Amino acid dipepetide frequency for Gordonia rhizosphera NBRC 16068

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	18.616AlaAla: 18.616 ± 0.165	0.953AlaCys: 0.953 ± 0.025	8.929AlaAsp: 8.929 ± 0.071	7.615AlaGlu: 7.615 ± 0.071	3.461AlaPhe: 3.461 ± 0.04	11.372AlaGly: 11.372 ± 0.079	2.691AlaHis: 2.691 ± 0.04	5.772AlaIle: 5.772 ± 0.066	2.665AlaLys: 2.665 ± 0.049	12.065AlaLeu: 12.065 ± 0.096	2.926AlaMet: 2.926 ± 0.043	2.361AlaAsn: 2.361 ± 0.038	5.869AlaPro: 5.869 ± 0.064	3.699AlaGln: 3.699 ± 0.052	8.803AlaArg: 8.803 ± 0.082	5.973AlaSer: 5.973 ± 0.06	7.692AlaThr: 7.692 ± 0.07	11.277AlaVal: 11.277 ± 0.094	1.593AlaTrp: 1.593 ± 0.03	2.286AlaTyr: 2.286 ± 0.035	0.0AlaXaa: 0.0 ± 0.0
Cys	1.069CysAla: 1.069 ± 0.026	0.109CysCys: 0.109 ± 0.007	0.544CysAsp: 0.544 ± 0.016	0.405CysGlu: 0.405 ± 0.014	0.237CysPhe: 0.237 ± 0.011	0.93CysGly: 0.93 ± 0.024	0.215CysHis: 0.215 ± 0.011	0.29CysIle: 0.29 ± 0.015	0.099CysLys: 0.099 ± 0.007	0.646CysLeu: 0.646 ± 0.018	0.129CysMet: 0.129 ± 0.009	0.165CysAsn: 0.165 ± 0.009	0.472CysPro: 0.472 ± 0.014	0.18CysGln: 0.18 ± 0.01	0.597CysArg: 0.597 ± 0.02	0.493CysSer: 0.493 ± 0.016	0.462CysThr: 0.462 ± 0.015	0.633CysVal: 0.633 ± 0.019	0.129CysTrp: 0.129 ± 0.008	0.179CysTyr: 0.179 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	8.094AspAla: 8.094 ± 0.075	0.437AspCys: 0.437 ± 0.016	5.389AspAsp: 5.389 ± 0.066	4.492AspGlu: 4.492 ± 0.052	1.812AspPhe: 1.812 ± 0.032	6.089AspGly: 6.089 ± 0.059	1.702AspHis: 1.702 ± 0.034	2.798AspIle: 2.798 ± 0.035	1.223AspLys: 1.223 ± 0.026	6.831AspLeu: 6.831 ± 0.073	1.125AspMet: 1.125 ± 0.024	1.25AspAsn: 1.25 ± 0.03	4.575AspPro: 4.575 ± 0.05	1.681AspGln: 1.681 ± 0.027	5.209AspArg: 5.209 ± 0.052	2.912AspSer: 2.912 ± 0.042	3.72AspThr: 3.72 ± 0.045	5.61AspVal: 5.61 ± 0.055	0.967AspTrp: 0.967 ± 0.022	1.378AspTyr: 1.378 ± 0.028	0.0AspXaa: 0.0 ± 0.0
Glu	5.779GluAla: 5.779 ± 0.067	0.377GluCys: 0.377 ± 0.014	2.421GluAsp: 2.421 ± 0.034	2.496GluGlu: 2.496 ± 0.042	1.88GluPhe: 1.88 ± 0.03	3.373GluGly: 3.373 ± 0.052	1.566GluHis: 1.566 ± 0.034	3.014GluIle: 3.014 ± 0.044	1.339GluLys: 1.339 ± 0.029	6.261GluLeu: 6.261 ± 0.067	1.171GluMet: 1.171 ± 0.028	1.214GluAsn: 1.214 ± 0.025	2.948GluPro: 2.948 ± 0.042	2.115GluGln: 2.115 ± 0.035	4.524GluArg: 4.524 ± 0.055	3.124GluSer: 3.124 ± 0.038	2.885GluThr: 2.885 ± 0.035	4.667GluVal: 4.667 ± 0.056	0.846GluTrp: 0.846 ± 0.019	1.166GluTyr: 1.166 ± 0.026	0.0GluXaa: 0.0 ± 0.0
Phe	4.096PheAla: 4.096 ± 0.053	0.316PheCys: 0.316 ± 0.012	2.566PheAsp: 2.566 ± 0.037	1.545PheGlu: 1.545 ± 0.031	0.967PhePhe: 0.967 ± 0.022	3.493PheGly: 3.493 ± 0.05	0.661PheHis: 0.661 ± 0.02	1.079PheIle: 1.079 ± 0.027	0.445PheLys: 0.445 ± 0.017	2.563PheLeu: 2.563 ± 0.045	0.511PheMet: 0.511 ± 0.015	0.64PheAsn: 0.64 ± 0.02	1.389PhePro: 1.389 ± 0.025	0.578PheGln: 0.578 ± 0.016	1.811PheArg: 1.811 ± 0.029	1.673PheSer: 1.673 ± 0.03	2.03PheThr: 2.03 ± 0.031	2.699PheVal: 2.699 ± 0.038	0.426PheTrp: 0.426 ± 0.016	0.701PheTyr: 0.701 ± 0.021	0.0PheXaa: 0.0 ± 0.0
Gly	9.932GlyAla: 9.932 ± 0.079	0.8GlyCys: 0.8 ± 0.022	5.298GlyAsp: 5.298 ± 0.055	4.489GlyGlu: 4.489 ± 0.056	3.172GlyPhe: 3.172 ± 0.045	7.677GlyGly: 7.677 ± 0.083	2.227GlyHis: 2.227 ± 0.032	4.337GlyIle: 4.337 ± 0.055	2.207GlyLys: 2.207 ± 0.039	8.475GlyLeu: 8.475 ± 0.077	2.125GlyMet: 2.125 ± 0.034	1.835GlyAsn: 1.835 ± 0.029	4.462GlyPro: 4.462 ± 0.052	2.634GlyGln: 2.634 ± 0.044	6.526GlyArg: 6.526 ± 0.06	5.258GlySer: 5.258 ± 0.061	5.51GlyThr: 5.51 ± 0.057	7.836GlyVal: 7.836 ± 0.068	1.592GlyTrp: 1.592 ± 0.03	2.376GlyTyr: 2.376 ± 0.037	0.0GlyXaa: 0.0 ± 0.0
His	2.532HisAla: 2.532 ± 0.036	0.198HisCys: 0.198 ± 0.01	1.501HisAsp: 1.501 ± 0.03	1.12HisGlu: 1.12 ± 0.027	0.68HisPhe: 0.68 ± 0.018	2.143HisGly: 2.143 ± 0.035	0.771HisHis: 0.771 ± 0.018	0.92HisIle: 0.92 ± 0.021	0.365HisLys: 0.365 ± 0.015	2.28HisLeu: 2.28 ± 0.04	0.391HisMet: 0.391 ± 0.015	0.487HisAsn: 0.487 ± 0.016	1.736HisPro: 1.736 ± 0.029	0.644HisGln: 0.644 ± 0.016	2.038HisArg: 2.038 ± 0.031	1.114HisSer: 1.114 ± 0.024	1.301HisThr: 1.301 ± 0.025	1.774HisVal: 1.774 ± 0.032	0.345HisTrp: 0.345 ± 0.013	0.505HisTyr: 0.505 ± 0.016	0.0HisXaa: 0.0 ± 0.0
Ile	6.797IleAla: 6.797 ± 0.068	0.406IleCys: 0.406 ± 0.015	3.842IleAsp: 3.842 ± 0.046	2.8IleGlu: 2.8 ± 0.039	1.063IlePhe: 1.063 ± 0.025	4.858IleGly: 4.858 ± 0.05	0.872IleHis: 0.872 ± 0.018	1.732IleIle: 1.732 ± 0.033	0.805IleLys: 0.805 ± 0.023	3.491IleLeu: 3.491 ± 0.041	0.698IleMet: 0.698 ± 0.02	1.087IleAsn: 1.087 ± 0.025	2.549IlePro: 2.549 ± 0.036	0.837IleGln: 0.837 ± 0.021	3.012IleArg: 3.012 ± 0.039	2.493IleSer: 2.493 ± 0.036	3.061IleThr: 3.061 ± 0.042	4.193IleVal: 4.193 ± 0.053	0.524IleTrp: 0.524 ± 0.017	0.82IleTyr: 0.82 ± 0.02	0.0IleXaa: 0.0 ± 0.0
Lys	2.44LysAla: 2.44 ± 0.047	0.124LysCys: 0.124 ± 0.007	1.0LysAsp: 1.0 ± 0.025	0.923LysGlu: 0.923 ± 0.024	0.523LysPhe: 0.523 ± 0.017	1.5LysGly: 1.5 ± 0.03	0.46LysHis: 0.46 ± 0.016	1.023LysIle: 1.023 ± 0.026	0.644LysLys: 0.644 ± 0.027	1.947LysLeu: 1.947 ± 0.036	0.44LysMet: 0.44 ± 0.016	0.493LysAsn: 0.493 ± 0.019	1.265LysPro: 1.265 ± 0.027	0.685LysGln: 0.685 ± 0.02	1.521LysArg: 1.521 ± 0.03	1.176LysSer: 1.176 ± 0.026	1.334LysThr: 1.334 ± 0.03	1.852LysVal: 1.852 ± 0.032	0.307LysTrp: 0.307 ± 0.013	0.486LysTyr: 0.486 ± 0.016	0.0LysXaa: 0.0 ± 0.0
Leu	13.194LeuAla: 13.194 ± 0.106	0.795LeuCys: 0.795 ± 0.021	6.912LeuAsp: 6.912 ± 0.071	4.391LeuGlu: 4.391 ± 0.052	2.652LeuPhe: 2.652 ± 0.042	8.726LeuGly: 8.726 ± 0.07	1.991LeuHis: 1.991 ± 0.033	4.357LeuIle: 4.357 ± 0.049	1.617LeuLys: 1.617 ± 0.031	8.807LeuLeu: 8.807 ± 0.084	1.721LeuMet: 1.721 ± 0.034	1.888LeuAsn: 1.888 ± 0.036	5.399LeuPro: 5.399 ± 0.061	2.176LeuGln: 2.176 ± 0.037	7.288LeuArg: 7.288 ± 0.059	5.579LeuSer: 5.579 ± 0.054	6.39LeuThr: 6.39 ± 0.058	8.312LeuVal: 8.312 ± 0.077	1.178LeuTrp: 1.178 ± 0.023	1.658LeuTyr: 1.658 ± 0.031	0.0LeuXaa: 0.0 ± 0.0
Met	2.521MetAla: 2.521 ± 0.037	0.202MetCys: 0.202 ± 0.01	0.902MetAsp: 0.902 ± 0.022	0.771MetGlu: 0.771 ± 0.023	0.678MetPhe: 0.678 ± 0.02	1.585MetGly: 1.585 ± 0.031	0.454MetHis: 0.454 ± 0.015	1.04MetIle: 1.04 ± 0.022	0.448MetLys: 0.448 ± 0.017	2.063MetLeu: 2.063 ± 0.039	0.452MetMet: 0.452 ± 0.017	0.527MetAsn: 0.527 ± 0.016	1.197MetPro: 1.197 ± 0.026	0.57MetGln: 0.57 ± 0.018	1.586MetArg: 1.586 ± 0.028	1.738MetSer: 1.738 ± 0.027	2.014MetThr: 2.014 ± 0.033	1.713MetVal: 1.713 ± 0.028	0.253MetTrp: 0.253 ± 0.013	0.329MetTyr: 0.329 ± 0.013	0.0MetXaa: 0.0 ± 0.0
Asn	2.463AsnAla: 2.463 ± 0.04	0.172AsnCys: 0.172 ± 0.01	1.199AsnAsp: 1.199 ± 0.028	0.975AsnGlu: 0.975 ± 0.023	0.626AsnPhe: 0.626 ± 0.018	2.011AsnGly: 2.011 ± 0.037	0.451AsnHis: 0.451 ± 0.017	0.933AsnIle: 0.933 ± 0.023	0.429AsnLys: 0.429 ± 0.015	2.005AsnLeu: 2.005 ± 0.035	0.398AsnMet: 0.398 ± 0.014	0.506AsnAsn: 0.506 ± 0.018	1.699AsnPro: 1.699 ± 0.031	0.574AsnGln: 0.574 ± 0.017	1.558AsnArg: 1.558 ± 0.026	1.083AsnSer: 1.083 ± 0.026	1.314AsnThr: 1.314 ± 0.03	1.701AsnVal: 1.701 ± 0.03	0.357AsnTrp: 0.357 ± 0.015	0.491AsnTyr: 0.491 ± 0.017	0.0AsnXaa: 0.0 ± 0.0
Pro	6.784ProAla: 6.784 ± 0.063	0.27ProCys: 0.27 ± 0.012	4.732ProAsp: 4.732 ± 0.055	3.614ProGlu: 3.614 ± 0.045	1.608ProPhe: 1.608 ± 0.03	5.379ProGly: 5.379 ± 0.051	1.214ProHis: 1.214 ± 0.024	2.35ProIle: 2.35 ± 0.037	1.164ProLys: 1.164 ± 0.027	4.541ProLeu: 4.541 ± 0.045	1.252ProMet: 1.252 ± 0.027	1.19ProAsn: 1.19 ± 0.027	2.916ProPro: 2.916 ± 0.052	1.504ProGln: 1.504 ± 0.031	3.497ProArg: 3.497 ± 0.042	3.124ProSer: 3.124 ± 0.042	3.887ProThr: 3.887 ± 0.049	4.913ProVal: 4.913 ± 0.047	0.785ProTrp: 0.785 ± 0.021	1.114ProTyr: 1.114 ± 0.026	0.0ProXaa: 0.0 ± 0.0
Gln	3.119GlnAla: 3.119 ± 0.045	0.209GlnCys: 0.209 ± 0.012	1.08GlnAsp: 1.08 ± 0.023	1.074GlnGlu: 1.074 ± 0.024	0.881GlnPhe: 0.881 ± 0.022	1.84GlnGly: 1.84 ± 0.034	0.624GlnHis: 0.624 ± 0.017	1.601GlnIle: 1.601 ± 0.03	0.602GlnLys: 0.602 ± 0.017	2.852GlnLeu: 2.852 ± 0.04	0.691GlnMet: 0.691 ± 0.019	0.562GlnAsn: 0.562 ± 0.018	1.541GlnPro: 1.541 ± 0.033	1.109GlnGln: 1.109 ± 0.029	2.469GlnArg: 2.469 ± 0.035	1.486GlnSer: 1.486 ± 0.027	1.656GlnThr: 1.656 ± 0.027	2.417GlnVal: 2.417 ± 0.04	0.523GlnTrp: 0.523 ± 0.017	0.57GlnTyr: 0.57 ± 0.021	0.0GlnXaa: 0.0 ± 0.0
Arg	8.377ArgAla: 8.377 ± 0.071	0.599ArgCys: 0.599 ± 0.018	4.606ArgAsp: 4.606 ± 0.056	3.996ArgGlu: 3.996 ± 0.044	2.458ArgPhe: 2.458 ± 0.035	5.171ArgGly: 5.171 ± 0.053	1.913ArgHis: 1.913 ± 0.032	3.69ArgIle: 3.69 ± 0.042	1.581ArgLys: 1.581 ± 0.034	7.328ArgLeu: 7.328 ± 0.069	1.849ArgMet: 1.849 ± 0.033	1.606ArgAsn: 1.606 ± 0.028	4.026ArgPro: 4.026 ± 0.045	2.051ArgGln: 2.051 ± 0.035	6.825ArgArg: 6.825 ± 0.078	4.427ArgSer: 4.427 ± 0.05	4.471ArgThr: 4.471 ± 0.05	5.855ArgVal: 5.855 ± 0.058	1.353ArgTrp: 1.353 ± 0.027	1.862ArgTyr: 1.862 ± 0.031	0.0ArgXaa: 0.0 ± 0.0
Ser	7.071SerAla: 7.071 ± 0.063	0.443SerCys: 0.443 ± 0.017	3.548SerAsp: 3.548 ± 0.049	2.716SerGlu: 2.716 ± 0.043	1.677SerPhe: 1.677 ± 0.031	5.825SerGly: 5.825 ± 0.064	1.07SerHis: 1.07 ± 0.026	2.401SerIle: 2.401 ± 0.037	1.062SerLys: 1.062 ± 0.026	4.859SerLeu: 4.859 ± 0.054	1.417SerMet: 1.417 ± 0.031	1.049SerAsn: 1.049 ± 0.022	3.149SerPro: 3.149 ± 0.043	1.367SerGln: 1.367 ± 0.023	3.76SerArg: 3.76 ± 0.045	3.474SerSer: 3.474 ± 0.053	3.67SerThr: 3.67 ± 0.045	4.992SerVal: 4.992 ± 0.058	0.889SerTrp: 0.889 ± 0.019	1.192SerTyr: 1.192 ± 0.029	0.0SerXaa: 0.0 ± 0.0
Thr	8.033ThrAla: 8.033 ± 0.072	0.433ThrCys: 0.433 ± 0.015	4.414ThrAsp: 4.414 ± 0.041	3.33ThrGlu: 3.33 ± 0.047	1.861ThrPhe: 1.861 ± 0.031	6.143ThrGly: 6.143 ± 0.06	1.296ThrHis: 1.296 ± 0.025	2.904ThrIle: 2.904 ± 0.04	1.243ThrLys: 1.243 ± 0.03	5.67ThrLeu: 5.67 ± 0.06	1.373ThrMet: 1.373 ± 0.025	1.274ThrAsn: 1.274 ± 0.027	4.061ThrPro: 4.061 ± 0.053	1.478ThrGln: 1.478 ± 0.028	4.039ThrArg: 4.039 ± 0.051	3.578ThrSer: 3.578 ± 0.042	4.537ThrThr: 4.537 ± 0.054	6.077ThrVal: 6.077 ± 0.054	0.842ThrTrp: 0.842 ± 0.022	1.287ThrTyr: 1.287 ± 0.025	0.0ThrXaa: 0.0 ± 0.0
Val	11.826ValAla: 11.826 ± 0.089	0.776ValCys: 0.776 ± 0.022	6.288ValAsp: 6.288 ± 0.063	4.729ValGlu: 4.729 ± 0.053	2.688ValPhe: 2.688 ± 0.046	7.534ValGly: 7.534 ± 0.062	1.813ValHis: 1.813 ± 0.035	4.349ValIle: 4.349 ± 0.05	1.549ValLys: 1.549 ± 0.03	8.398ValLeu: 8.398 ± 0.082	1.707ValMet: 1.707 ± 0.03	1.965ValAsn: 1.965 ± 0.033	4.661ValPro: 4.661 ± 0.05	1.819ValGln: 1.819 ± 0.032	5.858ValArg: 5.858 ± 0.059	4.88ValSer: 4.88 ± 0.058	5.809ValThr: 5.809 ± 0.056	9.021ValVal: 9.021 ± 0.074	1.076ValTrp: 1.076 ± 0.022	1.539ValTyr: 1.539 ± 0.029	0.0ValXaa: 0.0 ± 0.0
Trp	1.532TrpAla: 1.532 ± 0.03	0.143TrpCys: 0.143 ± 0.009	0.799TrpAsp: 0.799 ± 0.022	0.643TrpGlu: 0.643 ± 0.02	0.553TrpPhe: 0.553 ± 0.017	1.07TrpGly: 1.07 ± 0.023	0.361TrpHis: 0.361 ± 0.014	0.676TrpIle: 0.676 ± 0.02	0.317TrpLys: 0.317 ± 0.013	1.64TrpLeu: 1.64 ± 0.034	0.363TrpMet: 0.363 ± 0.014	0.39TrpAsn: 0.39 ± 0.012	0.749TrpPro: 0.749 ± 0.018	0.553TrpGln: 0.553 ± 0.016	1.231TrpArg: 1.231 ± 0.024	0.936TrpSer: 0.936 ± 0.025	0.915TrpThr: 0.915 ± 0.019	1.117TrpVal: 1.117 ± 0.022	0.359TrpTrp: 0.359 ± 0.016	0.352TrpTyr: 0.352 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.341TyrAla: 2.341 ± 0.038	0.222TyrCys: 0.222 ± 0.012	1.326TyrAsp: 1.326 ± 0.03	1.041TyrGlu: 1.041 ± 0.024	0.712TyrPhe: 0.712 ± 0.023	2.051TyrGly: 2.051 ± 0.034	0.494TyrHis: 0.494 ± 0.015	0.674TyrIle: 0.674 ± 0.02	0.341TyrLys: 0.341 ± 0.014	2.309TyrLeu: 2.309 ± 0.034	0.304TyrMet: 0.304 ± 0.013	0.457TyrAsn: 0.457 ± 0.016	1.177TyrPro: 1.177 ± 0.025	0.648TyrGln: 0.648 ± 0.021	1.892TyrArg: 1.892 ± 0.032	1.111TyrSer: 1.111 ± 0.024	1.214TyrThr: 1.214 ± 0.026	1.625TyrVal: 1.625 ± 0.03	0.353TyrTrp: 0.353 ± 0.014	0.474TyrTyr: 0.474 ± 0.017	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5930 proteins (1941780 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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