human papillomavirus 87

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Alphapapillomavirus; Alphapapillomavirus 3

Average proteome isoelectric point is 6.78

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|Q9DIH7|Q9DIH7_9PAPI Protein E6 OS=human papillomavirus 87 OX=120381 GN=e6 PE=3 SV=2
MM1 pKa = 7.54HH2 pKa = 7.11GQTPTIKK9 pKa = 10.43DD10 pKa = 3.46IIISEE15 pKa = 4.13IPDD18 pKa = 3.71VVNLHH23 pKa = 6.93CDD25 pKa = 3.4EE26 pKa = 4.45QLLDD30 pKa = 3.78SSEE33 pKa = 4.49EE34 pKa = 3.92EE35 pKa = 4.2DD36 pKa = 4.59NRR38 pKa = 11.84DD39 pKa = 3.58CVRR42 pKa = 11.84DD43 pKa = 4.08QPAEE47 pKa = 3.96PAQLAHH53 pKa = 7.26RR54 pKa = 11.84VLTEE58 pKa = 3.86CGLCRR63 pKa = 11.84RR64 pKa = 11.84PVRR67 pKa = 11.84LVVLCGAGDD76 pKa = 3.96LRR78 pKa = 11.84QLQQLMVDD86 pKa = 4.23AVAIVCPGCAA96 pKa = 3.62

Molecular weight: 10.55 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|Q9DIH4|Q9DIH4_9PAPI Regulatory protein E2 OS=human papillomavirus 87 OX=120381 GN=e2 PE=3 SV=2
MM1 pKa = 6.64MVKK4 pKa = 7.76MTKK7 pKa = 8.96KK8 pKa = 8.81WNMSAGGIYY17 pKa = 9.68IYY19 pKa = 10.95SVLALIHH26 pKa = 6.31GLRR29 pKa = 11.84CLDD32 pKa = 3.5RR33 pKa = 11.84LATKK37 pKa = 10.3GYY39 pKa = 8.97IMNWKK44 pKa = 9.24AVNGTMLTLQRR55 pKa = 11.84RR56 pKa = 11.84QNTMGQKK63 pKa = 8.37TCGRR67 pKa = 11.84CMWEE71 pKa = 3.76AQLFTIHH78 pKa = 6.87ANLYY82 pKa = 8.04PVLRR86 pKa = 11.84EE87 pKa = 3.95ACQKK91 pKa = 10.71YY92 pKa = 9.64PLLQLLQSYY101 pKa = 7.15TTPPPRR107 pKa = 11.84PPLPPPRR114 pKa = 11.84KK115 pKa = 8.95PPRR118 pKa = 11.84CRR120 pKa = 11.84RR121 pKa = 11.84RR122 pKa = 11.84LLSDD126 pKa = 3.26SDD128 pKa = 4.43LEE130 pKa = 4.29EE131 pKa = 4.34TAPSSPILHH140 pKa = 6.17RR141 pKa = 11.84TSDD144 pKa = 3.9HH145 pKa = 6.36PWTVATHH152 pKa = 6.16GQTITLTTHH161 pKa = 6.41SGHH164 pKa = 5.91GTTVSVTVHH173 pKa = 6.35LSCTT177 pKa = 3.57

Molecular weight: 19.99 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

7

0

7

2465

96

626

352.1

39.54

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.004 ± 0.444

2.759 ± 0.637

5.598 ± 0.495

4.868 ± 0.7

3.448 ± 0.532

6.247 ± 0.302

2.677 ± 0.334

4.26 ± 0.386

4.706 ± 0.827

8.844 ± 0.658

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.272 ± 0.346

3.327 ± 0.451

6.694 ± 1.258

4.584 ± 0.681

5.882 ± 0.266

7.383 ± 0.952

7.87 ± 0.738

6.897 ± 0.476

1.663 ± 0.361

4.016 ± 0.46
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski