Amino acid dipepetide frequency for Saccharomyces cerevisiae virus L-A (ScV-L-A) (ScVL1)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.242AlaAla: 8.242 ± 0.293
1.832AlaCys: 1.832 ± 0.553
4.121AlaAsp: 4.121 ± 0.878
2.289AlaGlu: 2.289 ± 0.407
3.205AlaPhe: 3.205 ± 0.602
6.868AlaGly: 6.868 ± 1.708
2.747AlaHis: 2.747 ± 0.83
5.037AlaIle: 5.037 ± 0.423
3.205AlaLys: 3.205 ± 0.13
10.989AlaLeu: 10.989 ± 1.122
2.747AlaMet: 2.747 ± 0.634
5.037AlaAsn: 5.037 ± 1.041
2.289AlaPro: 2.289 ± 0.325
4.121AlaGln: 4.121 ± 0.146
4.579AlaArg: 4.579 ± 1.545
4.579AlaSer: 4.579 ± 0.813
2.747AlaThr: 2.747 ± 0.634
8.7AlaVal: 8.7 ± 0.667
4.579AlaTrp: 4.579 ± 0.651
5.952AlaTyr: 5.952 ± 0.765
0.0AlaXaa: 0.0 ± 0.0
Cys
1.832CysAla: 1.832 ± 0.179
0.916CysCys: 0.916 ± 0.277
0.0CysAsp: 0.0 ± 0.0
0.916CysGlu: 0.916 ± 0.455
1.832CysPhe: 1.832 ± 0.179
2.289CysGly: 2.289 ± 0.325
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.916CysAsn: 0.916 ± 0.455
0.458CysPro: 0.458 ± 0.228
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
1.832CysSer: 1.832 ± 0.553
0.916CysThr: 0.916 ± 0.277
0.916CysVal: 0.916 ± 0.455
0.0CysTrp: 0.0 ± 0.0
0.458CysTyr: 0.458 ± 0.228
0.0CysXaa: 0.0 ± 0.0
Asp
6.41AspAla: 6.41 ± 0.472
0.0AspCys: 0.0 ± 0.0
6.41AspAsp: 6.41 ± 0.26
1.832AspGlu: 1.832 ± 0.179
1.832AspPhe: 1.832 ± 0.179
4.579AspGly: 4.579 ± 0.651
1.374AspHis: 1.374 ± 0.049
1.832AspIle: 1.832 ± 0.179
3.205AspLys: 3.205 ± 0.602
3.663AspLeu: 3.663 ± 0.358
0.458AspMet: 0.458 ± 0.228
5.037AspAsn: 5.037 ± 1.155
1.374AspPro: 1.374 ± 0.683
2.289AspGln: 2.289 ± 0.407
3.663AspArg: 3.663 ± 0.374
3.663AspSer: 3.663 ± 0.358
8.242AspThr: 8.242 ± 0.293
6.41AspVal: 6.41 ± 0.26
1.832AspTrp: 1.832 ± 0.553
4.121AspTyr: 4.121 ± 0.586
0.0AspXaa: 0.0 ± 0.0
Glu
4.579GluAla: 4.579 ± 0.813
0.0GluCys: 0.0 ± 0.0
2.747GluAsp: 2.747 ± 0.098
0.916GluGlu: 0.916 ± 0.277
3.663GluPhe: 3.663 ± 0.358
4.121GluGly: 4.121 ± 0.878
0.458GluHis: 0.458 ± 0.228
0.916GluIle: 0.916 ± 0.455
0.916GluLys: 0.916 ± 0.455
5.952GluLeu: 5.952 ± 0.699
0.458GluMet: 0.458 ± 0.307
0.0GluAsn: 0.0 ± 0.0
3.663GluPro: 3.663 ± 0.358
2.289GluGln: 2.289 ± 0.325
1.832GluArg: 1.832 ± 0.179
1.832GluSer: 1.832 ± 0.179
1.374GluThr: 1.374 ± 0.049
3.205GluVal: 3.205 ± 0.602
2.747GluTrp: 2.747 ± 0.634
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
3.205PheAla: 3.205 ± 0.13
0.916PheCys: 0.916 ± 0.455
4.121PheAsp: 4.121 ± 0.146
0.916PheGlu: 0.916 ± 0.455
0.916PhePhe: 0.916 ± 0.277
3.205PheGly: 3.205 ± 0.13
0.0PheHis: 0.0 ± 0.0
0.458PheIle: 0.458 ± 0.228
2.289PheLys: 2.289 ± 0.325
3.205PheLeu: 3.205 ± 0.13
1.374PheMet: 1.374 ± 0.683
2.747PheAsn: 2.747 ± 0.098
2.289PhePro: 2.289 ± 0.325
0.0PheGln: 0.0 ± 0.0
3.205PheArg: 3.205 ± 0.13
3.663PheSer: 3.663 ± 0.358
2.289PheThr: 2.289 ± 0.325
7.784PheVal: 7.784 ± 1.984
0.458PheTrp: 0.458 ± 0.228
1.832PheTyr: 1.832 ± 0.553
0.0PheXaa: 0.0 ± 0.0
Gly
4.121GlyAla: 4.121 ± 0.878
0.0GlyCys: 0.0 ± 0.0
7.326GlyAsp: 7.326 ± 0.748
2.289GlyGlu: 2.289 ± 0.325
1.374GlyPhe: 1.374 ± 0.049
2.747GlyGly: 2.747 ± 0.634
1.374GlyHis: 1.374 ± 0.049
3.205GlyIle: 3.205 ± 0.602
0.458GlyLys: 0.458 ± 0.228
5.495GlyLeu: 5.495 ± 0.927
1.374GlyMet: 1.374 ± 0.049
2.747GlyAsn: 2.747 ± 0.83
1.832GlyPro: 1.832 ± 0.179
3.663GlyGln: 3.663 ± 0.358
1.374GlyArg: 1.374 ± 0.049
4.121GlySer: 4.121 ± 0.146
3.205GlyThr: 3.205 ± 0.13
4.121GlyVal: 4.121 ± 0.146
0.458GlyTrp: 0.458 ± 0.228
2.747GlyTyr: 2.747 ± 0.83
0.0GlyXaa: 0.0 ± 0.0
His
3.663HisAla: 3.663 ± 1.106
0.0HisCys: 0.0 ± 0.0
1.832HisAsp: 1.832 ± 0.553
0.458HisGlu: 0.458 ± 0.504
2.747HisPhe: 2.747 ± 0.098
1.832HisGly: 1.832 ± 0.179
0.458HisHis: 0.458 ± 0.228
0.916HisIle: 0.916 ± 0.277
1.374HisLys: 1.374 ± 0.683
2.289HisLeu: 2.289 ± 0.325
0.458HisMet: 0.458 ± 0.228
2.289HisAsn: 2.289 ± 0.325
0.0HisPro: 0.0 ± 0.0
0.0HisGln: 0.0 ± 0.0
2.289HisArg: 2.289 ± 0.407
1.374HisSer: 1.374 ± 0.683
1.832HisThr: 1.832 ± 0.911
3.205HisVal: 3.205 ± 0.602
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
2.289IleAla: 2.289 ± 0.407
0.916IleCys: 0.916 ± 0.277
5.037IleAsp: 5.037 ± 1.155
4.579IleGlu: 4.579 ± 0.651
1.832IlePhe: 1.832 ± 0.179
0.0IleGly: 0.0 ± 0.0
0.916IleHis: 0.916 ± 0.455
0.458IleIle: 0.458 ± 0.228
3.205IleLys: 3.205 ± 0.13
2.289IleLeu: 2.289 ± 1.139
2.289IleMet: 2.289 ± 0.325
2.289IleAsn: 2.289 ± 0.325
4.579IlePro: 4.579 ± 0.651
1.832IleGln: 1.832 ± 0.553
1.832IleArg: 1.832 ± 0.179
2.289IleSer: 2.289 ± 1.139
3.663IleThr: 3.663 ± 0.358
1.374IleVal: 1.374 ± 0.049
0.458IleTrp: 0.458 ± 0.228
1.832IleTyr: 1.832 ± 0.179
0.0IleXaa: 0.0 ± 0.0
Lys
2.747LysAla: 2.747 ± 0.634
0.458LysCys: 0.458 ± 0.228
0.916LysAsp: 0.916 ± 0.455
0.916LysGlu: 0.916 ± 0.455
6.41LysPhe: 6.41 ± 0.472
1.832LysGly: 1.832 ± 0.179
0.916LysHis: 0.916 ± 0.455
2.747LysIle: 2.747 ± 0.634
2.289LysLys: 2.289 ± 0.325
3.205LysLeu: 3.205 ± 0.602
0.458LysMet: 0.458 ± 0.228
2.747LysAsn: 2.747 ± 0.098
2.747LysPro: 2.747 ± 0.83
0.916LysGln: 0.916 ± 0.455
1.374LysArg: 1.374 ± 0.683
2.289LysSer: 2.289 ± 0.407
0.916LysThr: 0.916 ± 0.277
3.663LysVal: 3.663 ± 0.358
0.916LysTrp: 0.916 ± 0.277
4.121LysTyr: 4.121 ± 0.146
0.0LysXaa: 0.0 ± 0.0
Leu
8.7LeuAla: 8.7 ± 0.065
0.458LeuCys: 0.458 ± 0.228
5.952LeuAsp: 5.952 ± 0.765
4.579LeuGlu: 4.579 ± 0.651
2.289LeuPhe: 2.289 ± 0.407
0.916LeuGly: 0.916 ± 0.277
0.0LeuHis: 0.0 ± 0.0
1.832LeuIle: 1.832 ± 0.553
1.832LeuLys: 1.832 ± 0.179
4.579LeuLeu: 4.579 ± 0.651
3.663LeuMet: 3.663 ± 0.316
5.037LeuAsn: 5.037 ± 0.423
1.832LeuPro: 1.832 ± 0.553
3.663LeuGln: 3.663 ± 0.358
10.073LeuArg: 10.073 ± 0.114
4.579LeuSer: 4.579 ± 0.813
7.326LeuThr: 7.326 ± 0.748
5.952LeuVal: 5.952 ± 1.431
0.0LeuTrp: 0.0 ± 0.0
3.205LeuTyr: 3.205 ± 0.13
0.0LeuXaa: 0.0 ± 0.0
Met
1.374MetAla: 1.374 ± 0.049
0.458MetCys: 0.458 ± 0.228
0.916MetAsp: 0.916 ± 0.455
1.374MetGlu: 1.374 ± 0.049
0.916MetPhe: 0.916 ± 0.455
0.0MetGly: 0.0 ± 0.0
1.374MetHis: 1.374 ± 0.049
1.832MetIle: 1.832 ± 0.179
1.374MetLys: 1.374 ± 0.049
3.205MetLeu: 3.205 ± 0.602
3.205MetMet: 3.205 ± 0.602
2.289MetAsn: 2.289 ± 0.407
1.374MetPro: 1.374 ± 0.781
1.374MetGln: 1.374 ± 0.049
0.0MetArg: 0.0 ± 0.0
3.205MetSer: 3.205 ± 0.13
0.916MetThr: 0.916 ± 0.455
0.0MetVal: 0.0 ± 0.0
0.458MetTrp: 0.458 ± 0.228
1.832MetTyr: 1.832 ± 0.179
0.0MetXaa: 0.0 ± 0.0
Asn
2.747AsnAla: 2.747 ± 0.098
0.916AsnCys: 0.916 ± 0.277
0.916AsnAsp: 0.916 ± 0.455
3.205AsnGlu: 3.205 ± 0.13
2.747AsnPhe: 2.747 ± 0.098
2.289AsnGly: 2.289 ± 0.325
1.832AsnHis: 1.832 ± 0.553
4.121AsnIle: 4.121 ± 0.146
2.747AsnLys: 2.747 ± 0.634
4.121AsnLeu: 4.121 ± 0.146
2.289AsnMet: 2.289 ± 0.407
0.0AsnAsn: 0.0 ± 0.0
2.289AsnPro: 2.289 ± 0.325
0.916AsnGln: 0.916 ± 0.277
5.037AsnArg: 5.037 ± 0.309
2.289AsnSer: 2.289 ± 0.325
1.832AsnThr: 1.832 ± 0.179
2.289AsnVal: 2.289 ± 0.325
0.916AsnTrp: 0.916 ± 0.455
0.916AsnTyr: 0.916 ± 0.277
0.0AsnXaa: 0.0 ± 0.0
Pro
4.121ProAla: 4.121 ± 0.146
0.0ProCys: 0.0 ± 0.0
3.663ProAsp: 3.663 ± 0.358
3.205ProGlu: 3.205 ± 0.602
1.374ProPhe: 1.374 ± 0.049
3.205ProGly: 3.205 ± 0.862
0.0ProHis: 0.0 ± 0.0
1.374ProIle: 1.374 ± 0.049
1.832ProLys: 1.832 ± 0.179
3.205ProLeu: 3.205 ± 0.13
1.374ProMet: 1.374 ± 0.049
0.916ProAsn: 0.916 ± 0.277
1.832ProPro: 1.832 ± 0.179
0.916ProGln: 0.916 ± 0.277
2.289ProArg: 2.289 ± 0.407
3.663ProSer: 3.663 ± 0.374
3.663ProThr: 3.663 ± 1.106
5.495ProVal: 5.495 ± 0.927
0.0ProTrp: 0.0 ± 0.0
3.205ProTyr: 3.205 ± 0.602
0.0ProXaa: 0.0 ± 0.0
Gln
7.326GlnAla: 7.326 ± 0.716
0.458GlnCys: 0.458 ± 0.228
3.205GlnAsp: 3.205 ± 0.602
0.458GlnGlu: 0.458 ± 0.228
3.663GlnPhe: 3.663 ± 1.106
2.289GlnGly: 2.289 ± 0.325
0.916GlnHis: 0.916 ± 0.455
1.374GlnIle: 1.374 ± 0.049
1.374GlnLys: 1.374 ± 0.049
2.289GlnLeu: 2.289 ± 0.325
0.0GlnMet: 0.0 ± 0.0
0.0GlnAsn: 0.0 ± 0.0
1.374GlnPro: 1.374 ± 0.049
0.916GlnGln: 0.916 ± 0.277
0.458GlnArg: 0.458 ± 0.228
0.458GlnSer: 0.458 ± 0.228
0.916GlnThr: 0.916 ± 0.455
5.037GlnVal: 5.037 ± 0.423
0.0GlnTrp: 0.0 ± 0.0
2.289GlnTyr: 2.289 ± 0.407
0.0GlnXaa: 0.0 ± 0.0
Arg
4.121ArgAla: 4.121 ± 0.586
0.916ArgCys: 0.916 ± 0.455
1.832ArgAsp: 1.832 ± 0.911
0.0ArgGlu: 0.0 ± 0.0
1.832ArgPhe: 1.832 ± 0.179
2.747ArgGly: 2.747 ± 0.098
2.289ArgHis: 2.289 ± 0.325
2.747ArgIle: 2.747 ± 0.634
2.747ArgLys: 2.747 ± 0.098
5.495ArgLeu: 5.495 ± 1.269
0.458ArgMet: 0.458 ± 0.228
1.832ArgAsn: 1.832 ± 0.911
3.205ArgPro: 3.205 ± 0.13
0.916ArgGln: 0.916 ± 0.455
5.495ArgArg: 5.495 ± 0.195
5.495ArgSer: 5.495 ± 0.537
5.495ArgThr: 5.495 ± 0.195
8.242ArgVal: 8.242 ± 1.171
1.374ArgTrp: 1.374 ± 0.049
1.832ArgTyr: 1.832 ± 0.179
0.0ArgXaa: 0.0 ± 0.0
Ser
3.663SerAla: 3.663 ± 0.374
1.374SerCys: 1.374 ± 0.683
5.952SerAsp: 5.952 ± 0.033
2.289SerGlu: 2.289 ± 0.407
2.289SerPhe: 2.289 ± 0.407
2.747SerGly: 2.747 ± 0.634
1.832SerHis: 1.832 ± 0.179
4.579SerIle: 4.579 ± 0.081
3.663SerLys: 3.663 ± 0.358
0.916SerLeu: 0.916 ± 0.455
0.458SerMet: 0.458 ± 0.228
0.458SerAsn: 0.458 ± 0.228
3.205SerPro: 3.205 ± 0.13
3.205SerGln: 3.205 ± 0.13
4.579SerArg: 4.579 ± 1.545
4.579SerSer: 4.579 ± 0.081
5.952SerThr: 5.952 ± 0.033
4.579SerVal: 4.579 ± 0.081
1.832SerTrp: 1.832 ± 0.179
3.663SerTyr: 3.663 ± 0.374
0.0SerXaa: 0.0 ± 0.0
Thr
8.7ThrAla: 8.7 ± 0.065
0.916ThrCys: 0.916 ± 0.277
5.495ThrAsp: 5.495 ± 0.195
2.289ThrGlu: 2.289 ± 0.325
2.747ThrPhe: 2.747 ± 0.098
4.579ThrGly: 4.579 ± 1.383
5.037ThrHis: 5.037 ± 0.423
4.121ThrIle: 4.121 ± 0.146
3.663ThrLys: 3.663 ± 0.358
3.663ThrLeu: 3.663 ± 0.358
0.916ThrMet: 0.916 ± 0.277
1.832ThrAsn: 1.832 ± 0.179
0.458ThrPro: 0.458 ± 0.228
2.747ThrGln: 2.747 ± 0.83
1.832ThrArg: 1.832 ± 0.911
2.747ThrSer: 2.747 ± 0.634
2.747ThrThr: 2.747 ± 0.098
5.495ThrVal: 5.495 ± 0.195
1.832ThrTrp: 1.832 ± 0.179
4.579ThrTyr: 4.579 ± 0.813
0.0ThrXaa: 0.0 ± 0.0
Val
8.242ValAla: 8.242 ± 1.025
1.832ValCys: 1.832 ± 0.179
2.747ValAsp: 2.747 ± 0.634
4.121ValGlu: 4.121 ± 0.146
3.205ValPhe: 3.205 ± 0.602
4.121ValGly: 4.121 ± 0.146
1.832ValHis: 1.832 ± 0.911
4.121ValIle: 4.121 ± 0.146
2.747ValLys: 2.747 ± 0.83
5.952ValLeu: 5.952 ± 0.033
3.663ValMet: 3.663 ± 0.374
5.037ValAsn: 5.037 ± 0.309
5.037ValPro: 5.037 ± 0.423
4.579ValGln: 4.579 ± 0.081
5.495ValArg: 5.495 ± 0.537
5.952ValSer: 5.952 ± 0.033
8.242ValThr: 8.242 ± 1.025
4.121ValVal: 4.121 ± 0.146
0.458ValTrp: 0.458 ± 0.228
4.579ValTyr: 4.579 ± 1.383
0.0ValXaa: 0.0 ± 0.0
Trp
2.747TrpAla: 2.747 ± 0.098
0.0TrpCys: 0.0 ± 0.0
0.458TrpAsp: 0.458 ± 0.228
0.916TrpGlu: 0.916 ± 0.455
0.0TrpPhe: 0.0 ± 0.0
1.374TrpGly: 1.374 ± 0.049
0.916TrpHis: 0.916 ± 0.277
1.374TrpIle: 1.374 ± 0.049
1.374TrpLys: 1.374 ± 0.049
0.916TrpLeu: 0.916 ± 0.277
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
1.374TrpPro: 1.374 ± 0.049
0.458TrpGln: 0.458 ± 0.228
1.832TrpArg: 1.832 ± 0.179
0.916TrpSer: 0.916 ± 0.277
1.374TrpThr: 1.374 ± 0.049
1.832TrpVal: 1.832 ± 0.911
0.0TrpTrp: 0.0 ± 0.0
1.374TrpTyr: 1.374 ± 0.049
0.0TrpXaa: 0.0 ± 0.0
Tyr
5.037TyrAla: 5.037 ± 0.309
0.916TyrCys: 0.916 ± 0.277
4.579TyrAsp: 4.579 ± 0.651
4.121TyrGlu: 4.121 ± 0.586
0.0TyrPhe: 0.0 ± 0.0
2.289TyrGly: 2.289 ± 0.325
2.747TyrHis: 2.747 ± 0.83
0.916TyrIle: 0.916 ± 0.455
2.289TyrLys: 2.289 ± 1.139
5.495TyrLeu: 5.495 ± 0.927
1.374TyrMet: 1.374 ± 0.049
3.205TyrAsn: 3.205 ± 0.602
4.121TyrPro: 4.121 ± 0.146
0.0TyrGln: 0.0 ± 0.0
1.832TyrArg: 1.832 ± 0.179
2.289TyrSer: 2.289 ± 0.407
2.747TyrThr: 2.747 ± 0.634
3.663TyrVal: 3.663 ± 0.374
0.916TyrTrp: 0.916 ± 0.277
0.916TyrTyr: 0.916 ± 0.455
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2185 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski