Amino acid dipepetide frequency for Jingmen tombus-like virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
10.861AlaAla: 10.861 ± 0.779
1.498AlaCys: 1.498 ± 0.664
4.869AlaAsp: 4.869 ± 0.638
5.993AlaGlu: 5.993 ± 2.937
2.622AlaPhe: 2.622 ± 1.162
8.614AlaGly: 8.614 ± 1.022
1.873AlaHis: 1.873 ± 0.83
3.371AlaIle: 3.371 ± 1.494
1.873AlaLys: 1.873 ± 0.83
8.989AlaLeu: 8.989 ± 1.609
1.498AlaMet: 1.498 ± 0.6
3.745AlaAsn: 3.745 ± 1.66
8.614AlaPro: 8.614 ± 3.818
3.371AlaGln: 3.371 ± 1.302
8.614AlaArg: 8.614 ± 1.775
8.614AlaSer: 8.614 ± 1.022
5.993AlaThr: 5.993 ± 5.733
6.742AlaVal: 6.742 ± 5.401
0.749AlaTrp: 0.749 ± 0.332
3.745AlaTyr: 3.745 ± 1.66
0.0AlaXaa: 0.0 ± 0.0
Cys
3.371CysAla: 3.371 ± 1.494
0.749CysCys: 0.749 ± 0.332
0.375CysAsp: 0.375 ± 0.166
0.749CysGlu: 0.749 ± 0.332
0.375CysPhe: 0.375 ± 0.166
0.749CysGly: 0.749 ± 0.332
0.0CysHis: 0.0 ± 0.0
0.749CysIle: 0.749 ± 0.332
2.247CysLys: 2.247 ± 0.996
1.498CysLeu: 1.498 ± 0.664
0.375CysMet: 0.375 ± 0.166
0.375CysAsn: 0.375 ± 0.166
0.749CysPro: 0.749 ± 0.332
0.0CysGln: 0.0 ± 0.0
1.498CysArg: 1.498 ± 4.929
1.124CysSer: 1.124 ± 0.498
0.749CysThr: 0.749 ± 0.332
2.996CysVal: 2.996 ± 1.328
1.124CysTrp: 1.124 ± 0.498
1.873CysTyr: 1.873 ± 0.83
0.0CysXaa: 0.0 ± 0.0
Asp
6.742AspAla: 6.742 ± 0.192
1.124AspCys: 1.124 ± 0.498
3.371AspAsp: 3.371 ± 1.302
3.371AspGlu: 3.371 ± 1.302
1.498AspPhe: 1.498 ± 0.664
3.745AspGly: 3.745 ± 1.136
1.124AspHis: 1.124 ± 0.498
1.498AspIle: 1.498 ± 0.664
2.247AspLys: 2.247 ± 0.996
5.993AspLeu: 5.993 ± 2.937
1.124AspMet: 1.124 ± 2.298
1.124AspAsn: 1.124 ± 0.498
2.622AspPro: 2.622 ± 1.162
2.247AspGln: 2.247 ± 0.996
2.996AspArg: 2.996 ± 1.468
4.12AspSer: 4.12 ± 1.826
3.371AspThr: 3.371 ± 1.494
4.869AspVal: 4.869 ± 3.435
2.622AspTrp: 2.622 ± 1.162
1.873AspTyr: 1.873 ± 0.83
0.0AspXaa: 0.0 ± 0.0
Glu
6.367GluAla: 6.367 ± 2.771
0.375GluCys: 0.375 ± 0.166
2.622GluAsp: 2.622 ± 1.162
2.622GluGlu: 2.622 ± 1.162
0.749GluPhe: 0.749 ± 0.332
2.996GluGly: 2.996 ± 1.328
2.247GluHis: 2.247 ± 0.996
1.498GluIle: 1.498 ± 0.664
0.375GluLys: 0.375 ± 0.166
8.614GluLeu: 8.614 ± 1.775
1.498GluMet: 1.498 ± 0.669
0.0GluAsn: 0.0 ± 0.0
4.494GluPro: 4.494 ± 1.992
1.124GluGln: 1.124 ± 2.298
4.12GluArg: 4.12 ± 3.767
2.996GluSer: 2.996 ± 4.265
2.247GluThr: 2.247 ± 0.996
4.12GluVal: 4.12 ± 0.97
1.498GluTrp: 1.498 ± 0.664
1.124GluTyr: 1.124 ± 0.498
0.0GluXaa: 0.0 ± 0.0
Phe
1.873PheAla: 1.873 ± 0.83
0.749PheCys: 0.749 ± 0.332
1.873PheAsp: 1.873 ± 0.83
2.247PheGlu: 2.247 ± 0.996
0.375PhePhe: 0.375 ± 0.166
2.622PheGly: 2.622 ± 1.634
1.124PheHis: 1.124 ± 0.498
0.749PheIle: 0.749 ± 0.332
0.0PheLys: 0.0 ± 0.0
1.873PheLeu: 1.873 ± 0.83
1.498PheMet: 1.498 ± 0.664
0.749PheAsn: 0.749 ± 0.332
0.749PhePro: 0.749 ± 0.332
1.124PheGln: 1.124 ± 0.498
2.247PheArg: 2.247 ± 0.996
2.247PheSer: 2.247 ± 0.996
0.749PheThr: 0.749 ± 0.332
3.371PheVal: 3.371 ± 1.494
0.749PheTrp: 0.749 ± 0.332
0.749PheTyr: 0.749 ± 2.465
0.0PheXaa: 0.0 ± 0.0
Gly
7.116GlyAla: 7.116 ± 2.439
0.749GlyCys: 0.749 ± 0.332
2.996GlyAsp: 2.996 ± 1.328
4.494GlyGlu: 4.494 ± 0.804
2.247GlyPhe: 2.247 ± 0.996
3.745GlyGly: 3.745 ± 1.136
3.371GlyHis: 3.371 ± 1.302
4.12GlyIle: 4.12 ± 1.826
2.996GlyLys: 2.996 ± 1.328
3.371GlyLeu: 3.371 ± 1.494
1.498GlyMet: 1.498 ± 0.664
1.873GlyAsn: 1.873 ± 0.83
4.494GlyPro: 4.494 ± 1.992
1.873GlyGln: 1.873 ± 0.83
5.243GlyArg: 5.243 ± 0.472
6.367GlySer: 6.367 ± 2.771
5.618GlyThr: 5.618 ± 2.49
9.363GlyVal: 9.363 ± 4.15
2.622GlyTrp: 2.622 ± 1.162
1.498GlyTyr: 1.498 ± 0.664
0.0GlyXaa: 0.0 ± 0.0
His
1.124HisAla: 1.124 ± 2.298
0.749HisCys: 0.749 ± 0.332
1.873HisAsp: 1.873 ± 0.83
1.873HisGlu: 1.873 ± 1.966
0.749HisPhe: 0.749 ± 0.332
1.873HisGly: 1.873 ± 0.83
0.749HisHis: 0.749 ± 2.465
1.498HisIle: 1.498 ± 0.664
0.749HisLys: 0.749 ± 0.332
1.873HisLeu: 1.873 ± 1.966
0.749HisMet: 0.749 ± 0.332
0.749HisAsn: 0.749 ± 0.332
2.622HisPro: 2.622 ± 1.162
0.0HisGln: 0.0 ± 0.0
0.749HisArg: 0.749 ± 0.332
2.996HisSer: 2.996 ± 1.328
0.749HisThr: 0.749 ± 0.332
2.247HisVal: 2.247 ± 1.8
0.749HisTrp: 0.749 ± 0.332
1.873HisTyr: 1.873 ± 0.83
0.0HisXaa: 0.0 ± 0.0
Ile
3.371IleAla: 3.371 ± 1.494
0.749IleCys: 0.749 ± 2.465
2.622IleAsp: 2.622 ± 1.634
2.247IleGlu: 2.247 ± 0.996
1.873IlePhe: 1.873 ± 0.83
2.247IleGly: 2.247 ± 0.996
2.996IleHis: 2.996 ± 1.468
1.873IleIle: 1.873 ± 0.83
0.749IleLys: 0.749 ± 0.332
2.247IleLeu: 2.247 ± 0.996
0.375IleMet: 0.375 ± 0.166
2.247IleAsn: 2.247 ± 0.996
3.371IlePro: 3.371 ± 1.494
0.749IleGln: 0.749 ± 0.332
1.873IleArg: 1.873 ± 1.966
1.498IleSer: 1.498 ± 0.664
1.873IleThr: 1.873 ± 0.83
1.873IleVal: 1.873 ± 0.83
0.375IleTrp: 0.375 ± 0.166
2.247IleTyr: 2.247 ± 0.996
0.0IleXaa: 0.0 ± 0.0
Lys
2.996LysAla: 2.996 ± 1.328
0.749LysCys: 0.749 ± 0.332
2.996LysAsp: 2.996 ± 1.328
0.749LysGlu: 0.749 ± 0.332
0.749LysPhe: 0.749 ± 0.332
2.622LysGly: 2.622 ± 1.162
0.0LysHis: 0.0 ± 0.0
2.247LysIle: 2.247 ± 0.996
1.873LysLys: 1.873 ± 0.83
1.873LysLeu: 1.873 ± 0.83
0.749LysMet: 0.749 ± 0.332
1.498LysAsn: 1.498 ± 0.664
2.996LysPro: 2.996 ± 1.328
0.375LysGln: 0.375 ± 0.166
1.873LysArg: 1.873 ± 0.83
3.745LysSer: 3.745 ± 1.66
1.498LysThr: 1.498 ± 0.664
1.498LysVal: 1.498 ± 0.664
0.0LysTrp: 0.0 ± 0.0
0.749LysTyr: 0.749 ± 0.332
0.0LysXaa: 0.0 ± 0.0
Leu
8.614LeuAla: 8.614 ± 1.775
1.873LeuCys: 1.873 ± 0.83
7.865LeuAsp: 7.865 ± 2.107
4.12LeuGlu: 4.12 ± 1.826
1.124LeuPhe: 1.124 ± 0.498
6.742LeuGly: 6.742 ± 0.192
2.622LeuHis: 2.622 ± 1.162
2.996LeuIle: 2.996 ± 1.468
2.622LeuLys: 2.622 ± 1.162
7.116LeuLeu: 7.116 ± 8.032
1.124LeuMet: 1.124 ± 0.498
1.873LeuAsn: 1.873 ± 0.83
7.116LeuPro: 7.116 ± 3.154
1.873LeuGln: 1.873 ± 4.763
7.116LeuArg: 7.116 ± 5.235
5.993LeuSer: 5.993 ± 2.937
6.367LeuThr: 6.367 ± 5.567
7.116LeuVal: 7.116 ± 2.439
0.375LeuTrp: 0.375 ± 0.166
1.498LeuTyr: 1.498 ± 0.664
0.0LeuXaa: 0.0 ± 0.0
Met
2.247MetAla: 2.247 ± 1.8
0.749MetCys: 0.749 ± 0.332
0.749MetAsp: 0.749 ± 0.332
0.375MetGlu: 0.375 ± 0.166
0.0MetPhe: 0.0 ± 0.0
1.873MetGly: 1.873 ± 0.83
1.124MetHis: 1.124 ± 0.498
0.375MetIle: 0.375 ± 0.166
0.0MetLys: 0.0 ± 0.0
0.749MetLeu: 0.749 ± 0.332
0.375MetMet: 0.375 ± 0.166
0.375MetAsn: 0.375 ± 0.166
1.873MetPro: 1.873 ± 0.83
0.0MetGln: 0.0 ± 0.0
2.622MetArg: 2.622 ± 1.634
2.622MetSer: 2.622 ± 1.634
1.498MetThr: 1.498 ± 0.664
1.873MetVal: 1.873 ± 0.83
0.749MetTrp: 0.749 ± 0.332
0.375MetTyr: 0.375 ± 0.166
0.0MetXaa: 0.0 ± 0.0
Asn
2.247AsnAla: 2.247 ± 0.996
0.375AsnCys: 0.375 ± 0.166
2.247AsnAsp: 2.247 ± 0.996
1.498AsnGlu: 1.498 ± 0.664
0.375AsnPhe: 0.375 ± 0.166
4.869AsnGly: 4.869 ± 2.158
0.0AsnHis: 0.0 ± 0.0
1.124AsnIle: 1.124 ± 2.298
0.375AsnLys: 0.375 ± 0.166
2.996AsnLeu: 2.996 ± 1.328
1.498AsnMet: 1.498 ± 0.664
0.375AsnAsn: 0.375 ± 0.166
1.124AsnPro: 1.124 ± 0.498
0.375AsnGln: 0.375 ± 0.166
2.247AsnArg: 2.247 ± 0.996
2.622AsnSer: 2.622 ± 1.162
0.749AsnThr: 0.749 ± 0.332
2.247AsnVal: 2.247 ± 0.996
1.124AsnTrp: 1.124 ± 0.498
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
3.745ProAla: 3.745 ± 1.66
3.371ProCys: 3.371 ± 1.494
2.996ProAsp: 2.996 ± 1.328
1.498ProGlu: 1.498 ± 0.664
2.247ProPhe: 2.247 ± 0.996
5.243ProGly: 5.243 ± 2.324
0.749ProHis: 0.749 ± 0.332
3.371ProIle: 3.371 ± 1.494
1.873ProLys: 1.873 ± 0.83
8.24ProLeu: 8.24 ± 3.652
1.124ProMet: 1.124 ± 0.498
2.247ProAsn: 2.247 ± 0.996
3.371ProPro: 3.371 ± 1.494
0.749ProGln: 0.749 ± 0.332
2.247ProArg: 2.247 ± 0.996
2.996ProSer: 2.996 ± 1.328
5.243ProThr: 5.243 ± 0.472
4.494ProVal: 4.494 ± 1.992
3.371ProTrp: 3.371 ± 1.494
1.873ProTyr: 1.873 ± 0.83
0.0ProXaa: 0.0 ± 0.0
Gln
2.996GlnAla: 2.996 ± 1.328
0.375GlnCys: 0.375 ± 0.166
1.873GlnAsp: 1.873 ± 1.966
1.873GlnGlu: 1.873 ± 1.966
1.124GlnPhe: 1.124 ± 0.498
1.498GlnGly: 1.498 ± 0.664
0.0GlnHis: 0.0 ± 0.0
2.247GlnIle: 2.247 ± 1.8
1.498GlnLys: 1.498 ± 0.664
1.873GlnLeu: 1.873 ± 0.83
0.749GlnMet: 0.749 ± 0.332
0.0GlnAsn: 0.0 ± 0.0
1.124GlnPro: 1.124 ± 0.498
0.749GlnGln: 0.749 ± 0.332
2.622GlnArg: 2.622 ± 4.431
1.124GlnSer: 1.124 ± 2.298
0.375GlnThr: 0.375 ± 0.166
1.873GlnVal: 1.873 ± 0.83
1.124GlnTrp: 1.124 ± 2.298
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
9.738ArgAla: 9.738 ± 1.277
0.749ArgCys: 0.749 ± 0.332
3.371ArgAsp: 3.371 ± 1.302
4.12ArgGlu: 4.12 ± 6.563
4.12ArgPhe: 4.12 ± 0.97
5.993ArgGly: 5.993 ± 0.14
1.873ArgHis: 1.873 ± 1.966
1.498ArgIle: 1.498 ± 0.664
1.873ArgLys: 1.873 ± 0.83
7.116ArgLeu: 7.116 ± 13.625
1.873ArgMet: 1.873 ± 0.83
3.371ArgAsn: 3.371 ± 1.302
2.996ArgPro: 2.996 ± 1.328
1.498ArgGln: 1.498 ± 2.132
9.363ArgArg: 9.363 ± 9.832
3.371ArgSer: 3.371 ± 1.302
4.494ArgThr: 4.494 ± 3.601
5.243ArgVal: 5.243 ± 2.324
1.498ArgTrp: 1.498 ± 0.664
3.371ArgTyr: 3.371 ± 1.494
0.0ArgXaa: 0.0 ± 0.0
Ser
6.742SerAla: 6.742 ± 0.192
1.873SerCys: 1.873 ± 0.83
2.996SerAsp: 2.996 ± 1.468
4.869SerGlu: 4.869 ± 0.638
2.247SerPhe: 2.247 ± 0.996
6.367SerGly: 6.367 ± 0.026
0.749SerHis: 0.749 ± 0.332
2.622SerIle: 2.622 ± 1.162
0.749SerLys: 0.749 ± 0.332
6.367SerLeu: 6.367 ± 2.771
1.498SerMet: 1.498 ± 2.132
2.247SerAsn: 2.247 ± 0.996
3.371SerPro: 3.371 ± 1.302
2.622SerGln: 2.622 ± 1.634
5.993SerArg: 5.993 ± 0.14
5.243SerSer: 5.243 ± 2.324
5.243SerThr: 5.243 ± 2.324
6.742SerVal: 6.742 ± 2.605
1.873SerTrp: 1.873 ± 0.83
3.371SerTyr: 3.371 ± 1.494
0.0SerXaa: 0.0 ± 0.0
Thr
6.367ThrAla: 6.367 ± 2.771
0.749ThrCys: 0.749 ± 0.332
2.996ThrAsp: 2.996 ± 1.328
2.247ThrGlu: 2.247 ± 0.996
1.498ThrPhe: 1.498 ± 2.132
6.367ThrGly: 6.367 ± 0.026
1.124ThrHis: 1.124 ± 2.298
1.498ThrIle: 1.498 ± 0.664
1.873ThrLys: 1.873 ± 0.83
4.12ThrLeu: 4.12 ± 0.97
0.375ThrMet: 0.375 ± 0.166
3.371ThrAsn: 3.371 ± 1.494
3.371ThrPro: 3.371 ± 1.494
1.124ThrGln: 1.124 ± 0.498
5.993ThrArg: 5.993 ± 2.937
5.618ThrSer: 5.618 ± 2.49
4.12ThrThr: 4.12 ± 3.767
2.247ThrVal: 2.247 ± 0.996
1.124ThrTrp: 1.124 ± 0.498
1.873ThrTyr: 1.873 ± 1.966
0.0ThrXaa: 0.0 ± 0.0
Val
11.985ValAla: 11.985 ± 0.281
2.247ValCys: 2.247 ± 1.8
5.993ValAsp: 5.993 ± 2.937
3.745ValGlu: 3.745 ± 1.66
1.873ValPhe: 1.873 ± 0.83
4.869ValGly: 4.869 ± 2.158
0.749ValHis: 0.749 ± 0.332
2.247ValIle: 2.247 ± 1.8
4.12ValLys: 4.12 ± 1.826
5.993ValLeu: 5.993 ± 2.937
1.124ValMet: 1.124 ± 0.498
1.124ValAsn: 1.124 ± 0.498
4.12ValPro: 4.12 ± 1.826
4.12ValGln: 4.12 ± 0.97
5.618ValArg: 5.618 ± 0.306
6.367ValSer: 6.367 ± 0.026
2.996ValThr: 2.996 ± 1.328
4.869ValVal: 4.869 ± 0.638
1.124ValTrp: 1.124 ± 2.298
3.745ValTyr: 3.745 ± 1.66
0.0ValXaa: 0.0 ± 0.0
Trp
2.622TrpAla: 2.622 ± 1.162
0.375TrpCys: 0.375 ± 0.166
2.247TrpAsp: 2.247 ± 0.996
1.124TrpGlu: 1.124 ± 2.298
0.749TrpPhe: 0.749 ± 0.332
1.498TrpGly: 1.498 ± 0.664
1.124TrpHis: 1.124 ± 0.498
0.375TrpIle: 0.375 ± 0.166
1.124TrpLys: 1.124 ± 0.498
1.873TrpLeu: 1.873 ± 0.83
0.749TrpMet: 0.749 ± 0.332
0.749TrpAsn: 0.749 ± 0.332
1.498TrpPro: 1.498 ± 0.664
0.749TrpGln: 0.749 ± 0.332
1.498TrpArg: 1.498 ± 0.664
0.375TrpSer: 0.375 ± 0.166
1.498TrpThr: 1.498 ± 0.664
2.247TrpVal: 2.247 ± 1.8
0.375TrpTrp: 0.375 ± 0.166
0.749TrpTyr: 0.749 ± 0.332
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.124TyrAla: 1.124 ± 0.498
1.498TyrCys: 1.498 ± 0.664
0.749TyrAsp: 0.749 ± 0.332
2.247TyrGlu: 2.247 ± 0.996
1.124TyrPhe: 1.124 ± 0.498
1.124TyrGly: 1.124 ± 0.498
2.996TyrHis: 2.996 ± 1.328
1.498TyrIle: 1.498 ± 0.664
2.622TyrLys: 2.622 ± 1.162
3.371TyrLeu: 3.371 ± 1.494
0.375TyrMet: 0.375 ± 0.166
0.375TyrAsn: 0.375 ± 0.166
0.375TyrPro: 0.375 ± 0.166
0.375TyrGln: 0.375 ± 0.166
2.996TyrArg: 2.996 ± 1.468
3.745TyrSer: 3.745 ± 1.136
2.622TyrThr: 2.622 ± 1.162
2.996TyrVal: 2.996 ± 1.328
0.375TyrTrp: 0.375 ± 0.166
1.498TyrTyr: 1.498 ± 0.664
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2671 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski