Amino acid dipepetide frequency for Tacheng Tick Virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.275AlaAla: 3.275 ± 1.875
2.069AlaCys: 2.069 ± 0.703
1.896AlaAsp: 1.896 ± 0.16
4.654AlaGlu: 4.654 ± 0.65
2.069AlaPhe: 2.069 ± 0.447
2.586AlaGly: 2.586 ± 0.908
0.517AlaHis: 0.517 ± 0.344
3.965AlaIle: 3.965 ± 0.21
3.448AlaLys: 3.448 ± 0.681
7.93AlaLeu: 7.93 ± 2.169
0.862AlaMet: 0.862 ± 0.265
1.896AlaAsn: 1.896 ± 0.463
2.413AlaPro: 2.413 ± 0.986
2.241AlaGln: 2.241 ± 0.332
2.586AlaArg: 2.586 ± 0.428
4.827AlaSer: 4.827 ± 1.684
3.448AlaThr: 3.448 ± 0.214
4.827AlaVal: 4.827 ± 0.732
1.379AlaTrp: 1.379 ± 1.07
1.551AlaTyr: 1.551 ± 0.368
0.0AlaXaa: 0.0 ± 0.0
Cys
1.724CysAla: 1.724 ± 0.885
1.034CysCys: 1.034 ± 0.245
0.862CysAsp: 0.862 ± 0.443
1.207CysGlu: 1.207 ± 0.218
1.379CysPhe: 1.379 ± 0.177
0.345CysGly: 0.345 ± 0.487
0.862CysHis: 0.862 ± 0.809
1.551CysIle: 1.551 ± 0.559
0.862CysLys: 0.862 ± 0.227
2.758CysLeu: 2.758 ± 0.763
0.517CysMet: 0.517 ± 0.282
1.034CysAsn: 1.034 ± 0.737
1.724CysPro: 1.724 ± 1.148
0.862CysGln: 0.862 ± 0.227
1.379CysArg: 1.379 ± 0.61
2.931CysSer: 2.931 ± 1.706
2.241CysThr: 2.241 ± 0.636
1.379CysVal: 1.379 ± 0.489
0.345CysTrp: 0.345 ± 0.152
0.69CysTyr: 0.69 ± 0.588
0.0CysXaa: 0.0 ± 0.0
Asp
2.931AspAla: 2.931 ± 0.702
1.724AspCys: 1.724 ± 0.521
2.241AspAsp: 2.241 ± 0.636
2.069AspGlu: 2.069 ± 0.547
1.896AspPhe: 1.896 ± 0.463
2.758AspGly: 2.758 ± 1.24
1.034AspHis: 1.034 ± 0.737
3.275AspIle: 3.275 ± 0.46
1.724AspLys: 1.724 ± 0.455
5.344AspLeu: 5.344 ± 1.224
1.551AspMet: 1.551 ± 0.59
1.034AspAsn: 1.034 ± 0.245
2.241AspPro: 2.241 ± 1.067
1.379AspGln: 1.379 ± 0.489
3.275AspArg: 3.275 ± 0.36
4.137AspSer: 4.137 ± 1.014
3.103AspThr: 3.103 ± 0.671
2.413AspVal: 2.413 ± 0.138
1.551AspTrp: 1.551 ± 1.073
1.551AspTyr: 1.551 ± 0.846
0.0AspXaa: 0.0 ± 0.0
Glu
5.172GluAla: 5.172 ± 0.738
1.379GluCys: 1.379 ± 0.313
4.137GluAsp: 4.137 ± 0.586
6.378GluGlu: 6.378 ± 0.958
2.413GluPhe: 2.413 ± 0.423
3.965GluGly: 3.965 ± 0.718
1.724GluHis: 1.724 ± 0.885
3.448GluIle: 3.448 ± 0.981
3.448GluLys: 3.448 ± 0.666
7.413GluLeu: 7.413 ± 2.063
2.241GluMet: 2.241 ± 0.608
2.241GluAsn: 2.241 ± 0.635
1.896GluPro: 1.896 ± 0.536
2.931GluGln: 2.931 ± 0.846
4.654GluArg: 4.654 ± 1.258
5.689GluSer: 5.689 ± 1.608
4.482GluThr: 4.482 ± 0.757
4.654GluVal: 4.654 ± 0.644
0.345GluTrp: 0.345 ± 0.152
1.724GluTyr: 1.724 ± 0.968
0.0GluXaa: 0.0 ± 0.0
Phe
1.896PheAla: 1.896 ± 0.16
1.207PheCys: 1.207 ± 0.524
1.896PheAsp: 1.896 ± 0.952
1.724PheGlu: 1.724 ± 0.382
1.724PhePhe: 1.724 ± 0.382
1.896PheGly: 1.896 ± 0.16
1.379PheHis: 1.379 ± 0.313
2.413PheIle: 2.413 ± 0.504
1.379PheLys: 1.379 ± 0.658
4.137PheLeu: 4.137 ± 0.487
1.034PheMet: 1.034 ± 0.311
1.724PheAsn: 1.724 ± 0.455
1.379PhePro: 1.379 ± 0.595
1.207PheGln: 1.207 ± 0.265
1.896PheArg: 1.896 ± 0.418
4.999PheSer: 4.999 ± 0.699
1.896PheThr: 1.896 ± 0.418
2.069PheVal: 2.069 ± 0.669
0.345PheTrp: 0.345 ± 0.373
2.069PheTyr: 2.069 ± 0.365
0.0PheXaa: 0.0 ± 0.0
Gly
2.758GlyAla: 2.758 ± 0.354
1.379GlyCys: 1.379 ± 1.177
3.965GlyAsp: 3.965 ± 1.496
2.413GlyGlu: 2.413 ± 0.436
1.034GlyPhe: 1.034 ± 0.687
2.069GlyGly: 2.069 ± 0.447
0.517GlyHis: 0.517 ± 0.123
3.275GlyIle: 3.275 ± 0.279
3.965GlyLys: 3.965 ± 0.524
4.999GlyLeu: 4.999 ± 0.361
1.551GlyMet: 1.551 ± 0.309
1.896GlyAsn: 1.896 ± 0.557
2.413GlyPro: 2.413 ± 0.504
1.379GlyGln: 1.379 ± 0.377
3.448GlyArg: 3.448 ± 0.783
4.137GlySer: 4.137 ± 0.122
3.103GlyThr: 3.103 ± 0.932
4.137GlyVal: 4.137 ± 1.875
0.517GlyTrp: 0.517 ± 0.123
1.551GlyTyr: 1.551 ± 0.632
0.0GlyXaa: 0.0 ± 0.0
His
1.034HisAla: 1.034 ± 0.245
0.862HisCys: 0.862 ± 0.227
0.69HisAsp: 0.69 ± 0.157
1.379HisGlu: 1.379 ± 0.528
0.862HisPhe: 0.862 ± 0.518
1.896HisGly: 1.896 ± 0.497
0.862HisHis: 0.862 ± 0.227
1.379HisIle: 1.379 ± 0.313
1.034HisLys: 1.034 ± 0.351
2.069HisLeu: 2.069 ± 0.243
0.862HisMet: 0.862 ± 0.36
0.172HisAsn: 0.172 ± 0.094
1.034HisPro: 1.034 ± 0.618
0.862HisGln: 0.862 ± 0.265
0.862HisArg: 0.862 ± 0.227
3.275HisSer: 3.275 ± 0.729
1.724HisThr: 1.724 ± 0.455
1.551HisVal: 1.551 ± 0.933
0.345HisTrp: 0.345 ± 0.443
0.345HisTyr: 0.345 ± 0.188
0.0HisXaa: 0.0 ± 0.0
Ile
3.448IleAla: 3.448 ± 0.447
1.207IleCys: 1.207 ± 0.408
1.551IleAsp: 1.551 ± 0.379
2.931IleGlu: 2.931 ± 0.846
1.551IlePhe: 1.551 ± 0.559
2.241IleGly: 2.241 ± 0.708
2.241IleHis: 2.241 ± 0.05
2.586IleIle: 2.586 ± 0.23
4.654IleLys: 4.654 ± 0.927
5.861IleLeu: 5.861 ± 0.891
0.69IleMet: 0.69 ± 0.339
2.069IleAsn: 2.069 ± 0.703
1.896IlePro: 1.896 ± 1.033
2.241IleGln: 2.241 ± 0.708
2.758IleArg: 2.758 ± 0.905
6.378IleSer: 6.378 ± 1.116
3.103IleThr: 3.103 ± 0.797
3.62IleVal: 3.62 ± 1.091
0.517IleTrp: 0.517 ± 0.282
1.551IleTyr: 1.551 ± 0.603
0.0IleXaa: 0.0 ± 0.0
Lys
4.137LysAla: 4.137 ± 1.799
1.034LysCys: 1.034 ± 0.688
4.137LysAsp: 4.137 ± 0.534
6.033LysGlu: 6.033 ± 0.948
1.724LysPhe: 1.724 ± 0.672
2.758LysGly: 2.758 ± 0.584
1.724LysHis: 1.724 ± 0.455
2.758LysIle: 2.758 ± 1.643
3.965LysLys: 3.965 ± 1.575
7.413LysLeu: 7.413 ± 0.789
1.724LysMet: 1.724 ± 0.397
1.724LysAsn: 1.724 ± 1.019
2.758LysPro: 2.758 ± 0.159
2.069LysGln: 2.069 ± 0.243
1.724LysArg: 1.724 ± 0.382
3.62LysSer: 3.62 ± 1.446
4.999LysThr: 4.999 ± 0.279
6.033LysVal: 6.033 ± 0.882
0.862LysTrp: 0.862 ± 0.26
2.069LysTyr: 2.069 ± 0.547
0.0LysXaa: 0.0 ± 0.0
Leu
6.378LeuAla: 6.378 ± 1.425
1.724LeuCys: 1.724 ± 0.455
5.172LeuAsp: 5.172 ± 1.146
8.447LeuGlu: 8.447 ± 2.049
4.137LeuPhe: 4.137 ± 0.586
5.861LeuGly: 5.861 ± 0.662
2.413LeuHis: 2.413 ± 0.504
4.137LeuIle: 4.137 ± 1.356
7.93LeuLys: 7.93 ± 1.442
11.377LeuLeu: 11.377 ± 1.751
2.413LeuMet: 2.413 ± 0.531
5.516LeuAsn: 5.516 ± 0.647
6.033LeuPro: 6.033 ± 0.644
4.31LeuGln: 4.31 ± 0.903
4.654LeuArg: 4.654 ± 0.845
10.86LeuSer: 10.86 ± 1.201
5.689LeuThr: 5.689 ± 0.782
6.206LeuVal: 6.206 ± 1.668
0.862LeuTrp: 0.862 ± 0.809
2.586LeuTyr: 2.586 ± 0.46
0.0LeuXaa: 0.0 ± 0.0
Met
1.896MetAla: 1.896 ± 0.582
0.517MetCys: 0.517 ± 0.368
0.69MetAsp: 0.69 ± 0.376
0.69MetGlu: 0.69 ± 0.157
1.034MetPhe: 1.034 ± 0.688
0.345MetGly: 0.345 ± 0.188
0.517MetHis: 0.517 ± 0.404
1.379MetIle: 1.379 ± 0.25
2.586MetLys: 2.586 ± 1.409
2.413MetLeu: 2.413 ± 0.423
0.517MetMet: 0.517 ± 0.282
0.862MetAsn: 0.862 ± 0.265
0.517MetPro: 0.517 ± 0.123
1.034MetGln: 1.034 ± 0.245
1.379MetArg: 1.379 ± 0.489
2.758MetSer: 2.758 ± 0.159
0.862MetThr: 0.862 ± 0.712
2.586MetVal: 2.586 ± 0.791
0.345MetTrp: 0.345 ± 0.152
0.172MetTyr: 0.172 ± 0.094
0.0MetXaa: 0.0 ± 0.0
Asn
1.724AsnAla: 1.724 ± 0.243
1.034AsnCys: 1.034 ± 0.457
0.862AsnAsp: 0.862 ± 0.36
1.207AsnGlu: 1.207 ± 0.658
1.551AsnPhe: 1.551 ± 0.58
0.69AsnGly: 0.69 ± 0.886
0.862AsnHis: 0.862 ± 0.227
2.931AsnIle: 2.931 ± 0.997
3.275AsnLys: 3.275 ± 1.583
4.654AsnLeu: 4.654 ± 1.637
0.69AsnMet: 0.69 ± 0.376
1.724AsnAsn: 1.724 ± 0.1
1.896AsnPro: 1.896 ± 0.481
1.724AsnGln: 1.724 ± 0.542
2.586AsnArg: 2.586 ± 0.515
4.31AsnSer: 4.31 ± 0.646
2.069AsnThr: 2.069 ± 0.491
1.379AsnVal: 1.379 ± 0.724
1.207AsnTrp: 1.207 ± 0.731
1.207AsnTyr: 1.207 ± 0.731
0.0AsnXaa: 0.0 ± 0.0
Pro
1.896ProAla: 1.896 ± 1.059
1.724ProCys: 1.724 ± 0.243
2.413ProAsp: 2.413 ± 0.138
4.654ProGlu: 4.654 ± 1.041
0.862ProPhe: 0.862 ± 0.26
2.413ProGly: 2.413 ± 1.337
0.862ProHis: 0.862 ± 0.227
2.758ProIle: 2.758 ± 0.584
2.241ProLys: 2.241 ± 0.432
3.103ProLeu: 3.103 ± 0.278
1.034ProMet: 1.034 ± 0.564
1.034ProAsn: 1.034 ± 0.457
0.862ProPro: 0.862 ± 0.227
1.034ProGln: 1.034 ± 0.245
2.241ProArg: 2.241 ± 0.635
4.31ProSer: 4.31 ± 1.183
2.758ProThr: 2.758 ± 1.009
2.931ProVal: 2.931 ± 0.767
0.69ProTrp: 0.69 ± 0.329
1.379ProTyr: 1.379 ± 0.595
0.0ProXaa: 0.0 ± 0.0
Gln
2.413GlnAla: 2.413 ± 0.817
1.551GlnCys: 1.551 ± 0.368
1.207GlnAsp: 1.207 ± 0.658
2.758GlnGlu: 2.758 ± 0.623
2.586GlnPhe: 2.586 ± 0.614
1.896GlnGly: 1.896 ± 1.381
1.207GlnHis: 1.207 ± 0.658
1.379GlnIle: 1.379 ± 0.313
2.069GlnLys: 2.069 ± 0.061
3.62GlnLeu: 3.62 ± 0.793
0.862GlnMet: 0.862 ± 0.47
2.069GlnAsn: 2.069 ± 0.47
0.69GlnPro: 0.69 ± 0.157
2.413GlnGln: 2.413 ± 0.138
2.241GlnArg: 2.241 ± 0.502
2.241GlnSer: 2.241 ± 0.283
2.069GlnThr: 2.069 ± 0.061
2.758GlnVal: 2.758 ± 0.309
0.345GlnTrp: 0.345 ± 0.843
1.034GlnTyr: 1.034 ± 0.908
0.0GlnXaa: 0.0 ± 0.0
Arg
2.586ArgAla: 2.586 ± 0.437
1.379ArgCys: 1.379 ± 0.61
2.241ArgAsp: 2.241 ± 0.859
3.792ArgGlu: 3.792 ± 1.286
2.413ArgPhe: 2.413 ± 0.138
1.551ArgGly: 1.551 ± 0.109
1.034ArgHis: 1.034 ± 0.245
2.241ArgIle: 2.241 ± 0.708
2.931ArgLys: 2.931 ± 1.069
8.274ArgLeu: 8.274 ± 1.581
1.379ArgMet: 1.379 ± 0.595
2.413ArgAsn: 2.413 ± 0.436
2.931ArgPro: 2.931 ± 0.74
1.724ArgGln: 1.724 ± 0.683
4.827ArgArg: 4.827 ± 0.646
4.827ArgSer: 4.827 ± 1.097
3.275ArgThr: 3.275 ± 0.46
3.792ArgVal: 3.792 ± 1.096
0.345ArgTrp: 0.345 ± 0.188
1.207ArgTyr: 1.207 ± 0.658
0.0ArgXaa: 0.0 ± 0.0
Ser
5.516SerAla: 5.516 ± 0.318
2.758SerCys: 2.758 ± 1.219
5.689SerAsp: 5.689 ± 1.427
5.344SerGlu: 5.344 ± 0.727
4.482SerPhe: 4.482 ± 1.104
7.24SerGly: 7.24 ± 0.917
1.034SerHis: 1.034 ± 0.564
4.482SerIle: 4.482 ± 1.417
5.344SerLys: 5.344 ± 0.648
10.515SerLeu: 10.515 ± 1.286
1.379SerMet: 1.379 ± 0.376
3.792SerAsn: 3.792 ± 0.429
3.275SerPro: 3.275 ± 0.58
2.069SerGln: 2.069 ± 0.703
5.689SerArg: 5.689 ± 1.648
12.584SerSer: 12.584 ± 0.531
7.413SerThr: 7.413 ± 0.789
4.999SerVal: 4.999 ± 0.661
0.862SerTrp: 0.862 ± 1.001
3.275SerTyr: 3.275 ± 0.728
0.0SerXaa: 0.0 ± 0.0
Thr
3.275ThrAla: 3.275 ± 2.006
1.207ThrCys: 1.207 ± 0.816
2.413ThrAsp: 2.413 ± 0.853
6.723ThrGlu: 6.723 ± 1.749
2.586ThrPhe: 2.586 ± 0.33
5.344ThrGly: 5.344 ± 1.639
1.379ThrHis: 1.379 ± 0.313
2.758ThrIle: 2.758 ± 1.231
4.31ThrLys: 4.31 ± 0.273
5.172ThrLeu: 5.172 ± 0.689
0.69ThrMet: 0.69 ± 0.329
2.413ThrAsn: 2.413 ± 0.524
2.586ThrPro: 2.586 ± 1.014
1.551ThrGln: 1.551 ± 0.632
3.448ThrArg: 3.448 ± 0.421
6.378ThrSer: 6.378 ± 1.478
4.137ThrThr: 4.137 ± 0.531
5.516ThrVal: 5.516 ± 0.409
0.862ThrTrp: 0.862 ± 0.746
1.379ThrTyr: 1.379 ± 0.489
0.0ThrXaa: 0.0 ± 0.0
Val
3.275ValAla: 3.275 ± 0.305
0.862ValCys: 0.862 ± 0.518
3.62ValAsp: 3.62 ± 0.612
4.654ValGlu: 4.654 ± 0.185
1.896ValPhe: 1.896 ± 1.052
1.724ValGly: 1.724 ± 0.382
2.069ValHis: 2.069 ± 0.243
4.827ValIle: 4.827 ± 0.646
5.516ValLys: 5.516 ± 0.842
6.378ValLeu: 6.378 ± 1.116
1.896ValMet: 1.896 ± 0.536
2.413ValAsn: 2.413 ± 0.853
3.62ValPro: 3.62 ± 0.127
4.482ValGln: 4.482 ± 1.473
3.448ValArg: 3.448 ± 0.909
6.551ValSer: 6.551 ± 0.906
4.827ValThr: 4.827 ± 0.916
3.965ValVal: 3.965 ± 0.537
0.69ValTrp: 0.69 ± 0.157
0.69ValTyr: 0.69 ± 0.886
0.0ValXaa: 0.0 ± 0.0
Trp
0.69TrpAla: 0.69 ± 1.211
0.172TrpCys: 0.172 ± 0.221
0.172TrpAsp: 0.172 ± 0.094
1.034TrpGlu: 1.034 ± 0.908
0.69TrpPhe: 0.69 ± 0.812
1.034TrpGly: 1.034 ± 0.351
0.172TrpHis: 0.172 ± 0.094
0.0TrpIle: 0.0 ± 0.0
1.379TrpLys: 1.379 ± 0.595
0.862TrpLeu: 0.862 ± 0.265
0.345TrpMet: 0.345 ± 0.443
0.69TrpAsn: 0.69 ± 0.157
0.517TrpPro: 0.517 ± 0.368
0.517TrpGln: 0.517 ± 0.123
0.69TrpArg: 0.69 ± 0.812
1.379TrpSer: 1.379 ± 1.325
1.034TrpThr: 1.034 ± 0.351
1.207TrpVal: 1.207 ± 0.265
0.0TrpTrp: 0.0 ± 0.0
0.345TrpTyr: 0.345 ± 0.152
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.413TyrAla: 2.413 ± 1.048
0.862TyrCys: 0.862 ± 0.227
1.379TyrAsp: 1.379 ± 0.377
2.241TyrGlu: 2.241 ± 0.432
1.379TyrPhe: 1.379 ± 0.528
1.896TyrGly: 1.896 ± 0.15
0.69TyrHis: 0.69 ± 0.305
1.551TyrIle: 1.551 ± 0.309
1.207TyrLys: 1.207 ± 0.265
2.413TyrLeu: 2.413 ± 0.531
0.69TyrMet: 0.69 ± 0.157
0.862TyrAsn: 0.862 ± 0.227
0.517TyrPro: 0.517 ± 0.404
1.379TyrGln: 1.379 ± 0.595
1.379TyrArg: 1.379 ± 0.25
1.724TyrSer: 1.724 ± 0.455
1.896TyrThr: 1.896 ± 1.452
1.379TyrVal: 1.379 ± 0.25
0.517TyrTrp: 0.517 ± 0.123
0.345TyrTyr: 0.345 ± 0.152
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (5802 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski