Amino acid dipepetide frequency for Corynebacterium endometrii

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	16.637AlaAla: 16.637 ± 0.278	0.989AlaCys: 0.989 ± 0.038	6.871AlaAsp: 6.871 ± 0.095	8.206AlaGlu: 8.206 ± 0.151	3.699AlaPhe: 3.699 ± 0.075	10.795AlaGly: 10.795 ± 0.138	2.301AlaHis: 2.301 ± 0.065	5.728AlaIle: 5.728 ± 0.098	4.027AlaLys: 4.027 ± 0.091	11.615AlaLeu: 11.615 ± 0.169	2.943AlaMet: 2.943 ± 0.069	3.173AlaAsn: 3.173 ± 0.079	5.365AlaPro: 5.365 ± 0.129	4.366AlaGln: 4.366 ± 0.089	7.423AlaArg: 7.423 ± 0.131	6.207AlaSer: 6.207 ± 0.104	6.654AlaThr: 6.654 ± 0.118	9.668AlaVal: 9.668 ± 0.14	1.58AlaTrp: 1.58 ± 0.051	2.464AlaTyr: 2.464 ± 0.059	0.0AlaXaa: 0.0 ± 0.0
Cys	0.885CysAla: 0.885 ± 0.037	0.067CysCys: 0.067 ± 0.01	0.404CysAsp: 0.404 ± 0.025	0.425CysGlu: 0.425 ± 0.024	0.229CysPhe: 0.229 ± 0.018	0.796CysGly: 0.796 ± 0.037	0.17CysHis: 0.17 ± 0.016	0.325CysIle: 0.325 ± 0.019	0.174CysLys: 0.174 ± 0.018	0.555CysLeu: 0.555 ± 0.027	0.145CysMet: 0.145 ± 0.014	0.184CysAsn: 0.184 ± 0.016	0.427CysPro: 0.427 ± 0.029	0.218CysGln: 0.218 ± 0.018	0.364CysArg: 0.364 ± 0.023	0.449CysSer: 0.449 ± 0.027	0.421CysThr: 0.421 ± 0.024	0.598CysVal: 0.598 ± 0.029	0.081CysTrp: 0.081 ± 0.009	0.159CysTyr: 0.159 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	6.979AspAla: 6.979 ± 0.106	0.425AspCys: 0.425 ± 0.021	3.203AspAsp: 3.203 ± 0.095	4.318AspGlu: 4.318 ± 0.09	2.146AspPhe: 2.146 ± 0.059	5.096AspGly: 5.096 ± 0.099	1.146AspHis: 1.146 ± 0.042	2.945AspIle: 2.945 ± 0.071	2.204AspLys: 2.204 ± 0.06	5.301AspLeu: 5.301 ± 0.097	1.191AspMet: 1.191 ± 0.041	1.852AspAsn: 1.852 ± 0.06	3.383AspPro: 3.383 ± 0.073	1.613AspGln: 1.613 ± 0.052	3.235AspArg: 3.235 ± 0.081	3.546AspSer: 3.546 ± 0.077	2.833AspThr: 2.833 ± 0.061	4.601AspVal: 4.601 ± 0.082	0.824AspTrp: 0.824 ± 0.035	1.581AspTyr: 1.581 ± 0.05	0.0AspXaa: 0.0 ± 0.0
Glu	7.751GluAla: 7.751 ± 0.133	0.388GluCys: 0.388 ± 0.023	3.94GluAsp: 3.94 ± 0.075	4.982GluGlu: 4.982 ± 0.11	2.197GluPhe: 2.197 ± 0.055	5.086GluGly: 5.086 ± 0.095	1.482GluHis: 1.482 ± 0.047	3.364GluIle: 3.364 ± 0.072	2.405GluLys: 2.405 ± 0.069	7.163GluLeu: 7.163 ± 0.112	1.372GluMet: 1.372 ± 0.045	1.736GluAsn: 1.736 ± 0.051	3.076GluPro: 3.076 ± 0.073	2.528GluGln: 2.528 ± 0.062	4.424GluArg: 4.424 ± 0.099	3.586GluSer: 3.586 ± 0.067	3.445GluThr: 3.445 ± 0.081	5.176GluVal: 5.176 ± 0.11	0.856GluTrp: 0.856 ± 0.034	1.574GluTyr: 1.574 ± 0.049	0.0GluXaa: 0.0 ± 0.0
Phe	3.813PheAla: 3.813 ± 0.083	0.259PheCys: 0.259 ± 0.022	2.296PheAsp: 2.296 ± 0.059	2.055PheGlu: 2.055 ± 0.054	1.277PhePhe: 1.277 ± 0.048	3.415PheGly: 3.415 ± 0.076	0.699PheHis: 0.699 ± 0.029	1.899PheIle: 1.899 ± 0.062	1.014PheLys: 1.014 ± 0.039	2.892PheLeu: 2.892 ± 0.08	0.732PheMet: 0.732 ± 0.033	1.129PheAsn: 1.129 ± 0.04	1.517PhePro: 1.517 ± 0.05	0.828PheGln: 0.828 ± 0.035	1.609PheArg: 1.609 ± 0.05	2.104PheSer: 2.104 ± 0.056	2.111PheThr: 2.111 ± 0.047	2.568PheVal: 2.568 ± 0.071	0.47PheTrp: 0.47 ± 0.024	0.813PheTyr: 0.813 ± 0.035	0.0PheXaa: 0.0 ± 0.0
Gly	9.357GlyAla: 9.357 ± 0.155	0.694GlyCys: 0.694 ± 0.032	4.551GlyAsp: 4.551 ± 0.085	5.452GlyGlu: 5.452 ± 0.087	3.345GlyPhe: 3.345 ± 0.084	7.351GlyGly: 7.351 ± 0.15	1.903GlyHis: 1.903 ± 0.053	4.791GlyIle: 4.791 ± 0.089	3.268GlyLys: 3.268 ± 0.08	8.469GlyLeu: 8.469 ± 0.131	2.278GlyMet: 2.278 ± 0.06	2.599GlyAsn: 2.599 ± 0.063	3.441GlyPro: 3.441 ± 0.072	3.016GlyGln: 3.016 ± 0.061	5.149GlyArg: 5.149 ± 0.102	5.088GlySer: 5.088 ± 0.092	5.042GlyThr: 5.042 ± 0.094	7.182GlyVal: 7.182 ± 0.102	1.372GlyTrp: 1.372 ± 0.048	2.355GlyTyr: 2.355 ± 0.066	0.0GlyXaa: 0.0 ± 0.0
His	2.143HisAla: 2.143 ± 0.058	0.158HisCys: 0.158 ± 0.016	1.168HisAsp: 1.168 ± 0.046	1.272HisGlu: 1.272 ± 0.044	0.619HisPhe: 0.619 ± 0.031	1.885HisGly: 1.885 ± 0.05	0.526HisHis: 0.526 ± 0.025	1.0HisIle: 1.0 ± 0.039	0.555HisLys: 0.555 ± 0.029	1.871HisLeu: 1.871 ± 0.056	0.439HisMet: 0.439 ± 0.026	0.669HisAsn: 0.669 ± 0.031	1.385HisPro: 1.385 ± 0.048	0.583HisGln: 0.583 ± 0.03	1.279HisArg: 1.279 ± 0.044	1.15HisSer: 1.15 ± 0.043	1.135HisThr: 1.135 ± 0.045	1.535HisVal: 1.535 ± 0.05	0.268HisTrp: 0.268 ± 0.019	0.515HisTyr: 0.515 ± 0.028	0.0HisXaa: 0.0 ± 0.0
Ile	6.556IleAla: 6.556 ± 0.108	0.395IleCys: 0.395 ± 0.03	3.479IleAsp: 3.479 ± 0.07	3.489IleGlu: 3.489 ± 0.082	1.712IlePhe: 1.712 ± 0.055	4.381IleGly: 4.381 ± 0.085	1.011IleHis: 1.011 ± 0.036	2.922IleIle: 2.922 ± 0.082	1.584IleLys: 1.584 ± 0.047	4.021IleLeu: 4.021 ± 0.091	1.075IleMet: 1.075 ± 0.039	1.715IleAsn: 1.715 ± 0.047	2.692IlePro: 2.692 ± 0.063	1.291IleGln: 1.291 ± 0.042	2.645IleArg: 2.645 ± 0.072	2.943IleSer: 2.943 ± 0.071	3.116IleThr: 3.116 ± 0.067	4.144IleVal: 4.144 ± 0.077	0.515IleTrp: 0.515 ± 0.03	1.078IleTyr: 1.078 ± 0.048	0.0IleXaa: 0.0 ± 0.0
Lys	4.202LysAla: 4.202 ± 0.087	0.123LysCys: 0.123 ± 0.012	2.082LysAsp: 2.082 ± 0.057	2.347LysGlu: 2.347 ± 0.061	0.956LysPhe: 0.956 ± 0.04	2.472LysGly: 2.472 ± 0.07	0.671LysHis: 0.671 ± 0.024	1.573LysIle: 1.573 ± 0.05	1.824LysLys: 1.824 ± 0.067	3.193LysLeu: 3.193 ± 0.068	0.805LysMet: 0.805 ± 0.035	1.032LysAsn: 1.032 ± 0.04	1.796LysPro: 1.796 ± 0.063	1.156LysGln: 1.156 ± 0.036	2.262LysArg: 2.262 ± 0.056	1.839LysSer: 1.839 ± 0.055	1.776LysThr: 1.776 ± 0.051	2.695LysVal: 2.695 ± 0.069	0.389LysTrp: 0.389 ± 0.026	0.789LysTyr: 0.789 ± 0.032	0.0LysXaa: 0.0 ± 0.0
Leu	11.944LeuAla: 11.944 ± 0.15	0.683LeuCys: 0.683 ± 0.034	5.782LeuAsp: 5.782 ± 0.112	5.682LeuGlu: 5.682 ± 0.103	2.943LeuPhe: 2.943 ± 0.076	8.592LeuGly: 8.592 ± 0.126	1.775LeuHis: 1.775 ± 0.049	5.054LeuIle: 5.054 ± 0.102	3.015LeuLys: 3.015 ± 0.071	8.233LeuLeu: 8.233 ± 0.131	1.994LeuMet: 1.994 ± 0.061	2.692LeuAsn: 2.692 ± 0.061	5.063LeuPro: 5.063 ± 0.091	2.451LeuGln: 2.451 ± 0.061	5.813LeuArg: 5.813 ± 0.103	5.68LeuSer: 5.68 ± 0.091	5.64LeuThr: 5.64 ± 0.093	7.306LeuVal: 7.306 ± 0.115	1.141LeuTrp: 1.141 ± 0.046	1.87LeuTyr: 1.87 ± 0.049	0.0LeuXaa: 0.0 ± 0.0
Met	2.819MetAla: 2.819 ± 0.063	0.173MetCys: 0.173 ± 0.017	1.253MetAsp: 1.253 ± 0.043	1.196MetGlu: 1.196 ± 0.045	0.733MetPhe: 0.733 ± 0.031	1.997MetGly: 1.997 ± 0.057	0.402MetHis: 0.402 ± 0.023	1.069MetIle: 1.069 ± 0.042	0.763MetLys: 0.763 ± 0.034	2.232MetLeu: 2.232 ± 0.06	0.506MetMet: 0.506 ± 0.024	0.742MetAsn: 0.742 ± 0.031	1.145MetPro: 1.145 ± 0.045	0.615MetGln: 0.615 ± 0.029	1.361MetArg: 1.361 ± 0.047	1.682MetSer: 1.682 ± 0.057	1.656MetThr: 1.656 ± 0.052	1.828MetVal: 1.828 ± 0.049	0.289MetTrp: 0.289 ± 0.021	0.396MetTyr: 0.396 ± 0.024	0.0MetXaa: 0.0 ± 0.0
Asn	3.263AsnAla: 3.263 ± 0.071	0.197AsnCys: 0.197 ± 0.018	1.509AsnAsp: 1.509 ± 0.052	1.765AsnGlu: 1.765 ± 0.052	1.026AsnPhe: 1.026 ± 0.037	2.49AsnGly: 2.49 ± 0.065	0.566AsnHis: 0.566 ± 0.033	1.397AsnIle: 1.397 ± 0.047	1.014AsnLys: 1.014 ± 0.044	2.715AsnLeu: 2.715 ± 0.055	0.633AsnMet: 0.633 ± 0.031	0.977AsnAsn: 0.977 ± 0.043	2.366AsnPro: 2.366 ± 0.061	1.022AsnGln: 1.022 ± 0.043	1.704AsnArg: 1.704 ± 0.051	1.822AsnSer: 1.822 ± 0.057	1.564AsnThr: 1.564 ± 0.044	2.195AsnVal: 2.195 ± 0.055	0.427AsnTrp: 0.427 ± 0.024	0.814AsnTyr: 0.814 ± 0.032	0.0AsnXaa: 0.0 ± 0.0
Pro	6.127ProAla: 6.127 ± 0.122	0.244ProCys: 0.244 ± 0.019	3.199ProAsp: 3.199 ± 0.065	4.579ProGlu: 4.579 ± 0.098	1.581ProPhe: 1.581 ± 0.047	4.565ProGly: 4.565 ± 0.09	1.081ProHis: 1.081 ± 0.038	2.069ProIle: 2.069 ± 0.059	1.577ProLys: 1.577 ± 0.05	4.307ProLeu: 4.307 ± 0.079	1.012ProMet: 1.012 ± 0.038	1.421ProAsn: 1.421 ± 0.051	1.729ProPro: 1.729 ± 0.062	2.023ProGln: 2.023 ± 0.057	2.906ProArg: 2.906 ± 0.075	2.929ProSer: 2.929 ± 0.065	2.911ProThr: 2.911 ± 0.068	4.387ProVal: 4.387 ± 0.081	0.7ProTrp: 0.7 ± 0.032	1.071ProTyr: 1.071 ± 0.041	0.0ProXaa: 0.0 ± 0.0
Gln	4.24GlnAla: 4.24 ± 0.072	0.167GlnCys: 0.167 ± 0.015	1.698GlnAsp: 1.698 ± 0.048	2.02GlnGlu: 2.02 ± 0.055	1.011GlnPhe: 1.011 ± 0.041	2.387GlnGly: 2.387 ± 0.059	0.602GlnHis: 0.602 ± 0.033	1.527GlnIle: 1.527 ± 0.048	0.941GlnLys: 0.941 ± 0.032	3.54GlnLeu: 3.54 ± 0.073	0.81GlnMet: 0.81 ± 0.032	0.788GlnAsn: 0.788 ± 0.034	1.728GlnPro: 1.728 ± 0.06	1.365GlnGln: 1.365 ± 0.053	2.545GlnArg: 2.545 ± 0.064	1.596GlnSer: 1.596 ± 0.06	1.47GlnThr: 1.47 ± 0.048	2.55GlnVal: 2.55 ± 0.058	0.535GlnTrp: 0.535 ± 0.028	0.673GlnTyr: 0.673 ± 0.035	0.0GlnXaa: 0.0 ± 0.0
Arg	6.595ArgAla: 6.595 ± 0.112	0.386ArgCys: 0.386 ± 0.022	3.592ArgAsp: 3.592 ± 0.074	4.534ArgGlu: 4.534 ± 0.09	2.054ArgPhe: 2.054 ± 0.062	4.798ArgGly: 4.798 ± 0.108	1.286ArgHis: 1.286 ± 0.041	3.087ArgIle: 3.087 ± 0.065	2.221ArgLys: 2.221 ± 0.066	5.706ArgLeu: 5.706 ± 0.097	1.564ArgMet: 1.564 ± 0.05	1.82ArgAsn: 1.82 ± 0.06	2.871ArgPro: 2.871 ± 0.07	1.999ArgGln: 1.999 ± 0.053	4.651ArgArg: 4.651 ± 0.12	3.151ArgSer: 3.151 ± 0.069	3.388ArgThr: 3.388 ± 0.07	4.704ArgVal: 4.704 ± 0.084	0.841ArgTrp: 0.841 ± 0.034	1.615ArgTyr: 1.615 ± 0.043	0.0ArgXaa: 0.0 ± 0.0
Ser	6.733SerAla: 6.733 ± 0.101	0.36SerCys: 0.36 ± 0.024	2.899SerAsp: 2.899 ± 0.072	3.406SerGlu: 3.406 ± 0.07	2.037SerPhe: 2.037 ± 0.05	5.47SerGly: 5.47 ± 0.097	1.184SerHis: 1.184 ± 0.043	2.814SerIle: 2.814 ± 0.073	1.923SerLys: 1.923 ± 0.056	5.219SerLeu: 5.219 ± 0.085	1.517SerMet: 1.517 ± 0.048	1.654SerAsn: 1.654 ± 0.049	3.041SerPro: 3.041 ± 0.07	2.124SerGln: 2.124 ± 0.051	3.579SerArg: 3.579 ± 0.076	3.699SerSer: 3.699 ± 0.08	3.668SerThr: 3.668 ± 0.075	4.356SerVal: 4.356 ± 0.078	0.838SerTrp: 0.838 ± 0.038	1.304SerTyr: 1.304 ± 0.043	0.0SerXaa: 0.0 ± 0.0
Thr	6.502ThrAla: 6.502 ± 0.108	0.396ThrCys: 0.396 ± 0.024	3.058ThrAsp: 3.058 ± 0.074	3.264ThrGlu: 3.264 ± 0.069	1.891ThrPhe: 1.891 ± 0.048	5.431ThrGly: 5.431 ± 0.084	1.159ThrHis: 1.159 ± 0.041	2.899ThrIle: 2.899 ± 0.059	1.88ThrLys: 1.88 ± 0.055	5.25ThrLeu: 5.25 ± 0.091	1.287ThrMet: 1.287 ± 0.046	1.705ThrAsn: 1.705 ± 0.05	3.643ThrPro: 3.643 ± 0.085	1.758ThrGln: 1.758 ± 0.051	3.139ThrArg: 3.139 ± 0.074	3.324ThrSer: 3.324 ± 0.069	3.568ThrThr: 3.568 ± 0.082	5.431ThrVal: 5.431 ± 0.103	0.81ThrTrp: 0.81 ± 0.036	1.365ThrTyr: 1.365 ± 0.048	0.0ThrXaa: 0.0 ± 0.0
Val	10.079ValAla: 10.079 ± 0.123	0.668ValCys: 0.668 ± 0.031	5.291ValAsp: 5.291 ± 0.09	5.424ValGlu: 5.424 ± 0.103	2.574ValPhe: 2.574 ± 0.067	6.583ValGly: 6.583 ± 0.115	1.488ValHis: 1.488 ± 0.048	4.573ValIle: 4.573 ± 0.085	2.444ValLys: 2.444 ± 0.058	7.28ValLeu: 7.28 ± 0.115	1.748ValMet: 1.748 ± 0.044	2.471ValAsn: 2.471 ± 0.062	3.901ValPro: 3.901 ± 0.084	1.994ValGln: 1.994 ± 0.051	4.506ValArg: 4.506 ± 0.08	4.742ValSer: 4.742 ± 0.078	5.311ValThr: 5.311 ± 0.107	7.135ValVal: 7.135 ± 0.131	0.998ValTrp: 0.998 ± 0.034	1.677ValTyr: 1.677 ± 0.058	0.0ValXaa: 0.0 ± 0.0
Trp	1.535TrpAla: 1.535 ± 0.046	0.12TrpCys: 0.12 ± 0.014	0.747TrpAsp: 0.747 ± 0.032	0.722TrpGlu: 0.722 ± 0.033	0.53TrpPhe: 0.53 ± 0.03	0.976TrpGly: 0.976 ± 0.041	0.296TrpHis: 0.296 ± 0.018	0.739TrpIle: 0.739 ± 0.034	0.466TrpLys: 0.466 ± 0.026	1.539TrpLeu: 1.539 ± 0.054	0.363TrpMet: 0.363 ± 0.02	0.427TrpAsn: 0.427 ± 0.023	0.671TrpPro: 0.671 ± 0.039	0.489TrpGln: 0.489 ± 0.025	0.848TrpArg: 0.848 ± 0.036	0.743TrpSer: 0.743 ± 0.033	0.733TrpThr: 0.733 ± 0.036	1.047TrpVal: 1.047 ± 0.04	0.308TrpTrp: 0.308 ± 0.022	0.277TrpTyr: 0.277 ± 0.022	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.55TyrAla: 2.55 ± 0.061	0.185TyrCys: 0.185 ± 0.016	1.398TyrAsp: 1.398 ± 0.05	1.394TyrGlu: 1.394 ± 0.045	0.94TyrPhe: 0.94 ± 0.036	2.139TyrGly: 2.139 ± 0.059	0.409TyrHis: 0.409 ± 0.024	0.989TyrIle: 0.989 ± 0.043	0.683TyrLys: 0.683 ± 0.033	2.253TyrLeu: 2.253 ± 0.063	0.441TyrMet: 0.441 ± 0.026	0.68TyrAsn: 0.68 ± 0.035	1.178TyrPro: 1.178 ± 0.036	0.756TyrGln: 0.756 ± 0.03	1.422TyrArg: 1.422 ± 0.047	1.541TyrSer: 1.541 ± 0.05	1.313TyrThr: 1.313 ± 0.042	1.782TyrVal: 1.782 ± 0.054	0.336TyrTrp: 0.336 ± 0.022	0.569TyrTyr: 0.569 ± 0.032	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2172 proteins (717200 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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