Grapevine endophyte alphaendornavirus
Average proteome isoelectric point is 6.05
Get precalculated fractions of proteins
Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
All
Note: above files contain also dissociation constants (pKa)
Virtual 2D-PAGE plot for 1 proteins (isoelectric point calculated using IPC2_protein)
Get csv file with sequences according to given criteria:
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Summary statistics related to proteome-wise predictions
Protein with the lowest isoelectric point:
>tr|K7RTN4|K7RTN4_9VIRU Polyprotein OS=Grapevine endophyte alphaendornavirus OX=1249676 PE=4 SV=1
MM1 pKa = 7.09 TPRR4 pKa = 11.84 RR5 pKa = 11.84 SRR7 pKa = 11.84 KK8 pKa = 7.3 YY9 pKa = 10.22 CKK11 pKa = 9.1 RR12 pKa = 11.84 TKK14 pKa = 8.9 ITHH17 pKa = 5.99 SGHH20 pKa = 5.47 YY21 pKa = 9.31 PKK23 pKa = 10.88 GSARR27 pKa = 11.84 NEE29 pKa = 3.49 IKK31 pKa = 10.61 LRR33 pKa = 11.84 SLHH36 pKa = 6.27 IYY38 pKa = 10.0 QYY40 pKa = 10.85 GIEE43 pKa = 4.44 GDD45 pKa = 3.43 HH46 pKa = 7.55 DD47 pKa = 3.83 IPKK50 pKa = 9.08 LTIHH54 pKa = 6.25 HH55 pKa = 5.77 TLKK58 pKa = 11.01 GEE60 pKa = 3.84 HH61 pKa = 5.94 QYY63 pKa = 11.03 IDD65 pKa = 3.9 TYY67 pKa = 11.42 LADD70 pKa = 3.73 QNDD73 pKa = 4.35 VINTRR78 pKa = 11.84 RR79 pKa = 11.84 LGISGVIDD87 pKa = 3.24 IFHH90 pKa = 5.93 QRR92 pKa = 11.84 KK93 pKa = 8.95 EE94 pKa = 4.16 YY95 pKa = 10.26 PVDD98 pKa = 3.37 HH99 pKa = 7.39 PYY101 pKa = 11.33 DD102 pKa = 3.61 EE103 pKa = 4.75 LTFNGNTSHH112 pKa = 6.71 VRR114 pKa = 11.84 DD115 pKa = 3.68 GLYY118 pKa = 10.93 YY119 pKa = 9.39 IDD121 pKa = 5.83 DD122 pKa = 3.63 YY123 pKa = 11.53 HH124 pKa = 9.51 GEE126 pKa = 4.03 IKK128 pKa = 9.09 PTYY131 pKa = 10.16 NFNTYY136 pKa = 9.49 RR137 pKa = 11.84 AALMDD142 pKa = 5.95 DD143 pKa = 4.04 IYY145 pKa = 11.31 KK146 pKa = 10.5 SNHH149 pKa = 3.36 VHH151 pKa = 4.82 GTKK154 pKa = 10.22 RR155 pKa = 11.84 MHH157 pKa = 6.64 TLVNWLTDD165 pKa = 3.28 KK166 pKa = 11.14 SVAFPYY172 pKa = 11.15 GNMAQKK178 pKa = 10.56 RR179 pKa = 11.84 YY180 pKa = 10.16 GYY182 pKa = 10.88 LEE184 pKa = 4.53 ALDD187 pKa = 4.72 GYY189 pKa = 9.42 YY190 pKa = 9.75 IKK192 pKa = 10.58 CAHH195 pKa = 6.95 CDD197 pKa = 3.39 CLTYY201 pKa = 10.94 LPLSTLLPPTITRR214 pKa = 11.84 AQLTQFLRR222 pKa = 11.84 EE223 pKa = 3.73 FRR225 pKa = 11.84 DD226 pKa = 3.31 QRR228 pKa = 11.84 EE229 pKa = 4.55 CYY231 pKa = 9.65 MPDD234 pKa = 3.31 PEE236 pKa = 5.02 IFGDD240 pKa = 3.67 MAMMVPMCFSTSNGNCFNCDD260 pKa = 2.69 EE261 pKa = 4.86 DD262 pKa = 6.0 LFTEE266 pKa = 4.62 TVKK269 pKa = 10.1 MAYY272 pKa = 9.86 AIYY275 pKa = 9.82 SEE277 pKa = 4.21 SFAYY281 pKa = 10.58 HH282 pKa = 4.93 NVIRR286 pKa = 11.84 GTQIEE291 pKa = 5.05 EE292 pKa = 3.92 MTKK295 pKa = 10.02 MNMLQGAPPDD305 pKa = 4.34 DD306 pKa = 3.92 MPAALSKK313 pKa = 11.17 YY314 pKa = 9.43 NEE316 pKa = 3.91 LHH318 pKa = 5.92 NRR320 pKa = 11.84 HH321 pKa = 5.89 AAKK324 pKa = 10.53 ALAKK328 pKa = 10.18 MNINHH333 pKa = 7.18 LNTIYY338 pKa = 10.39 TINDD342 pKa = 3.24 MTRR345 pKa = 11.84 TEE347 pKa = 4.02 MMSTRR352 pKa = 11.84 SHH354 pKa = 5.83 LHH356 pKa = 4.55 ITSTARR362 pKa = 11.84 INTTPMTSLEE372 pKa = 4.17 SEE374 pKa = 4.6 EE375 pKa = 4.09 ILLIGDD381 pKa = 4.52 LASATVGNLVHH392 pKa = 6.79 HH393 pKa = 7.22 PSTLVVNASLLHH405 pKa = 6.2 ICDD408 pKa = 4.67 TICNGPYY415 pKa = 10.14 FADD418 pKa = 3.18 TGITVNVPMSVEE430 pKa = 4.07 NYY432 pKa = 10.53 LEE434 pKa = 4.38 VIPAQHH440 pKa = 6.63 SFDD443 pKa = 5.15 KK444 pKa = 10.79 LINWAIDD451 pKa = 3.24 GAYY454 pKa = 9.83 IMLLRR459 pKa = 11.84 PDD461 pKa = 3.31 VSDD464 pKa = 5.13 IIVKK468 pKa = 10.02 QDD470 pKa = 2.51 ASYY473 pKa = 11.06 YY474 pKa = 7.88 YY475 pKa = 10.22 TIATGTDD482 pKa = 3.51 VLVKK486 pKa = 9.9 WDD488 pKa = 3.59 VHH490 pKa = 5.6 AHH492 pKa = 6.06 ALLANSAKK500 pKa = 10.54 YY501 pKa = 10.32 FDD503 pKa = 3.69 GANYY507 pKa = 10.14 FNIQTITHH515 pKa = 6.89 GSHH518 pKa = 5.48 LQIVKK523 pKa = 10.07 LVPADD528 pKa = 3.97 NTWHH532 pKa = 6.92 ARR534 pKa = 11.84 TLGNKK539 pKa = 7.44 PTFEE543 pKa = 3.97 ALIPVFDD550 pKa = 5.79 PINPLATLGVFGTKK564 pKa = 7.91 WEE566 pKa = 4.23 YY567 pKa = 9.57 KK568 pKa = 9.27 TINIEE573 pKa = 3.72 LLRR576 pKa = 11.84 RR577 pKa = 11.84 IVTFALTADD586 pKa = 3.93 KK587 pKa = 10.87 SSSAIEE593 pKa = 4.26 AYY595 pKa = 10.02 FAGILSTHH603 pKa = 4.89 YY604 pKa = 9.62 TIGGKK609 pKa = 9.61 VVDD612 pKa = 4.71 LTNTPITEE620 pKa = 4.31 GLPEE624 pKa = 5.55 LIYY627 pKa = 11.41 AMMILTNRR635 pKa = 11.84 KK636 pKa = 8.61 LVTMWSSILHH646 pKa = 6.18 LNNFSSSNGLEE657 pKa = 4.03 TLTKK661 pKa = 10.27 FFLSRR666 pKa = 11.84 LVKK669 pKa = 10.72 VSVQIADD676 pKa = 3.78 KK677 pKa = 10.47 VLPWFSGVLSKK688 pKa = 9.61 PTEE691 pKa = 3.73 FAKK694 pKa = 10.72 RR695 pKa = 11.84 LLSSKK700 pKa = 10.6 HH701 pKa = 6.3 PIDD704 pKa = 3.74 VDD706 pKa = 4.1 SVFAKK711 pKa = 10.6 LLPLLIITKK720 pKa = 10.3 QSDD723 pKa = 3.6 NTEE726 pKa = 4.62 PIAPPLHH733 pKa = 6.32 VLDD736 pKa = 4.57 SAICHH741 pKa = 5.88 HH742 pKa = 6.84 HH743 pKa = 6.78 SSSCNHH749 pKa = 6.39 SIGDD753 pKa = 3.85 VRR755 pKa = 11.84 CVCCGIMNANAVCACCVQHH774 pKa = 5.87 VKK776 pKa = 10.29 CRR778 pKa = 11.84 HH779 pKa = 5.04 SCQHH783 pKa = 6.05 KK784 pKa = 9.12 CTGNLHH790 pKa = 6.13 ACKK793 pKa = 10.38 SCMNNKK799 pKa = 8.95 PCNTKK804 pKa = 10.19 ARR806 pKa = 11.84 CACCNVYY813 pKa = 10.42 GCQPCPACPIMEE825 pKa = 4.63 PMQLHH830 pKa = 6.87 DD831 pKa = 4.2 VQPSSKK837 pKa = 9.44 MSIVTRR843 pKa = 11.84 LANNAMKK850 pKa = 10.68 VPVAHH855 pKa = 5.78 QQPKK859 pKa = 9.09 TITPAVQRR867 pKa = 11.84 PNLGHH872 pKa = 7.17 DD873 pKa = 3.46 ALMNVPKK880 pKa = 10.44 GGAVFKK886 pKa = 10.63 PNEE889 pKa = 3.93 TAHH892 pKa = 7.97 RR893 pKa = 11.84 MMTDD897 pKa = 3.18 YY898 pKa = 11.32 LQITRR903 pKa = 11.84 PEE905 pKa = 4.33 HH906 pKa = 7.05 IFIIDD911 pKa = 3.53 NSDD914 pKa = 3.39 LYY916 pKa = 10.87 IPMLSFTGQYY926 pKa = 9.37 YY927 pKa = 9.6 VPIQLPNPVVSNPIHH942 pKa = 6.31 GEE944 pKa = 3.97 HH945 pKa = 6.12 YY946 pKa = 10.29 CAYY949 pKa = 10.42 ACIAEE954 pKa = 4.04 QSNYY958 pKa = 7.33 TVQMLKK964 pKa = 10.73 NMHH967 pKa = 6.64 GDD969 pKa = 3.28 RR970 pKa = 11.84 HH971 pKa = 7.22 SMDD974 pKa = 3.64 VVEE977 pKa = 5.43 LRR979 pKa = 11.84 HH980 pKa = 5.74 LLKK983 pKa = 10.39 ILSLNCLLILNDD995 pKa = 3.3 THH997 pKa = 9.63 AEE999 pKa = 3.81 ILRR1002 pKa = 11.84 NGPQANNYY1010 pKa = 8.91 ILIGHH1015 pKa = 6.49 GSITDD1020 pKa = 3.99 EE1021 pKa = 4.39 VPHH1024 pKa = 6.0 AHH1026 pKa = 6.6 WFVPHH1031 pKa = 6.62 IPKK1034 pKa = 8.89 FTDD1037 pKa = 3.01 MPTGYY1042 pKa = 10.24 YY1043 pKa = 10.25 GPHH1046 pKa = 6.49 NFGQPFEE1053 pKa = 5.28 DD1054 pKa = 3.49 FTNFNMWNATTTEE1067 pKa = 4.03 MARR1070 pKa = 11.84 IQQRR1074 pKa = 11.84 LKK1076 pKa = 10.43 VLRR1079 pKa = 11.84 SQVRR1083 pKa = 11.84 HH1084 pKa = 5.44 SDD1086 pKa = 3.29 KK1087 pKa = 11.33 LGDD1090 pKa = 3.54 LALPKK1095 pKa = 10.29 VRR1097 pKa = 11.84 LIKK1100 pKa = 10.75 NVFYY1104 pKa = 9.97 LTNGDD1109 pKa = 3.3 EE1110 pKa = 4.26 HH1111 pKa = 6.38 TPRR1114 pKa = 11.84 LGKK1117 pKa = 9.69 IHH1119 pKa = 7.09 LPLPEE1124 pKa = 4.45 FVDD1127 pKa = 3.94 EE1128 pKa = 4.56 EE1129 pKa = 4.81 LVDD1132 pKa = 3.85 ALNGVDD1138 pKa = 3.78 SKK1140 pKa = 11.3 LVKK1143 pKa = 10.12 SLYY1146 pKa = 10.82 ANQTNEE1152 pKa = 3.61 WSQVRR1157 pKa = 11.84 QDD1159 pKa = 4.23 AINMFKK1165 pKa = 10.63 LRR1167 pKa = 11.84 CCDD1170 pKa = 3.14 INQLLVSDD1178 pKa = 4.52 EE1179 pKa = 4.63 ALMSPLQSYY1188 pKa = 7.6 STTVDD1193 pKa = 2.74 SDD1195 pKa = 3.81 EE1196 pKa = 4.71 PFVPVHH1202 pKa = 6.11 LLNRR1206 pKa = 11.84 VKK1208 pKa = 10.63 PLDD1211 pKa = 3.4 IVILKK1216 pKa = 10.42 KK1217 pKa = 9.95 GTQTHH1222 pKa = 5.06 TCVVAGDD1229 pKa = 3.78 ARR1231 pKa = 11.84 QPCVRR1236 pKa = 11.84 NPYY1239 pKa = 10.13 GSGVTLYY1246 pKa = 9.94 ICKK1249 pKa = 9.74 TSLSSLYY1256 pKa = 10.08 RR1257 pKa = 11.84 NLIMCVKK1264 pKa = 10.6 AINNLDD1270 pKa = 3.86 NIRR1273 pKa = 11.84 SVEE1276 pKa = 4.08 FGDD1279 pKa = 4.36 VVDD1282 pKa = 5.71 GVAGSGKK1289 pKa = 7.27 TTLLRR1294 pKa = 11.84 NLTNRR1299 pKa = 11.84 DD1300 pKa = 3.29 KK1301 pKa = 11.1 ATLVCKK1307 pKa = 9.47 TRR1309 pKa = 11.84 SAIEE1313 pKa = 3.8 SHH1315 pKa = 6.49 YY1316 pKa = 11.12 DD1317 pKa = 3.42 SSFHH1321 pKa = 6.45 TLMTMEE1327 pKa = 4.58 AAGMSHH1333 pKa = 6.93 IVTNILVIDD1342 pKa = 4.29 EE1343 pKa = 4.79 ASMITNVEE1351 pKa = 4.14 LLCCLDD1357 pKa = 3.78 NPNMLVHH1364 pKa = 6.29 MMGDD1368 pKa = 3.3 SMQIGVKK1375 pKa = 10.49 DD1376 pKa = 3.54 MSNVLGNRR1384 pKa = 11.84 KK1385 pKa = 9.23 EE1386 pKa = 4.08 NSLLAQLANTKK1397 pKa = 10.09 LYY1399 pKa = 8.27 HH1400 pKa = 6.08 TYY1402 pKa = 10.84 RR1403 pKa = 11.84 FGQPLVDD1410 pKa = 4.3 KK1411 pKa = 9.6 MLKK1414 pKa = 10.01 QFVPNITCEE1423 pKa = 4.36 PNVHH1427 pKa = 6.24 TEE1429 pKa = 4.24 LTQVTASSYY1438 pKa = 11.62 DD1439 pKa = 3.74 EE1440 pKa = 4.56 IVQLTNNYY1448 pKa = 9.36 KK1449 pKa = 9.67 VDD1451 pKa = 3.42 AVYY1454 pKa = 11.39 VFMDD1458 pKa = 3.79 ADD1460 pKa = 4.02 YY1461 pKa = 11.11 VQLLEE1466 pKa = 4.31 ILGDD1470 pKa = 3.91 KK1471 pKa = 10.44 IAVNKK1476 pKa = 9.19 VHH1478 pKa = 7.35 ASQGKK1483 pKa = 8.65 EE1484 pKa = 3.53 FDD1486 pKa = 3.67 NVLVVHH1492 pKa = 6.97 WGNFQVEE1499 pKa = 4.08 TSIVKK1504 pKa = 10.03 SSKK1507 pKa = 10.51 FLFTAATRR1515 pKa = 11.84 ARR1517 pKa = 11.84 KK1518 pKa = 8.92 HH1519 pKa = 6.17 LIWVTPKK1526 pKa = 9.49 TVNINVSKK1534 pKa = 10.79 IMDD1537 pKa = 3.42 IAYY1540 pKa = 9.42 IGSGYY1545 pKa = 10.29 EE1546 pKa = 4.03 SPHH1549 pKa = 7.3 LFDD1552 pKa = 4.95 VNEE1555 pKa = 4.04 CRR1557 pKa = 11.84 LLRR1560 pKa = 11.84 PMTEE1564 pKa = 4.02 LEE1566 pKa = 3.94 MGLIEE1571 pKa = 5.07 TILSNHH1577 pKa = 6.66 PSAIEE1582 pKa = 3.92 ANSKK1586 pKa = 8.52 FTIRR1590 pKa = 11.84 KK1591 pKa = 8.98 SSITVEE1597 pKa = 4.07 AQVKK1601 pKa = 9.64 KK1602 pKa = 9.8 WLTNINISFTVDD1614 pKa = 2.65 RR1615 pKa = 11.84 LGTHH1619 pKa = 6.78 GNNLASRR1626 pKa = 11.84 TAIDD1630 pKa = 4.05 SIKK1633 pKa = 10.99 DD1634 pKa = 3.47 GIRR1637 pKa = 11.84 ANFPAGFAQLEE1648 pKa = 4.35 SRR1650 pKa = 11.84 ISEE1653 pKa = 3.58 IMSYY1657 pKa = 10.82 SEE1659 pKa = 4.08 TSSGITSDD1667 pKa = 3.67 EE1668 pKa = 3.96 EE1669 pKa = 4.01 NAIGTLYY1676 pKa = 10.91 DD1677 pKa = 3.79 ADD1679 pKa = 4.44 AEE1681 pKa = 4.28 PVDD1684 pKa = 4.54 TNTHH1688 pKa = 4.4 TVSYY1692 pKa = 9.84 HH1693 pKa = 6.29 SYY1695 pKa = 10.29 NISIDD1700 pKa = 3.47 EE1701 pKa = 4.44 TEE1703 pKa = 4.46 QFATPPRR1710 pKa = 11.84 PDD1712 pKa = 3.13 TVRR1715 pKa = 11.84 ASDD1718 pKa = 4.07 DD1719 pKa = 3.76 RR1720 pKa = 11.84 PVPMPLSGASPQIFEE1735 pKa = 4.74 AEE1737 pKa = 4.13 SEE1739 pKa = 4.24 RR1740 pKa = 11.84 LRR1742 pKa = 11.84 KK1743 pKa = 9.95 YY1744 pKa = 10.97 LDD1746 pKa = 3.9 DD1747 pKa = 4.41 VEE1749 pKa = 4.29 QQRR1752 pKa = 11.84 LSAAPTISAAALKK1765 pKa = 8.84 NTAQATTLLQEE1776 pKa = 4.45 ALGDD1780 pKa = 3.8 ASIAEE1785 pKa = 4.32 ALPTHH1790 pKa = 6.19 MQPILTDD1797 pKa = 3.28 DD1798 pKa = 4.28 HH1799 pKa = 7.01 NPTDD1803 pKa = 3.88 SAVATVLTKK1812 pKa = 10.47 QLAHH1816 pKa = 6.11 MVRR1819 pKa = 11.84 SLPRR1823 pKa = 11.84 DD1824 pKa = 3.42 TRR1826 pKa = 11.84 GTQPTPVGAVLSTDD1840 pKa = 3.33 LAEE1843 pKa = 5.92 PIQQCLDD1850 pKa = 3.07 TRR1852 pKa = 11.84 AFGILYY1858 pKa = 9.72 KK1859 pKa = 10.78 LQVKK1863 pKa = 9.71 HH1864 pKa = 5.42 MHH1866 pKa = 6.29 LTAQLWSRR1874 pKa = 11.84 MIILADD1880 pKa = 3.13 IVLSYY1885 pKa = 11.08 QCTSTALTWKK1895 pKa = 9.91 HH1896 pKa = 5.42 QGHH1899 pKa = 7.15 LFKK1902 pKa = 11.12 LSIFGGCSLYY1912 pKa = 10.96 CGFKK1916 pKa = 10.59 FEE1918 pKa = 4.82 YY1919 pKa = 10.59 DD1920 pKa = 3.74 DD1921 pKa = 4.05 DD1922 pKa = 4.34 TVLISSAHH1930 pKa = 6.18 ADD1932 pKa = 3.58 DD1933 pKa = 5.03 TRR1935 pKa = 11.84 DD1936 pKa = 3.49 HH1937 pKa = 7.03 LLNTLNTCNRR1947 pKa = 11.84 HH1948 pKa = 4.0 ITGTTEE1954 pKa = 4.05 GIVRR1958 pKa = 11.84 VISFLSDD1965 pKa = 3.03 DD1966 pKa = 4.02 TLFGSVPRR1974 pKa = 11.84 NTCFKK1979 pKa = 10.19 TYY1981 pKa = 9.47 VEE1983 pKa = 4.74 RR1984 pKa = 11.84 LTNICGGVLTDD1995 pKa = 4.67 CSFDD1999 pKa = 3.67 SVGTRR2004 pKa = 11.84 FQTEE2008 pKa = 3.87 NTSRR2012 pKa = 11.84 AISCDD2017 pKa = 3.28 SYY2019 pKa = 11.54 SDD2021 pKa = 3.59 SFIIPTHH2028 pKa = 5.39 QRR2030 pKa = 11.84 VEE2032 pKa = 4.27 HH2033 pKa = 6.14 YY2034 pKa = 10.36 IVTTSDD2040 pKa = 4.21 GIRR2043 pKa = 11.84 LEE2045 pKa = 4.11 PCNVIVHH2052 pKa = 5.88 TAKK2055 pKa = 10.64 QLVQLFSGIRR2065 pKa = 11.84 GTDD2068 pKa = 2.86 ADD2070 pKa = 4.18 FTLSRR2075 pKa = 11.84 ANKK2078 pKa = 8.12 ATLEE2082 pKa = 4.05 KK2083 pKa = 10.66 TMIRR2087 pKa = 11.84 HH2088 pKa = 6.12 LNAEE2092 pKa = 4.32 EE2093 pKa = 4.38 KK2094 pKa = 10.3 FDD2096 pKa = 4.14 RR2097 pKa = 11.84 PVNIPTQLVRR2107 pKa = 11.84 SEE2109 pKa = 3.96 LWQTFMQQVGSNVITPIAIGTTAVSSIHH2137 pKa = 6.23 GAMLMSALMLRR2148 pKa = 11.84 QMFADD2153 pKa = 4.27 EE2154 pKa = 4.96 PIHH2157 pKa = 6.67 YY2158 pKa = 9.82 IGLNAQLFCLNYY2170 pKa = 10.17 VVGDD2174 pKa = 4.43 TISEE2178 pKa = 4.15 IPGDD2182 pKa = 3.53 GAVYY2186 pKa = 9.85 IRR2188 pKa = 11.84 QMMSAKK2194 pKa = 9.93 AAAIAALIEE2203 pKa = 4.46 GEE2205 pKa = 4.17 SDD2207 pKa = 3.09 ADD2209 pKa = 3.62 EE2210 pKa = 4.62 LKK2212 pKa = 10.79 RR2213 pKa = 11.84 LQDD2216 pKa = 3.33 EE2217 pKa = 4.21 LAIVSDD2223 pKa = 3.56 YY2224 pKa = 10.86 RR2225 pKa = 11.84 AIVASPVRR2233 pKa = 11.84 KK2234 pKa = 8.48 LTICHH2239 pKa = 6.22 PKK2241 pKa = 9.83 YY2242 pKa = 10.21 FNRR2245 pKa = 11.84 YY2246 pKa = 6.88 HH2247 pKa = 6.59 SNRR2250 pKa = 11.84 VFTCYY2255 pKa = 10.18 PYY2257 pKa = 8.44 TTDD2260 pKa = 3.55 PTCIVQDD2267 pKa = 3.76 GKK2269 pKa = 11.27 LLEE2272 pKa = 4.31 ASEE2275 pKa = 4.99 DD2276 pKa = 3.6 GGSFEE2281 pKa = 4.79 VSLDD2285 pKa = 3.23 NTVIIGVVGSYY2296 pKa = 10.95 YY2297 pKa = 7.98 MHH2299 pKa = 6.73 KK2300 pKa = 10.04 HH2301 pKa = 4.52 VEE2303 pKa = 4.1 KK2304 pKa = 10.69 LPEE2307 pKa = 3.78 ITLQSSGIANPNYY2320 pKa = 9.85 RR2321 pKa = 11.84 VFASNVPGMEE2331 pKa = 4.14 TVSIPDD2337 pKa = 3.65 TIFRR2341 pKa = 11.84 RR2342 pKa = 11.84 LVARR2346 pKa = 11.84 AFADD2350 pKa = 3.88 ADD2352 pKa = 3.87 TKK2354 pKa = 11.1 LPDD2357 pKa = 3.55 MIAYY2361 pKa = 9.52 SRR2363 pKa = 11.84 SLLNTMTYY2371 pKa = 8.63 TSKK2374 pKa = 10.99 GYY2376 pKa = 9.61 SFKK2379 pKa = 11.5 YY2380 pKa = 9.95 NDD2382 pKa = 3.95 NPLEE2386 pKa = 4.05 LLQFSIVALNFANRR2400 pKa = 11.84 QRR2402 pKa = 11.84 KK2403 pKa = 6.64 VTGFVNSVLGLGVDD2417 pKa = 3.85 TDD2419 pKa = 3.84 KK2420 pKa = 11.45 SSSYY2424 pKa = 11.36 SPIINLLVEE2433 pKa = 4.15 SLKK2436 pKa = 10.4 TIGLNLMQNQFNQPLQILHH2455 pKa = 6.49 EE2456 pKa = 4.16 MLNRR2460 pKa = 11.84 GTMEE2464 pKa = 4.06 TPVISDD2470 pKa = 3.24 IFAVLRR2476 pKa = 11.84 DD2477 pKa = 3.61 ANYY2480 pKa = 10.26 QEE2482 pKa = 5.03 IYY2484 pKa = 10.14 PSIRR2488 pKa = 11.84 LKK2490 pKa = 10.5 YY2491 pKa = 9.14 RR2492 pKa = 11.84 HH2493 pKa = 5.83 SEE2495 pKa = 3.99 RR2496 pKa = 11.84 SNQTVNSDD2504 pKa = 3.01 TAANDD2509 pKa = 3.31 NDD2511 pKa = 4.03 VDD2513 pKa = 4.01 SHH2515 pKa = 6.88 PNTDD2519 pKa = 4.05 AGDD2522 pKa = 3.79 TTDD2525 pKa = 3.35 VQTTPAVAPTPKK2537 pKa = 9.06 PDD2539 pKa = 3.47 KK2540 pKa = 10.95 GKK2542 pKa = 11.18 GPALPDD2548 pKa = 3.25 NSEE2551 pKa = 4.3 YY2552 pKa = 11.11 ASSSQTQQIAKK2563 pKa = 9.5 FFSDD2567 pKa = 3.4 KK2568 pKa = 11.21 VITTWHH2574 pKa = 6.85 DD2575 pKa = 3.04 MHH2577 pKa = 6.68 EE2578 pKa = 4.08 AWNKK2582 pKa = 8.47 YY2583 pKa = 8.15 VKK2585 pKa = 10.67 SNNQYY2590 pKa = 10.27 QPWEE2594 pKa = 4.42 FNTHH2598 pKa = 5.29 VGDD2601 pKa = 4.37 VLLLYY2606 pKa = 10.64 AGSRR2610 pKa = 11.84 GDD2612 pKa = 4.11 AQPLDD2617 pKa = 4.88 AIAEE2621 pKa = 4.28 VAVAGGLSVRR2631 pKa = 11.84 SLIPADD2637 pKa = 3.44 LHH2639 pKa = 6.74 SRR2641 pKa = 11.84 IPGVHH2646 pKa = 6.12 YY2647 pKa = 10.49 IEE2649 pKa = 5.07 YY2650 pKa = 9.71 CDD2652 pKa = 4.95 SYY2654 pKa = 11.88 DD2655 pKa = 3.96 ALTTCGVNGTIPDD2668 pKa = 3.5 ASTFMTHH2675 pKa = 6.68 AMDD2678 pKa = 5.55 VYY2680 pKa = 9.9 RR2681 pKa = 11.84 HH2682 pKa = 5.04 WLKK2685 pKa = 9.8 EE2686 pKa = 3.97 HH2687 pKa = 5.22 MRR2689 pKa = 11.84 HH2690 pKa = 6.34 RR2691 pKa = 11.84 IVIGMFFSSEE2701 pKa = 3.81 ANLVHH2706 pKa = 5.93 GTEE2709 pKa = 4.03 KK2710 pKa = 10.64 NIRR2713 pKa = 11.84 IIPQLDD2719 pKa = 3.85 DD2720 pKa = 3.62 EE2721 pKa = 4.74 WDD2723 pKa = 3.65 GAAKK2727 pKa = 10.08 CNHH2730 pKa = 5.62 GMSSNSIRR2738 pKa = 11.84 KK2739 pKa = 8.36 FFKK2742 pKa = 10.4 LPKK2745 pKa = 9.81 PVITPYY2751 pKa = 9.88 WAVPYY2756 pKa = 10.16 DD2757 pKa = 3.45 ILNRR2761 pKa = 11.84 ADD2763 pKa = 3.66 NLGFLVPKK2771 pKa = 10.32 YY2772 pKa = 10.52 CLNIDD2777 pKa = 4.01 NNTDD2781 pKa = 2.96 MAIRR2785 pKa = 11.84 FSIKK2789 pKa = 9.76 HH2790 pKa = 5.26 NGQVRR2795 pKa = 11.84 VVTLGSMIPDD2805 pKa = 4.41 DD2806 pKa = 3.79 YY2807 pKa = 11.47 LVRR2810 pKa = 11.84 INNMLLASPLPVILVTSKK2828 pKa = 10.61 LHH2830 pKa = 5.7 NKK2832 pKa = 9.0 SDD2834 pKa = 3.24 KK2835 pKa = 10.38 FDD2837 pKa = 4.11 YY2838 pKa = 10.89 DD2839 pKa = 3.49 GQTFALNMPGMYY2851 pKa = 9.94 KK2852 pKa = 10.18 SICIVPSVNYY2862 pKa = 9.85 LALNNRR2868 pKa = 11.84 IVEE2871 pKa = 4.21 AHH2873 pKa = 5.66 HH2874 pKa = 6.53 HH2875 pKa = 6.37 CGAGTYY2881 pKa = 8.63 LTFRR2885 pKa = 11.84 MLGVKK2890 pKa = 8.84 QVPYY2894 pKa = 10.84 AVAFDD2899 pKa = 3.21 QHH2901 pKa = 6.83 YY2902 pKa = 10.08 NAWHH2906 pKa = 5.54 YY2907 pKa = 11.6 NKK2909 pKa = 10.39 DD2910 pKa = 3.69 AVDD2913 pKa = 4.1 SADD2916 pKa = 3.98 KK2917 pKa = 10.4 PPTSMSVEE2925 pKa = 4.01 EE2926 pKa = 3.96 QLNRR2930 pKa = 11.84 SIRR2933 pKa = 11.84 DD2934 pKa = 3.48 VQQMLDD2940 pKa = 2.85 IHH2942 pKa = 6.44 GAVTNIKK2949 pKa = 10.42 LVDD2952 pKa = 3.59 PTALGEE2958 pKa = 4.16 IPFVEE2963 pKa = 4.75 RR2964 pKa = 11.84 PIDD2967 pKa = 3.5 TNIVVKK2973 pKa = 9.46 PVILRR2978 pKa = 11.84 GVKK2981 pKa = 9.1 TIKK2984 pKa = 9.06 NTYY2987 pKa = 9.45 IDD2989 pKa = 3.31 NCVFNVLLDD2998 pKa = 3.9 CMQDD3002 pKa = 3.52 DD3003 pKa = 4.37 PACARR3008 pKa = 11.84 LVDD3011 pKa = 4.39 AACATHH3017 pKa = 6.4 TFMVPEE3023 pKa = 4.1 DD3024 pKa = 3.86 VIEE3027 pKa = 4.56 FLLTMPCNFAITFRR3041 pKa = 11.84 NTSLICDD3048 pKa = 3.33 KK3049 pKa = 10.7 KK3050 pKa = 10.94 LNVNVRR3056 pKa = 11.84 ISITDD3061 pKa = 3.7 DD3062 pKa = 3.26 LSHH3065 pKa = 8.2 AEE3067 pKa = 4.19 EE3068 pKa = 4.44 FTFDD3072 pKa = 3.23 SYY3074 pKa = 12.09 EE3075 pKa = 4.15 EE3076 pKa = 4.23 VAHH3079 pKa = 5.8 ATSDD3083 pKa = 3.39 AFNDD3087 pKa = 4.72 LIISGDD3093 pKa = 3.57 YY3094 pKa = 9.82 TRR3096 pKa = 11.84 DD3097 pKa = 3.16 VQTVVEE3103 pKa = 4.84 SISTLEE3109 pKa = 4.64 PINFDD3114 pKa = 3.43 KK3115 pKa = 11.06 VRR3117 pKa = 11.84 HH3118 pKa = 5.52 SLVLTSMRR3126 pKa = 11.84 KK3127 pKa = 9.17 LRR3129 pKa = 11.84 PLEE3132 pKa = 4.12 LFNGASGLAHH3142 pKa = 5.81 ITSSKK3147 pKa = 10.05 RR3148 pKa = 11.84 LSAGYY3153 pKa = 10.36 VYY3155 pKa = 11.12 ACLTSAGLVQALCVPSLNGNSMLVHH3180 pKa = 6.26 MQPVMYY3186 pKa = 9.46 NCAVIIRR3193 pKa = 11.84 LNKK3196 pKa = 10.46 LIDD3199 pKa = 3.49 IPVGAKK3205 pKa = 9.86 RR3206 pKa = 11.84 SLIKK3210 pKa = 8.48 TTNLVAINHH3219 pKa = 5.56 ATSLQLQTRR3228 pKa = 11.84 GIFVSSVAQPQADD3241 pKa = 3.51 TLYY3244 pKa = 10.25 IYY3246 pKa = 7.69 DD3247 pKa = 3.34 TWARR3251 pKa = 11.84 KK3252 pKa = 8.53 HH3253 pKa = 6.1 HH3254 pKa = 6.71 FEE3256 pKa = 5.32 AEE3258 pKa = 3.91 QEE3260 pKa = 4.42 TIRR3263 pKa = 11.84 TAKK3266 pKa = 10.29 RR3267 pKa = 11.84 IMAVPEE3273 pKa = 4.46 SKK3275 pKa = 10.59 DD3276 pKa = 3.42 KK3277 pKa = 10.8 PLTDD3281 pKa = 3.4 ITPQKK3286 pKa = 9.18 PTLLSKK3292 pKa = 10.65 AYY3294 pKa = 8.47 PVCIAKK3300 pKa = 10.34 GKK3302 pKa = 10.38 FYY3304 pKa = 10.52 FRR3306 pKa = 11.84 CEE3308 pKa = 3.9 SANRR3312 pKa = 11.84 ATNDD3316 pKa = 3.02 ILNSLKK3322 pKa = 10.49 FCSKK3326 pKa = 9.77 LTDD3329 pKa = 3.53 GLYY3332 pKa = 10.72 LLPYY3336 pKa = 8.43 KK3337 pKa = 10.7 SKK3339 pKa = 8.25 WTTLFTILFKK3349 pKa = 11.27 YY3350 pKa = 10.55 DD3351 pKa = 3.22 GTKK3354 pKa = 9.47 IEE3356 pKa = 4.23 YY3357 pKa = 9.86 CNTVSVDD3364 pKa = 3.42 PPTNLQEE3371 pKa = 5.39 LYY3373 pKa = 10.95 DD3374 pKa = 3.92 FTKK3377 pKa = 10.49 VDD3379 pKa = 3.34 TMAVKK3384 pKa = 10.5 LRR3386 pKa = 11.84 LEE3388 pKa = 4.28 NLSKK3392 pKa = 10.19 QHH3394 pKa = 6.58 GYY3396 pKa = 8.98 TSMAEE3401 pKa = 3.97 CRR3403 pKa = 11.84 IEE3405 pKa = 4.39 QVTTMHH3411 pKa = 6.8 TIEE3414 pKa = 4.47 TYY3416 pKa = 10.87 SLAVRR3421 pKa = 11.84 QKK3423 pKa = 9.66 LHH3425 pKa = 7.55 IEE3427 pKa = 3.8 VDD3429 pKa = 3.64 HH3430 pKa = 7.07 LITGANGWTFRR3441 pKa = 11.84 IAKK3444 pKa = 9.29 QGAGFVQFDD3453 pKa = 4.32 EE3454 pKa = 4.03 IHH3456 pKa = 6.39 IPEE3459 pKa = 4.98 LEE3461 pKa = 3.9 DD3462 pKa = 4.1 SKK3464 pKa = 11.7 FNNSKK3469 pKa = 10.32 FATPLQPTPSTTLTQDD3485 pKa = 2.99 MTALIPLDD3493 pKa = 4.48 GKK3495 pKa = 10.5 DD3496 pKa = 3.39 LSNNFVYY3503 pKa = 10.32 KK3504 pKa = 9.1 QTLNYY3509 pKa = 8.84 HH3510 pKa = 6.15 AKK3512 pKa = 8.67 EE3513 pKa = 3.96 NQLISVGNVTSLGLEE3528 pKa = 3.84 VDD3530 pKa = 4.22 AIKK3533 pKa = 10.77 YY3534 pKa = 10.48 DD3535 pKa = 4.82 EE3536 pKa = 4.86 IPQSQVIDD3544 pKa = 3.74 FWNNSEE3550 pKa = 5.05 LLDD3553 pKa = 4.29 SNIILPTNAQFTVRR3567 pKa = 11.84 SRR3569 pKa = 11.84 IQPIRR3574 pKa = 11.84 IKK3576 pKa = 10.98 SNAYY3580 pKa = 10.58 LLMEE3584 pKa = 5.79 AYY3586 pKa = 9.43 PKK3588 pKa = 10.27 FARR3591 pKa = 11.84 PSRR3594 pKa = 11.84 SKK3596 pKa = 11.34 AFAEE3600 pKa = 4.16 EE3601 pKa = 4.46 LNSITNRR3608 pKa = 11.84 HH3609 pKa = 4.51 GAYY3612 pKa = 8.95 TVFRR3616 pKa = 11.84 KK3617 pKa = 8.62 TDD3619 pKa = 3.56 LDD3621 pKa = 3.9 TKK3623 pKa = 10.82 QEE3625 pKa = 4.07 VQFLIDD3631 pKa = 3.74 NYY3633 pKa = 8.81 FTKK3636 pKa = 10.25 DD3637 pKa = 3.43 YY3638 pKa = 11.08 KK3639 pKa = 11.19 SILAEE3644 pKa = 4.13 FQNQPITFSPAKK3656 pKa = 8.95 AQAWIDD3662 pKa = 3.47 KK3663 pKa = 10.54 HH3664 pKa = 6.62 NMPKK3668 pKa = 10.16 KK3669 pKa = 9.58 VRR3671 pKa = 11.84 ADD3673 pKa = 3.49 VMEE3676 pKa = 4.06 MLATGWEE3683 pKa = 4.13 KK3684 pKa = 10.32 TPINAMSVHH3693 pKa = 6.36 GKK3695 pKa = 7.71 TEE3697 pKa = 3.72 QTTKK3701 pKa = 10.32 MKK3703 pKa = 6.66 TTRR3706 pKa = 11.84 WFDD3709 pKa = 3.64 DD3710 pKa = 3.48 VVTRR3714 pKa = 11.84 SIVAAPYY3721 pKa = 10.16 AVSALFADD3729 pKa = 4.34 IFLEE3733 pKa = 4.4 TKK3735 pKa = 10.01 QRR3737 pKa = 11.84 LKK3739 pKa = 11.09 AVLGPKK3745 pKa = 9.71 IFYY3748 pKa = 10.4 SDD3750 pKa = 3.15 GSTPLDD3756 pKa = 3.36 LAAVIRR3762 pKa = 11.84 SSDD3765 pKa = 3.42 DD3766 pKa = 3.01 FTYY3769 pKa = 10.68 CVEE3772 pKa = 5.88 DD3773 pKa = 5.74 DD3774 pKa = 3.92 LTQQDD3779 pKa = 3.83 RR3780 pKa = 11.84 QVDD3783 pKa = 3.67 HH3784 pKa = 6.39 QLIAVEE3790 pKa = 4.06 MEE3792 pKa = 4.54 LYY3794 pKa = 10.52 RR3795 pKa = 11.84 LLGVDD3800 pKa = 3.74 GNVLAFYY3807 pKa = 10.57 RR3808 pKa = 11.84 MCHH3811 pKa = 5.86 EE3812 pKa = 3.75 KK3813 pKa = 10.28 WSWKK3817 pKa = 9.01 GHH3819 pKa = 5.86 GISGVWDD3826 pKa = 3.7 AMRR3829 pKa = 11.84 LSGQVTTALGNAITNMIVHH3848 pKa = 6.14 NRR3850 pKa = 11.84 FMLRR3854 pKa = 11.84 NQNRR3858 pKa = 11.84 ISKK3861 pKa = 8.76 MLFLGDD3867 pKa = 5.3 DD3868 pKa = 3.97 IIFLMKK3874 pKa = 10.45 QEE3876 pKa = 4.18 VNISKK3881 pKa = 10.28 HH3882 pKa = 3.78 GTEE3885 pKa = 4.06 TKK3887 pKa = 10.13 EE3888 pKa = 4.07 LYY3890 pKa = 10.89 NMQSKK3895 pKa = 10.31 IISRR3899 pKa = 11.84 KK3900 pKa = 8.23 YY3901 pKa = 8.72 VGGFISMIVYY3911 pKa = 9.91 NINGDD3916 pKa = 3.76 VGICPHH3922 pKa = 6.71 FKK3924 pKa = 10.44 RR3925 pKa = 11.84 MRR3927 pKa = 11.84 HH3928 pKa = 5.15 RR3929 pKa = 11.84 FSVCNYY3935 pKa = 7.17 TYY3937 pKa = 10.64 PVDD3940 pKa = 3.99 DD3941 pKa = 4.5 TDD3943 pKa = 4.53 SKK3945 pKa = 9.71 VQSRR3949 pKa = 11.84 VLSYY3953 pKa = 11.53 LFMLGKK3959 pKa = 8.81 TKK3961 pKa = 8.46 WTTDD3965 pKa = 3.28 LVAKK3969 pKa = 9.85 MGYY3972 pKa = 9.37 SVSLPEE3978 pKa = 4.16 WYY3980 pKa = 7.94 HH3981 pKa = 5.66 TNTAITANALYY3992 pKa = 10.46 DD3993 pKa = 3.79 EE3994 pKa = 4.58 TEE3996 pKa = 3.81 EE3997 pKa = 4.17 WVVRR4001 pKa = 11.84 SHH4003 pKa = 7.37 ISALRR4008 pKa = 11.84 HH4009 pKa = 4.67 MLEE4012 pKa = 3.86 KK4013 pKa = 10.58 QVVKK4017 pKa = 10.4 RR4018 pKa = 11.84 HH4019 pKa = 5.99 KK4020 pKa = 9.8 FLTWSSVV4027 pKa = 2.82
Molecular weight: 452.23 kDa
Isoelectric point according different methods:
IPC2.protein.svr19 6.05
IPC2_protein 6.033
IPC_protein 6.122
Toseland 6.491
ProMoST 6.547
Dawson 6.465
Bjellqvist 6.478
Wikipedia 6.491
Rodwell 6.465
Grimsley 6.634
Solomon 6.465
Lehninger 6.465
Nozaki 6.766
DTASelect 6.942
Thurlkill 6.971
EMBOSS 6.927
Sillero 6.868
Patrickios 3.935
IPC_peptide 6.491
IPC2_peptide 6.781
IPC2.peptide.svr19 6.756
Protein with the highest isoelectric point:
>tr|K7RTN4|K7RTN4_9VIRU Polyprotein OS=Grapevine endophyte alphaendornavirus OX=1249676 PE=4 SV=1
MM1 pKa = 7.09 TPRR4 pKa = 11.84 RR5 pKa = 11.84 SRR7 pKa = 11.84 KK8 pKa = 7.3 YY9 pKa = 10.22 CKK11 pKa = 9.1 RR12 pKa = 11.84 TKK14 pKa = 8.9 ITHH17 pKa = 5.99 SGHH20 pKa = 5.47 YY21 pKa = 9.31 PKK23 pKa = 10.88 GSARR27 pKa = 11.84 NEE29 pKa = 3.49 IKK31 pKa = 10.61 LRR33 pKa = 11.84 SLHH36 pKa = 6.27 IYY38 pKa = 10.0 QYY40 pKa = 10.85 GIEE43 pKa = 4.44 GDD45 pKa = 3.43 HH46 pKa = 7.55 DD47 pKa = 3.83 IPKK50 pKa = 9.08 LTIHH54 pKa = 6.25 HH55 pKa = 5.77 TLKK58 pKa = 11.01 GEE60 pKa = 3.84 HH61 pKa = 5.94 QYY63 pKa = 11.03 IDD65 pKa = 3.9 TYY67 pKa = 11.42 LADD70 pKa = 3.73 QNDD73 pKa = 4.35 VINTRR78 pKa = 11.84 RR79 pKa = 11.84 LGISGVIDD87 pKa = 3.24 IFHH90 pKa = 5.93 QRR92 pKa = 11.84 KK93 pKa = 8.95 EE94 pKa = 4.16 YY95 pKa = 10.26 PVDD98 pKa = 3.37 HH99 pKa = 7.39 PYY101 pKa = 11.33 DD102 pKa = 3.61 EE103 pKa = 4.75 LTFNGNTSHH112 pKa = 6.71 VRR114 pKa = 11.84 DD115 pKa = 3.68 GLYY118 pKa = 10.93 YY119 pKa = 9.39 IDD121 pKa = 5.83 DD122 pKa = 3.63 YY123 pKa = 11.53 HH124 pKa = 9.51 GEE126 pKa = 4.03 IKK128 pKa = 9.09 PTYY131 pKa = 10.16 NFNTYY136 pKa = 9.49 RR137 pKa = 11.84 AALMDD142 pKa = 5.95 DD143 pKa = 4.04 IYY145 pKa = 11.31 KK146 pKa = 10.5 SNHH149 pKa = 3.36 VHH151 pKa = 4.82 GTKK154 pKa = 10.22 RR155 pKa = 11.84 MHH157 pKa = 6.64 TLVNWLTDD165 pKa = 3.28 KK166 pKa = 11.14 SVAFPYY172 pKa = 11.15 GNMAQKK178 pKa = 10.56 RR179 pKa = 11.84 YY180 pKa = 10.16 GYY182 pKa = 10.88 LEE184 pKa = 4.53 ALDD187 pKa = 4.72 GYY189 pKa = 9.42 YY190 pKa = 9.75 IKK192 pKa = 10.58 CAHH195 pKa = 6.95 CDD197 pKa = 3.39 CLTYY201 pKa = 10.94 LPLSTLLPPTITRR214 pKa = 11.84 AQLTQFLRR222 pKa = 11.84 EE223 pKa = 3.73 FRR225 pKa = 11.84 DD226 pKa = 3.31 QRR228 pKa = 11.84 EE229 pKa = 4.55 CYY231 pKa = 9.65 MPDD234 pKa = 3.31 PEE236 pKa = 5.02 IFGDD240 pKa = 3.67 MAMMVPMCFSTSNGNCFNCDD260 pKa = 2.69 EE261 pKa = 4.86 DD262 pKa = 6.0 LFTEE266 pKa = 4.62 TVKK269 pKa = 10.1 MAYY272 pKa = 9.86 AIYY275 pKa = 9.82 SEE277 pKa = 4.21 SFAYY281 pKa = 10.58 HH282 pKa = 4.93 NVIRR286 pKa = 11.84 GTQIEE291 pKa = 5.05 EE292 pKa = 3.92 MTKK295 pKa = 10.02 MNMLQGAPPDD305 pKa = 4.34 DD306 pKa = 3.92 MPAALSKK313 pKa = 11.17 YY314 pKa = 9.43 NEE316 pKa = 3.91 LHH318 pKa = 5.92 NRR320 pKa = 11.84 HH321 pKa = 5.89 AAKK324 pKa = 10.53 ALAKK328 pKa = 10.18 MNINHH333 pKa = 7.18 LNTIYY338 pKa = 10.39 TINDD342 pKa = 3.24 MTRR345 pKa = 11.84 TEE347 pKa = 4.02 MMSTRR352 pKa = 11.84 SHH354 pKa = 5.83 LHH356 pKa = 4.55 ITSTARR362 pKa = 11.84 INTTPMTSLEE372 pKa = 4.17 SEE374 pKa = 4.6 EE375 pKa = 4.09 ILLIGDD381 pKa = 4.52 LASATVGNLVHH392 pKa = 6.79 HH393 pKa = 7.22 PSTLVVNASLLHH405 pKa = 6.2 ICDD408 pKa = 4.67 TICNGPYY415 pKa = 10.14 FADD418 pKa = 3.18 TGITVNVPMSVEE430 pKa = 4.07 NYY432 pKa = 10.53 LEE434 pKa = 4.38 VIPAQHH440 pKa = 6.63 SFDD443 pKa = 5.15 KK444 pKa = 10.79 LINWAIDD451 pKa = 3.24 GAYY454 pKa = 9.83 IMLLRR459 pKa = 11.84 PDD461 pKa = 3.31 VSDD464 pKa = 5.13 IIVKK468 pKa = 10.02 QDD470 pKa = 2.51 ASYY473 pKa = 11.06 YY474 pKa = 7.88 YY475 pKa = 10.22 TIATGTDD482 pKa = 3.51 VLVKK486 pKa = 9.9 WDD488 pKa = 3.59 VHH490 pKa = 5.6 AHH492 pKa = 6.06 ALLANSAKK500 pKa = 10.54 YY501 pKa = 10.32 FDD503 pKa = 3.69 GANYY507 pKa = 10.14 FNIQTITHH515 pKa = 6.89 GSHH518 pKa = 5.48 LQIVKK523 pKa = 10.07 LVPADD528 pKa = 3.97 NTWHH532 pKa = 6.92 ARR534 pKa = 11.84 TLGNKK539 pKa = 7.44 PTFEE543 pKa = 3.97 ALIPVFDD550 pKa = 5.79 PINPLATLGVFGTKK564 pKa = 7.91 WEE566 pKa = 4.23 YY567 pKa = 9.57 KK568 pKa = 9.27 TINIEE573 pKa = 3.72 LLRR576 pKa = 11.84 RR577 pKa = 11.84 IVTFALTADD586 pKa = 3.93 KK587 pKa = 10.87 SSSAIEE593 pKa = 4.26 AYY595 pKa = 10.02 FAGILSTHH603 pKa = 4.89 YY604 pKa = 9.62 TIGGKK609 pKa = 9.61 VVDD612 pKa = 4.71 LTNTPITEE620 pKa = 4.31 GLPEE624 pKa = 5.55 LIYY627 pKa = 11.41 AMMILTNRR635 pKa = 11.84 KK636 pKa = 8.61 LVTMWSSILHH646 pKa = 6.18 LNNFSSSNGLEE657 pKa = 4.03 TLTKK661 pKa = 10.27 FFLSRR666 pKa = 11.84 LVKK669 pKa = 10.72 VSVQIADD676 pKa = 3.78 KK677 pKa = 10.47 VLPWFSGVLSKK688 pKa = 9.61 PTEE691 pKa = 3.73 FAKK694 pKa = 10.72 RR695 pKa = 11.84 LLSSKK700 pKa = 10.6 HH701 pKa = 6.3 PIDD704 pKa = 3.74 VDD706 pKa = 4.1 SVFAKK711 pKa = 10.6 LLPLLIITKK720 pKa = 10.3 QSDD723 pKa = 3.6 NTEE726 pKa = 4.62 PIAPPLHH733 pKa = 6.32 VLDD736 pKa = 4.57 SAICHH741 pKa = 5.88 HH742 pKa = 6.84 HH743 pKa = 6.78 SSSCNHH749 pKa = 6.39 SIGDD753 pKa = 3.85 VRR755 pKa = 11.84 CVCCGIMNANAVCACCVQHH774 pKa = 5.87 VKK776 pKa = 10.29 CRR778 pKa = 11.84 HH779 pKa = 5.04 SCQHH783 pKa = 6.05 KK784 pKa = 9.12 CTGNLHH790 pKa = 6.13 ACKK793 pKa = 10.38 SCMNNKK799 pKa = 8.95 PCNTKK804 pKa = 10.19 ARR806 pKa = 11.84 CACCNVYY813 pKa = 10.42 GCQPCPACPIMEE825 pKa = 4.63 PMQLHH830 pKa = 6.87 DD831 pKa = 4.2 VQPSSKK837 pKa = 9.44 MSIVTRR843 pKa = 11.84 LANNAMKK850 pKa = 10.68 VPVAHH855 pKa = 5.78 QQPKK859 pKa = 9.09 TITPAVQRR867 pKa = 11.84 PNLGHH872 pKa = 7.17 DD873 pKa = 3.46 ALMNVPKK880 pKa = 10.44 GGAVFKK886 pKa = 10.63 PNEE889 pKa = 3.93 TAHH892 pKa = 7.97 RR893 pKa = 11.84 MMTDD897 pKa = 3.18 YY898 pKa = 11.32 LQITRR903 pKa = 11.84 PEE905 pKa = 4.33 HH906 pKa = 7.05 IFIIDD911 pKa = 3.53 NSDD914 pKa = 3.39 LYY916 pKa = 10.87 IPMLSFTGQYY926 pKa = 9.37 YY927 pKa = 9.6 VPIQLPNPVVSNPIHH942 pKa = 6.31 GEE944 pKa = 3.97 HH945 pKa = 6.12 YY946 pKa = 10.29 CAYY949 pKa = 10.42 ACIAEE954 pKa = 4.04 QSNYY958 pKa = 7.33 TVQMLKK964 pKa = 10.73 NMHH967 pKa = 6.64 GDD969 pKa = 3.28 RR970 pKa = 11.84 HH971 pKa = 7.22 SMDD974 pKa = 3.64 VVEE977 pKa = 5.43 LRR979 pKa = 11.84 HH980 pKa = 5.74 LLKK983 pKa = 10.39 ILSLNCLLILNDD995 pKa = 3.3 THH997 pKa = 9.63 AEE999 pKa = 3.81 ILRR1002 pKa = 11.84 NGPQANNYY1010 pKa = 8.91 ILIGHH1015 pKa = 6.49 GSITDD1020 pKa = 3.99 EE1021 pKa = 4.39 VPHH1024 pKa = 6.0 AHH1026 pKa = 6.6 WFVPHH1031 pKa = 6.62 IPKK1034 pKa = 8.89 FTDD1037 pKa = 3.01 MPTGYY1042 pKa = 10.24 YY1043 pKa = 10.25 GPHH1046 pKa = 6.49 NFGQPFEE1053 pKa = 5.28 DD1054 pKa = 3.49 FTNFNMWNATTTEE1067 pKa = 4.03 MARR1070 pKa = 11.84 IQQRR1074 pKa = 11.84 LKK1076 pKa = 10.43 VLRR1079 pKa = 11.84 SQVRR1083 pKa = 11.84 HH1084 pKa = 5.44 SDD1086 pKa = 3.29 KK1087 pKa = 11.33 LGDD1090 pKa = 3.54 LALPKK1095 pKa = 10.29 VRR1097 pKa = 11.84 LIKK1100 pKa = 10.75 NVFYY1104 pKa = 9.97 LTNGDD1109 pKa = 3.3 EE1110 pKa = 4.26 HH1111 pKa = 6.38 TPRR1114 pKa = 11.84 LGKK1117 pKa = 9.69 IHH1119 pKa = 7.09 LPLPEE1124 pKa = 4.45 FVDD1127 pKa = 3.94 EE1128 pKa = 4.56 EE1129 pKa = 4.81 LVDD1132 pKa = 3.85 ALNGVDD1138 pKa = 3.78 SKK1140 pKa = 11.3 LVKK1143 pKa = 10.12 SLYY1146 pKa = 10.82 ANQTNEE1152 pKa = 3.61 WSQVRR1157 pKa = 11.84 QDD1159 pKa = 4.23 AINMFKK1165 pKa = 10.63 LRR1167 pKa = 11.84 CCDD1170 pKa = 3.14 INQLLVSDD1178 pKa = 4.52 EE1179 pKa = 4.63 ALMSPLQSYY1188 pKa = 7.6 STTVDD1193 pKa = 2.74 SDD1195 pKa = 3.81 EE1196 pKa = 4.71 PFVPVHH1202 pKa = 6.11 LLNRR1206 pKa = 11.84 VKK1208 pKa = 10.63 PLDD1211 pKa = 3.4 IVILKK1216 pKa = 10.42 KK1217 pKa = 9.95 GTQTHH1222 pKa = 5.06 TCVVAGDD1229 pKa = 3.78 ARR1231 pKa = 11.84 QPCVRR1236 pKa = 11.84 NPYY1239 pKa = 10.13 GSGVTLYY1246 pKa = 9.94 ICKK1249 pKa = 9.74 TSLSSLYY1256 pKa = 10.08 RR1257 pKa = 11.84 NLIMCVKK1264 pKa = 10.6 AINNLDD1270 pKa = 3.86 NIRR1273 pKa = 11.84 SVEE1276 pKa = 4.08 FGDD1279 pKa = 4.36 VVDD1282 pKa = 5.71 GVAGSGKK1289 pKa = 7.27 TTLLRR1294 pKa = 11.84 NLTNRR1299 pKa = 11.84 DD1300 pKa = 3.29 KK1301 pKa = 11.1 ATLVCKK1307 pKa = 9.47 TRR1309 pKa = 11.84 SAIEE1313 pKa = 3.8 SHH1315 pKa = 6.49 YY1316 pKa = 11.12 DD1317 pKa = 3.42 SSFHH1321 pKa = 6.45 TLMTMEE1327 pKa = 4.58 AAGMSHH1333 pKa = 6.93 IVTNILVIDD1342 pKa = 4.29 EE1343 pKa = 4.79 ASMITNVEE1351 pKa = 4.14 LLCCLDD1357 pKa = 3.78 NPNMLVHH1364 pKa = 6.29 MMGDD1368 pKa = 3.3 SMQIGVKK1375 pKa = 10.49 DD1376 pKa = 3.54 MSNVLGNRR1384 pKa = 11.84 KK1385 pKa = 9.23 EE1386 pKa = 4.08 NSLLAQLANTKK1397 pKa = 10.09 LYY1399 pKa = 8.27 HH1400 pKa = 6.08 TYY1402 pKa = 10.84 RR1403 pKa = 11.84 FGQPLVDD1410 pKa = 4.3 KK1411 pKa = 9.6 MLKK1414 pKa = 10.01 QFVPNITCEE1423 pKa = 4.36 PNVHH1427 pKa = 6.24 TEE1429 pKa = 4.24 LTQVTASSYY1438 pKa = 11.62 DD1439 pKa = 3.74 EE1440 pKa = 4.56 IVQLTNNYY1448 pKa = 9.36 KK1449 pKa = 9.67 VDD1451 pKa = 3.42 AVYY1454 pKa = 11.39 VFMDD1458 pKa = 3.79 ADD1460 pKa = 4.02 YY1461 pKa = 11.11 VQLLEE1466 pKa = 4.31 ILGDD1470 pKa = 3.91 KK1471 pKa = 10.44 IAVNKK1476 pKa = 9.19 VHH1478 pKa = 7.35 ASQGKK1483 pKa = 8.65 EE1484 pKa = 3.53 FDD1486 pKa = 3.67 NVLVVHH1492 pKa = 6.97 WGNFQVEE1499 pKa = 4.08 TSIVKK1504 pKa = 10.03 SSKK1507 pKa = 10.51 FLFTAATRR1515 pKa = 11.84 ARR1517 pKa = 11.84 KK1518 pKa = 8.92 HH1519 pKa = 6.17 LIWVTPKK1526 pKa = 9.49 TVNINVSKK1534 pKa = 10.79 IMDD1537 pKa = 3.42 IAYY1540 pKa = 9.42 IGSGYY1545 pKa = 10.29 EE1546 pKa = 4.03 SPHH1549 pKa = 7.3 LFDD1552 pKa = 4.95 VNEE1555 pKa = 4.04 CRR1557 pKa = 11.84 LLRR1560 pKa = 11.84 PMTEE1564 pKa = 4.02 LEE1566 pKa = 3.94 MGLIEE1571 pKa = 5.07 TILSNHH1577 pKa = 6.66 PSAIEE1582 pKa = 3.92 ANSKK1586 pKa = 8.52 FTIRR1590 pKa = 11.84 KK1591 pKa = 8.98 SSITVEE1597 pKa = 4.07 AQVKK1601 pKa = 9.64 KK1602 pKa = 9.8 WLTNINISFTVDD1614 pKa = 2.65 RR1615 pKa = 11.84 LGTHH1619 pKa = 6.78 GNNLASRR1626 pKa = 11.84 TAIDD1630 pKa = 4.05 SIKK1633 pKa = 10.99 DD1634 pKa = 3.47 GIRR1637 pKa = 11.84 ANFPAGFAQLEE1648 pKa = 4.35 SRR1650 pKa = 11.84 ISEE1653 pKa = 3.58 IMSYY1657 pKa = 10.82 SEE1659 pKa = 4.08 TSSGITSDD1667 pKa = 3.67 EE1668 pKa = 3.96 EE1669 pKa = 4.01 NAIGTLYY1676 pKa = 10.91 DD1677 pKa = 3.79 ADD1679 pKa = 4.44 AEE1681 pKa = 4.28 PVDD1684 pKa = 4.54 TNTHH1688 pKa = 4.4 TVSYY1692 pKa = 9.84 HH1693 pKa = 6.29 SYY1695 pKa = 10.29 NISIDD1700 pKa = 3.47 EE1701 pKa = 4.44 TEE1703 pKa = 4.46 QFATPPRR1710 pKa = 11.84 PDD1712 pKa = 3.13 TVRR1715 pKa = 11.84 ASDD1718 pKa = 4.07 DD1719 pKa = 3.76 RR1720 pKa = 11.84 PVPMPLSGASPQIFEE1735 pKa = 4.74 AEE1737 pKa = 4.13 SEE1739 pKa = 4.24 RR1740 pKa = 11.84 LRR1742 pKa = 11.84 KK1743 pKa = 9.95 YY1744 pKa = 10.97 LDD1746 pKa = 3.9 DD1747 pKa = 4.41 VEE1749 pKa = 4.29 QQRR1752 pKa = 11.84 LSAAPTISAAALKK1765 pKa = 8.84 NTAQATTLLQEE1776 pKa = 4.45 ALGDD1780 pKa = 3.8 ASIAEE1785 pKa = 4.32 ALPTHH1790 pKa = 6.19 MQPILTDD1797 pKa = 3.28 DD1798 pKa = 4.28 HH1799 pKa = 7.01 NPTDD1803 pKa = 3.88 SAVATVLTKK1812 pKa = 10.47 QLAHH1816 pKa = 6.11 MVRR1819 pKa = 11.84 SLPRR1823 pKa = 11.84 DD1824 pKa = 3.42 TRR1826 pKa = 11.84 GTQPTPVGAVLSTDD1840 pKa = 3.33 LAEE1843 pKa = 5.92 PIQQCLDD1850 pKa = 3.07 TRR1852 pKa = 11.84 AFGILYY1858 pKa = 9.72 KK1859 pKa = 10.78 LQVKK1863 pKa = 9.71 HH1864 pKa = 5.42 MHH1866 pKa = 6.29 LTAQLWSRR1874 pKa = 11.84 MIILADD1880 pKa = 3.13 IVLSYY1885 pKa = 11.08 QCTSTALTWKK1895 pKa = 9.91 HH1896 pKa = 5.42 QGHH1899 pKa = 7.15 LFKK1902 pKa = 11.12 LSIFGGCSLYY1912 pKa = 10.96 CGFKK1916 pKa = 10.59 FEE1918 pKa = 4.82 YY1919 pKa = 10.59 DD1920 pKa = 3.74 DD1921 pKa = 4.05 DD1922 pKa = 4.34 TVLISSAHH1930 pKa = 6.18 ADD1932 pKa = 3.58 DD1933 pKa = 5.03 TRR1935 pKa = 11.84 DD1936 pKa = 3.49 HH1937 pKa = 7.03 LLNTLNTCNRR1947 pKa = 11.84 HH1948 pKa = 4.0 ITGTTEE1954 pKa = 4.05 GIVRR1958 pKa = 11.84 VISFLSDD1965 pKa = 3.03 DD1966 pKa = 4.02 TLFGSVPRR1974 pKa = 11.84 NTCFKK1979 pKa = 10.19 TYY1981 pKa = 9.47 VEE1983 pKa = 4.74 RR1984 pKa = 11.84 LTNICGGVLTDD1995 pKa = 4.67 CSFDD1999 pKa = 3.67 SVGTRR2004 pKa = 11.84 FQTEE2008 pKa = 3.87 NTSRR2012 pKa = 11.84 AISCDD2017 pKa = 3.28 SYY2019 pKa = 11.54 SDD2021 pKa = 3.59 SFIIPTHH2028 pKa = 5.39 QRR2030 pKa = 11.84 VEE2032 pKa = 4.27 HH2033 pKa = 6.14 YY2034 pKa = 10.36 IVTTSDD2040 pKa = 4.21 GIRR2043 pKa = 11.84 LEE2045 pKa = 4.11 PCNVIVHH2052 pKa = 5.88 TAKK2055 pKa = 10.64 QLVQLFSGIRR2065 pKa = 11.84 GTDD2068 pKa = 2.86 ADD2070 pKa = 4.18 FTLSRR2075 pKa = 11.84 ANKK2078 pKa = 8.12 ATLEE2082 pKa = 4.05 KK2083 pKa = 10.66 TMIRR2087 pKa = 11.84 HH2088 pKa = 6.12 LNAEE2092 pKa = 4.32 EE2093 pKa = 4.38 KK2094 pKa = 10.3 FDD2096 pKa = 4.14 RR2097 pKa = 11.84 PVNIPTQLVRR2107 pKa = 11.84 SEE2109 pKa = 3.96 LWQTFMQQVGSNVITPIAIGTTAVSSIHH2137 pKa = 6.23 GAMLMSALMLRR2148 pKa = 11.84 QMFADD2153 pKa = 4.27 EE2154 pKa = 4.96 PIHH2157 pKa = 6.67 YY2158 pKa = 9.82 IGLNAQLFCLNYY2170 pKa = 10.17 VVGDD2174 pKa = 4.43 TISEE2178 pKa = 4.15 IPGDD2182 pKa = 3.53 GAVYY2186 pKa = 9.85 IRR2188 pKa = 11.84 QMMSAKK2194 pKa = 9.93 AAAIAALIEE2203 pKa = 4.46 GEE2205 pKa = 4.17 SDD2207 pKa = 3.09 ADD2209 pKa = 3.62 EE2210 pKa = 4.62 LKK2212 pKa = 10.79 RR2213 pKa = 11.84 LQDD2216 pKa = 3.33 EE2217 pKa = 4.21 LAIVSDD2223 pKa = 3.56 YY2224 pKa = 10.86 RR2225 pKa = 11.84 AIVASPVRR2233 pKa = 11.84 KK2234 pKa = 8.48 LTICHH2239 pKa = 6.22 PKK2241 pKa = 9.83 YY2242 pKa = 10.21 FNRR2245 pKa = 11.84 YY2246 pKa = 6.88 HH2247 pKa = 6.59 SNRR2250 pKa = 11.84 VFTCYY2255 pKa = 10.18 PYY2257 pKa = 8.44 TTDD2260 pKa = 3.55 PTCIVQDD2267 pKa = 3.76 GKK2269 pKa = 11.27 LLEE2272 pKa = 4.31 ASEE2275 pKa = 4.99 DD2276 pKa = 3.6 GGSFEE2281 pKa = 4.79 VSLDD2285 pKa = 3.23 NTVIIGVVGSYY2296 pKa = 10.95 YY2297 pKa = 7.98 MHH2299 pKa = 6.73 KK2300 pKa = 10.04 HH2301 pKa = 4.52 VEE2303 pKa = 4.1 KK2304 pKa = 10.69 LPEE2307 pKa = 3.78 ITLQSSGIANPNYY2320 pKa = 9.85 RR2321 pKa = 11.84 VFASNVPGMEE2331 pKa = 4.14 TVSIPDD2337 pKa = 3.65 TIFRR2341 pKa = 11.84 RR2342 pKa = 11.84 LVARR2346 pKa = 11.84 AFADD2350 pKa = 3.88 ADD2352 pKa = 3.87 TKK2354 pKa = 11.1 LPDD2357 pKa = 3.55 MIAYY2361 pKa = 9.52 SRR2363 pKa = 11.84 SLLNTMTYY2371 pKa = 8.63 TSKK2374 pKa = 10.99 GYY2376 pKa = 9.61 SFKK2379 pKa = 11.5 YY2380 pKa = 9.95 NDD2382 pKa = 3.95 NPLEE2386 pKa = 4.05 LLQFSIVALNFANRR2400 pKa = 11.84 QRR2402 pKa = 11.84 KK2403 pKa = 6.64 VTGFVNSVLGLGVDD2417 pKa = 3.85 TDD2419 pKa = 3.84 KK2420 pKa = 11.45 SSSYY2424 pKa = 11.36 SPIINLLVEE2433 pKa = 4.15 SLKK2436 pKa = 10.4 TIGLNLMQNQFNQPLQILHH2455 pKa = 6.49 EE2456 pKa = 4.16 MLNRR2460 pKa = 11.84 GTMEE2464 pKa = 4.06 TPVISDD2470 pKa = 3.24 IFAVLRR2476 pKa = 11.84 DD2477 pKa = 3.61 ANYY2480 pKa = 10.26 QEE2482 pKa = 5.03 IYY2484 pKa = 10.14 PSIRR2488 pKa = 11.84 LKK2490 pKa = 10.5 YY2491 pKa = 9.14 RR2492 pKa = 11.84 HH2493 pKa = 5.83 SEE2495 pKa = 3.99 RR2496 pKa = 11.84 SNQTVNSDD2504 pKa = 3.01 TAANDD2509 pKa = 3.31 NDD2511 pKa = 4.03 VDD2513 pKa = 4.01 SHH2515 pKa = 6.88 PNTDD2519 pKa = 4.05 AGDD2522 pKa = 3.79 TTDD2525 pKa = 3.35 VQTTPAVAPTPKK2537 pKa = 9.06 PDD2539 pKa = 3.47 KK2540 pKa = 10.95 GKK2542 pKa = 11.18 GPALPDD2548 pKa = 3.25 NSEE2551 pKa = 4.3 YY2552 pKa = 11.11 ASSSQTQQIAKK2563 pKa = 9.5 FFSDD2567 pKa = 3.4 KK2568 pKa = 11.21 VITTWHH2574 pKa = 6.85 DD2575 pKa = 3.04 MHH2577 pKa = 6.68 EE2578 pKa = 4.08 AWNKK2582 pKa = 8.47 YY2583 pKa = 8.15 VKK2585 pKa = 10.67 SNNQYY2590 pKa = 10.27 QPWEE2594 pKa = 4.42 FNTHH2598 pKa = 5.29 VGDD2601 pKa = 4.37 VLLLYY2606 pKa = 10.64 AGSRR2610 pKa = 11.84 GDD2612 pKa = 4.11 AQPLDD2617 pKa = 4.88 AIAEE2621 pKa = 4.28 VAVAGGLSVRR2631 pKa = 11.84 SLIPADD2637 pKa = 3.44 LHH2639 pKa = 6.74 SRR2641 pKa = 11.84 IPGVHH2646 pKa = 6.12 YY2647 pKa = 10.49 IEE2649 pKa = 5.07 YY2650 pKa = 9.71 CDD2652 pKa = 4.95 SYY2654 pKa = 11.88 DD2655 pKa = 3.96 ALTTCGVNGTIPDD2668 pKa = 3.5 ASTFMTHH2675 pKa = 6.68 AMDD2678 pKa = 5.55 VYY2680 pKa = 9.9 RR2681 pKa = 11.84 HH2682 pKa = 5.04 WLKK2685 pKa = 9.8 EE2686 pKa = 3.97 HH2687 pKa = 5.22 MRR2689 pKa = 11.84 HH2690 pKa = 6.34 RR2691 pKa = 11.84 IVIGMFFSSEE2701 pKa = 3.81 ANLVHH2706 pKa = 5.93 GTEE2709 pKa = 4.03 KK2710 pKa = 10.64 NIRR2713 pKa = 11.84 IIPQLDD2719 pKa = 3.85 DD2720 pKa = 3.62 EE2721 pKa = 4.74 WDD2723 pKa = 3.65 GAAKK2727 pKa = 10.08 CNHH2730 pKa = 5.62 GMSSNSIRR2738 pKa = 11.84 KK2739 pKa = 8.36 FFKK2742 pKa = 10.4 LPKK2745 pKa = 9.81 PVITPYY2751 pKa = 9.88 WAVPYY2756 pKa = 10.16 DD2757 pKa = 3.45 ILNRR2761 pKa = 11.84 ADD2763 pKa = 3.66 NLGFLVPKK2771 pKa = 10.32 YY2772 pKa = 10.52 CLNIDD2777 pKa = 4.01 NNTDD2781 pKa = 2.96 MAIRR2785 pKa = 11.84 FSIKK2789 pKa = 9.76 HH2790 pKa = 5.26 NGQVRR2795 pKa = 11.84 VVTLGSMIPDD2805 pKa = 4.41 DD2806 pKa = 3.79 YY2807 pKa = 11.47 LVRR2810 pKa = 11.84 INNMLLASPLPVILVTSKK2828 pKa = 10.61 LHH2830 pKa = 5.7 NKK2832 pKa = 9.0 SDD2834 pKa = 3.24 KK2835 pKa = 10.38 FDD2837 pKa = 4.11 YY2838 pKa = 10.89 DD2839 pKa = 3.49 GQTFALNMPGMYY2851 pKa = 9.94 KK2852 pKa = 10.18 SICIVPSVNYY2862 pKa = 9.85 LALNNRR2868 pKa = 11.84 IVEE2871 pKa = 4.21 AHH2873 pKa = 5.66 HH2874 pKa = 6.53 HH2875 pKa = 6.37 CGAGTYY2881 pKa = 8.63 LTFRR2885 pKa = 11.84 MLGVKK2890 pKa = 8.84 QVPYY2894 pKa = 10.84 AVAFDD2899 pKa = 3.21 QHH2901 pKa = 6.83 YY2902 pKa = 10.08 NAWHH2906 pKa = 5.54 YY2907 pKa = 11.6 NKK2909 pKa = 10.39 DD2910 pKa = 3.69 AVDD2913 pKa = 4.1 SADD2916 pKa = 3.98 KK2917 pKa = 10.4 PPTSMSVEE2925 pKa = 4.01 EE2926 pKa = 3.96 QLNRR2930 pKa = 11.84 SIRR2933 pKa = 11.84 DD2934 pKa = 3.48 VQQMLDD2940 pKa = 2.85 IHH2942 pKa = 6.44 GAVTNIKK2949 pKa = 10.42 LVDD2952 pKa = 3.59 PTALGEE2958 pKa = 4.16 IPFVEE2963 pKa = 4.75 RR2964 pKa = 11.84 PIDD2967 pKa = 3.5 TNIVVKK2973 pKa = 9.46 PVILRR2978 pKa = 11.84 GVKK2981 pKa = 9.1 TIKK2984 pKa = 9.06 NTYY2987 pKa = 9.45 IDD2989 pKa = 3.31 NCVFNVLLDD2998 pKa = 3.9 CMQDD3002 pKa = 3.52 DD3003 pKa = 4.37 PACARR3008 pKa = 11.84 LVDD3011 pKa = 4.39 AACATHH3017 pKa = 6.4 TFMVPEE3023 pKa = 4.1 DD3024 pKa = 3.86 VIEE3027 pKa = 4.56 FLLTMPCNFAITFRR3041 pKa = 11.84 NTSLICDD3048 pKa = 3.33 KK3049 pKa = 10.7 KK3050 pKa = 10.94 LNVNVRR3056 pKa = 11.84 ISITDD3061 pKa = 3.7 DD3062 pKa = 3.26 LSHH3065 pKa = 8.2 AEE3067 pKa = 4.19 EE3068 pKa = 4.44 FTFDD3072 pKa = 3.23 SYY3074 pKa = 12.09 EE3075 pKa = 4.15 EE3076 pKa = 4.23 VAHH3079 pKa = 5.8 ATSDD3083 pKa = 3.39 AFNDD3087 pKa = 4.72 LIISGDD3093 pKa = 3.57 YY3094 pKa = 9.82 TRR3096 pKa = 11.84 DD3097 pKa = 3.16 VQTVVEE3103 pKa = 4.84 SISTLEE3109 pKa = 4.64 PINFDD3114 pKa = 3.43 KK3115 pKa = 11.06 VRR3117 pKa = 11.84 HH3118 pKa = 5.52 SLVLTSMRR3126 pKa = 11.84 KK3127 pKa = 9.17 LRR3129 pKa = 11.84 PLEE3132 pKa = 4.12 LFNGASGLAHH3142 pKa = 5.81 ITSSKK3147 pKa = 10.05 RR3148 pKa = 11.84 LSAGYY3153 pKa = 10.36 VYY3155 pKa = 11.12 ACLTSAGLVQALCVPSLNGNSMLVHH3180 pKa = 6.26 MQPVMYY3186 pKa = 9.46 NCAVIIRR3193 pKa = 11.84 LNKK3196 pKa = 10.46 LIDD3199 pKa = 3.49 IPVGAKK3205 pKa = 9.86 RR3206 pKa = 11.84 SLIKK3210 pKa = 8.48 TTNLVAINHH3219 pKa = 5.56 ATSLQLQTRR3228 pKa = 11.84 GIFVSSVAQPQADD3241 pKa = 3.51 TLYY3244 pKa = 10.25 IYY3246 pKa = 7.69 DD3247 pKa = 3.34 TWARR3251 pKa = 11.84 KK3252 pKa = 8.53 HH3253 pKa = 6.1 HH3254 pKa = 6.71 FEE3256 pKa = 5.32 AEE3258 pKa = 3.91 QEE3260 pKa = 4.42 TIRR3263 pKa = 11.84 TAKK3266 pKa = 10.29 RR3267 pKa = 11.84 IMAVPEE3273 pKa = 4.46 SKK3275 pKa = 10.59 DD3276 pKa = 3.42 KK3277 pKa = 10.8 PLTDD3281 pKa = 3.4 ITPQKK3286 pKa = 9.18 PTLLSKK3292 pKa = 10.65 AYY3294 pKa = 8.47 PVCIAKK3300 pKa = 10.34 GKK3302 pKa = 10.38 FYY3304 pKa = 10.52 FRR3306 pKa = 11.84 CEE3308 pKa = 3.9 SANRR3312 pKa = 11.84 ATNDD3316 pKa = 3.02 ILNSLKK3322 pKa = 10.49 FCSKK3326 pKa = 9.77 LTDD3329 pKa = 3.53 GLYY3332 pKa = 10.72 LLPYY3336 pKa = 8.43 KK3337 pKa = 10.7 SKK3339 pKa = 8.25 WTTLFTILFKK3349 pKa = 11.27 YY3350 pKa = 10.55 DD3351 pKa = 3.22 GTKK3354 pKa = 9.47 IEE3356 pKa = 4.23 YY3357 pKa = 9.86 CNTVSVDD3364 pKa = 3.42 PPTNLQEE3371 pKa = 5.39 LYY3373 pKa = 10.95 DD3374 pKa = 3.92 FTKK3377 pKa = 10.49 VDD3379 pKa = 3.34 TMAVKK3384 pKa = 10.5 LRR3386 pKa = 11.84 LEE3388 pKa = 4.28 NLSKK3392 pKa = 10.19 QHH3394 pKa = 6.58 GYY3396 pKa = 8.98 TSMAEE3401 pKa = 3.97 CRR3403 pKa = 11.84 IEE3405 pKa = 4.39 QVTTMHH3411 pKa = 6.8 TIEE3414 pKa = 4.47 TYY3416 pKa = 10.87 SLAVRR3421 pKa = 11.84 QKK3423 pKa = 9.66 LHH3425 pKa = 7.55 IEE3427 pKa = 3.8 VDD3429 pKa = 3.64 HH3430 pKa = 7.07 LITGANGWTFRR3441 pKa = 11.84 IAKK3444 pKa = 9.29 QGAGFVQFDD3453 pKa = 4.32 EE3454 pKa = 4.03 IHH3456 pKa = 6.39 IPEE3459 pKa = 4.98 LEE3461 pKa = 3.9 DD3462 pKa = 4.1 SKK3464 pKa = 11.7 FNNSKK3469 pKa = 10.32 FATPLQPTPSTTLTQDD3485 pKa = 2.99 MTALIPLDD3493 pKa = 4.48 GKK3495 pKa = 10.5 DD3496 pKa = 3.39 LSNNFVYY3503 pKa = 10.32 KK3504 pKa = 9.1 QTLNYY3509 pKa = 8.84 HH3510 pKa = 6.15 AKK3512 pKa = 8.67 EE3513 pKa = 3.96 NQLISVGNVTSLGLEE3528 pKa = 3.84 VDD3530 pKa = 4.22 AIKK3533 pKa = 10.77 YY3534 pKa = 10.48 DD3535 pKa = 4.82 EE3536 pKa = 4.86 IPQSQVIDD3544 pKa = 3.74 FWNNSEE3550 pKa = 5.05 LLDD3553 pKa = 4.29 SNIILPTNAQFTVRR3567 pKa = 11.84 SRR3569 pKa = 11.84 IQPIRR3574 pKa = 11.84 IKK3576 pKa = 10.98 SNAYY3580 pKa = 10.58 LLMEE3584 pKa = 5.79 AYY3586 pKa = 9.43 PKK3588 pKa = 10.27 FARR3591 pKa = 11.84 PSRR3594 pKa = 11.84 SKK3596 pKa = 11.34 AFAEE3600 pKa = 4.16 EE3601 pKa = 4.46 LNSITNRR3608 pKa = 11.84 HH3609 pKa = 4.51 GAYY3612 pKa = 8.95 TVFRR3616 pKa = 11.84 KK3617 pKa = 8.62 TDD3619 pKa = 3.56 LDD3621 pKa = 3.9 TKK3623 pKa = 10.82 QEE3625 pKa = 4.07 VQFLIDD3631 pKa = 3.74 NYY3633 pKa = 8.81 FTKK3636 pKa = 10.25 DD3637 pKa = 3.43 YY3638 pKa = 11.08 KK3639 pKa = 11.19 SILAEE3644 pKa = 4.13 FQNQPITFSPAKK3656 pKa = 8.95 AQAWIDD3662 pKa = 3.47 KK3663 pKa = 10.54 HH3664 pKa = 6.62 NMPKK3668 pKa = 10.16 KK3669 pKa = 9.58 VRR3671 pKa = 11.84 ADD3673 pKa = 3.49 VMEE3676 pKa = 4.06 MLATGWEE3683 pKa = 4.13 KK3684 pKa = 10.32 TPINAMSVHH3693 pKa = 6.36 GKK3695 pKa = 7.71 TEE3697 pKa = 3.72 QTTKK3701 pKa = 10.32 MKK3703 pKa = 6.66 TTRR3706 pKa = 11.84 WFDD3709 pKa = 3.64 DD3710 pKa = 3.48 VVTRR3714 pKa = 11.84 SIVAAPYY3721 pKa = 10.16 AVSALFADD3729 pKa = 4.34 IFLEE3733 pKa = 4.4 TKK3735 pKa = 10.01 QRR3737 pKa = 11.84 LKK3739 pKa = 11.09 AVLGPKK3745 pKa = 9.71 IFYY3748 pKa = 10.4 SDD3750 pKa = 3.15 GSTPLDD3756 pKa = 3.36 LAAVIRR3762 pKa = 11.84 SSDD3765 pKa = 3.42 DD3766 pKa = 3.01 FTYY3769 pKa = 10.68 CVEE3772 pKa = 5.88 DD3773 pKa = 5.74 DD3774 pKa = 3.92 LTQQDD3779 pKa = 3.83 RR3780 pKa = 11.84 QVDD3783 pKa = 3.67 HH3784 pKa = 6.39 QLIAVEE3790 pKa = 4.06 MEE3792 pKa = 4.54 LYY3794 pKa = 10.52 RR3795 pKa = 11.84 LLGVDD3800 pKa = 3.74 GNVLAFYY3807 pKa = 10.57 RR3808 pKa = 11.84 MCHH3811 pKa = 5.86 EE3812 pKa = 3.75 KK3813 pKa = 10.28 WSWKK3817 pKa = 9.01 GHH3819 pKa = 5.86 GISGVWDD3826 pKa = 3.7 AMRR3829 pKa = 11.84 LSGQVTTALGNAITNMIVHH3848 pKa = 6.14 NRR3850 pKa = 11.84 FMLRR3854 pKa = 11.84 NQNRR3858 pKa = 11.84 ISKK3861 pKa = 8.76 MLFLGDD3867 pKa = 5.3 DD3868 pKa = 3.97 IIFLMKK3874 pKa = 10.45 QEE3876 pKa = 4.18 VNISKK3881 pKa = 10.28 HH3882 pKa = 3.78 GTEE3885 pKa = 4.06 TKK3887 pKa = 10.13 EE3888 pKa = 4.07 LYY3890 pKa = 10.89 NMQSKK3895 pKa = 10.31 IISRR3899 pKa = 11.84 KK3900 pKa = 8.23 YY3901 pKa = 8.72 VGGFISMIVYY3911 pKa = 9.91 NINGDD3916 pKa = 3.76 VGICPHH3922 pKa = 6.71 FKK3924 pKa = 10.44 RR3925 pKa = 11.84 MRR3927 pKa = 11.84 HH3928 pKa = 5.15 RR3929 pKa = 11.84 FSVCNYY3935 pKa = 7.17 TYY3937 pKa = 10.64 PVDD3940 pKa = 3.99 DD3941 pKa = 4.5 TDD3943 pKa = 4.53 SKK3945 pKa = 9.71 VQSRR3949 pKa = 11.84 VLSYY3953 pKa = 11.53 LFMLGKK3959 pKa = 8.81 TKK3961 pKa = 8.46 WTTDD3965 pKa = 3.28 LVAKK3969 pKa = 9.85 MGYY3972 pKa = 9.37 SVSLPEE3978 pKa = 4.16 WYY3980 pKa = 7.94 HH3981 pKa = 5.66 TNTAITANALYY3992 pKa = 10.46 DD3993 pKa = 3.79 EE3994 pKa = 4.58 TEE3996 pKa = 3.81 EE3997 pKa = 4.17 WVVRR4001 pKa = 11.84 SHH4003 pKa = 7.37 ISALRR4008 pKa = 11.84 HH4009 pKa = 4.67 MLEE4012 pKa = 3.86 KK4013 pKa = 10.58 QVVKK4017 pKa = 10.4 RR4018 pKa = 11.84 HH4019 pKa = 5.99 KK4020 pKa = 9.8 FLTWSSVV4027 pKa = 2.82
Molecular weight: 452.23 kDa
Isoelectric point according different methods:
IPC2.protein.svr19 6.05
IPC2_protein 6.033
IPC_protein 6.122
Toseland 6.491
ProMoST 6.547
Dawson 6.465
Bjellqvist 6.478
Wikipedia 6.491
Rodwell 6.465
Grimsley 6.634
Solomon 6.465
Lehninger 6.465
Nozaki 6.766
DTASelect 6.942
Thurlkill 6.971
EMBOSS 6.927
Sillero 6.868
Patrickios 3.935
IPC_peptide 6.491
IPC2_peptide 6.781
IPC2.peptide.svr19 6.756
Peptides (in silico digests for buttom-up proteomics)
Below you can find
in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.
Try ESI
ChTry ESI
ArgC ESI
LysN ESI
TryLysC ESI
Try MALDI
ChTry MALDI
ArgC MALDI
LysN MALDI
TryLysC MALDI
Try LTQ
ChTry LTQ
ArgC LTQ
LysN LTQ
TryLysC LTQ
Try MSlow
ChTry MSlow
ArgC MSlow
LysN MSlow
TryLysC MSlow
Try MShigh
ChTry MShigh
ArgC MShigh
LysN MShigh
TryLysC MShigh
General Statistics
Number of major isoforms
Number of additional isoforms
Number of all proteins
Number of amino acids
Min. Seq. Length
Max. Seq. Length
Avg. Seq. Length
Avg. Mol. Weight
1
0
1
4027
4027
4027
4027.0
452.23
Amino acid frequency
Ala
Cys
Asp
Glu
Phe
Gly
His
Ile
Lys
Leu
6.903 ± 0.0
2.036 ± 0.0
6.109 ± 0.0
4.296 ± 0.0
3.626 ± 0.0
4.569 ± 0.0
3.675 ± 0.0
6.879 ± 0.0
5.115 ± 0.0
9.064 ± 0.0
Met
Asn
Gln
Pro
Arg
Ser
Thr
Val
Trp
Tyr
3.054 ± 0.0
5.736 ± 0.0
4.594 ± 0.0
3.601 ± 0.0
4.346 ± 0.0
6.953 ± 0.0
7.723 ± 0.0
7.003 ± 0.0
0.919 ± 0.0
3.799 ± 0.0
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level
Most of the basic statistics you can see at this page can be downloaded from this CSV file
For dipeptide frequency statistics click here