
1.249AspMet: 1.249 ± 0.0
0.833AspAsn: 0.833 ± 0.0
2.915AspPro: 2.915 ± 0.0
0.416AspGln: 0.416 ± 0.0
1.666AspArg: 1.666 ± 0.0
4.581AspSer: 4.581 ± 0.0
4.165AspThr: 4.165 ± 0.0
4.998AspVal: 4.998 ± 0.0
0.416AspTrp: 0.416 ± 0.0
0.833AspTyr: 0.833 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
2.499GluAla: 2.499 ± 0.0
0.0GluCys: 0.0 ± 0.0
2.499GluAsp: 2.499 ± 0.0
2.915GluGlu: 2.915 ± 0.0
4.165GluPhe: 4.165 ± 0.0
1.666GluGly: 1.666 ± 0.0
1.666GluHis: 1.666 ± 0.0
4.581GluIle: 4.581 ± 0.0
4.998GluLys: 4.998 ± 0.0
6.247GluLeu: 6.247 ± 0.0
1.666GluMet: 1.666 ± 0.0
2.082GluAsn: 2.082 ± 0.0
2.915GluPro: 2.915 ± 0.0
1.666GluGln: 1.666 ± 0.0
2.499GluArg: 2.499 ± 0.0
3.332GluSer: 3.332 ± 0.0
2.082GluThr: 2.082 ± 0.0
5.831GluVal: 5.831 ± 0.0
1.249GluTrp: 1.249 ± 0.0
1.666GluTyr: 1.666 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
2.499PheAla: 2.499 ± 0.0
0.416PheCys: 0.416 ± 0.0
3.332PheAsp: 3.332 ± 0.0
4.165PheGlu: 4.165 ± 0.0
3.748PhePhe: 3.748 ± 0.0
3.748PheGly: 3.748 ± 0.0
2.082PheHis: 2.082 ± 0.0
4.165PheIle: 4.165 ± 0.0
2.915PheLys: 2.915 ± 0.0
6.247PheLeu: 6.247 ± 0.0
0.833PheMet: 0.833 ± 0.0
3.332PheAsn: 3.332 ± 0.0
2.082PhePro: 2.082 ± 0.0
1.666PheGln: 1.666 ± 0.0
2.915PheArg: 2.915 ± 0.0
1.666PheSer: 1.666 ± 0.0
4.165PheThr: 4.165 ± 0.0
4.165PheVal: 4.165 ± 0.0
1.249PheTrp: 1.249 ± 0.0
4.165PheTyr: 4.165 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
4.165GlyAla: 4.165 ± 0.0
0.0GlyCys: 0.0 ± 0.0
4.998GlyAsp: 4.998 ± 0.0
2.499GlyGlu: 2.499 ± 0.0
5.831GlyPhe: 5.831 ± 0.0
2.915GlyGly: 2.915 ± 0.0
0.833GlyHis: 0.833 ± 0.0
4.998GlyIle: 4.998 ± 0.0
3.748GlyLys: 3.748 ± 0.0
4.165GlyLeu: 4.165 ± 0.0
1.666GlyMet: 1.666 ± 0.0
2.915GlyAsn: 2.915 ± 0.0
3.748GlyPro: 3.748 ± 0.0
0.416GlyGln: 0.416 ± 0.0
2.915GlyArg: 2.915 ± 0.0
5.414GlySer: 5.414 ± 0.0
2.915GlyThr: 2.915 ± 0.0
3.748GlyVal: 3.748 ± 0.0
0.416GlyTrp: 0.416 ± 0.0
2.915GlyTyr: 2.915 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
0.833HisAla: 0.833 ± 0.0
1.249HisCys: 1.249 ± 0.0
2.082HisAsp: 2.082 ± 0.0
1.666HisGlu: 1.666 ± 0.0
2.082HisPhe: 2.082 ± 0.0
0.833HisGly: 0.833 ± 0.0
0.833HisHis: 0.833 ± 0.0
1.666HisIle: 1.666 ± 0.0
0.416HisLys: 0.416 ± 0.0
2.915HisLeu: 2.915 ± 0.0
0.833HisMet: 0.833 ± 0.0
1.666HisAsn: 1.666 ± 0.0
0.833HisPro: 0.833 ± 0.0
0.416HisGln: 0.416 ± 0.0
1.249HisArg: 1.249 ± 0.0
0.833HisSer: 0.833 ± 0.0
2.082HisThr: 2.082 ± 0.0
2.082HisVal: 2.082 ± 0.0
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.748IleAla: 3.748 ± 0.0
0.416IleCys: 0.416 ± 0.0
4.998IleAsp: 4.998 ± 0.0
4.998IleGlu: 4.998 ± 0.0
3.332IlePhe: 3.332 ± 0.0
2.082IleGly: 2.082 ± 0.0
1.666IleHis: 1.666 ± 0.0
2.915IleIle: 2.915 ± 0.0
4.998IleLys: 4.998 ± 0.0
4.165IleLeu: 4.165 ± 0.0
0.0IleMet: 0.0 ± 0.0
1.666IleAsn: 1.666 ± 0.0
4.165IlePro: 4.165 ± 0.0
2.499IleGln: 2.499 ± 0.0
2.082IleArg: 2.082 ± 0.0
8.746IleSer: 8.746 ± 0.0
3.332IleThr: 3.332 ± 0.0
2.915IleVal: 2.915 ± 0.0
0.0IleTrp: 0.0 ± 0.0
2.082IleTyr: 2.082 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
4.581LysAla: 4.581 ± 0.0
0.416LysCys: 0.416 ± 0.0
2.082LysAsp: 2.082 ± 0.0
4.165LysGlu: 4.165 ± 0.0
5.414LysPhe: 5.414 ± 0.0
0.833LysGly: 0.833 ± 0.0
0.833LysHis: 0.833 ± 0.0
4.998LysIle: 4.998 ± 0.0
4.998LysLys: 4.998 ± 0.0
4.165LysLeu: 4.165 ± 0.0
2.915LysMet: 2.915 ± 0.0
1.666LysAsn: 1.666 ± 0.0
1.666LysPro: 1.666 ± 0.0
2.499LysGln: 2.499 ± 0.0
3.332LysArg: 3.332 ± 0.0
4.998LysSer: 4.998 ± 0.0
3.748LysThr: 3.748 ± 0.0
1.249LysVal: 1.249 ± 0.0
0.416LysTrp: 0.416 ± 0.0
2.082LysTyr: 2.082 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
4.581LeuAla: 4.581 ± 0.0
2.499LeuCys: 2.499 ± 0.0
4.165LeuAsp: 4.165 ± 0.0
4.581LeuGlu: 4.581 ± 0.0
3.332LeuPhe: 3.332 ± 0.0
7.08LeuGly: 7.08 ± 0.0
3.332LeuHis: 3.332 ± 0.0
3.332LeuIle: 3.332 ± 0.0
5.414LeuLys: 5.414 ± 0.0
5.414LeuLeu: 5.414 ± 0.0
2.082LeuMet: 2.082 ± 0.0
4.165LeuAsn: 4.165 ± 0.0
1.666LeuPro: 1.666 ± 0.0
4.998LeuGln: 4.998 ± 0.0
4.165LeuArg: 4.165 ± 0.0
5.414LeuSer: 5.414 ± 0.0
7.913LeuThr: 7.913 ± 0.0
3.748LeuVal: 3.748 ± 0.0
0.833LeuTrp: 0.833 ± 0.0
1.666LeuTyr: 1.666 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
3.332MetAla: 3.332 ± 0.0
1.666MetCys: 1.666 ± 0.0
2.499MetAsp: 2.499 ± 0.0
1.666MetGlu: 1.666 ± 0.0
1.666MetPhe: 1.666 ± 0.0
1.666MetGly: 1.666 ± 0.0
1.666MetHis: 1.666 ± 0.0
1.249MetIle: 1.249 ± 0.0
1.249MetLys: 1.249 ± 0.0
2.499MetLeu: 2.499 ± 0.0
0.416MetMet: 0.416 ± 0.0
1.666MetAsn: 1.666 ± 0.0
0.416MetPro: 0.416 ± 0.0
1.249MetGln: 1.249 ± 0.0
1.249MetArg: 1.249 ± 0.0
1.249MetSer: 1.249 ± 0.0
0.833MetThr: 0.833 ± 0.0
0.833MetVal: 0.833 ± 0.0
0.833MetTrp: 0.833 ± 0.0
0.833MetTyr: 0.833 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.915AsnAla: 2.915 ± 0.0
1.249AsnCys: 1.249 ± 0.0
0.833AsnAsp: 0.833 ± 0.0
2.499AsnGlu: 2.499 ± 0.0
2.082AsnPhe: 2.082 ± 0.0
4.581AsnGly: 4.581 ± 0.0
0.416AsnHis: 0.416 ± 0.0
3.332AsnIle: 3.332 ± 0.0
2.082AsnLys: 2.082 ± 0.0
3.332AsnLeu: 3.332 ± 0.0
2.499AsnMet: 2.499 ± 0.0
3.332AsnAsn: 3.332 ± 0.0
2.915AsnPro: 2.915 ± 0.0
1.249AsnGln: 1.249 ± 0.0
1.666AsnArg: 1.666 ± 0.0
4.581AsnSer: 4.581 ± 0.0
3.332AsnThr: 3.332 ± 0.0
4.581AsnVal: 4.581 ± 0.0
0.833AsnTrp: 0.833 ± 0.0
1.666AsnTyr: 1.666 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
3.332ProAla: 3.332 ± 0.0
1.249ProCys: 1.249 ± 0.0
2.082ProAsp: 2.082 ± 0.0
2.499ProGlu: 2.499 ± 0.0
2.082ProPhe: 2.082 ± 0.0
2.082ProGly: 2.082 ± 0.0
2.082ProHis: 2.082 ± 0.0
1.666ProIle: 1.666 ± 0.0
1.666ProLys: 1.666 ± 0.0
2.915ProLeu: 2.915 ± 0.0
1.666ProMet: 1.666 ± 0.0
2.499ProAsn: 2.499 ± 0.0
0.833ProPro: 0.833 ± 0.0
1.249ProGln: 1.249 ± 0.0
0.833ProArg: 0.833 ± 0.0
4.165ProSer: 4.165 ± 0.0
4.581ProThr: 4.581 ± 0.0
3.748ProVal: 3.748 ± 0.0
1.249ProTrp: 1.249 ± 0.0
2.082ProTyr: 2.082 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
2.082GlnAla: 2.082 ± 0.0
0.0GlnCys: 0.0 ± 0.0
1.666GlnAsp: 1.666 ± 0.0
1.249GlnGlu: 1.249 ± 0.0
2.499GlnPhe: 2.499 ± 0.0
2.499GlnGly: 2.499 ± 0.0
0.0GlnHis: 0.0 ± 0.0
1.666GlnIle: 1.666 ± 0.0
1.666GlnLys: 1.666 ± 0.0
3.748GlnLeu: 3.748 ± 0.0
2.082GlnMet: 2.082 ± 0.0
1.666GlnAsn: 1.666 ± 0.0
1.249GlnPro: 1.249 ± 0.0
1.249GlnGln: 1.249 ± 0.0
1.249GlnArg: 1.249 ± 0.0
3.332GlnSer: 3.332 ± 0.0
2.082GlnThr: 2.082 ± 0.0
2.915GlnVal: 2.915 ± 0.0
0.416GlnTrp: 0.416 ± 0.0
1.666GlnTyr: 1.666 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
2.499ArgAla: 2.499 ± 0.0
0.416ArgCys: 0.416 ± 0.0
2.082ArgAsp: 2.082 ± 0.0
2.082ArgGlu: 2.082 ± 0.0
0.833ArgPhe: 0.833 ± 0.0
2.915ArgGly: 2.915 ± 0.0
0.416ArgHis: 0.416 ± 0.0
2.915ArgIle: 2.915 ± 0.0
1.666ArgLys: 1.666 ± 0.0
2.499ArgLeu: 2.499 ± 0.0
1.249ArgMet: 1.249 ± 0.0
2.915ArgAsn: 2.915 ± 0.0
2.499ArgPro: 2.499 ± 0.0
2.082ArgGln: 2.082 ± 0.0
2.499ArgArg: 2.499 ± 0.0
2.082ArgSer: 2.082 ± 0.0
3.748ArgThr: 3.748 ± 0.0
2.915ArgVal: 2.915 ± 0.0
0.416ArgTrp: 0.416 ± 0.0
1.249ArgTyr: 1.249 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
2.915SerAla: 2.915 ± 0.0
0.833SerCys: 0.833 ± 0.0
2.915SerAsp: 2.915 ± 0.0
7.497SerGlu: 7.497 ± 0.0
2.915SerPhe: 2.915 ± 0.0
2.915SerGly: 2.915 ± 0.0
1.666SerHis: 1.666 ± 0.0
4.165SerIle: 4.165 ± 0.0
5.831SerLys: 5.831 ± 0.0
6.247SerLeu: 6.247 ± 0.0
2.499SerMet: 2.499 ± 0.0
4.998SerAsn: 4.998 ± 0.0
2.499SerPro: 2.499 ± 0.0
3.332SerGln: 3.332 ± 0.0
2.082SerArg: 2.082 ± 0.0
4.998SerSer: 4.998 ± 0.0
8.746SerThr: 8.746 ± 0.0
4.165SerVal: 4.165 ± 0.0
1.249SerTrp: 1.249 ± 0.0
3.332SerTyr: 3.332 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
4.998ThrAla: 4.998 ± 0.0
0.416ThrCys: 0.416 ± 0.0
4.165ThrAsp: 4.165 ± 0.0
2.499ThrGlu: 2.499 ± 0.0
4.581ThrPhe: 4.581 ± 0.0
5.414ThrGly: 5.414 ± 0.0
0.833ThrHis: 0.833 ± 0.0
4.998ThrIle: 4.998 ± 0.0
1.666ThrLys: 1.666 ± 0.0
5.414ThrLeu: 5.414 ± 0.0
0.416ThrMet: 0.416 ± 0.0
3.748ThrAsn: 3.748 ± 0.0
4.581ThrPro: 4.581 ± 0.0
3.748ThrGln: 3.748 ± 0.0
2.082ThrArg: 2.082 ± 0.0
6.247ThrSer: 6.247 ± 0.0
6.664ThrThr: 6.664 ± 0.0
6.664ThrVal: 6.664 ± 0.0
0.416ThrTrp: 0.416 ± 0.0
2.499ThrTyr: 2.499 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
3.748ValAla: 3.748 ± 0.0
0.833ValCys: 0.833 ± 0.0
4.998ValAsp: 4.998 ± 0.0
2.499ValGlu: 2.499 ± 0.0
4.581ValPhe: 4.581 ± 0.0
4.581ValGly: 4.581 ± 0.0
1.249ValHis: 1.249 ± 0.0
3.748ValIle: 3.748 ± 0.0
4.581ValLys: 4.581 ± 0.0
4.581ValLeu: 4.581 ± 0.0
3.748ValMet: 3.748 ± 0.0
3.748ValAsn: 3.748 ± 0.0
4.165ValPro: 4.165 ± 0.0
2.915ValGln: 2.915 ± 0.0
3.332ValArg: 3.332 ± 0.0
3.748ValSer: 3.748 ± 0.0
2.915ValThr: 2.915 ± 0.0
2.915ValVal: 2.915 ± 0.0
0.833ValTrp: 0.833 ± 0.0
4.581ValTyr: 4.581 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.416TrpAla: 0.416 ± 0.0
0.416TrpCys: 0.416 ± 0.0
0.833TrpAsp: 0.833 ± 0.0
0.416TrpGlu: 0.416 ± 0.0
0.416TrpPhe: 0.416 ± 0.0
0.833TrpGly: 0.833 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
1.249TrpLys: 1.249 ± 0.0
1.666TrpLeu: 1.666 ± 0.0
0.416TrpMet: 0.416 ± 0.0
0.416TrpAsn: 0.416 ± 0.0
0.416TrpPro: 0.416 ± 0.0
0.0TrpGln: 0.0 ± 0.0
1.249TrpArg: 1.249 ± 0.0
1.249TrpSer: 1.249 ± 0.0
2.082TrpThr: 2.082 ± 0.0
0.833TrpVal: 0.833 ± 0.0
0.416TrpTrp: 0.416 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.332TyrAla: 3.332 ± 0.0
0.833TyrCys: 0.833 ± 0.0
3.332TyrAsp: 3.332 ± 0.0
1.666TyrGlu: 1.666 ± 0.0
0.833TyrPhe: 0.833 ± 0.0
4.581TyrGly: 4.581 ± 0.0
1.666TyrHis: 1.666 ± 0.0
2.082TyrIle: 2.082 ± 0.0
2.082TyrLys: 2.082 ± 0.0
4.581TyrLeu: 4.581 ± 0.0
0.833TyrMet: 0.833 ± 0.0
1.666TyrAsn: 1.666 ± 0.0
0.833TyrPro: 0.833 ± 0.0
0.416TyrGln: 0.416 ± 0.0
0.0TyrArg: 0.0 ± 0.0
2.915TyrSer: 2.915 ± 0.0
2.915TyrThr: 2.915 ± 0.0
2.499TyrVal: 2.499 ± 0.0
0.416TyrTrp: 0.416 ± 0.0
4.165TyrTyr: 4.165 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (2402 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski