LI polyomavirus

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Sepolyvirales; Polyomaviridae; Alphapolyomavirus; Human polyomavirus 14

Average proteome isoelectric point is 6.15

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 5 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A1W2KRP8|A0A1W2KRP8_9POLY Minor capsid protein VP2 OS=LI polyomavirus OX=1965344 GN=VP3 PE=3 SV=1
MM1 pKa = 7.59GGFISLVLSVAEE13 pKa = 4.17IATEE17 pKa = 4.26LSAATGFAVDD27 pKa = 5.14AIVSGEE33 pKa = 3.75ALAAIEE39 pKa = 4.68AEE41 pKa = 4.63VASLMTIEE49 pKa = 4.59GLSGAEE55 pKa = 3.89ALAQLGYY62 pKa = 8.71TAEE65 pKa = 4.09QFSNFSLVSSLMNQAIGYY83 pKa = 7.22GTLFQTVTGVSSLVAAGIKK102 pKa = 10.41LSLQDD107 pKa = 3.17RR108 pKa = 11.84SIIVTPLSPGSRR120 pKa = 11.84NNIPGMSSTLTLKK133 pKa = 10.03GHH135 pKa = 6.7PRR137 pKa = 11.84LALEE141 pKa = 5.05FYY143 pKa = 10.47IDD145 pKa = 3.69PLNYY149 pKa = 9.03NHH151 pKa = 6.79SMLNVLGQKK160 pKa = 9.43LWEE163 pKa = 4.91SIAEE167 pKa = 3.98EE168 pKa = 4.39HH169 pKa = 6.07KK170 pKa = 9.93TLGIYY175 pKa = 7.34TNKK178 pKa = 10.35GKK180 pKa = 10.28LLEE183 pKa = 4.05LARR186 pKa = 11.84WEE188 pKa = 4.32VRR190 pKa = 11.84GQNSNNLSGNMVYY203 pKa = 10.26FPPPNGGANQQTCPDD218 pKa = 3.52WLLPLVLGLSGTVTSTWEE236 pKa = 3.86NLQDD240 pKa = 3.91GPQEE244 pKa = 4.01KK245 pKa = 10.67SFF247 pKa = 3.78

Molecular weight: 26.26 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A1U9VWX0|A0A1U9VWX0_9POLY Isoform of A0A1U9VWR9 Small T antigen OS=LI polyomavirus OX=1965344 GN=T PE=4 SV=1
MM1 pKa = 7.84DD2 pKa = 5.27AVLTTPEE9 pKa = 3.9RR10 pKa = 11.84RR11 pKa = 11.84QLCLLLDD18 pKa = 4.19ISPQEE23 pKa = 4.12YY24 pKa = 11.11GNIPLMKK31 pKa = 10.24NAFKK35 pKa = 10.67KK36 pKa = 10.65ACLKK40 pKa = 10.04HH41 pKa = 7.02HH42 pKa = 7.19PDD44 pKa = 3.31KK45 pKa = 11.65GGDD48 pKa = 3.65PVLMMQLNSLWGKK61 pKa = 8.03FTTSLTEE68 pKa = 3.99ARR70 pKa = 11.84ASTYY74 pKa = 9.69QASTLFWEE82 pKa = 4.9IDD84 pKa = 3.55NPLKK88 pKa = 10.94NLLGPVIKK96 pKa = 10.42RR97 pKa = 11.84PFLKK101 pKa = 10.46SPHH104 pKa = 6.64CINSKK109 pKa = 10.28FYY111 pKa = 9.86NCRR114 pKa = 11.84CIVCSLSDD122 pKa = 3.2QHH124 pKa = 8.06SSLKK128 pKa = 10.26ILQKK132 pKa = 10.33KK133 pKa = 9.06KK134 pKa = 9.74CLIWGEE140 pKa = 4.44CYY142 pKa = 10.24CYY144 pKa = 10.88YY145 pKa = 10.95CFVTWFGLPGNSATFEE161 pKa = 4.35DD162 pKa = 4.86YY163 pKa = 11.34KK164 pKa = 11.58NLILEE169 pKa = 4.21MDD171 pKa = 3.42VDD173 pKa = 5.45LLNLHH178 pKa = 6.77CC179 pKa = 5.94

Molecular weight: 20.55 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

4

1

5

1832

171

800

366.4

41.01

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.568 ± 0.889

2.566 ± 0.7

4.694 ± 0.668

6.332 ± 0.707

4.367 ± 0.675

6.496 ± 1.082

1.965 ± 0.206

4.585 ± 0.599

6.55 ± 0.882

10.753 ± 1.335

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.293 ± 0.164

6.332 ± 0.523

6.987 ± 1.011

4.094 ± 0.24

4.039 ± 0.639

7.205 ± 1.164

5.841 ± 0.432

4.967 ± 0.947

1.419 ± 0.236

2.948 ± 0.485
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski