Amino acid dipepetide frequency for Candidatus Termititenax aidoneus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
12.415AlaAla: 12.415 ± 0.209
0.798AlaCys: 0.798 ± 0.036
5.616AlaAsp: 5.616 ± 0.099
7.852AlaGlu: 7.852 ± 0.138
2.798AlaPhe: 2.798 ± 0.056
7.506AlaGly: 7.506 ± 0.151
1.311AlaHis: 1.311 ± 0.05
4.171AlaIle: 4.171 ± 0.087
5.877AlaLys: 5.877 ± 0.103
10.008AlaLeu: 10.008 ± 0.168
1.637AlaMet: 1.637 ± 0.044
3.548AlaAsn: 3.548 ± 0.097
2.993AlaPro: 2.993 ± 0.08
4.07AlaGln: 4.07 ± 0.09
5.033AlaArg: 5.033 ± 0.105
3.964AlaSer: 3.964 ± 0.095
3.392AlaThr: 3.392 ± 0.091
7.05AlaVal: 7.05 ± 0.13
0.822AlaTrp: 0.822 ± 0.038
3.163AlaTyr: 3.163 ± 0.072
0.0AlaXaa: 0.0 ± 0.0
Cys
1.04CysAla: 1.04 ± 0.045
0.164CysCys: 0.164 ± 0.019
0.447CysAsp: 0.447 ± 0.028
0.463CysGlu: 0.463 ± 0.027
0.434CysPhe: 0.434 ± 0.026
1.079CysGly: 1.079 ± 0.046
0.183CysHis: 0.183 ± 0.015
0.44CysIle: 0.44 ± 0.033
0.463CysLys: 0.463 ± 0.028
1.043CysLeu: 1.043 ± 0.046
0.136CysMet: 0.136 ± 0.016
0.328CysAsn: 0.328 ± 0.026
0.489CysPro: 0.489 ± 0.033
0.407CysGln: 0.407 ± 0.029
0.615CysArg: 0.615 ± 0.036
0.486CysSer: 0.486 ± 0.028
0.365CysThr: 0.365 ± 0.024
0.55CysVal: 0.55 ± 0.033
0.097CysTrp: 0.097 ± 0.015
0.344CysTyr: 0.344 ± 0.02
0.0CysXaa: 0.0 ± 0.0
Asp
4.529AspAla: 4.529 ± 0.095
0.555AspCys: 0.555 ± 0.03
2.481AspAsp: 2.481 ± 0.07
3.077AspGlu: 3.077 ± 0.077
3.046AspPhe: 3.046 ± 0.061
3.963AspGly: 3.963 ± 0.102
0.61AspHis: 0.61 ± 0.03
4.234AspIle: 4.234 ± 0.083
3.824AspLys: 3.824 ± 0.08
5.543AspLeu: 5.543 ± 0.093
0.919AspMet: 0.919 ± 0.036
2.965AspAsn: 2.965 ± 0.093
2.06AspPro: 2.06 ± 0.063
1.502AspGln: 1.502 ± 0.047
2.451AspArg: 2.451 ± 0.064
3.002AspSer: 3.002 ± 0.071
3.144AspThr: 3.144 ± 0.099
2.903AspVal: 2.903 ± 0.07
0.764AspTrp: 0.764 ± 0.038
2.494AspTyr: 2.494 ± 0.067
0.0AspXaa: 0.0 ± 0.0
Glu
4.966GluAla: 4.966 ± 0.121
0.435GluCys: 0.435 ± 0.027
2.662GluAsp: 2.662 ± 0.072
3.635GluGlu: 3.635 ± 0.113
2.41GluPhe: 2.41 ± 0.064
2.584GluGly: 2.584 ± 0.073
1.123GluHis: 1.123 ± 0.043
5.645GluIle: 5.645 ± 0.105
5.923GluLys: 5.923 ± 0.124
7.179GluLeu: 7.179 ± 0.126
1.368GluMet: 1.368 ± 0.049
4.101GluAsn: 4.101 ± 0.08
1.811GluPro: 1.811 ± 0.06
2.98GluGln: 2.98 ± 0.08
3.068GluArg: 3.068 ± 0.074
2.603GluSer: 2.603 ± 0.079
3.729GluThr: 3.729 ± 0.084
3.253GluVal: 3.253 ± 0.083
0.648GluTrp: 0.648 ± 0.033
2.873GluTyr: 2.873 ± 0.078
0.0GluXaa: 0.0 ± 0.0
Phe
3.493PheAla: 3.493 ± 0.076
0.595PheCys: 0.595 ± 0.027
2.245PheAsp: 2.245 ± 0.055
1.998PheGlu: 1.998 ± 0.056
1.969PhePhe: 1.969 ± 0.066
2.993PheGly: 2.993 ± 0.078
0.602PheHis: 0.602 ± 0.028
2.44PheIle: 2.44 ± 0.068
2.208PheLys: 2.208 ± 0.067
4.093PheLeu: 4.093 ± 0.091
0.793PheMet: 0.793 ± 0.031
2.057PheAsn: 2.057 ± 0.062
1.401PhePro: 1.401 ± 0.048
1.412PheGln: 1.412 ± 0.05
1.739PheArg: 1.739 ± 0.049
3.085PheSer: 3.085 ± 0.081
2.319PheThr: 2.319 ± 0.055
2.571PheVal: 2.571 ± 0.06
0.605PheTrp: 0.605 ± 0.031
1.743PheTyr: 1.743 ± 0.055
0.0PheXaa: 0.0 ± 0.0
Gly
6.072GlyAla: 6.072 ± 0.139
0.757GlyCys: 0.757 ± 0.043
3.197GlyAsp: 3.197 ± 0.086
3.948GlyGlu: 3.948 ± 0.093
2.761GlyPhe: 2.761 ± 0.077
5.554GlyGly: 5.554 ± 0.146
1.157GlyHis: 1.157 ± 0.048
3.998GlyIle: 3.998 ± 0.08
4.475GlyLys: 4.475 ± 0.09
7.193GlyLeu: 7.193 ± 0.128
1.182GlyMet: 1.182 ± 0.048
3.235GlyAsn: 3.235 ± 0.109
1.191GlyPro: 1.191 ± 0.046
3.092GlyGln: 3.092 ± 0.067
3.656GlyArg: 3.656 ± 0.08
4.143GlySer: 4.143 ± 0.116
3.569GlyThr: 3.569 ± 0.11
4.833GlyVal: 4.833 ± 0.086
0.902GlyTrp: 0.902 ± 0.036
2.652GlyTyr: 2.652 ± 0.072
0.0GlyXaa: 0.0 ± 0.0
His
1.153HisAla: 1.153 ± 0.04
0.187HisCys: 0.187 ± 0.018
0.734HisAsp: 0.734 ± 0.034
0.773HisGlu: 0.773 ± 0.036
0.763HisPhe: 0.763 ± 0.035
1.221HisGly: 1.221 ± 0.046
0.301HisHis: 0.301 ± 0.021
1.055HisIle: 1.055 ± 0.037
1.2HisLys: 1.2 ± 0.044
1.468HisLeu: 1.468 ± 0.056
0.23HisMet: 0.23 ± 0.019
0.943HisAsn: 0.943 ± 0.041
0.645HisPro: 0.645 ± 0.03
0.5HisGln: 0.5 ± 0.032
0.734HisArg: 0.734 ± 0.032
1.051HisSer: 1.051 ± 0.042
1.074HisThr: 1.074 ± 0.065
0.666HisVal: 0.666 ± 0.033
0.183HisTrp: 0.183 ± 0.015
0.68HisTyr: 0.68 ± 0.03
0.0HisXaa: 0.0 ± 0.0
Ile
5.655IleAla: 5.655 ± 0.095
0.785IleCys: 0.785 ± 0.035
3.957IleAsp: 3.957 ± 0.092
4.081IleGlu: 4.081 ± 0.074
2.831IlePhe: 2.831 ± 0.069
4.05IleGly: 4.05 ± 0.088
0.95IleHis: 0.95 ± 0.034
4.532IleIle: 4.532 ± 0.089
4.484IleLys: 4.484 ± 0.089
6.289IleLeu: 6.289 ± 0.117
1.198IleMet: 1.198 ± 0.043
3.371IleAsn: 3.371 ± 0.079
2.459IlePro: 2.459 ± 0.06
2.236IleGln: 2.236 ± 0.05
2.878IleArg: 2.878 ± 0.063
4.599IleSer: 4.599 ± 0.094
3.961IleThr: 3.961 ± 0.094
4.141IleVal: 4.141 ± 0.086
0.601IleTrp: 0.601 ± 0.037
2.73IleTyr: 2.73 ± 0.071
0.0IleXaa: 0.0 ± 0.0
Lys
5.03LysAla: 5.03 ± 0.105
0.499LysCys: 0.499 ± 0.034
3.789LysAsp: 3.789 ± 0.092
4.457LysGlu: 4.457 ± 0.101
2.428LysPhe: 2.428 ± 0.068
3.073LysGly: 3.073 ± 0.072
1.252LysHis: 1.252 ± 0.051
6.423LysIle: 6.423 ± 0.118
5.568LysLys: 5.568 ± 0.139
6.715LysLeu: 6.715 ± 0.113
1.643LysMet: 1.643 ± 0.055
4.41LysAsn: 4.41 ± 0.101
2.261LysPro: 2.261 ± 0.058
2.64LysGln: 2.64 ± 0.066
2.565LysArg: 2.565 ± 0.068
3.034LysSer: 3.034 ± 0.072
4.534LysThr: 4.534 ± 0.09
3.632LysVal: 3.632 ± 0.089
0.58LysTrp: 0.58 ± 0.034
3.399LysTyr: 3.399 ± 0.08
0.0LysXaa: 0.0 ± 0.0
Leu
10.762LeuAla: 10.762 ± 0.162
0.948LeuCys: 0.948 ± 0.047
5.973LeuAsp: 5.973 ± 0.101
6.293LeuGlu: 6.293 ± 0.107
3.718LeuPhe: 3.718 ± 0.088
6.491LeuGly: 6.491 ± 0.129
1.632LeuHis: 1.632 ± 0.051
5.368LeuIle: 5.368 ± 0.109
7.109LeuLys: 7.109 ± 0.128
10.651LeuLeu: 10.651 ± 0.206
1.585LeuMet: 1.585 ± 0.047
5.244LeuAsn: 5.244 ± 0.095
4.863LeuPro: 4.863 ± 0.1
4.472LeuGln: 4.472 ± 0.098
6.07LeuArg: 6.07 ± 0.129
6.367LeuSer: 6.367 ± 0.108
6.2LeuThr: 6.2 ± 0.113
5.098LeuVal: 5.098 ± 0.106
0.862LeuTrp: 0.862 ± 0.038
3.136LeuTyr: 3.136 ± 0.078
0.0LeuXaa: 0.0 ± 0.0
Met
1.556MetAla: 1.556 ± 0.053
0.174MetCys: 0.174 ± 0.017
0.874MetAsp: 0.874 ± 0.034
0.958MetGlu: 0.958 ± 0.034
0.679MetPhe: 0.679 ± 0.033
0.937MetGly: 0.937 ± 0.037
0.325MetHis: 0.325 ± 0.019
0.981MetIle: 0.981 ± 0.037
0.973MetLys: 0.973 ± 0.041
2.296MetLeu: 2.296 ± 0.061
0.277MetMet: 0.277 ± 0.024
0.813MetAsn: 0.813 ± 0.037
0.99MetPro: 0.99 ± 0.04
0.86MetGln: 0.86 ± 0.041
1.029MetArg: 1.029 ± 0.041
1.238MetSer: 1.238 ± 0.044
1.095MetThr: 1.095 ± 0.039
0.993MetVal: 0.993 ± 0.043
0.12MetTrp: 0.12 ± 0.013
0.595MetTyr: 0.595 ± 0.029
0.0MetXaa: 0.0 ± 0.0
Asn
4.054AsnAla: 4.054 ± 0.094
0.478AsnCys: 0.478 ± 0.03
2.391AsnAsp: 2.391 ± 0.069
2.482AsnGlu: 2.482 ± 0.076
2.323AsnPhe: 2.323 ± 0.064
3.485AsnGly: 3.485 ± 0.098
0.623AsnHis: 0.623 ± 0.033
4.732AsnIle: 4.732 ± 0.108
3.585AsnLys: 3.585 ± 0.085
4.923AsnLeu: 4.923 ± 0.106
0.977AsnMet: 0.977 ± 0.039
3.002AsnAsn: 3.002 ± 0.101
2.496AsnPro: 2.496 ± 0.069
1.551AsnGln: 1.551 ± 0.047
1.858AsnArg: 1.858 ± 0.047
3.018AsnSer: 3.018 ± 0.105
2.958AsnThr: 2.958 ± 0.087
3.127AsnVal: 3.127 ± 0.065
0.633AsnTrp: 0.633 ± 0.03
2.403AsnTyr: 2.403 ± 0.075
0.0AsnXaa: 0.0 ± 0.0
Pro
3.964ProAla: 3.964 ± 0.083
0.331ProCys: 0.331 ± 0.025
2.723ProAsp: 2.723 ± 0.07
3.806ProGlu: 3.806 ± 0.084
1.383ProPhe: 1.383 ± 0.046
2.161ProGly: 2.161 ± 0.066
0.55ProHis: 0.55 ± 0.024
1.651ProIle: 1.651 ± 0.053
1.957ProLys: 1.957 ± 0.054
3.834ProLeu: 3.834 ± 0.08
0.48ProMet: 0.48 ± 0.026
1.78ProAsn: 1.78 ± 0.052
1.829ProPro: 1.829 ± 0.068
2.012ProGln: 2.012 ± 0.065
1.77ProArg: 1.77 ± 0.05
1.879ProSer: 1.879 ± 0.063
1.722ProThr: 1.722 ± 0.058
2.906ProVal: 2.906 ± 0.067
0.344ProTrp: 0.344 ± 0.021
1.333ProTyr: 1.333 ± 0.049
0.0ProXaa: 0.0 ± 0.0
Gln
3.831GlnAla: 3.831 ± 0.084
0.251GlnCys: 0.251 ± 0.023
2.152GlnAsp: 2.152 ± 0.061
2.866GlnGlu: 2.866 ± 0.076
1.164GlnPhe: 1.164 ± 0.048
2.02GlnGly: 2.02 ± 0.058
0.601GlnHis: 0.601 ± 0.034
2.953GlnIle: 2.953 ± 0.063
3.982GlnLys: 3.982 ± 0.085
3.209GlnLeu: 3.209 ± 0.082
0.832GlnMet: 0.832 ± 0.04
2.556GlnAsn: 2.556 ± 0.066
1.573GlnPro: 1.573 ± 0.056
1.588GlnGln: 1.588 ± 0.057
1.917GlnArg: 1.917 ± 0.064
1.899GlnSer: 1.899 ± 0.059
2.761GlnThr: 2.761 ± 0.077
2.127GlnVal: 2.127 ± 0.06
0.351GlnTrp: 0.351 ± 0.028
1.409GlnTyr: 1.409 ± 0.046
0.0GlnXaa: 0.0 ± 0.0
Arg
4.29ArgAla: 4.29 ± 0.09
0.413ArgCys: 0.413 ± 0.027
2.509ArgAsp: 2.509 ± 0.067
3.591ArgGlu: 3.591 ± 0.085
1.939ArgPhe: 1.939 ± 0.054
3.206ArgGly: 3.206 ± 0.073
0.825ArgHis: 0.825 ± 0.031
3.167ArgIle: 3.167 ± 0.077
3.38ArgLys: 3.38 ± 0.088
5.337ArgLeu: 5.337 ± 0.127
0.857ArgMet: 0.857 ± 0.04
2.26ArgAsn: 2.26 ± 0.066
1.812ArgPro: 1.812 ± 0.054
2.633ArgGln: 2.633 ± 0.062
2.952ArgArg: 2.952 ± 0.086
2.389ArgSer: 2.389 ± 0.064
2.28ArgThr: 2.28 ± 0.06
2.884ArgVal: 2.884 ± 0.061
0.55ArgTrp: 0.55 ± 0.029
1.896ArgTyr: 1.896 ± 0.06
0.0ArgXaa: 0.0 ± 0.0
Ser
6.225SerAla: 6.225 ± 0.122
0.552SerCys: 0.552 ± 0.035
2.853SerAsp: 2.853 ± 0.089
3.096SerGlu: 3.096 ± 0.067
2.447SerPhe: 2.447 ± 0.064
6.051SerGly: 6.051 ± 0.14
0.776SerHis: 0.776 ± 0.044
3.406SerIle: 3.406 ± 0.073
2.848SerLys: 2.848 ± 0.078
5.38SerLeu: 5.38 ± 0.109
0.973SerMet: 0.973 ± 0.046
2.32SerAsn: 2.32 ± 0.069
2.326SerPro: 2.326 ± 0.062
1.672SerGln: 1.672 ± 0.046
2.667SerArg: 2.667 ± 0.062
3.421SerSer: 3.421 ± 0.137
2.745SerThr: 2.745 ± 0.078
3.963SerVal: 3.963 ± 0.087
0.595SerTrp: 0.595 ± 0.033
2.068SerTyr: 2.068 ± 0.069
0.0SerXaa: 0.0 ± 0.0
Thr
6.141ThrAla: 6.141 ± 0.121
0.357ThrCys: 0.357 ± 0.021
3.195ThrAsp: 3.195 ± 0.092
3.3ThrGlu: 3.3 ± 0.078
1.976ThrPhe: 1.976 ± 0.062
4.58ThrGly: 4.58 ± 0.102
0.965ThrHis: 0.965 ± 0.046
3.818ThrIle: 3.818 ± 0.116
3.054ThrLys: 3.054 ± 0.069
5.682ThrLeu: 5.682 ± 0.126
0.881ThrMet: 0.881 ± 0.04
2.372ThrAsn: 2.372 ± 0.075
2.724ThrPro: 2.724 ± 0.074
1.774ThrGln: 1.774 ± 0.057
2.273ThrArg: 2.273 ± 0.055
2.755ThrSer: 2.755 ± 0.084
3.124ThrThr: 3.124 ± 0.099
3.933ThrVal: 3.933 ± 0.113
0.441ThrTrp: 0.441 ± 0.03
1.926ThrTyr: 1.926 ± 0.069
0.0ThrXaa: 0.0 ± 0.0
Val
4.723ValAla: 4.723 ± 0.106
0.767ValCys: 0.767 ± 0.034
3.338ValAsp: 3.338 ± 0.071
3.606ValGlu: 3.606 ± 0.083
2.933ValPhe: 2.933 ± 0.075
3.449ValGly: 3.449 ± 0.087
0.838ValHis: 0.838 ± 0.036
3.84ValIle: 3.84 ± 0.083
4.004ValLys: 4.004 ± 0.088
6.582ValLeu: 6.582 ± 0.108
1.054ValMet: 1.054 ± 0.042
3.178ValAsn: 3.178 ± 0.076
2.431ValPro: 2.431 ± 0.054
2.161ValGln: 2.161 ± 0.06
3.186ValArg: 3.186 ± 0.078
4.463ValSer: 4.463 ± 0.098
3.24ValThr: 3.24 ± 0.114
3.938ValVal: 3.938 ± 0.093
0.735ValTrp: 0.735 ± 0.039
2.583ValTyr: 2.583 ± 0.07
0.0ValXaa: 0.0 ± 0.0
Trp
0.68TrpAla: 0.68 ± 0.035
0.118TrpCys: 0.118 ± 0.016
0.642TrpAsp: 0.642 ± 0.036
0.59TrpGlu: 0.59 ± 0.035
0.474TrpPhe: 0.474 ± 0.026
0.657TrpGly: 0.657 ± 0.04
0.27TrpHis: 0.27 ± 0.026
0.46TrpIle: 0.46 ± 0.029
0.514TrpLys: 0.514 ± 0.025
1.249TrpLeu: 1.249 ± 0.05
0.115TrpMet: 0.115 ± 0.013
0.536TrpAsn: 0.536 ± 0.03
0.419TrpPro: 0.419 ± 0.025
0.787TrpGln: 0.787 ± 0.037
0.734TrpArg: 0.734 ± 0.034
0.638TrpSer: 0.638 ± 0.037
0.657TrpThr: 0.657 ± 0.047
0.463TrpVal: 0.463 ± 0.032
0.161TrpTrp: 0.161 ± 0.015
0.342TrpTyr: 0.342 ± 0.023
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.442TyrAla: 3.442 ± 0.074
0.409TyrCys: 0.409 ± 0.029
2.292TyrAsp: 2.292 ± 0.085
2.125TyrGlu: 2.125 ± 0.07
1.883TyrPhe: 1.883 ± 0.063
2.509TyrGly: 2.509 ± 0.07
0.667TyrHis: 0.667 ± 0.037
2.472TyrIle: 2.472 ± 0.057
2.505TyrLys: 2.505 ± 0.074
4.168TyrLeu: 4.168 ± 0.099
0.624TyrMet: 0.624 ± 0.035
2.081TyrAsn: 2.081 ± 0.066
1.641TyrPro: 1.641 ± 0.056
1.694TyrGln: 1.694 ± 0.054
1.978TyrArg: 1.978 ± 0.052
2.35TyrSer: 2.35 ± 0.069
2.404TyrThr: 2.404 ± 0.074
2.016TyrVal: 2.016 ± 0.059
0.511TyrTrp: 0.511 ± 0.036
1.821TyrTyr: 1.821 ± 0.074
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2306 proteins (677573 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski