Amino acid dipepetide frequency for Beihai picorna-like virus 79

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.53AlaAla: 4.53 ± 0.976
1.133AlaCys: 1.133 ± 0.658
2.643AlaAsp: 2.643 ± 1.558
4.153AlaGlu: 4.153 ± 0.68
5.663AlaPhe: 5.663 ± 1.349
4.53AlaGly: 4.53 ± 0.571
1.888AlaHis: 1.888 ± 0.066
3.02AlaIle: 3.02 ± 0.822
3.775AlaLys: 3.775 ± 1.163
5.663AlaLeu: 5.663 ± 1.745
2.643AlaMet: 2.643 ± 0.505
5.663AlaAsn: 5.663 ± 1.864
3.398AlaPro: 3.398 ± 1.634
2.265AlaGln: 2.265 ± 0.286
3.775AlaArg: 3.775 ± 0.648
4.53AlaSer: 4.53 ± 1.492
4.153AlaThr: 4.153 ± 0.352
5.285AlaVal: 5.285 ± 1.053
2.643AlaTrp: 2.643 ± 0.505
1.51AlaTyr: 1.51 ± 0.362
0.0AlaXaa: 0.0 ± 0.0
Cys
1.51CysAla: 1.51 ± 0.362
0.378CysCys: 0.378 ± 0.219
2.643CysAsp: 2.643 ± 1.536
1.133CysGlu: 1.133 ± 0.143
1.51CysPhe: 1.51 ± 0.362
1.888CysGly: 1.888 ± 1.097
0.378CysHis: 0.378 ± 0.219
0.755CysIle: 0.755 ± 0.592
1.51CysLys: 1.51 ± 0.362
1.51CysLeu: 1.51 ± 0.153
0.0CysMet: 0.0 ± 0.0
0.755CysAsn: 0.755 ± 0.077
1.133CysPro: 1.133 ± 0.889
0.755CysGln: 0.755 ± 0.077
0.755CysArg: 0.755 ± 0.439
0.378CysSer: 0.378 ± 0.219
0.378CysThr: 0.378 ± 0.219
1.133CysVal: 1.133 ± 0.658
0.378CysTrp: 0.378 ± 0.219
0.378CysTyr: 0.378 ± 0.296
0.0CysXaa: 0.0 ± 0.0
Asp
3.775AspAla: 3.775 ± 0.648
0.755AspCys: 0.755 ± 0.439
4.53AspAsp: 4.53 ± 2.007
6.04AspGlu: 6.04 ± 1.965
4.908AspPhe: 4.908 ± 0.275
5.285AspGly: 5.285 ± 2.6
0.378AspHis: 0.378 ± 0.219
4.908AspIle: 4.908 ± 0.275
3.398AspLys: 3.398 ± 0.428
6.418AspLeu: 6.418 ± 0.394
2.643AspMet: 2.643 ± 1.042
3.398AspAsn: 3.398 ± 0.603
2.265AspPro: 2.265 ± 0.746
0.755AspGln: 0.755 ± 0.077
2.643AspArg: 2.643 ± 0.011
3.02AspSer: 3.02 ± 0.725
2.265AspThr: 2.265 ± 0.23
3.398AspVal: 3.398 ± 0.428
0.755AspTrp: 0.755 ± 0.592
3.775AspTyr: 3.775 ± 0.899
0.0AspXaa: 0.0 ± 0.0
Glu
4.153GluAla: 4.153 ± 0.164
1.133GluCys: 1.133 ± 0.143
3.02GluAsp: 3.02 ± 0.307
2.265GluGlu: 2.265 ± 0.801
3.775GluPhe: 3.775 ± 1.163
2.643GluGly: 2.643 ± 0.011
0.0GluHis: 0.0 ± 0.0
5.285GluIle: 5.285 ± 1.526
3.02GluLys: 3.02 ± 0.209
2.265GluLeu: 2.265 ± 0.746
1.888GluMet: 1.888 ± 0.066
3.775GluAsn: 3.775 ± 1.679
2.643GluPro: 2.643 ± 1.042
1.51GluGln: 1.51 ± 0.362
2.643GluArg: 2.643 ± 0.011
5.663GluSer: 5.663 ± 0.714
3.02GluThr: 3.02 ± 1.24
2.643GluVal: 2.643 ± 0.505
1.51GluTrp: 1.51 ± 0.362
1.888GluTyr: 1.888 ± 0.066
0.0GluXaa: 0.0 ± 0.0
Phe
4.908PheAla: 4.908 ± 0.241
0.378PheCys: 0.378 ± 0.219
5.663PheAsp: 5.663 ± 0.714
3.398PheGlu: 3.398 ± 0.603
1.51PhePhe: 1.51 ± 0.362
4.153PheGly: 4.153 ± 0.352
1.133PheHis: 1.133 ± 0.143
2.265PheIle: 2.265 ± 0.286
3.02PheLys: 3.02 ± 0.725
4.53PheLeu: 4.53 ± 0.46
3.398PheMet: 3.398 ± 0.944
2.643PheAsn: 2.643 ± 0.526
2.265PhePro: 2.265 ± 0.23
1.51PheGln: 1.51 ± 0.153
3.398PheArg: 3.398 ± 0.428
3.775PheSer: 3.775 ± 0.383
3.398PheThr: 3.398 ± 1.119
1.51PheVal: 1.51 ± 0.153
1.133PheTrp: 1.133 ± 0.373
2.643PheTyr: 2.643 ± 2.073
0.0PheXaa: 0.0 ± 0.0
Gly
5.285GlyAla: 5.285 ± 1.053
1.51GlyCys: 1.51 ± 0.362
3.775GlyAsp: 3.775 ± 1.163
3.398GlyGlu: 3.398 ± 0.944
2.265GlyPhe: 2.265 ± 1.261
4.908GlyGly: 4.908 ± 1.272
0.755GlyHis: 0.755 ± 0.439
2.643GlyIle: 2.643 ± 1.042
4.53GlyLys: 4.53 ± 1.602
3.02GlyLeu: 3.02 ± 0.307
0.755GlyMet: 0.755 ± 0.077
1.133GlyAsn: 1.133 ± 0.889
3.775GlyPro: 3.775 ± 0.132
3.775GlyGln: 3.775 ± 0.899
2.643GlyArg: 2.643 ± 0.011
4.908GlySer: 4.908 ± 0.756
4.153GlyThr: 4.153 ± 1.711
2.265GlyVal: 2.265 ± 0.286
0.378GlyTrp: 0.378 ± 0.219
4.53GlyTyr: 4.53 ± 0.055
0.0GlyXaa: 0.0 ± 0.0
His
1.133HisAla: 1.133 ± 0.143
0.378HisCys: 0.378 ± 0.219
0.0HisAsp: 0.0 ± 0.0
1.133HisGlu: 1.133 ± 0.658
1.51HisPhe: 1.51 ± 0.153
0.755HisGly: 0.755 ± 0.077
0.378HisHis: 0.378 ± 0.219
1.51HisIle: 1.51 ± 0.362
0.378HisLys: 0.378 ± 0.219
1.51HisLeu: 1.51 ± 0.878
0.378HisMet: 0.378 ± 0.2
0.755HisAsn: 0.755 ± 0.077
1.51HisPro: 1.51 ± 0.153
0.755HisGln: 0.755 ± 0.439
0.378HisArg: 0.378 ± 0.219
1.51HisSer: 1.51 ± 0.362
0.0HisThr: 0.0 ± 0.0
2.643HisVal: 2.643 ± 1.536
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
6.795IleAla: 6.795 ± 0.857
0.755IleCys: 0.755 ± 0.077
2.643IleAsp: 2.643 ± 0.011
4.53IleGlu: 4.53 ± 0.46
1.888IlePhe: 1.888 ± 0.582
3.02IleGly: 3.02 ± 0.822
0.755IleHis: 0.755 ± 0.439
1.888IleIle: 1.888 ± 0.066
1.888IleLys: 1.888 ± 0.066
3.02IleLeu: 3.02 ± 0.209
1.51IleMet: 1.51 ± 0.362
3.02IleAsn: 3.02 ± 0.209
3.398IlePro: 3.398 ± 0.087
0.755IleGln: 0.755 ± 0.077
2.643IleArg: 2.643 ± 0.011
7.173IleSer: 7.173 ± 0.045
4.153IleThr: 4.153 ± 0.352
5.285IleVal: 5.285 ± 0.021
0.0IleTrp: 0.0 ± 0.0
0.755IleTyr: 0.755 ± 0.077
0.0IleXaa: 0.0 ± 0.0
Lys
1.888LysAla: 1.888 ± 0.066
1.133LysCys: 1.133 ± 0.143
5.663LysAsp: 5.663 ± 1.23
1.888LysGlu: 1.888 ± 0.582
3.398LysPhe: 3.398 ± 0.087
3.02LysGly: 3.02 ± 0.209
1.51LysHis: 1.51 ± 0.153
4.153LysIle: 4.153 ± 0.352
3.775LysLys: 3.775 ± 0.899
2.643LysLeu: 2.643 ± 0.011
0.755LysMet: 0.755 ± 0.592
4.53LysAsn: 4.53 ± 1.602
2.265LysPro: 2.265 ± 0.286
0.755LysGln: 0.755 ± 0.592
3.02LysArg: 3.02 ± 1.24
2.643LysSer: 2.643 ± 0.505
4.153LysThr: 4.153 ± 0.867
3.398LysVal: 3.398 ± 0.428
0.378LysTrp: 0.378 ± 0.219
3.398LysTyr: 3.398 ± 0.944
0.0LysXaa: 0.0 ± 0.0
Leu
3.775LeuAla: 3.775 ± 0.648
2.265LeuCys: 2.265 ± 0.286
1.51LeuAsp: 1.51 ± 0.153
3.775LeuGlu: 3.775 ± 0.383
4.908LeuPhe: 4.908 ± 0.791
7.173LeuGly: 7.173 ± 1.502
1.133LeuHis: 1.133 ± 0.658
3.775LeuIle: 3.775 ± 0.383
4.153LeuLys: 4.153 ± 0.867
3.02LeuLeu: 3.02 ± 0.209
1.51LeuMet: 1.51 ± 0.362
3.02LeuAsn: 3.02 ± 1.24
3.398LeuPro: 3.398 ± 0.428
1.888LeuGln: 1.888 ± 0.066
4.153LeuArg: 4.153 ± 0.352
7.55LeuSer: 7.55 ± 0.264
5.663LeuThr: 5.663 ± 0.833
3.02LeuVal: 3.02 ± 0.209
0.755LeuTrp: 0.755 ± 0.439
2.643LeuTyr: 2.643 ± 0.011
0.0LeuXaa: 0.0 ± 0.0
Met
3.02MetAla: 3.02 ± 0.822
0.0MetCys: 0.0 ± 0.0
3.02MetAsp: 3.02 ± 0.725
2.643MetGlu: 2.643 ± 0.505
1.133MetPhe: 1.133 ± 0.373
1.133MetGly: 1.133 ± 0.658
0.755MetHis: 0.755 ± 0.439
1.51MetIle: 1.51 ± 0.878
1.133MetLys: 1.133 ± 0.373
3.02MetLeu: 3.02 ± 0.725
1.51MetMet: 1.51 ± 0.153
0.755MetAsn: 0.755 ± 0.439
3.02MetPro: 3.02 ± 0.725
1.888MetGln: 1.888 ± 0.066
1.51MetArg: 1.51 ± 0.362
0.755MetSer: 0.755 ± 0.592
1.51MetThr: 1.51 ± 0.153
1.133MetVal: 1.133 ± 0.658
0.0MetTrp: 0.0 ± 0.0
2.643MetTyr: 2.643 ± 0.526
0.0MetXaa: 0.0 ± 0.0
Asn
5.663AsnAla: 5.663 ± 0.198
0.755AsnCys: 0.755 ± 0.439
2.643AsnAsp: 2.643 ± 0.526
3.398AsnGlu: 3.398 ± 0.428
3.775AsnPhe: 3.775 ± 0.383
3.398AsnGly: 3.398 ± 0.428
2.265AsnHis: 2.265 ± 0.286
2.265AsnIle: 2.265 ± 0.286
3.775AsnLys: 3.775 ± 0.132
4.53AsnLeu: 4.53 ± 0.055
1.51AsnMet: 1.51 ± 0.153
4.908AsnAsn: 4.908 ± 0.241
3.398AsnPro: 3.398 ± 0.603
1.51AsnGln: 1.51 ± 0.362
0.755AsnArg: 0.755 ± 0.439
3.775AsnSer: 3.775 ± 0.899
3.02AsnThr: 3.02 ± 0.307
4.153AsnVal: 4.153 ± 0.352
0.0AsnTrp: 0.0 ± 0.0
0.755AsnTyr: 0.755 ± 0.592
0.0AsnXaa: 0.0 ± 0.0
Pro
2.643ProAla: 2.643 ± 1.042
0.378ProCys: 0.378 ± 0.219
3.02ProAsp: 3.02 ± 1.854
1.888ProGlu: 1.888 ± 0.45
1.888ProPhe: 1.888 ± 0.965
2.643ProGly: 2.643 ± 0.526
0.755ProHis: 0.755 ± 0.439
4.153ProIle: 4.153 ± 0.164
3.02ProLys: 3.02 ± 0.307
5.285ProLeu: 5.285 ± 0.021
0.755ProMet: 0.755 ± 0.077
1.888ProAsn: 1.888 ± 0.965
1.133ProPro: 1.133 ± 0.143
2.265ProGln: 2.265 ± 0.746
0.755ProArg: 0.755 ± 0.077
3.398ProSer: 3.398 ± 0.944
2.265ProThr: 2.265 ± 0.746
5.285ProVal: 5.285 ± 0.021
0.378ProTrp: 0.378 ± 0.296
3.775ProTyr: 3.775 ± 1.415
0.0ProXaa: 0.0 ± 0.0
Gln
2.643GlnAla: 2.643 ± 0.505
0.755GlnCys: 0.755 ± 0.592
3.02GlnAsp: 3.02 ± 0.822
1.51GlnGlu: 1.51 ± 0.362
0.755GlnPhe: 0.755 ± 0.077
1.133GlnGly: 1.133 ± 0.143
0.378GlnHis: 0.378 ± 0.219
1.888GlnIle: 1.888 ± 0.066
1.51GlnLys: 1.51 ± 0.362
3.398GlnLeu: 3.398 ± 1.119
1.888GlnMet: 1.888 ± 0.066
1.888GlnAsn: 1.888 ± 0.066
1.888GlnPro: 1.888 ± 0.965
3.02GlnGln: 3.02 ± 0.209
0.755GlnArg: 0.755 ± 0.439
2.643GlnSer: 2.643 ± 1.042
1.133GlnThr: 1.133 ± 0.143
3.398GlnVal: 3.398 ± 0.428
0.755GlnTrp: 0.755 ± 0.439
0.755GlnTyr: 0.755 ± 0.439
0.0GlnXaa: 0.0 ± 0.0
Arg
1.888ArgAla: 1.888 ± 0.965
0.378ArgCys: 0.378 ± 0.219
2.265ArgAsp: 2.265 ± 0.801
2.643ArgGlu: 2.643 ± 1.021
4.908ArgPhe: 4.908 ± 0.241
2.643ArgGly: 2.643 ± 0.011
0.378ArgHis: 0.378 ± 0.219
3.398ArgIle: 3.398 ± 0.087
2.265ArgLys: 2.265 ± 0.286
2.265ArgLeu: 2.265 ± 0.286
2.265ArgMet: 2.265 ± 0.286
1.51ArgAsn: 1.51 ± 0.153
1.51ArgPro: 1.51 ± 0.153
2.265ArgGln: 2.265 ± 0.801
4.53ArgArg: 4.53 ± 2.118
2.643ArgSer: 2.643 ± 0.505
4.153ArgThr: 4.153 ± 0.867
3.398ArgVal: 3.398 ± 0.428
0.0ArgTrp: 0.0 ± 0.0
0.378ArgTyr: 0.378 ± 0.219
0.0ArgXaa: 0.0 ± 0.0
Ser
6.04SerAla: 6.04 ± 0.614
1.133SerCys: 1.133 ± 0.143
4.153SerAsp: 4.153 ± 0.68
4.908SerGlu: 4.908 ± 0.275
3.398SerPhe: 3.398 ± 0.944
4.153SerGly: 4.153 ± 0.164
0.755SerHis: 0.755 ± 0.077
3.398SerIle: 3.398 ± 0.603
3.398SerLys: 3.398 ± 0.428
6.04SerLeu: 6.04 ± 0.933
2.265SerMet: 2.265 ± 0.801
2.265SerAsn: 2.265 ± 0.286
3.398SerPro: 3.398 ± 1.634
2.643SerGln: 2.643 ± 0.011
3.02SerArg: 3.02 ± 0.822
6.418SerSer: 6.418 ± 0.122
5.285SerThr: 5.285 ± 0.021
7.173SerVal: 7.173 ± 1.502
0.755SerTrp: 0.755 ± 0.077
2.643SerTyr: 2.643 ± 1.558
0.0SerXaa: 0.0 ± 0.0
Thr
6.04ThrAla: 6.04 ± 1.129
2.265ThrCys: 2.265 ± 0.746
4.908ThrAsp: 4.908 ± 0.756
2.265ThrGlu: 2.265 ± 1.317
4.53ThrPhe: 4.53 ± 0.976
3.398ThrGly: 3.398 ± 0.944
1.51ThrHis: 1.51 ± 0.153
3.398ThrIle: 3.398 ± 1.975
4.53ThrLys: 4.53 ± 0.055
3.02ThrLeu: 3.02 ± 0.725
0.755ThrMet: 0.755 ± 0.439
3.02ThrAsn: 3.02 ± 0.307
1.51ThrPro: 1.51 ± 0.153
1.888ThrGln: 1.888 ± 0.45
2.643ThrArg: 2.643 ± 0.505
3.02ThrSer: 3.02 ± 1.338
5.285ThrThr: 5.285 ± 1.053
5.663ThrVal: 5.663 ± 1.349
1.51ThrTrp: 1.51 ± 0.669
3.02ThrTyr: 3.02 ± 0.822
0.0ThrXaa: 0.0 ± 0.0
Val
4.908ValAla: 4.908 ± 0.241
1.888ValCys: 1.888 ± 0.582
6.795ValAsp: 6.795 ± 0.857
3.398ValGlu: 3.398 ± 0.087
2.265ValPhe: 2.265 ± 0.286
2.643ValGly: 2.643 ± 1.042
1.133ValHis: 1.133 ± 0.658
3.775ValIle: 3.775 ± 0.132
1.51ValLys: 1.51 ± 0.362
3.02ValLeu: 3.02 ± 1.24
3.775ValMet: 3.775 ± 1.163
3.775ValAsn: 3.775 ± 0.648
3.775ValPro: 3.775 ± 1.415
2.643ValGln: 2.643 ± 0.526
3.775ValArg: 3.775 ± 0.648
4.53ValSer: 4.53 ± 0.571
5.663ValThr: 5.663 ± 0.317
3.398ValVal: 3.398 ± 0.428
0.755ValTrp: 0.755 ± 0.077
3.398ValTyr: 3.398 ± 1.119
0.0ValXaa: 0.0 ± 0.0
Trp
1.133TrpAla: 1.133 ± 0.373
0.755TrpCys: 0.755 ± 0.439
1.133TrpAsp: 1.133 ± 0.373
0.0TrpGlu: 0.0 ± 0.0
0.755TrpPhe: 0.755 ± 0.077
0.378TrpGly: 0.378 ± 0.219
0.378TrpHis: 0.378 ± 0.219
0.0TrpIle: 0.0 ± 0.0
1.133TrpLys: 1.133 ± 0.658
2.265TrpLeu: 2.265 ± 0.286
0.378TrpMet: 0.378 ± 0.219
1.51TrpAsn: 1.51 ± 0.362
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
1.51TrpSer: 1.51 ± 0.669
0.0TrpThr: 0.0 ± 0.0
0.378TrpVal: 0.378 ± 0.219
0.0TrpTrp: 0.0 ± 0.0
1.133TrpTyr: 1.133 ± 0.373
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.133TyrAla: 1.133 ± 0.373
1.133TyrCys: 1.133 ± 0.658
2.265TyrAsp: 2.265 ± 1.777
0.378TyrGlu: 0.378 ± 0.219
1.888TyrPhe: 1.888 ± 0.965
1.51TyrGly: 1.51 ± 0.669
0.0TyrHis: 0.0 ± 0.0
1.888TyrIle: 1.888 ± 0.965
2.643TyrLys: 2.643 ± 0.011
2.643TyrLeu: 2.643 ± 0.526
1.133TyrMet: 1.133 ± 0.287
6.04TyrAsn: 6.04 ± 1.129
1.888TyrPro: 1.888 ± 0.066
2.265TyrGln: 2.265 ± 0.286
1.888TyrArg: 1.888 ± 0.45
3.398TyrSer: 3.398 ± 1.634
4.53TyrThr: 4.53 ± 1.492
2.265TyrVal: 2.265 ± 0.286
0.755TyrTrp: 0.755 ± 0.439
1.51TyrTyr: 1.51 ± 0.669
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2650 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski