Talaromyces islandicus (Penicillium islandicum)

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Fungi; Dikarya; Ascomycota; saccharomyceta; Pezizomycotina; leotiomyceta;

Average proteome isoelectric point is 6.27

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 9927 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A0U1LRM5|A0A0U1LRM5_TALIS Neurofilament heavy polypeptide OS=Talaromyces islandicus OX=28573 GN=PISL3812_03062 PE=4 SV=1
MM1 pKa = 7.8KK2 pKa = 9.68STLTLATVATLAGLLATGVTAEE24 pKa = 4.69DD25 pKa = 3.27QDD27 pKa = 4.08PYY29 pKa = 11.56LFVAFVQSDD38 pKa = 3.62DD39 pKa = 4.36PLNHH43 pKa = 7.57DD44 pKa = 4.06YY45 pKa = 10.54MFSPGIQVNGDD56 pKa = 3.62TLIHH60 pKa = 6.71LGHH63 pKa = 6.96GGLFFYY69 pKa = 11.09VDD71 pKa = 4.47DD72 pKa = 4.19STSQLVMTADD82 pKa = 3.16NHH84 pKa = 7.26DD85 pKa = 4.21IIGNAWIDD93 pKa = 3.65TNDD96 pKa = 3.39RR97 pKa = 11.84GILKK101 pKa = 10.41FSNDD105 pKa = 3.8PDD107 pKa = 3.47AHH109 pKa = 6.9DD110 pKa = 3.68YY111 pKa = 11.86ALFTRR116 pKa = 11.84DD117 pKa = 3.06YY118 pKa = 11.48DD119 pKa = 4.23DD120 pKa = 3.65RR121 pKa = 11.84TNTLLPQGADD131 pKa = 5.16DD132 pKa = 4.02LWFWCPLDD140 pKa = 3.98DD141 pKa = 5.59AEE143 pKa = 5.02VNGTVAVGQVAGDD156 pKa = 3.52GCEE159 pKa = 3.88QLKK162 pKa = 10.34GVQIAYY168 pKa = 10.5GDD170 pKa = 3.48

Molecular weight: 18.48 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A0U1LP54|A0A0U1LP54_TALIS Catabolic 3-dehydroquinase OS=Talaromyces islandicus OX=28573 GN=qutE PE=3 SV=1
MM1 pKa = 7.63SLTTPPAVPSPFSRR15 pKa = 11.84TASFPSSPGFRR26 pKa = 11.84SRR28 pKa = 11.84LPIPCKK34 pKa = 10.23SPPSIRR40 pKa = 11.84DD41 pKa = 3.43TTPSVPSAPALGSSSSARR59 pKa = 11.84LDD61 pKa = 3.21EE62 pKa = 4.32RR63 pKa = 11.84RR64 pKa = 11.84AARR67 pKa = 11.84DD68 pKa = 3.19ARR70 pKa = 11.84PRR72 pKa = 11.84PWSDD76 pKa = 2.78RR77 pKa = 11.84PTWAPAKK84 pKa = 8.75PRR86 pKa = 11.84CVRR89 pKa = 11.84PSPAQLATLCPRR101 pKa = 11.84RR102 pKa = 11.84LFDD105 pKa = 3.83RR106 pKa = 11.84QQARR110 pKa = 11.84QRR112 pKa = 11.84RR113 pKa = 11.84DD114 pKa = 3.36RR115 pKa = 11.84PWAVSASPCRR125 pKa = 11.84QSQSSTSPSAATSSAAAAIAPSGLRR150 pKa = 11.84GILKK154 pKa = 9.91SRR156 pKa = 11.84CSVPRR161 pKa = 11.84AAKK164 pKa = 10.24KK165 pKa = 10.11KK166 pKa = 8.94VVWSADD172 pKa = 3.37STVVEE177 pKa = 3.92VSRR180 pKa = 11.84WIKK183 pKa = 10.34EE184 pKa = 3.96SEE186 pKa = 4.32EE187 pKa = 4.06YY188 pKa = 10.95DD189 pKa = 3.72DD190 pKa = 5.9DD191 pKa = 5.13NEE193 pKa = 4.41VYY195 pKa = 10.64EE196 pKa = 4.52AMCFF200 pKa = 3.49

Molecular weight: 21.79 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

9927

0

9927

5349850

66

9048

538.9

59.69

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

8.39 ± 0.022

1.158 ± 0.008

5.746 ± 0.016

6.077 ± 0.023

3.834 ± 0.014

6.679 ± 0.021

2.393 ± 0.01

5.156 ± 0.015

4.762 ± 0.019

9.017 ± 0.022

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.094 ± 0.008

3.937 ± 0.012

5.796 ± 0.025

4.095 ± 0.017

5.827 ± 0.019

8.493 ± 0.025

6.017 ± 0.017

6.204 ± 0.018

1.454 ± 0.008

2.868 ± 0.014
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski