Human papillomavirus type 41

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Nupapillomavirus; Nupapillomavirus 1

Average proteome isoelectric point is 7.29

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 11 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|Q84212|Q84212_HPV41 ORF X protein OS=Human papillomavirus type 41 OX=10589 GN=ORF X PE=4 SV=1
MM1 pKa = 7.91LARR4 pKa = 11.84QRR6 pKa = 11.84VKK8 pKa = 10.55RR9 pKa = 11.84ANPEE13 pKa = 3.72QLYY16 pKa = 7.9KK17 pKa = 9.76TCKK20 pKa = 9.13ATGGDD25 pKa = 4.25CPPDD29 pKa = 3.39VIKK32 pKa = 10.42RR33 pKa = 11.84YY34 pKa = 8.47EE35 pKa = 3.94QTTPADD41 pKa = 4.02SILKK45 pKa = 8.54YY46 pKa = 10.62GSVGVFFGGLGIGTGRR62 pKa = 11.84GGGGTVLGAGAVGGRR77 pKa = 11.84PSISSGAIGPRR88 pKa = 11.84DD89 pKa = 3.54ILPIEE94 pKa = 4.46SGGPSLAEE102 pKa = 4.58EE103 pKa = 4.38IPLLPMAPRR112 pKa = 11.84VPRR115 pKa = 11.84PTDD118 pKa = 3.24PFRR121 pKa = 11.84PSVLEE126 pKa = 3.72EE127 pKa = 3.88PFIIRR132 pKa = 11.84PPEE135 pKa = 4.03RR136 pKa = 11.84PNILHH141 pKa = 6.06EE142 pKa = 4.25QRR144 pKa = 11.84FPTDD148 pKa = 3.15AAPFDD153 pKa = 3.97NGNTEE158 pKa = 3.59ITTIPSQYY166 pKa = 9.93DD167 pKa = 3.38VSGGGVDD174 pKa = 3.21IQIIEE179 pKa = 4.4LPSVNDD185 pKa = 4.13PGPSVVTRR193 pKa = 11.84TQYY196 pKa = 11.34NNPTFEE202 pKa = 4.56VEE204 pKa = 4.0VSTDD208 pKa = 2.85ISGEE212 pKa = 4.05TSSTDD217 pKa = 3.49NIIVGAEE224 pKa = 3.86SGGTSVGDD232 pKa = 3.56NAEE235 pKa = 5.23LIPLLDD241 pKa = 3.53ISRR244 pKa = 11.84GDD246 pKa = 3.89TIDD249 pKa = 3.45TTILAPGEE257 pKa = 4.16EE258 pKa = 4.11EE259 pKa = 4.2TAFVTSTPEE268 pKa = 3.37RR269 pKa = 11.84VPIQEE274 pKa = 4.26RR275 pKa = 11.84LPIRR279 pKa = 11.84PYY281 pKa = 10.18GRR283 pKa = 11.84QYY285 pKa = 9.82QQVRR289 pKa = 11.84VTDD292 pKa = 4.05PEE294 pKa = 4.22FLDD297 pKa = 3.78SAAVLVSLEE306 pKa = 4.14NPVFDD311 pKa = 5.69ADD313 pKa = 3.3ITLTFEE319 pKa = 6.62DD320 pKa = 5.33DD321 pKa = 3.35LQQALRR327 pKa = 11.84SDD329 pKa = 3.33TDD331 pKa = 3.38LRR333 pKa = 11.84DD334 pKa = 3.33VRR336 pKa = 11.84RR337 pKa = 11.84LSRR340 pKa = 11.84PYY342 pKa = 8.82YY343 pKa = 9.08QRR345 pKa = 11.84RR346 pKa = 11.84TTGLRR351 pKa = 11.84VSRR354 pKa = 11.84LGQRR358 pKa = 11.84RR359 pKa = 11.84GTISTRR365 pKa = 11.84SGVQVGSAAHH375 pKa = 6.6FFQDD379 pKa = 4.14ISPIGQAIEE388 pKa = 4.66PIDD391 pKa = 5.0AIEE394 pKa = 4.52LDD396 pKa = 3.81VLGEE400 pKa = 3.94QSGEE404 pKa = 3.98GTIVRR409 pKa = 11.84GDD411 pKa = 3.61PTPSIEE417 pKa = 4.35QDD419 pKa = 2.75IGLTALGDD427 pKa = 3.94NIEE430 pKa = 4.67NEE432 pKa = 4.11LQEE435 pKa = 5.33IDD437 pKa = 5.17LLTADD442 pKa = 4.51GEE444 pKa = 4.29EE445 pKa = 4.23DD446 pKa = 3.53QEE448 pKa = 4.88GRR450 pKa = 11.84DD451 pKa = 3.69LQLVFSTGNDD461 pKa = 3.09EE462 pKa = 4.65VVDD465 pKa = 3.51IMTIPIRR472 pKa = 11.84AGGDD476 pKa = 3.22DD477 pKa = 3.88RR478 pKa = 11.84PSVFIFSDD486 pKa = 3.72DD487 pKa = 3.49GTHH490 pKa = 6.18IVYY493 pKa = 7.71PTSTTATTPLVPAQPSDD510 pKa = 3.43VPYY513 pKa = 10.47IVVDD517 pKa = 4.9LYY519 pKa = 11.18SGSMDD524 pKa = 3.9YY525 pKa = 10.7DD526 pKa = 3.35IHH528 pKa = 6.94PSLLRR533 pKa = 11.84RR534 pKa = 11.84KK535 pKa = 8.4RR536 pKa = 11.84KK537 pKa = 8.73KK538 pKa = 9.56RR539 pKa = 11.84KK540 pKa = 8.97RR541 pKa = 11.84VYY543 pKa = 10.53FSDD546 pKa = 3.09GRR548 pKa = 11.84VASRR552 pKa = 11.84PKK554 pKa = 10.56

Molecular weight: 59.97 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|Q84214|Q84214_HPV41 ORF Z protein OS=Human papillomavirus type 41 OX=10589 GN=ORF Z PE=4 SV=1
MM1 pKa = 7.64LPLTVCLLLDD11 pKa = 3.19IHH13 pKa = 6.02FTILLMRR20 pKa = 11.84MAKK23 pKa = 9.38RR24 pKa = 11.84WSLKK28 pKa = 10.27FPLISSGPSVSVSQIPIPLHH48 pKa = 5.63FVISPFLTLTRR59 pKa = 11.84SVWSGVFVGLRR70 pKa = 11.84FLGDD74 pKa = 3.59SPP76 pKa = 4.73

Molecular weight: 8.5 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

11

0

11

2765

72

614

251.4

28.38

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.004 ± 0.263

2.061 ± 0.64

6.004 ± 0.821

6.221 ± 0.683

4.014 ± 0.619

6.727 ± 0.868

2.242 ± 0.474

5.461 ± 0.677

4.34 ± 0.678

9.042 ± 0.739

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.17 ± 0.537

4.087 ± 0.701

5.497 ± 0.834

4.304 ± 0.429

7.74 ± 0.789

7.414 ± 0.338

6.293 ± 0.574

5.931 ± 0.523

1.193 ± 0.338

3.255 ± 0.372
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski