Methanosphaera sp. BMS
Taxonomy: cellular organisms; Archaea; Euryarchaeota; Methanomada group; Methanobacteria; Methanobacteriales; Methanobacteriaceae; Methanosphaera; unclassified Methanosphaera
Average proteome isoelectric point is 5.77
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Virtual 2D-PAGE plot for 2101 proteins (isoelectric point calculated using IPC2_protein)
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Summary statistics related to proteome-wise predictions
Protein with the lowest isoelectric point:
>tr|A0A2Z4L7J4|A0A2Z4L7J4_9EURY ATPase OS=Methanosphaera sp. BMS OX=1789762 GN=AW729_03175 PE=4 SV=1
MM1 pKa = 7.28NKK3 pKa = 10.02KK4 pKa = 9.29NVKK7 pKa = 9.49IFTFISLIFVALLIIGGVSAAVDD30 pKa = 3.91DD31 pKa = 4.88SPAATVDD38 pKa = 3.84DD39 pKa = 4.2DD40 pKa = 5.0TITADD45 pKa = 3.63AVTASSDD52 pKa = 3.51VQSNNEE58 pKa = 4.07IITNEE63 pKa = 4.06AIKK66 pKa = 10.31EE67 pKa = 4.0EE68 pKa = 4.39RR69 pKa = 11.84SVKK72 pKa = 10.05GAQQQLPANDD82 pKa = 3.47YY83 pKa = 11.15SEE85 pKa = 5.8LKK87 pKa = 9.53TAVNTAKK94 pKa = 9.97MDD96 pKa = 4.65DD97 pKa = 3.94NDD99 pKa = 3.86ANSYY103 pKa = 10.23VISLSQSGTYY113 pKa = 9.88EE114 pKa = 3.26VDD116 pKa = 4.94APIKK120 pKa = 7.27WTSMGNPTLTIEE132 pKa = 4.56GNGATITGNSNQFFTINSGRR152 pKa = 11.84TLIINNIIIDD162 pKa = 4.04GTSADD167 pKa = 4.57DD168 pKa = 4.9GGAINNNGTITLTNSIIKK186 pKa = 10.46NSIATNGGAIYY197 pKa = 10.46SIGTVNLEE205 pKa = 3.96NVTLQANEE213 pKa = 3.8ATKK216 pKa = 10.57KK217 pKa = 10.67GGAIYY222 pKa = 9.07STGTVNAKK230 pKa = 10.1NVTFKK235 pKa = 11.47DD236 pKa = 3.42NLVTDD241 pKa = 5.35GSHH244 pKa = 6.96GDD246 pKa = 3.46NDD248 pKa = 4.16GGAGIYY254 pKa = 7.0TTGAIYY260 pKa = 10.32IEE262 pKa = 5.14DD263 pKa = 3.71STFDD267 pKa = 3.87SNIGQYY273 pKa = 10.22TDD275 pKa = 3.51TSSSSNGADD284 pKa = 2.83GGAIRR289 pKa = 11.84VKK291 pKa = 10.91DD292 pKa = 4.37SISDD296 pKa = 3.67MIITNTTFTNNKK308 pKa = 8.08GRR310 pKa = 11.84HH311 pKa = 5.09GGALLICDD319 pKa = 4.42DD320 pKa = 4.14EE321 pKa = 4.83GRR323 pKa = 11.84NQGIKK328 pKa = 10.2KK329 pKa = 8.24ITGSTFTGNQAIYY342 pKa = 9.96GGAIEE347 pKa = 5.0VYY349 pKa = 9.93NDD351 pKa = 4.53LIIEE355 pKa = 4.29DD356 pKa = 4.24SVFEE360 pKa = 4.26EE361 pKa = 4.49NSVKK365 pKa = 10.87GIGSGNRR372 pKa = 11.84NPLGGAICVNDD383 pKa = 4.22LVDD386 pKa = 3.94NGAPGSLSVKK396 pKa = 9.11NTTFEE401 pKa = 4.49KK402 pKa = 9.8NTASTTFEE410 pKa = 4.38EE411 pKa = 5.3GTTNYY416 pKa = 10.51GSGGAIYY423 pKa = 10.56NSGPGATIEE432 pKa = 3.97NCTFTEE438 pKa = 4.02NEE440 pKa = 4.42AYY442 pKa = 10.24DD443 pKa = 3.65GGAIEE448 pKa = 6.02DD449 pKa = 4.15EE450 pKa = 4.58ATSSTIKK457 pKa = 10.87DD458 pKa = 3.47SVFEE462 pKa = 4.01QNTAVEE468 pKa = 4.22TGGAIFTINNGTGTTANINNCTFTEE493 pKa = 4.17NSANNGGAIATIGNTTMNIDD513 pKa = 3.48EE514 pKa = 5.14CSFDD518 pKa = 4.12QNTATSNGGAYY529 pKa = 10.18YY530 pKa = 9.0STWDD534 pKa = 3.46TYY536 pKa = 11.71NLPRR540 pKa = 11.84LFKK543 pKa = 10.36HH544 pKa = 6.85ASITNSNFTDD554 pKa = 3.47NTANDD559 pKa = 3.44YY560 pKa = 10.18PAIYY564 pKa = 9.79DD565 pKa = 3.93SNSGPFNGGSSSTVIDD581 pKa = 3.27NCKK584 pKa = 10.47FEE586 pKa = 6.13DD587 pKa = 3.87NVATSASGSTIYY599 pKa = 10.13TRR601 pKa = 11.84YY602 pKa = 10.52ASTSITNSNISDD614 pKa = 3.72TNNRR618 pKa = 11.84AIASVWNNGVANMEE632 pKa = 3.97NDD634 pKa = 3.14IVNGLDD640 pKa = 3.26VDD642 pKa = 4.38SMNNGNLEE650 pKa = 4.25VSVSNYY656 pKa = 10.55AEE658 pKa = 3.96LVAITDD664 pKa = 3.74VLNNQYY670 pKa = 11.17NSADD674 pKa = 3.24PVYY677 pKa = 10.91INFTGDD683 pKa = 2.93AVYY686 pKa = 10.55TEE688 pKa = 4.69TEE690 pKa = 4.24PIAYY694 pKa = 9.55EE695 pKa = 4.27NINCPVTFIGNGKK708 pKa = 8.1TIDD711 pKa = 3.6ANGMQFVTIGEE722 pKa = 4.5GKK724 pKa = 10.26SLTIRR729 pKa = 11.84NLTIKK734 pKa = 10.3NAQADD739 pKa = 3.58NGAAVLNYY747 pKa = 10.61GSLTVNSDD755 pKa = 3.67SVFEE759 pKa = 5.12DD760 pKa = 3.53NSALYY765 pKa = 10.41NGGAIYY771 pKa = 9.06STGNLTITKK780 pKa = 9.64TNFTNNEE787 pKa = 3.92VTTHH791 pKa = 5.65QGAGQKK797 pKa = 10.39DD798 pKa = 4.0YY799 pKa = 11.56GGGAICSLGKK809 pKa = 10.71LSVQTSNFVEE819 pKa = 4.22NTAAHH824 pKa = 6.68NDD826 pKa = 3.52VEE828 pKa = 4.58PNGDD832 pKa = 3.55GGVAGAILVLNTTQEE847 pKa = 4.06VSITTSNFTKK857 pKa = 10.55NDD859 pKa = 3.14GRR861 pKa = 11.84HH862 pKa = 5.69GGAITINNNDD872 pKa = 3.5KK873 pKa = 11.28EE874 pKa = 4.39NTKK877 pKa = 10.52KK878 pKa = 9.35VTINKK883 pKa = 9.66NNFVEE888 pKa = 4.35NTALYY893 pKa = 9.95GAAIDD898 pKa = 4.61TYY900 pKa = 10.55QQANITNNNFTKK912 pKa = 9.96NTVTGQGSGDD922 pKa = 3.82RR923 pKa = 11.84VPMGAAICANQGDD936 pKa = 4.41YY937 pKa = 10.88EE938 pKa = 4.36YY939 pKa = 10.9TLTLINNTFKK949 pKa = 11.12EE950 pKa = 4.47NEE952 pKa = 4.1AQDD955 pKa = 3.91NGCGGVMLTMPDD967 pKa = 3.34STIVSSNNVYY977 pKa = 10.57EE978 pKa = 4.08NNKK981 pKa = 10.54AYY983 pKa = 8.36DD984 pKa = 3.52TGVACIQGSATFTNDD999 pKa = 2.54TFTGNEE1005 pKa = 3.92GTGYY1009 pKa = 9.31TGVFTQAGDD1018 pKa = 3.34EE1019 pKa = 4.12LTITGCTFEE1028 pKa = 4.74NNEE1031 pKa = 3.85GNGYY1035 pKa = 10.8GDD1037 pKa = 2.79IAYY1040 pKa = 9.51AYY1042 pKa = 8.95EE1043 pKa = 4.76GYY1045 pKa = 10.33EE1046 pKa = 3.93VTITDD1051 pKa = 3.39STIITEE1057 pKa = 4.27NEE1059 pKa = 3.9FGDD1062 pKa = 4.36LMSPANSDD1070 pKa = 3.53DD1071 pKa = 4.28FEE1073 pKa = 4.42GTNVKK1078 pKa = 10.43VNGVTFAYY1086 pKa = 9.76TDD1088 pKa = 3.72FKK1090 pKa = 11.55DD1091 pKa = 4.09PIVFDD1096 pKa = 3.5VADD1099 pKa = 3.77YY1100 pKa = 11.31QEE1102 pKa = 5.3LVDD1105 pKa = 5.5LVALIKK1111 pKa = 10.51SEE1113 pKa = 3.97QIAFNVVANLTGTTYY1128 pKa = 10.88TEE1130 pKa = 4.18TEE1132 pKa = 4.74PIVLDD1137 pKa = 3.39DD1138 pKa = 4.03TFPAEE1143 pKa = 4.02SFTIEE1148 pKa = 4.35GNGKK1152 pKa = 8.21TIDD1155 pKa = 3.44ASGMQFLTVGEE1166 pKa = 4.41GQTVTINNLTVANAQADD1183 pKa = 3.65NGAAIINHH1191 pKa = 6.63GDD1193 pKa = 3.34LTINDD1198 pKa = 4.13AVFEE1202 pKa = 4.94DD1203 pKa = 3.85NQALYY1208 pKa = 10.48RR1209 pKa = 11.84GGAILTDD1216 pKa = 3.38GTLTVNRR1223 pKa = 11.84TKK1225 pKa = 10.02FTNNQVTTHH1234 pKa = 5.85QGAGSKK1240 pKa = 10.39DD1241 pKa = 3.56YY1242 pKa = 11.54GGGAICAFGEE1252 pKa = 4.29LTVDD1256 pKa = 3.52EE1257 pKa = 5.16SVFTANVAAHH1267 pKa = 6.75NDD1269 pKa = 3.5VEE1271 pKa = 4.5PNGDD1275 pKa = 3.55GGVAGAILILNNSEE1289 pKa = 5.54DD1290 pKa = 3.49ITITNSNFTQNTGRR1304 pKa = 11.84HH1305 pKa = 5.4GGAITINDD1313 pKa = 3.63NLHH1316 pKa = 6.57RR1317 pKa = 11.84DD1318 pKa = 3.75EE1319 pKa = 4.51GTVTIDD1325 pKa = 4.97SNNFDD1330 pKa = 4.61NNDD1333 pKa = 3.6ALYY1336 pKa = 10.46GAAIDD1341 pKa = 4.27TFHH1344 pKa = 7.26SAIITNNNFTNNWIDD1359 pKa = 3.68GQGSGDD1365 pKa = 3.96RR1366 pKa = 11.84VPMGAAICINNGGDD1380 pKa = 3.54PDD1382 pKa = 3.85YY1383 pKa = 11.24TITLEE1388 pKa = 4.0NNIFRR1393 pKa = 11.84GNEE1396 pKa = 3.79AKK1398 pKa = 10.83DD1399 pKa = 3.51NGCAGAVFTMPDD1411 pKa = 3.16TTLNSANNVYY1421 pKa = 10.16EE1422 pKa = 4.0NNKK1425 pKa = 10.54AYY1427 pKa = 8.35DD1428 pKa = 3.6TGVATIQGIATFTNDD1443 pKa = 2.92TFTGNEE1449 pKa = 3.92GTGYY1453 pKa = 9.31TGVFTQAGDD1462 pKa = 3.63DD1463 pKa = 3.84LTITEE1468 pKa = 4.74CTFEE1472 pKa = 4.19NNEE1475 pKa = 3.83GNGYY1479 pKa = 10.58GDD1481 pKa = 3.07IVYY1484 pKa = 10.09AYY1486 pKa = 9.83AGYY1489 pKa = 10.69DD1490 pKa = 3.36VTITDD1495 pKa = 3.61STINGDD1501 pKa = 3.39DD1502 pKa = 3.8TEE1504 pKa = 4.6FVAGSGSVTATGNTVNDD1521 pKa = 3.46VVVAEE1526 pKa = 4.42GLVLTAIDD1534 pKa = 4.81DD1535 pKa = 3.91LTITEE1540 pKa = 4.72VINGEE1545 pKa = 4.26NITVVVKK1552 pKa = 9.68ATSDD1556 pKa = 3.52DD1557 pKa = 4.45SIVTTGTVDD1566 pKa = 4.16LYY1568 pKa = 11.75VGDD1571 pKa = 4.11TLISSDD1577 pKa = 4.23CAADD1581 pKa = 3.24AAGFNVTVNTNLYY1594 pKa = 9.78GDD1596 pKa = 3.84NEE1598 pKa = 4.44VTIKK1602 pKa = 11.0YY1603 pKa = 9.88YY1604 pKa = 10.63DD1605 pKa = 3.69DD1606 pKa = 3.72SGVYY1610 pKa = 9.85VSSEE1614 pKa = 3.72KK1615 pKa = 10.55TIDD1618 pKa = 3.46LTIDD1622 pKa = 4.19MIPATIDD1629 pKa = 2.47ITTPVDD1635 pKa = 4.31VIATDD1640 pKa = 3.37ATVIPFTVTSGDD1652 pKa = 3.23EE1653 pKa = 4.19VLNHH1657 pKa = 5.5GTVTVKK1663 pKa = 10.24VVNEE1667 pKa = 3.93NGEE1670 pKa = 4.35PLVGTPDD1677 pKa = 3.31QTIDD1681 pKa = 3.66LAIDD1685 pKa = 3.5NPEE1688 pKa = 3.97FTVTLYY1694 pKa = 10.99EE1695 pKa = 3.67GTYY1698 pKa = 10.42YY1699 pKa = 11.36YY1700 pKa = 10.94NLSYY1704 pKa = 11.52ADD1706 pKa = 4.31DD1707 pKa = 5.69DD1708 pKa = 4.42YY1709 pKa = 12.15VADD1712 pKa = 3.7NVTIEE1717 pKa = 4.34VIASKK1722 pKa = 10.89LDD1724 pKa = 3.49AYY1726 pKa = 10.58VAADD1730 pKa = 3.73DD1731 pKa = 3.98EE1732 pKa = 4.52EE1733 pKa = 6.79GYY1735 pKa = 10.67FDD1737 pKa = 4.67EE1738 pKa = 6.52DD1739 pKa = 3.26ITVTVYY1745 pKa = 9.15ITDD1748 pKa = 3.73EE1749 pKa = 4.44DD1750 pKa = 4.54DD1751 pKa = 3.57EE1752 pKa = 5.43AVTQGTLSFVDD1763 pKa = 3.42EE1764 pKa = 5.4DD1765 pKa = 4.54GNDD1768 pKa = 3.58VIDD1771 pKa = 5.52PITITGEE1778 pKa = 3.79QTTATFNYY1786 pKa = 8.92PLAGQYY1792 pKa = 10.82DD1793 pKa = 3.75ITIKK1797 pKa = 11.25YY1798 pKa = 10.25EE1799 pKa = 4.01DD1800 pKa = 4.21GKK1802 pKa = 11.38YY1803 pKa = 9.69KK1804 pKa = 10.65AADD1807 pKa = 3.38WDD1809 pKa = 3.77LTITVFSKK1817 pKa = 10.28EE1818 pKa = 3.95AEE1820 pKa = 4.19INTTNAIDD1828 pKa = 3.75VYY1830 pKa = 10.58AGEE1833 pKa = 5.87DD1834 pKa = 3.12ITITANVLCDD1844 pKa = 4.25DD1845 pKa = 4.21EE1846 pKa = 5.81PITVGKK1852 pKa = 10.08LVLYY1856 pKa = 10.62KK1857 pKa = 10.48DD1858 pKa = 4.14DD1859 pKa = 4.12EE1860 pKa = 4.65VVDD1863 pKa = 4.03EE1864 pKa = 5.23CEE1866 pKa = 4.35LTTGTATFNIPAYY1879 pKa = 9.68TEE1881 pKa = 4.22ATQEE1885 pKa = 4.3TYY1887 pKa = 10.17VLKK1890 pKa = 11.29YY1891 pKa = 9.74EE1892 pKa = 4.37GNGNYY1897 pKa = 9.01EE1898 pKa = 4.24VEE1900 pKa = 4.64DD1901 pKa = 4.28DD1902 pKa = 3.89ATVVITVTQLPATINVNPTTINTIATDD1929 pKa = 3.39ATSIPFTVTSGDD1941 pKa = 3.36EE1942 pKa = 4.09VLTVGTVRR1950 pKa = 11.84LKK1952 pKa = 10.8AVNILGQAIVGTPDD1966 pKa = 3.12QVIDD1970 pKa = 4.78LSTQEE1975 pKa = 3.98PVFTVTVFEE1984 pKa = 3.88GTYY1987 pKa = 10.12YY1988 pKa = 11.36YY1989 pKa = 10.95NLSYY1993 pKa = 11.43EE1994 pKa = 4.07NVKK1997 pKa = 10.75YY1998 pKa = 9.47VTDD2001 pKa = 3.71NVTVTVVASKK2011 pKa = 10.46VQATIVADD2019 pKa = 3.98DD2020 pKa = 4.59VINGYY2025 pKa = 9.53IDD2027 pKa = 4.08EE2028 pKa = 4.93DD2029 pKa = 4.18TPIVIKK2035 pKa = 10.76IEE2037 pKa = 4.48DD2038 pKa = 3.95GEE2040 pKa = 4.76GNAVTQGTITLLKK2053 pKa = 10.33EE2054 pKa = 3.96GMPLNSYY2061 pKa = 9.87EE2062 pKa = 4.18VTGEE2066 pKa = 3.72NTTIKK2071 pKa = 10.4LVYY2074 pKa = 9.75RR2075 pKa = 11.84DD2076 pKa = 3.73VATEE2080 pKa = 4.62TITLRR2085 pKa = 11.84YY2086 pKa = 9.66EE2087 pKa = 4.13DD2088 pKa = 3.93GKK2090 pKa = 10.0YY2091 pKa = 7.74TASDD2095 pKa = 3.31KK2096 pKa = 11.33DD2097 pKa = 3.58VTINIHH2103 pKa = 6.1KK2104 pKa = 10.5VPTTTSVEE2112 pKa = 4.11DD2113 pKa = 3.55QNVKK2117 pKa = 10.2VDD2119 pKa = 3.77DD2120 pKa = 4.38TVTLTATVLDD2130 pKa = 4.14KK2131 pKa = 11.48DD2132 pKa = 4.2NNPVTTGTIYY2142 pKa = 10.64FKK2144 pKa = 11.22DD2145 pKa = 3.29EE2146 pKa = 4.81DD2147 pKa = 4.23GNIVHH2152 pKa = 6.53TVILNNGEE2160 pKa = 4.12EE2161 pKa = 4.19PVYY2164 pKa = 10.91SYY2166 pKa = 9.57TASDD2170 pKa = 5.54AITQTYY2176 pKa = 8.35TILYY2180 pKa = 8.67RR2181 pKa = 11.84GSSKK2185 pKa = 10.74YY2186 pKa = 10.75VNSTATATVTVTKK2199 pKa = 10.64YY2200 pKa = 9.32DD2201 pKa = 3.28TTLTVNSPTVNVDD2214 pKa = 3.23DD2215 pKa = 4.63TVTITATLVDD2225 pKa = 4.35EE2226 pKa = 4.81NNNPVTAGKK2235 pKa = 9.76VQFKK2239 pKa = 10.42DD2240 pKa = 3.45GEE2242 pKa = 4.45GNIVYY2247 pKa = 7.76TANLANGDD2255 pKa = 4.13EE2256 pKa = 4.51LVYY2259 pKa = 10.66SYY2261 pKa = 10.83TSSLEE2266 pKa = 3.85GVEE2269 pKa = 5.23DD2270 pKa = 3.3ITVSYY2275 pKa = 10.49LGTYY2279 pKa = 9.61KK2280 pKa = 10.82YY2281 pKa = 11.15EE2282 pKa = 4.1NDD2284 pKa = 3.44TAVATVTTNKK2294 pKa = 9.9IEE2296 pKa = 4.11VTINTDD2302 pKa = 2.64KK2303 pKa = 11.56DD2304 pKa = 3.65EE2305 pKa = 4.63YY2306 pKa = 11.29SDD2308 pKa = 4.62LFGVDD2313 pKa = 3.17IPITITITDD2322 pKa = 3.82GQGNAITQGTITIYY2336 pKa = 10.97EE2337 pKa = 4.29DD2338 pKa = 3.42DD2339 pKa = 4.04AVVNTTTITGEE2350 pKa = 4.04STTFTFNYY2358 pKa = 8.26PQAGTHH2364 pKa = 5.83NLVIKK2369 pKa = 10.1YY2370 pKa = 10.51DD2371 pKa = 3.59NYY2373 pKa = 11.06KK2374 pKa = 10.69YY2375 pKa = 10.34SAEE2378 pKa = 4.09DD2379 pKa = 3.41KK2380 pKa = 10.54EE2381 pKa = 4.73VVVDD2385 pKa = 4.19AEE2387 pKa = 4.19ARR2389 pKa = 11.84EE2390 pKa = 4.19ATIITSDD2397 pKa = 2.76VDD2399 pKa = 3.79AFVGDD2404 pKa = 4.27DD2405 pKa = 3.65VVITATVEE2413 pKa = 3.91SDD2415 pKa = 3.14GVEE2418 pKa = 3.98VTEE2421 pKa = 4.56GKK2423 pKa = 9.89IRR2425 pKa = 11.84FINSDD2430 pKa = 3.19GDD2432 pKa = 3.79VLAEE2436 pKa = 4.48CDD2438 pKa = 4.39LSNGPATYY2446 pKa = 10.64DD2447 pKa = 3.1FGVITEE2453 pKa = 4.26VFDD2456 pKa = 5.32DD2457 pKa = 5.06EE2458 pKa = 5.15ISVEE2462 pKa = 4.31YY2463 pKa = 11.14VSDD2466 pKa = 3.31NYY2468 pKa = 11.21YY2469 pKa = 11.17ADD2471 pKa = 4.71DD2472 pKa = 3.51EE2473 pKa = 4.86TIIVEE2478 pKa = 4.67VIKK2481 pKa = 11.08QMADD2485 pKa = 3.23VVLTTSDD2492 pKa = 3.41VAIATPITVTANVTYY2507 pKa = 10.09EE2508 pKa = 4.55DD2509 pKa = 4.0EE2510 pKa = 5.65PINQGQIIFTDD2521 pKa = 3.36ANGNVIDD2528 pKa = 4.35TVNVVDD2534 pKa = 6.05GIATITVQYY2543 pKa = 10.7DD2544 pKa = 3.28DD2545 pKa = 3.99VGTYY2549 pKa = 9.1TINAEE2554 pKa = 4.39FVDD2557 pKa = 3.85SAYY2560 pKa = 10.34EE2561 pKa = 4.02GEE2563 pKa = 4.25EE2564 pKa = 4.31NIDD2567 pKa = 3.03ITINKK2572 pKa = 9.09IPVTLAISEE2581 pKa = 4.39DD2582 pKa = 3.36QTIAVGDD2589 pKa = 3.94TATITATVTSEE2600 pKa = 4.21DD2601 pKa = 3.73GFVNAGKK2608 pKa = 10.82VIFTKK2613 pKa = 10.11GTTKK2617 pKa = 10.31LAEE2620 pKa = 4.21VNVVDD2625 pKa = 5.34GVASFDD2631 pKa = 3.83YY2632 pKa = 10.84TPTTSGSVDD2641 pKa = 2.71ITAKK2645 pKa = 10.4YY2646 pKa = 10.39VPDD2649 pKa = 5.53DD2650 pKa = 3.88IYY2652 pKa = 11.46SIDD2655 pKa = 4.55EE2656 pKa = 4.14DD2657 pKa = 4.32TATCTVTADD2666 pKa = 3.73KK2667 pKa = 11.56VNTTTTLDD2675 pKa = 4.02DD2676 pKa = 3.62VTLTAGKK2683 pKa = 8.01TVTLTARR2690 pKa = 11.84ITASDD2695 pKa = 3.69NSIVSAGKK2703 pKa = 10.02VAFKK2707 pKa = 11.47VNGKK2711 pKa = 6.5TLKK2714 pKa = 10.36DD2715 pKa = 3.51ANGKK2719 pKa = 9.31VIYY2722 pKa = 10.12AKK2724 pKa = 10.65VVDD2727 pKa = 5.06GVATYY2732 pKa = 9.89EE2733 pKa = 4.21YY2734 pKa = 9.63EE2735 pKa = 4.32VPSDD2739 pKa = 3.73LVGKK2743 pKa = 9.88NVTIEE2748 pKa = 3.95AVYY2751 pKa = 10.59SGSSKK2756 pKa = 10.47YY2757 pKa = 10.6LKK2759 pKa = 11.07SNDD2762 pKa = 3.26KK2763 pKa = 9.91PAEE2766 pKa = 4.29PKK2768 pKa = 9.62TVLSGVADD2776 pKa = 3.62IEE2778 pKa = 4.31ITSAATVTKK2787 pKa = 10.7GEE2789 pKa = 4.16NATFTVKK2796 pKa = 9.23VTDD2799 pKa = 3.25NGANVNGGKK2808 pKa = 9.73VVLKK2812 pKa = 10.85INGKK2816 pKa = 6.42TLKK2819 pKa = 9.42DD2820 pKa = 3.48TNGKK2824 pKa = 9.38VIYY2827 pKa = 10.34ANVVDD2832 pKa = 6.02GIASVEE2838 pKa = 3.88YY2839 pKa = 10.42LIPEE2843 pKa = 4.11SMKK2846 pKa = 11.11SKK2848 pKa = 10.66DD2849 pKa = 3.6YY2850 pKa = 10.08TLSAVFTSSNYY2861 pKa = 8.71EE2862 pKa = 3.74RR2863 pKa = 11.84CEE2865 pKa = 3.97TNQTITVQQ2873 pKa = 3.14
MM1 pKa = 7.28NKK3 pKa = 10.02KK4 pKa = 9.29NVKK7 pKa = 9.49IFTFISLIFVALLIIGGVSAAVDD30 pKa = 3.91DD31 pKa = 4.88SPAATVDD38 pKa = 3.84DD39 pKa = 4.2DD40 pKa = 5.0TITADD45 pKa = 3.63AVTASSDD52 pKa = 3.51VQSNNEE58 pKa = 4.07IITNEE63 pKa = 4.06AIKK66 pKa = 10.31EE67 pKa = 4.0EE68 pKa = 4.39RR69 pKa = 11.84SVKK72 pKa = 10.05GAQQQLPANDD82 pKa = 3.47YY83 pKa = 11.15SEE85 pKa = 5.8LKK87 pKa = 9.53TAVNTAKK94 pKa = 9.97MDD96 pKa = 4.65DD97 pKa = 3.94NDD99 pKa = 3.86ANSYY103 pKa = 10.23VISLSQSGTYY113 pKa = 9.88EE114 pKa = 3.26VDD116 pKa = 4.94APIKK120 pKa = 7.27WTSMGNPTLTIEE132 pKa = 4.56GNGATITGNSNQFFTINSGRR152 pKa = 11.84TLIINNIIIDD162 pKa = 4.04GTSADD167 pKa = 4.57DD168 pKa = 4.9GGAINNNGTITLTNSIIKK186 pKa = 10.46NSIATNGGAIYY197 pKa = 10.46SIGTVNLEE205 pKa = 3.96NVTLQANEE213 pKa = 3.8ATKK216 pKa = 10.57KK217 pKa = 10.67GGAIYY222 pKa = 9.07STGTVNAKK230 pKa = 10.1NVTFKK235 pKa = 11.47DD236 pKa = 3.42NLVTDD241 pKa = 5.35GSHH244 pKa = 6.96GDD246 pKa = 3.46NDD248 pKa = 4.16GGAGIYY254 pKa = 7.0TTGAIYY260 pKa = 10.32IEE262 pKa = 5.14DD263 pKa = 3.71STFDD267 pKa = 3.87SNIGQYY273 pKa = 10.22TDD275 pKa = 3.51TSSSSNGADD284 pKa = 2.83GGAIRR289 pKa = 11.84VKK291 pKa = 10.91DD292 pKa = 4.37SISDD296 pKa = 3.67MIITNTTFTNNKK308 pKa = 8.08GRR310 pKa = 11.84HH311 pKa = 5.09GGALLICDD319 pKa = 4.42DD320 pKa = 4.14EE321 pKa = 4.83GRR323 pKa = 11.84NQGIKK328 pKa = 10.2KK329 pKa = 8.24ITGSTFTGNQAIYY342 pKa = 9.96GGAIEE347 pKa = 5.0VYY349 pKa = 9.93NDD351 pKa = 4.53LIIEE355 pKa = 4.29DD356 pKa = 4.24SVFEE360 pKa = 4.26EE361 pKa = 4.49NSVKK365 pKa = 10.87GIGSGNRR372 pKa = 11.84NPLGGAICVNDD383 pKa = 4.22LVDD386 pKa = 3.94NGAPGSLSVKK396 pKa = 9.11NTTFEE401 pKa = 4.49KK402 pKa = 9.8NTASTTFEE410 pKa = 4.38EE411 pKa = 5.3GTTNYY416 pKa = 10.51GSGGAIYY423 pKa = 10.56NSGPGATIEE432 pKa = 3.97NCTFTEE438 pKa = 4.02NEE440 pKa = 4.42AYY442 pKa = 10.24DD443 pKa = 3.65GGAIEE448 pKa = 6.02DD449 pKa = 4.15EE450 pKa = 4.58ATSSTIKK457 pKa = 10.87DD458 pKa = 3.47SVFEE462 pKa = 4.01QNTAVEE468 pKa = 4.22TGGAIFTINNGTGTTANINNCTFTEE493 pKa = 4.17NSANNGGAIATIGNTTMNIDD513 pKa = 3.48EE514 pKa = 5.14CSFDD518 pKa = 4.12QNTATSNGGAYY529 pKa = 10.18YY530 pKa = 9.0STWDD534 pKa = 3.46TYY536 pKa = 11.71NLPRR540 pKa = 11.84LFKK543 pKa = 10.36HH544 pKa = 6.85ASITNSNFTDD554 pKa = 3.47NTANDD559 pKa = 3.44YY560 pKa = 10.18PAIYY564 pKa = 9.79DD565 pKa = 3.93SNSGPFNGGSSSTVIDD581 pKa = 3.27NCKK584 pKa = 10.47FEE586 pKa = 6.13DD587 pKa = 3.87NVATSASGSTIYY599 pKa = 10.13TRR601 pKa = 11.84YY602 pKa = 10.52ASTSITNSNISDD614 pKa = 3.72TNNRR618 pKa = 11.84AIASVWNNGVANMEE632 pKa = 3.97NDD634 pKa = 3.14IVNGLDD640 pKa = 3.26VDD642 pKa = 4.38SMNNGNLEE650 pKa = 4.25VSVSNYY656 pKa = 10.55AEE658 pKa = 3.96LVAITDD664 pKa = 3.74VLNNQYY670 pKa = 11.17NSADD674 pKa = 3.24PVYY677 pKa = 10.91INFTGDD683 pKa = 2.93AVYY686 pKa = 10.55TEE688 pKa = 4.69TEE690 pKa = 4.24PIAYY694 pKa = 9.55EE695 pKa = 4.27NINCPVTFIGNGKK708 pKa = 8.1TIDD711 pKa = 3.6ANGMQFVTIGEE722 pKa = 4.5GKK724 pKa = 10.26SLTIRR729 pKa = 11.84NLTIKK734 pKa = 10.3NAQADD739 pKa = 3.58NGAAVLNYY747 pKa = 10.61GSLTVNSDD755 pKa = 3.67SVFEE759 pKa = 5.12DD760 pKa = 3.53NSALYY765 pKa = 10.41NGGAIYY771 pKa = 9.06STGNLTITKK780 pKa = 9.64TNFTNNEE787 pKa = 3.92VTTHH791 pKa = 5.65QGAGQKK797 pKa = 10.39DD798 pKa = 4.0YY799 pKa = 11.56GGGAICSLGKK809 pKa = 10.71LSVQTSNFVEE819 pKa = 4.22NTAAHH824 pKa = 6.68NDD826 pKa = 3.52VEE828 pKa = 4.58PNGDD832 pKa = 3.55GGVAGAILVLNTTQEE847 pKa = 4.06VSITTSNFTKK857 pKa = 10.55NDD859 pKa = 3.14GRR861 pKa = 11.84HH862 pKa = 5.69GGAITINNNDD872 pKa = 3.5KK873 pKa = 11.28EE874 pKa = 4.39NTKK877 pKa = 10.52KK878 pKa = 9.35VTINKK883 pKa = 9.66NNFVEE888 pKa = 4.35NTALYY893 pKa = 9.95GAAIDD898 pKa = 4.61TYY900 pKa = 10.55QQANITNNNFTKK912 pKa = 9.96NTVTGQGSGDD922 pKa = 3.82RR923 pKa = 11.84VPMGAAICANQGDD936 pKa = 4.41YY937 pKa = 10.88EE938 pKa = 4.36YY939 pKa = 10.9TLTLINNTFKK949 pKa = 11.12EE950 pKa = 4.47NEE952 pKa = 4.1AQDD955 pKa = 3.91NGCGGVMLTMPDD967 pKa = 3.34STIVSSNNVYY977 pKa = 10.57EE978 pKa = 4.08NNKK981 pKa = 10.54AYY983 pKa = 8.36DD984 pKa = 3.52TGVACIQGSATFTNDD999 pKa = 2.54TFTGNEE1005 pKa = 3.92GTGYY1009 pKa = 9.31TGVFTQAGDD1018 pKa = 3.34EE1019 pKa = 4.12LTITGCTFEE1028 pKa = 4.74NNEE1031 pKa = 3.85GNGYY1035 pKa = 10.8GDD1037 pKa = 2.79IAYY1040 pKa = 9.51AYY1042 pKa = 8.95EE1043 pKa = 4.76GYY1045 pKa = 10.33EE1046 pKa = 3.93VTITDD1051 pKa = 3.39STIITEE1057 pKa = 4.27NEE1059 pKa = 3.9FGDD1062 pKa = 4.36LMSPANSDD1070 pKa = 3.53DD1071 pKa = 4.28FEE1073 pKa = 4.42GTNVKK1078 pKa = 10.43VNGVTFAYY1086 pKa = 9.76TDD1088 pKa = 3.72FKK1090 pKa = 11.55DD1091 pKa = 4.09PIVFDD1096 pKa = 3.5VADD1099 pKa = 3.77YY1100 pKa = 11.31QEE1102 pKa = 5.3LVDD1105 pKa = 5.5LVALIKK1111 pKa = 10.51SEE1113 pKa = 3.97QIAFNVVANLTGTTYY1128 pKa = 10.88TEE1130 pKa = 4.18TEE1132 pKa = 4.74PIVLDD1137 pKa = 3.39DD1138 pKa = 4.03TFPAEE1143 pKa = 4.02SFTIEE1148 pKa = 4.35GNGKK1152 pKa = 8.21TIDD1155 pKa = 3.44ASGMQFLTVGEE1166 pKa = 4.41GQTVTINNLTVANAQADD1183 pKa = 3.65NGAAIINHH1191 pKa = 6.63GDD1193 pKa = 3.34LTINDD1198 pKa = 4.13AVFEE1202 pKa = 4.94DD1203 pKa = 3.85NQALYY1208 pKa = 10.48RR1209 pKa = 11.84GGAILTDD1216 pKa = 3.38GTLTVNRR1223 pKa = 11.84TKK1225 pKa = 10.02FTNNQVTTHH1234 pKa = 5.85QGAGSKK1240 pKa = 10.39DD1241 pKa = 3.56YY1242 pKa = 11.54GGGAICAFGEE1252 pKa = 4.29LTVDD1256 pKa = 3.52EE1257 pKa = 5.16SVFTANVAAHH1267 pKa = 6.75NDD1269 pKa = 3.5VEE1271 pKa = 4.5PNGDD1275 pKa = 3.55GGVAGAILILNNSEE1289 pKa = 5.54DD1290 pKa = 3.49ITITNSNFTQNTGRR1304 pKa = 11.84HH1305 pKa = 5.4GGAITINDD1313 pKa = 3.63NLHH1316 pKa = 6.57RR1317 pKa = 11.84DD1318 pKa = 3.75EE1319 pKa = 4.51GTVTIDD1325 pKa = 4.97SNNFDD1330 pKa = 4.61NNDD1333 pKa = 3.6ALYY1336 pKa = 10.46GAAIDD1341 pKa = 4.27TFHH1344 pKa = 7.26SAIITNNNFTNNWIDD1359 pKa = 3.68GQGSGDD1365 pKa = 3.96RR1366 pKa = 11.84VPMGAAICINNGGDD1380 pKa = 3.54PDD1382 pKa = 3.85YY1383 pKa = 11.24TITLEE1388 pKa = 4.0NNIFRR1393 pKa = 11.84GNEE1396 pKa = 3.79AKK1398 pKa = 10.83DD1399 pKa = 3.51NGCAGAVFTMPDD1411 pKa = 3.16TTLNSANNVYY1421 pKa = 10.16EE1422 pKa = 4.0NNKK1425 pKa = 10.54AYY1427 pKa = 8.35DD1428 pKa = 3.6TGVATIQGIATFTNDD1443 pKa = 2.92TFTGNEE1449 pKa = 3.92GTGYY1453 pKa = 9.31TGVFTQAGDD1462 pKa = 3.63DD1463 pKa = 3.84LTITEE1468 pKa = 4.74CTFEE1472 pKa = 4.19NNEE1475 pKa = 3.83GNGYY1479 pKa = 10.58GDD1481 pKa = 3.07IVYY1484 pKa = 10.09AYY1486 pKa = 9.83AGYY1489 pKa = 10.69DD1490 pKa = 3.36VTITDD1495 pKa = 3.61STINGDD1501 pKa = 3.39DD1502 pKa = 3.8TEE1504 pKa = 4.6FVAGSGSVTATGNTVNDD1521 pKa = 3.46VVVAEE1526 pKa = 4.42GLVLTAIDD1534 pKa = 4.81DD1535 pKa = 3.91LTITEE1540 pKa = 4.72VINGEE1545 pKa = 4.26NITVVVKK1552 pKa = 9.68ATSDD1556 pKa = 3.52DD1557 pKa = 4.45SIVTTGTVDD1566 pKa = 4.16LYY1568 pKa = 11.75VGDD1571 pKa = 4.11TLISSDD1577 pKa = 4.23CAADD1581 pKa = 3.24AAGFNVTVNTNLYY1594 pKa = 9.78GDD1596 pKa = 3.84NEE1598 pKa = 4.44VTIKK1602 pKa = 11.0YY1603 pKa = 9.88YY1604 pKa = 10.63DD1605 pKa = 3.69DD1606 pKa = 3.72SGVYY1610 pKa = 9.85VSSEE1614 pKa = 3.72KK1615 pKa = 10.55TIDD1618 pKa = 3.46LTIDD1622 pKa = 4.19MIPATIDD1629 pKa = 2.47ITTPVDD1635 pKa = 4.31VIATDD1640 pKa = 3.37ATVIPFTVTSGDD1652 pKa = 3.23EE1653 pKa = 4.19VLNHH1657 pKa = 5.5GTVTVKK1663 pKa = 10.24VVNEE1667 pKa = 3.93NGEE1670 pKa = 4.35PLVGTPDD1677 pKa = 3.31QTIDD1681 pKa = 3.66LAIDD1685 pKa = 3.5NPEE1688 pKa = 3.97FTVTLYY1694 pKa = 10.99EE1695 pKa = 3.67GTYY1698 pKa = 10.42YY1699 pKa = 11.36YY1700 pKa = 10.94NLSYY1704 pKa = 11.52ADD1706 pKa = 4.31DD1707 pKa = 5.69DD1708 pKa = 4.42YY1709 pKa = 12.15VADD1712 pKa = 3.7NVTIEE1717 pKa = 4.34VIASKK1722 pKa = 10.89LDD1724 pKa = 3.49AYY1726 pKa = 10.58VAADD1730 pKa = 3.73DD1731 pKa = 3.98EE1732 pKa = 4.52EE1733 pKa = 6.79GYY1735 pKa = 10.67FDD1737 pKa = 4.67EE1738 pKa = 6.52DD1739 pKa = 3.26ITVTVYY1745 pKa = 9.15ITDD1748 pKa = 3.73EE1749 pKa = 4.44DD1750 pKa = 4.54DD1751 pKa = 3.57EE1752 pKa = 5.43AVTQGTLSFVDD1763 pKa = 3.42EE1764 pKa = 5.4DD1765 pKa = 4.54GNDD1768 pKa = 3.58VIDD1771 pKa = 5.52PITITGEE1778 pKa = 3.79QTTATFNYY1786 pKa = 8.92PLAGQYY1792 pKa = 10.82DD1793 pKa = 3.75ITIKK1797 pKa = 11.25YY1798 pKa = 10.25EE1799 pKa = 4.01DD1800 pKa = 4.21GKK1802 pKa = 11.38YY1803 pKa = 9.69KK1804 pKa = 10.65AADD1807 pKa = 3.38WDD1809 pKa = 3.77LTITVFSKK1817 pKa = 10.28EE1818 pKa = 3.95AEE1820 pKa = 4.19INTTNAIDD1828 pKa = 3.75VYY1830 pKa = 10.58AGEE1833 pKa = 5.87DD1834 pKa = 3.12ITITANVLCDD1844 pKa = 4.25DD1845 pKa = 4.21EE1846 pKa = 5.81PITVGKK1852 pKa = 10.08LVLYY1856 pKa = 10.62KK1857 pKa = 10.48DD1858 pKa = 4.14DD1859 pKa = 4.12EE1860 pKa = 4.65VVDD1863 pKa = 4.03EE1864 pKa = 5.23CEE1866 pKa = 4.35LTTGTATFNIPAYY1879 pKa = 9.68TEE1881 pKa = 4.22ATQEE1885 pKa = 4.3TYY1887 pKa = 10.17VLKK1890 pKa = 11.29YY1891 pKa = 9.74EE1892 pKa = 4.37GNGNYY1897 pKa = 9.01EE1898 pKa = 4.24VEE1900 pKa = 4.64DD1901 pKa = 4.28DD1902 pKa = 3.89ATVVITVTQLPATINVNPTTINTIATDD1929 pKa = 3.39ATSIPFTVTSGDD1941 pKa = 3.36EE1942 pKa = 4.09VLTVGTVRR1950 pKa = 11.84LKK1952 pKa = 10.8AVNILGQAIVGTPDD1966 pKa = 3.12QVIDD1970 pKa = 4.78LSTQEE1975 pKa = 3.98PVFTVTVFEE1984 pKa = 3.88GTYY1987 pKa = 10.12YY1988 pKa = 11.36YY1989 pKa = 10.95NLSYY1993 pKa = 11.43EE1994 pKa = 4.07NVKK1997 pKa = 10.75YY1998 pKa = 9.47VTDD2001 pKa = 3.71NVTVTVVASKK2011 pKa = 10.46VQATIVADD2019 pKa = 3.98DD2020 pKa = 4.59VINGYY2025 pKa = 9.53IDD2027 pKa = 4.08EE2028 pKa = 4.93DD2029 pKa = 4.18TPIVIKK2035 pKa = 10.76IEE2037 pKa = 4.48DD2038 pKa = 3.95GEE2040 pKa = 4.76GNAVTQGTITLLKK2053 pKa = 10.33EE2054 pKa = 3.96GMPLNSYY2061 pKa = 9.87EE2062 pKa = 4.18VTGEE2066 pKa = 3.72NTTIKK2071 pKa = 10.4LVYY2074 pKa = 9.75RR2075 pKa = 11.84DD2076 pKa = 3.73VATEE2080 pKa = 4.62TITLRR2085 pKa = 11.84YY2086 pKa = 9.66EE2087 pKa = 4.13DD2088 pKa = 3.93GKK2090 pKa = 10.0YY2091 pKa = 7.74TASDD2095 pKa = 3.31KK2096 pKa = 11.33DD2097 pKa = 3.58VTINIHH2103 pKa = 6.1KK2104 pKa = 10.5VPTTTSVEE2112 pKa = 4.11DD2113 pKa = 3.55QNVKK2117 pKa = 10.2VDD2119 pKa = 3.77DD2120 pKa = 4.38TVTLTATVLDD2130 pKa = 4.14KK2131 pKa = 11.48DD2132 pKa = 4.2NNPVTTGTIYY2142 pKa = 10.64FKK2144 pKa = 11.22DD2145 pKa = 3.29EE2146 pKa = 4.81DD2147 pKa = 4.23GNIVHH2152 pKa = 6.53TVILNNGEE2160 pKa = 4.12EE2161 pKa = 4.19PVYY2164 pKa = 10.91SYY2166 pKa = 9.57TASDD2170 pKa = 5.54AITQTYY2176 pKa = 8.35TILYY2180 pKa = 8.67RR2181 pKa = 11.84GSSKK2185 pKa = 10.74YY2186 pKa = 10.75VNSTATATVTVTKK2199 pKa = 10.64YY2200 pKa = 9.32DD2201 pKa = 3.28TTLTVNSPTVNVDD2214 pKa = 3.23DD2215 pKa = 4.63TVTITATLVDD2225 pKa = 4.35EE2226 pKa = 4.81NNNPVTAGKK2235 pKa = 9.76VQFKK2239 pKa = 10.42DD2240 pKa = 3.45GEE2242 pKa = 4.45GNIVYY2247 pKa = 7.76TANLANGDD2255 pKa = 4.13EE2256 pKa = 4.51LVYY2259 pKa = 10.66SYY2261 pKa = 10.83TSSLEE2266 pKa = 3.85GVEE2269 pKa = 5.23DD2270 pKa = 3.3ITVSYY2275 pKa = 10.49LGTYY2279 pKa = 9.61KK2280 pKa = 10.82YY2281 pKa = 11.15EE2282 pKa = 4.1NDD2284 pKa = 3.44TAVATVTTNKK2294 pKa = 9.9IEE2296 pKa = 4.11VTINTDD2302 pKa = 2.64KK2303 pKa = 11.56DD2304 pKa = 3.65EE2305 pKa = 4.63YY2306 pKa = 11.29SDD2308 pKa = 4.62LFGVDD2313 pKa = 3.17IPITITITDD2322 pKa = 3.82GQGNAITQGTITIYY2336 pKa = 10.97EE2337 pKa = 4.29DD2338 pKa = 3.42DD2339 pKa = 4.04AVVNTTTITGEE2350 pKa = 4.04STTFTFNYY2358 pKa = 8.26PQAGTHH2364 pKa = 5.83NLVIKK2369 pKa = 10.1YY2370 pKa = 10.51DD2371 pKa = 3.59NYY2373 pKa = 11.06KK2374 pKa = 10.69YY2375 pKa = 10.34SAEE2378 pKa = 4.09DD2379 pKa = 3.41KK2380 pKa = 10.54EE2381 pKa = 4.73VVVDD2385 pKa = 4.19AEE2387 pKa = 4.19ARR2389 pKa = 11.84EE2390 pKa = 4.19ATIITSDD2397 pKa = 2.76VDD2399 pKa = 3.79AFVGDD2404 pKa = 4.27DD2405 pKa = 3.65VVITATVEE2413 pKa = 3.91SDD2415 pKa = 3.14GVEE2418 pKa = 3.98VTEE2421 pKa = 4.56GKK2423 pKa = 9.89IRR2425 pKa = 11.84FINSDD2430 pKa = 3.19GDD2432 pKa = 3.79VLAEE2436 pKa = 4.48CDD2438 pKa = 4.39LSNGPATYY2446 pKa = 10.64DD2447 pKa = 3.1FGVITEE2453 pKa = 4.26VFDD2456 pKa = 5.32DD2457 pKa = 5.06EE2458 pKa = 5.15ISVEE2462 pKa = 4.31YY2463 pKa = 11.14VSDD2466 pKa = 3.31NYY2468 pKa = 11.21YY2469 pKa = 11.17ADD2471 pKa = 4.71DD2472 pKa = 3.51EE2473 pKa = 4.86TIIVEE2478 pKa = 4.67VIKK2481 pKa = 11.08QMADD2485 pKa = 3.23VVLTTSDD2492 pKa = 3.41VAIATPITVTANVTYY2507 pKa = 10.09EE2508 pKa = 4.55DD2509 pKa = 4.0EE2510 pKa = 5.65PINQGQIIFTDD2521 pKa = 3.36ANGNVIDD2528 pKa = 4.35TVNVVDD2534 pKa = 6.05GIATITVQYY2543 pKa = 10.7DD2544 pKa = 3.28DD2545 pKa = 3.99VGTYY2549 pKa = 9.1TINAEE2554 pKa = 4.39FVDD2557 pKa = 3.85SAYY2560 pKa = 10.34EE2561 pKa = 4.02GEE2563 pKa = 4.25EE2564 pKa = 4.31NIDD2567 pKa = 3.03ITINKK2572 pKa = 9.09IPVTLAISEE2581 pKa = 4.39DD2582 pKa = 3.36QTIAVGDD2589 pKa = 3.94TATITATVTSEE2600 pKa = 4.21DD2601 pKa = 3.73GFVNAGKK2608 pKa = 10.82VIFTKK2613 pKa = 10.11GTTKK2617 pKa = 10.31LAEE2620 pKa = 4.21VNVVDD2625 pKa = 5.34GVASFDD2631 pKa = 3.83YY2632 pKa = 10.84TPTTSGSVDD2641 pKa = 2.71ITAKK2645 pKa = 10.4YY2646 pKa = 10.39VPDD2649 pKa = 5.53DD2650 pKa = 3.88IYY2652 pKa = 11.46SIDD2655 pKa = 4.55EE2656 pKa = 4.14DD2657 pKa = 4.32TATCTVTADD2666 pKa = 3.73KK2667 pKa = 11.56VNTTTTLDD2675 pKa = 4.02DD2676 pKa = 3.62VTLTAGKK2683 pKa = 8.01TVTLTARR2690 pKa = 11.84ITASDD2695 pKa = 3.69NSIVSAGKK2703 pKa = 10.02VAFKK2707 pKa = 11.47VNGKK2711 pKa = 6.5TLKK2714 pKa = 10.36DD2715 pKa = 3.51ANGKK2719 pKa = 9.31VIYY2722 pKa = 10.12AKK2724 pKa = 10.65VVDD2727 pKa = 5.06GVATYY2732 pKa = 9.89EE2733 pKa = 4.21YY2734 pKa = 9.63EE2735 pKa = 4.32VPSDD2739 pKa = 3.73LVGKK2743 pKa = 9.88NVTIEE2748 pKa = 3.95AVYY2751 pKa = 10.59SGSSKK2756 pKa = 10.47YY2757 pKa = 10.6LKK2759 pKa = 11.07SNDD2762 pKa = 3.26KK2763 pKa = 9.91PAEE2766 pKa = 4.29PKK2768 pKa = 9.62TVLSGVADD2776 pKa = 3.62IEE2778 pKa = 4.31ITSAATVTKK2787 pKa = 10.7GEE2789 pKa = 4.16NATFTVKK2796 pKa = 9.23VTDD2799 pKa = 3.25NGANVNGGKK2808 pKa = 9.73VVLKK2812 pKa = 10.85INGKK2816 pKa = 6.42TLKK2819 pKa = 9.42DD2820 pKa = 3.48TNGKK2824 pKa = 9.38VIYY2827 pKa = 10.34ANVVDD2832 pKa = 6.02GIASVEE2838 pKa = 3.88YY2839 pKa = 10.42LIPEE2843 pKa = 4.11SMKK2846 pKa = 11.11SKK2848 pKa = 10.66DD2849 pKa = 3.6YY2850 pKa = 10.08TLSAVFTSSNYY2861 pKa = 8.71EE2862 pKa = 3.74RR2863 pKa = 11.84CEE2865 pKa = 3.97TNQTITVQQ2873 pKa = 3.14
Molecular weight: 304.98 kDa
Isoelectric point according different methods:
Protein with the highest isoelectric point:
>tr|A0A2Z4L7Z3|A0A2Z4L7Z3_9EURY Uncharacterized protein OS=Methanosphaera sp. BMS OX=1789762 GN=AW729_03900 PE=4 SV=1
MM1 pKa = 7.59SKK3 pKa = 10.58NKK5 pKa = 9.89KK6 pKa = 9.87LPEE9 pKa = 4.5KK10 pKa = 10.41IRR12 pKa = 11.84LAKK15 pKa = 9.01KK16 pKa = 7.52TKK18 pKa = 7.69QNRR21 pKa = 11.84RR22 pKa = 11.84VPIFAMMKK30 pKa = 8.74TSRR33 pKa = 11.84KK34 pKa = 9.59LRR36 pKa = 11.84THH38 pKa = 6.39PKK40 pKa = 7.85ARR42 pKa = 11.84QWRR45 pKa = 11.84RR46 pKa = 11.84SKK48 pKa = 10.85IKK50 pKa = 10.31VV51 pKa = 3.11
MM1 pKa = 7.59SKK3 pKa = 10.58NKK5 pKa = 9.89KK6 pKa = 9.87LPEE9 pKa = 4.5KK10 pKa = 10.41IRR12 pKa = 11.84LAKK15 pKa = 9.01KK16 pKa = 7.52TKK18 pKa = 7.69QNRR21 pKa = 11.84RR22 pKa = 11.84VPIFAMMKK30 pKa = 8.74TSRR33 pKa = 11.84KK34 pKa = 9.59LRR36 pKa = 11.84THH38 pKa = 6.39PKK40 pKa = 7.85ARR42 pKa = 11.84QWRR45 pKa = 11.84RR46 pKa = 11.84SKK48 pKa = 10.85IKK50 pKa = 10.31VV51 pKa = 3.11
Molecular weight: 6.23 kDa
Isoelectric point according different methods:
Peptides (in silico digests for buttom-up proteomics)
Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.| Try ESI |
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| ChTry ESI |
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| ArgC ESI |
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| LysN ESI |
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| TryLysC ESI |
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| Try MALDI |
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| ChTry MALDI |
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| ArgC MALDI |
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| LysN MALDI |
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| TryLysC MALDI |
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| Try LTQ |
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| ChTry LTQ |
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| ArgC LTQ |
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| LysN LTQ |
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| TryLysC LTQ |
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| Try MSlow |
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| ChTry MSlow |
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| ArgC MSlow |
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| LysN MSlow |
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| TryLysC MSlow |
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| Try MShigh |
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| ChTry MShigh |
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| ArgC MShigh |
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| LysN MShigh |
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| TryLysC MShigh |
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General Statistics
Number of major isoforms |
Number of additional isoforms |
Number of all proteins |
Number of amino acids |
Min. Seq. Length |
Max. Seq. Length |
Avg. Seq. Length |
Avg. Mol. Weight |
|---|---|---|---|---|---|---|---|
0 |
768877 |
43 |
9830 |
366.0 |
41.16 |
Amino acid frequency
Ala |
Cys |
Asp |
Glu |
Phe |
Gly |
His |
Ile |
Lys |
Leu |
|---|---|---|---|---|---|---|---|---|---|
5.353 ± 0.059 | 1.104 ± 0.029 |
6.736 ± 0.065 | 6.721 ± 0.081 |
3.637 ± 0.055 | 5.803 ± 0.069 |
1.574 ± 0.032 | 9.613 ± 0.055 |
7.327 ± 0.105 | 8.177 ± 0.098 |
Met |
Asn |
Gln |
Pro |
Arg |
Ser |
Thr |
Val |
Trp |
Tyr |
|---|---|---|---|---|---|---|---|---|---|
2.187 ± 0.042 | 8.023 ± 0.156 |
2.856 ± 0.037 | 2.723 ± 0.034 |
2.936 ± 0.056 | 6.406 ± 0.052 |
7.148 ± 0.201 | 6.481 ± 0.114 |
0.556 ± 0.018 | 4.64 ± 0.053 |
Most of the basic statistics you can see at this page can be downloaded from this CSV file
See this proteome in:
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here
| Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 | Contact: Lukasz P. Kozlowski |