Amino acid dipepetide frequency for Myotis polyomavirus VM-2008

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.743AlaAla: 7.743 ± 2.034
0.0AlaCys: 0.0 ± 0.0
4.978AlaAsp: 4.978 ± 1.728
2.765AlaGlu: 2.765 ± 1.964
2.212AlaPhe: 2.212 ± 1.074
2.765AlaGly: 2.765 ± 0.737
0.553AlaHis: 0.553 ± 0.737
3.872AlaIle: 3.872 ± 0.613
2.765AlaLys: 2.765 ± 0.92
7.743AlaLeu: 7.743 ± 1.8
2.212AlaMet: 2.212 ± 0.89
3.872AlaAsn: 3.872 ± 1.408
2.212AlaPro: 2.212 ± 1.767
4.425AlaGln: 4.425 ± 1.515
8.85AlaArg: 8.85 ± 3.254
1.659AlaSer: 1.659 ± 0.705
2.765AlaThr: 2.765 ± 1.132
6.084AlaVal: 6.084 ± 1.067
0.0AlaTrp: 0.0 ± 0.0
1.659AlaTyr: 1.659 ± 0.757
0.0AlaXaa: 0.0 ± 0.0
Cys
1.106CysAla: 1.106 ± 0.46
0.0CysCys: 0.0 ± 0.0
1.659CysAsp: 1.659 ± 0.699
0.0CysGlu: 0.0 ± 0.0
1.106CysPhe: 1.106 ± 1.474
1.659CysGly: 1.659 ± 0.699
0.0CysHis: 0.0 ± 0.0
0.553CysIle: 0.553 ± 0.737
2.212CysLys: 2.212 ± 0.724
1.659CysLeu: 1.659 ± 0.856
0.0CysMet: 0.0 ± 0.0
1.659CysAsn: 1.659 ± 0.699
0.553CysPro: 0.553 ± 0.516
1.106CysGln: 1.106 ± 0.687
1.659CysArg: 1.659 ± 0.699
1.106CysSer: 1.106 ± 0.687
0.0CysThr: 0.0 ± 0.0
0.553CysVal: 0.553 ± 0.737
0.0CysTrp: 0.0 ± 0.0
2.212CysTyr: 2.212 ± 1.357
0.0CysXaa: 0.0 ± 0.0
Asp
0.553AspAla: 0.553 ± 0.737
1.659AspCys: 1.659 ± 0.856
1.659AspAsp: 1.659 ± 1.221
2.212AspGlu: 2.212 ± 1.628
3.872AspPhe: 3.872 ± 0.844
3.872AspGly: 3.872 ± 0.697
1.106AspHis: 1.106 ± 0.687
5.531AspIle: 5.531 ± 0.98
3.319AspLys: 3.319 ± 0.999
3.872AspLeu: 3.872 ± 1.418
2.765AspMet: 2.765 ± 1.111
3.872AspAsn: 3.872 ± 1.551
1.659AspPro: 1.659 ± 1.547
3.319AspGln: 3.319 ± 1.334
3.872AspArg: 3.872 ± 1.757
2.765AspSer: 2.765 ± 1.427
2.765AspThr: 2.765 ± 0.664
1.659AspVal: 1.659 ± 1.221
1.106AspTrp: 1.106 ± 0.655
5.531AspTyr: 5.531 ± 1.869
0.0AspXaa: 0.0 ± 0.0
Glu
5.531GluAla: 5.531 ± 2.372
1.659GluCys: 1.659 ± 0.856
3.872GluAsp: 3.872 ± 0.48
12.168GluGlu: 12.168 ± 3.56
2.765GluPhe: 2.765 ± 1.427
2.765GluGly: 2.765 ± 1.318
2.765GluHis: 2.765 ± 1.121
0.553GluIle: 0.553 ± 0.516
4.425GluLys: 4.425 ± 0.788
8.296GluLeu: 8.296 ± 1.779
0.553GluMet: 0.553 ± 0.407
3.872GluAsn: 3.872 ± 1.086
4.978GluPro: 4.978 ± 1.453
1.106GluGln: 1.106 ± 0.814
4.425GluArg: 4.425 ± 1.664
4.425GluSer: 4.425 ± 1.977
1.659GluThr: 1.659 ± 0.967
6.084GluVal: 6.084 ± 2.183
1.106GluTrp: 1.106 ± 0.814
1.659GluTyr: 1.659 ± 1.221
0.0GluXaa: 0.0 ± 0.0
Phe
2.765PheAla: 2.765 ± 0.797
1.106PheCys: 1.106 ± 0.687
3.872PheAsp: 3.872 ± 1.735
5.531PheGlu: 5.531 ± 0.98
1.659PhePhe: 1.659 ± 0.699
1.106PheGly: 1.106 ± 0.907
1.106PheHis: 1.106 ± 0.46
2.765PheIle: 2.765 ± 0.707
1.659PheLys: 1.659 ± 0.856
6.084PheLeu: 6.084 ± 2.474
0.553PheMet: 0.553 ± 0.407
2.212PheAsn: 2.212 ± 0.724
4.425PhePro: 4.425 ± 0.46
0.0PheGln: 0.0 ± 0.0
2.212PheArg: 2.212 ± 1.118
3.872PheSer: 3.872 ± 1.27
2.765PheThr: 2.765 ± 0.415
1.659PheVal: 1.659 ± 1.102
0.0PheTrp: 0.0 ± 0.0
1.106PheTyr: 1.106 ± 0.46
0.0PheXaa: 0.0 ± 0.0
Gly
7.19GlyAla: 7.19 ± 2.125
0.553GlyCys: 0.553 ± 0.407
6.637GlyAsp: 6.637 ± 1.577
3.319GlyGlu: 3.319 ± 1.69
2.212GlyPhe: 2.212 ± 1.378
5.531GlyGly: 5.531 ± 0.753
0.0GlyHis: 0.0 ± 0.0
3.872GlyIle: 3.872 ± 1.094
1.659GlyLys: 1.659 ± 1.221
8.85GlyLeu: 8.85 ± 2.143
0.0GlyMet: 0.0 ± 0.0
2.212GlyAsn: 2.212 ± 0.743
4.978GlyPro: 4.978 ± 1.728
4.425GlyGln: 4.425 ± 1.017
1.106GlyArg: 1.106 ± 1.205
0.553GlySer: 0.553 ± 0.516
2.212GlyThr: 2.212 ± 1.357
2.212GlyVal: 2.212 ± 0.92
0.0GlyTrp: 0.0 ± 0.0
0.553GlyTyr: 0.553 ± 0.407
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.553HisGlu: 0.553 ± 0.737
1.106HisPhe: 1.106 ± 0.46
1.106HisGly: 1.106 ± 0.655
0.0HisHis: 0.0 ± 0.0
0.553HisIle: 0.553 ± 0.536
1.659HisLys: 1.659 ± 0.699
1.106HisLeu: 1.106 ± 0.814
0.0HisMet: 0.0 ± 0.0
0.553HisAsn: 0.553 ± 0.407
2.212HisPro: 2.212 ± 0.743
0.0HisGln: 0.0 ± 0.0
2.212HisArg: 2.212 ± 1.047
0.553HisSer: 0.553 ± 0.516
1.659HisThr: 1.659 ± 0.856
0.0HisVal: 0.0 ± 0.0
1.106HisTrp: 1.106 ± 0.655
2.212HisTyr: 2.212 ± 0.684
0.0HisXaa: 0.0 ± 0.0
Ile
2.765IleAla: 2.765 ± 1.964
1.106IleCys: 1.106 ± 0.46
6.084IleAsp: 6.084 ± 1.939
3.319IleGlu: 3.319 ± 1.018
2.765IlePhe: 2.765 ± 1.316
1.106IleGly: 1.106 ± 0.687
1.659IleHis: 1.659 ± 0.531
1.659IleIle: 1.659 ± 0.451
3.319IleLys: 3.319 ± 1.398
4.425IleLeu: 4.425 ± 0.46
1.106IleMet: 1.106 ± 1.29
1.659IleAsn: 1.659 ± 0.695
2.765IlePro: 2.765 ± 0.92
0.553IleGln: 0.553 ± 0.737
1.659IleArg: 1.659 ± 0.757
7.743IleSer: 7.743 ± 1.49
3.872IleThr: 3.872 ± 1.551
1.106IleVal: 1.106 ± 0.655
0.0IleTrp: 0.0 ± 0.0
1.659IleTyr: 1.659 ± 0.531
0.0IleXaa: 0.0 ± 0.0
Lys
3.872LysAla: 3.872 ± 1.217
2.212LysCys: 2.212 ± 0.724
4.425LysAsp: 4.425 ± 2.155
6.084LysGlu: 6.084 ± 1.619
0.553LysPhe: 0.553 ± 0.407
2.212LysGly: 2.212 ± 0.724
1.106LysHis: 1.106 ± 0.814
3.319LysIle: 3.319 ± 1.187
7.743LysLys: 7.743 ± 1.38
2.765LysLeu: 2.765 ± 0.415
1.106LysMet: 1.106 ± 0.46
1.659LysAsn: 1.659 ± 0.889
1.106LysPro: 1.106 ± 0.814
1.659LysGln: 1.659 ± 0.531
8.296LysArg: 8.296 ± 1.966
2.765LysSer: 2.765 ± 0.992
4.978LysThr: 4.978 ± 1.106
2.212LysVal: 2.212 ± 1.357
0.553LysTrp: 0.553 ± 0.407
0.553LysTyr: 0.553 ± 0.516
0.0LysXaa: 0.0 ± 0.0
Leu
9.956LeuAla: 9.956 ± 2.638
3.872LeuCys: 3.872 ± 1.217
2.765LeuAsp: 2.765 ± 1.427
2.765LeuGlu: 2.765 ± 0.53
4.425LeuPhe: 4.425 ± 0.636
5.531LeuGly: 5.531 ± 1.944
1.106LeuHis: 1.106 ± 0.687
5.531LeuIle: 5.531 ± 0.979
1.659LeuLys: 1.659 ± 0.885
10.509LeuLeu: 10.509 ± 1.502
2.212LeuMet: 2.212 ± 0.724
7.19LeuAsn: 7.19 ± 2.227
6.084LeuPro: 6.084 ± 0.947
4.425LeuGln: 4.425 ± 1.12
4.978LeuArg: 4.978 ± 0.649
4.978LeuSer: 4.978 ± 1.15
3.872LeuThr: 3.872 ± 1.233
3.319LeuVal: 3.319 ± 1.161
0.0LeuTrp: 0.0 ± 0.0
6.084LeuTyr: 6.084 ± 1.791
0.0LeuXaa: 0.0 ± 0.0
Met
2.765MetAla: 2.765 ± 0.815
0.0MetCys: 0.0 ± 0.0
3.872MetAsp: 3.872 ± 1.289
1.106MetGlu: 1.106 ± 0.46
0.0MetPhe: 0.0 ± 0.0
2.765MetGly: 2.765 ± 0.805
1.106MetHis: 1.106 ± 0.814
1.106MetIle: 1.106 ± 0.46
1.106MetLys: 1.106 ± 0.814
1.106MetLeu: 1.106 ± 0.655
0.553MetMet: 0.553 ± 0.516
0.0MetAsn: 0.0 ± 0.0
1.659MetPro: 1.659 ± 0.699
0.553MetGln: 0.553 ± 0.516
1.659MetArg: 1.659 ± 1.102
1.106MetSer: 1.106 ± 0.687
1.659MetThr: 1.659 ± 0.531
1.659MetVal: 1.659 ± 0.699
0.553MetTrp: 0.553 ± 0.516
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.765AsnAla: 2.765 ± 1.121
1.106AsnCys: 1.106 ± 0.814
0.0AsnAsp: 0.0 ± 0.0
3.319AsnGlu: 3.319 ± 1.777
3.872AsnPhe: 3.872 ± 0.95
0.553AsnGly: 0.553 ± 0.516
0.553AsnHis: 0.553 ± 0.516
2.212AsnIle: 2.212 ± 0.724
5.531AsnLys: 5.531 ± 1.785
4.425AsnLeu: 4.425 ± 1.192
2.212AsnMet: 2.212 ± 0.454
1.106AsnAsn: 1.106 ± 0.655
3.319AsnPro: 3.319 ± 0.929
1.659AsnGln: 1.659 ± 1.221
3.319AsnArg: 3.319 ± 1.22
1.106AsnSer: 1.106 ± 0.696
2.765AsnThr: 2.765 ± 0.815
1.659AsnVal: 1.659 ± 1.24
1.106AsnTrp: 1.106 ± 0.907
1.659AsnTyr: 1.659 ± 0.531
0.0AsnXaa: 0.0 ± 0.0
Pro
1.659ProAla: 1.659 ± 1.547
0.553ProCys: 0.553 ± 0.516
6.637ProAsp: 6.637 ± 1.19
3.872ProGlu: 3.872 ± 1.047
2.212ProPhe: 2.212 ± 1.151
5.531ProGly: 5.531 ± 1.335
0.0ProHis: 0.0 ± 0.0
4.425ProIle: 4.425 ± 1.36
7.19ProLys: 7.19 ± 1.873
2.765ProLeu: 2.765 ± 1.568
0.0ProMet: 0.0 ± 0.0
2.765ProAsn: 2.765 ± 1.703
5.531ProPro: 5.531 ± 1.278
1.106ProGln: 1.106 ± 1.031
2.765ProArg: 2.765 ± 1.445
4.978ProSer: 4.978 ± 1.007
1.106ProThr: 1.106 ± 0.814
4.425ProVal: 4.425 ± 1.575
0.0ProTrp: 0.0 ± 0.0
2.765ProTyr: 2.765 ± 0.805
0.0ProXaa: 0.0 ± 0.0
Gln
2.765GlnAla: 2.765 ± 1.427
0.0GlnCys: 0.0 ± 0.0
0.553GlnAsp: 0.553 ± 0.516
5.531GlnGlu: 5.531 ± 1.311
4.425GlnPhe: 4.425 ± 1.447
1.659GlnGly: 1.659 ± 0.889
0.553GlnHis: 0.553 ± 0.407
3.319GlnIle: 3.319 ± 0.685
1.659GlnLys: 1.659 ± 0.531
2.212GlnLeu: 2.212 ± 0.455
1.106GlnMet: 1.106 ± 0.46
1.106GlnAsn: 1.106 ± 0.687
2.212GlnPro: 2.212 ± 0.844
1.659GlnGln: 1.659 ± 0.699
4.425GlnArg: 4.425 ± 1.627
4.978GlnSer: 4.978 ± 1.688
0.0GlnThr: 0.0 ± 0.0
3.872GlnVal: 3.872 ± 1.149
1.106GlnTrp: 1.106 ± 0.687
0.553GlnTyr: 0.553 ± 0.407
0.0GlnXaa: 0.0 ± 0.0
Arg
4.425ArgAla: 4.425 ± 1.811
0.553ArgCys: 0.553 ± 0.737
2.212ArgAsp: 2.212 ± 0.724
4.978ArgGlu: 4.978 ± 0.649
3.319ArgPhe: 3.319 ± 1.063
2.765ArgGly: 2.765 ± 0.939
1.659ArgHis: 1.659 ± 1.221
1.659ArgIle: 1.659 ± 1.221
3.319ArgLys: 3.319 ± 1.334
5.531ArgLeu: 5.531 ± 0.941
4.425ArgMet: 4.425 ± 1.064
2.765ArgAsn: 2.765 ± 1.121
2.765ArgPro: 2.765 ± 1.477
2.212ArgGln: 2.212 ± 1.309
7.19ArgArg: 7.19 ± 2.237
6.637ArgSer: 6.637 ± 2.09
3.872ArgThr: 3.872 ± 1.182
2.212ArgVal: 2.212 ± 0.455
1.659ArgTrp: 1.659 ± 1.13
7.743ArgTyr: 7.743 ± 2.363
0.0ArgXaa: 0.0 ± 0.0
Ser
6.637SerAla: 6.637 ± 0.821
1.106SerCys: 1.106 ± 0.88
2.765SerAsp: 2.765 ± 1.318
1.659SerGlu: 1.659 ± 0.699
2.765SerPhe: 2.765 ± 0.415
4.978SerGly: 4.978 ± 1.564
0.553SerHis: 0.553 ± 0.536
1.106SerIle: 1.106 ± 0.696
1.659SerLys: 1.659 ± 0.856
6.637SerLeu: 6.637 ± 0.941
1.659SerMet: 1.659 ± 0.695
0.553SerAsn: 0.553 ± 0.407
3.319SerPro: 3.319 ± 1.063
6.084SerGln: 6.084 ± 2.548
2.765SerArg: 2.765 ± 0.946
3.319SerSer: 3.319 ± 1.572
3.872SerThr: 3.872 ± 1.06
2.212SerVal: 2.212 ± 0.844
2.212SerTrp: 2.212 ± 0.981
1.106SerTyr: 1.106 ± 0.46
0.0SerXaa: 0.0 ± 0.0
Thr
1.659ThrAla: 1.659 ± 0.451
1.659ThrCys: 1.659 ± 0.695
1.106ThrAsp: 1.106 ± 0.814
4.978ThrGlu: 4.978 ± 1.468
1.659ThrPhe: 1.659 ± 0.699
2.765ThrGly: 2.765 ± 0.737
0.0ThrHis: 0.0 ± 0.0
4.978ThrIle: 4.978 ± 1.215
2.212ThrLys: 2.212 ± 1.357
4.425ThrLeu: 4.425 ± 0.46
0.0ThrMet: 0.0 ± 0.0
3.872ThrAsn: 3.872 ± 0.844
6.084ThrPro: 6.084 ± 1.634
4.425ThrGln: 4.425 ± 1.038
1.659ThrArg: 1.659 ± 0.531
0.553ThrSer: 0.553 ± 0.407
4.425ThrThr: 4.425 ± 1.013
4.425ThrVal: 4.425 ± 0.714
0.0ThrTrp: 0.0 ± 0.0
1.106ThrTyr: 1.106 ± 0.476
0.0ThrXaa: 0.0 ± 0.0
Val
3.319ValAla: 3.319 ± 0.622
0.553ValCys: 0.553 ± 0.737
1.659ValAsp: 1.659 ± 0.699
4.978ValGlu: 4.978 ± 0.869
2.765ValPhe: 2.765 ± 0.961
1.659ValGly: 1.659 ± 1.547
1.106ValHis: 1.106 ± 1.031
2.212ValIle: 2.212 ± 0.748
2.212ValLys: 2.212 ± 1.378
4.425ValLeu: 4.425 ± 1.453
0.553ValMet: 0.553 ± 0.516
1.659ValAsn: 1.659 ± 1.036
1.659ValPro: 1.659 ± 0.699
2.212ValGln: 2.212 ± 0.92
2.765ValArg: 2.765 ± 0.815
2.765ValSer: 2.765 ± 1.111
6.637ValThr: 6.637 ± 1.85
1.659ValVal: 1.659 ± 0.889
2.212ValTrp: 2.212 ± 1.357
1.659ValTyr: 1.659 ± 0.699
0.0ValXaa: 0.0 ± 0.0
Trp
1.106TrpAla: 1.106 ± 0.655
0.553TrpCys: 0.553 ± 0.516
0.553TrpAsp: 0.553 ± 0.536
1.106TrpGlu: 1.106 ± 0.46
0.553TrpPhe: 0.553 ± 0.737
3.872TrpGly: 3.872 ± 1.675
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
1.659TrpLys: 1.659 ± 1.036
0.553TrpLeu: 0.553 ± 0.407
1.106TrpMet: 1.106 ± 0.655
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.553TrpGln: 0.553 ± 0.737
0.553TrpArg: 0.553 ± 0.407
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.553TrpTrp: 0.553 ± 0.407
1.106TrpTyr: 1.106 ± 0.862
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.553TyrAla: 0.553 ± 0.407
0.553TyrCys: 0.553 ± 0.737
1.659TyrAsp: 1.659 ± 0.531
4.425TyrGlu: 4.425 ± 0.821
2.212TyrPhe: 2.212 ± 0.455
3.872TyrGly: 3.872 ± 1.399
1.659TyrHis: 1.659 ± 0.531
1.659TyrIle: 1.659 ± 0.531
2.212TyrLys: 2.212 ± 1.151
3.872TyrLeu: 3.872 ± 0.844
1.659TyrMet: 1.659 ± 1.221
1.659TyrAsn: 1.659 ± 0.705
2.765TyrPro: 2.765 ± 1.36
2.212TyrGln: 2.212 ± 0.684
5.531TyrArg: 5.531 ± 1.681
1.106TyrSer: 1.106 ± 0.696
1.106TyrThr: 1.106 ± 0.46
1.659TyrVal: 1.659 ± 0.531
0.553TyrTrp: 0.553 ± 0.407
1.659TyrTyr: 1.659 ± 0.757
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1809 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski