Amino acid dipepetide frequency for Cacao swollen shoot Togo A virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.483AlaAla: 5.483 ± 3.428
0.0AlaCys: 0.0 ± 0.0
2.531AlaAsp: 2.531 ± 0.764
3.796AlaGlu: 3.796 ± 1.851
2.952AlaPhe: 2.952 ± 1.408
2.109AlaGly: 2.109 ± 0.831
1.687AlaHis: 1.687 ± 0.715
4.639AlaIle: 4.639 ± 3.741
2.109AlaLys: 2.109 ± 2.546
4.218AlaLeu: 4.218 ± 3.16
1.265AlaMet: 1.265 ± 0.604
2.109AlaAsn: 2.109 ± 0.742
2.531AlaPro: 2.531 ± 1.207
3.796AlaGln: 3.796 ± 1.951
3.796AlaArg: 3.796 ± 1.07
3.374AlaSer: 3.374 ± 0.962
2.952AlaThr: 2.952 ± 3.041
4.639AlaVal: 4.639 ± 3.736
0.422AlaTrp: 0.422 ± 0.201
4.218AlaTyr: 4.218 ± 1.268
0.0AlaXaa: 0.0 ± 0.0
Cys
0.844CysAla: 0.844 ± 0.402
1.265CysCys: 1.265 ± 0.604
0.0CysAsp: 0.0 ± 0.0
0.422CysGlu: 0.422 ± 0.201
0.844CysPhe: 0.844 ± 0.402
0.422CysGly: 0.422 ± 0.201
0.422CysHis: 0.422 ± 0.201
0.422CysIle: 0.422 ± 0.201
2.952CysLys: 2.952 ± 1.408
0.422CysLeu: 0.422 ± 1.105
0.422CysMet: 0.422 ± 0.201
1.265CysAsn: 1.265 ± 0.604
1.265CysPro: 1.265 ± 0.604
0.844CysGln: 0.844 ± 0.402
0.0CysArg: 0.0 ± 0.0
1.265CysSer: 1.265 ± 0.604
1.265CysThr: 1.265 ± 0.604
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.844CysTyr: 0.844 ± 0.402
0.0CysXaa: 0.0 ± 0.0
Asp
2.109AspAla: 2.109 ± 0.831
0.422AspCys: 0.422 ± 0.201
2.952AspAsp: 2.952 ± 0.836
3.796AspGlu: 3.796 ± 1.083
1.265AspPhe: 1.265 ± 0.943
2.109AspGly: 2.109 ± 1.244
0.844AspHis: 0.844 ± 0.402
2.531AspIle: 2.531 ± 1.207
3.374AspLys: 3.374 ± 1.996
4.218AspLeu: 4.218 ± 1.466
0.422AspMet: 0.422 ± 0.201
1.265AspAsn: 1.265 ± 0.943
2.952AspPro: 2.952 ± 1.612
3.796AspGln: 3.796 ± 0.93
2.109AspArg: 2.109 ± 1.053
1.687AspSer: 1.687 ± 0.772
3.796AspThr: 3.796 ± 0.93
1.265AspVal: 1.265 ± 0.604
0.844AspTrp: 0.844 ± 0.402
2.952AspTyr: 2.952 ± 1.408
0.0AspXaa: 0.0 ± 0.0
Glu
2.952GluAla: 2.952 ± 1.878
0.844GluCys: 0.844 ± 0.402
6.748GluAsp: 6.748 ± 1.892
18.136GluGlu: 18.136 ± 5.924
1.265GluPhe: 1.265 ± 0.604
5.061GluGly: 5.061 ± 2.415
2.531GluHis: 2.531 ± 1.207
6.326GluIle: 6.326 ± 2.002
8.857GluLys: 8.857 ± 7.661
4.639GluLeu: 4.639 ± 0.993
1.265GluMet: 1.265 ± 0.824
3.796GluAsn: 3.796 ± 1.231
2.109GluPro: 2.109 ± 2.478
4.639GluGln: 4.639 ± 1.755
2.531GluArg: 2.531 ± 0.843
6.748GluSer: 6.748 ± 2.287
4.639GluThr: 4.639 ± 2.213
4.218GluVal: 4.218 ± 0.993
1.265GluTrp: 1.265 ± 0.744
2.109GluTyr: 2.109 ± 0.742
0.0GluXaa: 0.0 ± 0.0
Phe
2.109PheAla: 2.109 ± 1.006
0.844PheCys: 0.844 ± 0.402
1.265PheAsp: 1.265 ± 0.744
0.844PheGlu: 0.844 ± 0.402
0.422PhePhe: 0.422 ± 0.201
0.844PheGly: 0.844 ± 0.913
1.687PheHis: 1.687 ± 0.805
3.374PheIle: 3.374 ± 1.074
2.531PheLys: 2.531 ± 1.276
2.952PheLeu: 2.952 ± 1.408
0.844PheMet: 0.844 ± 0.402
1.265PheAsn: 1.265 ± 0.604
0.844PhePro: 0.844 ± 0.402
2.109PheGln: 2.109 ± 0.831
2.531PheArg: 2.531 ± 0.904
2.952PheSer: 2.952 ± 1.408
0.844PheThr: 0.844 ± 0.913
0.844PheVal: 0.844 ± 0.402
0.422PheTrp: 0.422 ± 0.201
1.265PheTyr: 1.265 ± 0.604
0.0PheXaa: 0.0 ± 0.0
Gly
1.265GlyAla: 1.265 ± 0.604
0.844GlyCys: 0.844 ± 0.402
2.531GlyAsp: 2.531 ± 1.207
3.796GlyGlu: 3.796 ± 1.083
1.687GlyPhe: 1.687 ± 0.772
1.265GlyGly: 1.265 ± 0.604
2.952GlyHis: 2.952 ± 1.408
3.374GlyIle: 3.374 ± 1.554
4.639GlyLys: 4.639 ± 1.805
4.639GlyLeu: 4.639 ± 1.599
2.531GlyMet: 2.531 ± 1.207
2.531GlyAsn: 2.531 ± 0.819
1.265GlyPro: 1.265 ± 0.604
1.265GlyGln: 1.265 ± 1.391
5.061GlyArg: 5.061 ± 1.421
2.109GlySer: 2.109 ± 1.006
3.796GlyThr: 3.796 ± 1.124
2.952GlyVal: 2.952 ± 2.268
0.844GlyTrp: 0.844 ± 0.402
1.687GlyTyr: 1.687 ± 0.805
0.0GlyXaa: 0.0 ± 0.0
His
2.531HisAla: 2.531 ± 1.207
0.844HisCys: 0.844 ± 0.402
0.844HisAsp: 0.844 ± 0.402
1.265HisGlu: 1.265 ± 0.943
0.844HisPhe: 0.844 ± 0.402
1.265HisGly: 1.265 ± 0.943
0.844HisHis: 0.844 ± 1.054
2.109HisIle: 2.109 ± 1.006
1.265HisLys: 1.265 ± 0.744
2.531HisLeu: 2.531 ± 0.843
0.844HisMet: 0.844 ± 0.384
1.265HisAsn: 1.265 ± 0.744
0.0HisPro: 0.0 ± 0.0
2.531HisGln: 2.531 ± 1.207
2.109HisArg: 2.109 ± 1.006
1.687HisSer: 1.687 ± 0.865
2.109HisThr: 2.109 ± 0.742
0.844HisVal: 0.844 ± 0.402
0.844HisTrp: 0.844 ± 0.402
0.844HisTyr: 0.844 ± 0.402
0.0HisXaa: 0.0 ± 0.0
Ile
4.218IleAla: 4.218 ± 0.993
2.531IleCys: 2.531 ± 0.764
2.531IleAsp: 2.531 ± 1.207
5.061IleGlu: 5.061 ± 1.081
2.531IlePhe: 2.531 ± 0.835
3.374IleGly: 3.374 ± 1.61
1.687IleHis: 1.687 ± 0.805
3.374IleIle: 3.374 ± 0.999
4.639IleLys: 4.639 ± 1.082
6.748IleLeu: 6.748 ± 1.656
0.0IleMet: 0.0 ± 0.0
2.109IleAsn: 2.109 ± 1.006
3.374IlePro: 3.374 ± 1.996
4.218IleGln: 4.218 ± 1.484
3.374IleArg: 3.374 ± 1.61
3.796IleSer: 3.796 ± 0.93
3.796IleThr: 3.796 ± 1.851
3.796IleVal: 3.796 ± 1.01
0.422IleTrp: 0.422 ± 0.201
1.687IleTyr: 1.687 ± 0.865
0.0IleXaa: 0.0 ± 0.0
Lys
4.639LysAla: 4.639 ± 2.208
0.844LysCys: 0.844 ± 0.402
3.374LysAsp: 3.374 ± 1.996
8.013LysGlu: 8.013 ± 5.923
0.844LysPhe: 0.844 ± 0.402
3.374LysGly: 3.374 ± 3.316
2.109LysHis: 2.109 ± 1.006
3.796LysIle: 3.796 ± 2.795
6.748LysLys: 6.748 ± 7.535
9.279LysLeu: 9.279 ± 3.434
4.639LysMet: 4.639 ± 5.401
3.374LysAsn: 3.374 ± 1.431
3.374LysPro: 3.374 ± 1.007
2.952LysGln: 2.952 ± 2.605
6.748LysArg: 6.748 ± 2.381
2.952LysSer: 2.952 ± 0.933
3.796LysThr: 3.796 ± 1.231
2.952LysVal: 2.952 ± 2.605
0.422LysTrp: 0.422 ± 0.201
0.0LysTyr: 0.0 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
6.748LeuAla: 6.748 ± 4.312
1.265LeuCys: 1.265 ± 0.604
4.639LeuAsp: 4.639 ± 2.484
7.17LeuGlu: 7.17 ± 3.63
2.109LeuPhe: 2.109 ± 0.781
5.483LeuGly: 5.483 ± 1.359
1.687LeuHis: 1.687 ± 1.407
3.796LeuIle: 3.796 ± 1.409
5.905LeuLys: 5.905 ± 1.369
6.326LeuLeu: 6.326 ± 1.966
0.0LeuMet: 0.0 ± 0.0
3.374LeuAsn: 3.374 ± 1.074
3.374LeuPro: 3.374 ± 0.999
4.639LeuGln: 4.639 ± 0.839
4.639LeuArg: 4.639 ± 1.755
7.17LeuSer: 7.17 ± 1.807
6.326LeuThr: 6.326 ± 1.215
6.326LeuVal: 6.326 ± 1.215
0.422LeuTrp: 0.422 ± 0.201
3.374LeuTyr: 3.374 ± 0.999
0.0LeuXaa: 0.0 ± 0.0
Met
1.265MetAla: 1.265 ± 0.604
0.422MetCys: 0.422 ± 0.201
0.422MetAsp: 0.422 ± 0.201
3.374MetGlu: 3.374 ± 1.731
0.0MetPhe: 0.0 ± 0.0
0.422MetGly: 0.422 ± 0.201
0.0MetHis: 0.0 ± 0.0
0.422MetIle: 0.422 ± 0.201
3.374MetLys: 3.374 ± 2.548
0.844MetLeu: 0.844 ± 0.402
1.265MetMet: 1.265 ± 0.824
0.844MetAsn: 0.844 ± 0.913
2.109MetPro: 2.109 ± 1.006
0.844MetGln: 0.844 ± 0.402
1.687MetArg: 1.687 ± 1.826
1.687MetSer: 1.687 ± 0.715
4.218MetThr: 4.218 ± 4.08
1.687MetVal: 1.687 ± 0.805
0.0MetTrp: 0.0 ± 0.0
0.422MetTyr: 0.422 ± 0.201
0.0MetXaa: 0.0 ± 0.0
Asn
0.844AsnAla: 0.844 ± 0.402
0.0AsnCys: 0.0 ± 0.0
0.422AsnAsp: 0.422 ± 0.201
3.374AsnGlu: 3.374 ± 1.61
1.265AsnPhe: 1.265 ± 0.604
2.531AsnGly: 2.531 ± 1.207
1.265AsnHis: 1.265 ± 0.943
2.109AsnIle: 2.109 ± 1.006
3.796AsnLys: 3.796 ± 1.231
5.905AsnLeu: 5.905 ± 3.176
0.844AsnMet: 0.844 ± 0.913
1.687AsnAsn: 1.687 ± 1.217
1.265AsnPro: 1.265 ± 0.604
1.265AsnGln: 1.265 ± 0.744
1.265AsnArg: 1.265 ± 0.744
2.531AsnSer: 2.531 ± 0.764
2.109AsnThr: 2.109 ± 0.742
1.687AsnVal: 1.687 ± 0.772
0.422AsnTrp: 0.422 ± 1.189
2.952AsnTyr: 2.952 ± 0.902
0.0AsnXaa: 0.0 ± 0.0
Pro
3.374ProAla: 3.374 ± 0.948
0.0ProCys: 0.0 ± 0.0
1.687ProAsp: 1.687 ± 0.865
2.952ProGlu: 2.952 ± 0.836
1.265ProPhe: 1.265 ± 0.604
1.687ProGly: 1.687 ± 0.772
1.265ProHis: 1.265 ± 0.604
3.374ProIle: 3.374 ± 0.884
2.531ProLys: 2.531 ± 3.266
4.639ProLeu: 4.639 ± 1.017
1.687ProMet: 1.687 ± 0.762
2.109ProAsn: 2.109 ± 1.006
3.374ProPro: 3.374 ± 0.946
2.531ProGln: 2.531 ± 1.207
2.531ProArg: 2.531 ± 1.207
4.639ProSer: 4.639 ± 1.403
2.109ProThr: 2.109 ± 0.781
1.687ProVal: 1.687 ± 0.805
0.422ProTrp: 0.422 ± 0.201
1.265ProTyr: 1.265 ± 1.687
0.0ProXaa: 0.0 ± 0.0
Gln
4.218GlnAla: 4.218 ± 2.259
0.844GlnCys: 0.844 ± 0.402
1.687GlnAsp: 1.687 ± 0.772
6.748GlnGlu: 6.748 ± 1.69
2.109GlnPhe: 2.109 ± 1.006
3.374GlnGly: 3.374 ± 0.948
1.265GlnHis: 1.265 ± 0.943
3.374GlnIle: 3.374 ± 0.691
2.531GlnLys: 2.531 ± 1.136
4.639GlnLeu: 4.639 ± 2.394
0.422GlnMet: 0.422 ± 0.755
2.109GlnAsn: 2.109 ± 1.808
2.952GlnPro: 2.952 ± 1.033
5.905GlnGln: 5.905 ± 1.443
3.374GlnArg: 3.374 ± 1.61
2.109GlnSer: 2.109 ± 0.831
3.374GlnThr: 3.374 ± 1.61
2.531GlnVal: 2.531 ± 1.207
2.109GlnTrp: 2.109 ± 0.742
1.265GlnTyr: 1.265 ± 0.824
0.0GlnXaa: 0.0 ± 0.0
Arg
2.109ArgAla: 2.109 ± 1.351
0.0ArgCys: 0.0 ± 0.0
3.796ArgAsp: 3.796 ± 1.684
2.531ArgGlu: 2.531 ± 0.819
1.265ArgPhe: 1.265 ± 0.604
2.952ArgGly: 2.952 ± 0.902
0.844ArgHis: 0.844 ± 0.402
3.374ArgIle: 3.374 ± 1.61
5.905ArgLys: 5.905 ± 5.819
6.326ArgLeu: 6.326 ± 1.483
2.952ArgMet: 2.952 ± 1.589
1.687ArgAsn: 1.687 ± 0.805
2.531ArgPro: 2.531 ± 0.835
2.952ArgGln: 2.952 ± 0.902
7.592ArgArg: 7.592 ± 1.758
4.639ArgSer: 4.639 ± 1.532
2.109ArgThr: 2.109 ± 1.006
5.905ArgVal: 5.905 ± 2.172
2.109ArgTrp: 2.109 ± 0.742
2.531ArgTyr: 2.531 ± 1.207
0.0ArgXaa: 0.0 ± 0.0
Ser
2.952SerAla: 2.952 ± 3.572
2.109SerCys: 2.109 ± 1.006
2.109SerAsp: 2.109 ± 0.831
5.061SerGlu: 5.061 ± 1.758
1.687SerPhe: 1.687 ± 0.805
2.952SerGly: 2.952 ± 1.408
2.531SerHis: 2.531 ± 0.819
4.218SerIle: 4.218 ± 1.484
3.796SerLys: 3.796 ± 1.231
4.218SerLeu: 4.218 ± 1.854
1.265SerMet: 1.265 ± 1.538
1.687SerAsn: 1.687 ± 0.805
3.374SerPro: 3.374 ± 0.946
2.952SerGln: 2.952 ± 1.045
5.061SerArg: 5.061 ± 1.758
6.326SerSer: 6.326 ± 3.401
5.905SerThr: 5.905 ± 1.184
3.374SerVal: 3.374 ± 1.61
0.422SerTrp: 0.422 ± 0.201
0.844SerTyr: 0.844 ± 0.965
0.0SerXaa: 0.0 ± 0.0
Thr
3.796ThrAla: 3.796 ± 0.655
0.844ThrCys: 0.844 ± 0.402
2.531ThrAsp: 2.531 ± 0.764
5.483ThrGlu: 5.483 ± 1.196
2.952ThrPhe: 2.952 ± 1.91
5.483ThrGly: 5.483 ± 1.277
1.265ThrHis: 1.265 ± 0.943
6.748ThrIle: 6.748 ± 0.982
4.218ThrLys: 4.218 ± 1.189
3.796ThrLeu: 3.796 ± 0.829
2.109ThrMet: 2.109 ± 1.006
2.109ThrAsn: 2.109 ± 0.742
3.374ThrPro: 3.374 ± 0.946
2.531ThrGln: 2.531 ± 0.843
4.218ThrArg: 4.218 ± 0.993
4.218ThrSer: 4.218 ± 0.68
4.639ThrThr: 4.639 ± 1.403
4.639ThrVal: 4.639 ± 2.213
1.265ThrTrp: 1.265 ± 0.824
0.422ThrTyr: 0.422 ± 0.201
0.0ThrXaa: 0.0 ± 0.0
Val
3.796ValAla: 3.796 ± 0.868
0.0ValCys: 0.0 ± 0.0
2.109ValAsp: 2.109 ± 1.053
3.796ValGlu: 3.796 ± 2.232
5.483ValPhe: 5.483 ± 1.023
3.374ValGly: 3.374 ± 0.691
1.687ValHis: 1.687 ± 0.805
2.952ValIle: 2.952 ± 0.836
2.531ValLys: 2.531 ± 0.835
2.952ValLeu: 2.952 ± 1.033
1.265ValMet: 1.265 ± 0.604
1.687ValAsn: 1.687 ± 1.407
2.531ValPro: 2.531 ± 0.843
5.061ValGln: 5.061 ± 2.62
2.531ValArg: 2.531 ± 1.136
0.422ValSer: 0.422 ± 0.201
5.483ValThr: 5.483 ± 1.676
2.531ValVal: 2.531 ± 1.198
1.687ValTrp: 1.687 ± 0.805
1.687ValTyr: 1.687 ± 0.805
0.0ValXaa: 0.0 ± 0.0
Trp
0.844TrpAla: 0.844 ± 1.054
0.0TrpCys: 0.0 ± 0.0
0.844TrpAsp: 0.844 ± 0.402
1.687TrpGlu: 1.687 ± 0.715
0.0TrpPhe: 0.0 ± 0.0
0.844TrpGly: 0.844 ± 0.402
0.0TrpHis: 0.0 ± 0.0
1.687TrpIle: 1.687 ± 0.805
0.422TrpLys: 0.422 ± 0.201
1.687TrpLeu: 1.687 ± 0.805
0.422TrpMet: 0.422 ± 0.201
0.0TrpAsn: 0.0 ± 0.0
0.844TrpPro: 0.844 ± 0.913
0.844TrpGln: 0.844 ± 0.402
0.844TrpArg: 0.844 ± 0.402
0.844TrpSer: 0.844 ± 0.402
1.687TrpThr: 1.687 ± 0.805
0.844TrpVal: 0.844 ± 0.823
0.422TrpTrp: 0.422 ± 0.201
0.422TrpTyr: 0.422 ± 0.938
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.531TyrAla: 2.531 ± 0.843
1.265TyrCys: 1.265 ± 0.604
1.687TyrAsp: 1.687 ± 0.865
3.374TyrGlu: 3.374 ± 1.074
0.0TyrPhe: 0.0 ± 0.0
2.109TyrGly: 2.109 ± 0.781
0.844TyrHis: 0.844 ± 0.402
1.265TyrIle: 1.265 ± 0.604
2.109TyrLys: 2.109 ± 0.741
3.796TyrLeu: 3.796 ± 1.231
0.422TyrMet: 0.422 ± 0.201
1.265TyrAsn: 1.265 ± 0.604
1.687TyrPro: 1.687 ± 0.865
1.687TyrGln: 1.687 ± 0.772
2.109TyrArg: 2.109 ± 0.831
1.687TyrSer: 1.687 ± 0.865
1.687TyrThr: 1.687 ± 0.805
0.844TyrVal: 0.844 ± 0.402
0.422TyrTrp: 0.422 ± 0.201
1.265TyrTyr: 1.265 ± 0.604
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (2372 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski