Amino acid dipepetide frequency for Hubei sobemo-like virus 48

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.596AlaAla: 5.596 ± 2.657
0.799AlaCys: 0.799 ± 0.598
3.197AlaAsp: 3.197 ± 0.49
2.398AlaGlu: 2.398 ± 0.13
3.197AlaPhe: 3.197 ± 1.773
4.796AlaGly: 4.796 ± 2.136
0.0AlaHis: 0.0 ± 0.0
3.197AlaIle: 3.197 ± 1.426
4.796AlaLys: 4.796 ± 1.105
5.596AlaLeu: 5.596 ± 3.337
1.599AlaMet: 1.599 ± 1.533
2.398AlaAsn: 2.398 ± 1.019
3.197AlaPro: 3.197 ± 0.884
2.398AlaGln: 2.398 ± 1.019
4.796AlaArg: 4.796 ± 0.982
7.194AlaSer: 7.194 ± 1.853
3.997AlaThr: 3.997 ± 2.17
7.194AlaVal: 7.194 ± 3.044
2.398AlaTrp: 2.398 ± 0.13
2.398AlaTyr: 2.398 ± 1.327
0.799AlaXaa: 0.799 ± 0.598
Cys
0.799CysAla: 0.799 ± 0.655
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.799CysGlu: 0.799 ± 0.655
0.0CysPhe: 0.0 ± 0.0
1.599CysGly: 1.599 ± 0.675
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
0.799CysLeu: 0.799 ± 0.655
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
2.398CysSer: 2.398 ± 1.165
0.799CysThr: 0.799 ± 0.655
2.398CysVal: 2.398 ± 2.299
0.0CysTrp: 0.0 ± 0.0
0.799CysTyr: 0.799 ± 0.766
0.0CysXaa: 0.0 ± 0.0
Asp
3.197AspAla: 3.197 ± 1.35
0.0AspCys: 0.0 ± 0.0
3.997AspAsp: 3.997 ± 2.792
1.599AspGlu: 1.599 ± 1.196
3.997AspPhe: 3.997 ± 2.793
7.994AspGly: 7.994 ± 1.7
4.796AspHis: 4.796 ± 1.963
2.398AspIle: 2.398 ± 0.13
1.599AspLys: 1.599 ± 0.713
6.395AspLeu: 6.395 ± 0.955
0.799AspMet: 0.799 ± 0.766
0.0AspAsn: 0.0 ± 0.0
0.799AspPro: 0.799 ± 0.655
1.599AspGln: 1.599 ± 0.654
2.398AspArg: 2.398 ± 1.165
3.997AspSer: 3.997 ± 1.649
2.398AspThr: 2.398 ± 1.135
5.596AspVal: 5.596 ± 1.2
5.596AspTrp: 5.596 ± 2.597
3.997AspTyr: 3.997 ± 1.085
0.0AspXaa: 0.0 ± 0.0
Glu
4.796GluAla: 4.796 ± 1.682
0.799GluCys: 0.799 ± 0.766
5.596GluAsp: 5.596 ± 0.692
3.197GluGlu: 3.197 ± 0.884
3.997GluPhe: 3.997 ± 0.718
2.398GluGly: 2.398 ± 1.315
1.599GluHis: 1.599 ± 1.533
3.197GluIle: 3.197 ± 1.528
1.599GluLys: 1.599 ± 1.311
2.398GluLeu: 2.398 ± 1.165
1.599GluMet: 1.599 ± 0.654
1.599GluAsn: 1.599 ± 0.675
3.197GluPro: 3.197 ± 1.426
0.799GluGln: 0.799 ± 0.766
0.799GluArg: 0.799 ± 0.655
3.997GluSer: 3.997 ± 2.407
0.799GluThr: 0.799 ± 0.598
3.997GluVal: 3.997 ± 1.667
1.599GluTrp: 1.599 ± 0.713
2.398GluTyr: 2.398 ± 1.315
0.0GluXaa: 0.0 ± 0.0
Phe
2.398PheAla: 2.398 ± 1.793
0.799PheCys: 0.799 ± 0.655
5.596PheAsp: 5.596 ± 1.004
1.599PheGlu: 1.599 ± 1.196
0.799PhePhe: 0.799 ± 0.655
2.398PheGly: 2.398 ± 1.165
0.0PheHis: 0.0 ± 0.0
1.599PheIle: 1.599 ± 0.675
1.599PheLys: 1.599 ± 0.654
2.398PheLeu: 2.398 ± 0.13
0.0PheMet: 0.0 ± 0.0
1.599PheAsn: 1.599 ± 0.654
0.799PhePro: 0.799 ± 0.598
0.799PheGln: 0.799 ± 0.598
2.398PheArg: 2.398 ± 0.13
3.197PheSer: 3.197 ± 2.047
0.799PheThr: 0.799 ± 0.766
3.197PheVal: 3.197 ± 0.49
0.0PheTrp: 0.0 ± 0.0
1.599PheTyr: 1.599 ± 1.196
0.0PheXaa: 0.0 ± 0.0
Gly
4.796GlyAla: 4.796 ± 2.33
1.599GlyCys: 1.599 ± 0.713
3.997GlyAsp: 3.997 ± 1.085
2.398GlyGlu: 2.398 ± 1.165
3.997GlyPhe: 3.997 ± 1.667
7.194GlyGly: 7.194 ± 0.808
2.398GlyHis: 2.398 ± 1.327
1.599GlyIle: 1.599 ± 0.675
5.596GlyLys: 5.596 ± 0.396
5.596GlyLeu: 5.596 ± 1.004
2.398GlyMet: 2.398 ± 0.13
0.799GlyAsn: 0.799 ± 0.655
5.596GlyPro: 5.596 ± 1.474
1.599GlyGln: 1.599 ± 0.654
7.194GlyArg: 7.194 ± 1.293
5.596GlySer: 5.596 ± 2.403
4.796GlyThr: 4.796 ± 0.26
7.994GlyVal: 7.994 ± 2.62
0.799GlyTrp: 0.799 ± 0.766
3.197GlyTyr: 3.197 ± 1.308
0.0GlyXaa: 0.0 ± 0.0
His
0.799HisAla: 0.799 ± 0.766
0.799HisCys: 0.799 ± 0.766
3.997HisAsp: 3.997 ± 0.549
0.799HisGlu: 0.799 ± 0.766
0.0HisPhe: 0.0 ± 0.0
2.398HisGly: 2.398 ± 0.13
0.799HisHis: 0.799 ± 0.766
0.0HisIle: 0.0 ± 0.0
3.197HisLys: 3.197 ± 1.426
1.599HisLeu: 1.599 ± 1.311
2.398HisMet: 2.398 ± 2.299
0.0HisAsn: 0.0 ± 0.0
2.398HisPro: 2.398 ± 2.299
0.799HisGln: 0.799 ± 0.655
0.799HisArg: 0.799 ± 0.766
0.799HisSer: 0.799 ± 0.598
1.599HisThr: 1.599 ± 1.533
3.197HisVal: 3.197 ± 0.49
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
0.799IleAla: 0.799 ± 0.598
0.0IleCys: 0.0 ± 0.0
0.799IleAsp: 0.799 ± 0.598
3.197IleGlu: 3.197 ± 1.308
1.599IlePhe: 1.599 ± 1.196
3.197IleGly: 3.197 ± 1.773
0.799IleHis: 0.799 ± 0.655
2.398IleIle: 2.398 ± 1.019
3.997IleLys: 3.997 ± 2.085
4.796IleLeu: 4.796 ± 1.682
1.599IleMet: 1.599 ± 1.533
1.599IleAsn: 1.599 ± 1.196
3.197IlePro: 3.197 ± 1.426
0.799IleGln: 0.799 ± 0.598
4.796IleArg: 4.796 ± 0.26
3.997IleSer: 3.997 ± 1.649
0.0IleThr: 0.0 ± 0.0
3.197IleVal: 3.197 ± 0.661
2.398IleTrp: 2.398 ± 0.13
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
3.997LysAla: 3.997 ± 0.549
1.599LysCys: 1.599 ± 0.654
5.596LysAsp: 5.596 ± 1.732
2.398LysGlu: 2.398 ± 0.13
2.398LysPhe: 2.398 ± 1.165
3.197LysGly: 3.197 ± 1.773
1.599LysHis: 1.599 ± 1.533
3.197LysIle: 3.197 ± 1.773
6.395LysLys: 6.395 ± 1.323
6.395LysLeu: 6.395 ± 1.323
2.398LysMet: 2.398 ± 0.13
1.599LysAsn: 1.599 ± 1.311
1.599LysPro: 1.599 ± 1.196
2.398LysGln: 2.398 ± 1.019
3.997LysArg: 3.997 ± 0.549
3.197LysSer: 3.197 ± 2.044
2.398LysThr: 2.398 ± 0.13
1.599LysVal: 1.599 ± 1.196
3.197LysTrp: 3.197 ± 1.426
0.799LysTyr: 0.799 ± 0.655
0.0LysXaa: 0.0 ± 0.0
Leu
3.197LeuAla: 3.197 ± 2.047
0.0LeuCys: 0.0 ± 0.0
7.194LeuAsp: 7.194 ± 1.587
6.395LeuGlu: 6.395 ± 0.955
1.599LeuPhe: 1.599 ± 0.675
5.596LeuGly: 5.596 ± 2.657
0.799LeuHis: 0.799 ± 0.598
2.398LeuIle: 2.398 ± 1.327
6.395LeuLys: 6.395 ± 1.691
8.793LeuLeu: 8.793 ± 2.594
2.398LeuMet: 2.398 ± 0.444
0.0LeuAsn: 0.0 ± 0.0
9.592LeuPro: 9.592 ± 1.47
5.596LeuGln: 5.596 ± 1.458
3.997LeuArg: 3.997 ± 0.832
9.592LeuSer: 9.592 ± 1.026
1.599LeuThr: 1.599 ± 0.654
7.194LeuVal: 7.194 ± 1.969
1.599LeuTrp: 1.599 ± 0.713
1.599LeuTyr: 1.599 ± 0.675
0.0LeuXaa: 0.0 ± 0.0
Met
3.197MetAla: 3.197 ± 2.047
0.0MetCys: 0.0 ± 0.0
1.599MetAsp: 1.599 ± 0.713
2.398MetGlu: 2.398 ± 2.299
0.799MetPhe: 0.799 ± 0.766
2.398MetGly: 2.398 ± 0.13
3.197MetHis: 3.197 ± 0.884
0.0MetIle: 0.0 ± 0.0
1.599MetLys: 1.599 ± 1.533
2.398MetLeu: 2.398 ± 1.135
0.799MetMet: 0.799 ± 0.766
0.799MetAsn: 0.799 ± 0.766
1.599MetPro: 1.599 ± 0.675
1.599MetGln: 1.599 ± 1.533
2.398MetArg: 2.398 ± 0.13
3.997MetSer: 3.997 ± 1.31
1.599MetThr: 1.599 ± 1.196
1.599MetVal: 1.599 ± 0.654
0.0MetTrp: 0.0 ± 0.0
1.599MetTyr: 1.599 ± 1.533
0.0MetXaa: 0.0 ± 0.0
Asn
1.599AsnAla: 1.599 ± 1.196
0.0AsnCys: 0.0 ± 0.0
0.799AsnAsp: 0.799 ± 0.766
0.799AsnGlu: 0.799 ± 0.598
1.599AsnPhe: 1.599 ± 0.654
3.197AsnGly: 3.197 ± 2.047
0.799AsnHis: 0.799 ± 0.655
0.799AsnIle: 0.799 ± 0.766
0.0AsnLys: 0.0 ± 0.0
2.398AsnLeu: 2.398 ± 1.165
0.799AsnMet: 0.799 ± 0.766
0.0AsnAsn: 0.0 ± 0.0
1.599AsnPro: 1.599 ± 1.196
0.0AsnGln: 0.0 ± 0.0
1.599AsnArg: 1.599 ± 0.675
3.197AsnSer: 3.197 ± 1.308
0.799AsnThr: 0.799 ± 0.766
1.599AsnVal: 1.599 ± 0.675
0.799AsnTrp: 0.799 ± 0.655
0.799AsnTyr: 0.799 ± 0.598
0.0AsnXaa: 0.0 ± 0.0
Pro
5.596ProAla: 5.596 ± 2.657
0.799ProCys: 0.799 ± 0.655
3.997ProAsp: 3.997 ± 1.778
2.398ProGlu: 2.398 ± 1.165
0.0ProPhe: 0.0 ± 0.0
5.596ProGly: 5.596 ± 0.692
1.599ProHis: 1.599 ± 1.533
1.599ProIle: 1.599 ± 1.196
2.398ProLys: 2.398 ± 0.13
3.997ProLeu: 3.997 ± 0.718
1.599ProMet: 1.599 ± 1.533
0.0ProAsn: 0.0 ± 0.0
0.799ProPro: 0.799 ± 0.598
1.599ProGln: 1.599 ± 1.196
3.997ProArg: 3.997 ± 0.549
4.796ProSer: 4.796 ± 1.682
2.398ProThr: 2.398 ± 0.13
4.796ProVal: 4.796 ± 2.025
0.799ProTrp: 0.799 ± 0.598
2.398ProTyr: 2.398 ± 2.299
0.0ProXaa: 0.0 ± 0.0
Gln
5.596GlnAla: 5.596 ± 0.396
0.799GlnCys: 0.799 ± 0.766
0.799GlnAsp: 0.799 ± 0.598
2.398GlnGlu: 2.398 ± 1.135
2.398GlnPhe: 2.398 ± 1.068
0.799GlnGly: 0.799 ± 0.598
0.799GlnHis: 0.799 ± 0.766
2.398GlnIle: 2.398 ± 1.068
0.799GlnLys: 0.799 ± 0.655
3.997GlnLeu: 3.997 ± 1.622
0.799GlnMet: 0.799 ± 0.655
0.799GlnAsn: 0.799 ± 0.655
2.398GlnPro: 2.398 ± 1.068
2.398GlnGln: 2.398 ± 1.165
2.398GlnArg: 2.398 ± 1.068
3.997GlnSer: 3.997 ± 0.718
0.799GlnThr: 0.799 ± 0.766
3.197GlnVal: 3.197 ± 0.49
0.799GlnTrp: 0.799 ± 0.598
0.799GlnTyr: 0.799 ± 0.766
0.0GlnXaa: 0.0 ± 0.0
Arg
1.599ArgAla: 1.599 ± 0.654
0.0ArgCys: 0.0 ± 0.0
0.799ArgAsp: 0.799 ± 0.655
3.197ArgGlu: 3.197 ± 1.426
3.197ArgPhe: 3.197 ± 0.49
3.197ArgGly: 3.197 ± 1.528
0.799ArgHis: 0.799 ± 0.598
0.799ArgIle: 0.799 ± 0.655
5.596ArgLys: 5.596 ± 2.296
6.395ArgLeu: 6.395 ± 2.117
4.796ArgMet: 4.796 ± 1.402
1.599ArgAsn: 1.599 ± 1.196
0.799ArgPro: 0.799 ± 0.598
3.197ArgGln: 3.197 ± 1.711
0.799ArgArg: 0.799 ± 0.766
4.796ArgSer: 4.796 ± 1.682
5.596ArgThr: 5.596 ± 1.474
4.796ArgVal: 4.796 ± 1.105
1.599ArgTrp: 1.599 ± 1.533
3.997ArgTyr: 3.997 ± 2.792
0.0ArgXaa: 0.0 ± 0.0
Ser
7.994SerAla: 7.994 ± 2.527
0.0SerCys: 0.0 ± 0.0
4.796SerAsp: 4.796 ± 0.982
4.796SerGlu: 4.796 ± 0.26
0.799SerPhe: 0.799 ± 0.598
7.994SerGly: 7.994 ± 3.624
0.0SerHis: 0.0 ± 0.0
4.796SerIle: 4.796 ± 1.682
6.395SerLys: 6.395 ± 2.363
7.994SerLeu: 7.994 ± 0.327
1.599SerMet: 1.599 ± 1.133
2.398SerAsn: 2.398 ± 0.13
5.596SerPro: 5.596 ± 0.396
7.194SerGln: 7.194 ± 2.267
4.796SerArg: 4.796 ± 0.938
7.194SerSer: 7.194 ± 1.575
2.398SerThr: 2.398 ± 0.13
5.596SerVal: 5.596 ± 1.004
2.398SerTrp: 2.398 ± 0.13
2.398SerTyr: 2.398 ± 1.135
0.0SerXaa: 0.0 ± 0.0
Thr
2.398ThrAla: 2.398 ± 0.13
0.799ThrCys: 0.799 ± 0.766
1.599ThrAsp: 1.599 ± 0.713
1.599ThrGlu: 1.599 ± 1.196
0.799ThrPhe: 0.799 ± 0.598
2.398ThrGly: 2.398 ± 1.165
0.0ThrHis: 0.0 ± 0.0
4.796ThrIle: 4.796 ± 1.682
0.799ThrLys: 0.799 ± 0.655
3.197ThrLeu: 3.197 ± 0.884
1.599ThrMet: 1.599 ± 0.654
2.398ThrAsn: 2.398 ± 1.315
2.398ThrPro: 2.398 ± 0.13
1.599ThrGln: 1.599 ± 0.675
2.398ThrArg: 2.398 ± 1.315
3.197ThrSer: 3.197 ± 1.308
3.197ThrThr: 3.197 ± 1.308
2.398ThrVal: 2.398 ± 0.13
1.599ThrTrp: 1.599 ± 0.654
0.799ThrTyr: 0.799 ± 0.598
0.0ThrXaa: 0.0 ± 0.0
Val
9.592ValAla: 9.592 ± 3.074
1.599ValCys: 1.599 ± 1.311
2.398ValAsp: 2.398 ± 1.068
3.997ValGlu: 3.997 ± 0.549
1.599ValPhe: 1.599 ± 0.675
8.793ValGly: 8.793 ± 1.347
0.799ValHis: 0.799 ± 0.766
4.796ValIle: 4.796 ± 1.105
2.398ValLys: 2.398 ± 0.13
4.796ValLeu: 4.796 ± 0.26
2.398ValMet: 2.398 ± 2.097
2.398ValAsn: 2.398 ± 1.327
4.796ValPro: 4.796 ± 0.26
3.197ValGln: 3.197 ± 1.35
2.398ValArg: 2.398 ± 1.068
8.793ValSer: 8.793 ± 2.852
2.398ValThr: 2.398 ± 1.793
7.194ValVal: 7.194 ± 1.495
2.398ValTrp: 2.398 ± 1.315
3.197ValTyr: 3.197 ± 1.773
0.0ValXaa: 0.0 ± 0.0
Trp
2.398TrpAla: 2.398 ± 1.135
0.0TrpCys: 0.0 ± 0.0
3.197TrpAsp: 3.197 ± 2.044
2.398TrpGlu: 2.398 ± 1.315
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
3.997TrpHis: 3.997 ± 1.649
0.0TrpIle: 0.0 ± 0.0
3.197TrpLys: 3.197 ± 1.426
3.197TrpLeu: 3.197 ± 0.49
1.599TrpMet: 1.599 ± 1.311
2.398TrpAsn: 2.398 ± 1.068
0.0TrpPro: 0.0 ± 0.0
0.799TrpGln: 0.799 ± 0.598
2.398TrpArg: 2.398 ± 1.019
0.799TrpSer: 0.799 ± 0.766
0.799TrpThr: 0.799 ± 0.766
0.799TrpVal: 0.799 ± 0.766
0.0TrpTrp: 0.0 ± 0.0
0.799TrpTyr: 0.799 ± 0.766
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.599TyrAla: 1.599 ± 1.311
0.0TyrCys: 0.0 ± 0.0
2.398TyrAsp: 2.398 ± 1.327
1.599TyrGlu: 1.599 ± 0.675
0.799TyrPhe: 0.799 ± 0.766
3.997TyrGly: 3.997 ± 0.718
1.599TyrHis: 1.599 ± 0.675
3.197TyrIle: 3.197 ± 0.49
1.599TyrLys: 1.599 ± 1.196
3.197TyrLeu: 3.197 ± 0.884
1.599TyrMet: 1.599 ± 1.533
0.799TyrAsn: 0.799 ± 0.766
0.799TyrPro: 0.799 ± 0.766
0.799TyrGln: 0.799 ± 0.655
3.197TyrArg: 3.197 ± 0.884
2.398TyrSer: 2.398 ± 1.135
0.799TyrThr: 0.799 ± 0.655
2.398TyrVal: 2.398 ± 1.019
0.799TyrTrp: 0.799 ± 0.766
1.599TyrTyr: 1.599 ± 0.675
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.799XaaAsp: 0.799 ± 0.598
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1252 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski