Tadarida brasiliensis circovirus 1

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cressdnaviricota; Arfiviricetes; Cirlivirales; Circoviridae; Circovirus; Bat associated circovirus 4

Average proteome isoelectric point is 8.67

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 2 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    

Protein with the lowest isoelectric point:
>tr|A0A0N9P0D8|A0A0N9P0D8_9CIRC Capsid protein OS=Tadarida brasiliensis circovirus 1 OX=1732201 GN=cap PE=3 SV=1
MM1 pKa = 7.11NVKK4 pKa = 10.23RR5 pKa = 11.84KK6 pKa = 9.86YY7 pKa = 9.09NAKK10 pKa = 10.4KK11 pKa = 10.43GDD13 pKa = 3.72EE14 pKa = 4.37TPGRR18 pKa = 11.84RR19 pKa = 11.84WCFTINNYY27 pKa = 8.5GAPDD31 pKa = 3.99LEE33 pKa = 4.73CVNEE37 pKa = 3.95AFRR40 pKa = 11.84CEE42 pKa = 4.03DD43 pKa = 3.05VVYY46 pKa = 10.3AICGKK51 pKa = 10.31EE52 pKa = 3.9KK53 pKa = 10.22GAKK56 pKa = 7.39GTPHH60 pKa = 6.27LQGFIHH66 pKa = 6.44FTGNWRR72 pKa = 11.84FNRR75 pKa = 11.84VRR77 pKa = 11.84NLLGGRR83 pKa = 11.84AHH85 pKa = 6.94IEE87 pKa = 3.84KK88 pKa = 10.73ARR90 pKa = 11.84GNDD93 pKa = 3.78DD94 pKa = 3.3QNKK97 pKa = 9.03AYY99 pKa = 10.16CSKK102 pKa = 10.83EE103 pKa = 3.66EE104 pKa = 4.14TYY106 pKa = 11.25LEE108 pKa = 4.24VGTPQFQGKK117 pKa = 9.93RR118 pKa = 11.84NDD120 pKa = 3.5LGRR123 pKa = 11.84VASALEE129 pKa = 4.16SGATLSEE136 pKa = 4.32VARR139 pKa = 11.84ASPEE143 pKa = 3.6VFIRR147 pKa = 11.84YY148 pKa = 8.71GRR150 pKa = 11.84GLRR153 pKa = 11.84DD154 pKa = 3.38YY155 pKa = 9.8MNVRR159 pKa = 11.84GLVKK163 pKa = 10.32PRR165 pKa = 11.84DD166 pKa = 3.78FKK168 pKa = 11.2TEE170 pKa = 4.0VIVLVGEE177 pKa = 4.32PGSGKK182 pKa = 10.21SKK184 pKa = 10.51YY185 pKa = 10.56ANEE188 pKa = 4.4LPGSKK193 pKa = 9.24YY194 pKa = 9.34WKK196 pKa = 9.87PRR198 pKa = 11.84GQWWDD203 pKa = 3.52GYY205 pKa = 9.64NGEE208 pKa = 5.22DD209 pKa = 4.59IVVLDD214 pKa = 5.32DD215 pKa = 3.98FYY217 pKa = 11.83GWVPYY222 pKa = 10.67DD223 pKa = 3.39EE224 pKa = 5.15LLRR227 pKa = 11.84IGDD230 pKa = 4.37RR231 pKa = 11.84YY232 pKa = 8.95PLKK235 pKa = 10.68VQVKK239 pKa = 8.31GAFVEE244 pKa = 5.43FTSKK248 pKa = 10.21MLVITSNKK256 pKa = 9.43RR257 pKa = 11.84PEE259 pKa = 3.55EE260 pKa = 4.22WYY262 pKa = 10.23DD263 pKa = 3.27KK264 pKa = 11.23EE265 pKa = 5.15KK266 pKa = 10.78IADD269 pKa = 3.62QSAMWRR275 pKa = 11.84RR276 pKa = 11.84FDD278 pKa = 3.87KK279 pKa = 10.3MYY281 pKa = 9.39YY282 pKa = 9.26CEE284 pKa = 4.17RR285 pKa = 11.84GEE287 pKa = 3.93PVKK290 pKa = 10.55AYY292 pKa = 8.08PHH294 pKa = 5.71EE295 pKa = 4.24WKK297 pKa = 10.61EE298 pKa = 3.93FEE300 pKa = 3.95TGYY303 pKa = 11.46

Molecular weight:
35.03 kDa
Isoelectric point according different methods:






Protein with the highest isoelectric point:
>tr|A0A0N9P0D8|A0A0N9P0D8_9CIRC Capsid protein OS=Tadarida brasiliensis circovirus 1 OX=1732201 GN=cap PE=3 SV=1
MM1 pKa = 7.27PRR3 pKa = 11.84SRR5 pKa = 11.84RR6 pKa = 11.84HH7 pKa = 4.13RR8 pKa = 11.84WRR10 pKa = 11.84RR11 pKa = 11.84NQWFKK16 pKa = 10.05RR17 pKa = 11.84WRR19 pKa = 11.84RR20 pKa = 11.84SRR22 pKa = 11.84RR23 pKa = 11.84RR24 pKa = 11.84GHH26 pKa = 5.42TFGTRR31 pKa = 11.84RR32 pKa = 11.84WRR34 pKa = 11.84QKK36 pKa = 10.18NGIYY40 pKa = 10.3NFKK43 pKa = 10.63FKK45 pKa = 11.02ANSLQTVNKK54 pKa = 9.06TSNQGYY60 pKa = 7.73FTFSLAAACPRR71 pKa = 11.84AFSTYY76 pKa = 9.1FDD78 pKa = 3.56MYY80 pKa = 10.15RR81 pKa = 11.84IRR83 pKa = 11.84KK84 pKa = 8.71VRR86 pKa = 11.84VQWLPMSGINEE97 pKa = 3.84PRR99 pKa = 11.84VWGATIIDD107 pKa = 3.72LTGRR111 pKa = 11.84DD112 pKa = 3.44TTLPSTGNTDD122 pKa = 3.67FTIDD126 pKa = 3.59DD127 pKa = 3.55VTRR130 pKa = 11.84RR131 pKa = 11.84IWNPTRR137 pKa = 11.84LHH139 pKa = 5.86SRR141 pKa = 11.84YY142 pKa = 7.56FTPKK146 pKa = 9.85PEE148 pKa = 3.95IAIKK152 pKa = 9.27TVSSEE157 pKa = 4.31AIQPNNPRR165 pKa = 11.84NQLWLDD171 pKa = 3.45AKK173 pKa = 11.12YY174 pKa = 10.59PDD176 pKa = 4.51AKK178 pKa = 10.7HH179 pKa = 6.27HH180 pKa = 5.94GCAFFFGQTDD190 pKa = 3.91LGDD193 pKa = 3.53EE194 pKa = 4.33SYY196 pKa = 11.31KK197 pKa = 10.73FQFLVTYY204 pKa = 8.22YY205 pKa = 10.02IQFRR209 pKa = 11.84QFAGSLAPSS218 pKa = 3.52

Molecular weight:
25.93 kDa
Isoelectric point according different methods:






Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

2

0

2

521

218

303

260.5

30.48

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.95 ± 0.008

1.536 ± 0.377

5.182 ± 0.363

5.758 ± 2.393

5.758 ± 1.245

8.061 ± 1.56

1.727 ± 0.345

4.031 ± 0.619

7.102 ± 1.254

5.374 ± 0.2

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.536 ± 0.097

5.182 ± 0.197

4.99 ± 0.314

3.455 ± 0.971

9.789 ± 1.584

4.798 ± 0.99

5.758 ± 1.804

5.566 ± 1.437

3.263 ± 0.248

5.182 ± 0.643

Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski