Streptomyces clavuligerus

Taxonomy: cellular organisms; Bacteria; Terrabacteria group; Actinobacteria; Actinomycetia; Streptomycetales; Streptomycetaceae; Streptomyces

Average proteome isoelectric point is 6.79

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 7290 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|E2PWC4|E2PWC4_STRCL GntR-family transcriptional regulator OS=Streptomyces clavuligerus OX=1901 GN=SCLAV_0880 PE=4 SV=1
MM1 pKa = 7.2TVQHH5 pKa = 6.41EE6 pKa = 4.4APSDD10 pKa = 3.93GPAEE14 pKa = 4.07ALEE17 pKa = 4.0VWIDD21 pKa = 3.41QDD23 pKa = 3.99LCTGDD28 pKa = 5.01GICAQYY34 pKa = 11.17APDD37 pKa = 4.08VFEE40 pKa = 6.18LDD42 pKa = 3.22IDD44 pKa = 3.57GLAYY48 pKa = 10.51VKK50 pKa = 10.13STDD53 pKa = 4.6DD54 pKa = 4.1EE55 pKa = 4.58LLQEE59 pKa = 4.82PGATAPVPLPLLRR72 pKa = 11.84DD73 pKa = 3.82VVDD76 pKa = 3.94SAKK79 pKa = 10.62DD80 pKa = 3.57CPGDD84 pKa = 4.14CIHH87 pKa = 6.27VRR89 pKa = 11.84RR90 pKa = 11.84VADD93 pKa = 3.62RR94 pKa = 11.84VEE96 pKa = 4.45VYY98 pKa = 10.89GPDD101 pKa = 3.45AEE103 pKa = 4.31

Molecular weight: 11.09 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|B5GY69|B5GY69_STRCL Uncharacterized protein OS=Streptomyces clavuligerus OX=1901 GN=SCLAV_2734 PE=4 SV=1
MM1 pKa = 7.69SKK3 pKa = 9.0RR4 pKa = 11.84TFQPNNRR11 pKa = 11.84RR12 pKa = 11.84RR13 pKa = 11.84AKK15 pKa = 8.7THH17 pKa = 5.15GFRR20 pKa = 11.84LRR22 pKa = 11.84MRR24 pKa = 11.84TRR26 pKa = 11.84AGRR29 pKa = 11.84AILASRR35 pKa = 11.84RR36 pKa = 11.84SKK38 pKa = 10.75GRR40 pKa = 11.84ARR42 pKa = 11.84LSAA45 pKa = 3.91

Molecular weight: 5.28 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

7290

0

7290

2468841

21

6842

338.7

36.11

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

13.594 ± 0.044

0.875 ± 0.01

5.766 ± 0.026

5.529 ± 0.03

2.567 ± 0.016

10.105 ± 0.035

2.357 ± 0.016

2.935 ± 0.02

1.731 ± 0.023

10.083 ± 0.036

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.608 ± 0.013

1.627 ± 0.017

6.935 ± 0.034

2.487 ± 0.017

8.91 ± 0.034

5.037 ± 0.022

6.343 ± 0.032

8.12 ± 0.03

1.478 ± 0.012

1.908 ± 0.012
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski