Amino acid dipepetide frequency for Gossypium australe

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.367AlaAla: 5.367 ± 0.034	1.199AlaCys: 1.199 ± 0.01	2.9AlaAsp: 2.9 ± 0.015	3.997AlaGlu: 3.997 ± 0.018	2.687AlaPhe: 2.687 ± 0.017	3.514AlaGly: 3.514 ± 0.02	1.222AlaHis: 1.222 ± 0.009	3.715AlaIle: 3.715 ± 0.018	3.892AlaLys: 3.892 ± 0.018	6.424AlaLeu: 6.424 ± 0.025	1.747AlaMet: 1.747 ± 0.011	2.652AlaAsn: 2.652 ± 0.014	2.828AlaPro: 2.828 ± 0.019	2.074AlaGln: 2.074 ± 0.013	3.282AlaArg: 3.282 ± 0.016	5.587AlaSer: 5.587 ± 0.023	3.468AlaThr: 3.468 ± 0.017	4.362AlaVal: 4.362 ± 0.019	0.775AlaTrp: 0.775 ± 0.007	1.978AlaTyr: 1.978 ± 0.013	0.0AlaXaa: 0.0 ± 0.0
Cys	0.896CysAla: 0.896 ± 0.008	0.52CysCys: 0.52 ± 0.008	0.864CysAsp: 0.864 ± 0.008	1.021CysGlu: 1.021 ± 0.01	0.971CysPhe: 0.971 ± 0.009	1.304CysGly: 1.304 ± 0.011	0.475CysHis: 0.475 ± 0.006	1.157CysIle: 1.157 ± 0.009	1.241CysLys: 1.241 ± 0.012	1.971CysLeu: 1.971 ± 0.013	0.487CysMet: 0.487 ± 0.006	0.878CysAsn: 0.878 ± 0.009	0.955CysPro: 0.955 ± 0.009	0.721CysGln: 0.721 ± 0.007	1.063CysArg: 1.063 ± 0.01	1.789CysSer: 1.789 ± 0.014	0.848CysThr: 0.848 ± 0.008	1.158CysVal: 1.158 ± 0.01	0.292CysTrp: 0.292 ± 0.005	0.569CysTyr: 0.569 ± 0.007	0.0CysXaa: 0.0 ± 0.0
Asp	3.258AspAla: 3.258 ± 0.016	1.04AspCys: 1.04 ± 0.008	3.455AspAsp: 3.455 ± 0.024	3.761AspGlu: 3.761 ± 0.021	2.374AspPhe: 2.374 ± 0.015	3.573AspGly: 3.573 ± 0.016	1.202AspHis: 1.202 ± 0.01	3.091AspIle: 3.091 ± 0.015	2.829AspLys: 2.829 ± 0.015	5.152AspLeu: 5.152 ± 0.025	1.406AspMet: 1.406 ± 0.011	2.153AspAsn: 2.153 ± 0.012	2.481AspPro: 2.481 ± 0.014	1.729AspGln: 1.729 ± 0.011	2.603AspArg: 2.603 ± 0.017	3.954AspSer: 3.954 ± 0.019	2.081AspThr: 2.081 ± 0.014	3.538AspVal: 3.538 ± 0.017	0.757AspTrp: 0.757 ± 0.008	1.621AspTyr: 1.621 ± 0.011	0.0AspXaa: 0.0 ± 0.0
Glu	4.729GluAla: 4.729 ± 0.026	0.966GluCys: 0.966 ± 0.009	3.785GluAsp: 3.785 ± 0.02	5.922GluGlu: 5.922 ± 0.05	2.835GluPhe: 2.835 ± 0.018	3.546GluGly: 3.546 ± 0.018	1.271GluHis: 1.271 ± 0.01	3.891GluIle: 3.891 ± 0.022	4.856GluLys: 4.856 ± 0.031	6.343GluLeu: 6.343 ± 0.031	1.738GluMet: 1.738 ± 0.012	3.115GluAsn: 3.115 ± 0.022	2.019GluPro: 2.019 ± 0.012	2.115GluGln: 2.115 ± 0.013	3.467GluArg: 3.467 ± 0.021	4.417GluSer: 4.417 ± 0.021	3.088GluThr: 3.088 ± 0.021	4.198GluVal: 4.198 ± 0.022	0.825GluTrp: 0.825 ± 0.007	1.687GluTyr: 1.687 ± 0.01	0.0GluXaa: 0.0 ± 0.0
Phe	2.503PheAla: 2.503 ± 0.015	0.928PheCys: 0.928 ± 0.008	2.428PheAsp: 2.428 ± 0.012	2.425PheGlu: 2.425 ± 0.013	2.04PhePhe: 2.04 ± 0.015	2.967PheGly: 2.967 ± 0.018	1.191PheHis: 1.191 ± 0.009	2.458PheIle: 2.458 ± 0.014	2.259PheLys: 2.259 ± 0.014	4.599PheLeu: 4.599 ± 0.022	1.083PheMet: 1.083 ± 0.01	1.831PheAsn: 1.831 ± 0.012	2.092PhePro: 2.092 ± 0.013	1.68PheGln: 1.68 ± 0.011	2.231PheArg: 2.231 ± 0.014	4.159PheSer: 4.159 ± 0.019	2.089PheThr: 2.089 ± 0.014	2.981PheVal: 2.981 ± 0.015	0.691PheTrp: 0.691 ± 0.007	1.295PheTyr: 1.295 ± 0.011	0.0PheXaa: 0.0 ± 0.0
Gly	3.573GlyAla: 3.573 ± 0.019	1.286GlyCys: 1.286 ± 0.011	3.172GlyAsp: 3.172 ± 0.018	3.452GlyGlu: 3.452 ± 0.018	3.166GlyPhe: 3.166 ± 0.019	4.527GlyGly: 4.527 ± 0.033	1.505GlyHis: 1.505 ± 0.012	3.636GlyIle: 3.636 ± 0.017	4.192GlyLys: 4.192 ± 0.019	5.848GlyLeu: 5.848 ± 0.023	1.496GlyMet: 1.496 ± 0.01	3.145GlyAsn: 3.145 ± 0.017	2.26GlyPro: 2.26 ± 0.013	2.019GlyGln: 2.019 ± 0.013	3.48GlyArg: 3.48 ± 0.019	5.686GlySer: 5.686 ± 0.024	3.162GlyThr: 3.162 ± 0.016	3.89GlyVal: 3.89 ± 0.018	0.864GlyTrp: 0.864 ± 0.008	2.055GlyTyr: 2.055 ± 0.015	0.0GlyXaa: 0.0 ± 0.0
His	1.263HisAla: 1.263 ± 0.01	0.545HisCys: 0.545 ± 0.006	1.143HisAsp: 1.143 ± 0.009	1.287HisGlu: 1.287 ± 0.01	1.146HisPhe: 1.146 ± 0.009	1.596HisGly: 1.596 ± 0.012	0.859HisHis: 0.859 ± 0.009	1.276HisIle: 1.276 ± 0.01	1.212HisLys: 1.212 ± 0.01	2.443HisLeu: 2.443 ± 0.015	0.537HisMet: 0.537 ± 0.007	0.972HisAsn: 0.972 ± 0.009	1.361HisPro: 1.361 ± 0.01	1.007HisGln: 1.007 ± 0.008	1.274HisArg: 1.274 ± 0.009	1.878HisSer: 1.878 ± 0.013	0.903HisThr: 0.903 ± 0.009	1.543HisVal: 1.543 ± 0.01	0.319HisTrp: 0.319 ± 0.005	0.767HisTyr: 0.767 ± 0.008	0.0HisXaa: 0.0 ± 0.0
Ile	3.574IleAla: 3.574 ± 0.017	1.225IleCys: 1.225 ± 0.009	3.234IleAsp: 3.234 ± 0.015	3.553IleGlu: 3.553 ± 0.021	2.431IlePhe: 2.431 ± 0.015	3.351IleGly: 3.351 ± 0.017	1.376IleHis: 1.376 ± 0.01	2.992IleIle: 2.992 ± 0.017	3.219IleLys: 3.219 ± 0.015	5.585IleLeu: 5.585 ± 0.022	1.246IleMet: 1.246 ± 0.011	2.374IleAsn: 2.374 ± 0.013	2.934IlePro: 2.934 ± 0.018	2.057IleGln: 2.057 ± 0.014	2.892IleArg: 2.892 ± 0.015	5.009IleSer: 5.009 ± 0.019	2.617IleThr: 2.617 ± 0.014	3.616IleVal: 3.616 ± 0.017	0.851IleTrp: 0.851 ± 0.01	1.557IleTyr: 1.557 ± 0.011	0.0IleXaa: 0.0 ± 0.0
Lys	4.271LysAla: 4.271 ± 0.019	1.222LysCys: 1.222 ± 0.011	3.425LysAsp: 3.425 ± 0.018	4.988LysGlu: 4.988 ± 0.034	2.334LysPhe: 2.334 ± 0.014	3.877LysGly: 3.877 ± 0.019	1.373LysHis: 1.373 ± 0.009	3.668LysIle: 3.668 ± 0.017	5.033LysLys: 5.033 ± 0.026	6.34LysLeu: 6.34 ± 0.025	1.605LysMet: 1.605 ± 0.012	2.798LysAsn: 2.798 ± 0.016	2.747LysPro: 2.747 ± 0.015	2.489LysGln: 2.489 ± 0.013	3.724LysArg: 3.724 ± 0.018	4.7LysSer: 4.7 ± 0.021	2.931LysThr: 2.931 ± 0.016	4.244LysVal: 4.244 ± 0.018	0.893LysTrp: 0.893 ± 0.009	1.852LysTyr: 1.852 ± 0.011	0.0LysXaa: 0.0 ± 0.0
Leu	6.249LeuAla: 6.249 ± 0.026	1.88LeuCys: 1.88 ± 0.012	4.966LeuAsp: 4.966 ± 0.02	6.34LeuGlu: 6.34 ± 0.031	4.075LeuPhe: 4.075 ± 0.02	5.843LeuGly: 5.843 ± 0.024	2.536LeuHis: 2.536 ± 0.014	4.943LeuIle: 4.943 ± 0.02	6.933LeuLys: 6.933 ± 0.026	9.803LeuLeu: 9.803 ± 0.043	2.371LeuMet: 2.371 ± 0.013	4.349LeuAsn: 4.349 ± 0.021	5.069LeuPro: 5.069 ± 0.024	4.409LeuGln: 4.409 ± 0.023	5.703LeuArg: 5.703 ± 0.022	8.48LeuSer: 8.48 ± 0.033	4.511LeuThr: 4.511 ± 0.02	6.557LeuVal: 6.557 ± 0.025	1.21LeuTrp: 1.21 ± 0.01	2.662LeuTyr: 2.662 ± 0.015	0.0LeuXaa: 0.0 ± 0.0
Met	2.126MetAla: 2.126 ± 0.012	0.39MetCys: 0.39 ± 0.005	1.541MetAsp: 1.541 ± 0.011	2.012MetGlu: 2.012 ± 0.013	0.889MetPhe: 0.889 ± 0.008	1.629MetGly: 1.629 ± 0.012	0.557MetHis: 0.557 ± 0.006	1.28MetIle: 1.28 ± 0.01	1.72MetLys: 1.72 ± 0.01	2.303MetLeu: 2.303 ± 0.014	0.715MetMet: 0.715 ± 0.007	1.158MetAsn: 1.158 ± 0.008	1.065MetPro: 1.065 ± 0.009	0.96MetGln: 0.96 ± 0.009	1.238MetArg: 1.238 ± 0.01	1.819MetSer: 1.819 ± 0.012	1.12MetThr: 1.12 ± 0.009	1.762MetVal: 1.762 ± 0.014	0.249MetTrp: 0.249 ± 0.004	0.607MetTyr: 0.607 ± 0.007	0.0MetXaa: 0.0 ± 0.0
Asn	2.638AsnAla: 2.638 ± 0.016	0.893AsnCys: 0.893 ± 0.01	2.137AsnAsp: 2.137 ± 0.014	2.712AsnGlu: 2.712 ± 0.019	2.03AsnPhe: 2.03 ± 0.014	3.361AsnGly: 3.361 ± 0.015	1.098AsnHis: 1.098 ± 0.009	2.566AsnIle: 2.566 ± 0.014	2.715AsnLys: 2.715 ± 0.014	4.717AsnLeu: 4.717 ± 0.026	1.188AsnMet: 1.188 ± 0.01	2.397AsnAsn: 2.397 ± 0.018	2.333AsnPro: 2.333 ± 0.013	1.756AsnGln: 1.756 ± 0.012	2.131AsnArg: 2.131 ± 0.012	3.748AsnSer: 3.748 ± 0.017	2.056AsnThr: 2.056 ± 0.014	2.927AsnVal: 2.927 ± 0.015	0.633AsnTrp: 0.633 ± 0.006	1.371AsnTyr: 1.371 ± 0.011	0.0AsnXaa: 0.0 ± 0.0
Pro	2.656ProAla: 2.656 ± 0.017	0.735ProCys: 0.735 ± 0.008	2.263ProAsp: 2.263 ± 0.014	2.963ProGlu: 2.963 ± 0.017	2.087ProPhe: 2.087 ± 0.013	2.594ProGly: 2.594 ± 0.016	1.045ProHis: 1.045 ± 0.008	2.453ProIle: 2.453 ± 0.014	2.831ProLys: 2.831 ± 0.014	4.37ProLeu: 4.37 ± 0.017	1.007ProMet: 1.007 ± 0.009	2.244ProAsn: 2.244 ± 0.013	3.458ProPro: 3.458 ± 0.048	1.73ProGln: 1.73 ± 0.015	2.373ProArg: 2.373 ± 0.012	4.778ProSer: 4.778 ± 0.021	2.588ProThr: 2.588 ± 0.015	3.043ProVal: 3.043 ± 0.018	0.649ProTrp: 0.649 ± 0.007	1.454ProTyr: 1.454 ± 0.011	0.0ProXaa: 0.0 ± 0.0
Gln	2.337GlnAla: 2.337 ± 0.014	0.646GlnCys: 0.646 ± 0.007	1.601GlnAsp: 1.601 ± 0.01	2.365GlnGlu: 2.365 ± 0.014	1.431GlnPhe: 1.431 ± 0.009	2.133GlnGly: 2.133 ± 0.012	0.934GlnHis: 0.934 ± 0.007	2.11GlnIle: 2.11 ± 0.014	2.456GlnLys: 2.456 ± 0.014	3.842GlnLeu: 3.842 ± 0.02	1.009GlnMet: 1.009 ± 0.009	1.793GlnAsn: 1.793 ± 0.011	1.796GlnPro: 1.796 ± 0.014	2.068GlnGln: 2.068 ± 0.026	2.148GlnArg: 2.148 ± 0.013	2.843GlnSer: 2.843 ± 0.018	1.671GlnThr: 1.671 ± 0.011	2.415GlnVal: 2.415 ± 0.013	0.508GlnTrp: 0.508 ± 0.007	0.963GlnTyr: 0.963 ± 0.008	0.0GlnXaa: 0.0 ± 0.0
Arg	3.15ArgAla: 3.15 ± 0.015	1.076ArgCys: 1.076 ± 0.009	2.737ArgAsp: 2.737 ± 0.017	3.395ArgGlu: 3.395 ± 0.022	2.469ArgPhe: 2.469 ± 0.014	3.197ArgGly: 3.197 ± 0.02	1.237ArgHis: 1.237 ± 0.009	3.068ArgIle: 3.068 ± 0.017	4.025ArgLys: 4.025 ± 0.02	5.158ArgLeu: 5.158 ± 0.019	1.422ArgMet: 1.422 ± 0.01	2.505ArgAsn: 2.505 ± 0.012	2.275ArgPro: 2.275 ± 0.015	1.997ArgGln: 1.997 ± 0.013	3.734ArgArg: 3.734 ± 0.021	4.24ArgSer: 4.24 ± 0.023	2.465ArgThr: 2.465 ± 0.013	3.458ArgVal: 3.458 ± 0.018	0.753ArgTrp: 0.753 ± 0.007	1.528ArgTyr: 1.528 ± 0.01	0.0ArgXaa: 0.0 ± 0.0
Ser	4.855SerAla: 4.855 ± 0.022	1.65SerCys: 1.65 ± 0.014	4.243SerAsp: 4.243 ± 0.02	4.656SerGlu: 4.656 ± 0.022	4.07SerPhe: 4.07 ± 0.019	5.562SerGly: 5.562 ± 0.023	1.906SerHis: 1.906 ± 0.013	4.703SerIle: 4.703 ± 0.017	5.226SerLys: 5.226 ± 0.022	8.539SerLeu: 8.539 ± 0.034	2.166SerMet: 2.166 ± 0.014	4.083SerAsn: 4.083 ± 0.018	4.23SerPro: 4.23 ± 0.025	2.936SerGln: 2.936 ± 0.017	4.38SerArg: 4.38 ± 0.021	10.017SerSer: 10.017 ± 0.049	4.57SerThr: 4.57 ± 0.021	5.017SerVal: 5.017 ± 0.018	1.146SerTrp: 1.146 ± 0.01	2.378SerTyr: 2.378 ± 0.013	0.0SerXaa: 0.0 ± 0.0
Thr	3.166ThrAla: 3.166 ± 0.018	0.892ThrCys: 0.892 ± 0.01	2.258ThrAsp: 2.258 ± 0.013	2.888ThrGlu: 2.888 ± 0.018	2.082ThrPhe: 2.082 ± 0.012	3.042ThrGly: 3.042 ± 0.016	1.033ThrHis: 1.033 ± 0.009	2.787ThrIle: 2.787 ± 0.015	2.945ThrLys: 2.945 ± 0.016	4.58ThrLeu: 4.58 ± 0.018	1.262ThrMet: 1.262 ± 0.01	2.156ThrAsn: 2.156 ± 0.013	2.451ThrPro: 2.451 ± 0.016	1.541ThrGln: 1.541 ± 0.011	2.392ThrArg: 2.392 ± 0.015	4.35ThrSer: 4.35 ± 0.022	2.845ThrThr: 2.845 ± 0.017	3.262ThrVal: 3.262 ± 0.015	0.721ThrTrp: 0.721 ± 0.009	1.372ThrTyr: 1.372 ± 0.011	0.0ThrXaa: 0.0 ± 0.0
Val	4.548ValAla: 4.548 ± 0.017	1.192ValCys: 1.192 ± 0.009	3.68ValAsp: 3.68 ± 0.016	4.433ValGlu: 4.433 ± 0.023	2.919ValPhe: 2.919 ± 0.016	3.945ValGly: 3.945 ± 0.02	1.402ValHis: 1.402 ± 0.009	3.628ValIle: 3.628 ± 0.017	4.178ValLys: 4.178 ± 0.021	6.506ValLeu: 6.506 ± 0.022	1.566ValMet: 1.566 ± 0.011	2.734ValAsn: 2.734 ± 0.016	3.189ValPro: 3.189 ± 0.016	2.251ValGln: 2.251 ± 0.014	3.187ValArg: 3.187 ± 0.015	5.528ValSer: 5.528 ± 0.022	3.138ValThr: 3.138 ± 0.017	4.929ValVal: 4.929 ± 0.021	0.794ValTrp: 0.794 ± 0.007	1.869ValTyr: 1.869 ± 0.012	0.0ValXaa: 0.0 ± 0.0
Trp	0.717TrpAla: 0.717 ± 0.008	0.254TrpCys: 0.254 ± 0.004	0.725TrpAsp: 0.725 ± 0.007	0.893TrpGlu: 0.893 ± 0.009	0.562TrpPhe: 0.562 ± 0.006	0.759TrpGly: 0.759 ± 0.008	0.329TrpHis: 0.329 ± 0.005	0.758TrpIle: 0.758 ± 0.007	1.152TrpLys: 1.152 ± 0.009	1.414TrpLeu: 1.414 ± 0.01	0.349TrpMet: 0.349 ± 0.005	0.744TrpAsn: 0.744 ± 0.007	0.479TrpPro: 0.479 ± 0.005	0.475TrpGln: 0.475 ± 0.006	0.945TrpArg: 0.945 ± 0.01	0.998TrpSer: 0.998 ± 0.008	0.625TrpThr: 0.625 ± 0.007	0.878TrpVal: 0.878 ± 0.009	0.331TrpTrp: 0.331 ± 0.006	0.365TrpTyr: 0.365 ± 0.006	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.791TyrAla: 1.791 ± 0.011	0.641TyrCys: 0.641 ± 0.007	1.502TyrAsp: 1.502 ± 0.012	1.75TyrGlu: 1.75 ± 0.011	1.331TyrPhe: 1.331 ± 0.011	2.096TyrGly: 2.096 ± 0.014	0.778TyrHis: 0.778 ± 0.008	1.516TyrIle: 1.516 ± 0.012	1.602TyrLys: 1.602 ± 0.01	2.951TyrLeu: 2.951 ± 0.017	0.74TyrMet: 0.74 ± 0.007	1.327TyrAsn: 1.327 ± 0.009	1.297TyrPro: 1.297 ± 0.01	1.055TyrGln: 1.055 ± 0.01	1.641TyrArg: 1.641 ± 0.011	2.353TyrSer: 2.353 ± 0.014	1.248TyrThr: 1.248 ± 0.01	1.838TyrVal: 1.838 ± 0.013	0.492TyrTrp: 0.492 ± 0.005	1.006TyrTyr: 1.006 ± 0.009	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 38125 proteins (14614465 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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