Amino acid dipepetide frequency for Sanxia picorna-like virus 4

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.022AlaAla: 3.022 ± 0.0
0.864AlaCys: 0.864 ± 0.0
2.591AlaAsp: 2.591 ± 0.0
0.432AlaGlu: 0.432 ± 0.0
3.886AlaPhe: 3.886 ± 0.0
4.75AlaGly: 4.75 ± 0.0
0.864AlaHis: 0.864 ± 0.0
3.022AlaIle: 3.022 ± 0.0
1.727AlaLys: 1.727 ± 0.0
7.34AlaLeu: 7.34 ± 0.0
0.864AlaMet: 0.864 ± 0.0
3.454AlaAsn: 3.454 ± 0.0
2.159AlaPro: 2.159 ± 0.0
0.864AlaGln: 0.864 ± 0.0
1.295AlaArg: 1.295 ± 0.0
4.318AlaSer: 4.318 ± 0.0
5.613AlaThr: 5.613 ± 0.0
3.022AlaVal: 3.022 ± 0.0
0.864AlaTrp: 0.864 ± 0.0
1.727AlaTyr: 1.727 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
1.295CysAla: 1.295 ± 0.0
0.864CysCys: 0.864 ± 0.0
1.295CysAsp: 1.295 ± 0.0
0.864CysGlu: 0.864 ± 0.0
0.864CysPhe: 0.864 ± 0.0
1.727CysGly: 1.727 ± 0.0
0.432CysHis: 0.432 ± 0.0
1.727CysIle: 1.727 ± 0.0
1.295CysLys: 1.295 ± 0.0
0.432CysLeu: 0.432 ± 0.0
1.295CysMet: 1.295 ± 0.0
0.432CysAsn: 0.432 ± 0.0
1.727CysPro: 1.727 ± 0.0
0.432CysGln: 0.432 ± 0.0
0.432CysArg: 0.432 ± 0.0
2.159CysSer: 2.159 ± 0.0
0.432CysThr: 0.432 ± 0.0
0.864CysVal: 0.864 ± 0.0
1.295CysTrp: 1.295 ± 0.0
0.864CysTyr: 0.864 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.159AspAla: 2.159 ± 0.0
0.864AspCys: 0.864 ± 0.0
5.181AspAsp: 5.181 ± 0.0
3.886AspGlu: 3.886 ± 0.0
3.022AspPhe: 3.022 ± 0.0
3.454AspGly: 3.454 ± 0.0
3.886AspHis: 3.886 ± 0.0
6.045AspIle: 6.045 ± 0.0
5.613AspLys: 5.613 ± 0.0
4.75AspLeu: 4.75 ± 0.0
0.864AspMet: 0.864 ± 0.0
4.75AspAsn: 4.75 ± 0.0
1.295AspPro: 1.295 ± 0.0
0.864AspGln: 0.864 ± 0.0
3.022AspArg: 3.022 ± 0.0
3.886AspSer: 3.886 ± 0.0
2.159AspThr: 2.159 ± 0.0
5.181AspVal: 5.181 ± 0.0
0.432AspTrp: 0.432 ± 0.0
1.727AspTyr: 1.727 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
2.159GluAla: 2.159 ± 0.0
2.591GluCys: 2.591 ± 0.0
2.159GluAsp: 2.159 ± 0.0
2.591GluGlu: 2.591 ± 0.0
2.159GluPhe: 2.159 ± 0.0
1.727GluGly: 1.727 ± 0.0
0.864GluHis: 0.864 ± 0.0
3.454GluIle: 3.454 ± 0.0
3.454GluLys: 3.454 ± 0.0
4.75GluLeu: 4.75 ± 0.0
0.864GluMet: 0.864 ± 0.0
1.727GluAsn: 1.727 ± 0.0
2.591GluPro: 2.591 ± 0.0
1.295GluGln: 1.295 ± 0.0
1.295GluArg: 1.295 ± 0.0
2.159GluSer: 2.159 ± 0.0
2.159GluThr: 2.159 ± 0.0
2.591GluVal: 2.591 ± 0.0
0.432GluTrp: 0.432 ± 0.0
1.727GluTyr: 1.727 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
1.295PheAla: 1.295 ± 0.0
0.864PheCys: 0.864 ± 0.0
3.022PheAsp: 3.022 ± 0.0
1.727PheGlu: 1.727 ± 0.0
1.727PhePhe: 1.727 ± 0.0
2.591PheGly: 2.591 ± 0.0
0.864PheHis: 0.864 ± 0.0
1.295PheIle: 1.295 ± 0.0
3.454PheLys: 3.454 ± 0.0
3.454PheLeu: 3.454 ± 0.0
0.864PheMet: 0.864 ± 0.0
4.75PheAsn: 4.75 ± 0.0
0.432PhePro: 0.432 ± 0.0
1.295PheGln: 1.295 ± 0.0
1.727PheArg: 1.727 ± 0.0
5.181PheSer: 5.181 ± 0.0
3.022PheThr: 3.022 ± 0.0
2.159PheVal: 2.159 ± 0.0
0.432PheTrp: 0.432 ± 0.0
3.454PheTyr: 3.454 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
4.318GlyAla: 4.318 ± 0.0
0.864GlyCys: 0.864 ± 0.0
5.181GlyAsp: 5.181 ± 0.0
3.022GlyGlu: 3.022 ± 0.0
3.022GlyPhe: 3.022 ± 0.0
3.022GlyGly: 3.022 ± 0.0
1.295GlyHis: 1.295 ± 0.0
3.886GlyIle: 3.886 ± 0.0
3.454GlyLys: 3.454 ± 0.0
6.908GlyLeu: 6.908 ± 0.0
0.864GlyMet: 0.864 ± 0.0
2.591GlyAsn: 2.591 ± 0.0
2.159GlyPro: 2.159 ± 0.0
1.295GlyGln: 1.295 ± 0.0
2.159GlyArg: 2.159 ± 0.0
5.181GlySer: 5.181 ± 0.0
4.318GlyThr: 4.318 ± 0.0
3.454GlyVal: 3.454 ± 0.0
0.864GlyTrp: 0.864 ± 0.0
4.75GlyTyr: 4.75 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
1.295HisAla: 1.295 ± 0.0
0.432HisCys: 0.432 ± 0.0
1.727HisAsp: 1.727 ± 0.0
1.295HisGlu: 1.295 ± 0.0
1.727HisPhe: 1.727 ± 0.0
1.295HisGly: 1.295 ± 0.0
0.432HisHis: 0.432 ± 0.0
4.75HisIle: 4.75 ± 0.0
0.864HisLys: 0.864 ± 0.0
0.864HisLeu: 0.864 ± 0.0
0.432HisMet: 0.432 ± 0.0
2.159HisAsn: 2.159 ± 0.0
0.864HisPro: 0.864 ± 0.0
1.295HisGln: 1.295 ± 0.0
0.432HisArg: 0.432 ± 0.0
1.295HisSer: 1.295 ± 0.0
1.727HisThr: 1.727 ± 0.0
1.295HisVal: 1.295 ± 0.0
0.0HisTrp: 0.0 ± 0.0
0.864HisTyr: 0.864 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.454IleAla: 3.454 ± 0.0
1.295IleCys: 1.295 ± 0.0
7.34IleAsp: 7.34 ± 0.0
2.159IleGlu: 2.159 ± 0.0
3.886IlePhe: 3.886 ± 0.0
5.613IleGly: 5.613 ± 0.0
0.0IleHis: 0.0 ± 0.0
7.772IleIle: 7.772 ± 0.0
5.613IleLys: 5.613 ± 0.0
6.477IleLeu: 6.477 ± 0.0
0.864IleMet: 0.864 ± 0.0
5.181IleAsn: 5.181 ± 0.0
3.454IlePro: 3.454 ± 0.0
4.318IleGln: 4.318 ± 0.0
3.022IleArg: 3.022 ± 0.0
6.045IleSer: 6.045 ± 0.0
6.045IleThr: 6.045 ± 0.0
3.022IleVal: 3.022 ± 0.0
2.159IleTrp: 2.159 ± 0.0
1.295IleTyr: 1.295 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
3.022LysAla: 3.022 ± 0.0
1.295LysCys: 1.295 ± 0.0
4.318LysAsp: 4.318 ± 0.0
2.159LysGlu: 2.159 ± 0.0
2.159LysPhe: 2.159 ± 0.0
3.022LysGly: 3.022 ± 0.0
0.864LysHis: 0.864 ± 0.0
4.318LysIle: 4.318 ± 0.0
3.022LysLys: 3.022 ± 0.0
3.886LysLeu: 3.886 ± 0.0
1.295LysMet: 1.295 ± 0.0
2.591LysAsn: 2.591 ± 0.0
2.591LysPro: 2.591 ± 0.0
1.295LysGln: 1.295 ± 0.0
2.591LysArg: 2.591 ± 0.0
3.886LysSer: 3.886 ± 0.0
1.295LysThr: 1.295 ± 0.0
5.181LysVal: 5.181 ± 0.0
0.432LysTrp: 0.432 ± 0.0
4.75LysTyr: 4.75 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
6.045LeuAla: 6.045 ± 0.0
1.295LeuCys: 1.295 ± 0.0
4.318LeuAsp: 4.318 ± 0.0
3.454LeuGlu: 3.454 ± 0.0
2.159LeuPhe: 2.159 ± 0.0
3.886LeuGly: 3.886 ± 0.0
3.454LeuHis: 3.454 ± 0.0
5.181LeuIle: 5.181 ± 0.0
5.181LeuLys: 5.181 ± 0.0
4.75LeuLeu: 4.75 ± 0.0
3.454LeuMet: 3.454 ± 0.0
4.75LeuAsn: 4.75 ± 0.0
5.613LeuPro: 5.613 ± 0.0
3.022LeuGln: 3.022 ± 0.0
4.75LeuArg: 4.75 ± 0.0
9.067LeuSer: 9.067 ± 0.0
6.045LeuThr: 6.045 ± 0.0
5.181LeuVal: 5.181 ± 0.0
0.432LeuTrp: 0.432 ± 0.0
1.295LeuTyr: 1.295 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
0.864MetAla: 0.864 ± 0.0
0.864MetCys: 0.864 ± 0.0
0.864MetAsp: 0.864 ± 0.0
0.432MetGlu: 0.432 ± 0.0
0.432MetPhe: 0.432 ± 0.0
1.295MetGly: 1.295 ± 0.0
0.864MetHis: 0.864 ± 0.0
1.295MetIle: 1.295 ± 0.0
0.864MetLys: 0.864 ± 0.0
2.159MetLeu: 2.159 ± 0.0
0.432MetMet: 0.432 ± 0.0
0.0MetAsn: 0.0 ± 0.0
0.864MetPro: 0.864 ± 0.0
0.864MetGln: 0.864 ± 0.0
1.727MetArg: 1.727 ± 0.0
2.591MetSer: 2.591 ± 0.0
2.591MetThr: 2.591 ± 0.0
1.727MetVal: 1.727 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.432MetTyr: 0.432 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.591AsnAla: 2.591 ± 0.0
2.159AsnCys: 2.159 ± 0.0
1.295AsnAsp: 1.295 ± 0.0
5.181AsnGlu: 5.181 ± 0.0
2.591AsnPhe: 2.591 ± 0.0
4.318AsnGly: 4.318 ± 0.0
1.727AsnHis: 1.727 ± 0.0
5.613AsnIle: 5.613 ± 0.0
1.727AsnLys: 1.727 ± 0.0
1.295AsnLeu: 1.295 ± 0.0
0.432AsnMet: 0.432 ± 0.0
3.454AsnAsn: 3.454 ± 0.0
3.886AsnPro: 3.886 ± 0.0
2.591AsnGln: 2.591 ± 0.0
1.295AsnArg: 1.295 ± 0.0
7.772AsnSer: 7.772 ± 0.0
2.591AsnThr: 2.591 ± 0.0
3.886AsnVal: 3.886 ± 0.0
0.432AsnTrp: 0.432 ± 0.0
4.318AsnTyr: 4.318 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
2.159ProAla: 2.159 ± 0.0
0.432ProCys: 0.432 ± 0.0
3.454ProAsp: 3.454 ± 0.0
2.159ProGlu: 2.159 ± 0.0
2.159ProPhe: 2.159 ± 0.0
3.022ProGly: 3.022 ± 0.0
0.432ProHis: 0.432 ± 0.0
3.022ProIle: 3.022 ± 0.0
1.727ProLys: 1.727 ± 0.0
4.318ProLeu: 4.318 ± 0.0
0.432ProMet: 0.432 ± 0.0
2.591ProAsn: 2.591 ± 0.0
0.432ProPro: 0.432 ± 0.0
2.591ProGln: 2.591 ± 0.0
1.727ProArg: 1.727 ± 0.0
3.454ProSer: 3.454 ± 0.0
3.022ProThr: 3.022 ± 0.0
5.613ProVal: 5.613 ± 0.0
1.727ProTrp: 1.727 ± 0.0
0.864ProTyr: 0.864 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
1.295GlnAla: 1.295 ± 0.0
0.864GlnCys: 0.864 ± 0.0
4.318GlnAsp: 4.318 ± 0.0
0.0GlnGlu: 0.0 ± 0.0
0.432GlnPhe: 0.432 ± 0.0
3.886GlnGly: 3.886 ± 0.0
1.727GlnHis: 1.727 ± 0.0
3.886GlnIle: 3.886 ± 0.0
1.295GlnLys: 1.295 ± 0.0
3.022GlnLeu: 3.022 ± 0.0
0.0GlnMet: 0.0 ± 0.0
1.295GlnAsn: 1.295 ± 0.0
1.727GlnPro: 1.727 ± 0.0
0.864GlnGln: 0.864 ± 0.0
0.864GlnArg: 0.864 ± 0.0
2.591GlnSer: 2.591 ± 0.0
0.432GlnThr: 0.432 ± 0.0
1.295GlnVal: 1.295 ± 0.0
0.0GlnTrp: 0.0 ± 0.0
1.295GlnTyr: 1.295 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
2.159ArgAla: 2.159 ± 0.0
0.432ArgCys: 0.432 ± 0.0
5.181ArgAsp: 5.181 ± 0.0
0.432ArgGlu: 0.432 ± 0.0
1.295ArgPhe: 1.295 ± 0.0
3.022ArgGly: 3.022 ± 0.0
1.295ArgHis: 1.295 ± 0.0
3.454ArgIle: 3.454 ± 0.0
2.591ArgLys: 2.591 ± 0.0
3.022ArgLeu: 3.022 ± 0.0
0.432ArgMet: 0.432 ± 0.0
3.454ArgAsn: 3.454 ± 0.0
2.159ArgPro: 2.159 ± 0.0
1.295ArgGln: 1.295 ± 0.0
1.295ArgArg: 1.295 ± 0.0
3.886ArgSer: 3.886 ± 0.0
0.864ArgThr: 0.864 ± 0.0
1.295ArgVal: 1.295 ± 0.0
1.295ArgTrp: 1.295 ± 0.0
4.318ArgTyr: 4.318 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
6.477SerAla: 6.477 ± 0.0
0.864SerCys: 0.864 ± 0.0
3.886SerAsp: 3.886 ± 0.0
3.886SerGlu: 3.886 ± 0.0
5.181SerPhe: 5.181 ± 0.0
4.75SerGly: 4.75 ± 0.0
1.727SerHis: 1.727 ± 0.0
8.636SerIle: 8.636 ± 0.0
3.022SerLys: 3.022 ± 0.0
8.636SerLeu: 8.636 ± 0.0
3.454SerMet: 3.454 ± 0.0
4.75SerAsn: 4.75 ± 0.0
3.022SerPro: 3.022 ± 0.0
2.591SerGln: 2.591 ± 0.0
4.318SerArg: 4.318 ± 0.0
9.931SerSer: 9.931 ± 0.0
2.591SerThr: 2.591 ± 0.0
6.477SerVal: 6.477 ± 0.0
1.295SerTrp: 1.295 ± 0.0
3.454SerTyr: 3.454 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
2.591ThrAla: 2.591 ± 0.0
0.864ThrCys: 0.864 ± 0.0
1.727ThrAsp: 1.727 ± 0.0
3.886ThrGlu: 3.886 ± 0.0
1.727ThrPhe: 1.727 ± 0.0
3.886ThrGly: 3.886 ± 0.0
1.295ThrHis: 1.295 ± 0.0
6.045ThrIle: 6.045 ± 0.0
0.864ThrLys: 0.864 ± 0.0
5.613ThrLeu: 5.613 ± 0.0
2.159ThrMet: 2.159 ± 0.0
3.886ThrAsn: 3.886 ± 0.0
2.591ThrPro: 2.591 ± 0.0
2.159ThrGln: 2.159 ± 0.0
4.318ThrArg: 4.318 ± 0.0
5.181ThrSer: 5.181 ± 0.0
3.886ThrThr: 3.886 ± 0.0
0.864ThrVal: 0.864 ± 0.0
0.0ThrTrp: 0.0 ± 0.0
5.181ThrTyr: 5.181 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
3.022ValAla: 3.022 ± 0.0
1.727ValCys: 1.727 ± 0.0
2.591ValAsp: 2.591 ± 0.0
2.591ValGlu: 2.591 ± 0.0
3.022ValPhe: 3.022 ± 0.0
3.022ValGly: 3.022 ± 0.0
1.295ValHis: 1.295 ± 0.0
3.454ValIle: 3.454 ± 0.0
3.022ValLys: 3.022 ± 0.0
6.908ValLeu: 6.908 ± 0.0
0.432ValMet: 0.432 ± 0.0
4.318ValAsn: 4.318 ± 0.0
4.75ValPro: 4.75 ± 0.0
0.864ValGln: 0.864 ± 0.0
3.022ValArg: 3.022 ± 0.0
4.75ValSer: 4.75 ± 0.0
6.045ValThr: 6.045 ± 0.0
7.34ValVal: 7.34 ± 0.0
0.0ValTrp: 0.0 ± 0.0
1.727ValTyr: 1.727 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
1.295TrpAla: 1.295 ± 0.0
0.432TrpCys: 0.432 ± 0.0
0.864TrpAsp: 0.864 ± 0.0
0.432TrpGlu: 0.432 ± 0.0
0.864TrpPhe: 0.864 ± 0.0
0.0TrpGly: 0.0 ± 0.0
1.295TrpHis: 1.295 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.864TrpLys: 0.864 ± 0.0
0.432TrpLeu: 0.432 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.432TrpPro: 0.432 ± 0.0
0.864TrpGln: 0.864 ± 0.0
1.295TrpArg: 1.295 ± 0.0
1.295TrpSer: 1.295 ± 0.0
0.432TrpThr: 0.432 ± 0.0
0.432TrpVal: 0.432 ± 0.0
0.432TrpTrp: 0.432 ± 0.0
0.864TrpTyr: 0.864 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.159TyrAla: 2.159 ± 0.0
0.864TyrCys: 0.864 ± 0.0
1.727TyrAsp: 1.727 ± 0.0
2.159TyrGlu: 2.159 ± 0.0
1.295TyrPhe: 1.295 ± 0.0
4.318TyrGly: 4.318 ± 0.0
0.432TyrHis: 0.432 ± 0.0
2.159TyrIle: 2.159 ± 0.0
4.318TyrLys: 4.318 ± 0.0
4.318TyrLeu: 4.318 ± 0.0
1.295TyrMet: 1.295 ± 0.0
3.022TyrAsn: 3.022 ± 0.0
2.591TyrPro: 2.591 ± 0.0
0.432TyrGln: 0.432 ± 0.0
2.591TyrArg: 2.591 ± 0.0
4.318TyrSer: 4.318 ± 0.0
3.886TyrThr: 3.886 ± 0.0
3.022TyrVal: 3.022 ± 0.0
0.0TyrTrp: 0.0 ± 0.0
4.318TyrTyr: 4.318 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (2317 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski