Amino acid dipepetide frequency for Sporosarcina newyorkensis 2681

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.575AlaAla: 6.575 ± 0.113	0.626AlaCys: 0.626 ± 0.025	3.982AlaAsp: 3.982 ± 0.06	5.355AlaGlu: 5.355 ± 0.088	3.447AlaPhe: 3.447 ± 0.068	5.743AlaGly: 5.743 ± 0.078	1.316AlaHis: 1.316 ± 0.038	6.152AlaIle: 6.152 ± 0.079	4.632AlaLys: 4.632 ± 0.077	7.464AlaLeu: 7.464 ± 0.088	2.29AlaMet: 2.29 ± 0.051	2.839AlaAsn: 2.839 ± 0.059	2.233AlaPro: 2.233 ± 0.049	2.475AlaGln: 2.475 ± 0.053	2.894AlaArg: 2.894 ± 0.057	4.356AlaSer: 4.356 ± 0.069	4.039AlaThr: 4.039 ± 0.066	6.034AlaVal: 6.034 ± 0.092	0.573AlaTrp: 0.573 ± 0.027	2.362AlaTyr: 2.362 ± 0.049	0.0AlaXaa: 0.0 ± 0.0
Cys	0.465CysAla: 0.465 ± 0.023	0.081CysCys: 0.081 ± 0.01	0.38CysAsp: 0.38 ± 0.018	0.449CysGlu: 0.449 ± 0.023	0.248CysPhe: 0.248 ± 0.017	0.672CysGly: 0.672 ± 0.025	0.191CysHis: 0.191 ± 0.013	0.508CysIle: 0.508 ± 0.024	0.372CysLys: 0.372 ± 0.021	0.624CysLeu: 0.624 ± 0.026	0.182CysMet: 0.182 ± 0.013	0.251CysAsn: 0.251 ± 0.015	0.357CysPro: 0.357 ± 0.021	0.226CysGln: 0.226 ± 0.018	0.29CysArg: 0.29 ± 0.018	0.498CysSer: 0.498 ± 0.024	0.399CysThr: 0.399 ± 0.018	0.415CysVal: 0.415 ± 0.021	0.07CysTrp: 0.07 ± 0.009	0.213CysTyr: 0.213 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	3.709AspAla: 3.709 ± 0.07	0.366AspCys: 0.366 ± 0.019	2.494AspAsp: 2.494 ± 0.049	4.775AspGlu: 4.775 ± 0.071	2.342AspPhe: 2.342 ± 0.051	3.535AspGly: 3.535 ± 0.065	1.17AspHis: 1.17 ± 0.034	3.9AspIle: 3.9 ± 0.072	2.854AspLys: 2.854 ± 0.057	5.014AspLeu: 5.014 ± 0.075	1.449AspMet: 1.449 ± 0.04	1.638AspAsn: 1.638 ± 0.044	2.031AspPro: 2.031 ± 0.045	2.174AspGln: 2.174 ± 0.045	2.527AspArg: 2.527 ± 0.054	2.687AspSer: 2.687 ± 0.059	2.535AspThr: 2.535 ± 0.049	3.957AspVal: 3.957 ± 0.076	0.661AspTrp: 0.661 ± 0.026	1.997AspTyr: 1.997 ± 0.044	0.0AspXaa: 0.0 ± 0.0
Glu	5.643GluAla: 5.643 ± 0.09	0.389GluCys: 0.389 ± 0.021	4.069GluAsp: 4.069 ± 0.07	7.125GluGlu: 7.125 ± 0.092	2.536GluPhe: 2.536 ± 0.059	4.522GluGly: 4.522 ± 0.067	1.53GluHis: 1.53 ± 0.043	5.347GluIle: 5.347 ± 0.081	5.928GluLys: 5.928 ± 0.085	7.442GluLeu: 7.442 ± 0.098	2.578GluMet: 2.578 ± 0.051	3.149GluAsn: 3.149 ± 0.064	2.132GluPro: 2.132 ± 0.05	3.931GluGln: 3.931 ± 0.075	3.962GluArg: 3.962 ± 0.066	3.573GluSer: 3.573 ± 0.069	4.09GluThr: 4.09 ± 0.067	5.395GluVal: 5.395 ± 0.081	0.81GluTrp: 0.81 ± 0.028	2.025GluTyr: 2.025 ± 0.045	0.0GluXaa: 0.0 ± 0.0
Phe	3.176PheAla: 3.176 ± 0.06	0.359PheCys: 0.359 ± 0.023	2.399PheAsp: 2.399 ± 0.048	2.95PheGlu: 2.95 ± 0.053	2.408PhePhe: 2.408 ± 0.055	3.377PheGly: 3.377 ± 0.071	0.974PheHis: 0.974 ± 0.033	3.785PheIle: 3.785 ± 0.062	2.255PheLys: 2.255 ± 0.047	4.406PheLeu: 4.406 ± 0.077	1.245PheMet: 1.245 ± 0.035	1.711PheAsn: 1.711 ± 0.035	1.625PhePro: 1.625 ± 0.04	1.48PheGln: 1.48 ± 0.033	1.619PheArg: 1.619 ± 0.042	3.227PheSer: 3.227 ± 0.065	2.677PheThr: 2.677 ± 0.055	3.119PheVal: 3.119 ± 0.059	0.456PheTrp: 0.456 ± 0.027	1.637PheTyr: 1.637 ± 0.037	0.0PheXaa: 0.0 ± 0.0
Gly	5.176GlyAla: 5.176 ± 0.083	0.555GlyCys: 0.555 ± 0.027	3.306GlyAsp: 3.306 ± 0.057	4.653GlyGlu: 4.653 ± 0.075	3.357GlyPhe: 3.357 ± 0.062	4.907GlyGly: 4.907 ± 0.08	1.353GlyHis: 1.353 ± 0.039	5.631GlyIle: 5.631 ± 0.083	4.9GlyLys: 4.9 ± 0.064	6.566GlyLeu: 6.566 ± 0.099	2.343GlyMet: 2.343 ± 0.053	2.615GlyAsn: 2.615 ± 0.055	1.78GlyPro: 1.78 ± 0.042	2.333GlyGln: 2.333 ± 0.055	2.869GlyArg: 2.869 ± 0.053	4.015GlySer: 4.015 ± 0.062	4.022GlyThr: 4.022 ± 0.067	5.277GlyVal: 5.277 ± 0.083	0.834GlyTrp: 0.834 ± 0.03	2.593GlyTyr: 2.593 ± 0.049	0.0GlyXaa: 0.0 ± 0.0
His	1.493HisAla: 1.493 ± 0.041	0.186HisCys: 0.186 ± 0.012	1.039HisAsp: 1.039 ± 0.033	1.432HisGlu: 1.432 ± 0.04	1.057HisPhe: 1.057 ± 0.036	1.402HisGly: 1.402 ± 0.041	0.58HisHis: 0.58 ± 0.024	1.388HisIle: 1.388 ± 0.042	0.938HisLys: 0.938 ± 0.03	2.078HisLeu: 2.078 ± 0.047	0.553HisMet: 0.553 ± 0.025	0.687HisAsn: 0.687 ± 0.025	1.171HisPro: 1.171 ± 0.039	0.79HisGln: 0.79 ± 0.027	0.893HisArg: 0.893 ± 0.035	1.226HisSer: 1.226 ± 0.037	1.074HisThr: 1.074 ± 0.034	1.399HisVal: 1.399 ± 0.038	0.226HisTrp: 0.226 ± 0.017	0.855HisTyr: 0.855 ± 0.036	0.0HisXaa: 0.0 ± 0.0
Ile	6.376IleAla: 6.376 ± 0.092	0.55IleCys: 0.55 ± 0.022	4.144IleAsp: 4.144 ± 0.075	5.63IleGlu: 5.63 ± 0.085	3.002IlePhe: 3.002 ± 0.07	6.173IleGly: 6.173 ± 0.09	1.716IleHis: 1.716 ± 0.043	5.378IleIle: 5.378 ± 0.101	3.672IleLys: 3.672 ± 0.065	6.744IleLeu: 6.744 ± 0.099	1.858IleMet: 1.858 ± 0.045	2.722IleAsn: 2.722 ± 0.057	3.19IlePro: 3.19 ± 0.057	3.007IleGln: 3.007 ± 0.055	3.36IleArg: 3.36 ± 0.064	4.661IleSer: 4.661 ± 0.074	4.086IleThr: 4.086 ± 0.059	5.658IleVal: 5.658 ± 0.089	0.678IleTrp: 0.678 ± 0.028	2.15IleTyr: 2.15 ± 0.05	0.0IleXaa: 0.0 ± 0.0
Lys	4.335LysAla: 4.335 ± 0.068	0.304LysCys: 0.304 ± 0.02	3.499LysAsp: 3.499 ± 0.067	6.165LysGlu: 6.165 ± 0.077	1.972LysPhe: 1.972 ± 0.041	4.131LysGly: 4.131 ± 0.057	1.171LysHis: 1.171 ± 0.034	4.026LysIle: 4.026 ± 0.06	5.202LysLys: 5.202 ± 0.093	5.446LysLeu: 5.446 ± 0.074	2.245LysMet: 2.245 ± 0.049	2.751LysAsn: 2.751 ± 0.056	2.191LysPro: 2.191 ± 0.051	2.858LysGln: 2.858 ± 0.051	3.335LysArg: 3.335 ± 0.061	3.447LysSer: 3.447 ± 0.068	3.515LysThr: 3.515 ± 0.057	4.398LysVal: 4.398 ± 0.061	0.765LysTrp: 0.765 ± 0.033	1.821LysTyr: 1.821 ± 0.049	0.0LysXaa: 0.0 ± 0.0
Leu	7.914LeuAla: 7.914 ± 0.11	0.613LeuCys: 0.613 ± 0.026	4.943LeuAsp: 4.943 ± 0.078	6.53LeuGlu: 6.53 ± 0.086	4.913LeuPhe: 4.913 ± 0.08	6.213LeuGly: 6.213 ± 0.084	2.068LeuHis: 2.068 ± 0.048	6.935LeuIle: 6.935 ± 0.095	5.731LeuLys: 5.731 ± 0.083	10.548LeuLeu: 10.548 ± 0.148	2.58LeuMet: 2.58 ± 0.056	3.782LeuAsn: 3.782 ± 0.059	4.057LeuPro: 4.057 ± 0.061	4.093LeuGln: 4.093 ± 0.075	3.985LeuArg: 3.985 ± 0.066	6.504LeuSer: 6.504 ± 0.079	6.003LeuThr: 6.003 ± 0.079	6.445LeuVal: 6.445 ± 0.091	0.75LeuTrp: 0.75 ± 0.027	3.037LeuTyr: 3.037 ± 0.049	0.0LeuXaa: 0.0 ± 0.0
Met	2.225MetAla: 2.225 ± 0.045	0.165MetCys: 0.165 ± 0.014	1.621MetAsp: 1.621 ± 0.039	2.202MetGlu: 2.202 ± 0.046	1.068MetPhe: 1.068 ± 0.036	1.904MetGly: 1.904 ± 0.047	0.491MetHis: 0.491 ± 0.023	2.114MetIle: 2.114 ± 0.049	2.775MetLys: 2.775 ± 0.061	2.67MetLeu: 2.67 ± 0.054	1.013MetMet: 1.013 ± 0.035	1.653MetAsn: 1.653 ± 0.038	1.122MetPro: 1.122 ± 0.036	1.115MetGln: 1.115 ± 0.033	1.307MetArg: 1.307 ± 0.034	1.748MetSer: 1.748 ± 0.043	1.933MetThr: 1.933 ± 0.039	1.767MetVal: 1.767 ± 0.04	0.22MetTrp: 0.22 ± 0.015	0.786MetTyr: 0.786 ± 0.024	0.0MetXaa: 0.0 ± 0.0
Asn	2.668AsnAla: 2.668 ± 0.052	0.295AsnCys: 0.295 ± 0.019	1.909AsnAsp: 1.909 ± 0.043	3.536AsnGlu: 3.536 ± 0.077	1.581AsnPhe: 1.581 ± 0.037	2.974AsnGly: 2.974 ± 0.055	0.861AsnHis: 0.861 ± 0.032	2.822AsnIle: 2.822 ± 0.053	2.388AsnLys: 2.388 ± 0.05	3.413AsnLeu: 3.413 ± 0.059	1.209AsnMet: 1.209 ± 0.035	1.561AsnAsn: 1.561 ± 0.045	2.013AsnPro: 2.013 ± 0.049	1.674AsnGln: 1.674 ± 0.039	1.925AsnArg: 1.925 ± 0.041	2.179AsnSer: 2.179 ± 0.049	1.978AsnThr: 1.978 ± 0.045	2.67AsnVal: 2.67 ± 0.049	0.499AsnTrp: 0.499 ± 0.024	1.37AsnTyr: 1.37 ± 0.044	0.0AsnXaa: 0.0 ± 0.0
Pro	2.702ProAla: 2.702 ± 0.06	0.245ProCys: 0.245 ± 0.016	2.062ProAsp: 2.062 ± 0.043	2.992ProGlu: 2.992 ± 0.057	1.962ProPhe: 1.962 ± 0.043	2.341ProGly: 2.341 ± 0.062	0.797ProHis: 0.797 ± 0.025	2.985ProIle: 2.985 ± 0.059	2.114ProLys: 2.114 ± 0.045	3.602ProLeu: 3.602 ± 0.055	0.942ProMet: 0.942 ± 0.032	1.515ProAsn: 1.515 ± 0.039	1.1ProPro: 1.1 ± 0.035	1.132ProGln: 1.132 ± 0.037	1.159ProArg: 1.159 ± 0.039	2.361ProSer: 2.361 ± 0.051	2.007ProThr: 2.007 ± 0.046	2.971ProVal: 2.971 ± 0.056	0.322ProTrp: 0.322 ± 0.019	1.354ProTyr: 1.354 ± 0.035	0.0ProXaa: 0.0 ± 0.0
Gln	3.104GlnAla: 3.104 ± 0.065	0.19GlnCys: 0.19 ± 0.015	1.751GlnAsp: 1.751 ± 0.037	2.847GlnGlu: 2.847 ± 0.054	1.734GlnPhe: 1.734 ± 0.042	2.117GlnGly: 2.117 ± 0.044	0.827GlnHis: 0.827 ± 0.033	2.509GlnIle: 2.509 ± 0.052	2.483GlnLys: 2.483 ± 0.048	4.565GlnLeu: 4.565 ± 0.079	1.26GlnMet: 1.26 ± 0.032	1.515GlnAsn: 1.515 ± 0.042	1.412GlnPro: 1.412 ± 0.04	2.199GlnGln: 2.199 ± 0.064	1.748GlnArg: 1.748 ± 0.043	2.282GlnSer: 2.282 ± 0.05	2.236GlnThr: 2.236 ± 0.048	2.604GlnVal: 2.604 ± 0.052	0.429GlnTrp: 0.429 ± 0.023	1.256GlnTyr: 1.256 ± 0.031	0.0GlnXaa: 0.0 ± 0.0
Arg	2.808ArgAla: 2.808 ± 0.055	0.293ArgCys: 0.293 ± 0.017	2.188ArgAsp: 2.188 ± 0.048	3.309ArgGlu: 3.309 ± 0.065	2.043ArgPhe: 2.043 ± 0.045	2.5ArgGly: 2.5 ± 0.056	0.857ArgHis: 0.857 ± 0.025	3.165ArgIle: 3.165 ± 0.055	3.365ArgLys: 3.365 ± 0.054	4.367ArgLeu: 4.367 ± 0.07	1.53ArgMet: 1.53 ± 0.038	1.891ArgAsn: 1.891 ± 0.048	1.407ArgPro: 1.407 ± 0.038	1.918ArgGln: 1.918 ± 0.047	2.063ArgArg: 2.063 ± 0.055	2.518ArgSer: 2.518 ± 0.048	2.384ArgThr: 2.384 ± 0.047	2.87ArgVal: 2.87 ± 0.056	0.415ArgTrp: 0.415 ± 0.022	1.532ArgTyr: 1.532 ± 0.039	0.0ArgXaa: 0.0 ± 0.0
Ser	4.287SerAla: 4.287 ± 0.074	0.396SerCys: 0.396 ± 0.02	2.822SerAsp: 2.822 ± 0.047	4.022SerGlu: 4.022 ± 0.065	3.244SerPhe: 3.244 ± 0.057	4.45SerGly: 4.45 ± 0.071	1.159SerHis: 1.159 ± 0.033	4.854SerIle: 4.854 ± 0.076	3.583SerLys: 3.583 ± 0.061	5.983SerLeu: 5.983 ± 0.078	1.855SerMet: 1.855 ± 0.042	2.371SerAsn: 2.371 ± 0.043	2.114SerPro: 2.114 ± 0.043	1.856SerGln: 1.856 ± 0.046	2.474SerArg: 2.474 ± 0.054	3.881SerSer: 3.881 ± 0.079	3.272SerThr: 3.272 ± 0.064	4.414SerVal: 4.414 ± 0.059	0.611SerTrp: 0.611 ± 0.028	2.128SerTyr: 2.128 ± 0.045	0.0SerXaa: 0.0 ± 0.0
Thr	4.52ThrAla: 4.52 ± 0.073	0.367ThrCys: 0.367 ± 0.02	3.034ThrAsp: 3.034 ± 0.064	3.988ThrGlu: 3.988 ± 0.07	2.61ThrPhe: 2.61 ± 0.05	4.286ThrGly: 4.286 ± 0.058	1.118ThrHis: 1.118 ± 0.032	4.592ThrIle: 4.592 ± 0.073	3.251ThrLys: 3.251 ± 0.061	5.182ThrLeu: 5.182 ± 0.078	1.485ThrMet: 1.485 ± 0.039	2.267ThrAsn: 2.267 ± 0.051	2.336ThrPro: 2.336 ± 0.049	1.492ThrGln: 1.492 ± 0.041	1.984ThrArg: 1.984 ± 0.051	3.289ThrSer: 3.289 ± 0.062	3.094ThrThr: 3.094 ± 0.064	4.665ThrVal: 4.665 ± 0.072	0.509ThrTrp: 0.509 ± 0.023	1.899ThrTyr: 1.899 ± 0.048	0.0ThrXaa: 0.0 ± 0.0
Val	5.392ValAla: 5.392 ± 0.073	0.546ValCys: 0.546 ± 0.026	3.809ValAsp: 3.809 ± 0.073	5.128ValGlu: 5.128 ± 0.082	3.243ValPhe: 3.243 ± 0.062	4.767ValGly: 4.767 ± 0.082	1.385ValHis: 1.385 ± 0.036	5.522ValIle: 5.522 ± 0.087	4.54ValLys: 4.54 ± 0.07	7.266ValLeu: 7.266 ± 0.096	2.067ValMet: 2.067 ± 0.039	2.979ValAsn: 2.979 ± 0.06	2.778ValPro: 2.778 ± 0.061	2.625ValGln: 2.625 ± 0.046	2.998ValArg: 2.998 ± 0.059	4.584ValSer: 4.584 ± 0.071	4.219ValThr: 4.219 ± 0.062	5.293ValVal: 5.293 ± 0.087	0.707ValTrp: 0.707 ± 0.029	2.286ValTyr: 2.286 ± 0.045	0.0ValXaa: 0.0 ± 0.0
Trp	0.592TrpAla: 0.592 ± 0.024	0.081TrpCys: 0.081 ± 0.011	0.479TrpAsp: 0.479 ± 0.02	0.624TrpGlu: 0.624 ± 0.025	0.488TrpPhe: 0.488 ± 0.024	0.656TrpGly: 0.656 ± 0.029	0.235TrpHis: 0.235 ± 0.016	0.86TrpIle: 0.86 ± 0.029	0.76TrpLys: 0.76 ± 0.029	1.138TrpLeu: 1.138 ± 0.041	0.327TrpMet: 0.327 ± 0.017	0.47TrpAsn: 0.47 ± 0.023	0.262TrpPro: 0.262 ± 0.018	0.423TrpGln: 0.423 ± 0.021	0.436TrpArg: 0.436 ± 0.02	0.598TrpSer: 0.598 ± 0.025	0.541TrpThr: 0.541 ± 0.026	0.628TrpVal: 0.628 ± 0.026	0.14TrpTrp: 0.14 ± 0.012	0.301TrpTyr: 0.301 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.227TyrAla: 2.227 ± 0.04	0.285TyrCys: 0.285 ± 0.016	1.886TyrAsp: 1.886 ± 0.045	2.464TyrGlu: 2.464 ± 0.047	1.631TyrPhe: 1.631 ± 0.043	2.417TyrGly: 2.417 ± 0.044	0.671TyrHis: 0.671 ± 0.026	2.281TyrIle: 2.281 ± 0.052	1.833TyrLys: 1.833 ± 0.045	3.123TyrLeu: 3.123 ± 0.054	0.885TyrMet: 0.885 ± 0.032	1.156TyrAsn: 1.156 ± 0.032	1.354TyrPro: 1.354 ± 0.038	1.265TyrGln: 1.265 ± 0.036	1.596TyrArg: 1.596 ± 0.043	2.145TyrSer: 2.145 ± 0.045	1.864TyrThr: 1.864 ± 0.046	2.157TyrVal: 2.157 ± 0.049	0.361TyrTrp: 0.361 ± 0.017	1.221TyrTyr: 1.221 ± 0.042	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3825 proteins (1052618 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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