Amino acid dipepetide frequency for Albidovulum xiamenense

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	21.472AlaAla: 21.472 ± 0.257	1.149AlaCys: 1.149 ± 0.035	6.397AlaAsp: 6.397 ± 0.086	11.052AlaGlu: 11.052 ± 0.139	4.577AlaPhe: 4.577 ± 0.081	12.499AlaGly: 12.499 ± 0.132	2.687AlaHis: 2.687 ± 0.052	6.076AlaIle: 6.076 ± 0.084	2.818AlaLys: 2.818 ± 0.062	16.114AlaLeu: 16.114 ± 0.189	3.713AlaMet: 3.713 ± 0.056	2.316AlaAsn: 2.316 ± 0.048	7.327AlaPro: 7.327 ± 0.113	3.886AlaGln: 3.886 ± 0.067	13.655AlaArg: 13.655 ± 0.159	5.271AlaSer: 5.271 ± 0.08	5.657AlaThr: 5.657 ± 0.086	9.389AlaVal: 9.389 ± 0.119	1.792AlaTrp: 1.792 ± 0.046	2.446AlaTyr: 2.446 ± 0.05	0.0AlaXaa: 0.0 ± 0.0
Cys	1.132CysAla: 1.132 ± 0.035	0.089CysCys: 0.089 ± 0.01	0.545CysAsp: 0.545 ± 0.024	0.465CysGlu: 0.465 ± 0.023	0.277CysPhe: 0.277 ± 0.018	0.968CysGly: 0.968 ± 0.036	0.266CysHis: 0.266 ± 0.018	0.367CysIle: 0.367 ± 0.019	0.154CysLys: 0.154 ± 0.014	0.782CysLeu: 0.782 ± 0.029	0.161CysMet: 0.161 ± 0.013	0.198CysAsn: 0.198 ± 0.013	0.54CysPro: 0.54 ± 0.027	0.165CysGln: 0.165 ± 0.014	0.665CysArg: 0.665 ± 0.027	0.364CysSer: 0.364 ± 0.02	0.414CysThr: 0.414 ± 0.023	0.573CysVal: 0.573 ± 0.027	0.119CysTrp: 0.119 ± 0.012	0.196CysTyr: 0.196 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	6.587AspAla: 6.587 ± 0.08	0.483AspCys: 0.483 ± 0.025	2.568AspAsp: 2.568 ± 0.061	3.62AspGlu: 3.62 ± 0.076	2.063AspPhe: 2.063 ± 0.052	4.605AspGly: 4.605 ± 0.075	1.123AspHis: 1.123 ± 0.034	2.698AspIle: 2.698 ± 0.058	1.045AspLys: 1.045 ± 0.034	5.205AspLeu: 5.205 ± 0.084	1.252AspMet: 1.252 ± 0.039	0.933AspAsn: 0.933 ± 0.031	3.798AspPro: 3.798 ± 0.068	1.155AspGln: 1.155 ± 0.034	4.23AspArg: 4.23 ± 0.067	1.76AspSer: 1.76 ± 0.043	2.135AspThr: 2.135 ± 0.052	3.503AspVal: 3.503 ± 0.066	1.134AspTrp: 1.134 ± 0.031	1.305AspTyr: 1.305 ± 0.04	0.0AspXaa: 0.0 ± 0.0
Glu	11.324GluAla: 11.324 ± 0.148	0.375GluCys: 0.375 ± 0.022	3.1GluAsp: 3.1 ± 0.067	5.346GluGlu: 5.346 ± 0.097	1.935GluPhe: 1.935 ± 0.046	6.242GluGly: 6.242 ± 0.086	1.352GluHis: 1.352 ± 0.042	4.161GluIle: 4.161 ± 0.072	2.234GluLys: 2.234 ± 0.052	6.464GluLeu: 6.464 ± 0.101	1.833GluMet: 1.833 ± 0.046	1.51GluAsn: 1.51 ± 0.046	3.261GluPro: 3.261 ± 0.066	1.687GluGln: 1.687 ± 0.041	6.355GluArg: 6.355 ± 0.093	2.203GluSer: 2.203 ± 0.051	3.709GluThr: 3.709 ± 0.062	5.152GluVal: 5.152 ± 0.078	0.886GluTrp: 0.886 ± 0.029	1.05GluTyr: 1.05 ± 0.036	0.0GluXaa: 0.0 ± 0.0
Phe	4.677PheAla: 4.677 ± 0.079	0.388PheCys: 0.388 ± 0.021	2.427PheAsp: 2.427 ± 0.058	2.272PheGlu: 2.272 ± 0.055	1.346PhePhe: 1.346 ± 0.044	3.5PheGly: 3.5 ± 0.07	0.751PheHis: 0.751 ± 0.028	1.554PheIle: 1.554 ± 0.047	0.657PheLys: 0.657 ± 0.026	3.434PheLeu: 3.434 ± 0.067	0.712PheMet: 0.712 ± 0.026	0.837PheAsn: 0.837 ± 0.029	1.614PhePro: 1.614 ± 0.041	0.845PheGln: 0.845 ± 0.028	2.58PheArg: 2.58 ± 0.052	1.809PheSer: 1.809 ± 0.047	1.921PheThr: 1.921 ± 0.043	2.528PheVal: 2.528 ± 0.054	0.572PheTrp: 0.572 ± 0.027	0.847PheTyr: 0.847 ± 0.032	0.0PheXaa: 0.0 ± 0.0
Gly	11.386GlyAla: 11.386 ± 0.124	0.897GlyCys: 0.897 ± 0.034	4.08GlyAsp: 4.08 ± 0.064	6.023GlyGlu: 6.023 ± 0.079	3.533GlyPhe: 3.533 ± 0.068	7.915GlyGly: 7.915 ± 0.109	2.015GlyHis: 2.015 ± 0.047	4.331GlyIle: 4.331 ± 0.075	2.578GlyLys: 2.578 ± 0.061	9.508GlyLeu: 9.508 ± 0.126	2.519GlyMet: 2.519 ± 0.056	1.798GlyAsn: 1.798 ± 0.054	4.212GlyPro: 4.212 ± 0.068	2.669GlyGln: 2.669 ± 0.06	7.952GlyArg: 7.952 ± 0.103	3.657GlySer: 3.657 ± 0.058	4.166GlyThr: 4.166 ± 0.071	6.557GlyVal: 6.557 ± 0.085	1.686GlyTrp: 1.686 ± 0.041	2.096GlyTyr: 2.096 ± 0.05	0.0GlyXaa: 0.0 ± 0.0
His	2.649HisAla: 2.649 ± 0.058	0.218HisCys: 0.218 ± 0.015	1.195HisAsp: 1.195 ± 0.039	1.171HisGlu: 1.171 ± 0.037	0.808HisPhe: 0.808 ± 0.029	2.093HisGly: 2.093 ± 0.046	0.539HisHis: 0.539 ± 0.035	0.871HisIle: 0.871 ± 0.033	0.379HisLys: 0.379 ± 0.02	2.145HisLeu: 2.145 ± 0.048	0.515HisMet: 0.515 ± 0.024	0.365HisAsn: 0.365 ± 0.019	1.503HisPro: 1.503 ± 0.043	0.449HisGln: 0.449 ± 0.021	1.591HisArg: 1.591 ± 0.04	0.725HisSer: 0.725 ± 0.027	0.712HisThr: 0.712 ± 0.028	1.727HisVal: 1.727 ± 0.038	0.355HisTrp: 0.355 ± 0.022	0.541HisTyr: 0.541 ± 0.026	0.0HisXaa: 0.0 ± 0.0
Ile	7.318IleAla: 7.318 ± 0.08	0.52IleCys: 0.52 ± 0.025	3.303IleAsp: 3.303 ± 0.055	3.867IleGlu: 3.867 ± 0.073	1.619IlePhe: 1.619 ± 0.046	4.595IleGly: 4.595 ± 0.081	0.884IleHis: 0.884 ± 0.03	1.974IleIle: 1.974 ± 0.054	0.898IleLys: 0.898 ± 0.038	4.637IleLeu: 4.637 ± 0.073	0.922IleMet: 0.922 ± 0.033	1.074IleAsn: 1.074 ± 0.037	2.292IlePro: 2.292 ± 0.044	0.806IleGln: 0.806 ± 0.027	3.692IleArg: 3.692 ± 0.068	2.406IleSer: 2.406 ± 0.058	2.537IleThr: 2.537 ± 0.049	3.588IleVal: 3.588 ± 0.071	0.654IleTrp: 0.654 ± 0.03	1.032IleTyr: 1.032 ± 0.034	0.0IleXaa: 0.0 ± 0.0
Lys	3.42LysAla: 3.42 ± 0.06	0.141LysCys: 0.141 ± 0.013	1.086LysAsp: 1.086 ± 0.034	1.408LysGlu: 1.408 ± 0.043	0.687LysPhe: 0.687 ± 0.029	2.432LysGly: 2.432 ± 0.057	0.45LysHis: 0.45 ± 0.025	1.261LysIle: 1.261 ± 0.04	0.87LysLys: 0.87 ± 0.038	2.504LysLeu: 2.504 ± 0.058	0.65LysMet: 0.65 ± 0.026	0.543LysAsn: 0.543 ± 0.029	1.568LysPro: 1.568 ± 0.043	0.513LysGln: 0.513 ± 0.028	1.984LysArg: 1.984 ± 0.055	1.167LysSer: 1.167 ± 0.036	1.352LysThr: 1.352 ± 0.04	1.94LysVal: 1.94 ± 0.057	0.306LysTrp: 0.306 ± 0.019	0.499LysTyr: 0.499 ± 0.023	0.0LysXaa: 0.0 ± 0.0
Leu	16.212LeuAla: 16.212 ± 0.168	0.901LeuCys: 0.901 ± 0.033	5.53LeuAsp: 5.53 ± 0.086	6.703LeuGlu: 6.703 ± 0.099	3.428LeuPhe: 3.428 ± 0.072	9.01LeuGly: 9.01 ± 0.119	1.825LeuHis: 1.825 ± 0.048	4.769LeuIle: 4.769 ± 0.081	3.042LeuLys: 3.042 ± 0.068	8.655LeuLeu: 8.655 ± 0.149	2.676LeuMet: 2.676 ± 0.061	2.097LeuAsn: 2.097 ± 0.046	5.854LeuPro: 5.854 ± 0.092	2.185LeuGln: 2.185 ± 0.054	8.083LeuArg: 8.083 ± 0.123	5.548LeuSer: 5.548 ± 0.081	5.239LeuThr: 5.239 ± 0.075	7.521LeuVal: 7.521 ± 0.123	1.53LeuTrp: 1.53 ± 0.045	1.927LeuTyr: 1.927 ± 0.045	0.0LeuXaa: 0.0 ± 0.0
Met	3.459MetAla: 3.459 ± 0.069	0.19MetCys: 0.19 ± 0.014	1.097MetAsp: 1.097 ± 0.032	1.459MetGlu: 1.459 ± 0.04	0.666MetPhe: 0.666 ± 0.03	2.107MetGly: 2.107 ± 0.052	0.458MetHis: 0.458 ± 0.022	1.297MetIle: 1.297 ± 0.035	0.909MetLys: 0.909 ± 0.033	2.485MetLeu: 2.485 ± 0.054	0.602MetMet: 0.602 ± 0.027	0.661MetAsn: 0.661 ± 0.027	1.447MetPro: 1.447 ± 0.041	0.695MetGln: 0.695 ± 0.029	2.173MetArg: 2.173 ± 0.049	1.51MetSer: 1.51 ± 0.039	1.677MetThr: 1.677 ± 0.041	1.759MetVal: 1.759 ± 0.042	0.251MetTrp: 0.251 ± 0.018	0.293MetTyr: 0.293 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	2.728AsnAla: 2.728 ± 0.052	0.213AsnCys: 0.213 ± 0.016	0.988AsnAsp: 0.988 ± 0.039	0.989AsnGlu: 0.989 ± 0.036	0.78AsnPhe: 0.78 ± 0.036	1.844AsnGly: 1.844 ± 0.044	0.401AsnHis: 0.401 ± 0.02	1.117AsnIle: 1.117 ± 0.04	0.376AsnLys: 0.376 ± 0.02	2.063AsnLeu: 2.063 ± 0.048	0.525AsnMet: 0.525 ± 0.022	0.474AsnAsn: 0.474 ± 0.026	1.686AsnPro: 1.686 ± 0.043	0.46AsnGln: 0.46 ± 0.02	1.647AsnArg: 1.647 ± 0.042	0.776AsnSer: 0.776 ± 0.027	0.984AsnThr: 0.984 ± 0.028	1.522AsnVal: 1.522 ± 0.045	0.366AsnTrp: 0.366 ± 0.021	0.521AsnTyr: 0.521 ± 0.022	0.0AsnXaa: 0.0 ± 0.0
Pro	7.423ProAla: 7.423 ± 0.099	0.411ProCys: 0.411 ± 0.021	3.563ProAsp: 3.563 ± 0.062	5.434ProGlu: 5.434 ± 0.079	2.039ProPhe: 2.039 ± 0.048	5.449ProGly: 5.449 ± 0.08	1.192ProHis: 1.192 ± 0.037	2.058ProIle: 2.058 ± 0.048	1.354ProLys: 1.354 ± 0.045	5.061ProLeu: 5.061 ± 0.076	1.237ProMet: 1.237 ± 0.038	1.022ProAsn: 1.022 ± 0.033	3.363ProPro: 3.363 ± 0.085	1.466ProGln: 1.466 ± 0.042	3.984ProArg: 3.984 ± 0.072	2.371ProSer: 2.371 ± 0.052	2.109ProThr: 2.109 ± 0.043	4.625ProVal: 4.625 ± 0.075	0.848ProTrp: 0.848 ± 0.034	1.097ProTyr: 1.097 ± 0.037	0.0ProXaa: 0.0 ± 0.0
Gln	3.605GlnAla: 3.605 ± 0.074	0.165GlnCys: 0.165 ± 0.013	0.956GlnAsp: 0.956 ± 0.036	1.469GlnGlu: 1.469 ± 0.041	0.786GlnPhe: 0.786 ± 0.03	2.265GlnGly: 2.265 ± 0.052	0.44GlnHis: 0.44 ± 0.024	1.526GlnIle: 1.526 ± 0.037	0.76GlnLys: 0.76 ± 0.026	2.405GlnLeu: 2.405 ± 0.053	0.861GlnMet: 0.861 ± 0.028	0.541GlnAsn: 0.541 ± 0.025	1.364GlnPro: 1.364 ± 0.038	0.657GlnGln: 0.657 ± 0.029	2.063GlnArg: 2.063 ± 0.055	1.16GlnSer: 1.16 ± 0.035	1.208GlnThr: 1.208 ± 0.037	1.832GlnVal: 1.832 ± 0.041	0.335GlnTrp: 0.335 ± 0.018	0.432GlnTyr: 0.432 ± 0.019	0.0GlnXaa: 0.0 ± 0.0
Arg	11.917ArgAla: 11.917 ± 0.138	0.55ArgCys: 0.55 ± 0.024	4.203ArgAsp: 4.203 ± 0.074	5.833ArgGlu: 5.833 ± 0.09	3.191ArgPhe: 3.191 ± 0.066	5.926ArgGly: 5.926 ± 0.092	2.021ArgHis: 2.021 ± 0.041	4.346ArgIle: 4.346 ± 0.061	2.072ArgLys: 2.072 ± 0.052	10.251ArgLeu: 10.251 ± 0.143	2.155ArgMet: 2.155 ± 0.045	1.673ArgAsn: 1.673 ± 0.041	4.716ArgPro: 4.716 ± 0.074	2.359ArgGln: 2.359 ± 0.06	8.05ArgArg: 8.05 ± 0.109	3.115ArgSer: 3.115 ± 0.062	2.977ArgThr: 2.977 ± 0.053	5.749ArgVal: 5.749 ± 0.081	1.225ArgTrp: 1.225 ± 0.041	1.668ArgTyr: 1.668 ± 0.045	0.0ArgXaa: 0.0 ± 0.0
Ser	5.286SerAla: 5.286 ± 0.08	0.414SerCys: 0.414 ± 0.021	2.243SerAsp: 2.243 ± 0.055	2.662SerGlu: 2.662 ± 0.059	1.928SerPhe: 1.928 ± 0.046	4.656SerGly: 4.656 ± 0.081	0.924SerHis: 0.924 ± 0.032	1.886SerIle: 1.886 ± 0.056	0.915SerLys: 0.915 ± 0.032	4.36SerLeu: 4.36 ± 0.073	1.071SerMet: 1.071 ± 0.033	0.901SerAsn: 0.901 ± 0.03	2.525SerPro: 2.525 ± 0.057	1.065SerGln: 1.065 ± 0.03	3.483SerArg: 3.483 ± 0.066	1.847SerSer: 1.847 ± 0.047	1.898SerThr: 1.898 ± 0.042	3.098SerVal: 3.098 ± 0.051	0.676SerTrp: 0.676 ± 0.024	1.013SerTyr: 1.013 ± 0.032	0.0SerXaa: 0.0 ± 0.0
Thr	5.843ThrAla: 5.843 ± 0.079	0.387ThrCys: 0.387 ± 0.025	2.39ThrAsp: 2.39 ± 0.05	2.804ThrGlu: 2.804 ± 0.059	1.533ThrPhe: 1.533 ± 0.042	5.134ThrGly: 5.134 ± 0.076	0.945ThrHis: 0.945 ± 0.034	2.269ThrIle: 2.269 ± 0.046	0.93ThrLys: 0.93 ± 0.035	5.304ThrLeu: 5.304 ± 0.079	1.018ThrMet: 1.018 ± 0.036	0.911ThrAsn: 0.911 ± 0.035	3.354ThrPro: 3.354 ± 0.053	0.993ThrGln: 0.993 ± 0.035	3.627ThrArg: 3.627 ± 0.061	1.993ThrSer: 1.993 ± 0.047	2.211ThrThr: 2.211 ± 0.05	3.814ThrVal: 3.814 ± 0.054	0.612ThrTrp: 0.612 ± 0.025	0.872ThrTyr: 0.872 ± 0.031	0.0ThrXaa: 0.0 ± 0.0
Val	9.772ValAla: 9.772 ± 0.137	0.58ValCys: 0.58 ± 0.027	3.564ValAsp: 3.564 ± 0.07	5.392ValGlu: 5.392 ± 0.081	2.734ValPhe: 2.734 ± 0.058	5.309ValGly: 5.309 ± 0.09	1.389ValHis: 1.389 ± 0.042	4.566ValIle: 4.566 ± 0.076	1.944ValLys: 1.944 ± 0.055	7.333ValLeu: 7.333 ± 0.087	1.959ValMet: 1.959 ± 0.05	1.755ValAsn: 1.755 ± 0.046	3.815ValPro: 3.815 ± 0.069	1.646ValGln: 1.646 ± 0.044	4.933ValArg: 4.933 ± 0.069	3.625ValSer: 3.625 ± 0.07	4.439ValThr: 4.439 ± 0.071	5.857ValVal: 5.857 ± 0.101	0.998ValTrp: 0.998 ± 0.036	1.415ValTyr: 1.415 ± 0.039	0.0ValXaa: 0.0 ± 0.0
Trp	1.642TrpAla: 1.642 ± 0.048	0.13TrpCys: 0.13 ± 0.012	0.666TrpAsp: 0.666 ± 0.029	0.906TrpGlu: 0.906 ± 0.032	0.572TrpPhe: 0.572 ± 0.027	1.081TrpGly: 1.081 ± 0.032	0.39TrpHis: 0.39 ± 0.02	0.648TrpIle: 0.648 ± 0.026	0.432TrpLys: 0.432 ± 0.021	1.94TrpLeu: 1.94 ± 0.048	0.392TrpMet: 0.392 ± 0.022	0.374TrpAsn: 0.374 ± 0.023	0.839TrpPro: 0.839 ± 0.027	0.594TrpGln: 0.594 ± 0.024	1.533TrpArg: 1.533 ± 0.045	0.711TrpSer: 0.711 ± 0.029	0.661TrpThr: 0.661 ± 0.027	0.921TrpVal: 0.921 ± 0.032	0.247TrpTrp: 0.247 ± 0.019	0.256TrpTyr: 0.256 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.442TyrAla: 2.442 ± 0.059	0.236TyrCys: 0.236 ± 0.014	1.303TyrAsp: 1.303 ± 0.043	1.303TyrGlu: 1.303 ± 0.043	0.768TyrPhe: 0.768 ± 0.03	1.946TyrGly: 1.946 ± 0.054	0.496TyrHis: 0.496 ± 0.024	0.844TyrIle: 0.844 ± 0.03	0.414TyrLys: 0.414 ± 0.022	2.087TyrLeu: 2.087 ± 0.049	0.422TyrMet: 0.422 ± 0.023	0.479TyrAsn: 0.479 ± 0.026	1.03TyrPro: 1.03 ± 0.038	0.534TyrGln: 0.534 ± 0.025	1.718TyrArg: 1.718 ± 0.047	0.832TyrSer: 0.832 ± 0.029	0.934TyrThr: 0.934 ± 0.035	1.37TyrVal: 1.37 ± 0.041	0.346TyrTrp: 0.346 ± 0.021	0.499TyrTyr: 0.499 ± 0.026	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3011 proteins (956227 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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