HIV-1 CRF03_AB

Taxonomy: Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes; Ortervirales; Retroviridae; Orthoretrovirinae; Lentivirus; Human immunodeficiency virus 1; HIV-1 recombinants; HIV-1 circulating recombinant forms

Average proteome isoelectric point is 7.32

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 9 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|Q9Q6W0|Q9Q6W0_9HIV1 Protein Rev OS=HIV-1 CRF03_AB OX=540995 GN=rev PE=3 SV=1
MM1 pKa = 7.19QSLAIAAIVALVVVGIIAIVVGSIVFIEE29 pKa = 3.91YY30 pKa = 10.41RR31 pKa = 11.84KK32 pKa = 9.66ILRR35 pKa = 11.84QRR37 pKa = 11.84KK38 pKa = 8.02IDD40 pKa = 3.69RR41 pKa = 11.84LIDD44 pKa = 4.43RR45 pKa = 11.84IRR47 pKa = 11.84EE48 pKa = 3.87RR49 pKa = 11.84AEE51 pKa = 3.95DD52 pKa = 3.58SGNEE56 pKa = 4.05SEE58 pKa = 5.01GDD60 pKa = 3.47QEE62 pKa = 5.53ALMEE66 pKa = 4.45MGHH69 pKa = 6.54LVPWDD74 pKa = 3.81ADD76 pKa = 3.76DD77 pKa = 4.23LL78 pKa = 4.39

Molecular weight: 8.73 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|Q9Q6W3|Q9Q6W3_9HIV1 Exoribonuclease H (Fragment) OS=HIV-1 CRF03_AB OX=540995 GN=pol PE=3 SV=1
MM1 pKa = 7.3EE2 pKa = 5.21NRR4 pKa = 11.84WQVMIVWQVDD14 pKa = 3.04RR15 pKa = 11.84MRR17 pKa = 11.84IRR19 pKa = 11.84TWNSLVKK26 pKa = 9.66HH27 pKa = 6.66HH28 pKa = 7.07IYY30 pKa = 10.07ISKK33 pKa = 10.1KK34 pKa = 9.13ARR36 pKa = 11.84GWVYY40 pKa = 9.39KK41 pKa = 10.13HH42 pKa = 6.55HH43 pKa = 6.38YY44 pKa = 8.7EE45 pKa = 4.24SRR47 pKa = 11.84NPRR50 pKa = 11.84ISSEE54 pKa = 3.9VHH56 pKa = 5.92IPLGDD61 pKa = 3.41AKK63 pKa = 10.86LVIKK67 pKa = 7.92TYY69 pKa = 9.48WGLHH73 pKa = 4.19TGEE76 pKa = 4.83RR77 pKa = 11.84DD78 pKa = 2.79WHH80 pKa = 6.28LGQGASIEE88 pKa = 4.16WRR90 pKa = 11.84KK91 pKa = 9.44EE92 pKa = 3.85RR93 pKa = 11.84YY94 pKa = 7.6STQVDD99 pKa = 3.82PNLADD104 pKa = 3.66QLIHH108 pKa = 7.2LYY110 pKa = 10.94YY111 pKa = 10.17FDD113 pKa = 5.17CFSEE117 pKa = 4.36SAIRR121 pKa = 11.84NAILGHH127 pKa = 6.04RR128 pKa = 11.84VSPSCEE134 pKa = 3.33YY135 pKa = 10.5RR136 pKa = 11.84AGHH139 pKa = 5.98NKK141 pKa = 9.62VGSLQYY147 pKa = 10.69LALAALRR154 pKa = 11.84TPKK157 pKa = 10.17KK158 pKa = 9.75IKK160 pKa = 10.14PPLPSVTKK168 pKa = 9.62LTEE171 pKa = 4.23DD172 pKa = 3.16RR173 pKa = 11.84WNKK176 pKa = 7.51PQRR179 pKa = 11.84TKK181 pKa = 10.81DD182 pKa = 3.24HH183 pKa = 6.83RR184 pKa = 11.84GSHH187 pKa = 5.16TMSGHH192 pKa = 5.5

Molecular weight: 22.59 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

9

0

9

2877

78

1003

319.7

36.16

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.083 ± 0.399

1.981 ± 0.486

4.414 ± 0.404

6.882 ± 0.534

2.711 ± 0.342

7.334 ± 0.27

2.225 ± 0.634

6.813 ± 0.73

7.369 ± 0.842

7.994 ± 0.284

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.051 ± 0.367

4.101 ± 0.705

5.666 ± 0.605

5.909 ± 0.507

5.77 ± 1.137

5.492 ± 0.686

5.874 ± 0.79

6.152 ± 0.571

2.537 ± 0.24

2.642 ± 0.315
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski