Amino acid dipepetide frequency for Velvet bean golden mosaic virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.722AlaAla: 2.722 ± 1.286
1.815AlaCys: 1.815 ± 1.69
1.815AlaAsp: 1.815 ± 1.608
5.445AlaGlu: 5.445 ± 3.32
0.907AlaPhe: 0.907 ± 0.845
0.907AlaGly: 0.907 ± 0.693
2.722AlaHis: 2.722 ± 1.01
2.722AlaIle: 2.722 ± 1.614
4.537AlaLys: 4.537 ± 1.28
8.167AlaLeu: 8.167 ± 1.392
0.907AlaMet: 0.907 ± 0.845
0.907AlaAsn: 0.907 ± 0.693
3.63AlaPro: 3.63 ± 1.241
4.537AlaGln: 4.537 ± 2.063
2.722AlaArg: 2.722 ± 1.377
4.537AlaSer: 4.537 ± 1.616
5.445AlaThr: 5.445 ± 2.276
0.0AlaVal: 0.0 ± 0.0
0.907AlaTrp: 0.907 ± 0.693
0.907AlaTyr: 0.907 ± 0.693
0.0AlaXaa: 0.0 ± 0.0
Cys
1.815CysAla: 1.815 ± 1.211
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.907CysGlu: 0.907 ± 0.845
0.907CysPhe: 0.907 ± 0.935
2.722CysGly: 2.722 ± 2.242
0.907CysHis: 0.907 ± 0.693
2.722CysIle: 2.722 ± 1.891
1.815CysLys: 1.815 ± 1.69
0.0CysLeu: 0.0 ± 0.0
0.907CysMet: 0.907 ± 1.011
0.907CysAsn: 0.907 ± 0.693
0.907CysPro: 0.907 ± 1.011
0.907CysGln: 0.907 ± 1.011
0.907CysArg: 0.907 ± 0.693
2.722CysSer: 2.722 ± 1.906
4.537CysThr: 4.537 ± 1.28
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.907CysTyr: 0.907 ± 1.172
0.0CysXaa: 0.0 ± 0.0
Asp
3.63AspAla: 3.63 ± 2.169
0.907AspCys: 0.907 ± 0.935
3.63AspAsp: 3.63 ± 3.34
0.907AspGlu: 0.907 ± 0.845
3.63AspPhe: 3.63 ± 2.275
3.63AspGly: 3.63 ± 2.169
0.907AspHis: 0.907 ± 0.693
3.63AspIle: 3.63 ± 1.049
0.907AspLys: 0.907 ± 1.134
3.63AspLeu: 3.63 ± 1.178
0.0AspMet: 0.0 ± 0.0
2.722AspAsn: 2.722 ± 1.01
1.815AspPro: 1.815 ± 1.05
2.722AspGln: 2.722 ± 1.492
2.722AspArg: 2.722 ± 1.535
2.722AspSer: 2.722 ± 0.927
2.722AspThr: 2.722 ± 1.535
6.352AspVal: 6.352 ± 1.315
0.907AspTrp: 0.907 ± 0.693
0.907AspTyr: 0.907 ± 0.693
0.0AspXaa: 0.0 ± 0.0
Glu
2.722GluAla: 2.722 ± 1.085
0.907GluCys: 0.907 ± 0.693
3.63GluAsp: 3.63 ± 1.639
5.445GluGlu: 5.445 ± 1.857
2.722GluPhe: 2.722 ± 2.078
2.722GluGly: 2.722 ± 1.286
1.815GluHis: 1.815 ± 1.608
1.815GluIle: 1.815 ± 1.695
3.63GluLys: 3.63 ± 2.036
5.445GluLeu: 5.445 ± 2.924
0.0GluMet: 0.0 ± 0.0
2.722GluAsn: 2.722 ± 2.535
0.907GluPro: 0.907 ± 0.845
3.63GluGln: 3.63 ± 1.678
0.907GluArg: 0.907 ± 0.693
3.63GluSer: 3.63 ± 1.598
3.63GluThr: 3.63 ± 1.594
1.815GluVal: 1.815 ± 1.359
0.907GluTrp: 0.907 ± 1.134
0.907GluTyr: 0.907 ± 1.011
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
0.907PheCys: 0.907 ± 0.845
2.722PheAsp: 2.722 ± 1.286
4.537PheGlu: 4.537 ± 1.086
1.815PhePhe: 1.815 ± 0.839
3.63PheGly: 3.63 ± 1.414
0.907PheHis: 0.907 ± 0.693
1.815PheIle: 1.815 ± 1.085
1.815PheLys: 1.815 ± 0.839
4.537PheLeu: 4.537 ± 2.452
2.722PheMet: 2.722 ± 1.177
2.722PheAsn: 2.722 ± 1.773
1.815PhePro: 1.815 ± 1.451
1.815PheGln: 1.815 ± 1.386
5.445PheArg: 5.445 ± 2.249
2.722PheSer: 2.722 ± 1.019
0.907PheThr: 0.907 ± 1.134
0.0PheVal: 0.0 ± 0.0
0.907PheTrp: 0.907 ± 1.134
3.63PheTyr: 3.63 ± 1.403
0.0PheXaa: 0.0 ± 0.0
Gly
2.722GlyAla: 2.722 ± 1.614
2.722GlyCys: 2.722 ± 1.445
3.63GlyAsp: 3.63 ± 2.169
1.815GlyGlu: 1.815 ± 1.608
2.722GlyPhe: 2.722 ± 2.273
2.722GlyGly: 2.722 ± 1.286
1.815GlyHis: 1.815 ± 1.211
2.722GlyIle: 2.722 ± 1.085
7.26GlyLys: 7.26 ± 3.328
1.815GlyLeu: 1.815 ± 1.695
0.907GlyMet: 0.907 ± 1.172
1.815GlyAsn: 1.815 ± 1.69
2.722GlyPro: 2.722 ± 1.286
2.722GlyGln: 2.722 ± 1.884
1.815GlyArg: 1.815 ± 1.386
1.815GlySer: 1.815 ± 1.608
4.537GlyThr: 4.537 ± 1.655
1.815GlyVal: 1.815 ± 2.343
0.0GlyTrp: 0.0 ± 0.0
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
2.722HisAla: 2.722 ± 1.085
0.907HisCys: 0.907 ± 1.134
0.907HisAsp: 0.907 ± 0.845
0.907HisGlu: 0.907 ± 0.693
0.907HisPhe: 0.907 ± 0.693
3.63HisGly: 3.63 ± 1.523
1.815HisHis: 1.815 ± 2.268
1.815HisIle: 1.815 ± 1.211
0.907HisLys: 0.907 ± 1.172
1.815HisLeu: 1.815 ± 1.386
0.0HisMet: 0.0 ± 0.0
3.63HisAsn: 3.63 ± 2.036
1.815HisPro: 1.815 ± 1.05
2.722HisGln: 2.722 ± 2.125
4.537HisArg: 4.537 ± 1.826
0.907HisSer: 0.907 ± 1.134
2.722HisThr: 2.722 ± 2.535
4.537HisVal: 4.537 ± 2.311
0.0HisTrp: 0.0 ± 0.0
2.722HisTyr: 2.722 ± 2.149
0.0HisXaa: 0.0 ± 0.0
Ile
0.907IleAla: 0.907 ± 0.845
0.907IleCys: 0.907 ± 0.693
2.722IleAsp: 2.722 ± 1.614
2.722IleGlu: 2.722 ± 1.464
3.63IlePhe: 3.63 ± 1.594
1.815IleGly: 1.815 ± 1.259
0.907IleHis: 0.907 ± 0.693
0.907IleIle: 0.907 ± 1.134
7.26IleLys: 7.26 ± 2.644
4.537IleLeu: 4.537 ± 2.085
0.907IleMet: 0.907 ± 0.935
3.63IleAsn: 3.63 ± 3.34
0.907IlePro: 0.907 ± 0.693
4.537IleGln: 4.537 ± 2.102
4.537IleArg: 4.537 ± 1.267
4.537IleSer: 4.537 ± 0.957
3.63IleThr: 3.63 ± 1.891
1.815IleVal: 1.815 ± 1.05
1.815IleTrp: 1.815 ± 1.695
1.815IleTyr: 1.815 ± 1.243
0.0IleXaa: 0.0 ± 0.0
Lys
6.352LysAla: 6.352 ± 2.26
1.815LysCys: 1.815 ± 1.085
2.722LysAsp: 2.722 ± 2.078
7.26LysGlu: 7.26 ± 2.497
2.722LysPhe: 2.722 ± 1.393
0.907LysGly: 0.907 ± 0.693
1.815LysHis: 1.815 ± 1.211
1.815LysIle: 1.815 ± 1.259
3.63LysLys: 3.63 ± 3.34
2.722LysLeu: 2.722 ± 1.458
0.0LysMet: 0.0 ± 0.0
6.352LysAsn: 6.352 ± 1.315
3.63LysPro: 3.63 ± 1.241
2.722LysGln: 2.722 ± 1.377
3.63LysArg: 3.63 ± 2.306
7.26LysSer: 7.26 ± 1.241
1.815LysThr: 1.815 ± 0.951
4.537LysVal: 4.537 ± 2.325
0.0LysTrp: 0.0 ± 0.0
4.537LysTyr: 4.537 ± 0.957
0.0LysXaa: 0.0 ± 0.0
Leu
1.815LeuAla: 1.815 ± 1.386
3.63LeuCys: 3.63 ± 1.314
2.722LeuAsp: 2.722 ± 2.078
3.63LeuGlu: 3.63 ± 1.914
3.63LeuPhe: 3.63 ± 2.361
3.63LeuGly: 3.63 ± 1.523
1.815LeuHis: 1.815 ± 1.386
2.722LeuIle: 2.722 ± 2.103
4.537LeuLys: 4.537 ± 2.536
5.445LeuLeu: 5.445 ± 2.278
1.815LeuMet: 1.815 ± 1.871
7.26LeuAsn: 7.26 ± 2.328
5.445LeuPro: 5.445 ± 3.195
2.722LeuGln: 2.722 ± 1.228
9.074LeuArg: 9.074 ± 5.098
8.167LeuSer: 8.167 ± 4.399
3.63LeuThr: 3.63 ± 1.594
0.907LeuVal: 0.907 ± 0.845
0.907LeuTrp: 0.907 ± 1.011
6.352LeuTyr: 6.352 ± 1.623
0.0LeuXaa: 0.0 ± 0.0
Met
1.815MetAla: 1.815 ± 1.69
0.0MetCys: 0.0 ± 0.0
2.722MetAsp: 2.722 ± 1.773
3.63MetGlu: 3.63 ± 1.898
0.907MetPhe: 0.907 ± 0.845
1.815MetGly: 1.815 ± 0.951
1.815MetHis: 1.815 ± 1.608
1.815MetIle: 1.815 ± 1.451
0.0MetLys: 0.0 ± 0.0
1.815MetLeu: 1.815 ± 1.871
0.907MetMet: 0.907 ± 1.172
0.0MetAsn: 0.0 ± 0.0
3.63MetPro: 3.63 ± 1.767
0.907MetGln: 0.907 ± 0.935
1.815MetArg: 1.815 ± 1.608
0.907MetSer: 0.907 ± 0.935
0.0MetThr: 0.0 ± 0.0
1.815MetVal: 1.815 ± 1.243
0.907MetTrp: 0.907 ± 0.845
0.907MetTyr: 0.907 ± 0.845
0.0MetXaa: 0.0 ± 0.0
Asn
6.352AsnAla: 6.352 ± 2.315
0.907AsnCys: 0.907 ± 1.134
4.537AsnAsp: 4.537 ± 1.28
0.907AsnGlu: 0.907 ± 0.845
1.815AsnPhe: 1.815 ± 1.153
2.722AsnGly: 2.722 ± 1.458
5.445AsnHis: 5.445 ± 3.28
4.537AsnIle: 4.537 ± 1.281
1.815AsnLys: 1.815 ± 1.05
6.352AsnLeu: 6.352 ± 3.476
2.722AsnMet: 2.722 ± 1.471
5.445AsnAsn: 5.445 ± 2.147
1.815AsnPro: 1.815 ± 1.243
0.907AsnGln: 0.907 ± 0.693
1.815AsnArg: 1.815 ± 0.839
3.63AsnSer: 3.63 ± 1.178
3.63AsnThr: 3.63 ± 2.215
4.537AsnVal: 4.537 ± 2.519
0.0AsnTrp: 0.0 ± 0.0
2.722AsnTyr: 2.722 ± 1.286
0.0AsnXaa: 0.0 ± 0.0
Pro
2.722ProAla: 2.722 ± 1.535
1.815ProCys: 1.815 ± 0.839
1.815ProAsp: 1.815 ± 1.153
0.907ProGlu: 0.907 ± 0.693
1.815ProPhe: 1.815 ± 0.839
0.907ProGly: 0.907 ± 0.935
4.537ProHis: 4.537 ± 2.519
2.722ProIle: 2.722 ± 1.228
7.26ProLys: 7.26 ± 2.309
5.445ProLeu: 5.445 ± 2.454
2.722ProMet: 2.722 ± 2.535
3.63ProAsn: 3.63 ± 2.132
0.907ProPro: 0.907 ± 1.134
0.907ProGln: 0.907 ± 1.134
3.63ProArg: 3.63 ± 1.848
2.722ProSer: 2.722 ± 2.125
2.722ProThr: 2.722 ± 1.377
0.907ProVal: 0.907 ± 0.845
0.0ProTrp: 0.0 ± 0.0
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
1.815GlnAla: 1.815 ± 0.839
1.815GlnCys: 1.815 ± 1.05
0.0GlnAsp: 0.0 ± 0.0
2.722GlnGlu: 2.722 ± 1.019
0.907GlnPhe: 0.907 ± 0.693
2.722GlnGly: 2.722 ± 1.286
2.722GlnHis: 2.722 ± 1.969
3.63GlnIle: 3.63 ± 1.651
0.907GlnLys: 0.907 ± 1.011
1.815GlnLeu: 1.815 ± 2.343
0.907GlnMet: 0.907 ± 1.172
1.815GlnAsn: 1.815 ± 1.211
1.815GlnPro: 1.815 ± 2.268
1.815GlnGln: 1.815 ± 2.022
1.815GlnArg: 1.815 ± 0.839
4.537GlnSer: 4.537 ± 1.732
0.907GlnThr: 0.907 ± 0.693
6.352GlnVal: 6.352 ± 1.127
0.0GlnTrp: 0.0 ± 0.0
2.722GlnTyr: 2.722 ± 1.085
0.0GlnXaa: 0.0 ± 0.0
Arg
4.537ArgAla: 4.537 ± 2.263
0.907ArgCys: 0.907 ± 1.134
3.63ArgAsp: 3.63 ± 1.414
0.907ArgGlu: 0.907 ± 0.693
4.537ArgPhe: 4.537 ± 3.153
4.537ArgGly: 4.537 ± 1.241
3.63ArgHis: 3.63 ± 3.076
5.445ArgIle: 5.445 ± 1.895
4.537ArgLys: 4.537 ± 1.862
6.352ArgLeu: 6.352 ± 1.127
0.907ArgMet: 0.907 ± 1.172
2.722ArgAsn: 2.722 ± 1.445
3.63ArgPro: 3.63 ± 1.678
2.722ArgGln: 2.722 ± 1.228
9.982ArgArg: 9.982 ± 5.511
2.722ArgSer: 2.722 ± 1.01
4.537ArgThr: 4.537 ± 3.117
1.815ArgVal: 1.815 ± 1.69
0.907ArgTrp: 0.907 ± 0.845
2.722ArgTyr: 2.722 ± 1.458
0.0ArgXaa: 0.0 ± 0.0
Ser
3.63SerAla: 3.63 ± 1.241
1.815SerCys: 1.815 ± 1.306
2.722SerAsp: 2.722 ± 1.085
0.907SerGlu: 0.907 ± 1.134
2.722SerPhe: 2.722 ± 1.286
2.722SerGly: 2.722 ± 2.149
1.815SerHis: 1.815 ± 1.608
7.26SerIle: 7.26 ± 3.07
5.445SerLys: 5.445 ± 1.673
3.63SerLeu: 3.63 ± 1.439
3.63SerMet: 3.63 ± 2.886
6.352SerAsn: 6.352 ± 1.315
3.63SerPro: 3.63 ± 1.977
0.0SerGln: 0.0 ± 0.0
2.722SerArg: 2.722 ± 1.228
9.982SerSer: 9.982 ± 3.349
8.167SerThr: 8.167 ± 2.888
1.815SerVal: 1.815 ± 1.259
0.907SerTrp: 0.907 ± 0.693
1.815SerTyr: 1.815 ± 1.085
0.0SerXaa: 0.0 ± 0.0
Thr
4.537ThrAla: 4.537 ± 1.241
1.815ThrCys: 1.815 ± 2.022
0.907ThrAsp: 0.907 ± 0.935
1.815ThrGlu: 1.815 ± 1.224
2.722ThrPhe: 2.722 ± 1.216
4.537ThrGly: 4.537 ± 2.123
2.722ThrHis: 2.722 ± 1.673
3.63ThrIle: 3.63 ± 1.369
3.63ThrLys: 3.63 ± 2.332
2.722ThrLeu: 2.722 ± 0.927
1.815ThrMet: 1.815 ± 1.695
2.722ThrAsn: 2.722 ± 1.286
4.537ThrPro: 4.537 ± 2.1
2.722ThrGln: 2.722 ± 2.078
5.445ThrArg: 5.445 ± 1.949
3.63ThrSer: 3.63 ± 2.599
4.537ThrThr: 4.537 ± 1.396
3.63ThrVal: 3.63 ± 2.332
0.907ThrTrp: 0.907 ± 0.693
3.63ThrTyr: 3.63 ± 0.949
0.0ThrXaa: 0.0 ± 0.0
Val
0.0ValAla: 0.0 ± 0.0
0.907ValCys: 0.907 ± 1.011
2.722ValAsp: 2.722 ± 1.464
2.722ValGlu: 2.722 ± 1.885
3.63ValPhe: 3.63 ± 3.383
0.907ValGly: 0.907 ± 0.845
0.0ValHis: 0.0 ± 0.0
1.815ValIle: 1.815 ± 1.386
3.63ValLys: 3.63 ± 1.888
6.352ValLeu: 6.352 ± 1.212
0.907ValMet: 0.907 ± 0.845
4.537ValAsn: 4.537 ± 1.684
1.815ValPro: 1.815 ± 0.839
0.907ValGln: 0.907 ± 0.845
1.815ValArg: 1.815 ± 0.839
2.722ValSer: 2.722 ± 2.205
2.722ValThr: 2.722 ± 1.773
1.815ValVal: 1.815 ± 0.839
1.815ValTrp: 1.815 ± 0.839
3.63ValTyr: 3.63 ± 2.332
0.0ValXaa: 0.0 ± 0.0
Trp
2.722TrpAla: 2.722 ± 2.078
0.0TrpCys: 0.0 ± 0.0
1.815TrpAsp: 1.815 ± 1.484
0.907TrpGlu: 0.907 ± 1.172
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
0.907TrpMet: 0.907 ± 0.845
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.907TrpGln: 0.907 ± 0.693
2.722TrpArg: 2.722 ± 1.288
0.0TrpSer: 0.0 ± 0.0
0.907TrpThr: 0.907 ± 0.845
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.907TrpTyr: 0.907 ± 0.693
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.722TyrAla: 2.722 ± 1.535
0.0TyrCys: 0.0 ± 0.0
3.63TyrAsp: 3.63 ± 2.484
0.907TyrGlu: 0.907 ± 0.845
2.722TyrPhe: 2.722 ± 0.927
0.907TyrGly: 0.907 ± 0.693
1.815TyrHis: 1.815 ± 1.085
0.907TyrIle: 0.907 ± 0.845
2.722TyrLys: 2.722 ± 1.393
7.26TyrLeu: 7.26 ± 3.351
3.63TyrMet: 3.63 ± 1.142
2.722TyrAsn: 2.722 ± 0.927
2.722TyrPro: 2.722 ± 1.228
0.907TyrGln: 0.907 ± 0.845
3.63TyrArg: 3.63 ± 2.645
1.815TyrSer: 1.815 ± 1.386
0.907TyrThr: 0.907 ± 0.693
0.907TyrVal: 0.907 ± 0.693
0.0TyrTrp: 0.0 ± 0.0
1.815TyrTyr: 1.815 ± 1.211
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1103 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski