Amino acid dipepetide frequency for Wuhan insect virus 33

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.724AlaAla: 4.724 ± 0.29
1.817AlaCys: 1.817 ± 0.889
2.907AlaAsp: 2.907 ± 1.179
2.18AlaGlu: 2.18 ± 0.884
2.544AlaPhe: 2.544 ± 0.594
3.634AlaGly: 3.634 ± 0.823
1.09AlaHis: 1.09 ± 0.533
4.36AlaIle: 4.36 ± 1.484
2.907AlaLys: 2.907 ± 0.122
5.814AlaLeu: 5.814 ± 0.894
1.817AlaMet: 1.817 ± 0.239
3.997AlaAsn: 3.997 ± 0.005
3.634AlaPro: 3.634 ± 0.173
4.724AlaGln: 4.724 ± 0.361
4.36AlaArg: 4.36 ± 2.418
5.087AlaSer: 5.087 ± 0.539
5.814AlaThr: 5.814 ± 2.357
1.817AlaVal: 1.817 ± 0.412
0.0AlaTrp: 0.0 ± 0.0
1.453AlaTyr: 1.453 ± 0.589
0.0AlaXaa: 0.0 ± 0.0
Cys
2.544CysAla: 2.544 ± 0.056
0.363CysCys: 0.363 ± 0.178
0.727CysAsp: 0.727 ± 0.356
0.363CysGlu: 0.363 ± 0.178
0.727CysPhe: 0.727 ± 0.356
1.817CysGly: 1.817 ± 0.412
0.727CysHis: 0.727 ± 0.356
1.817CysIle: 1.817 ± 0.889
2.18CysLys: 2.18 ± 1.067
2.544CysLeu: 2.544 ± 1.245
0.0CysMet: 0.0 ± 0.0
0.727CysAsn: 0.727 ± 0.295
1.09CysPro: 1.09 ± 0.533
0.363CysGln: 0.363 ± 0.178
1.09CysArg: 1.09 ± 0.533
1.09CysSer: 1.09 ± 0.533
0.363CysThr: 0.363 ± 0.178
3.27CysVal: 3.27 ± 0.95
0.363CysTrp: 0.363 ± 0.178
1.09CysTyr: 1.09 ± 0.533
0.0CysXaa: 0.0 ± 0.0
Asp
4.724AspAla: 4.724 ± 1.59
1.817AspCys: 1.817 ± 0.239
3.27AspAsp: 3.27 ± 0.3
2.18AspGlu: 2.18 ± 0.234
3.634AspPhe: 3.634 ± 0.478
4.36AspGly: 4.36 ± 0.183
0.0AspHis: 0.0 ± 0.0
3.634AspIle: 3.634 ± 0.173
3.27AspLys: 3.27 ± 1.6
5.451AspLeu: 5.451 ± 0.066
2.18AspMet: 2.18 ± 0.417
2.544AspAsn: 2.544 ± 1.245
1.817AspPro: 1.817 ± 0.889
1.817AspGln: 1.817 ± 0.889
1.817AspArg: 1.817 ± 0.889
3.997AspSer: 3.997 ± 1.306
5.087AspThr: 5.087 ± 2.063
4.724AspVal: 4.724 ± 0.29
0.363AspTrp: 0.363 ± 0.178
2.907AspTyr: 2.907 ± 0.122
0.0AspXaa: 0.0 ± 0.0
Glu
3.997GluAla: 3.997 ± 0.005
1.453GluCys: 1.453 ± 0.711
1.817GluAsp: 1.817 ± 1.062
1.817GluGlu: 1.817 ± 0.889
3.27GluPhe: 3.27 ± 1.001
2.907GluGly: 2.907 ± 0.122
1.453GluHis: 1.453 ± 0.061
3.634GluIle: 3.634 ± 0.478
2.544GluLys: 2.544 ± 0.706
5.087GluLeu: 5.087 ± 1.189
1.453GluMet: 1.453 ± 0.061
0.727GluAsn: 0.727 ± 0.356
3.27GluPro: 3.27 ± 0.351
2.544GluGln: 2.544 ± 0.056
3.997GluArg: 3.997 ± 0.655
2.18GluSer: 2.18 ± 0.417
2.544GluThr: 2.544 ± 1.245
4.36GluVal: 4.36 ± 0.467
0.363GluTrp: 0.363 ± 0.178
3.997GluTyr: 3.997 ± 1.956
0.0GluXaa: 0.0 ± 0.0
Phe
2.544PheAla: 2.544 ± 1.357
1.09PheCys: 1.09 ± 0.117
2.544PheAsp: 2.544 ± 0.594
4.36PheGlu: 4.36 ± 0.833
1.453PhePhe: 1.453 ± 0.589
1.817PheGly: 1.817 ± 0.239
1.453PheHis: 1.453 ± 1.89
5.451PheIle: 5.451 ± 2.017
3.634PheLys: 3.634 ± 0.173
5.087PheLeu: 5.087 ± 2.063
0.363PheMet: 0.363 ± 0.178
4.724PheAsn: 4.724 ± 2.241
1.817PhePro: 1.817 ± 0.412
0.363PheGln: 0.363 ± 0.472
2.18PheArg: 2.18 ± 0.884
3.27PheSer: 3.27 ± 0.3
1.09PheThr: 1.09 ± 0.533
3.997PheVal: 3.997 ± 1.296
0.363PheTrp: 0.363 ± 0.472
1.817PheTyr: 1.817 ± 0.239
0.0PheXaa: 0.0 ± 0.0
Gly
4.724GlyAla: 4.724 ± 0.94
0.727GlyCys: 0.727 ± 0.356
4.724GlyAsp: 4.724 ± 0.361
1.817GlyGlu: 1.817 ± 0.239
2.18GlyPhe: 2.18 ± 1.534
1.453GlyGly: 1.453 ± 1.24
0.363GlyHis: 0.363 ± 0.178
3.997GlyIle: 3.997 ± 0.005
3.997GlyLys: 3.997 ± 0.655
1.817GlyLeu: 1.817 ± 0.239
1.453GlyMet: 1.453 ± 0.589
3.27GlyAsn: 3.27 ± 1.001
1.817GlyPro: 1.817 ± 0.412
2.18GlyGln: 2.18 ± 0.234
2.18GlyArg: 2.18 ± 0.884
3.634GlySer: 3.634 ± 2.124
3.634GlyThr: 3.634 ± 2.124
3.997GlyVal: 3.997 ± 1.306
0.363GlyTrp: 0.363 ± 0.472
1.09GlyTyr: 1.09 ± 0.117
0.0GlyXaa: 0.0 ± 0.0
His
1.09HisAla: 1.09 ± 0.767
1.09HisCys: 1.09 ± 0.533
1.09HisAsp: 1.09 ± 0.117
0.727HisGlu: 0.727 ± 0.356
0.727HisPhe: 0.727 ± 0.356
0.727HisGly: 0.727 ± 0.295
0.727HisHis: 0.727 ± 0.356
1.817HisIle: 1.817 ± 0.239
0.727HisLys: 0.727 ± 0.356
1.453HisLeu: 1.453 ± 0.061
1.09HisMet: 1.09 ± 0.117
0.727HisAsn: 0.727 ± 0.295
0.363HisPro: 0.363 ± 0.178
0.363HisGln: 0.363 ± 0.472
0.727HisArg: 0.727 ± 0.356
1.453HisSer: 1.453 ± 0.589
1.453HisThr: 1.453 ± 0.589
0.727HisVal: 0.727 ± 0.356
0.0HisTrp: 0.0 ± 0.0
0.727HisTyr: 0.727 ± 0.356
0.0HisXaa: 0.0 ± 0.0
Ile
4.724IleAla: 4.724 ± 1.011
1.453IleCys: 1.453 ± 0.711
5.451IleAsp: 5.451 ± 0.066
2.907IleGlu: 2.907 ± 0.528
1.817IlePhe: 1.817 ± 0.239
2.907IleGly: 2.907 ± 0.528
1.09IleHis: 1.09 ± 0.533
2.544IleIle: 2.544 ± 0.594
4.724IleLys: 4.724 ± 0.29
5.087IleLeu: 5.087 ± 1.839
0.727IleMet: 0.727 ± 0.356
5.087IleAsn: 5.087 ± 0.539
5.087IlePro: 5.087 ± 1.189
2.907IleGln: 2.907 ± 0.122
3.27IleArg: 3.27 ± 1.6
2.907IleSer: 2.907 ± 1.423
3.634IleThr: 3.634 ± 0.173
4.36IleVal: 4.36 ± 1.484
0.363IleTrp: 0.363 ± 0.472
2.907IleTyr: 2.907 ± 0.772
0.0IleXaa: 0.0 ± 0.0
Lys
2.544LysAla: 2.544 ± 1.245
1.453LysCys: 1.453 ± 0.711
3.634LysAsp: 3.634 ± 1.778
3.634LysGlu: 3.634 ± 0.478
4.36LysPhe: 4.36 ± 1.118
2.907LysGly: 2.907 ± 0.772
1.09LysHis: 1.09 ± 0.533
3.634LysIle: 3.634 ± 0.478
2.907LysLys: 2.907 ± 1.423
5.451LysLeu: 5.451 ± 1.367
0.363LysMet: 0.363 ± 0.178
2.544LysAsn: 2.544 ± 0.056
2.18LysPro: 2.18 ± 1.534
1.817LysGln: 1.817 ± 0.412
3.27LysArg: 3.27 ± 0.3
3.27LysSer: 3.27 ± 0.95
3.27LysThr: 3.27 ± 0.351
1.817LysVal: 1.817 ± 0.889
1.09LysTrp: 1.09 ± 0.117
3.634LysTyr: 3.634 ± 1.778
0.0LysXaa: 0.0 ± 0.0
Leu
4.36LeuAla: 4.36 ± 0.833
2.544LeuCys: 2.544 ± 0.594
7.631LeuAsp: 7.631 ± 1.783
4.36LeuGlu: 4.36 ± 0.183
5.087LeuPhe: 5.087 ± 0.539
2.907LeuGly: 2.907 ± 0.528
2.544LeuHis: 2.544 ± 0.056
4.724LeuIle: 4.724 ± 1.011
5.087LeuLys: 5.087 ± 1.839
6.904LeuLeu: 6.904 ± 1.428
1.453LeuMet: 1.453 ± 0.061
5.814LeuAsn: 5.814 ± 0.244
4.36LeuPro: 4.36 ± 0.467
2.907LeuGln: 2.907 ± 0.528
4.36LeuArg: 4.36 ± 0.833
6.541LeuSer: 6.541 ± 0.6
7.267LeuThr: 7.267 ± 1.646
5.814LeuVal: 5.814 ± 1.057
1.817LeuTrp: 1.817 ± 0.239
3.634LeuTyr: 3.634 ± 0.823
0.0LeuXaa: 0.0 ± 0.0
Met
1.453MetAla: 1.453 ± 0.061
0.727MetCys: 0.727 ± 0.295
1.453MetAsp: 1.453 ± 0.711
3.27MetGlu: 3.27 ± 0.3
0.727MetPhe: 0.727 ± 0.356
0.727MetGly: 0.727 ± 0.295
0.363MetHis: 0.363 ± 0.178
1.453MetIle: 1.453 ± 0.589
1.09MetLys: 1.09 ± 0.533
1.817MetLeu: 1.817 ± 1.062
1.09MetMet: 1.09 ± 0.533
0.727MetAsn: 0.727 ± 0.356
1.453MetPro: 1.453 ± 0.061
1.09MetGln: 1.09 ± 0.117
1.817MetArg: 1.817 ± 0.889
2.907MetSer: 2.907 ± 0.122
1.817MetThr: 1.817 ± 0.412
1.09MetVal: 1.09 ± 0.533
0.363MetTrp: 0.363 ± 0.178
1.09MetTyr: 1.09 ± 0.117
0.0MetXaa: 0.0 ± 0.0
Asn
1.09AsnAla: 1.09 ± 1.417
0.727AsnCys: 0.727 ± 0.356
1.09AsnAsp: 1.09 ± 0.533
2.18AsnGlu: 2.18 ± 0.884
4.36AsnPhe: 4.36 ± 1.118
3.634AsnGly: 3.634 ± 0.173
1.09AsnHis: 1.09 ± 0.767
3.27AsnIle: 3.27 ± 0.3
5.087AsnLys: 5.087 ± 0.539
7.267AsnLeu: 7.267 ± 0.305
1.817AsnMet: 1.817 ± 0.239
1.09AsnAsn: 1.09 ± 0.117
2.907AsnPro: 2.907 ± 0.528
2.18AsnGln: 2.18 ± 0.234
1.817AsnArg: 1.817 ± 0.412
3.997AsnSer: 3.997 ± 0.655
4.36AsnThr: 4.36 ± 0.467
2.907AsnVal: 2.907 ± 0.122
1.09AsnTrp: 1.09 ± 0.533
2.544AsnTyr: 2.544 ± 0.706
0.0AsnXaa: 0.0 ± 0.0
Pro
2.544ProAla: 2.544 ± 0.594
0.363ProCys: 0.363 ± 0.178
1.453ProAsp: 1.453 ± 0.061
3.27ProGlu: 3.27 ± 0.95
5.087ProPhe: 5.087 ± 1.412
2.544ProGly: 2.544 ± 0.056
0.727ProHis: 0.727 ± 0.945
3.634ProIle: 3.634 ± 0.173
1.09ProLys: 1.09 ± 0.117
6.904ProLeu: 6.904 ± 1.174
1.09ProMet: 1.09 ± 0.767
3.27ProAsn: 3.27 ± 0.351
0.727ProPro: 0.727 ± 0.356
0.727ProGln: 0.727 ± 0.356
3.27ProArg: 3.27 ± 1.001
3.634ProSer: 3.634 ± 1.128
2.544ProThr: 2.544 ± 1.357
2.907ProVal: 2.907 ± 1.829
0.727ProTrp: 0.727 ± 0.945
1.453ProTyr: 1.453 ± 0.061
0.0ProXaa: 0.0 ± 0.0
Gln
1.453GlnAla: 1.453 ± 1.24
1.453GlnCys: 1.453 ± 0.711
1.453GlnAsp: 1.453 ± 0.061
2.544GlnGlu: 2.544 ± 0.056
0.727GlnPhe: 0.727 ± 0.356
1.09GlnGly: 1.09 ± 0.767
0.363GlnHis: 0.363 ± 0.178
2.544GlnIle: 2.544 ± 1.245
1.09GlnLys: 1.09 ± 0.533
4.36GlnLeu: 4.36 ± 0.467
2.907GlnMet: 2.907 ± 0.377
1.453GlnAsn: 1.453 ± 0.061
1.453GlnPro: 1.453 ± 1.24
2.544GlnGln: 2.544 ± 0.706
1.09GlnArg: 1.09 ± 0.533
3.27GlnSer: 3.27 ± 0.95
2.18GlnThr: 2.18 ± 0.234
3.27GlnVal: 3.27 ± 1.651
0.0GlnTrp: 0.0 ± 0.0
1.09GlnTyr: 1.09 ± 0.533
0.0GlnXaa: 0.0 ± 0.0
Arg
3.634ArgAla: 3.634 ± 0.823
0.727ArgCys: 0.727 ± 0.356
2.907ArgAsp: 2.907 ± 0.122
2.907ArgGlu: 2.907 ± 0.772
1.453ArgPhe: 1.453 ± 1.24
1.09ArgGly: 1.09 ± 1.417
0.363ArgHis: 0.363 ± 0.178
4.36ArgIle: 4.36 ± 0.833
2.544ArgLys: 2.544 ± 0.594
6.904ArgLeu: 6.904 ± 1.428
1.453ArgMet: 1.453 ± 0.711
4.36ArgAsn: 4.36 ± 1.484
2.544ArgPro: 2.544 ± 0.594
1.09ArgGln: 1.09 ± 0.117
2.18ArgArg: 2.18 ± 1.067
2.907ArgSer: 2.907 ± 0.122
4.36ArgThr: 4.36 ± 1.768
3.997ArgVal: 3.997 ± 0.005
0.727ArgTrp: 0.727 ± 0.356
1.453ArgTyr: 1.453 ± 0.589
0.0ArgXaa: 0.0 ± 0.0
Ser
3.634SerAla: 3.634 ± 0.478
0.727SerCys: 0.727 ± 0.356
5.087SerAsp: 5.087 ± 1.412
2.907SerGlu: 2.907 ± 1.423
4.36SerPhe: 4.36 ± 1.118
4.36SerGly: 4.36 ± 0.183
1.453SerHis: 1.453 ± 0.061
6.177SerIle: 6.177 ± 1.722
3.997SerLys: 3.997 ± 0.655
3.997SerLeu: 3.997 ± 0.655
1.817SerMet: 1.817 ± 0.994
2.18SerAsn: 2.18 ± 0.417
2.544SerPro: 2.544 ± 2.007
2.544SerGln: 2.544 ± 0.594
5.087SerArg: 5.087 ± 1.189
3.997SerSer: 3.997 ± 0.655
4.36SerThr: 4.36 ± 1.768
5.087SerVal: 5.087 ± 1.189
1.817SerTrp: 1.817 ± 1.712
2.18SerTyr: 2.18 ± 0.417
0.0SerXaa: 0.0 ± 0.0
Thr
5.451ThrAla: 5.451 ± 1.367
0.363ThrCys: 0.363 ± 0.178
3.634ThrAsp: 3.634 ± 0.823
6.177ThrGlu: 6.177 ± 0.422
2.544ThrPhe: 2.544 ± 1.357
4.36ThrGly: 4.36 ± 1.768
0.363ThrHis: 0.363 ± 0.472
2.907ThrIle: 2.907 ± 0.528
1.817ThrLys: 1.817 ± 0.412
6.177ThrLeu: 6.177 ± 1.072
1.453ThrMet: 1.453 ± 0.589
5.087ThrAsn: 5.087 ± 2.713
4.36ThrPro: 4.36 ± 1.768
2.544ThrGln: 2.544 ± 1.357
2.907ThrArg: 2.907 ± 0.122
4.36ThrSer: 4.36 ± 0.467
3.27ThrThr: 3.27 ± 1.651
4.724ThrVal: 4.724 ± 2.241
0.727ThrTrp: 0.727 ± 0.295
1.817ThrTyr: 1.817 ± 1.062
0.0ThrXaa: 0.0 ± 0.0
Val
5.087ValAla: 5.087 ± 0.762
2.544ValCys: 2.544 ± 0.056
4.724ValAsp: 4.724 ± 0.361
4.36ValGlu: 4.36 ± 0.467
2.18ValPhe: 2.18 ± 0.417
3.27ValGly: 3.27 ± 1.651
1.453ValHis: 1.453 ± 0.711
1.817ValIle: 1.817 ± 0.889
2.907ValLys: 2.907 ± 0.122
5.451ValLeu: 5.451 ± 1.235
1.817ValMet: 1.817 ± 0.239
3.997ValAsn: 3.997 ± 0.005
3.634ValPro: 3.634 ± 1.473
0.727ValGln: 0.727 ± 0.295
2.907ValArg: 2.907 ± 0.528
5.814ValSer: 5.814 ± 1.707
3.634ValThr: 3.634 ± 0.478
2.907ValVal: 2.907 ± 1.829
0.727ValTrp: 0.727 ± 0.356
4.724ValTyr: 4.724 ± 0.361
0.0ValXaa: 0.0 ± 0.0
Trp
0.363TrpAla: 0.363 ± 0.178
0.363TrpCys: 0.363 ± 0.178
0.727TrpAsp: 0.727 ± 0.356
0.0TrpGlu: 0.0 ± 0.0
1.817TrpPhe: 1.817 ± 0.412
1.09TrpGly: 1.09 ± 0.117
0.0TrpHis: 0.0 ± 0.0
0.727TrpIle: 0.727 ± 0.945
1.09TrpLys: 1.09 ± 0.117
0.363TrpLeu: 0.363 ± 0.472
0.727TrpMet: 0.727 ± 0.356
0.727TrpAsn: 0.727 ± 0.295
0.363TrpPro: 0.363 ± 0.472
0.727TrpGln: 0.727 ± 0.356
1.09TrpArg: 1.09 ± 0.117
0.363TrpSer: 0.363 ± 0.472
0.727TrpThr: 0.727 ± 0.295
0.363TrpVal: 0.363 ± 0.472
0.0TrpTrp: 0.0 ± 0.0
1.09TrpTyr: 1.09 ± 0.533
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.997TyrAla: 3.997 ± 0.005
1.453TyrCys: 1.453 ± 0.711
3.27TyrAsp: 3.27 ± 1.6
1.453TyrGlu: 1.453 ± 0.711
0.363TyrPhe: 0.363 ± 0.178
1.817TyrGly: 1.817 ± 0.239
1.09TyrHis: 1.09 ± 0.533
1.453TyrIle: 1.453 ± 0.711
2.18TyrLys: 2.18 ± 1.067
2.18TyrLeu: 2.18 ± 0.234
1.09TyrMet: 1.09 ± 0.767
1.453TyrAsn: 1.453 ± 0.589
2.544TyrPro: 2.544 ± 0.594
2.18TyrGln: 2.18 ± 1.067
2.544TyrArg: 2.544 ± 0.056
3.997TyrSer: 3.997 ± 1.296
3.634TyrThr: 3.634 ± 0.478
2.544TyrVal: 2.544 ± 1.357
1.453TyrTrp: 1.453 ± 0.061
4.724TyrTyr: 4.724 ± 0.94
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2753 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski