Amino acid dipepetide frequency for Euphorbia leaf curl Guangxi virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.364AlaAla: 6.364 ± 2.648
1.818AlaCys: 1.818 ± 1.146
0.909AlaAsp: 0.909 ± 0.735
0.909AlaGlu: 0.909 ± 0.67
0.909AlaPhe: 0.909 ± 1.064
0.909AlaGly: 0.909 ± 0.735
1.818AlaHis: 1.818 ± 1.073
2.727AlaIle: 2.727 ± 1.015
5.455AlaLys: 5.455 ± 1.236
4.545AlaLeu: 4.545 ± 1.716
0.0AlaMet: 0.0 ± 0.0
4.545AlaAsn: 4.545 ± 2.285
4.545AlaPro: 4.545 ± 1.157
1.818AlaGln: 1.818 ± 1.073
3.636AlaArg: 3.636 ± 1.969
4.545AlaSer: 4.545 ± 2.117
4.545AlaThr: 4.545 ± 1.989
0.0AlaVal: 0.0 ± 0.0
0.909AlaTrp: 0.909 ± 0.67
1.818AlaTyr: 1.818 ± 1.34
0.0AlaXaa: 0.0 ± 0.0
Cys
0.909CysAla: 0.909 ± 1.064
1.818CysCys: 1.818 ± 2.13
0.0CysAsp: 0.0 ± 0.0
1.818CysGlu: 1.818 ± 1.146
0.909CysPhe: 0.909 ± 1.009
1.818CysGly: 1.818 ± 1.029
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.909CysLys: 0.909 ± 0.735
1.818CysLeu: 1.818 ± 1.208
2.727CysMet: 2.727 ± 1.845
2.727CysAsn: 2.727 ± 1.211
2.727CysPro: 2.727 ± 2.03
1.818CysGln: 1.818 ± 1.34
0.909CysArg: 0.909 ± 0.67
1.818CysSer: 1.818 ± 1.029
0.909CysThr: 0.909 ± 0.735
0.909CysVal: 0.909 ± 0.735
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.636AspAla: 3.636 ± 1.822
0.909AspCys: 0.909 ± 1.064
0.909AspAsp: 0.909 ± 0.67
0.909AspGlu: 0.909 ± 0.735
2.727AspPhe: 2.727 ± 0.979
3.636AspGly: 3.636 ± 1.899
1.818AspHis: 1.818 ± 0.755
2.727AspIle: 2.727 ± 1.64
0.0AspLys: 0.0 ± 0.0
7.273AspLeu: 7.273 ± 4.035
0.0AspMet: 0.0 ± 0.0
2.727AspAsn: 2.727 ± 1.423
2.727AspPro: 2.727 ± 1.216
1.818AspGln: 1.818 ± 1.14
2.727AspArg: 2.727 ± 1.331
4.545AspSer: 4.545 ± 1.417
0.909AspThr: 0.909 ± 1.065
7.273AspVal: 7.273 ± 1.874
1.818AspTrp: 1.818 ± 1.34
0.909AspTyr: 0.909 ± 1.065
0.0AspXaa: 0.0 ± 0.0
Glu
4.545GluAla: 4.545 ± 1.708
0.0GluCys: 0.0 ± 0.0
2.727GluAsp: 2.727 ± 1.476
8.182GluGlu: 8.182 ± 4.182
2.727GluPhe: 2.727 ± 1.517
3.636GluGly: 3.636 ± 1.822
0.0GluHis: 0.0 ± 0.0
0.909GluIle: 0.909 ± 1.065
3.636GluLys: 3.636 ± 1.977
4.545GluLeu: 4.545 ± 1.623
0.0GluMet: 0.0 ± 0.0
4.545GluAsn: 4.545 ± 2.009
1.818GluPro: 1.818 ± 0.755
0.909GluGln: 0.909 ± 0.735
0.909GluArg: 0.909 ± 1.009
1.818GluSer: 1.818 ± 1.387
3.636GluThr: 3.636 ± 1.61
1.818GluVal: 1.818 ± 1.14
0.909GluTrp: 0.909 ± 1.064
1.818GluTyr: 1.818 ± 1.041
0.0GluXaa: 0.0 ± 0.0
Phe
0.909PheAla: 0.909 ± 0.67
0.909PheCys: 0.909 ± 0.735
3.636PheAsp: 3.636 ± 1.51
0.909PheGlu: 0.909 ± 0.67
0.909PhePhe: 0.909 ± 0.67
0.909PheGly: 0.909 ± 1.064
2.727PheHis: 2.727 ± 1.437
1.818PheIle: 1.818 ± 1.34
2.727PheLys: 2.727 ± 1.431
6.364PheLeu: 6.364 ± 2.604
0.909PheMet: 0.909 ± 0.67
3.636PheAsn: 3.636 ± 2.994
0.909PhePro: 0.909 ± 1.065
5.455PheGln: 5.455 ± 1.937
4.545PheArg: 4.545 ± 2.346
2.727PheSer: 2.727 ± 2.404
0.909PheThr: 0.909 ± 1.064
2.727PheVal: 2.727 ± 1.223
0.909PheTrp: 0.909 ± 0.735
1.818PheTyr: 1.818 ± 1.471
0.0PheXaa: 0.0 ± 0.0
Gly
2.727GlyAla: 2.727 ± 1.437
2.727GlyCys: 2.727 ± 0.992
1.818GlyAsp: 1.818 ± 1.34
0.909GlyGlu: 0.909 ± 1.009
1.818GlyPhe: 1.818 ± 1.408
2.727GlyGly: 2.727 ± 1.223
1.818GlyHis: 1.818 ± 0.755
3.636GlyIle: 3.636 ± 2.029
6.364GlyLys: 6.364 ± 2.767
1.818GlyLeu: 1.818 ± 1.208
0.909GlyMet: 0.909 ± 0.645
0.909GlyAsn: 0.909 ± 1.064
3.636GlyPro: 3.636 ± 1.217
3.636GlyGln: 3.636 ± 1.809
0.909GlyArg: 0.909 ± 0.67
2.727GlySer: 2.727 ± 2.01
0.909GlyThr: 0.909 ± 0.735
3.636GlyVal: 3.636 ± 1.839
0.0GlyTrp: 0.0 ± 0.0
0.909GlyTyr: 0.909 ± 1.065
0.0GlyXaa: 0.0 ± 0.0
His
0.909HisAla: 0.909 ± 0.735
2.727HisCys: 2.727 ± 1.216
0.909HisAsp: 0.909 ± 1.009
1.818HisGlu: 1.818 ± 1.041
2.727HisPhe: 2.727 ± 1.437
2.727HisGly: 2.727 ± 1.216
1.818HisHis: 1.818 ± 1.387
1.818HisIle: 1.818 ± 1.495
0.909HisLys: 0.909 ± 1.065
1.818HisLeu: 1.818 ± 1.34
1.818HisMet: 1.818 ± 1.208
3.636HisAsn: 3.636 ± 1.382
0.909HisPro: 0.909 ± 0.67
3.636HisGln: 3.636 ± 1.071
3.636HisArg: 3.636 ± 2.431
2.727HisSer: 2.727 ± 1.585
2.727HisThr: 2.727 ± 1.637
3.636HisVal: 3.636 ± 1.076
0.0HisTrp: 0.0 ± 0.0
0.909HisTyr: 0.909 ± 0.67
0.0HisXaa: 0.0 ± 0.0
Ile
0.909IleAla: 0.909 ± 1.064
1.818IleCys: 1.818 ± 0.755
2.727IleAsp: 2.727 ± 1.372
0.909IleGlu: 0.909 ± 0.67
3.636IlePhe: 3.636 ± 1.382
0.909IleGly: 0.909 ± 0.735
0.909IleHis: 0.909 ± 1.009
2.727IleIle: 2.727 ± 2.03
4.545IleLys: 4.545 ± 1.031
1.818IleLeu: 1.818 ± 1.073
2.727IleMet: 2.727 ± 1.837
2.727IleAsn: 2.727 ± 1.431
0.909IlePro: 0.909 ± 0.67
7.273IleGln: 7.273 ± 2.337
5.455IleArg: 5.455 ± 1.295
2.727IleSer: 2.727 ± 2.467
3.636IleThr: 3.636 ± 1.978
2.727IleVal: 2.727 ± 1.331
1.818IleTrp: 1.818 ± 1.146
1.818IleTyr: 1.818 ± 1.495
0.0IleXaa: 0.0 ± 0.0
Lys
6.364LysAla: 6.364 ± 2.519
0.909LysCys: 0.909 ± 0.67
1.818LysAsp: 1.818 ± 1.34
5.455LysGlu: 5.455 ± 2.282
4.545LysPhe: 4.545 ± 1.716
0.909LysGly: 0.909 ± 0.67
2.727LysHis: 2.727 ± 1.354
1.818LysIle: 1.818 ± 1.146
4.545LysLys: 4.545 ± 2.134
0.0LysLeu: 0.0 ± 0.0
0.0LysMet: 0.0 ± 0.0
8.182LysAsn: 8.182 ± 1.998
3.636LysPro: 3.636 ± 1.078
1.818LysGln: 1.818 ± 1.659
2.727LysArg: 2.727 ± 2.206
6.364LysSer: 6.364 ± 1.859
3.636LysThr: 3.636 ± 2.285
6.364LysVal: 6.364 ± 3.392
0.0LysTrp: 0.0 ± 0.0
3.636LysTyr: 3.636 ± 1.076
0.0LysXaa: 0.0 ± 0.0
Leu
1.818LeuAla: 1.818 ± 1.408
1.818LeuCys: 1.818 ± 1.34
5.455LeuAsp: 5.455 ± 2.203
5.455LeuGlu: 5.455 ± 2.453
0.0LeuPhe: 0.0 ± 0.0
3.636LeuGly: 3.636 ± 1.983
1.818LeuHis: 1.818 ± 1.34
5.455LeuIle: 5.455 ± 2.282
6.364LeuLys: 6.364 ± 2.072
4.545LeuLeu: 4.545 ± 1.948
0.0LeuMet: 0.0 ± 0.0
4.545LeuAsn: 4.545 ± 1.708
1.818LeuPro: 1.818 ± 1.555
3.636LeuGln: 3.636 ± 1.433
3.636LeuArg: 3.636 ± 2.119
3.636LeuSer: 3.636 ± 1.822
6.364LeuThr: 6.364 ± 1.213
2.727LeuVal: 2.727 ± 2.144
0.909LeuTrp: 0.909 ± 1.009
4.545LeuTyr: 4.545 ± 1.368
0.0LeuXaa: 0.0 ± 0.0
Met
0.909MetAla: 0.909 ± 0.735
0.0MetCys: 0.0 ± 0.0
1.818MetAsp: 1.818 ± 1.146
2.727MetGlu: 2.727 ± 2.188
1.818MetPhe: 1.818 ± 1.471
3.636MetGly: 3.636 ± 1.334
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.909MetLys: 0.909 ± 1.009
1.818MetLeu: 1.818 ± 1.659
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
1.818MetPro: 1.818 ± 1.14
0.0MetGln: 0.0 ± 0.0
1.818MetArg: 1.818 ± 2.128
1.818MetSer: 1.818 ± 1.208
0.0MetThr: 0.0 ± 0.0
0.0MetVal: 0.0 ± 0.0
1.818MetTrp: 1.818 ± 1.073
1.818MetTyr: 1.818 ± 1.471
0.0MetXaa: 0.0 ± 0.0
Asn
2.727AsnAla: 2.727 ± 1.223
0.0AsnCys: 0.0 ± 0.0
5.455AsnAsp: 5.455 ± 1.91
2.727AsnGlu: 2.727 ± 1.015
0.909AsnPhe: 0.909 ± 0.735
0.0AsnGly: 0.0 ± 0.0
8.182AsnHis: 8.182 ± 4.059
3.636AsnIle: 3.636 ± 1.226
1.818AsnLys: 1.818 ± 0.755
5.455AsnLeu: 5.455 ± 2.351
0.909AsnMet: 0.909 ± 0.655
2.727AsnAsn: 2.727 ± 0.979
2.727AsnPro: 2.727 ± 0.979
1.818AsnGln: 1.818 ± 1.029
1.818AsnArg: 1.818 ± 0.755
7.273AsnSer: 7.273 ± 3.206
5.455AsnThr: 5.455 ± 1.798
3.636AsnVal: 3.636 ± 1.226
0.909AsnTrp: 0.909 ± 0.67
1.818AsnTyr: 1.818 ± 1.34
0.0AsnXaa: 0.0 ± 0.0
Pro
1.818ProAla: 1.818 ± 1.471
1.818ProCys: 1.818 ± 1.197
2.727ProAsp: 2.727 ± 1.445
2.727ProGlu: 2.727 ± 1.216
1.818ProPhe: 1.818 ± 1.041
0.909ProGly: 0.909 ± 0.67
4.545ProHis: 4.545 ± 2.566
2.727ProIle: 2.727 ± 3.192
4.545ProLys: 4.545 ± 2.575
4.545ProLeu: 4.545 ± 2.081
1.818ProMet: 1.818 ± 1.132
4.545ProAsn: 4.545 ± 1.641
1.818ProPro: 1.818 ± 1.14
4.545ProGln: 4.545 ± 2.353
5.455ProArg: 5.455 ± 2.597
5.455ProSer: 5.455 ± 2.112
4.545ProThr: 4.545 ± 1.685
4.545ProVal: 4.545 ± 1.886
0.909ProTrp: 0.909 ± 0.67
0.909ProTyr: 0.909 ± 0.735
0.0ProXaa: 0.0 ± 0.0
Gln
2.727GlnAla: 2.727 ± 1.705
2.727GlnCys: 2.727 ± 3.027
2.727GlnAsp: 2.727 ± 2.259
2.727GlnGlu: 2.727 ± 1.223
2.727GlnPhe: 2.727 ± 1.431
2.727GlnGly: 2.727 ± 1.517
2.727GlnHis: 2.727 ± 2.404
3.636GlnIle: 3.636 ± 2.082
2.727GlnLys: 2.727 ± 2.259
2.727GlnLeu: 2.727 ± 1.517
0.909GlnMet: 0.909 ± 1.148
1.818GlnAsn: 1.818 ± 1.34
6.364GlnPro: 6.364 ± 3.237
0.909GlnGln: 0.909 ± 0.735
1.818GlnArg: 1.818 ± 1.14
5.455GlnSer: 5.455 ± 1.653
0.909GlnThr: 0.909 ± 1.009
3.636GlnVal: 3.636 ± 1.35
0.0GlnTrp: 0.0 ± 0.0
0.909GlnTyr: 0.909 ± 0.735
0.0GlnXaa: 0.0 ± 0.0
Arg
2.727ArgAla: 2.727 ± 1.394
0.909ArgCys: 0.909 ± 1.065
5.455ArgAsp: 5.455 ± 2.03
3.636ArgGlu: 3.636 ± 2.172
4.545ArgPhe: 4.545 ± 1.989
3.636ArgGly: 3.636 ± 1.412
1.818ArgHis: 1.818 ± 1.408
3.636ArgIle: 3.636 ± 1.367
3.636ArgLys: 3.636 ± 2.269
1.818ArgLeu: 1.818 ± 1.146
1.818ArgMet: 1.818 ± 1.471
0.0ArgAsn: 0.0 ± 0.0
7.273ArgPro: 7.273 ± 1.408
1.818ArgGln: 1.818 ± 1.659
7.273ArgArg: 7.273 ± 3.978
4.545ArgSer: 4.545 ± 1.919
2.727ArgThr: 2.727 ± 1.354
5.455ArgVal: 5.455 ± 2.845
0.0ArgTrp: 0.0 ± 0.0
0.909ArgTyr: 0.909 ± 1.065
0.0ArgXaa: 0.0 ± 0.0
Ser
5.455SerAla: 5.455 ± 2.517
0.0SerCys: 0.0 ± 0.0
2.727SerAsp: 2.727 ± 2.163
0.909SerGlu: 0.909 ± 0.67
2.727SerPhe: 2.727 ± 0.992
3.636SerGly: 3.636 ± 1.226
3.636SerHis: 3.636 ± 1.274
6.364SerIle: 6.364 ± 4.489
7.273SerLys: 7.273 ± 1.953
2.727SerLeu: 2.727 ± 1.223
1.818SerMet: 1.818 ± 1.555
4.545SerAsn: 4.545 ± 1.685
10.0SerPro: 10.0 ± 1.928
1.818SerGln: 1.818 ± 1.34
4.545SerArg: 4.545 ± 1.955
8.182SerSer: 8.182 ± 4.439
3.636SerThr: 3.636 ± 1.412
1.818SerVal: 1.818 ± 1.216
0.909SerTrp: 0.909 ± 0.735
2.727SerTyr: 2.727 ± 0.992
0.0SerXaa: 0.0 ± 0.0
Thr
1.818ThrAla: 1.818 ± 1.146
2.727ThrCys: 2.727 ± 2.517
1.818ThrAsp: 1.818 ± 1.14
2.727ThrGlu: 2.727 ± 1.459
1.818ThrPhe: 1.818 ± 1.14
2.727ThrGly: 2.727 ± 0.979
4.545ThrHis: 4.545 ± 1.894
3.636ThrIle: 3.636 ± 2.029
2.727ThrLys: 2.727 ± 1.431
2.727ThrLeu: 2.727 ± 1.015
0.909ThrMet: 0.909 ± 0.67
4.545ThrAsn: 4.545 ± 1.989
5.455ThrPro: 5.455 ± 1.985
0.909ThrGln: 0.909 ± 1.009
1.818ThrArg: 1.818 ± 1.146
3.636ThrSer: 3.636 ± 1.412
2.727ThrThr: 2.727 ± 2.517
5.455ThrVal: 5.455 ± 2.932
2.727ThrTrp: 2.727 ± 2.278
1.818ThrTyr: 1.818 ± 1.073
0.0ThrXaa: 0.0 ± 0.0
Val
0.909ValAla: 0.909 ± 1.148
0.909ValCys: 0.909 ± 0.67
1.818ValAsp: 1.818 ± 1.029
2.727ValGlu: 2.727 ± 3.195
4.545ValPhe: 4.545 ± 1.081
4.545ValGly: 4.545 ± 2.345
0.909ValHis: 0.909 ± 1.065
4.545ValIle: 4.545 ± 1.882
4.545ValLys: 4.545 ± 1.989
6.364ValLeu: 6.364 ± 2.115
0.909ValMet: 0.909 ± 0.735
1.818ValAsn: 1.818 ± 1.471
2.727ValPro: 2.727 ± 0.992
5.455ValGln: 5.455 ± 1.802
4.545ValArg: 4.545 ± 2.009
1.818ValSer: 1.818 ± 1.073
5.455ValThr: 5.455 ± 3.648
1.818ValVal: 1.818 ± 1.197
0.0ValTrp: 0.0 ± 0.0
5.455ValTyr: 5.455 ± 1.937
0.0ValXaa: 0.0 ± 0.0
Trp
1.818TrpAla: 1.818 ± 1.34
0.0TrpCys: 0.0 ± 0.0
1.818TrpAsp: 1.818 ± 1.375
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.909TrpIle: 0.909 ± 0.735
0.909TrpLys: 0.909 ± 1.148
0.0TrpLeu: 0.0 ± 0.0
0.909TrpMet: 0.909 ± 0.735
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.909TrpGln: 0.909 ± 0.67
2.727TrpArg: 2.727 ± 1.211
0.0TrpSer: 0.0 ± 0.0
1.818TrpThr: 1.818 ± 2.018
1.818TrpVal: 1.818 ± 0.755
0.0TrpTrp: 0.0 ± 0.0
0.909TrpTyr: 0.909 ± 0.67
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.727TyrAla: 2.727 ± 1.331
0.0TyrCys: 0.0 ± 0.0
2.727TyrAsp: 2.727 ± 1.678
0.909TyrGlu: 0.909 ± 0.735
4.545TyrPhe: 4.545 ± 1.382
0.909TyrGly: 0.909 ± 0.67
0.0TyrHis: 0.0 ± 0.0
0.0TyrIle: 0.0 ± 0.0
0.909TyrLys: 0.909 ± 0.67
5.455TyrLeu: 5.455 ± 1.594
2.727TyrMet: 2.727 ± 1.065
1.818TyrAsn: 1.818 ± 0.755
0.909TyrPro: 0.909 ± 0.67
0.909TyrGln: 0.909 ± 1.065
2.727TyrArg: 2.727 ± 2.206
3.636TyrSer: 3.636 ± 2.145
1.818TyrThr: 1.818 ± 1.146
1.818TyrVal: 1.818 ± 1.375
0.0TyrTrp: 0.0 ± 0.0
0.909TyrTyr: 0.909 ± 1.064
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1101 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski