Amino acid dipepetide frequency for Pythium polare RNA virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
11.781AlaAla: 11.781 ± 5.938
2.079AlaCys: 2.079 ± 0.423
6.93AlaAsp: 6.93 ± 0.744
5.544AlaGlu: 5.544 ± 0.205
7.623AlaPhe: 7.623 ± 0.218
9.009AlaGly: 9.009 ± 3.835
2.079AlaHis: 2.079 ± 0.577
3.465AlaIle: 3.465 ± 0.628
2.772AlaLys: 2.772 ± 0.898
8.316AlaLeu: 8.316 ± 0.308
2.079AlaMet: 2.079 ± 1.578
2.772AlaAsn: 2.772 ± 0.103
3.465AlaPro: 3.465 ± 1.629
3.465AlaGln: 3.465 ± 0.628
6.93AlaArg: 6.93 ± 1.257
9.009AlaSer: 9.009 ± 0.834
2.772AlaThr: 2.772 ± 0.898
7.623AlaVal: 7.623 ± 0.782
2.079AlaTrp: 2.079 ± 1.578
0.693AlaTyr: 0.693 ± 0.475
0.0AlaXaa: 0.0 ± 0.0
Cys
0.693CysAla: 0.693 ± 0.475
2.079CysCys: 2.079 ± 1.424
2.079CysAsp: 2.079 ± 1.424
2.772CysGlu: 2.772 ± 0.898
0.693CysPhe: 0.693 ± 0.475
2.079CysGly: 2.079 ± 0.423
0.693CysHis: 0.693 ± 0.475
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
2.079CysLeu: 2.079 ± 0.423
1.386CysMet: 1.386 ± 0.949
0.693CysAsn: 0.693 ± 0.475
1.386CysPro: 1.386 ± 1.052
0.0CysGln: 0.0 ± 0.0
1.386CysArg: 1.386 ± 0.051
2.772CysSer: 2.772 ± 0.898
1.386CysThr: 1.386 ± 0.949
1.386CysVal: 1.386 ± 0.051
1.386CysTrp: 1.386 ± 0.051
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
7.623AspAla: 7.623 ± 1.783
1.386AspCys: 1.386 ± 0.949
0.693AspAsp: 0.693 ± 0.475
3.465AspGlu: 3.465 ± 1.372
1.386AspPhe: 1.386 ± 1.052
5.544AspGly: 5.544 ± 1.206
1.386AspHis: 1.386 ± 0.051
1.386AspIle: 1.386 ± 0.051
2.079AspLys: 2.079 ± 1.424
5.544AspLeu: 5.544 ± 0.205
0.693AspMet: 0.693 ± 0.526
1.386AspAsn: 1.386 ± 0.051
1.386AspPro: 1.386 ± 0.949
4.158AspGln: 4.158 ± 1.154
2.079AspArg: 2.079 ± 0.423
4.851AspSer: 4.851 ± 0.321
3.465AspThr: 3.465 ± 1.372
5.544AspVal: 5.544 ± 1.796
1.386AspTrp: 1.386 ± 0.949
0.693AspTyr: 0.693 ± 0.475
0.0AspXaa: 0.0 ± 0.0
Glu
3.465GluAla: 3.465 ± 0.372
1.386GluCys: 1.386 ± 0.949
2.079GluAsp: 2.079 ± 0.423
4.158GluGlu: 4.158 ± 1.154
2.772GluPhe: 2.772 ± 1.898
3.465GluGly: 3.465 ± 2.629
0.0GluHis: 0.0 ± 0.0
0.693GluIle: 0.693 ± 0.526
2.079GluLys: 2.079 ± 0.577
5.544GluLeu: 5.544 ± 2.796
1.386GluMet: 1.386 ± 0.051
0.0GluAsn: 0.0 ± 0.0
0.693GluPro: 0.693 ± 0.475
1.386GluGln: 1.386 ± 1.052
6.237GluArg: 6.237 ± 0.269
2.079GluSer: 2.079 ± 0.577
0.0GluThr: 0.0 ± 0.0
6.93GluVal: 6.93 ± 1.744
2.079GluTrp: 2.079 ± 0.423
0.693GluTyr: 0.693 ± 0.475
0.0GluXaa: 0.0 ± 0.0
Phe
2.772PheAla: 2.772 ± 0.898
0.693PheCys: 0.693 ± 0.475
4.158PheAsp: 4.158 ± 1.154
2.772PheGlu: 2.772 ± 1.103
3.465PhePhe: 3.465 ± 1.629
4.158PheGly: 4.158 ± 0.846
0.0PheHis: 0.0 ± 0.0
0.0PheIle: 0.0 ± 0.0
1.386PheLys: 1.386 ± 0.949
4.158PheLeu: 4.158 ± 0.154
0.693PheMet: 0.693 ± 0.354
0.693PheAsn: 0.693 ± 0.475
1.386PhePro: 1.386 ± 0.051
0.0PheGln: 0.0 ± 0.0
6.237PheArg: 6.237 ± 1.27
1.386PheSer: 1.386 ± 0.949
2.079PheThr: 2.079 ± 0.577
2.772PheVal: 2.772 ± 2.103
1.386PheTrp: 1.386 ± 1.052
0.693PheTyr: 0.693 ± 0.475
0.0PheXaa: 0.0 ± 0.0
Gly
11.781GlyAla: 11.781 ± 0.936
2.079GlyCys: 2.079 ± 0.423
4.851GlyAsp: 4.851 ± 0.68
1.386GlyGlu: 1.386 ± 0.949
2.772GlyPhe: 2.772 ± 1.103
8.316GlyGly: 8.316 ± 1.308
2.772GlyHis: 2.772 ± 0.898
2.079GlyIle: 2.079 ± 0.577
4.851GlyLys: 4.851 ± 2.321
11.781GlyLeu: 11.781 ± 1.065
2.772GlyMet: 2.772 ± 1.898
2.772GlyAsn: 2.772 ± 0.103
4.158GlyPro: 4.158 ± 2.155
0.0GlyGln: 0.0 ± 0.0
8.316GlyArg: 8.316 ± 0.308
13.167GlySer: 13.167 ± 2.988
3.465GlyThr: 3.465 ± 0.628
9.009GlyVal: 9.009 ± 1.834
2.079GlyTrp: 2.079 ± 0.577
2.772GlyTyr: 2.772 ± 0.898
0.0GlyXaa: 0.0 ± 0.0
His
1.386HisAla: 1.386 ± 0.949
0.0HisCys: 0.0 ± 0.0
2.079HisAsp: 2.079 ± 0.577
0.693HisGlu: 0.693 ± 0.475
0.0HisPhe: 0.0 ± 0.0
1.386HisGly: 1.386 ± 0.051
0.0HisHis: 0.0 ± 0.0
0.693HisIle: 0.693 ± 0.526
0.693HisLys: 0.693 ± 0.475
2.772HisLeu: 2.772 ± 2.103
0.693HisMet: 0.693 ± 0.475
0.693HisAsn: 0.693 ± 0.526
2.079HisPro: 2.079 ± 0.577
0.0HisGln: 0.0 ± 0.0
0.693HisArg: 0.693 ± 0.526
0.693HisSer: 0.693 ± 0.475
0.0HisThr: 0.0 ± 0.0
3.465HisVal: 3.465 ± 1.372
0.0HisTrp: 0.0 ± 0.0
0.693HisTyr: 0.693 ± 0.526
0.0HisXaa: 0.0 ± 0.0
Ile
3.465IleAla: 3.465 ± 1.629
0.0IleCys: 0.0 ± 0.0
2.079IleAsp: 2.079 ± 1.424
2.079IleGlu: 2.079 ± 0.423
0.0IlePhe: 0.0 ± 0.0
1.386IleGly: 1.386 ± 0.051
0.693IleHis: 0.693 ± 0.526
1.386IleIle: 1.386 ± 0.949
0.0IleLys: 0.0 ± 0.0
3.465IleLeu: 3.465 ± 0.372
0.0IleMet: 0.0 ± 0.0
0.0IleAsn: 0.0 ± 0.0
2.079IlePro: 2.079 ± 0.577
0.0IleGln: 0.0 ± 0.0
2.772IleArg: 2.772 ± 0.103
2.772IleSer: 2.772 ± 2.103
0.693IleThr: 0.693 ± 0.526
2.079IleVal: 2.079 ± 0.423
1.386IleTrp: 1.386 ± 0.949
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
2.079LysAla: 2.079 ± 1.424
1.386LysCys: 1.386 ± 0.949
1.386LysAsp: 1.386 ± 0.949
2.772LysGlu: 2.772 ± 1.898
2.079LysPhe: 2.079 ± 0.577
2.079LysGly: 2.079 ± 0.423
0.693LysHis: 0.693 ± 0.475
2.079LysIle: 2.079 ± 0.423
0.0LysLys: 0.0 ± 0.0
2.079LysLeu: 2.079 ± 1.424
0.0LysMet: 0.0 ± 0.0
0.693LysAsn: 0.693 ± 0.526
2.079LysPro: 2.079 ± 0.423
0.0LysGln: 0.0 ± 0.0
2.772LysArg: 2.772 ± 0.898
1.386LysSer: 1.386 ± 1.052
3.465LysThr: 3.465 ± 1.372
0.693LysVal: 0.693 ± 0.526
2.079LysTrp: 2.079 ± 1.424
0.0LysTyr: 0.0 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
9.009LeuAla: 9.009 ± 3.835
1.386LeuCys: 1.386 ± 0.949
4.851LeuAsp: 4.851 ± 0.68
3.465LeuGlu: 3.465 ± 0.372
1.386LeuPhe: 1.386 ± 0.949
15.939LeuGly: 15.939 ± 2.911
0.693LeuHis: 0.693 ± 0.475
1.386LeuIle: 1.386 ± 0.051
2.079LeuLys: 2.079 ± 0.423
4.851LeuLeu: 4.851 ± 1.68
0.0LeuMet: 0.0 ± 0.0
6.93LeuAsn: 6.93 ± 2.745
5.544LeuPro: 5.544 ± 1.206
1.386LeuGln: 1.386 ± 1.052
6.237LeuArg: 6.237 ± 2.27
9.702LeuSer: 9.702 ± 0.359
3.465LeuThr: 3.465 ± 0.628
8.316LeuVal: 8.316 ± 3.694
2.772LeuTrp: 2.772 ± 0.103
2.079LeuTyr: 2.079 ± 0.423
0.0LeuXaa: 0.0 ± 0.0
Met
3.465MetAla: 3.465 ± 0.372
0.0MetCys: 0.0 ± 0.0
2.079MetAsp: 2.079 ± 0.577
0.693MetGlu: 0.693 ± 0.475
0.0MetPhe: 0.0 ± 0.0
2.079MetGly: 2.079 ± 1.424
0.0MetHis: 0.0 ± 0.0
0.693MetIle: 0.693 ± 0.526
0.693MetLys: 0.693 ± 0.475
2.772MetLeu: 2.772 ± 0.898
0.0MetMet: 0.0 ± 0.0
0.693MetAsn: 0.693 ± 0.526
1.386MetPro: 1.386 ± 0.051
0.0MetGln: 0.0 ± 0.0
1.386MetArg: 1.386 ± 0.949
1.386MetSer: 1.386 ± 0.051
1.386MetThr: 1.386 ± 1.052
2.079MetVal: 2.079 ± 0.423
2.079MetTrp: 2.079 ± 0.423
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.079AsnAla: 2.079 ± 0.423
0.693AsnCys: 0.693 ± 0.526
0.693AsnAsp: 0.693 ± 0.526
0.0AsnGlu: 0.0 ± 0.0
1.386AsnPhe: 1.386 ± 0.051
1.386AsnGly: 1.386 ± 0.051
0.0AsnHis: 0.0 ± 0.0
2.079AsnIle: 2.079 ± 0.423
0.693AsnLys: 0.693 ± 0.475
2.079AsnLeu: 2.079 ± 0.423
0.0AsnMet: 0.0 ± 0.0
0.0AsnAsn: 0.0 ± 0.0
1.386AsnPro: 1.386 ± 1.052
0.693AsnGln: 0.693 ± 0.475
3.465AsnArg: 3.465 ± 2.373
2.079AsnSer: 2.079 ± 0.577
0.0AsnThr: 0.0 ± 0.0
3.465AsnVal: 3.465 ± 0.628
2.772AsnTrp: 2.772 ± 0.103
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
5.544ProAla: 5.544 ± 2.206
0.0ProCys: 0.0 ± 0.0
2.079ProAsp: 2.079 ± 0.577
2.772ProGlu: 2.772 ± 0.103
2.079ProPhe: 2.079 ± 0.577
3.465ProGly: 3.465 ± 0.628
1.386ProHis: 1.386 ± 1.052
0.0ProIle: 0.0 ± 0.0
0.693ProLys: 0.693 ± 0.475
4.851ProLeu: 4.851 ± 1.321
0.0ProMet: 0.0 ± 0.0
0.0ProAsn: 0.0 ± 0.0
0.0ProPro: 0.0 ± 0.0
1.386ProGln: 1.386 ± 1.052
0.693ProArg: 0.693 ± 0.526
4.158ProSer: 4.158 ± 2.155
1.386ProThr: 1.386 ± 1.052
7.623ProVal: 7.623 ± 1.218
3.465ProTrp: 3.465 ± 0.628
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
2.772GlnAla: 2.772 ± 2.103
0.0GlnCys: 0.0 ± 0.0
0.0GlnAsp: 0.0 ± 0.0
1.386GlnGlu: 1.386 ± 0.051
0.693GlnPhe: 0.693 ± 0.526
2.772GlnGly: 2.772 ± 1.103
0.0GlnHis: 0.0 ± 0.0
0.693GlnIle: 0.693 ± 0.475
0.693GlnLys: 0.693 ± 0.526
0.693GlnLeu: 0.693 ± 0.526
0.693GlnMet: 0.693 ± 0.526
0.0GlnAsn: 0.0 ± 0.0
2.079GlnPro: 2.079 ± 0.577
1.386GlnGln: 1.386 ± 0.051
3.465GlnArg: 3.465 ± 0.628
3.465GlnSer: 3.465 ± 1.629
0.0GlnThr: 0.0 ± 0.0
2.079GlnVal: 2.079 ± 0.577
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
6.93ArgAla: 6.93 ± 1.744
2.772ArgCys: 2.772 ± 0.898
5.544ArgAsp: 5.544 ± 1.796
0.693ArgGlu: 0.693 ± 0.526
1.386ArgPhe: 1.386 ± 0.949
13.86ArgGly: 13.86 ± 0.487
2.079ArgHis: 2.079 ± 0.577
2.772ArgIle: 2.772 ± 0.898
2.772ArgLys: 2.772 ± 0.898
10.395ArgLeu: 10.395 ± 3.117
6.237ArgMet: 6.237 ± 0.731
1.386ArgAsn: 1.386 ± 0.949
0.693ArgPro: 0.693 ± 0.475
1.386ArgGln: 1.386 ± 1.052
7.623ArgArg: 7.623 ± 2.219
6.237ArgSer: 6.237 ± 2.732
2.079ArgThr: 2.079 ± 0.423
7.623ArgVal: 7.623 ± 0.218
2.079ArgTrp: 2.079 ± 0.423
2.079ArgTyr: 2.079 ± 0.423
0.0ArgXaa: 0.0 ± 0.0
Ser
8.316SerAla: 8.316 ± 2.309
2.772SerCys: 2.772 ± 0.103
4.851SerAsp: 4.851 ± 1.321
4.158SerGlu: 4.158 ± 0.154
4.851SerPhe: 4.851 ± 0.68
13.167SerGly: 13.167 ± 1.013
0.693SerHis: 0.693 ± 0.526
2.079SerIle: 2.079 ± 0.577
2.079SerLys: 2.079 ± 0.577
4.851SerLeu: 4.851 ± 1.68
0.693SerMet: 0.693 ± 0.475
0.0SerAsn: 0.0 ± 0.0
4.851SerPro: 4.851 ± 0.68
1.386SerGln: 1.386 ± 1.052
5.544SerArg: 5.544 ± 0.205
5.544SerSer: 5.544 ± 0.205
4.158SerThr: 4.158 ± 2.155
7.623SerVal: 7.623 ± 1.783
4.851SerTrp: 4.851 ± 0.68
3.465SerTyr: 3.465 ± 0.372
0.0SerXaa: 0.0 ± 0.0
Thr
4.158ThrAla: 4.158 ± 0.154
0.0ThrCys: 0.0 ± 0.0
0.0ThrAsp: 0.0 ± 0.0
2.772ThrGlu: 2.772 ± 0.103
0.693ThrPhe: 0.693 ± 0.526
1.386ThrGly: 1.386 ± 0.051
0.693ThrHis: 0.693 ± 0.526
2.079ThrIle: 2.079 ± 0.423
2.772ThrLys: 2.772 ± 0.898
4.158ThrLeu: 4.158 ± 1.154
1.386ThrMet: 1.386 ± 0.051
2.079ThrAsn: 2.079 ± 1.578
1.386ThrPro: 1.386 ± 0.051
1.386ThrGln: 1.386 ± 0.051
4.158ThrArg: 4.158 ± 0.154
3.465ThrSer: 3.465 ± 0.372
1.386ThrThr: 1.386 ± 0.051
3.465ThrVal: 3.465 ± 0.372
0.693ThrTrp: 0.693 ± 0.475
0.693ThrTyr: 0.693 ± 0.475
0.0ThrXaa: 0.0 ± 0.0
Val
6.93ValAla: 6.93 ± 1.257
4.158ValCys: 4.158 ± 0.846
5.544ValAsp: 5.544 ± 0.205
3.465ValGlu: 3.465 ± 0.372
6.237ValPhe: 6.237 ± 0.731
6.237ValGly: 6.237 ± 0.269
4.851ValHis: 4.851 ± 0.321
1.386ValIle: 1.386 ± 0.051
2.772ValLys: 2.772 ± 0.898
6.93ValLeu: 6.93 ± 1.744
2.079ValMet: 2.079 ± 1.677
2.772ValAsn: 2.772 ± 0.103
4.851ValPro: 4.851 ± 0.321
1.386ValGln: 1.386 ± 1.052
11.088ValArg: 11.088 ± 0.59
8.316ValSer: 8.316 ± 2.693
3.465ValThr: 3.465 ± 1.629
4.851ValVal: 4.851 ± 1.321
0.693ValTrp: 0.693 ± 0.526
1.386ValTyr: 1.386 ± 1.052
0.0ValXaa: 0.0 ± 0.0
Trp
4.851TrpAla: 4.851 ± 0.68
2.079TrpCys: 2.079 ± 0.423
1.386TrpAsp: 1.386 ± 0.051
1.386TrpGlu: 1.386 ± 1.052
0.0TrpPhe: 0.0 ± 0.0
2.079TrpGly: 2.079 ± 0.577
0.0TrpHis: 0.0 ± 0.0
1.386TrpIle: 1.386 ± 1.052
0.693TrpLys: 0.693 ± 0.475
2.772TrpLeu: 2.772 ± 0.103
1.386TrpMet: 1.386 ± 0.949
1.386TrpAsn: 1.386 ± 0.051
0.693TrpPro: 0.693 ± 0.526
2.079TrpGln: 2.079 ± 0.577
2.772TrpArg: 2.772 ± 0.898
2.079TrpSer: 2.079 ± 0.577
3.465TrpThr: 3.465 ± 2.373
3.465TrpVal: 3.465 ± 0.372
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.386TyrAla: 1.386 ± 0.051
0.0TyrCys: 0.0 ± 0.0
2.772TyrAsp: 2.772 ± 0.898
0.693TyrGlu: 0.693 ± 0.475
1.386TyrPhe: 1.386 ± 0.949
1.386TyrGly: 1.386 ± 1.052
0.0TyrHis: 0.0 ± 0.0
0.0TyrIle: 0.0 ± 0.0
0.0TyrLys: 0.0 ± 0.0
1.386TyrLeu: 1.386 ± 0.051
0.0TyrMet: 0.0 ± 0.0
0.0TyrAsn: 0.0 ± 0.0
0.0TyrPro: 0.0 ± 0.0
1.386TyrGln: 1.386 ± 0.051
2.772TyrArg: 2.772 ± 1.898
1.386TyrSer: 1.386 ± 0.051
0.693TyrThr: 0.693 ± 0.526
0.0TyrVal: 0.0 ± 0.0
0.693TyrTrp: 0.693 ± 0.475
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1444 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski