Aplysia californica nido-like virus
Average proteome isoelectric point is 5.57
Get precalculated fractions of proteins
Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
All
Note: above files contain also dissociation constants (pKa)
Virtual 2D-PAGE plot for 3 proteins (isoelectric point calculated using IPC2_protein)
Get csv file with sequences according to given criteria:
* You can choose from 21 different methods for calculating isoelectric point
Summary statistics related to proteome-wise predictions
Protein with the lowest isoelectric point:
>tr|A0A345GNZ4|A0A345GNZ4_9NIDO ORF1ab polyprotein OS=Aplysia californica nido-like virus OX=2283236 PE=4 SV=1
MM1 pKa = 7.56 ANANRR6 pKa = 11.84 KK7 pKa = 8.46 RR8 pKa = 11.84 APEE11 pKa = 4.09 GSVDD15 pKa = 3.68 LGLANVRR22 pKa = 11.84 TLLSQSFEE30 pKa = 4.17 KK31 pKa = 11.15 VKK33 pKa = 10.86 GLTEE37 pKa = 4.16 EE38 pKa = 4.2 EE39 pKa = 4.58 LGDD42 pKa = 3.8 IPSLFTLQLKK52 pKa = 10.97 GEE54 pKa = 4.41 FSSSLGNLGSRR65 pKa = 11.84 LQLYY69 pKa = 10.07 LRR71 pKa = 11.84 AKK73 pKa = 10.11 GIQKK77 pKa = 6.29 TTLRR81 pKa = 11.84 FDD83 pKa = 3.75 VKK85 pKa = 10.35 DD86 pKa = 3.28 TSKK89 pKa = 9.75 TVRR92 pKa = 11.84 VVHH95 pKa = 5.83 VACADD100 pKa = 3.51 VADD103 pKa = 3.98 GHH105 pKa = 6.41 GLDD108 pKa = 4.22 SIRR111 pKa = 11.84 GEE113 pKa = 3.97 TVEE116 pKa = 4.0 YY117 pKa = 11.0 QEE119 pKa = 4.81 DD120 pKa = 4.01 GKK122 pKa = 9.87 PASVVIEE129 pKa = 4.36 GVSHH133 pKa = 7.2 DD134 pKa = 3.75 GEE136 pKa = 4.39 YY137 pKa = 10.61 LQRR140 pKa = 11.84 ICDD143 pKa = 3.5 ACKK146 pKa = 9.67 SAEE149 pKa = 3.96 RR150 pKa = 11.84 MAEE153 pKa = 3.97 EE154 pKa = 4.18 QVQAGQIRR162 pKa = 11.84 FGKK165 pKa = 10.15 LKK167 pKa = 10.55 AHH169 pKa = 7.24 FIEE172 pKa = 4.83 EE173 pKa = 3.93 AAFPFMGLVDD183 pKa = 4.0 RR184 pKa = 11.84 VIHH187 pKa = 5.65 RR188 pKa = 11.84 TLNGIGAIVEE198 pKa = 4.44 FKK200 pKa = 10.36 KK201 pKa = 10.9 GQVVAPQGGEE211 pKa = 3.98 HH212 pKa = 5.89 VKK214 pKa = 10.47 EE215 pKa = 4.32 KK216 pKa = 10.39 SAKK219 pKa = 8.49 EE220 pKa = 3.86 VSVCEE225 pKa = 3.85 QAPVEE230 pKa = 4.26 KK231 pKa = 10.85 GEE233 pKa = 4.09 EE234 pKa = 3.95 ARR236 pKa = 11.84 KK237 pKa = 10.62 GEE239 pKa = 4.15 DD240 pKa = 3.17 QAVVDD245 pKa = 4.04 VQAGVEE251 pKa = 4.27 VQTDD255 pKa = 3.44 VAPPKK260 pKa = 10.2 VEE262 pKa = 3.84 PMYY265 pKa = 10.12 TAEE268 pKa = 5.4 SDD270 pKa = 3.77 DD271 pKa = 4.43 ASLKK275 pKa = 10.09 QVAPPTGEE283 pKa = 3.89 EE284 pKa = 4.03 ASSDD288 pKa = 3.62 EE289 pKa = 4.72 DD290 pKa = 4.62 DD291 pKa = 5.79 DD292 pKa = 5.45 VVLLDD297 pKa = 3.83 TTLALPFTEE306 pKa = 4.48 TDD308 pKa = 3.34 DD309 pKa = 4.29 GAVGLYY315 pKa = 9.67 VPKK318 pKa = 10.74 LSLSLSSLEE327 pKa = 4.21 KK328 pKa = 10.85 EE329 pKa = 4.47 EE330 pKa = 4.35 EE331 pKa = 4.12 ASSDD335 pKa = 3.47 EE336 pKa = 4.43 SDD338 pKa = 3.6 WKK340 pKa = 11.28 SGDD343 pKa = 3.53 PGDD346 pKa = 4.13 QFDD349 pKa = 3.94 HH350 pKa = 7.48 GEE352 pKa = 4.1 EE353 pKa = 4.21 EE354 pKa = 5.16 SLSEE358 pKa = 4.28 WEE360 pKa = 5.09 SDD362 pKa = 3.69 DD363 pKa = 5.51 ADD365 pKa = 3.65 WTEE368 pKa = 4.47 GPVPTEE374 pKa = 3.88 EE375 pKa = 4.29 EE376 pKa = 4.56 TTVHH380 pKa = 6.93 AVLCEE385 pKa = 4.04 VGLKK389 pKa = 9.9 PVSAPKK395 pKa = 10.64 DD396 pKa = 3.41 EE397 pKa = 4.53 GDD399 pKa = 3.5 EE400 pKa = 4.55 GEE402 pKa = 4.6 VPVAAQEE409 pKa = 4.26 EE410 pKa = 4.58 PSGNAKK416 pKa = 10.43 LEE418 pKa = 4.31 SEE420 pKa = 4.71 DD421 pKa = 3.83 VEE423 pKa = 4.54 QVDD426 pKa = 4.29 EE427 pKa = 5.15 GDD429 pKa = 4.29 VEE431 pKa = 5.29 DD432 pKa = 5.21 KK433 pKa = 10.09 PTMPTGEE440 pKa = 4.2 TAEE443 pKa = 4.87 KK444 pKa = 10.04 EE445 pKa = 4.06 DD446 pKa = 4.2 TPADD450 pKa = 4.35 SIWEE454 pKa = 3.93 ASEE457 pKa = 4.16 AKK459 pKa = 9.81 PEE461 pKa = 3.92 KK462 pKa = 9.63 AAKK465 pKa = 10.43 VMTDD469 pKa = 3.06 GSEE472 pKa = 4.65 LFDD475 pKa = 4.98 DD476 pKa = 4.82 PPVVSNLQKK485 pKa = 10.12 MFGGKK490 pKa = 8.46 VAQAPHH496 pKa = 6.45 TLDD499 pKa = 3.74 CLPRR503 pKa = 11.84 PTPMVVVNLGFRR515 pKa = 11.84 DD516 pKa = 3.44 AGEE519 pKa = 4.36 RR520 pKa = 11.84 GPVPVRR526 pKa = 11.84 RR527 pKa = 11.84 VSPPTSSDD535 pKa = 2.75 KK536 pKa = 10.6 RR537 pKa = 11.84 GEE539 pKa = 4.03 YY540 pKa = 10.23 HH541 pKa = 6.79 GVTRR545 pKa = 11.84 KK546 pKa = 6.36 WTFGRR551 pKa = 11.84 EE552 pKa = 4.18 GFSVSSVTPRR562 pKa = 11.84 QTKK565 pKa = 9.65 VEE567 pKa = 4.27 TVGPVGNDD575 pKa = 2.99 VSGNAEE581 pKa = 3.95 NGTPSVVQVSSSIGVLNFAVRR602 pKa = 11.84 AHH604 pKa = 6.71 GLTADD609 pKa = 4.31 EE610 pKa = 4.81 KK611 pKa = 9.58 PLPKK615 pKa = 9.78 RR616 pKa = 11.84 EE617 pKa = 4.14 VKK619 pKa = 10.67 EE620 pKa = 3.72 KK621 pKa = 10.01 DD622 pKa = 3.13 TSVKK626 pKa = 9.86 PKK628 pKa = 10.02 SVEE631 pKa = 3.9 AKK633 pKa = 9.73 RR634 pKa = 11.84 VPPKK638 pKa = 9.96 PRR640 pKa = 11.84 PRR642 pKa = 11.84 KK643 pKa = 8.3 LAKK646 pKa = 9.68 IEE648 pKa = 3.78 RR649 pKa = 11.84 DD650 pKa = 3.41 AAGHH654 pKa = 6.0 LVIGNKK660 pKa = 8.06 QRR662 pKa = 11.84 QPEE665 pKa = 4.07 ATPRR669 pKa = 11.84 VPLNMHH675 pKa = 5.97 VDD677 pKa = 3.66 DD678 pKa = 5.27 GVIHH682 pKa = 6.34 TSVASVEE689 pKa = 4.34 KK690 pKa = 10.9 ADD692 pKa = 4.14 FEE694 pKa = 4.7 YY695 pKa = 10.73 GAPSAHH701 pKa = 6.89 PRR703 pKa = 11.84 RR704 pKa = 11.84 PTKK707 pKa = 10.14 FGIRR711 pKa = 11.84 HH712 pKa = 4.51 WHH714 pKa = 7.07 DD715 pKa = 3.09 KK716 pKa = 11.27 SEE718 pKa = 4.08 WEE720 pKa = 4.38 SMLEE724 pKa = 3.63 PSYY727 pKa = 10.68 FLSLEE732 pKa = 3.97 RR733 pKa = 11.84 VAEE736 pKa = 4.07 HH737 pKa = 6.92 VPGQVHH743 pKa = 5.48 ATSRR747 pKa = 11.84 KK748 pKa = 7.71 QKK750 pKa = 9.71 VVKK753 pKa = 9.22 ATHH756 pKa = 6.12 FDD758 pKa = 3.44 KK759 pKa = 11.32 LFGPNRR765 pKa = 11.84 RR766 pKa = 11.84 DD767 pKa = 3.07 IPLLEE772 pKa = 4.31 DD773 pKa = 3.31 VRR775 pKa = 11.84 CNSEE779 pKa = 3.77 SLRR782 pKa = 11.84 WKK784 pKa = 10.18 KK785 pKa = 10.41 KK786 pKa = 9.23 RR787 pKa = 11.84 LVGEE791 pKa = 4.57 KK792 pKa = 9.93 IRR794 pKa = 11.84 VEE796 pKa = 4.03 RR797 pKa = 11.84 NEE799 pKa = 3.7 APRR802 pKa = 11.84 PSVKK806 pKa = 10.32 FLTTVFLVCCMFCAGSYY823 pKa = 9.76 ISRR826 pKa = 11.84 DD827 pKa = 3.19 EE828 pKa = 4.27 TTTVPGSDD836 pKa = 3.7 LYY838 pKa = 11.44 DD839 pKa = 3.38 VVGRR843 pKa = 11.84 GLKK846 pKa = 10.5 DD847 pKa = 3.33 LMGVLTPILQDD858 pKa = 3.35 CRR860 pKa = 11.84 INSSSFFYY868 pKa = 10.58 NHH870 pKa = 5.52 YY871 pKa = 10.26 HH872 pKa = 6.7 FEE874 pKa = 4.34 YY875 pKa = 10.71 EE876 pKa = 4.37 NTWLLGLLVIPWLKK890 pKa = 10.87 GYY892 pKa = 7.61 LTSLDD897 pKa = 3.32 VCMVLLAIVTTAGIPALALLALICVPQAPRR927 pKa = 11.84 LVYY930 pKa = 10.62 DD931 pKa = 3.52 CLCRR935 pKa = 11.84 VGVRR939 pKa = 11.84 CDD941 pKa = 3.47 LLMAVTDD948 pKa = 3.86 ILIVCADD955 pKa = 3.7 TCLMSFSLMHH965 pKa = 5.98 YY966 pKa = 9.83 FCFPLAFFSTCFRR979 pKa = 11.84 RR980 pKa = 11.84 ITGRR984 pKa = 11.84 NLFSKK989 pKa = 9.65 MRR991 pKa = 11.84 SFLQAILYY999 pKa = 9.51 GKK1001 pKa = 9.42 IQLDD1005 pKa = 3.4 KK1006 pKa = 10.98 DD1007 pKa = 3.97 GEE1009 pKa = 4.34 FATSDD1014 pKa = 3.54 EE1015 pKa = 4.52 GVGQHH1020 pKa = 6.24 GYY1022 pKa = 10.51 YY1023 pKa = 9.53 SAHH1026 pKa = 5.47 VTSEE1030 pKa = 3.96 VTTSEE1035 pKa = 4.57 EE1036 pKa = 4.15 YY1037 pKa = 10.36 TPNTQCEE1044 pKa = 4.16 TAVTDD1049 pKa = 3.41 RR1050 pKa = 11.84 QLFVRR1055 pKa = 11.84 HH1056 pKa = 5.6 SVFGAIRR1063 pKa = 11.84 LSILGRR1069 pKa = 11.84 IPGRR1073 pKa = 11.84 GLVCHH1078 pKa = 6.23 GVRR1081 pKa = 11.84 ASSLYY1086 pKa = 8.86 TASGSLIVADD1096 pKa = 4.34 NIGRR1100 pKa = 11.84 AALSYY1105 pKa = 10.96 AGVVTPNFLGCLAFLSFFFFSMEE1128 pKa = 4.1 SAFVLSFLFFVVDD1141 pKa = 3.59 NLVTQTSDD1149 pKa = 3.16 LVVVNWHH1156 pKa = 7.03 DD1157 pKa = 4.01 SYY1159 pKa = 10.82 VHH1161 pKa = 6.37 KK1162 pKa = 10.83 SVVPAAYY1169 pKa = 7.29 KK1170 pKa = 10.14 TLDD1173 pKa = 3.34 QTSEE1177 pKa = 4.35 DD1178 pKa = 4.25 EE1179 pKa = 4.34 FTASNIHH1186 pKa = 6.42 VLGVWDD1192 pKa = 5.59 LFALTLKK1199 pKa = 10.79 SLFSKK1204 pKa = 10.74 VFTKK1208 pKa = 10.48 AVSMRR1213 pKa = 11.84 FYY1215 pKa = 10.1 TLKK1218 pKa = 10.51 AVYY1221 pKa = 8.6 PICTYY1226 pKa = 10.56 TYY1228 pKa = 10.17 FFDD1231 pKa = 4.71 FFLFLFVLIDD1241 pKa = 3.74 PSAGYY1246 pKa = 10.84 LPMNPKK1252 pKa = 10.2 KK1253 pKa = 10.36 FIRR1256 pKa = 11.84 EE1257 pKa = 3.87 NQYY1260 pKa = 11.6 KK1261 pKa = 8.66 LTEE1264 pKa = 4.03 AARR1267 pKa = 11.84 SSRR1270 pKa = 11.84 LICAKK1275 pKa = 10.01 QIRR1278 pKa = 11.84 LSNTRR1283 pKa = 11.84 RR1284 pKa = 11.84 YY1285 pKa = 8.36 IASRR1289 pKa = 11.84 FGEE1292 pKa = 4.36 QVALALGFSGEE1303 pKa = 4.15 TSKK1306 pKa = 10.89 VARR1309 pKa = 11.84 YY1310 pKa = 9.05 GWDD1313 pKa = 4.18 LIWLLLCQVALLAVFYY1329 pKa = 9.56 FPAVAHH1335 pKa = 6.3 FMFLFPFLFYY1345 pKa = 10.44 IILIRR1350 pKa = 11.84 LVVKK1354 pKa = 10.14 PLTRR1358 pKa = 11.84 VDD1360 pKa = 3.37 LVMRR1364 pKa = 11.84 VVSISSLLPLCYY1376 pKa = 9.28 WGLRR1380 pKa = 11.84 VLGLPTSSWIGGIEE1394 pKa = 3.92 VTVASLCLSLTLVLLFIHH1412 pKa = 5.88 QFFGAIALYY1421 pKa = 9.93 FGWRR1425 pKa = 11.84 SSTHH1429 pKa = 6.13 KK1430 pKa = 10.47 ATDD1433 pKa = 3.84 FVRR1436 pKa = 11.84 KK1437 pKa = 8.75 LQYY1440 pKa = 10.92 VVDD1443 pKa = 4.31 TLPHH1447 pKa = 6.51 HH1448 pKa = 6.96 ILRR1451 pKa = 11.84 SQDD1454 pKa = 3.51 TIAVNAMFKK1463 pKa = 10.5 RR1464 pKa = 11.84 IGEE1467 pKa = 3.97 LRR1469 pKa = 11.84 DD1470 pKa = 3.24 RR1471 pKa = 11.84 VVASPVVEE1479 pKa = 4.25 DD1480 pKa = 3.69 VSEE1483 pKa = 4.47 LEE1485 pKa = 4.24 GLAKK1489 pKa = 10.27 SAEE1492 pKa = 4.29 VQVKK1496 pKa = 9.25 EE1497 pKa = 4.05 LNKK1500 pKa = 10.33 KK1501 pKa = 9.38 VGEE1504 pKa = 4.12 LFVLLPHH1511 pKa = 6.99 FNDD1514 pKa = 3.53 LLSDD1518 pKa = 3.5 VRR1520 pKa = 11.84 GVCKK1524 pKa = 9.82 EE1525 pKa = 3.95 AKK1527 pKa = 9.91 SKK1529 pKa = 10.74 FSSSDD1534 pKa = 2.57 ISSRR1538 pKa = 11.84 IFGGLRR1544 pKa = 11.84 KK1545 pKa = 9.26 IFSFIFCLCNSSYY1558 pKa = 11.34 VGLIFLVFYY1567 pKa = 10.56 ACIMMFGEE1575 pKa = 4.41 VEE1577 pKa = 3.84 GAEE1580 pKa = 4.04 IGFEE1584 pKa = 4.22 LDD1586 pKa = 3.46 VTIGWDD1592 pKa = 3.42 TFSNPLSLLWFLTKK1606 pKa = 10.73 LLLLVVFLLLFAVVVVGQFILSIIRR1631 pKa = 11.84 IIVNRR1636 pKa = 11.84 EE1637 pKa = 3.84 GIRR1640 pKa = 11.84 SLFRR1644 pKa = 11.84 SNGGLGVSFFSFVLLLSLGVASGLNHH1670 pKa = 6.09 QEE1672 pKa = 3.88 LYY1674 pKa = 10.67 AGNVRR1679 pKa = 11.84 AGGFHH1684 pKa = 6.7 HH1685 pKa = 7.33 ASAAMDD1691 pKa = 3.55 VVGVFSYY1698 pKa = 11.27 AMRR1701 pKa = 11.84 GVFVLSLAALAYY1713 pKa = 10.16 YY1714 pKa = 10.29 FMSAFFLVSVFVIHH1728 pKa = 6.37 MGVANLLVSFIFGIPHH1744 pKa = 6.58 IFVSLGFSQGFFFIGLIFLWIWLYY1768 pKa = 7.73 TTANITLFFLRR1779 pKa = 11.84 RR1780 pKa = 11.84 WLNTFPTEE1788 pKa = 3.95 VFRR1791 pKa = 11.84 FTGQDD1796 pKa = 2.75 ISQFWIKK1803 pKa = 10.45 NAVVAWLAFITGDD1816 pKa = 3.31 VVYY1819 pKa = 10.43 DD1820 pKa = 3.36 PRR1822 pKa = 11.84 GFKK1825 pKa = 10.37 KK1826 pKa = 10.38 LAYY1829 pKa = 9.44 NAADD1833 pKa = 3.39 NTVTFGRR1840 pKa = 11.84 DD1841 pKa = 3.27 RR1842 pKa = 11.84 IKK1844 pKa = 10.94 VEE1846 pKa = 3.93 YY1847 pKa = 8.82 EE1848 pKa = 4.05 VCVSCCVPGHH1858 pKa = 5.57 SVCIDD1863 pKa = 3.66 RR1864 pKa = 11.84 GCCKK1868 pKa = 10.53 GKK1870 pKa = 10.39 DD1871 pKa = 3.49 VGYY1874 pKa = 9.91 GAQIVVDD1881 pKa = 3.44 NLFIKK1886 pKa = 10.68 KK1887 pKa = 10.35 LGPRR1891 pKa = 11.84 FLGGVNPEE1899 pKa = 4.44 DD1900 pKa = 3.73 SPDD1903 pKa = 3.54 FVRR1906 pKa = 11.84 AQAEE1910 pKa = 3.97 IKK1912 pKa = 10.35 EE1913 pKa = 4.26 RR1914 pKa = 11.84 EE1915 pKa = 4.05 KK1916 pKa = 11.24 LLASMLTTARR1926 pKa = 11.84 QNEE1929 pKa = 4.55 EE1930 pKa = 3.62 IAKK1933 pKa = 8.26 TGAYY1937 pKa = 9.89 LFEE1940 pKa = 4.69 VGQKK1944 pKa = 9.26 QLNEE1948 pKa = 4.14 EE1949 pKa = 4.49 LNGDD1953 pKa = 3.72 LHH1955 pKa = 6.6 RR1956 pKa = 11.84 QVEE1959 pKa = 4.41 GLKK1962 pKa = 10.73 LRR1964 pKa = 11.84 GKK1966 pKa = 10.13 GIQAEE1971 pKa = 4.44 TEE1973 pKa = 3.7 IFANQTLLDD1982 pKa = 4.12 AAADD1986 pKa = 3.87 SYY1988 pKa = 11.8 DD1989 pKa = 3.87 ALDD1992 pKa = 4.18 IRR1994 pKa = 11.84 PKK1996 pKa = 10.67 GPRR1999 pKa = 11.84 SSTKK2003 pKa = 10.03 IQITPGNFAYY2013 pKa = 9.55 TILRR2017 pKa = 11.84 TNVNDD2022 pKa = 3.64 YY2023 pKa = 10.75 PGLSLATHH2031 pKa = 7.27 RR2032 pKa = 11.84 GNTCFAVEE2040 pKa = 4.53 RR2041 pKa = 11.84 EE2042 pKa = 4.33 SSAPAYY2048 pKa = 10.68 LPVNHH2053 pKa = 7.55 GISQMLSVLDD2063 pKa = 3.64 ATLLARR2069 pKa = 11.84 TSVTILRR2076 pKa = 11.84 ANYY2079 pKa = 8.97 KK2080 pKa = 9.74 QYY2082 pKa = 10.88 TRR2084 pKa = 11.84 TSCVNWDD2091 pKa = 3.51 VEE2093 pKa = 4.6 SLRR2096 pKa = 11.84 GTKK2099 pKa = 9.91 FDD2101 pKa = 3.48 TFAPSVVVGFTCTGRR2116 pKa = 11.84 ADD2118 pKa = 3.84 FDD2120 pKa = 4.5 VEE2122 pKa = 4.34 CATADD2127 pKa = 3.64 YY2128 pKa = 9.12 EE2129 pKa = 4.18 QLINGVEE2136 pKa = 4.02 RR2137 pKa = 11.84 VSLGEE2142 pKa = 3.88 GDD2144 pKa = 4.2 VLVTLDD2150 pKa = 3.3 GFNWKK2155 pKa = 10.07 GYY2157 pKa = 8.93 EE2158 pKa = 3.95 VASAEE2163 pKa = 4.22 GEE2165 pKa = 4.41 DD2166 pKa = 4.55 IVATDD2171 pKa = 3.31 SDD2173 pKa = 3.64 EE2174 pKa = 4.32 DD2175 pKa = 3.51 AEE2177 pKa = 4.31 YY2178 pKa = 10.65 RR2179 pKa = 11.84 VDD2181 pKa = 3.99 EE2182 pKa = 4.6 VGDD2185 pKa = 3.81 DD2186 pKa = 3.79 GRR2188 pKa = 11.84 VTDD2191 pKa = 5.07 AVPNMKK2197 pKa = 9.68 PVAPLLSYY2205 pKa = 11.05 AGALAKK2211 pKa = 10.6 SEE2213 pKa = 4.53 DD2214 pKa = 3.62 NCLVEE2219 pKa = 5.27 DD2220 pKa = 4.01 VVPVRR2225 pKa = 11.84 TLVNMRR2231 pKa = 11.84 DD2232 pKa = 3.57 LARR2235 pKa = 11.84 KK2236 pKa = 9.61 HH2237 pKa = 4.93 NTPPKK2242 pKa = 10.23 FPVAADD2248 pKa = 3.79 AQPKK2252 pKa = 7.12 FQPMAAAKK2260 pKa = 9.26 NFPSSEE2266 pKa = 4.25 SASTGSASGSSTSSIRR2282 pKa = 11.84 RR2283 pKa = 11.84 EE2284 pKa = 4.0 MEE2286 pKa = 3.68 EE2287 pKa = 3.81 EE2288 pKa = 3.39 RR2289 pKa = 11.84 HH2290 pKa = 5.27 RR2291 pKa = 11.84 RR2292 pKa = 11.84 AKK2294 pKa = 9.69 RR2295 pKa = 11.84 RR2296 pKa = 11.84 AWSSDD2301 pKa = 2.96 AADD2304 pKa = 4.49 DD2305 pKa = 4.25 YY2306 pKa = 11.38 YY2307 pKa = 11.69 AAGVAFMEE2315 pKa = 4.44 ATEE2318 pKa = 5.39 DD2319 pKa = 3.31 IDD2321 pKa = 4.83 VDD2323 pKa = 4.05 VQFEE2327 pKa = 4.07 GLRR2330 pKa = 11.84 RR2331 pKa = 11.84 KK2332 pKa = 8.93 SARR2335 pKa = 11.84 SVTMIDD2341 pKa = 3.14 EE2342 pKa = 4.6 CFTPKK2347 pKa = 10.66 DD2348 pKa = 3.31 ADD2350 pKa = 3.79 GVYY2353 pKa = 8.96 LTYY2356 pKa = 10.82 GFCGKK2361 pKa = 7.29 TQEE2364 pKa = 4.65 FKK2366 pKa = 11.03 LSEE2369 pKa = 4.17 CRR2371 pKa = 11.84 PVNLAGLKK2379 pKa = 10.42 ASGFVFAEE2387 pKa = 4.13 KK2388 pKa = 10.51 VLNGFTFHH2396 pKa = 7.29 RR2397 pKa = 11.84 VRR2399 pKa = 11.84 AAGADD2404 pKa = 3.42 MVVVKK2409 pKa = 10.32 IAEE2412 pKa = 4.13 YY2413 pKa = 10.08 VRR2415 pKa = 11.84 RR2416 pKa = 11.84 GGSFGVKK2423 pKa = 9.75 CAFEE2427 pKa = 4.13 KK2428 pKa = 10.02 LTRR2431 pKa = 11.84 HH2432 pKa = 4.84 YY2433 pKa = 10.95 GEE2435 pKa = 3.86 RR2436 pKa = 11.84 FRR2438 pKa = 11.84 RR2439 pKa = 11.84 EE2440 pKa = 3.61 AQKK2443 pKa = 10.81 QGDD2446 pKa = 4.18 VVRR2449 pKa = 11.84 ADD2451 pKa = 4.33 LNLEE2455 pKa = 4.36 PIKK2458 pKa = 10.45 QVEE2461 pKa = 4.31 KK2462 pKa = 10.58 SASFSFKK2469 pKa = 10.57 QVFVCFLICLLFIFPLFAPVLAFSVSVPASGGASEE2504 pKa = 4.54 SEE2506 pKa = 4.05 RR2507 pKa = 11.84 GVKK2510 pKa = 8.79 VCKK2513 pKa = 10.21 HH2514 pKa = 5.43 EE2515 pKa = 4.4 EE2516 pKa = 3.82 NVGFFRR2522 pKa = 11.84 TDD2524 pKa = 2.86 NTEE2527 pKa = 3.49 YY2528 pKa = 10.7 CAPFEE2533 pKa = 4.48 LGEE2536 pKa = 4.2 RR2537 pKa = 11.84 PQYY2540 pKa = 10.52 EE2541 pKa = 4.03 CSKK2544 pKa = 9.31 TLKK2547 pKa = 9.94 KK2548 pKa = 10.6 CIMDD2552 pKa = 3.63 RR2553 pKa = 11.84 PVLVSGLSRR2562 pKa = 11.84 EE2563 pKa = 4.31 EE2564 pKa = 3.82 KK2565 pKa = 10.31 LSRR2568 pKa = 11.84 AKK2570 pKa = 10.58 EE2571 pKa = 4.25 SIHH2574 pKa = 5.95 EE2575 pKa = 4.33 CVDD2578 pKa = 3.11 KK2579 pKa = 11.13 RR2580 pKa = 11.84 SVLLKK2585 pKa = 10.44 RR2586 pKa = 11.84 EE2587 pKa = 4.25 CCVVSDD2593 pKa = 4.47 VEE2595 pKa = 4.26 DD2596 pKa = 4.28 AQVSACFHH2604 pKa = 5.93 VSEE2607 pKa = 5.08 DD2608 pKa = 3.62 VNLLSNCEE2616 pKa = 3.83 TVYY2619 pKa = 10.37 VQNVTGMNDD2628 pKa = 3.21 FFKK2631 pKa = 11.18 YY2632 pKa = 10.24 EE2633 pKa = 4.04 EE2634 pKa = 4.34 LRR2636 pKa = 11.84 FTDD2639 pKa = 4.41 AMSLNTAEE2647 pKa = 4.1 VRR2649 pKa = 11.84 EE2650 pKa = 4.31 VFADD2654 pKa = 3.71 YY2655 pKa = 10.61 CVEE2658 pKa = 4.08 RR2659 pKa = 11.84 PLVVGDD2665 pKa = 3.55 VTIGEE2670 pKa = 4.57 YY2671 pKa = 9.83 IYY2673 pKa = 11.11 ASDD2676 pKa = 4.89 PFPLPAKK2683 pKa = 8.41 EE2684 pKa = 4.13 TVFDD2688 pKa = 4.43 FLSDD2692 pKa = 3.74 LDD2694 pKa = 4.23 DD2695 pKa = 5.3 GEE2697 pKa = 4.74 VEE2699 pKa = 4.22 EE2700 pKa = 4.42 EE2701 pKa = 4.48 TVFDD2705 pKa = 4.08 FLSVNVEE2712 pKa = 4.81 DD2713 pKa = 5.5 DD2714 pKa = 3.89 DD2715 pKa = 4.4 QPEE2718 pKa = 4.65 GEE2720 pKa = 4.46 SPLVEE2725 pKa = 4.89 KK2726 pKa = 10.62 SDD2728 pKa = 3.48 KK2729 pKa = 11.05 DD2730 pKa = 3.68 RR2731 pKa = 11.84 VVVEE2735 pKa = 4.25 DD2736 pKa = 4.07 LRR2738 pKa = 11.84 VEE2740 pKa = 4.52 AFPPATEE2747 pKa = 4.05 EE2748 pKa = 4.26 SEE2750 pKa = 4.41 SVSVNEE2756 pKa = 3.52 VDD2758 pKa = 3.74 HH2759 pKa = 6.86 RR2760 pKa = 11.84 VVDD2763 pKa = 3.86 SPGTLDD2769 pKa = 3.44 EE2770 pKa = 4.9 LKK2772 pKa = 10.51 HH2773 pKa = 5.72 EE2774 pKa = 4.47 RR2775 pKa = 11.84 VSEE2778 pKa = 4.15 DD2779 pKa = 3.35 VVDD2782 pKa = 4.16 VADD2785 pKa = 4.02 SSSVEE2790 pKa = 3.88 ASVEE2794 pKa = 4.13 TDD2796 pKa = 2.97 SSATGEE2802 pKa = 4.32 NVVEE2806 pKa = 4.47 SYY2808 pKa = 11.37 PNVSVEE2814 pKa = 3.89 NGFSVVHH2821 pKa = 6.18 EE2822 pKa = 4.2 EE2823 pKa = 4.31 SPVVVDD2829 pKa = 4.06 VVRR2832 pKa = 11.84 EE2833 pKa = 4.16 SEE2835 pKa = 4.12 EE2836 pKa = 4.12 SDD2838 pKa = 4.23 DD2839 pKa = 3.88 VDD2841 pKa = 4.58 EE2842 pKa = 5.26 SVPDD2846 pKa = 3.5 MKK2848 pKa = 11.09 LYY2850 pKa = 10.57 DD2851 pKa = 4.16 AYY2853 pKa = 11.4 VSALGKK2859 pKa = 10.31 LRR2861 pKa = 11.84 EE2862 pKa = 4.18 EE2863 pKa = 4.74 YY2864 pKa = 10.44 TNQTHH2869 pKa = 6.18 RR2870 pKa = 11.84 FWRR2873 pKa = 11.84 IIQASVRR2880 pKa = 11.84 NYY2882 pKa = 10.66 LVDD2885 pKa = 4.44 LSSPNSVNVVIYY2897 pKa = 7.17 TTADD2901 pKa = 3.04 MSEE2904 pKa = 4.09 TATCFSKK2911 pKa = 11.05 SFLTIVNEE2919 pKa = 4.23 LVGEE2923 pKa = 4.4 TGPIGVLNLDD2933 pKa = 3.49 HH2934 pKa = 7.69 DD2935 pKa = 4.4 VGYY2938 pKa = 10.79 EE2939 pKa = 3.75 NTVQQFEE2946 pKa = 4.61 DD2947 pKa = 3.84 LFTNSSAVVLGIEE2960 pKa = 4.07 NLSGKK2965 pKa = 9.88 SALALHH2971 pKa = 6.47 GFVEE2975 pKa = 4.47 DD2976 pKa = 4.65 FEE2978 pKa = 4.91 PKK2980 pKa = 9.75 RR2981 pKa = 11.84 EE2982 pKa = 4.0 RR2983 pKa = 11.84 FLSVYY2988 pKa = 9.54 IVTVRR2993 pKa = 11.84 SSVIEE2998 pKa = 3.9 VTTAEE3003 pKa = 4.52 EE3004 pKa = 4.29 KK3005 pKa = 10.92 LSSIWGDD3012 pKa = 3.41 LEE3014 pKa = 3.76 EE3015 pKa = 5.03 DD3016 pKa = 3.05 KK3017 pKa = 11.05 RR3018 pKa = 11.84 FPVLSRR3024 pKa = 11.84 LGANSVFYY3032 pKa = 10.89 RR3033 pKa = 11.84 PGKK3036 pKa = 10.45 KK3037 pKa = 10.03 NISCLPKK3044 pKa = 10.54 VGLGTHH3050 pKa = 6.71 AAAAEE3055 pKa = 4.46 LYY3057 pKa = 9.63 PNLNLYY3063 pKa = 10.64 DD3064 pKa = 4.19 FGEE3067 pKa = 4.46 LRR3069 pKa = 11.84 TVDD3072 pKa = 3.95 DD3073 pKa = 4.59 RR3074 pKa = 11.84 EE3075 pKa = 4.39 GSPSLVLYY3083 pKa = 10.61 KK3084 pKa = 10.32 FLSIMAEE3091 pKa = 4.14 EE3092 pKa = 4.75 TPSLPNDD3099 pKa = 3.48 FFFVLRR3105 pKa = 11.84 GCASGRR3111 pKa = 11.84 DD3112 pKa = 3.67 QGLGPCHH3119 pKa = 6.3 IRR3121 pKa = 11.84 FVVPEE3126 pKa = 4.07 EE3127 pKa = 4.03 LLGDD3131 pKa = 4.15 SLPLLTTTANLLSVTVSSRR3150 pKa = 11.84 QNTVANITANTYY3162 pKa = 10.54 DD3163 pKa = 3.5 AVVKK3167 pKa = 10.48 DD3168 pKa = 5.54 FYY3170 pKa = 11.13 SSHH3173 pKa = 6.74 YY3174 pKa = 8.49 YY3175 pKa = 9.05 GARR3178 pKa = 11.84 IFPLHH3183 pKa = 6.53 VDD3185 pKa = 3.52 VAVEE3189 pKa = 4.61 DD3190 pKa = 4.08 LSSMCEE3196 pKa = 3.98 ATGLCADD3203 pKa = 3.79 VVFVSVGVKK3212 pKa = 9.95 PLGEE3216 pKa = 4.43 GVLSSSVEE3224 pKa = 4.2 VIPTMRR3230 pKa = 11.84 TTVIFDD3236 pKa = 3.16 HH3237 pKa = 7.35 RR3238 pKa = 11.84 YY3239 pKa = 8.78 FRR3241 pKa = 11.84 LNYY3244 pKa = 9.97 KK3245 pKa = 9.73 VDD3247 pKa = 3.24 AEE3249 pKa = 4.43 VRR3251 pKa = 11.84 DD3252 pKa = 5.3 GYY3254 pKa = 11.56 CNLYY3258 pKa = 10.57 KK3259 pKa = 10.47 SFPSSVVSVKK3269 pKa = 10.12 MPFCVQPEE3277 pKa = 4.17 VTYY3280 pKa = 11.01 NPEE3283 pKa = 3.48 ITFKK3287 pKa = 11.56 GEE3289 pKa = 3.77 GCDD3292 pKa = 3.72 EE3293 pKa = 3.95 QFHH3296 pKa = 6.49 RR3297 pKa = 11.84 LNTGGVAFFVLNVSRR3312 pKa = 11.84 VRR3314 pKa = 11.84 NSLCAISHH3322 pKa = 5.08 VQLDD3326 pKa = 4.3 LFGGSPTGLRR3336 pKa = 11.84 PGKK3339 pKa = 10.24 EE3340 pKa = 3.79 PFISVGEE3347 pKa = 4.3 HH3348 pKa = 5.59 FRR3350 pKa = 11.84 TMPLRR3355 pKa = 11.84 RR3356 pKa = 11.84 TMHH3359 pKa = 4.74 VTGEE3363 pKa = 4.07 NLTDD3367 pKa = 3.46 SFIIEE3372 pKa = 4.46 NYY3374 pKa = 10.25 NLLRR3378 pKa = 11.84 DD3379 pKa = 4.12 KK3380 pKa = 11.03 FNASAVFFNGANSNHH3395 pKa = 6.57 CALSARR3401 pKa = 11.84 PFCIPPAYY3409 pKa = 10.22 NVGDD3413 pKa = 3.83 GNVLGKK3419 pKa = 10.31 NLVGAVGIQRR3429 pKa = 11.84 TTAYY3433 pKa = 9.55 FAKK3436 pKa = 10.52 AHH3438 pKa = 6.59 FDD3440 pKa = 3.35 FDD3442 pKa = 3.99 GKK3444 pKa = 10.26 VWYY3447 pKa = 6.76 TACGEE3452 pKa = 4.29 EE3453 pKa = 4.27 EE3454 pKa = 5.12 LDD3456 pKa = 3.65 TASFRR3461 pKa = 11.84 HH3462 pKa = 5.02 SVEE3465 pKa = 4.08 RR3466 pKa = 11.84 EE3467 pKa = 3.88 LPLDD3471 pKa = 4.03 DD3472 pKa = 5.04 LLVRR3476 pKa = 11.84 TRR3478 pKa = 11.84 TGFSQLDD3485 pKa = 3.54 VNLDD3489 pKa = 3.54 VLFQNSTNFTQIMSKK3504 pKa = 11.06 LEE3506 pKa = 3.5 ISEE3509 pKa = 4.12 ATRR3512 pKa = 11.84 HH3513 pKa = 4.34 VVQLEE3518 pKa = 3.89 MAAVEE3523 pKa = 4.62 KK3524 pKa = 10.47 KK3525 pKa = 10.64 VKK3527 pKa = 10.37 ASPLFFVEE3535 pKa = 4.27 YY3536 pKa = 10.06 RR3537 pKa = 11.84 EE3538 pKa = 4.67 HH3539 pKa = 5.34 EE3540 pKa = 4.2 HH3541 pKa = 6.27 SRR3543 pKa = 11.84 TIAKK3547 pKa = 10.03 VEE3549 pKa = 3.73 IFGFSLLKK3557 pKa = 10.23 FLNIGLNKK3565 pKa = 8.55 KK3566 pKa = 8.78 TYY3568 pKa = 10.71 VCDD3571 pKa = 3.94 LCNDD3575 pKa = 3.25 ACDD3578 pKa = 3.32 QYY3580 pKa = 11.88 AYY3582 pKa = 11.14 LEE3584 pKa = 4.16 ATVNIITDD3592 pKa = 3.65 IRR3594 pKa = 11.84 CLHH3597 pKa = 6.08 KK3598 pKa = 11.12 AEE3600 pKa = 4.29 TGVLNSLVSTGNSLFNVEE3618 pKa = 3.89 RR3619 pKa = 11.84 VVFILHH3625 pKa = 7.07 KK3626 pKa = 8.32 STCHH3630 pKa = 5.1 VSVSEE3635 pKa = 4.36 VLDD3638 pKa = 3.24 LHH3640 pKa = 6.94 AARR3643 pKa = 11.84 TMGSISLRR3651 pKa = 11.84 FWQSLFMSKK3660 pKa = 10.08 KK3661 pKa = 9.91 RR3662 pKa = 11.84 VVNLDD3667 pKa = 3.41 TMKK3670 pKa = 10.47 EE3671 pKa = 4.02 PHH3673 pKa = 5.98 IHH3675 pKa = 7.05 AKK3677 pKa = 10.07 NSWRR3681 pKa = 11.84 GNVVLDD3687 pKa = 3.4 VRR3689 pKa = 11.84 TLQEE3693 pKa = 3.99 SVSAFNLGHH3702 pKa = 6.1 YY3703 pKa = 7.91 FYY3705 pKa = 10.72 PPLQKK3710 pKa = 10.41 SAATLYY3716 pKa = 10.57 DD3717 pKa = 3.47 EE3718 pKa = 5.1 CEE3720 pKa = 4.24 AMCGDD3725 pKa = 4.27 CVGFMIVGNDD3735 pKa = 3.13 CKK3737 pKa = 10.85 LFFSEE3742 pKa = 5.36 GVGNYY3747 pKa = 8.74 SVEE3750 pKa = 4.5 AIAHH3754 pKa = 5.22 FVVNQTLGLNADD3766 pKa = 3.89 KK3767 pKa = 10.85 PGLVYY3772 pKa = 10.4 SYY3774 pKa = 10.32 SISGSLITFSINYY3787 pKa = 7.45 LTTTVNVTLTVVDD3800 pKa = 4.51 GKK3802 pKa = 11.16 FKK3804 pKa = 10.82 FISGLMEE3811 pKa = 4.6 LKK3813 pKa = 10.11 VASYY3817 pKa = 10.2 LWEE3820 pKa = 4.44 GLHH3823 pKa = 5.29 PHH3825 pKa = 6.27 YY3826 pKa = 9.41 MGSMFSTVQGLLGRR3840 pKa = 11.84 TSCDD3844 pKa = 3.15 DD3845 pKa = 3.34 AMTEE3849 pKa = 3.53 IALPYY3854 pKa = 9.62 EE3855 pKa = 4.52 GVVLLPTDD3863 pKa = 3.57 SLTDD3867 pKa = 3.75 FTVLDD3872 pKa = 4.5 CLSSRR3877 pKa = 11.84 YY3878 pKa = 9.56 SYY3880 pKa = 11.32 SVVSFHH3886 pKa = 6.83 SFASILRR3893 pKa = 11.84 KK3894 pKa = 9.88 SSTVKK3899 pKa = 10.73 GEE3901 pKa = 3.96 KK3902 pKa = 10.44 LLVSVDD3908 pKa = 2.94 IGSTFEE3914 pKa = 3.44 GWAPKK3919 pKa = 10.15 DD3920 pKa = 3.69 CYY3922 pKa = 10.95 DD3923 pKa = 4.14 WYY3925 pKa = 10.33 PLLEE3929 pKa = 4.03 QEE3931 pKa = 4.53 VVNIHH3936 pKa = 6.46 RR3937 pKa = 11.84 VADD3940 pKa = 3.64 MLNACGNLEE3949 pKa = 3.99 RR3950 pKa = 11.84 PATVLSYY3957 pKa = 11.54 VSGFLNTPVFPDD3969 pKa = 3.3 QFVKK3973 pKa = 10.22 TDD3975 pKa = 3.2 VFKK3978 pKa = 11.13 EE3979 pKa = 4.14 VFKK3982 pKa = 11.27 GMGSIVGEE3990 pKa = 3.91 RR3991 pKa = 11.84 FVLTVTLFQYY4001 pKa = 11.26 SNTDD4005 pKa = 2.91 SAGRR4009 pKa = 11.84 IAYY4012 pKa = 9.76 APVSGPMYY4020 pKa = 10.26 QNSFTYY4026 pKa = 10.01 RR4027 pKa = 11.84 GTFLEE4032 pKa = 4.6 VVSTAEE4038 pKa = 3.72 ADD4040 pKa = 3.71 LPLFGNAFSVEE4051 pKa = 4.11 LGSNAGRR4058 pKa = 11.84 FRR4060 pKa = 11.84 NYY4062 pKa = 10.37 EE4063 pKa = 3.77 LGRR4066 pKa = 11.84 PKK4068 pKa = 10.85 LFGGPLRR4075 pKa = 11.84 FEE4077 pKa = 4.83 DD4078 pKa = 4.08 YY4079 pKa = 11.01 GRR4081 pKa = 11.84 EE4082 pKa = 3.85 LYY4084 pKa = 10.74 QFFLFPWGTGKK4095 pKa = 9.97 NALVIPNVVKK4105 pKa = 10.31 CVPRR4109 pKa = 11.84 NDD4111 pKa = 3.07 ISIVIAEE4118 pKa = 4.19 TDD4120 pKa = 3.7 VFDD4123 pKa = 5.35 LRR4125 pKa = 11.84 PFASGGGRR4133 pKa = 11.84 FDD4135 pKa = 4.81 LFVNGEE4141 pKa = 3.93 IVAGCKK4147 pKa = 9.59 VAGTFDD4153 pKa = 3.71 FLSDD4157 pKa = 4.3 KK4158 pKa = 10.75 IQVVQQHH4165 pKa = 4.95 VFEE4168 pKa = 4.45 HH4169 pKa = 6.04 VGLNFGVSTSSANFILLVLILIFMLIYY4196 pKa = 10.46 IKK4198 pKa = 10.4 MKK4200 pKa = 9.67 FNKK4203 pKa = 9.25 VRR4205 pKa = 11.84 DD4206 pKa = 3.47 LSIFVLYY4213 pKa = 9.07 ATFACVLTLLFSLVDD4228 pKa = 3.72 FGGTLVIVFFLDD4240 pKa = 4.11 IIFTLLIVFTSLSVGGVEE4258 pKa = 5.29 HH4259 pKa = 7.14 FFGCVWLLRR4268 pKa = 11.84 IILLYY4273 pKa = 10.82 NGLFVYY4279 pKa = 9.84 LFVLFLFLRR4288 pKa = 11.84 MILSTIIRR4296 pKa = 11.84 FSIVRR4301 pKa = 11.84 VPLAYY4306 pKa = 10.68 LLRR4309 pKa = 11.84 YY4310 pKa = 6.95 TWYY4313 pKa = 10.49 LFCIPPWKK4321 pKa = 8.72 YY4322 pKa = 7.22 THH4324 pKa = 6.29 LVSVEE4329 pKa = 3.73 EE4330 pKa = 4.87 AYY4332 pKa = 11.02 LHH4334 pKa = 6.66 LPLISLDD4341 pKa = 3.89 DD4342 pKa = 3.97 NAMLSYY4348 pKa = 10.96 GHH4350 pKa = 6.48 VCSTCINKK4358 pKa = 10.14 DD4359 pKa = 2.81 EE4360 pKa = 4.67 STFFWATTTGGRR4372 pKa = 11.84 KK4373 pKa = 9.21 NEE4375 pKa = 4.02 AMLEE4379 pKa = 4.19 SQRR4382 pKa = 11.84 GKK4384 pKa = 10.6 RR4385 pKa = 11.84 VLQSDD4390 pKa = 4.04 ANLFSDD4396 pKa = 3.82 VFGSLVTVSYY4406 pKa = 11.09 GSSTSVNMNGVIVSMFTIVVPRR4428 pKa = 11.84 HH4429 pKa = 5.57 LFLTSGNTQAYY4440 pKa = 9.43 AAMEE4444 pKa = 4.05 RR4445 pKa = 11.84 DD4446 pKa = 3.43 IAALASKK4453 pKa = 10.94 GEE4455 pKa = 4.08 LSITLNKK4462 pKa = 9.1 KK4463 pKa = 5.63 TVKK4466 pKa = 9.82 VSNVVFVGCLAYY4478 pKa = 8.99 ITFDD4482 pKa = 3.54 SHH4484 pKa = 6.85 VGRR4487 pKa = 11.84 PLGYY4491 pKa = 10.29 EE4492 pKa = 4.22 KK4493 pKa = 10.45 ISLDD4497 pKa = 3.43 SAFKK4501 pKa = 10.55 NRR4503 pKa = 11.84 PDD4505 pKa = 3.68 VQVGAAINYY4514 pKa = 8.53 RR4515 pKa = 11.84 SGVTPVVIGNNGTVYY4530 pKa = 10.62 GALEE4534 pKa = 4.64 GGDD4537 pKa = 3.83 CGTPLFVYY4545 pKa = 10.21 DD4546 pKa = 3.14 GHH4548 pKa = 5.53 GWRR4551 pKa = 11.84 WLGVHH4556 pKa = 5.31 NTGINANVVDD4566 pKa = 4.51 GQTFPVNVFLDD4577 pKa = 3.34 ITTGVSQHH4585 pKa = 5.62 GKK4587 pKa = 9.48 IDD4589 pKa = 3.57 QSDD4592 pKa = 3.79 VKK4594 pKa = 10.3 IGPFRR4599 pKa = 11.84 VPIMGAMVKK4608 pKa = 10.76 ALMKK4612 pKa = 10.36 KK4613 pKa = 9.09 VLPGEE4618 pKa = 4.29 FLNDD4622 pKa = 2.96 ATKK4625 pKa = 10.57 IFLCDD4630 pKa = 3.52 DD4631 pKa = 3.59 TSLLLQYY4638 pKa = 10.23 DD4639 pKa = 3.72 GHH4641 pKa = 7.71 VLAEE4645 pKa = 4.11 EE4646 pKa = 4.34 YY4647 pKa = 10.76 KK4648 pKa = 10.28 RR4649 pKa = 11.84 VSDD4652 pKa = 3.57 MTSIGLNFSTAVFEE4666 pKa = 4.89 SIGGNEE4672 pKa = 4.62 GIVLHH4677 pKa = 6.41 TSDD4680 pKa = 4.44 GPVVLDD4686 pKa = 3.89 EE4687 pKa = 4.81 KK4688 pKa = 11.08 KK4689 pKa = 9.99 GTTALIPLLLCCLCTLLFVFPLPAMLTWFVFFTVFCVSVYY4729 pKa = 10.56 HH4730 pKa = 6.86 CVGFYY4735 pKa = 9.58 NTVFVVSGEE4744 pKa = 4.03 LVFFVLRR4751 pKa = 11.84 LFFYY4755 pKa = 10.26 QLSYY4759 pKa = 10.79 TVDD4762 pKa = 2.71 NDD4764 pKa = 3.25 MFVRR4768 pKa = 11.84 VVFILVVCMTLWEE4781 pKa = 4.17 IVRR4784 pKa = 11.84 YY4785 pKa = 9.82 RR4786 pKa = 11.84 SFDD4789 pKa = 3.89 FILFLLVAGVMASMFCLYY4807 pKa = 10.62 SLTYY4811 pKa = 10.35 GYY4813 pKa = 11.53 YY4814 pKa = 10.71 LFANLLMMDD4823 pKa = 4.49 PLSFVLFSNAHH4834 pKa = 6.02 FGLFSFGATGYY4845 pKa = 10.82 RR4846 pKa = 11.84 FFNRR4850 pKa = 11.84 LDD4852 pKa = 3.23 MLKK4855 pKa = 10.2 YY4856 pKa = 10.26 FLYY4859 pKa = 10.8 DD4860 pKa = 3.86 GIFVIRR4866 pKa = 11.84 VYY4868 pKa = 10.7 TFLATGEE4875 pKa = 4.37 LNYY4878 pKa = 10.26 IHH4880 pKa = 5.75 YY4881 pKa = 8.92 TVYY4884 pKa = 11.08 NEE4886 pKa = 4.96 DD4887 pKa = 3.15 GTIFDD4892 pKa = 5.17 MLSKK4896 pKa = 10.21 WLGLSVEE4903 pKa = 4.32 PEE4905 pKa = 4.15 YY4906 pKa = 11.31 DD4907 pKa = 3.08 PSNQVKK4913 pKa = 10.35 NEE4915 pKa = 3.92 SATVPGKK4922 pKa = 9.94 ILKK4925 pKa = 10.48 GGVSNLVYY4933 pKa = 10.65 SILGEE4938 pKa = 4.01 LVEE4941 pKa = 4.24 LAEE4944 pKa = 4.73 GVGSHH4949 pKa = 6.5 VDD4951 pKa = 3.16 TAILVRR4957 pKa = 11.84 AQQAYY4962 pKa = 10.04 NDD4964 pKa = 4.25 SEE4966 pKa = 5.12 RR4967 pKa = 11.84 KK4968 pKa = 8.87 MEE4970 pKa = 4.54 DD4971 pKa = 2.91 AVNSIIEE4978 pKa = 4.13 LSGALHH4984 pKa = 6.5 SLLPSSVLAGTEE4996 pKa = 4.18 EE4997 pKa = 4.24 NVVAAVGLHH5006 pKa = 5.3 FVRR5009 pKa = 11.84 ANEE5012 pKa = 4.19 GEE5014 pKa = 4.09 RR5015 pKa = 11.84 EE5016 pKa = 4.05 RR5017 pKa = 11.84 LVDD5020 pKa = 4.69 DD5021 pKa = 4.36 YY5022 pKa = 10.92 STKK5025 pKa = 10.8 LIRR5028 pKa = 11.84 GILNARR5034 pKa = 11.84 IFAAAVGSDD5043 pKa = 3.54 RR5044 pKa = 11.84 NPDD5047 pKa = 3.75 KK5048 pKa = 10.6 ITGQVRR5054 pKa = 11.84 EE5055 pKa = 4.44 LLNVIRR5061 pKa = 11.84 TDD5063 pKa = 2.98 TRR5065 pKa = 11.84 GIQEE5069 pKa = 4.2 QINSYY5074 pKa = 10.3 SAAEE5078 pKa = 4.01 FKK5080 pKa = 10.56 KK5081 pKa = 10.78 VYY5083 pKa = 10.45 NSNFTNGSEE5092 pKa = 3.89 VDD5094 pKa = 3.98 FANMLNAVRR5103 pKa = 11.84 RR5104 pKa = 11.84 SARR5107 pKa = 11.84 VKK5109 pKa = 10.67 YY5110 pKa = 10.53 DD5111 pKa = 3.6 DD5112 pKa = 3.3 VLKK5115 pKa = 10.56 RR5116 pKa = 11.84 VKK5118 pKa = 10.49 DD5119 pKa = 4.31 FNRR5122 pKa = 11.84 APQPTLVYY5130 pKa = 10.36 ACSLMDD5136 pKa = 3.92 GLVAALEE5143 pKa = 3.98 QFAPNEE5149 pKa = 4.34 TPSNEE5154 pKa = 3.94 AEE5156 pKa = 3.73 ITDD5159 pKa = 3.91 FVKK5162 pKa = 10.76 KK5163 pKa = 10.11 VGQVIAAEE5171 pKa = 4.07 NFGDD5175 pKa = 4.23 IDD5177 pKa = 4.56 LNSLGEE5183 pKa = 4.15 LDD5185 pKa = 5.33 HH5186 pKa = 7.09 IDD5188 pKa = 3.59 SAIAAVDD5195 pKa = 4.35 LKK5197 pKa = 11.58 SSMTTSKK5204 pKa = 11.2 AEE5206 pKa = 3.83 KK5207 pKa = 8.75 TSCNRR5212 pKa = 11.84 VRR5214 pKa = 11.84 GSLLEE5219 pKa = 4.13 LRR5221 pKa = 11.84 AKK5223 pKa = 8.85 VAKK5226 pKa = 10.04 VYY5228 pKa = 10.69 NIRR5231 pKa = 11.84 DD5232 pKa = 3.65 QAEE5235 pKa = 4.02 KK5236 pKa = 9.71 QAKK5239 pKa = 9.32 AKK5241 pKa = 9.96 RR5242 pKa = 11.84 DD5243 pKa = 3.08 KK5244 pKa = 11.42 DD5245 pKa = 3.45 MQKK5248 pKa = 10.75 AYY5250 pKa = 9.21 EE5251 pKa = 4.03 QEE5253 pKa = 3.58 KK5254 pKa = 10.36 AAAKK5258 pKa = 7.36 EE5259 pKa = 4.03 HH5260 pKa = 7.03 RR5261 pKa = 11.84 DD5262 pKa = 3.03 AAQRR5266 pKa = 11.84 KK5267 pKa = 6.56 QRR5269 pKa = 11.84 VTRR5272 pKa = 11.84 VVARR5276 pKa = 11.84 LFNTIPIYY5284 pKa = 10.72 KK5285 pKa = 9.96 SAGLNAAQFYY5295 pKa = 11.06 SLLTGHH5301 pKa = 6.45 FTPTEE5306 pKa = 3.89 NKK5308 pKa = 10.02 KK5309 pKa = 10.77 VINTLFGDD5317 pKa = 3.94 KK5318 pKa = 10.35 YY5319 pKa = 11.28 INDD5322 pKa = 3.7 FCFDD5326 pKa = 4.6 SIFKK5330 pKa = 10.34 KK5331 pKa = 11.03 YY5332 pKa = 8.91 NTISDD5337 pKa = 3.79 FNEE5340 pKa = 3.9 PEE5342 pKa = 3.63 FEE5344 pKa = 4.34 YY5345 pKa = 11.16 NADD5348 pKa = 3.54 SRR5350 pKa = 11.84 IHH5352 pKa = 6.78 LVQCYY5357 pKa = 10.03 SPNEE5361 pKa = 3.95 QGDD5364 pKa = 3.92 FVPTHH5369 pKa = 5.98 VMTGLGCQDD5378 pKa = 4.79 LPPGLTVYY5386 pKa = 10.62 ALKK5389 pKa = 9.27 TASGVTFVEE5398 pKa = 5.51 GILKK5402 pKa = 10.36 AFNEE5406 pKa = 4.03 NSEE5409 pKa = 4.07 GVLYY5413 pKa = 7.47 FTQQKK5418 pKa = 10.44 NEE5420 pKa = 4.0 GFFSSSGIHH5429 pKa = 5.48 TPCGQPLTCCGEE5441 pKa = 4.18 GTHH5444 pKa = 7.25 DD5445 pKa = 3.77 FTGKK5449 pKa = 10.43 CGGLSEE5455 pKa = 5.71 RR5456 pKa = 11.84 EE5457 pKa = 4.23 LKK5459 pKa = 10.91 LHH5461 pKa = 5.45 VQGCGKK5467 pKa = 10.06 CADD5470 pKa = 3.56 IIKK5473 pKa = 10.34 RR5474 pKa = 11.84 GSHH5477 pKa = 5.83 FNCGRR5482 pKa = 11.84 SSICRR5487 pKa = 11.84 KK5488 pKa = 9.7 KK5489 pKa = 10.84 DD5490 pKa = 3.33 SLSSLEE5496 pKa = 4.23 HH5497 pKa = 5.95 SHH5499 pKa = 6.58 TLNCCIYY5506 pKa = 11.22 AMQNCRR5512 pKa = 11.84 ACQLCNVCGGHH5523 pKa = 6.29 PRR5525 pKa = 11.84 AVGDD5529 pKa = 3.7 QQACTSSMFHH5539 pKa = 6.55 GRR5541 pKa = 11.84 RR5542 pKa = 11.84 CVVTDD5547 pKa = 4.69 CEE5549 pKa = 4.63 GCPLDD5554 pKa = 5.76 HH5555 pKa = 6.69 VPKK5558 pKa = 10.18 YY5559 pKa = 10.63 NNEE5562 pKa = 3.75 AFVGNKK5568 pKa = 9.57 GYY5570 pKa = 10.71 AIKK5573 pKa = 10.78 DD5574 pKa = 3.44 KK5575 pKa = 11.07 ISFEE5579 pKa = 4.32 KK5580 pKa = 10.45 VDD5582 pKa = 4.17 KK5583 pKa = 11.11 NLNCYY5588 pKa = 10.34 AIIHH5592 pKa = 6.1 NGSKK5596 pKa = 10.13 VGYY5599 pKa = 9.95 VGTNYY5604 pKa = 9.58 PDD5606 pKa = 3.37 KK5607 pKa = 11.3 NFVEE5611 pKa = 4.94 VALHH5615 pKa = 6.66 AYY5617 pKa = 8.32 VHH5619 pKa = 5.23 STKK5622 pKa = 10.47 LQQHH5626 pKa = 6.56 PNVKK5630 pKa = 9.11 IWLSRR5635 pKa = 11.84 AFHH5638 pKa = 6.23 AQNKK5642 pKa = 6.34 VWASFICRR5650 pKa = 11.84 VFDD5653 pKa = 3.49 HH5654 pKa = 6.44 YY5655 pKa = 10.67 IARR5658 pKa = 11.84 GSAMLSVQNEE5668 pKa = 4.22 SAGNEE5673 pKa = 4.07 SCRR5676 pKa = 11.84 VKK5678 pKa = 10.65 CIHH5681 pKa = 6.41 NNVLGDD5687 pKa = 3.77 CCLNLLWQGHH5697 pKa = 5.33 TGHH5700 pKa = 6.5 LHH5702 pKa = 4.04 EE5703 pKa = 5.11 HH5704 pKa = 6.6 FARR5707 pKa = 11.84 EE5708 pKa = 4.07 GSDD5711 pKa = 3.64 EE5712 pKa = 4.82 LFLACVAGLDD5722 pKa = 3.52 IRR5724 pKa = 11.84 HH5725 pKa = 6.02 LVFDD5729 pKa = 4.75 RR5730 pKa = 11.84 KK5731 pKa = 10.31 CYY5733 pKa = 10.32 CDD5735 pKa = 3.58 TVLKK5739 pKa = 10.53 ACKK5742 pKa = 9.58 NCVIRR5747 pKa = 11.84 TSVDD5751 pKa = 2.66 KK5752 pKa = 10.88 HH5753 pKa = 5.08 VRR5755 pKa = 11.84 AVYY5758 pKa = 10.41 ARR5760 pKa = 11.84 LFQAYY5765 pKa = 9.05 EE5766 pKa = 3.85 SGAITKK5772 pKa = 9.82 VGKK5775 pKa = 10.26 CDD5777 pKa = 3.23 EE5778 pKa = 4.69 CSNPTVFDD5786 pKa = 3.44 RR5787 pKa = 11.84 CFVCEE5792 pKa = 3.84 HH5793 pKa = 6.89 DD5794 pKa = 4.62 RR5795 pKa = 11.84 YY5796 pKa = 10.85 ASEE5799 pKa = 4.49 GKK5801 pKa = 9.89 IGPKK5805 pKa = 9.77 RR5806 pKa = 11.84 PRR5808 pKa = 11.84 ATANPFDD5815 pKa = 3.88 IKK5817 pKa = 11.15
Molecular weight: 645.36 kDa
Isoelectric point according different methods:
IPC2.protein.svr19 5.352
IPC2_protein 5.372
IPC_protein 5.397
Toseland 5.575
ProMoST 5.639
Dawson 5.525
Bjellqvist 5.601
Wikipedia 5.461
Rodwell 5.474
Grimsley 5.614
Solomon 5.525
Lehninger 5.499
Nozaki 5.728
DTASelect 5.893
Thurlkill 5.753
EMBOSS 5.715
Sillero 5.817
Patrickios 3.923
IPC_peptide 5.537
IPC2_peptide 5.817
IPC2.peptide.svr19 5.762
Protein with the highest isoelectric point:
>tr|A0A345GNZ5|A0A345GNZ5_9NIDO Non-structural protein 6 OS=Aplysia californica nido-like virus OX=2283236 PE=4 SV=1
MM1 pKa = 7.15 HH2 pKa = 7.45 RR3 pKa = 11.84 CFVFLCVFLCLLGSAFSAGHH23 pKa = 5.89 EE24 pKa = 4.27 VDD26 pKa = 5.73 DD27 pKa = 5.17 SGGSCGTLTSTISEE41 pKa = 3.75 RR42 pKa = 11.84 MVRR45 pKa = 11.84 YY46 pKa = 9.15 EE47 pKa = 3.92 YY48 pKa = 10.32 VAKK51 pKa = 10.6 VHH53 pKa = 5.11 STVYY57 pKa = 9.69 FSRR60 pKa = 11.84 VGEE63 pKa = 4.25 VKK65 pKa = 10.7 SFDD68 pKa = 3.87 PGEE71 pKa = 4.36 HH72 pKa = 5.81 GTWEE76 pKa = 4.5 FPLDD80 pKa = 4.11 HH81 pKa = 8.04 PDD83 pKa = 3.2 PMQYY87 pKa = 10.2 IVTGDD92 pKa = 3.52 SCSVTLRR99 pKa = 11.84 THH101 pKa = 5.43 YY102 pKa = 10.33 RR103 pKa = 11.84 RR104 pKa = 11.84 NCYY107 pKa = 9.57 FYY109 pKa = 10.77 AICRR113 pKa = 11.84 EE114 pKa = 4.0 NATAADD120 pKa = 3.91 NLFLAFFITMIVILMCSIFKK140 pKa = 10.77 CMSTMFSRR148 pKa = 11.84 TTVKK152 pKa = 10.47 VDD154 pKa = 2.98 VGEE157 pKa = 4.2 VKK159 pKa = 10.53 KK160 pKa = 11.07 AFTKK164 pKa = 10.85 LDD166 pKa = 3.68 LTPNAVPPQEE176 pKa = 4.41 GCVVTPGEE184 pKa = 4.23 SKK186 pKa = 10.84 AYY188 pKa = 10.07 VPSSQPQVCPSVSRR202 pKa = 11.84 GLSSGVVFCVALCLLSACCLSGVRR226 pKa = 11.84 SFALRR231 pKa = 11.84 SDD233 pKa = 3.85 DD234 pKa = 3.94 NEE236 pKa = 4.25 VVSGGRR242 pKa = 11.84 YY243 pKa = 6.32 EE244 pKa = 4.86 HH245 pKa = 6.94 VSEE248 pKa = 4.57 DD249 pKa = 3.85 TPDD252 pKa = 3.17 VRR254 pKa = 11.84 FLVEE258 pKa = 3.67 GATYY262 pKa = 10.03 EE263 pKa = 4.52 SNVKK267 pKa = 10.01 FADD270 pKa = 3.61 VVGSIISFTDD280 pKa = 4.32 GLCSGVLVGEE290 pKa = 4.18 NLVLTAAHH298 pKa = 6.57 CLVQPAQVLRR308 pKa = 11.84 FCLGDD313 pKa = 3.43 DD314 pKa = 4.51 CYY316 pKa = 11.23 QILSYY321 pKa = 10.87 EE322 pKa = 4.31 VVDD325 pKa = 5.34 KK326 pKa = 11.11 EE327 pKa = 4.07 FTKK330 pKa = 10.55 IGGNDD335 pKa = 3.24 LGLAVIDD342 pKa = 4.17 AKK344 pKa = 11.0 LDD346 pKa = 3.33 NFVRR350 pKa = 11.84 VLPTNAAMSSCYY362 pKa = 9.93 FFGYY366 pKa = 10.35 GGPTDD371 pKa = 3.77 SGLSRR376 pKa = 11.84 TLGSFAVTPFMCSYY390 pKa = 10.22 EE391 pKa = 4.63 GEE393 pKa = 4.3 VLDD396 pKa = 5.25 NLVCSSYY403 pKa = 9.56 EE404 pKa = 3.69 TDD406 pKa = 3.41 GARR409 pKa = 11.84 LCGGDD414 pKa = 2.99 SGGPLICDD422 pKa = 3.88 SPWGLGVYY430 pKa = 10.1 AVASAGGGCSGGSTISMYY448 pKa = 10.75 VDD450 pKa = 3.0 VRR452 pKa = 11.84 RR453 pKa = 11.84 DD454 pKa = 3.61 YY455 pKa = 11.15 PLLRR459 pKa = 11.84 AQVCDD464 pKa = 3.35 SLTVPRR470 pKa = 11.84 SLHH473 pKa = 5.58 LASTEE478 pKa = 3.81 MDD480 pKa = 3.42 VLNITEE486 pKa = 4.44 ADD488 pKa = 3.8 SLFTNATPVKK498 pKa = 10.59 SNFSCASVSPEE509 pKa = 3.76 LLGPLVSGHH518 pKa = 6.3 ASVYY522 pKa = 9.59 TVDD525 pKa = 2.96 SRR527 pKa = 11.84 YY528 pKa = 9.97 VEE530 pKa = 4.88 GCVKK534 pKa = 10.41 PSPLSAYY541 pKa = 10.22 SEE543 pKa = 4.28 NVEE546 pKa = 3.94 MADD549 pKa = 3.37 NYY551 pKa = 11.04 FLVSSLGSNPKK562 pKa = 10.53 AKK564 pKa = 10.74 GGDD567 pKa = 3.68 DD568 pKa = 3.75 FVLLIGPNTEE578 pKa = 4.64 FVCPCYY584 pKa = 10.77 YY585 pKa = 10.68 LYY587 pKa = 10.62 QSSVYY592 pKa = 9.97 RR593 pKa = 11.84 YY594 pKa = 10.02 DD595 pKa = 3.02 VGKK598 pKa = 10.31 YY599 pKa = 8.14 VSSVKK604 pKa = 10.49 VGSRR608 pKa = 11.84 TKK610 pKa = 10.5 QLNTTSGYY618 pKa = 6.42 WQEE621 pKa = 3.67 YY622 pKa = 5.88 MLRR625 pKa = 11.84 GKK627 pKa = 8.62 SVKK630 pKa = 9.68 YY631 pKa = 9.69 QATLGHH637 pKa = 6.08 VLYY640 pKa = 10.76 ANKK643 pKa = 9.43 PWWYY647 pKa = 8.53 TFMVLAISLLIIGPFSIVYY666 pKa = 9.73 AKK668 pKa = 10.2 RR669 pKa = 11.84 VSCLSHH675 pKa = 6.62 HH676 pKa = 6.83 FSGIHH681 pKa = 4.65 SQQVPVLASDD691 pKa = 4.7 LVSTPPSRR699 pKa = 11.84 GLTHH703 pKa = 7.17 GLVAKK708 pKa = 10.39 QKK710 pKa = 10.47 GSNIVIDD717 pKa = 4.37 PDD719 pKa = 3.73 SGTGTDD725 pKa = 4.43 LSAEE729 pKa = 4.26 EE730 pKa = 4.94 KK731 pKa = 10.7 FGLDD735 pKa = 5.05 KK736 pKa = 10.76 EE737 pKa = 4.37 RR738 pKa = 11.84 CRR740 pKa = 11.84 CNPGCKK746 pKa = 9.45 CSVGGHH752 pKa = 5.73 SPSCDD757 pKa = 3.17 LATLSIQQCKK767 pKa = 10.01 KK768 pKa = 9.25 YY769 pKa = 10.2 RR770 pKa = 11.84 SSGYY774 pKa = 9.65 CSHH777 pKa = 6.93 AFYY780 pKa = 10.87 GVAYY784 pKa = 9.54 FLFYY788 pKa = 10.88 FFLFALISGCVVVSAQPALTYY809 pKa = 9.36 TVNEE813 pKa = 3.99 EE814 pKa = 3.69 PRR816 pKa = 11.84 YY817 pKa = 10.52 DD818 pKa = 3.56 RR819 pKa = 11.84 AGPEE823 pKa = 4.25 CEE825 pKa = 4.27 VKK827 pKa = 10.77 GSEE830 pKa = 4.35 TVFNALKK837 pKa = 10.13 DD838 pKa = 3.69 SCNAWPYY845 pKa = 9.99 EE846 pKa = 4.0 IKK848 pKa = 10.61 ACPNLFQFVKK858 pKa = 10.02 PGAPGAEE865 pKa = 4.09 SNFYY869 pKa = 10.4 KK870 pKa = 10.81 VPFYY874 pKa = 10.72 EE875 pKa = 4.49 GSRR878 pKa = 11.84 DD879 pKa = 3.41 FRR881 pKa = 11.84 EE882 pKa = 4.26 RR883 pKa = 11.84 KK884 pKa = 9.94 HH885 pKa = 6.27 EE886 pKa = 4.42 DD887 pKa = 2.95 KK888 pKa = 11.22 QNFMMRR894 pKa = 11.84 NLSLCEE900 pKa = 3.89 VVDD903 pKa = 4.05 LGGNNTCEE911 pKa = 3.98 SAGYY915 pKa = 9.94 SDD917 pKa = 4.96 EE918 pKa = 4.18 EE919 pKa = 4.11 LAEE922 pKa = 4.35 VFASPDD928 pKa = 3.38 TVGSVFQSMEE938 pKa = 4.28 TKK940 pKa = 10.69 CEE942 pKa = 4.21 GEE944 pKa = 3.9 NCTCGFFTKK953 pKa = 10.33 DD954 pKa = 2.99 IKK956 pKa = 10.81 ISLAQRR962 pKa = 11.84 SSTTYY967 pKa = 10.65 SFSCGSTSMSFKK979 pKa = 10.87 VVTGDD984 pKa = 3.59 LQYY987 pKa = 11.13 HH988 pKa = 5.26 EE989 pKa = 4.74 NFRR992 pKa = 11.84 YY993 pKa = 10.07 DD994 pKa = 3.41 YY995 pKa = 10.03 STAEE999 pKa = 3.71 YY1000 pKa = 10.89 RR1001 pKa = 11.84 EE1002 pKa = 4.12 FTEE1005 pKa = 5.44 LRR1007 pKa = 11.84 AQRR1010 pKa = 11.84 FLAPVTCRR1018 pKa = 11.84 CDD1020 pKa = 3.59 VDD1022 pKa = 4.22 PQTCDD1027 pKa = 3.2 DD1028 pKa = 3.75 QGGSRR1033 pKa = 11.84 SANASSVDD1041 pKa = 3.19 QKK1043 pKa = 11.44 LFYY1046 pKa = 10.29 FGHH1049 pKa = 6.35 YY1050 pKa = 10.42 DD1051 pKa = 3.37 IMPEE1055 pKa = 3.89 PKK1057 pKa = 9.98 QYY1059 pKa = 10.56 TRR1061 pKa = 11.84 VCKK1064 pKa = 10.18 QDD1066 pKa = 2.56 TCYY1069 pKa = 11.54 ALMQAPIVNMSRR1081 pKa = 11.84 TADD1084 pKa = 3.5 VFTSSPTSPFLPICFVKK1101 pKa = 9.75 DD1102 pKa = 3.63 TKK1104 pKa = 10.77 VKK1106 pKa = 10.29 CYY1108 pKa = 11.01 VLITFLQVDD1117 pKa = 4.61 LSDD1120 pKa = 3.89 LLGINEE1126 pKa = 4.45 FSLTFSLSGVRR1137 pKa = 11.84 YY1138 pKa = 8.19 STAEE1142 pKa = 3.99 TVAVTVEE1149 pKa = 4.16 PVPGAIDD1156 pKa = 3.46 SVVTIRR1162 pKa = 11.84 KK1163 pKa = 9.28 VGIPPSSPLGAVGDD1177 pKa = 3.91 LRR1179 pKa = 11.84 YY1180 pKa = 9.78 FGYY1183 pKa = 10.39 SVLAGIGASNISTPDD1198 pKa = 3.43 DD1199 pKa = 3.58 LLMVKK1204 pKa = 10.32 GCGYY1208 pKa = 11.13 GGFTGGRR1215 pKa = 11.84 MEE1217 pKa = 5.15 FPYY1220 pKa = 10.63 KK1221 pKa = 10.4 SAGTFYY1227 pKa = 10.75 PRR1229 pKa = 11.84 LLTLNTPPTIFQIQCPSAKK1248 pKa = 9.39 VDD1250 pKa = 3.58 SVPRR1254 pKa = 11.84 EE1255 pKa = 3.77 WAAVRR1260 pKa = 11.84 PEE1262 pKa = 3.35 WRR1264 pKa = 11.84 TKK1266 pKa = 10.58 FEE1268 pKa = 4.71 HH1269 pKa = 6.42 KK1270 pKa = 10.19 PVWEE1274 pKa = 3.92 NQILYY1279 pKa = 10.37 DD1280 pKa = 3.92 WIKK1283 pKa = 10.39 QFRR1286 pKa = 11.84 NYY1288 pKa = 9.26 TRR1290 pKa = 11.84 FEE1292 pKa = 4.06 EE1293 pKa = 4.66 SDD1295 pKa = 3.35 GLTYY1299 pKa = 10.22 FAFGIKK1305 pKa = 9.45 PVPQVVDD1312 pKa = 3.13 STKK1315 pKa = 9.64 IVRR1318 pKa = 11.84 SFSVVYY1324 pKa = 10.93 GEE1326 pKa = 4.65 GFPLNDD1332 pKa = 3.09 YY1333 pKa = 9.3 AQQVRR1338 pKa = 11.84 VRR1340 pKa = 11.84 LAQALACVAEE1350 pKa = 4.53 GVGVSVDD1357 pKa = 3.76 QVEE1360 pKa = 4.11 MDD1362 pKa = 3.1 ATSFFTRR1369 pKa = 11.84 VGRR1372 pKa = 11.84 AHH1374 pKa = 6.52 IQYY1377 pKa = 10.32 KK1378 pKa = 9.97 IYY1380 pKa = 11.09 VPMAYY1385 pKa = 10.05 VPIKK1389 pKa = 10.63 RR1390 pKa = 11.84 EE1391 pKa = 3.87 VVAQAVDD1398 pKa = 3.34 SCEE1401 pKa = 4.23 SKK1403 pKa = 10.61 FVSIVIQGKK1412 pKa = 9.94 SYY1414 pKa = 9.25 TAVQYY1419 pKa = 11.34 DD1420 pKa = 3.48 KK1421 pKa = 11.18 AALIGTFYY1429 pKa = 11.46 GLGRR1433 pKa = 11.84 FGANTNLPYY1442 pKa = 10.98 LNTIRR1447 pKa = 11.84 KK1448 pKa = 5.5 TASPLAVMSMHH1459 pKa = 7.46 LDD1461 pKa = 3.25 TTFPFIQDD1469 pKa = 3.4 PPEE1472 pKa = 4.09 VVDD1475 pKa = 6.04 FVVDD1479 pKa = 3.26 KK1480 pKa = 11.39 CDD1482 pKa = 3.39 GFSIAVACSFCVALNQTSTPGSYY1505 pKa = 10.39 VINLLCPRR1513 pKa = 11.84 HH1514 pKa = 5.95 KK1515 pKa = 10.5 CFSSLVVTSIDD1526 pKa = 3.48 CGVVNIVGTEE1536 pKa = 3.9 DD1537 pKa = 3.19 EE1538 pKa = 4.32 VRR1540 pKa = 11.84 NTNFSISFKK1549 pKa = 11.34 NEE1551 pKa = 3.45 FLMSAQPLKK1560 pKa = 10.98 VDD1562 pKa = 3.4 IEE1564 pKa = 4.3 LAQTLADD1571 pKa = 3.58 QNKK1574 pKa = 9.96 NNDD1577 pKa = 3.79 LLLGGEE1583 pKa = 4.08 PTIPRR1588 pKa = 11.84 LRR1590 pKa = 11.84 SVTQPVNPGSNSSVGIYY1607 pKa = 9.78 VAIAVLFACFFGVIGGACWLQSQRR1631 pKa = 11.84 EE1632 pKa = 4.21 DD1633 pKa = 3.26 VTQEE1637 pKa = 4.78 KK1638 pKa = 10.62 EE1639 pKa = 4.05 DD1640 pKa = 4.07 LDD1642 pKa = 4.15 EE1643 pKa = 5.91 KK1644 pKa = 11.07 EE1645 pKa = 4.53 SLLKK1649 pKa = 10.31 RR1650 pKa = 11.84 VPSKK1654 pKa = 11.02 YY1655 pKa = 9.36 LTFVKK1660 pKa = 10.11 SRR1662 pKa = 11.84 KK1663 pKa = 9.35 PFVPTLAFKK1672 pKa = 9.85 STSNVGRR1679 pKa = 11.84 LTLFLFLVSTTVVFGCFSDD1698 pKa = 3.82 SQPPRR1703 pKa = 11.84 LLSFDD1708 pKa = 3.33 VDD1710 pKa = 3.89 TCVGNALLLDD1720 pKa = 4.33 CNFSIALADD1729 pKa = 3.82 NLSSPTTFHH1738 pKa = 7.49 IVQQDD1743 pKa = 2.76 SDD1745 pKa = 3.74 FAHH1748 pKa = 6.79 AVTLFSNVSGVFRR1761 pKa = 11.84 FPSPPFYY1768 pKa = 10.49 FQSLPFRR1775 pKa = 11.84 LMWTGRR1781 pKa = 11.84 VLSSVLPRR1789 pKa = 11.84 NSSFSMLADD1798 pKa = 3.48 VEE1800 pKa = 4.73 RR1801 pKa = 11.84 MVTLQQRR1808 pKa = 11.84 TDD1810 pKa = 3.2 LKK1812 pKa = 11.12 GFYY1815 pKa = 10.53 CFLTYY1820 pKa = 11.02 AHH1822 pKa = 7.41 DD1823 pKa = 4.59 SDD1825 pKa = 5.27 LVWEE1829 pKa = 4.39 ATFNVNGASIKK1840 pKa = 9.83 RR1841 pKa = 11.84 TVARR1845 pKa = 11.84 CEE1847 pKa = 3.76 KK1848 pKa = 10.81 VEE1850 pKa = 4.11 TFKK1853 pKa = 11.47 VGVFTNVKK1861 pKa = 10.02 KK1862 pKa = 10.59 EE1863 pKa = 4.13 PKK1865 pKa = 9.96 CVITQAPNHH1874 pKa = 6.05 FSFAIEE1880 pKa = 4.38 HH1881 pKa = 5.98 EE1882 pKa = 4.5 TDD1884 pKa = 2.78 QSAVVKK1890 pKa = 10.02 LIVVPDD1896 pKa = 3.53 EE1897 pKa = 4.5 RR1898 pKa = 11.84 IQRR1901 pKa = 11.84 LSCTQLGAGEE1911 pKa = 4.58 DD1912 pKa = 4.2 GNRR1915 pKa = 11.84 AWDD1918 pKa = 3.44 VRR1920 pKa = 11.84 EE1921 pKa = 4.14 LFKK1924 pKa = 11.36 APTTTSAPATTTTVLVVPEE1943 pKa = 4.08 TTTLKK1948 pKa = 10.99 KK1949 pKa = 9.79 LTTSTRR1955 pKa = 11.84 VSIPVEE1961 pKa = 4.05 TSPKK1965 pKa = 10.26 RR1966 pKa = 11.84 SDD1968 pKa = 3.46 PTPGIPATTEE1978 pKa = 3.39 KK1979 pKa = 10.72 SAATIQDD1986 pKa = 3.97 SPSMEE1991 pKa = 3.8 ITLSPIVTTLAPTTEE2006 pKa = 4.31 APSVTVKK2013 pKa = 10.83 NVFLNTTRR2021 pKa = 11.84 PFAGSSDD2028 pKa = 3.36 ASTLGVGSVGGVSQLVDD2045 pKa = 3.77 EE2046 pKa = 4.79 VTTAAGSVKK2055 pKa = 10.66 SGDD2058 pKa = 3.79 SSSDD2062 pKa = 3.27 TSSSKK2067 pKa = 10.66 PNNGSPLQLKK2077 pKa = 9.27 PEE2079 pKa = 4.08 PVRR2082 pKa = 11.84 RR2083 pKa = 11.84 LPQPSALRR2091 pKa = 11.84 LEE2093 pKa = 4.9 DD2094 pKa = 3.82 GLRR2097 pKa = 11.84 KK2098 pKa = 9.5 PSSDD2102 pKa = 3.32 VPTARR2107 pKa = 11.84 DD2108 pKa = 5.32 DD2109 pKa = 3.81 LTDD2112 pKa = 3.28 WNSGHH2117 pKa = 6.32 RR2118 pKa = 11.84 TDD2120 pKa = 4.08 KK2121 pKa = 11.03 KK2122 pKa = 10.51 EE2123 pKa = 3.73 RR2124 pKa = 11.84 GKK2126 pKa = 10.65 RR2127 pKa = 11.84 WDD2129 pKa = 3.54 LLQWGMVAVCIVLVVILAAVFVYY2152 pKa = 9.32 TLYY2155 pKa = 10.97 VGCCKK2160 pKa = 9.5 IDD2162 pKa = 3.46 RR2163 pKa = 11.84 SDD2165 pKa = 3.37 RR2166 pKa = 11.84 TYY2168 pKa = 11.12 KK2169 pKa = 10.51 PPSRR2173 pKa = 11.84 SQDD2176 pKa = 2.97 RR2177 pKa = 11.84 KK2178 pKa = 8.52 PLIRR2182 pKa = 11.84 GSVSSRR2188 pKa = 11.84 PNVSVYY2194 pKa = 10.39 IVVFCLLSPMCLGMMSRR2211 pKa = 11.84 LAVFQSLLRR2220 pKa = 11.84 QDD2222 pKa = 4.0 CAFSLVGTSRR2232 pKa = 11.84 NMCGMGKK2239 pKa = 9.15 QVLPIVVPAVSPYY2252 pKa = 11.29 ADD2254 pKa = 3.79 GSPVKK2259 pKa = 9.56 ATASACSGMTCTCSISTSVTSRR2281 pKa = 11.84 QLGVPFTFVSKK2292 pKa = 10.58 CDD2294 pKa = 3.43 EE2295 pKa = 4.43 FPTVFEE2301 pKa = 4.26 VVPVSSRR2308 pKa = 11.84 VVYY2311 pKa = 10.45 SYY2313 pKa = 10.93 VFPPEE2318 pKa = 3.38 VDD2320 pKa = 3.31 LRR2322 pKa = 11.84 LATGEE2327 pKa = 4.31 KK2328 pKa = 10.43 LVDD2331 pKa = 3.94 SEE2333 pKa = 4.81 PCAPCPDD2340 pKa = 3.0 GRR2342 pKa = 11.84 GVYY2345 pKa = 10.1 RR2346 pKa = 11.84 GTITKK2351 pKa = 9.24 CQRR2354 pKa = 11.84 LCGVKK2359 pKa = 10.22 HH2360 pKa = 6.33 SSTNSTRR2367 pKa = 11.84 YY2368 pKa = 7.45 TVVEE2372 pKa = 3.89 ATLVYY2377 pKa = 9.94 SFCVLGNGKK2386 pKa = 8.99 VNCFEE2391 pKa = 4.34 RR2392 pKa = 11.84 AVQIPHH2398 pKa = 7.59 PDD2400 pKa = 3.56 HH2401 pKa = 7.74 IGIAYY2406 pKa = 9.45 HH2407 pKa = 6.58 GGMPVAYY2414 pKa = 9.86 DD2415 pKa = 4.56 LDD2417 pKa = 3.8 PQFIEE2422 pKa = 5.71 DD2423 pKa = 4.02 YY2424 pKa = 11.3 DD2425 pKa = 5.04 SIDD2428 pKa = 3.15 KK2429 pKa = 10.48 VRR2431 pKa = 11.84 YY2432 pKa = 8.82 SLPNFGSKK2440 pKa = 10.66 GDD2442 pKa = 3.68 IAVSGHH2448 pKa = 5.65 QIAVEE2453 pKa = 4.02 DD2454 pKa = 4.01 VAVKK2458 pKa = 9.95 TEE2460 pKa = 3.61 VRR2462 pKa = 11.84 IPISLTYY2469 pKa = 11.31 VMYY2472 pKa = 10.66 SPQKK2476 pKa = 10.91 NRR2478 pKa = 11.84 MLSLRR2483 pKa = 11.84 LAGCHH2488 pKa = 6.06 LRR2490 pKa = 11.84 QTAYY2494 pKa = 10.41 GQILASCSLLVSPSTKK2510 pKa = 9.56 ISNPLTLYY2518 pKa = 10.75 LSVSEE2523 pKa = 5.32 GYY2525 pKa = 9.58 FVPAPSITLIPGLRR2539 pKa = 11.84 AYY2541 pKa = 10.32 NLPFDD2546 pKa = 4.35 VKK2548 pKa = 10.86 VATTTRR2554 pKa = 11.84 GEE2556 pKa = 4.16 IIARR2560 pKa = 11.84 TYY2562 pKa = 10.04 HH2563 pKa = 6.38 GPRR2566 pKa = 11.84 IYY2568 pKa = 10.64 LKK2570 pKa = 10.56 YY2571 pKa = 10.44 VFTHH2575 pKa = 6.29 FEE2577 pKa = 3.9 YY2578 pKa = 10.83 DD2579 pKa = 3.3 GLFFNTYY2586 pKa = 9.34 SKK2588 pKa = 10.81 PLITDD2593 pKa = 3.28 VTKK2596 pKa = 11.04 VSLPPVFFGMIGVMIAMIVLHH2617 pKa = 6.44 LSVIACNYY2625 pKa = 8.25 VRR2627 pKa = 11.84 ARR2629 pKa = 11.84 YY2630 pKa = 9.22 LRR2632 pKa = 11.84 TLHH2635 pKa = 6.38 NCIAPKK2641 pKa = 10.37 RR2642 pKa = 11.84 GATSQNLTDD2651 pKa = 5.39 FGRR2654 pKa = 11.84 EE2655 pKa = 4.03 SNVVLFKK2662 pKa = 10.77 SASSVDD2668 pKa = 3.45 VLQWFVLIACIAGLGIGAYY2687 pKa = 9.59 FLYY2690 pKa = 10.94 YY2691 pKa = 10.77 LLQSALSVVDD2701 pKa = 4.13 SVVSPINDD2709 pKa = 2.88 VSNALFGWLSAGAAGCFDD2727 pKa = 3.34 THH2729 pKa = 7.2 FGVMCEE2735 pKa = 3.98 DD2736 pKa = 3.15 VLYY2739 pKa = 10.75 AGRR2742 pKa = 11.84 YY2743 pKa = 7.62 RR2744 pKa = 11.84 KK2745 pKa = 9.93 LLTTEE2750 pKa = 3.93 ACVAEE2755 pKa = 5.04 CRR2757 pKa = 11.84 RR2758 pKa = 11.84 QPGCTHH2764 pKa = 5.98 VSMSTVGCVLSSGEE2778 pKa = 4.63 LMTKK2782 pKa = 8.19 VTGVVSTKK2790 pKa = 10.22 LAPLVAGVVDD2800 pKa = 4.81 GASATNGCVSFFLSTGVVIVCFIINLFFYY2829 pKa = 10.97 VRR2831 pKa = 11.84 GGLSSGRR2838 pKa = 11.84 GIGRR2842 pKa = 11.84 GRR2844 pKa = 11.84 YY2845 pKa = 9.0 AGYY2848 pKa = 10.96 GFIPSPFSVPNFMYY2862 pKa = 10.29 SGPPRR2867 pKa = 11.84 QRR2869 pKa = 11.84 RR2870 pKa = 11.84 QGQKK2874 pKa = 9.57 KK2875 pKa = 7.58 ATPVVPTASKK2885 pKa = 11.02 ASAATPAAGQKK2896 pKa = 9.99 DD2897 pKa = 3.69 AATEE2901 pKa = 3.85 KK2902 pKa = 10.93 ARR2904 pKa = 11.84 TSKK2907 pKa = 10.84 NGNKK2911 pKa = 9.3 VVTLGVNNRR2920 pKa = 11.84 SSGVKK2925 pKa = 9.89 AYY2927 pKa = 10.24 AAAALNNMSEE2937 pKa = 4.26 SQLTKK2942 pKa = 11.04 AMYY2945 pKa = 10.12 AVQTTPGRR2953 pKa = 11.84 APNRR2957 pKa = 11.84 PGVLIQMYY2965 pKa = 10.28 VSDD2968 pKa = 4.44 PPAVRR2973 pKa = 11.84 MEE2975 pKa = 4.01 GLEE2978 pKa = 4.26 SNVRR2982 pKa = 11.84 VLDD2985 pKa = 3.54 PTRR2988 pKa = 11.84 ISEE2991 pKa = 4.01 MGAGINVRR2999 pKa = 11.84 DD3000 pKa = 4.0 NMSVVIKK3007 pKa = 10.2 QNYY3010 pKa = 7.61 EE3011 pKa = 3.65 GHH3013 pKa = 6.18 PWEE3016 pKa = 4.49 VSSKK3020 pKa = 8.03 EE3021 pKa = 4.23 TMVSNRR3027 pKa = 11.84 DD3028 pKa = 3.47 TVVEE3032 pKa = 4.07 VSDD3035 pKa = 4.06 PKK3037 pKa = 10.82 GTIPRR3042 pKa = 11.84 NRR3044 pKa = 11.84 KK3045 pKa = 8.5 IALAQNLRR3053 pKa = 11.84 TLITTLSSKK3062 pKa = 10.23 SANSMVAAYY3071 pKa = 9.06 EE3072 pKa = 4.26 YY3073 pKa = 11.39 YY3074 pKa = 10.66 SINQSDD3080 pKa = 4.18 LLKK3083 pKa = 10.56 FAFTVLHH3090 pKa = 6.3 EE3091 pKa = 4.75 SSFFSPSHH3099 pKa = 6.31 FSPMDD3104 pKa = 3.09 AHH3106 pKa = 7.15 DD3107 pKa = 4.83 KK3108 pKa = 10.45 IKK3110 pKa = 11.09 SRR3112 pKa = 11.84 FDD3114 pKa = 3.82 KK3115 pKa = 10.8 IQEE3118 pKa = 4.37 AKK3120 pKa = 9.85 PMHH3123 pKa = 6.87 PIVSIILAVSTEE3135 pKa = 4.05 KK3136 pKa = 10.98 PEE3138 pKa = 4.31 FPLPLTDD3145 pKa = 3.56 AQKK3148 pKa = 11.01 NALAVFDD3155 pKa = 3.97 QLSMYY3160 pKa = 7.61 EE3161 pKa = 4.3 AKK3163 pKa = 9.72 WDD3165 pKa = 3.52 EE3166 pKa = 4.85 DD3167 pKa = 3.64 GFPRR3171 pKa = 11.84 NGSSEE3176 pKa = 4.43 EE3177 pKa = 4.32 EE3178 pKa = 4.1 IAPMPDD3184 pKa = 3.33 EE3185 pKa = 4.93 EE3186 pKa = 4.78 FMADD3190 pKa = 3.7 VEE3192 pKa = 4.44 CSPEE3196 pKa = 4.03 IVSFLHH3202 pKa = 7.53 DD3203 pKa = 4.31 AFTEE3207 pKa = 4.27 KK3208 pKa = 10.56 NVEE3211 pKa = 4.1 LEE3213 pKa = 4.27 PEE3215 pKa = 4.15 LEE3217 pKa = 4.19 EE3218 pKa = 5.05 ASEE3221 pKa = 4.1 II3222 pKa = 4.29
Molecular weight: 352.01 kDa
Isoelectric point according different methods:
IPC2.protein.svr19 5.819
IPC2_protein 6.008
IPC_protein 6.033
Toseland 6.148
ProMoST 6.44
Dawson 6.364
Bjellqvist 6.402
Wikipedia 6.364
Rodwell 6.351
Grimsley 6.198
Solomon 6.364
Lehninger 6.364
Nozaki 6.678
DTASelect 6.795
Thurlkill 6.81
EMBOSS 6.781
Sillero 6.751
Patrickios 3.63
IPC_peptide 6.376
IPC2_peptide 6.649
IPC2.peptide.svr19 6.642
Peptides (in silico digests for buttom-up proteomics)
Below you can find
in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.
Try ESI
ChTry ESI
ArgC ESI
LysN ESI
TryLysC ESI
Try MALDI
ChTry MALDI
ArgC MALDI
LysN MALDI
TryLysC MALDI
Try LTQ
ChTry LTQ
ArgC LTQ
LysN LTQ
TryLysC LTQ
Try MSlow
ChTry MSlow
ArgC MSlow
LysN MSlow
TryLysC MSlow
Try MShigh
ChTry MShigh
ArgC MShigh
LysN MShigh
TryLysC MShigh
General Statistics
Number of major isoforms
Number of additional isoforms
Number of all proteins
Number of amino acids
Min. Seq. Length
Max. Seq. Length
Avg. Seq. Length
Avg. Mol. Weight
3
0
3
17415
3222
8376
5805.0
643.89
Amino acid frequency
Ala
Cys
Asp
Glu
Phe
Gly
His
Ile
Lys
Leu
6.816 ± 0.093
2.595 ± 0.174
5.639 ± 0.208
5.834 ± 0.331
6.115 ± 0.224
6.747 ± 0.105
2.199 ± 0.201
4.318 ± 0.122
4.892 ± 0.159
9.113 ± 0.288
Met
Asn
Gln
Pro
Arg
Ser
Thr
Val
Trp
Tyr
1.728 ± 0.059
4.048 ± 0.204
4.203 ± 0.413
2.664 ± 0.1
4.933 ± 0.061
8.125 ± 0.477
5.668 ± 0.299
10.095 ± 0.161
0.81 ± 0.045
3.451 ± 0.111
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level
Most of the basic statistics you can see at this page can be downloaded from this CSV file
For dipeptide frequency statistics click here