Amino acid dipepetide frequency for Beihai picorna-like virus 21

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.596AlaAla: 3.596 ± 2.397
1.199AlaCys: 1.199 ± 0.705
2.397AlaAsp: 2.397 ± 1.168
5.593AlaGlu: 5.593 ± 0.577
1.998AlaPhe: 1.998 ± 1.403
3.995AlaGly: 3.995 ± 0.873
1.998AlaHis: 1.998 ± 0.53
5.993AlaIle: 5.993 ± 0.946
3.596AlaLys: 3.596 ± 0.181
3.596AlaLeu: 3.596 ± 0.826
1.998AlaMet: 1.998 ± 0.348
3.596AlaAsn: 3.596 ± 0.181
3.196AlaPro: 3.196 ± 1.343
0.799AlaGln: 0.799 ± 0.819
1.998AlaArg: 1.998 ± 0.114
5.593AlaSer: 5.593 ± 1.222
4.794AlaThr: 4.794 ± 0.403
5.593AlaVal: 5.593 ± 1.222
0.4AlaTrp: 0.4 ± 0.409
2.397AlaTyr: 2.397 ± 0.765
0.0AlaXaa: 0.0 ± 0.0
Cys
2.397CysAla: 2.397 ± 0.765
0.4CysCys: 0.4 ± 0.235
0.799CysAsp: 0.799 ± 0.47
0.4CysGlu: 0.4 ± 0.235
1.199CysPhe: 1.199 ± 0.705
1.199CysGly: 1.199 ± 0.705
0.799CysHis: 0.799 ± 0.47
0.0CysIle: 0.0 ± 0.0
1.199CysLys: 1.199 ± 0.705
0.4CysLeu: 0.4 ± 0.235
0.4CysMet: 0.4 ± 0.235
1.199CysAsn: 1.199 ± 0.06
1.199CysPro: 1.199 ± 0.06
0.4CysGln: 0.4 ± 0.409
2.397CysArg: 2.397 ± 0.765
1.998CysSer: 1.998 ± 0.53
0.799CysThr: 0.799 ± 0.47
0.4CysVal: 0.4 ± 0.235
0.799CysTrp: 0.799 ± 0.47
1.199CysTyr: 1.199 ± 0.705
0.0CysXaa: 0.0 ± 0.0
Asp
3.596AspAla: 3.596 ± 1.108
0.0AspCys: 0.0 ± 0.0
4.794AspAsp: 4.794 ± 1.047
1.998AspGlu: 1.998 ± 0.53
3.596AspPhe: 3.596 ± 1.108
3.596AspGly: 3.596 ± 0.181
0.799AspHis: 0.799 ± 0.47
3.995AspIle: 3.995 ± 0.228
4.794AspLys: 4.794 ± 1.53
3.196AspLeu: 3.196 ± 0.054
1.598AspMet: 1.598 ± 0.295
2.397AspAsn: 2.397 ± 1.168
3.995AspPro: 3.995 ± 2.806
2.397AspGln: 2.397 ± 0.121
2.397AspArg: 2.397 ± 1.41
5.593AspSer: 5.593 ± 2.0
1.199AspThr: 1.199 ± 1.228
1.598AspVal: 1.598 ± 0.94
1.199AspTrp: 1.199 ± 0.06
1.598AspTyr: 1.598 ± 0.295
0.0AspXaa: 0.0 ± 0.0
Glu
3.995GluAla: 3.995 ± 0.228
0.799GluCys: 0.799 ± 0.175
2.797GluAsp: 2.797 ± 0.289
2.797GluGlu: 2.797 ± 0.289
3.196GluPhe: 3.196 ± 0.591
4.794GluGly: 4.794 ± 1.53
1.998GluHis: 1.998 ± 0.53
4.794GluIle: 4.794 ± 0.886
2.397GluLys: 2.397 ± 1.41
5.194GluLeu: 5.194 ± 0.168
0.4GluMet: 0.4 ± 0.235
3.196GluAsn: 3.196 ± 0.591
3.596GluPro: 3.596 ± 0.463
2.397GluGln: 2.397 ± 0.765
3.596GluArg: 3.596 ± 0.463
2.397GluSer: 2.397 ± 1.168
1.598GluThr: 1.598 ± 0.349
3.596GluVal: 3.596 ± 0.463
1.199GluTrp: 1.199 ± 0.705
2.397GluTyr: 2.397 ± 0.765
0.0GluXaa: 0.0 ± 0.0
Phe
2.797PheAla: 2.797 ± 0.933
0.799PheCys: 0.799 ± 0.47
1.998PheAsp: 1.998 ± 0.759
2.397PheGlu: 2.397 ± 0.524
1.598PhePhe: 1.598 ± 0.349
3.995PheGly: 3.995 ± 1.06
0.799PheHis: 0.799 ± 0.819
1.998PheIle: 1.998 ± 0.53
4.395PheLys: 4.395 ± 1.295
7.191PheLeu: 7.191 ± 0.362
0.799PheMet: 0.799 ± 0.175
1.998PheAsn: 1.998 ± 0.114
2.397PhePro: 2.397 ± 1.168
2.397PheGln: 2.397 ± 1.168
1.598PheArg: 1.598 ± 0.349
3.196PheSer: 3.196 ± 0.054
1.998PheThr: 1.998 ± 0.759
2.797PheVal: 2.797 ± 0.933
0.0PheTrp: 0.0 ± 0.0
3.196PheTyr: 3.196 ± 0.054
0.0PheXaa: 0.0 ± 0.0
Gly
5.993GlyAla: 5.993 ± 1.631
1.598GlyCys: 1.598 ± 0.94
4.794GlyAsp: 4.794 ± 0.886
4.395GlyGlu: 4.395 ± 0.007
2.797GlyPhe: 2.797 ± 0.933
3.196GlyGly: 3.196 ± 1.235
0.0GlyHis: 0.0 ± 0.0
3.995GlyIle: 3.995 ± 1.705
2.797GlyLys: 2.797 ± 0.356
5.993GlyLeu: 5.993 ± 0.343
2.397GlyMet: 2.397 ± 0.121
3.596GlyAsn: 3.596 ± 0.463
1.998GlyPro: 1.998 ± 0.759
3.596GlyGln: 3.596 ± 0.181
1.998GlyArg: 1.998 ± 1.403
4.794GlySer: 4.794 ± 0.242
5.993GlyThr: 5.993 ± 1.631
3.995GlyVal: 3.995 ± 0.416
0.799GlyTrp: 0.799 ± 0.175
3.196GlyTyr: 3.196 ± 1.343
0.0GlyXaa: 0.0 ± 0.0
His
0.799HisAla: 0.799 ± 0.819
0.799HisCys: 0.799 ± 0.175
0.4HisAsp: 0.4 ± 0.409
0.799HisGlu: 0.799 ± 0.47
0.799HisPhe: 0.799 ± 0.175
1.998HisGly: 1.998 ± 0.114
0.4HisHis: 0.4 ± 0.235
1.199HisIle: 1.199 ± 0.705
1.998HisLys: 1.998 ± 0.759
2.397HisLeu: 2.397 ± 1.41
0.799HisMet: 0.799 ± 0.47
0.0HisAsn: 0.0 ± 0.0
0.799HisPro: 0.799 ± 0.47
0.4HisGln: 0.4 ± 0.409
0.4HisArg: 0.4 ± 0.235
0.799HisSer: 0.799 ± 0.175
0.4HisThr: 0.4 ± 0.235
1.598HisVal: 1.598 ± 0.295
0.4HisTrp: 0.4 ± 0.409
1.199HisTyr: 1.199 ± 0.705
0.0HisXaa: 0.0 ± 0.0
Ile
5.194IleAla: 5.194 ± 0.812
1.199IleCys: 1.199 ± 0.705
5.593IleAsp: 5.593 ± 0.711
4.794IleGlu: 4.794 ± 0.242
2.797IlePhe: 2.797 ± 0.356
3.596IleGly: 3.596 ± 1.108
0.0IleHis: 0.0 ± 0.0
1.998IleIle: 1.998 ± 0.114
2.797IleLys: 2.797 ± 1.645
2.397IleLeu: 2.397 ± 0.765
2.397IleMet: 2.397 ± 0.765
5.194IleAsn: 5.194 ± 1.457
2.397IlePro: 2.397 ± 0.765
1.998IleGln: 1.998 ± 0.53
3.196IleArg: 3.196 ± 0.054
4.395IleSer: 4.395 ± 0.638
3.995IleThr: 3.995 ± 0.416
4.395IleVal: 4.395 ± 0.007
0.4IleTrp: 0.4 ± 0.235
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
3.596LysAla: 3.596 ± 0.463
1.199LysCys: 1.199 ± 0.705
3.196LysAsp: 3.196 ± 1.235
2.397LysGlu: 2.397 ± 1.41
1.598LysPhe: 1.598 ± 0.295
3.995LysGly: 3.995 ± 0.416
0.799LysHis: 0.799 ± 0.819
3.196LysIle: 3.196 ± 0.054
2.797LysLys: 2.797 ± 1.645
6.792LysLeu: 6.792 ± 1.416
1.598LysMet: 1.598 ± 0.94
2.797LysAsn: 2.797 ± 0.356
2.797LysPro: 2.797 ± 0.356
2.797LysGln: 2.797 ± 0.356
2.797LysArg: 2.797 ± 0.356
3.596LysSer: 3.596 ± 2.114
4.395LysThr: 4.395 ± 1.295
3.596LysVal: 3.596 ± 0.826
0.799LysTrp: 0.799 ± 0.47
1.998LysTyr: 1.998 ± 0.53
0.0LysXaa: 0.0 ± 0.0
Leu
2.797LeuAla: 2.797 ± 1.0
3.196LeuCys: 3.196 ± 1.235
5.194LeuAsp: 5.194 ± 0.168
3.995LeuGlu: 3.995 ± 1.06
2.797LeuPhe: 2.797 ± 1.0
3.995LeuGly: 3.995 ± 0.416
1.998LeuHis: 1.998 ± 0.114
3.995LeuIle: 3.995 ± 1.705
5.993LeuLys: 5.993 ± 0.946
7.591LeuLeu: 7.591 ± 0.597
3.196LeuMet: 3.196 ± 1.127
1.998LeuAsn: 1.998 ± 0.53
4.794LeuPro: 4.794 ± 0.242
3.196LeuGln: 3.196 ± 0.054
5.194LeuArg: 5.194 ± 0.476
5.993LeuSer: 5.993 ± 1.631
8.789LeuThr: 8.789 ± 0.013
7.591LeuVal: 7.591 ± 1.886
0.799LeuTrp: 0.799 ± 0.819
3.596LeuTyr: 3.596 ± 1.752
0.0LeuXaa: 0.0 ± 0.0
Met
2.397MetAla: 2.397 ± 0.765
1.598MetCys: 1.598 ± 0.94
1.598MetAsp: 1.598 ± 0.295
1.598MetGlu: 1.598 ± 0.295
0.799MetPhe: 0.799 ± 0.175
1.998MetGly: 1.998 ± 0.759
0.4MetHis: 0.4 ± 0.235
1.598MetIle: 1.598 ± 0.295
2.797MetLys: 2.797 ± 0.356
1.598MetLeu: 1.598 ± 0.94
1.199MetMet: 1.199 ± 0.705
1.598MetAsn: 1.598 ± 0.349
1.598MetPro: 1.598 ± 0.349
0.799MetGln: 0.799 ± 0.175
0.4MetArg: 0.4 ± 0.409
1.998MetSer: 1.998 ± 0.53
2.397MetThr: 2.397 ± 1.41
0.799MetVal: 0.799 ± 0.47
0.4MetTrp: 0.4 ± 0.235
1.598MetTyr: 1.598 ± 0.994
0.0MetXaa: 0.0 ± 0.0
Asn
1.998AsnAla: 1.998 ± 0.53
0.799AsnCys: 0.799 ± 0.47
1.598AsnAsp: 1.598 ± 0.994
2.397AsnGlu: 2.397 ± 1.168
3.596AsnPhe: 3.596 ± 1.108
4.395AsnGly: 4.395 ± 0.638
0.799AsnHis: 0.799 ± 0.175
3.596AsnIle: 3.596 ± 0.463
3.196AsnLys: 3.196 ± 0.591
6.792AsnLeu: 6.792 ± 0.517
1.598AsnMet: 1.598 ± 0.295
2.397AsnAsn: 2.397 ± 0.121
2.797AsnPro: 2.797 ± 0.289
0.799AsnGln: 0.799 ± 0.47
1.598AsnArg: 1.598 ± 0.994
2.397AsnSer: 2.397 ± 1.168
3.196AsnThr: 3.196 ± 1.343
5.993AsnVal: 5.993 ± 0.343
1.998AsnTrp: 1.998 ± 0.53
1.598AsnTyr: 1.598 ± 0.994
0.0AsnXaa: 0.0 ± 0.0
Pro
1.598ProAla: 1.598 ± 0.994
0.4ProCys: 0.4 ± 0.235
1.598ProAsp: 1.598 ± 0.349
3.995ProGlu: 3.995 ± 0.416
3.995ProPhe: 3.995 ± 1.517
2.797ProGly: 2.797 ± 1.578
1.998ProHis: 1.998 ± 0.114
1.998ProIle: 1.998 ± 0.53
2.397ProLys: 2.397 ± 0.765
5.593ProLeu: 5.593 ± 0.711
1.998ProMet: 1.998 ± 1.403
1.998ProAsn: 1.998 ± 1.403
1.598ProPro: 1.598 ± 0.349
1.998ProGln: 1.998 ± 1.403
1.199ProArg: 1.199 ± 1.228
3.196ProSer: 3.196 ± 0.591
3.196ProThr: 3.196 ± 0.698
1.598ProVal: 1.598 ± 0.349
0.4ProTrp: 0.4 ± 0.409
1.598ProTyr: 1.598 ± 0.994
0.0ProXaa: 0.0 ± 0.0
Gln
1.598GlnAla: 1.598 ± 0.349
1.998GlnCys: 1.998 ± 1.175
2.397GlnAsp: 2.397 ± 0.765
2.397GlnGlu: 2.397 ± 0.121
3.196GlnPhe: 3.196 ± 0.591
0.4GlnGly: 0.4 ± 0.235
0.4GlnHis: 0.4 ± 0.235
1.598GlnIle: 1.598 ± 1.638
1.598GlnLys: 1.598 ± 0.349
2.797GlnLeu: 2.797 ± 0.356
0.799GlnMet: 0.799 ± 0.47
3.196GlnAsn: 3.196 ± 1.987
1.598GlnPro: 1.598 ± 0.349
3.196GlnGln: 3.196 ± 0.698
2.397GlnArg: 2.397 ± 0.765
4.794GlnSer: 4.794 ± 2.336
0.799GlnThr: 0.799 ± 0.47
1.998GlnVal: 1.998 ± 0.53
0.4GlnTrp: 0.4 ± 0.409
1.199GlnTyr: 1.199 ± 0.705
0.0GlnXaa: 0.0 ± 0.0
Arg
5.194ArgAla: 5.194 ± 0.168
1.199ArgCys: 1.199 ± 0.705
2.397ArgAsp: 2.397 ± 0.765
2.797ArgGlu: 2.797 ± 0.289
1.998ArgPhe: 1.998 ± 0.114
3.596ArgGly: 3.596 ± 1.108
0.0ArgHis: 0.0 ± 0.0
3.596ArgIle: 3.596 ± 0.463
3.196ArgLys: 3.196 ± 0.591
2.397ArgLeu: 2.397 ± 0.121
1.998ArgMet: 1.998 ± 1.175
2.397ArgAsn: 2.397 ± 0.765
2.397ArgPro: 2.397 ± 0.524
0.4ArgGln: 0.4 ± 0.235
5.194ArgArg: 5.194 ± 1.121
2.797ArgSer: 2.797 ± 0.356
2.797ArgThr: 2.797 ± 0.289
2.797ArgVal: 2.797 ± 0.933
0.799ArgTrp: 0.799 ± 0.175
1.199ArgTyr: 1.199 ± 0.06
0.0ArgXaa: 0.0 ± 0.0
Ser
4.395SerAla: 4.395 ± 0.638
0.799SerCys: 0.799 ± 0.47
3.995SerAsp: 3.995 ± 0.416
5.593SerGlu: 5.593 ± 0.067
2.797SerPhe: 2.797 ± 0.933
6.392SerGly: 6.392 ± 1.396
1.598SerHis: 1.598 ± 0.94
5.194SerIle: 5.194 ± 0.168
3.596SerLys: 3.596 ± 0.181
7.191SerLeu: 7.191 ± 2.296
1.998SerMet: 1.998 ± 1.403
2.397SerAsn: 2.397 ± 0.524
2.797SerPro: 2.797 ± 1.578
4.794SerGln: 4.794 ± 0.886
1.998SerArg: 1.998 ± 0.114
4.794SerSer: 4.794 ± 0.242
1.199SerThr: 1.199 ± 0.705
3.995SerVal: 3.995 ± 0.873
1.199SerTrp: 1.199 ± 0.705
3.995SerTyr: 3.995 ± 0.228
0.0SerXaa: 0.0 ± 0.0
Thr
4.395ThrAla: 4.395 ± 1.282
0.4ThrCys: 0.4 ± 0.235
2.397ThrAsp: 2.397 ± 0.121
2.397ThrGlu: 2.397 ± 0.765
3.196ThrPhe: 3.196 ± 0.054
5.593ThrGly: 5.593 ± 1.866
1.598ThrHis: 1.598 ± 0.295
4.395ThrIle: 4.395 ± 1.282
1.998ThrLys: 1.998 ± 1.175
6.392ThrLeu: 6.392 ± 1.396
1.598ThrMet: 1.598 ± 0.94
5.194ThrAsn: 5.194 ± 1.457
2.397ThrPro: 2.397 ± 0.121
2.397ThrGln: 2.397 ± 0.121
1.998ThrArg: 1.998 ± 0.114
3.995ThrSer: 3.995 ± 0.873
7.191ThrThr: 7.191 ± 2.86
3.995ThrVal: 3.995 ± 0.228
0.0ThrTrp: 0.0 ± 0.0
2.797ThrTyr: 2.797 ± 1.0
0.0ThrXaa: 0.0 ± 0.0
Val
4.794ValAla: 4.794 ± 0.242
0.4ValCys: 0.4 ± 0.409
3.196ValAsp: 3.196 ± 1.343
3.995ValGlu: 3.995 ± 1.06
2.397ValPhe: 2.397 ± 1.168
2.797ValGly: 2.797 ± 1.0
0.4ValHis: 0.4 ± 0.235
3.596ValIle: 3.596 ± 0.463
2.397ValLys: 2.397 ± 0.765
3.995ValLeu: 3.995 ± 0.416
1.199ValMet: 1.199 ± 0.06
5.194ValAsn: 5.194 ± 0.168
1.598ValPro: 1.598 ± 1.638
2.397ValGln: 2.397 ± 0.121
4.794ValArg: 4.794 ± 1.53
3.995ValSer: 3.995 ± 0.416
5.993ValThr: 5.993 ± 1.631
2.797ValVal: 2.797 ± 1.578
1.199ValTrp: 1.199 ± 0.705
4.395ValTyr: 4.395 ± 0.007
0.0ValXaa: 0.0 ± 0.0
Trp
0.799TrpAla: 0.799 ± 0.175
0.0TrpCys: 0.0 ± 0.0
0.4TrpAsp: 0.4 ± 0.235
0.799TrpGlu: 0.799 ± 0.47
1.598TrpPhe: 1.598 ± 0.94
1.199TrpGly: 1.199 ± 0.584
0.4TrpHis: 0.4 ± 0.235
0.799TrpIle: 0.799 ± 0.175
0.799TrpLys: 0.799 ± 0.175
0.4TrpLeu: 0.4 ± 0.235
0.0TrpMet: 0.0 ± 0.0
0.799TrpAsn: 0.799 ± 0.175
0.0TrpPro: 0.0 ± 0.0
0.4TrpGln: 0.4 ± 0.235
2.397TrpArg: 2.397 ± 0.765
0.799TrpSer: 0.799 ± 0.175
1.199TrpThr: 1.199 ± 0.584
0.799TrpVal: 0.799 ± 0.175
0.0TrpTrp: 0.0 ± 0.0
0.4TrpTyr: 0.4 ± 0.235
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.797TyrAla: 2.797 ± 0.356
0.799TyrCys: 0.799 ± 0.819
2.797TyrAsp: 2.797 ± 0.289
1.598TyrGlu: 1.598 ± 0.349
2.397TyrPhe: 2.397 ± 0.121
4.395TyrGly: 4.395 ± 0.651
1.199TyrHis: 1.199 ± 0.584
1.199TyrIle: 1.199 ± 0.705
1.998TyrLys: 1.998 ± 0.53
4.794TyrLeu: 4.794 ± 0.403
0.799TyrMet: 0.799 ± 0.175
2.397TyrAsn: 2.397 ± 0.524
1.199TyrPro: 1.199 ± 0.06
1.199TyrGln: 1.199 ± 0.584
1.598TyrArg: 1.598 ± 0.349
3.596TyrSer: 3.596 ± 1.47
2.397TyrThr: 2.397 ± 0.121
1.598TyrVal: 1.598 ± 0.349
0.799TyrTrp: 0.799 ± 0.175
1.998TyrTyr: 1.998 ± 0.114
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2504 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski