Amino acid dipepetide frequency for Magnetovibrio blakemorei

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	11.49AlaAla: 11.49 ± 0.158	1.139AlaCys: 1.139 ± 0.038	6.078AlaAsp: 6.078 ± 0.106	6.492AlaGlu: 6.492 ± 0.104	4.065AlaPhe: 4.065 ± 0.072	8.062AlaGly: 8.062 ± 0.108	2.564AlaHis: 2.564 ± 0.049	5.617AlaIle: 5.617 ± 0.079	5.059AlaLys: 5.059 ± 0.084	11.656AlaLeu: 11.656 ± 0.135	3.165AlaMet: 3.165 ± 0.058	3.14AlaAsn: 3.14 ± 0.062	4.495AlaPro: 4.495 ± 0.089	4.446AlaGln: 4.446 ± 0.081	5.963AlaArg: 5.963 ± 0.09	5.425AlaSer: 5.425 ± 0.1	5.038AlaThr: 5.038 ± 0.102	7.525AlaVal: 7.525 ± 0.096	1.275AlaTrp: 1.275 ± 0.033	2.459AlaTyr: 2.459 ± 0.051	0.0AlaXaa: 0.0 ± 0.0
Cys	0.951CysAla: 0.951 ± 0.032	0.122CysCys: 0.122 ± 0.013	0.606CysAsp: 0.606 ± 0.024	0.516CysGlu: 0.516 ± 0.024	0.327CysPhe: 0.327 ± 0.016	0.973CysGly: 0.973 ± 0.037	0.356CysHis: 0.356 ± 0.024	0.514CysIle: 0.514 ± 0.026	0.347CysLys: 0.347 ± 0.018	0.795CysLeu: 0.795 ± 0.031	0.2CysMet: 0.2 ± 0.014	0.267CysAsn: 0.267 ± 0.015	0.555CysPro: 0.555 ± 0.029	0.351CysGln: 0.351 ± 0.016	0.514CysArg: 0.514 ± 0.025	0.497CysSer: 0.497 ± 0.024	0.566CysThr: 0.566 ± 0.024	0.788CysVal: 0.788 ± 0.028	0.116CysTrp: 0.116 ± 0.011	0.219CysTyr: 0.219 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	6.33AspAla: 6.33 ± 0.081	0.497AspCys: 0.497 ± 0.022	3.717AspAsp: 3.717 ± 0.063	3.911AspGlu: 3.911 ± 0.07	2.471AspPhe: 2.471 ± 0.052	5.356AspGly: 5.356 ± 0.121	1.41AspHis: 1.41 ± 0.043	3.814AspIle: 3.814 ± 0.064	2.539AspLys: 2.539 ± 0.059	6.114AspLeu: 6.114 ± 0.088	1.741AspMet: 1.741 ± 0.045	1.752AspAsn: 1.752 ± 0.041	2.896AspPro: 2.896 ± 0.059	2.149AspGln: 2.149 ± 0.044	3.05AspArg: 3.05 ± 0.057	2.521AspSer: 2.521 ± 0.048	3.237AspThr: 3.237 ± 0.066	5.121AspVal: 5.121 ± 0.065	0.903AspTrp: 0.903 ± 0.033	1.532AspTyr: 1.532 ± 0.042	0.0AspXaa: 0.0 ± 0.0
Glu	6.626GluAla: 6.626 ± 0.098	0.478GluCys: 0.478 ± 0.023	3.366GluAsp: 3.366 ± 0.053	3.244GluGlu: 3.244 ± 0.071	1.892GluPhe: 1.892 ± 0.046	4.119GluGly: 4.119 ± 0.074	1.552GluHis: 1.552 ± 0.043	3.613GluIle: 3.613 ± 0.073	2.826GluLys: 2.826 ± 0.064	5.668GluLeu: 5.668 ± 0.088	1.872GluMet: 1.872 ± 0.04	2.123GluAsn: 2.123 ± 0.051	2.285GluPro: 2.285 ± 0.052	2.397GluGln: 2.397 ± 0.049	4.092GluArg: 4.092 ± 0.076	2.547GluSer: 2.547 ± 0.049	3.482GluThr: 3.482 ± 0.062	4.207GluVal: 4.207 ± 0.083	0.639GluTrp: 0.639 ± 0.029	1.198GluTyr: 1.198 ± 0.034	0.001GluXaa: 0.001 ± 0.001
Phe	4.028PheAla: 4.028 ± 0.057	0.464PheCys: 0.464 ± 0.02	2.794PheAsp: 2.794 ± 0.051	2.401PheGlu: 2.401 ± 0.049	1.57PhePhe: 1.57 ± 0.042	3.373PheGly: 3.373 ± 0.065	0.785PheHis: 0.785 ± 0.03	1.969PheIle: 1.969 ± 0.052	1.624PheLys: 1.624 ± 0.04	3.422PheLeu: 3.422 ± 0.075	1.004PheMet: 1.004 ± 0.034	1.3PheAsn: 1.3 ± 0.035	1.453PhePro: 1.453 ± 0.04	1.172PheGln: 1.172 ± 0.03	1.687PheArg: 1.687 ± 0.045	2.512PheSer: 2.512 ± 0.056	2.247PheThr: 2.247 ± 0.061	2.823PheVal: 2.823 ± 0.061	0.529PheTrp: 0.529 ± 0.027	0.926PheTyr: 0.926 ± 0.032	0.0PheXaa: 0.0 ± 0.0
Gly	7.743GlyAla: 7.743 ± 0.127	0.901GlyCys: 0.901 ± 0.035	4.58GlyAsp: 4.58 ± 0.085	4.772GlyGlu: 4.772 ± 0.083	3.378GlyPhe: 3.378 ± 0.07	6.92GlyGly: 6.92 ± 0.109	1.996GlyHis: 1.996 ± 0.046	4.447GlyIle: 4.447 ± 0.073	3.67GlyLys: 3.67 ± 0.07	8.315GlyLeu: 8.315 ± 0.101	2.252GlyMet: 2.252 ± 0.05	2.35GlyAsn: 2.35 ± 0.065	2.776GlyPro: 2.776 ± 0.057	3.084GlyGln: 3.084 ± 0.059	4.521GlyArg: 4.521 ± 0.071	4.275GlySer: 4.275 ± 0.075	4.582GlyThr: 4.582 ± 0.123	6.449GlyVal: 6.449 ± 0.087	1.057GlyTrp: 1.057 ± 0.036	2.271GlyTyr: 2.271 ± 0.059	0.0GlyXaa: 0.0 ± 0.0
His	2.338HisAla: 2.338 ± 0.055	0.259HisCys: 0.259 ± 0.015	1.353HisAsp: 1.353 ± 0.04	1.32HisGlu: 1.32 ± 0.042	1.044HisPhe: 1.044 ± 0.032	1.94HisGly: 1.94 ± 0.044	0.695HisHis: 0.695 ± 0.034	1.368HisIle: 1.368 ± 0.034	0.962HisLys: 0.962 ± 0.031	2.401HisLeu: 2.401 ± 0.055	0.664HisMet: 0.664 ± 0.024	0.719HisAsn: 0.719 ± 0.03	1.384HisPro: 1.384 ± 0.044	0.766HisGln: 0.766 ± 0.026	1.247HisArg: 1.247 ± 0.037	1.102HisSer: 1.102 ± 0.032	1.221HisThr: 1.221 ± 0.033	1.694HisVal: 1.694 ± 0.045	0.319HisTrp: 0.319 ± 0.019	0.639HisTyr: 0.639 ± 0.024	0.0HisXaa: 0.0 ± 0.0
Ile	6.09IleAla: 6.09 ± 0.08	0.577IleCys: 0.577 ± 0.025	3.871IleAsp: 3.871 ± 0.065	3.901IleGlu: 3.901 ± 0.064	1.849IlePhe: 1.849 ± 0.05	4.709IleGly: 4.709 ± 0.074	1.171IleHis: 1.171 ± 0.039	3.003IleIle: 3.003 ± 0.061	2.641IleLys: 2.641 ± 0.052	5.119IleLeu: 5.119 ± 0.078	1.259IleMet: 1.259 ± 0.04	2.091IleAsn: 2.091 ± 0.046	2.385IlePro: 2.385 ± 0.047	1.685IleGln: 1.685 ± 0.04	2.808IleArg: 2.808 ± 0.061	3.617IleSer: 3.617 ± 0.06	3.292IleThr: 3.292 ± 0.061	4.157IleVal: 4.157 ± 0.076	0.578IleTrp: 0.578 ± 0.023	1.27IleTyr: 1.27 ± 0.039	0.0IleXaa: 0.0 ± 0.0
Lys	5.145LysAla: 5.145 ± 0.083	0.335LysCys: 0.335 ± 0.017	2.843LysAsp: 2.843 ± 0.068	2.2LysGlu: 2.2 ± 0.066	1.333LysPhe: 1.333 ± 0.042	3.422LysGly: 3.422 ± 0.076	0.993LysHis: 0.993 ± 0.033	2.601LysIle: 2.601 ± 0.055	2.367LysLys: 2.367 ± 0.075	4.167LysLeu: 4.167 ± 0.069	1.322LysMet: 1.322 ± 0.038	1.652LysAsn: 1.652 ± 0.046	2.404LysPro: 2.404 ± 0.057	1.425LysGln: 1.425 ± 0.042	2.922LysArg: 2.922 ± 0.064	2.76LysSer: 2.76 ± 0.055	3.032LysThr: 3.032 ± 0.061	3.119LysVal: 3.119 ± 0.064	0.514LysTrp: 0.514 ± 0.022	0.947LysTyr: 0.947 ± 0.031	0.0LysXaa: 0.0 ± 0.0
Leu	10.793LeuAla: 10.793 ± 0.105	0.891LeuCys: 0.891 ± 0.028	6.334LeuAsp: 6.334 ± 0.094	5.688LeuGlu: 5.688 ± 0.085	3.721LeuPhe: 3.721 ± 0.068	7.984LeuGly: 7.984 ± 0.098	2.14LeuHis: 2.14 ± 0.048	5.431LeuIle: 5.431 ± 0.086	5.137LeuLys: 5.137 ± 0.083	8.735LeuLeu: 8.735 ± 0.126	2.825LeuMet: 2.825 ± 0.054	3.649LeuAsn: 3.649 ± 0.064	4.606LeuPro: 4.606 ± 0.075	3.045LeuGln: 3.045 ± 0.059	5.36LeuArg: 5.36 ± 0.081	7.368LeuSer: 7.368 ± 0.096	5.57LeuThr: 5.57 ± 0.079	7.133LeuVal: 7.133 ± 0.083	1.026LeuTrp: 1.026 ± 0.042	2.142LeuTyr: 2.142 ± 0.054	0.0LeuXaa: 0.0 ± 0.0
Met	3.297MetAla: 3.297 ± 0.063	0.226MetCys: 0.226 ± 0.016	1.58MetAsp: 1.58 ± 0.039	1.454MetGlu: 1.454 ± 0.041	0.933MetPhe: 0.933 ± 0.033	2.239MetGly: 2.239 ± 0.054	0.55MetHis: 0.55 ± 0.022	1.506MetIle: 1.506 ± 0.04	1.314MetLys: 1.314 ± 0.039	2.522MetLeu: 2.522 ± 0.05	0.869MetMet: 0.869 ± 0.035	1.029MetAsn: 1.029 ± 0.03	1.408MetPro: 1.408 ± 0.034	0.874MetGln: 0.874 ± 0.031	1.624MetArg: 1.624 ± 0.04	2.032MetSer: 2.032 ± 0.047	1.834MetThr: 1.834 ± 0.044	2.04MetVal: 2.04 ± 0.047	0.289MetTrp: 0.289 ± 0.016	0.462MetTyr: 0.462 ± 0.023	0.0MetXaa: 0.0 ± 0.0
Asn	3.76AsnAla: 3.76 ± 0.065	0.321AsnCys: 0.321 ± 0.021	1.951AsnAsp: 1.951 ± 0.054	1.648AsnGlu: 1.648 ± 0.04	1.152AsnPhe: 1.152 ± 0.033	2.677AsnGly: 2.677 ± 0.06	0.734AsnHis: 0.734 ± 0.026	2.009AsnIle: 2.009 ± 0.044	1.303AsnLys: 1.303 ± 0.037	3.412AsnLeu: 3.412 ± 0.063	0.976AsnMet: 0.976 ± 0.035	1.081AsnAsn: 1.081 ± 0.041	1.972AsnPro: 1.972 ± 0.042	1.037AsnGln: 1.037 ± 0.035	1.827AsnArg: 1.827 ± 0.04	1.598AsnSer: 1.598 ± 0.044	1.892AsnThr: 1.892 ± 0.05	2.499AsnVal: 2.499 ± 0.046	0.455AsnTrp: 0.455 ± 0.019	0.78AsnTyr: 0.78 ± 0.029	0.0AsnXaa: 0.0 ± 0.0
Pro	4.269ProAla: 4.269 ± 0.084	0.341ProCys: 0.341 ± 0.018	3.16ProAsp: 3.16 ± 0.052	3.118ProGlu: 3.118 ± 0.066	1.865ProPhe: 1.865 ± 0.039	3.691ProGly: 3.691 ± 0.07	1.029ProHis: 1.029 ± 0.035	2.342ProIle: 2.342 ± 0.056	2.187ProLys: 2.187 ± 0.052	4.333ProLeu: 4.333 ± 0.074	1.181ProMet: 1.181 ± 0.031	1.52ProAsn: 1.52 ± 0.04	2.121ProPro: 2.121 ± 0.063	1.765ProGln: 1.765 ± 0.046	2.09ProArg: 2.09 ± 0.039	2.808ProSer: 2.808 ± 0.056	2.46ProThr: 2.46 ± 0.058	3.434ProVal: 3.434 ± 0.058	0.636ProTrp: 0.636 ± 0.027	1.274ProTyr: 1.274 ± 0.038	0.001ProXaa: 0.001 ± 0.001
Gln	4.26GlnAla: 4.26 ± 0.083	0.258GlnCys: 0.258 ± 0.016	2.131GlnAsp: 2.131 ± 0.048	1.75GlnGlu: 1.75 ± 0.042	1.132GlnPhe: 1.132 ± 0.038	2.797GlnGly: 2.797 ± 0.055	0.849GlnHis: 0.849 ± 0.03	1.939GlnIle: 1.939 ± 0.045	1.659GlnLys: 1.659 ± 0.046	3.102GlnLeu: 3.102 ± 0.054	1.083GlnMet: 1.083 ± 0.03	1.404GlnAsn: 1.404 ± 0.041	1.53GlnPro: 1.53 ± 0.044	1.204GlnGln: 1.204 ± 0.041	2.187GlnArg: 2.187 ± 0.051	2.194GlnSer: 2.194 ± 0.054	2.167GlnThr: 2.167 ± 0.048	2.785GlnVal: 2.785 ± 0.054	0.379GlnTrp: 0.379 ± 0.019	0.679GlnTyr: 0.679 ± 0.024	0.0GlnXaa: 0.0 ± 0.0
Arg	5.618ArgAla: 5.618 ± 0.076	0.489ArgCys: 0.489 ± 0.025	3.367ArgAsp: 3.367 ± 0.06	3.363ArgGlu: 3.363 ± 0.059	2.345ArgPhe: 2.345 ± 0.045	3.585ArgGly: 3.585 ± 0.056	1.491ArgHis: 1.491 ± 0.038	3.363ArgIle: 3.363 ± 0.053	2.43ArgLys: 2.43 ± 0.055	6.227ArgLeu: 6.227 ± 0.098	1.653ArgMet: 1.653 ± 0.039	1.715ArgAsn: 1.715 ± 0.042	2.474ArgPro: 2.474 ± 0.051	2.082ArgGln: 2.082 ± 0.047	3.63ArgArg: 3.63 ± 0.081	2.777ArgSer: 2.777 ± 0.054	3.039ArgThr: 3.039 ± 0.06	4.049ArgVal: 4.049 ± 0.072	0.708ArgTrp: 0.708 ± 0.025	1.462ArgTyr: 1.462 ± 0.038	0.0ArgXaa: 0.0 ± 0.0
Ser	5.899SerAla: 5.899 ± 0.092	0.553SerCys: 0.553 ± 0.022	3.458SerAsp: 3.458 ± 0.062	3.265SerGlu: 3.265 ± 0.061	2.269SerPhe: 2.269 ± 0.045	5.475SerGly: 5.475 ± 0.129	1.366SerHis: 1.366 ± 0.038	3.181SerIle: 3.181 ± 0.057	2.433SerLys: 2.433 ± 0.056	5.47SerLeu: 5.47 ± 0.078	1.579SerMet: 1.579 ± 0.041	1.835SerAsn: 1.835 ± 0.047	2.731SerPro: 2.731 ± 0.055	2.105SerGln: 2.105 ± 0.051	2.939SerArg: 2.939 ± 0.055	3.357SerSer: 3.357 ± 0.079	3.177SerThr: 3.177 ± 0.069	4.18SerVal: 4.18 ± 0.069	0.717SerTrp: 0.717 ± 0.025	1.425SerTyr: 1.425 ± 0.035	0.0SerXaa: 0.0 ± 0.0
Thr	5.502ThrAla: 5.502 ± 0.099	0.549ThrCys: 0.549 ± 0.027	3.384ThrAsp: 3.384 ± 0.063	2.754ThrGlu: 2.754 ± 0.055	2.243ThrPhe: 2.243 ± 0.064	4.644ThrGly: 4.644 ± 0.099	1.296ThrHis: 1.296 ± 0.038	3.254ThrIle: 3.254 ± 0.08	2.25ThrLys: 2.25 ± 0.048	6.093ThrLeu: 6.093 ± 0.095	1.303ThrMet: 1.303 ± 0.037	1.738ThrAsn: 1.738 ± 0.049	3.27ThrPro: 3.27 ± 0.064	2.018ThrGln: 2.018 ± 0.048	2.828ThrArg: 2.828 ± 0.056	3.2ThrSer: 3.2 ± 0.069	3.06ThrThr: 3.06 ± 0.074	4.628ThrVal: 4.628 ± 0.129	0.706ThrTrp: 0.706 ± 0.029	1.392ThrTyr: 1.392 ± 0.035	0.0ThrXaa: 0.0 ± 0.0
Val	7.53ValAla: 7.53 ± 0.11	0.788ValCys: 0.788 ± 0.031	4.344ValAsp: 4.344 ± 0.071	4.595ValGlu: 4.595 ± 0.076	3.057ValPhe: 3.057 ± 0.06	5.413ValGly: 5.413 ± 0.076	1.6ValHis: 1.6 ± 0.04	4.201ValIle: 4.201 ± 0.072	3.291ValLys: 3.291 ± 0.061	8.121ValLeu: 8.121 ± 0.101	2.177ValMet: 2.177 ± 0.057	2.457ValAsn: 2.457 ± 0.053	3.297ValPro: 3.297 ± 0.06	2.475ValGln: 2.475 ± 0.051	4.232ValArg: 4.232 ± 0.07	4.826ValSer: 4.826 ± 0.08	4.279ValThr: 4.279 ± 0.109	6.072ValVal: 6.072 ± 0.099	0.892ValTrp: 0.892 ± 0.025	1.664ValTyr: 1.664 ± 0.041	0.001ValXaa: 0.001 ± 0.001
Trp	1.123TrpAla: 1.123 ± 0.037	0.159TrpCys: 0.159 ± 0.012	0.682TrpAsp: 0.682 ± 0.028	0.512TrpGlu: 0.512 ± 0.023	0.436TrpPhe: 0.436 ± 0.027	0.901TrpGly: 0.901 ± 0.033	0.309TrpHis: 0.309 ± 0.018	0.649TrpIle: 0.649 ± 0.026	0.536TrpLys: 0.536 ± 0.026	1.444TrpLeu: 1.444 ± 0.043	0.352TrpMet: 0.352 ± 0.019	0.47TrpAsn: 0.47 ± 0.021	0.538TrpPro: 0.538 ± 0.023	0.558TrpGln: 0.558 ± 0.023	0.89TrpArg: 0.89 ± 0.032	0.72TrpSer: 0.72 ± 0.029	0.646TrpThr: 0.646 ± 0.029	0.894TrpVal: 0.894 ± 0.032	0.202TrpTrp: 0.202 ± 0.012	0.288TrpTyr: 0.288 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.363TyrAla: 2.363 ± 0.048	0.231TyrCys: 0.231 ± 0.017	1.463TyrAsp: 1.463 ± 0.04	1.323TyrGlu: 1.323 ± 0.049	1.001TyrPhe: 1.001 ± 0.033	2.057TyrGly: 2.057 ± 0.05	0.55TyrHis: 0.55 ± 0.024	1.253TyrIle: 1.253 ± 0.036	0.927TyrLys: 0.927 ± 0.033	2.459TyrLeu: 2.459 ± 0.053	0.604TyrMet: 0.604 ± 0.027	0.791TyrAsn: 0.791 ± 0.032	1.045TyrPro: 1.045 ± 0.035	0.851TyrGln: 0.851 ± 0.03	1.458TyrArg: 1.458 ± 0.038	1.277TyrSer: 1.277 ± 0.037	1.292TyrThr: 1.292 ± 0.043	1.716TyrVal: 1.716 ± 0.039	0.37TyrTrp: 0.37 ± 0.019	0.639TyrTyr: 0.639 ± 0.026	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.002XaaGly: 0.002 ± 0.002	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.001XaaLeu: 0.001 ± 0.001	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3316 proteins (1029642 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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