Hubei picorna-like virus 45
Average proteome isoelectric point is 5.31
Get precalculated fractions of proteins
Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
All
Note: above files contain also dissociation constants (pKa)
Virtual 2D-PAGE plot for 1 proteins (isoelectric point calculated using IPC2_protein)
Get csv file with sequences according to given criteria:
* You can choose from 21 different methods for calculating isoelectric point
Summary statistics related to proteome-wise predictions
Protein with the lowest isoelectric point:
>tr|A0A1L3KJ54|A0A1L3KJ54_9VIRU RNA-directed RNA polymerase OS=Hubei picorna-like virus 45 OX=1923126 PE=4 SV=1
MM1 pKa = 6.96 STNGKK6 pKa = 8.76 NFSVTRR12 pKa = 11.84 QPPMGQPLEE21 pKa = 4.28 RR22 pKa = 11.84 EE23 pKa = 4.58 AISEE27 pKa = 4.4 SVGTPTHH34 pKa = 6.05 VGISTLMQNWNLHH47 pKa = 4.58 GLKK50 pKa = 9.28 MEE52 pKa = 4.85 PFHH55 pKa = 6.88 DD56 pKa = 3.71 TVKK59 pKa = 10.66 RR60 pKa = 11.84 FVGQGRR66 pKa = 11.84 LPRR69 pKa = 11.84 CGNFSPKK76 pKa = 9.14 MMKK79 pKa = 8.39 ITNKK83 pKa = 10.13 KK84 pKa = 9.61 GEE86 pKa = 4.15 QVDD89 pKa = 5.32 IIDD92 pKa = 3.6 PWSYY96 pKa = 11.54 RR97 pKa = 11.84 DD98 pKa = 3.43 GKK100 pKa = 9.68 HH101 pKa = 4.98 QAEE104 pKa = 4.24 EE105 pKa = 4.02 MAIEE109 pKa = 4.42 TWALYY114 pKa = 7.52 DD115 pKa = 3.36 TRR117 pKa = 11.84 LPNRR121 pKa = 11.84 KK122 pKa = 8.07 FTWAQMEE129 pKa = 4.65 GARR132 pKa = 11.84 MACWFFLKK140 pKa = 10.51 DD141 pKa = 3.27 WIKK144 pKa = 8.56 YY145 pKa = 6.22 TKK147 pKa = 9.88 NASSKK152 pKa = 8.69 RR153 pKa = 11.84 QCIFGTCFMLLCAIEE168 pKa = 5.35 DD169 pKa = 3.83 EE170 pKa = 4.66 TTKK173 pKa = 10.86 KK174 pKa = 10.54 VDD176 pKa = 4.42 AICDD180 pKa = 3.98 KK181 pKa = 9.93 IHH183 pKa = 6.73 RR184 pKa = 11.84 RR185 pKa = 11.84 YY186 pKa = 9.86 GQAPPPSEE194 pKa = 5.02 KK195 pKa = 9.88 ILPAPTPFKK204 pKa = 10.67 LVSQLSVEE212 pKa = 4.18 ALSYY216 pKa = 11.13 ALEE219 pKa = 4.24 EE220 pKa = 4.32 VADD223 pKa = 3.77 IPMEE227 pKa = 3.89 RR228 pKa = 11.84 ARR230 pKa = 11.84 VQKK233 pKa = 11.01 ASVSYY238 pKa = 9.27 EE239 pKa = 4.06 KK240 pKa = 10.58 PLTAQMVTVSPPVFTSKK257 pKa = 10.62 DD258 pKa = 3.61 VPVSTGFSPMDD269 pKa = 3.08 IDD271 pKa = 4.23 AFDD274 pKa = 4.6 RR275 pKa = 11.84 EE276 pKa = 4.55 VAANLAEE283 pKa = 4.31 VSDD286 pKa = 3.91 LFKK289 pKa = 10.92 NLKK292 pKa = 8.19 EE293 pKa = 3.97 HH294 pKa = 6.95 EE295 pKa = 4.2 EE296 pKa = 4.27 MIGSGEE302 pKa = 4.15 VEE304 pKa = 4.19 EE305 pKa = 4.42 EE306 pKa = 3.9 EE307 pKa = 4.09 PMEE310 pKa = 4.1 VEE312 pKa = 4.11 EE313 pKa = 4.83 IKK315 pKa = 10.5 PIEE318 pKa = 4.02 MNPYY322 pKa = 7.89 QWEE325 pKa = 4.13 FSHH328 pKa = 6.16 YY329 pKa = 10.77 LKK331 pKa = 10.84 LKK333 pKa = 8.09 SQAVIEE339 pKa = 4.33 AQLLLQKK346 pKa = 10.3 VDD348 pKa = 4.33 PLNLTCKK355 pKa = 9.94 CWNCVEE361 pKa = 4.08 RR362 pKa = 11.84 FLRR365 pKa = 11.84 RR366 pKa = 11.84 NPYY369 pKa = 10.2 ALHH372 pKa = 5.73 NQINVCPDD380 pKa = 2.69 QCLYY384 pKa = 11.14 TNDD387 pKa = 4.11 FVDD390 pKa = 3.15 KK391 pKa = 10.34 TEE393 pKa = 4.07 RR394 pKa = 11.84 ARR396 pKa = 11.84 LAHH399 pKa = 7.39 RR400 pKa = 11.84 ARR402 pKa = 11.84 CLEE405 pKa = 3.92 VLTGRR410 pKa = 11.84 VSEE413 pKa = 4.31 YY414 pKa = 10.8 QMCSHH419 pKa = 6.75 EE420 pKa = 4.4 VVDD423 pKa = 3.89 WANTEE428 pKa = 3.95 SQEE431 pKa = 4.47 FFDD434 pKa = 5.82 EE435 pKa = 4.78 EE436 pKa = 4.82 YY437 pKa = 11.07 EE438 pKa = 5.38 DD439 pKa = 3.63 MAQIQGSEE447 pKa = 4.25 EE448 pKa = 4.37 CVSLDD453 pKa = 4.97 DD454 pKa = 5.62 LDD456 pKa = 6.17 LNTFMCEE463 pKa = 3.46 IEE465 pKa = 4.76 LDD467 pKa = 3.92 YY468 pKa = 11.45 FMEE471 pKa = 4.41 QAGAPDD477 pKa = 4.02 WRR479 pKa = 11.84 ILWVTDD485 pKa = 3.48 EE486 pKa = 4.6 EE487 pKa = 4.3 PWSIFEE493 pKa = 4.69 QEE495 pKa = 4.5 EE496 pKa = 4.07 LHH498 pKa = 6.68 QLYY501 pKa = 10.45 LQMLEE506 pKa = 4.74 DD507 pKa = 4.18 EE508 pKa = 4.73 SEE510 pKa = 4.35 EE511 pKa = 4.5 LPFAQMDD518 pKa = 3.7 EE519 pKa = 4.44 CLEE522 pKa = 4.05 SHH524 pKa = 6.61 EE525 pKa = 4.95 SVEE528 pKa = 4.2 KK529 pKa = 9.18 TQNLTFVDD537 pKa = 4.2 EE538 pKa = 4.78 RR539 pKa = 11.84 PVDD542 pKa = 3.35 RR543 pKa = 11.84 AGAYY547 pKa = 9.8 LGSSSRR553 pKa = 11.84 TYY555 pKa = 10.71 DD556 pKa = 2.93 INRR559 pKa = 11.84 SIAEE563 pKa = 4.33 KK564 pKa = 9.95 PWTLNATLDD573 pKa = 3.59 RR574 pKa = 11.84 EE575 pKa = 4.32 IPVAEE580 pKa = 4.74 FEE582 pKa = 4.58 WNTQGVFTNLVEE594 pKa = 4.98 LPFPKK599 pKa = 10.33 CYY601 pKa = 9.44 TDD603 pKa = 3.69 KK604 pKa = 10.63 SANMGRR610 pKa = 11.84 NIVKK614 pKa = 10.08 NFGFLRR620 pKa = 11.84 SDD622 pKa = 3.14 AYY624 pKa = 10.82 FRR626 pKa = 11.84 IQLNGNRR633 pKa = 11.84 FDD635 pKa = 4.34 QGRR638 pKa = 11.84 LVCWLRR644 pKa = 11.84 PLTWSVDD651 pKa = 3.54 KK652 pKa = 11.17 KK653 pKa = 10.79 RR654 pKa = 11.84 LSPSNFANLAHH665 pKa = 6.3 VFLDD669 pKa = 3.54 ASVSNSGVLTMPYY682 pKa = 8.84 THH684 pKa = 7.11 MLTHH688 pKa = 6.67 FCIKK692 pKa = 9.9 PKK694 pKa = 10.5 KK695 pKa = 10.57 LEE697 pKa = 4.58 DD698 pKa = 4.01 DD699 pKa = 4.43 SMSCLCTLVITVLNKK714 pKa = 10.2 LRR716 pKa = 11.84 VGEE719 pKa = 4.3 GAPPTLFGTVYY730 pKa = 10.94 AKK732 pKa = 10.75 LDD734 pKa = 3.79 NPVLHH739 pKa = 5.45 QVCYY743 pKa = 10.2 TSDD746 pKa = 3.02 TMSFDD751 pKa = 3.24 STTGYY756 pKa = 10.73 VDD758 pKa = 4.98 SLDD761 pKa = 4.05 NPNAPAIIQGEE772 pKa = 3.94 PGIWEE777 pKa = 3.91 KK778 pKa = 10.96 AAATGVGQALGNVLKK793 pKa = 11.18 LMTGGLATGVGNFLGGLIFDD813 pKa = 4.63 RR814 pKa = 11.84 PIDD817 pKa = 3.97 PRR819 pKa = 11.84 PVEE822 pKa = 3.91 PVLNRR827 pKa = 11.84 SVQPMCYY834 pKa = 9.87 AVGPDD839 pKa = 3.03 SSVRR843 pKa = 11.84 MGMTPISQRR852 pKa = 11.84 EE853 pKa = 3.95 SRR855 pKa = 11.84 PAMVASNFDD864 pKa = 3.63 DD865 pKa = 3.73 MNFDD869 pKa = 5.67 KK870 pKa = 10.77 ILQTYY875 pKa = 8.42 QLLYY879 pKa = 10.13 SDD881 pKa = 5.5 SISTSTSVKK890 pKa = 10.29 SRR892 pKa = 11.84 VARR895 pKa = 11.84 LPVCPTFIPSTDD907 pKa = 3.19 INNLSTTGVRR917 pKa = 11.84 YY918 pKa = 9.82 RR919 pKa = 11.84 PTALAYY925 pKa = 9.6 ISRR928 pKa = 11.84 AFAYY932 pKa = 10.71 YY933 pKa = 10.21 EE934 pKa = 4.14 GSLVFKK940 pKa = 9.95 FQFVTSQFHH949 pKa = 5.55 SMRR952 pKa = 11.84 IGIAFDD958 pKa = 3.92 PLDD961 pKa = 4.65 DD962 pKa = 3.88 FTEE965 pKa = 4.91 EE966 pKa = 3.55 ISYY969 pKa = 9.89 EE970 pKa = 4.08 QIFNMNMGLFDD981 pKa = 3.4 IQEE984 pKa = 3.93 QKK986 pKa = 10.7 EE987 pKa = 4.19 IEE989 pKa = 4.67 FVCPMTSTRR998 pKa = 11.84 SWLRR1002 pKa = 11.84 CDD1004 pKa = 4.42 RR1005 pKa = 11.84 FRR1007 pKa = 11.84 SDD1009 pKa = 4.27 ANFSGAGAEE1018 pKa = 4.09 EE1019 pKa = 4.72 LNRR1022 pKa = 11.84 EE1023 pKa = 4.05 PLNRR1027 pKa = 11.84 SSMGSLSMWIVNRR1040 pKa = 11.84 LVAPEE1045 pKa = 4.39 NVSQTIDD1052 pKa = 3.34 FNIFIKK1058 pKa = 10.51 AGKK1061 pKa = 9.48 DD1062 pKa = 3.12 FRR1064 pKa = 11.84 LAIPVPLHH1072 pKa = 6.0 PLRR1075 pKa = 11.84 LTPAVDD1081 pKa = 3.81 TFAQIPDD1088 pKa = 3.63 SQYY1091 pKa = 10.97 VFAPNCPPNLIGSPGMFEE1109 pKa = 3.46 NKK1111 pKa = 10.26 AYY1113 pKa = 9.72 IEE1115 pKa = 3.79 YY1116 pKa = 9.73 LYY1118 pKa = 10.8 RR1119 pKa = 11.84 VGRR1122 pKa = 11.84 QFYY1125 pKa = 11.18 LEE1127 pKa = 4.28 GKK1129 pKa = 8.41 LTIPTDD1135 pKa = 4.44 GYY1137 pKa = 9.83 WWQCVPNLQLGYY1149 pKa = 10.66 VDD1151 pKa = 6.3 DD1152 pKa = 4.11 VLAWRR1157 pKa = 11.84 DD1158 pKa = 3.57 KK1159 pKa = 11.35 ASLLSTYY1166 pKa = 10.84 TNDD1169 pKa = 3.52 TPQWQYY1175 pKa = 10.12 MASLLPYY1182 pKa = 8.12 VNKK1185 pKa = 9.59 WRR1187 pKa = 11.84 IPTDD1191 pKa = 3.02 DD1192 pKa = 3.11 WAKK1195 pKa = 10.75 PKK1197 pKa = 10.91 DD1198 pKa = 3.81 SDD1200 pKa = 3.85 SFKK1203 pKa = 10.83 YY1204 pKa = 10.77 LKK1206 pKa = 10.47 DD1207 pKa = 3.61 DD1208 pKa = 3.73 GAIVQGSVEE1217 pKa = 4.13 VATTSRR1223 pKa = 11.84 EE1224 pKa = 3.89 QGAEE1228 pKa = 4.08 PIVPTRR1234 pKa = 11.84 GMQTAEE1240 pKa = 4.17 AAPTTISEE1248 pKa = 4.23 NAQNLQTVMRR1258 pKa = 11.84 RR1259 pKa = 11.84 YY1260 pKa = 8.78 YY1261 pKa = 9.74 PLYY1264 pKa = 9.81 EE1265 pKa = 4.34 SEE1267 pKa = 4.99 PIYY1270 pKa = 11.09 NSLGYY1275 pKa = 8.4 TLITVPVTPTCLTAEE1290 pKa = 4.79 FKK1292 pKa = 10.31 PYY1294 pKa = 9.63 KK1295 pKa = 9.89 GKK1297 pKa = 11.17 VMFNRR1302 pKa = 11.84 ILHH1305 pKa = 6.39 PIAYY1309 pKa = 9.6 FSRR1312 pKa = 11.84 LFNYY1316 pKa = 8.05 WAGSLSYY1323 pKa = 10.49 RR1324 pKa = 11.84 IIVKK1328 pKa = 9.58 SRR1330 pKa = 11.84 KK1331 pKa = 7.18 TSRR1334 pKa = 11.84 KK1335 pKa = 8.91 VYY1337 pKa = 10.38 AIYY1340 pKa = 10.4 DD1341 pKa = 3.42 PRR1343 pKa = 11.84 TTVNFRR1349 pKa = 11.84 VLSGIMFDD1357 pKa = 3.81 RR1358 pKa = 11.84 LSHH1361 pKa = 6.22 RR1362 pKa = 11.84 MNLATVLSVSHH1373 pKa = 6.08 LQGSVDD1379 pKa = 3.68 VQVPWSSRR1387 pKa = 11.84 YY1388 pKa = 9.33 DD1389 pKa = 3.22 QGLIEE1394 pKa = 5.41 LDD1396 pKa = 3.92 EE1397 pKa = 4.96 DD1398 pKa = 3.99 LQDD1401 pKa = 4.69 LRR1403 pKa = 11.84 SQNGTLEE1410 pKa = 4.01 IYY1412 pKa = 10.29 IEE1414 pKa = 4.41 NDD1416 pKa = 2.64 TDD1418 pKa = 4.16 LEE1420 pKa = 4.39 PFGTDD1425 pKa = 2.93 PFTVSVFLSTGDD1437 pKa = 3.87 DD1438 pKa = 3.67 FVLNLYY1444 pKa = 10.18 RR1445 pKa = 11.84 GPTYY1449 pKa = 10.01 IYY1451 pKa = 9.21 EE1452 pKa = 4.53 CKK1454 pKa = 10.5 YY1455 pKa = 9.59 LTNSYY1460 pKa = 10.66 SGAKK1464 pKa = 9.27 SMCVKK1469 pKa = 10.62 YY1470 pKa = 10.78 PEE1472 pKa = 4.02 FQYY1475 pKa = 11.5 NNSIRR1480 pKa = 11.84 DD1481 pKa = 3.46 WGNYY1485 pKa = 7.02 PATNLGRR1492 pKa = 11.84 PQWPRR1497 pKa = 11.84 PGGVYY1502 pKa = 10.65 NFGTTEE1508 pKa = 3.99 VQSNCDD1514 pKa = 3.49 PLTPKK1519 pKa = 10.42 SFQEE1523 pKa = 3.71 IVKK1526 pKa = 10.14 RR1527 pKa = 11.84 KK1528 pKa = 9.61 AGAFGKK1534 pKa = 9.34 SVKK1537 pKa = 10.37 GPSALFCPPPTITEE1551 pKa = 4.14 GNEE1554 pKa = 3.59 IQHH1557 pKa = 6.3 FEE1559 pKa = 4.09 EE1560 pKa = 4.81 LLEE1563 pKa = 4.53 GTDD1566 pKa = 3.64 GAVIQGLFADD1576 pKa = 4.26 LRR1578 pKa = 11.84 KK1579 pKa = 9.51 MKK1581 pKa = 10.84 NNVVDD1586 pKa = 3.96 SSTALKK1592 pKa = 10.76 NILTRR1597 pKa = 11.84 VDD1599 pKa = 3.55 EE1600 pKa = 4.66 TNLSEE1605 pKa = 5.92 GIACLVQKK1613 pKa = 11.08 ANAFTNGISEE1623 pKa = 4.6 SVSTPAVAASVAKK1636 pKa = 10.58 YY1637 pKa = 10.16 SVLSAEE1643 pKa = 4.28 ILTVGAFIYY1652 pKa = 10.23 SLKK1655 pKa = 10.8 EE1656 pKa = 3.75 CFQNPNLKK1664 pKa = 10.16 NFIMLSITAAGCIGFAVSNALQSVITNVVNWALSCEE1700 pKa = 4.29 LPQTQALDD1708 pKa = 3.4 GATAQVIDD1716 pKa = 3.98 SHH1718 pKa = 8.33 SSTICTVVAVIATVFYY1734 pKa = 10.64 AYY1736 pKa = 9.68 IFDD1739 pKa = 4.34 VLPSMTTLKK1748 pKa = 10.8 EE1749 pKa = 4.0 GFRR1752 pKa = 11.84 KK1753 pKa = 10.26 LFGDD1757 pKa = 5.98 DD1758 pKa = 2.84 IDD1760 pKa = 4.95 LPKK1763 pKa = 10.42 KK1764 pKa = 10.26 PKK1766 pKa = 10.66 AKK1768 pKa = 9.75 IQAKK1772 pKa = 9.99 GFEE1775 pKa = 4.63 LKK1777 pKa = 10.21 NAHH1780 pKa = 6.55 FSLLGITALDD1790 pKa = 3.53 KK1791 pKa = 11.37 VYY1793 pKa = 10.34 TKK1795 pKa = 10.7 CLDD1798 pKa = 3.6 MVSSFLDD1805 pKa = 3.78 WILEE1809 pKa = 3.81 RR1810 pKa = 11.84 DD1811 pKa = 3.77 NPGVIAARR1819 pKa = 11.84 TTQEE1823 pKa = 3.43 YY1824 pKa = 9.92 RR1825 pKa = 11.84 DD1826 pKa = 4.06 RR1827 pKa = 11.84 IMHH1830 pKa = 6.27 CVNEE1834 pKa = 4.7 LDD1836 pKa = 4.68 LLDD1839 pKa = 3.96 NEE1841 pKa = 5.26 EE1842 pKa = 4.43 YY1843 pKa = 9.03 FTNAMHH1849 pKa = 7.83 DD1850 pKa = 3.8 PFIHH1854 pKa = 5.5 NRR1856 pKa = 11.84 FYY1858 pKa = 11.58 KK1859 pKa = 10.64 LQGEE1863 pKa = 4.48 LNDD1866 pKa = 3.98 LTSLSLRR1873 pKa = 11.84 EE1874 pKa = 4.24 KK1875 pKa = 10.72 KK1876 pKa = 10.25 EE1877 pKa = 3.93 VMDD1880 pKa = 3.73 SQVRR1884 pKa = 11.84 NLISEE1889 pKa = 4.2 CRR1891 pKa = 11.84 KK1892 pKa = 9.89 RR1893 pKa = 11.84 CQKK1896 pKa = 10.41 LIKK1899 pKa = 9.82 EE1900 pKa = 4.69 LEE1902 pKa = 4.16 RR1903 pKa = 11.84 DD1904 pKa = 3.49 SPKK1907 pKa = 10.83 PMLRR1911 pKa = 11.84 YY1912 pKa = 10.08 DD1913 pKa = 4.77 PICICLCGEE1922 pKa = 4.19 SGTGKK1927 pKa = 8.49 TKK1929 pKa = 10.55 LMHH1932 pKa = 7.01 KK1933 pKa = 9.68 IADD1936 pKa = 4.04 VIKK1939 pKa = 10.68 EE1940 pKa = 4.03 EE1941 pKa = 4.13 MDD1943 pKa = 3.43 LPRR1946 pKa = 11.84 YY1947 pKa = 9.27 NLIYY1951 pKa = 10.19 PKK1953 pKa = 10.42 GIKK1956 pKa = 10.14 DD1957 pKa = 4.05 EE1958 pKa = 4.4 FWSGYY1963 pKa = 9.2 KK1964 pKa = 9.65 NQPIVFWDD1972 pKa = 3.79 EE1973 pKa = 3.85 FAQSRR1978 pKa = 11.84 KK1979 pKa = 7.3 MDD1981 pKa = 3.59 EE1982 pKa = 4.43 VIPEE1986 pKa = 4.21 FMTLRR1991 pKa = 11.84 GSTPVMLNMAALNDD2005 pKa = 3.42 KK2006 pKa = 10.68 GKK2008 pKa = 10.51 YY2009 pKa = 6.7 FTSQAMVLTTNVPFEE2024 pKa = 4.72 DD2025 pKa = 4.62 FNAVRR2030 pKa = 11.84 DD2031 pKa = 3.85 NNAFKK2036 pKa = 10.68 RR2037 pKa = 11.84 RR2038 pKa = 11.84 RR2039 pKa = 11.84 HH2040 pKa = 5.42 LLIKK2044 pKa = 9.41 LTHH2047 pKa = 6.31 RR2048 pKa = 11.84 PGFNAMNMQNARR2060 pKa = 11.84 HH2061 pKa = 5.9 DD2062 pKa = 3.59 QFPNWEE2068 pKa = 4.18 HH2069 pKa = 7.33 CFFTLMNPMQDD2080 pKa = 2.99 TAIADD2085 pKa = 4.05 GLDD2088 pKa = 3.17 LTTILEE2094 pKa = 4.35 MVRR2097 pKa = 11.84 LRR2099 pKa = 11.84 VRR2101 pKa = 11.84 RR2102 pKa = 11.84 WHH2104 pKa = 5.39 QNQMAILGAEE2114 pKa = 4.63 DD2115 pKa = 4.93 LPQEE2119 pKa = 4.31 MPRR2122 pKa = 11.84 GIVPIDD2128 pKa = 3.34 NNDD2131 pKa = 3.36 NLNYY2135 pKa = 10.72 DD2136 pKa = 3.79 EE2137 pKa = 5.49 ALEE2140 pKa = 4.08 TLALAEE2146 pKa = 3.99 QAAFEE2151 pKa = 4.78 AIEE2154 pKa = 4.2 EE2155 pKa = 4.17 EE2156 pKa = 4.23 HH2157 pKa = 7.54 LEE2159 pKa = 4.69 AEE2161 pKa = 4.5 NEE2163 pKa = 3.86 FHH2165 pKa = 7.08 NPVNIQQDD2173 pKa = 2.91 IAMNLDD2179 pKa = 3.46 GVPRR2183 pKa = 11.84 EE2184 pKa = 4.15 AFEE2187 pKa = 4.95 ALPEE2191 pKa = 4.22 YY2192 pKa = 10.15 YY2193 pKa = 9.93 RR2194 pKa = 11.84 PPPEE2198 pKa = 3.87 VGPIVDD2204 pKa = 3.8 VEE2206 pKa = 4.38 GAGARR2211 pKa = 11.84 IQMMVEE2217 pKa = 4.06 DD2218 pKa = 4.37 EE2219 pKa = 5.14 DD2220 pKa = 5.22 EE2221 pKa = 4.49 IFVDD2225 pKa = 4.41 CQEE2228 pKa = 4.36 SPFGFVDD2235 pKa = 3.56 YY2236 pKa = 10.99 VRR2238 pKa = 11.84 EE2239 pKa = 3.8 EE2240 pKa = 4.3 RR2241 pKa = 11.84 EE2242 pKa = 3.95 FVTEE2246 pKa = 3.95 CVYY2249 pKa = 11.2 AKK2251 pKa = 10.17 QPVMSVYY2258 pKa = 9.76 PWTAEE2263 pKa = 4.08 EE2264 pKa = 4.07 IKK2266 pKa = 10.74 KK2267 pKa = 10.39 VATKK2271 pKa = 8.34 TKK2273 pKa = 10.28 CRR2275 pKa = 11.84 LFRR2278 pKa = 11.84 LAEE2281 pKa = 4.36 DD2282 pKa = 3.85 CSEE2285 pKa = 4.29 QIALAARR2292 pKa = 11.84 SFLRR2296 pKa = 11.84 SQYY2299 pKa = 8.41 TQSLINKK2306 pKa = 7.76 VRR2308 pKa = 11.84 TNNLWIKK2315 pKa = 9.75 AQNFCSEE2322 pKa = 4.72 LKK2324 pKa = 10.02 QDD2326 pKa = 6.13 LIMCFDD2332 pKa = 4.88 KK2333 pKa = 10.72 IKK2335 pKa = 9.88 KK2336 pKa = 8.14 TIYY2339 pKa = 11.06 DD2340 pKa = 3.78 MIEE2343 pKa = 3.59 NHH2345 pKa = 5.98 PRR2347 pKa = 11.84 IAKK2350 pKa = 9.65 VVGAMTLFAGVGGVLYY2366 pKa = 10.83 AFGNTQSVPIQEE2378 pKa = 4.0 EE2379 pKa = 4.58 GFYY2382 pKa = 10.31 EE2383 pKa = 4.04 SHH2385 pKa = 6.89 IPRR2388 pKa = 11.84 MCRR2391 pKa = 11.84 PRR2393 pKa = 11.84 IIPEE2397 pKa = 4.06 SYY2399 pKa = 9.89 EE2400 pKa = 4.1 AGPDD2404 pKa = 2.82 RR2405 pKa = 11.84 AARR2408 pKa = 11.84 PRR2410 pKa = 11.84 IIPEE2414 pKa = 3.85 SCVDD2418 pKa = 3.66 CEE2420 pKa = 4.18 GAYY2423 pKa = 10.14 EE2424 pKa = 4.38 GGPARR2429 pKa = 11.84 CARR2432 pKa = 11.84 WRR2434 pKa = 11.84 VVPEE2438 pKa = 4.04 GAACQGCEE2446 pKa = 4.88 DD2447 pKa = 4.61 KK2448 pKa = 11.02 PAMDD2452 pKa = 3.77 IRR2454 pKa = 11.84 AKK2456 pKa = 10.12 VHH2458 pKa = 5.94 PAVCRR2463 pKa = 11.84 IRR2465 pKa = 11.84 WDD2467 pKa = 3.47 TTADD2471 pKa = 3.43 GGVGQLNCTRR2481 pKa = 11.84 IGGSLILLPYY2491 pKa = 10.35 HH2492 pKa = 6.2 FFRR2495 pKa = 11.84 YY2496 pKa = 9.65 RR2497 pKa = 11.84 KK2498 pKa = 8.08 TGDD2501 pKa = 3.1 KK2502 pKa = 10.59 FSILHH2507 pKa = 6.54 RR2508 pKa = 11.84 MTTLIYY2514 pKa = 10.14 EE2515 pKa = 4.22 YY2516 pKa = 10.44 DD2517 pKa = 3.77 EE2518 pKa = 4.22 KK2519 pKa = 11.58 RR2520 pKa = 11.84 MFRR2523 pKa = 11.84 EE2524 pKa = 4.49 GAKK2527 pKa = 10.46 DD2528 pKa = 3.04 WVLYY2532 pKa = 10.72 DD2533 pKa = 3.42 LGFRR2537 pKa = 11.84 IEE2539 pKa = 4.07 PAKK2542 pKa = 10.77 HH2543 pKa = 4.85 LFKK2546 pKa = 11.3 YY2547 pKa = 9.82 FVSEE2551 pKa = 3.97 KK2552 pKa = 10.9 NLVRR2556 pKa = 11.84 KK2557 pKa = 10.11 CNAILLAADD2566 pKa = 3.32 VDD2568 pKa = 4.41 GTLKK2572 pKa = 8.39 MTSGKK2577 pKa = 8.95 ATGDD2581 pKa = 3.17 AFFQYY2586 pKa = 10.67 TDD2588 pKa = 4.17 LKK2590 pKa = 10.88 GDD2592 pKa = 3.67 TYY2594 pKa = 10.93 KK2595 pKa = 10.73 QRR2597 pKa = 11.84 GWRR2600 pKa = 11.84 IEE2602 pKa = 3.92 MTTVQGDD2609 pKa = 3.75 CGGLLMGLGAHH2620 pKa = 7.08 LPPPGKK2626 pKa = 9.88 ILGIHH2631 pKa = 5.25 VAGYY2635 pKa = 8.67 HH2636 pKa = 5.58 NKK2638 pKa = 10.48 AIGYY2642 pKa = 8.28 DD2643 pKa = 3.53 VLITRR2648 pKa = 11.84 EE2649 pKa = 4.02 QLEE2652 pKa = 4.38 SLASKK2657 pKa = 10.79 AGILFNEE2664 pKa = 4.34 SPIPKK2669 pKa = 8.5 STDD2672 pKa = 2.53 VTAPLNTFRR2681 pKa = 11.84 LVPHH2685 pKa = 7.05 GDD2687 pKa = 3.39 FTIVGTMDD2695 pKa = 2.62 KK2696 pKa = 9.68 TKK2698 pKa = 10.72 RR2699 pKa = 11.84 VFQPMSSDD2707 pKa = 3.95 LKK2709 pKa = 8.16 PTPWANEE2716 pKa = 3.51 ITDD2719 pKa = 3.92 FPNPKK2724 pKa = 9.75 KK2725 pKa = 9.62 PAHH2728 pKa = 6.12 LMPFKK2733 pKa = 10.79 NADD2736 pKa = 3.47 GNRR2739 pKa = 11.84 ISPLALALPKK2749 pKa = 10.09 YY2750 pKa = 10.32 GKK2752 pKa = 10.35 VSLPLPVRR2760 pKa = 11.84 SIDD2763 pKa = 3.78 KK2764 pKa = 10.34 IVSFLSDD2771 pKa = 3.54 YY2772 pKa = 11.24 LEE2774 pKa = 4.16 SHH2776 pKa = 5.94 LTEE2779 pKa = 4.13 HH2780 pKa = 5.66 TGKK2783 pKa = 10.78 RR2784 pKa = 11.84 IFSDD2788 pKa = 4.04 LEE2790 pKa = 3.95 AVNGIVGVEE2799 pKa = 3.8 YY2800 pKa = 11.01 AEE2802 pKa = 4.11 RR2803 pKa = 11.84 LNMKK2807 pKa = 10.0 SSPGWPYY2814 pKa = 10.2 QIEE2817 pKa = 4.3 NRR2819 pKa = 11.84 GEE2821 pKa = 3.62 PGKK2824 pKa = 10.57 FHH2826 pKa = 7.32 FFDD2829 pKa = 4.18 EE2830 pKa = 5.15 DD2831 pKa = 3.48 GHH2833 pKa = 8.64 IIDD2836 pKa = 4.88 EE2837 pKa = 4.26 KK2838 pKa = 9.97 LQRR2841 pKa = 11.84 RR2842 pKa = 11.84 LDD2844 pKa = 3.67 YY2845 pKa = 10.92 RR2846 pKa = 11.84 IDD2848 pKa = 3.36 EE2849 pKa = 4.33 ARR2851 pKa = 11.84 EE2852 pKa = 3.88 GRR2854 pKa = 11.84 RR2855 pKa = 11.84 VASLWRR2861 pKa = 11.84 DD2862 pKa = 3.49 CLKK2865 pKa = 11.18 DD2866 pKa = 3.38 EE2867 pKa = 4.88 LRR2869 pKa = 11.84 PIEE2872 pKa = 5.27 KK2873 pKa = 9.8 VDD2875 pKa = 3.34 QGKK2878 pKa = 7.76 TRR2880 pKa = 11.84 LFTIAPLDD2888 pKa = 3.4 FTIAVRR2894 pKa = 11.84 KK2895 pKa = 9.7 YY2896 pKa = 10.2 FFDD2899 pKa = 4.11 FVIAFYY2905 pKa = 10.8 SAARR2909 pKa = 11.84 SDD2911 pKa = 3.68 FFSAVGIDD2919 pKa = 4.02 PEE2921 pKa = 4.34 SLDD2924 pKa = 3.1 WTFLYY2929 pKa = 10.77 NRR2931 pKa = 11.84 LRR2933 pKa = 11.84 EE2934 pKa = 4.04 ISDD2937 pKa = 3.34 NAVAGDD2943 pKa = 3.62 YY2944 pKa = 11.15 SGFDD2948 pKa = 3.19 GGLKK2952 pKa = 10.3 PEE2954 pKa = 5.0 AIEE2957 pKa = 5.4 AICKK2961 pKa = 10.1 LINLWYY2967 pKa = 10.21 NDD2969 pKa = 3.4 SPEE2972 pKa = 4.15 NQNVRR2977 pKa = 11.84 RR2978 pKa = 11.84 VLFLEE2983 pKa = 4.54 MCHH2986 pKa = 5.85 TLHH2989 pKa = 7.03 LVNDD2993 pKa = 4.64 CVYY2996 pKa = 10.32 MSHH2999 pKa = 6.51 QGNKK3003 pKa = 9.65 SGNPLTVIINTLANLIYY3020 pKa = 10.31 LLCAWIDD3027 pKa = 3.47 IYY3029 pKa = 10.54 PDD3031 pKa = 3.28 RR3032 pKa = 11.84 PIEE3035 pKa = 5.25 EE3036 pKa = 3.97 FFKK3039 pKa = 9.37 WCRR3042 pKa = 11.84 AIIYY3046 pKa = 10.53 GDD3048 pKa = 3.92 DD3049 pKa = 3.72 LLITVSDD3056 pKa = 3.79 KK3057 pKa = 9.82 VTKK3060 pKa = 10.53 FNQKK3064 pKa = 7.77 TLTASLAKK3072 pKa = 10.32 FGIVFTNEE3080 pKa = 3.73 MKK3082 pKa = 10.68 DD3083 pKa = 3.56 DD3084 pKa = 3.99 SDD3086 pKa = 3.76 VGEE3089 pKa = 4.32 FRR3091 pKa = 11.84 SLDD3094 pKa = 3.18 EE3095 pKa = 3.89 VTFLKK3100 pKa = 10.56 RR3101 pKa = 11.84 GFRR3104 pKa = 11.84 KK3105 pKa = 10.41 DD3106 pKa = 3.42 PEE3108 pKa = 4.27 VGHH3111 pKa = 7.12 LFTLPVMSEE3120 pKa = 4.18 EE3121 pKa = 4.28 TLHH3124 pKa = 7.31 SYY3126 pKa = 9.68 LFWYY3130 pKa = 9.97 RR3131 pKa = 11.84 ATEE3134 pKa = 4.1 EE3135 pKa = 4.04 EE3136 pKa = 4.94 DD3137 pKa = 3.91 EE3138 pKa = 4.3 EE3139 pKa = 4.37 QLRR3142 pKa = 11.84 QNMRR3146 pKa = 11.84 AALNFAFFRR3155 pKa = 11.84 GRR3157 pKa = 11.84 TFYY3160 pKa = 10.75 EE3161 pKa = 4.33 WYY3163 pKa = 9.46 NKK3165 pKa = 8.68 LWKK3168 pKa = 10.29 EE3169 pKa = 4.22 CMRR3172 pKa = 11.84 KK3173 pKa = 9.67 HH3174 pKa = 5.8 GFNPLSISYY3183 pKa = 10.23 DD3184 pKa = 3.49 EE3185 pKa = 4.38 QLDD3188 pKa = 3.51 IFLNKK3193 pKa = 10.08 AGALGEE3199 pKa = 4.01 IAPAQVQGLDD3209 pKa = 3.35 AFMKK3213 pKa = 10.58 ASNNKK3218 pKa = 7.34 WSRR3221 pKa = 11.84 RR3222 pKa = 11.84 FCGVTEE3228 pKa = 4.48 SIFYY3232 pKa = 8.11 YY3233 pKa = 10.61 LCAGLNVFKK3242 pKa = 10.67 CKK3244 pKa = 9.59 NLKK3247 pKa = 9.87 PPSDD3251 pKa = 4.17 DD3252 pKa = 2.83 RR3253 pKa = 11.84 WAVSIPSGEE3262 pKa = 4.4 GKK3264 pKa = 8.38 STLCKK3269 pKa = 9.18 MYY3271 pKa = 9.16 PHH3273 pKa = 7.16 IFVDD3277 pKa = 3.73 HH3278 pKa = 7.75 DD3279 pKa = 3.86 EE3280 pKa = 4.32 LLLPKK3285 pKa = 10.03 FQEE3288 pKa = 3.53 ISKK3291 pKa = 10.49 FNLSKK3296 pKa = 10.99 LPWRR3300 pKa = 11.84 AKK3302 pKa = 8.88 IARR3305 pKa = 11.84 EE3306 pKa = 3.48 IDD3308 pKa = 3.7 FPPEE3312 pKa = 3.49 DD3313 pKa = 3.58 RR3314 pKa = 11.84 RR3315 pKa = 11.84 ILLVHH3320 pKa = 6.49 SPANTKK3326 pKa = 10.5 RR3327 pKa = 11.84 NLIGCFVTPSPTYY3340 pKa = 8.43 IRR3342 pKa = 11.84 VNIFHH3347 pKa = 7.69 RR3348 pKa = 11.84 LLQNEE3353 pKa = 4.78 PYY3355 pKa = 11.34 VMDD3358 pKa = 4.33 FSEE3361 pKa = 5.89 RR3362 pKa = 11.84 NDD3364 pKa = 3.48 TLLRR3368 pKa = 11.84 LARR3371 pKa = 11.84 KK3372 pKa = 9.5 VEE3374 pKa = 4.29 PGLFEE3379 pKa = 6.26 ADD3381 pKa = 3.14
Molecular weight: 384.67 kDa
Isoelectric point according different methods:
IPC2.protein.svr19 5.307
IPC2_protein 5.359
IPC_protein 5.372
Toseland 5.461
ProMoST 5.563
Dawson 5.448
Bjellqvist 5.537
Wikipedia 5.359
Rodwell 5.385
Grimsley 5.448
Solomon 5.448
Lehninger 5.423
Nozaki 5.614
DTASelect 5.779
Thurlkill 5.55
EMBOSS 5.512
Sillero 5.703
Patrickios 4.024
IPC_peptide 5.461
IPC2_peptide 5.703
IPC2.peptide.svr19 5.641
Protein with the highest isoelectric point:
>tr|A0A1L3KJ54|A0A1L3KJ54_9VIRU RNA-directed RNA polymerase OS=Hubei picorna-like virus 45 OX=1923126 PE=4 SV=1
MM1 pKa = 6.96 STNGKK6 pKa = 8.76 NFSVTRR12 pKa = 11.84 QPPMGQPLEE21 pKa = 4.28 RR22 pKa = 11.84 EE23 pKa = 4.58 AISEE27 pKa = 4.4 SVGTPTHH34 pKa = 6.05 VGISTLMQNWNLHH47 pKa = 4.58 GLKK50 pKa = 9.28 MEE52 pKa = 4.85 PFHH55 pKa = 6.88 DD56 pKa = 3.71 TVKK59 pKa = 10.66 RR60 pKa = 11.84 FVGQGRR66 pKa = 11.84 LPRR69 pKa = 11.84 CGNFSPKK76 pKa = 9.14 MMKK79 pKa = 8.39 ITNKK83 pKa = 10.13 KK84 pKa = 9.61 GEE86 pKa = 4.15 QVDD89 pKa = 5.32 IIDD92 pKa = 3.6 PWSYY96 pKa = 11.54 RR97 pKa = 11.84 DD98 pKa = 3.43 GKK100 pKa = 9.68 HH101 pKa = 4.98 QAEE104 pKa = 4.24 EE105 pKa = 4.02 MAIEE109 pKa = 4.42 TWALYY114 pKa = 7.52 DD115 pKa = 3.36 TRR117 pKa = 11.84 LPNRR121 pKa = 11.84 KK122 pKa = 8.07 FTWAQMEE129 pKa = 4.65 GARR132 pKa = 11.84 MACWFFLKK140 pKa = 10.51 DD141 pKa = 3.27 WIKK144 pKa = 8.56 YY145 pKa = 6.22 TKK147 pKa = 9.88 NASSKK152 pKa = 8.69 RR153 pKa = 11.84 QCIFGTCFMLLCAIEE168 pKa = 5.35 DD169 pKa = 3.83 EE170 pKa = 4.66 TTKK173 pKa = 10.86 KK174 pKa = 10.54 VDD176 pKa = 4.42 AICDD180 pKa = 3.98 KK181 pKa = 9.93 IHH183 pKa = 6.73 RR184 pKa = 11.84 RR185 pKa = 11.84 YY186 pKa = 9.86 GQAPPPSEE194 pKa = 5.02 KK195 pKa = 9.88 ILPAPTPFKK204 pKa = 10.67 LVSQLSVEE212 pKa = 4.18 ALSYY216 pKa = 11.13 ALEE219 pKa = 4.24 EE220 pKa = 4.32 VADD223 pKa = 3.77 IPMEE227 pKa = 3.89 RR228 pKa = 11.84 ARR230 pKa = 11.84 VQKK233 pKa = 11.01 ASVSYY238 pKa = 9.27 EE239 pKa = 4.06 KK240 pKa = 10.58 PLTAQMVTVSPPVFTSKK257 pKa = 10.62 DD258 pKa = 3.61 VPVSTGFSPMDD269 pKa = 3.08 IDD271 pKa = 4.23 AFDD274 pKa = 4.6 RR275 pKa = 11.84 EE276 pKa = 4.55 VAANLAEE283 pKa = 4.31 VSDD286 pKa = 3.91 LFKK289 pKa = 10.92 NLKK292 pKa = 8.19 EE293 pKa = 3.97 HH294 pKa = 6.95 EE295 pKa = 4.2 EE296 pKa = 4.27 MIGSGEE302 pKa = 4.15 VEE304 pKa = 4.19 EE305 pKa = 4.42 EE306 pKa = 3.9 EE307 pKa = 4.09 PMEE310 pKa = 4.1 VEE312 pKa = 4.11 EE313 pKa = 4.83 IKK315 pKa = 10.5 PIEE318 pKa = 4.02 MNPYY322 pKa = 7.89 QWEE325 pKa = 4.13 FSHH328 pKa = 6.16 YY329 pKa = 10.77 LKK331 pKa = 10.84 LKK333 pKa = 8.09 SQAVIEE339 pKa = 4.33 AQLLLQKK346 pKa = 10.3 VDD348 pKa = 4.33 PLNLTCKK355 pKa = 9.94 CWNCVEE361 pKa = 4.08 RR362 pKa = 11.84 FLRR365 pKa = 11.84 RR366 pKa = 11.84 NPYY369 pKa = 10.2 ALHH372 pKa = 5.73 NQINVCPDD380 pKa = 2.69 QCLYY384 pKa = 11.14 TNDD387 pKa = 4.11 FVDD390 pKa = 3.15 KK391 pKa = 10.34 TEE393 pKa = 4.07 RR394 pKa = 11.84 ARR396 pKa = 11.84 LAHH399 pKa = 7.39 RR400 pKa = 11.84 ARR402 pKa = 11.84 CLEE405 pKa = 3.92 VLTGRR410 pKa = 11.84 VSEE413 pKa = 4.31 YY414 pKa = 10.8 QMCSHH419 pKa = 6.75 EE420 pKa = 4.4 VVDD423 pKa = 3.89 WANTEE428 pKa = 3.95 SQEE431 pKa = 4.47 FFDD434 pKa = 5.82 EE435 pKa = 4.78 EE436 pKa = 4.82 YY437 pKa = 11.07 EE438 pKa = 5.38 DD439 pKa = 3.63 MAQIQGSEE447 pKa = 4.25 EE448 pKa = 4.37 CVSLDD453 pKa = 4.97 DD454 pKa = 5.62 LDD456 pKa = 6.17 LNTFMCEE463 pKa = 3.46 IEE465 pKa = 4.76 LDD467 pKa = 3.92 YY468 pKa = 11.45 FMEE471 pKa = 4.41 QAGAPDD477 pKa = 4.02 WRR479 pKa = 11.84 ILWVTDD485 pKa = 3.48 EE486 pKa = 4.6 EE487 pKa = 4.3 PWSIFEE493 pKa = 4.69 QEE495 pKa = 4.5 EE496 pKa = 4.07 LHH498 pKa = 6.68 QLYY501 pKa = 10.45 LQMLEE506 pKa = 4.74 DD507 pKa = 4.18 EE508 pKa = 4.73 SEE510 pKa = 4.35 EE511 pKa = 4.5 LPFAQMDD518 pKa = 3.7 EE519 pKa = 4.44 CLEE522 pKa = 4.05 SHH524 pKa = 6.61 EE525 pKa = 4.95 SVEE528 pKa = 4.2 KK529 pKa = 9.18 TQNLTFVDD537 pKa = 4.2 EE538 pKa = 4.78 RR539 pKa = 11.84 PVDD542 pKa = 3.35 RR543 pKa = 11.84 AGAYY547 pKa = 9.8 LGSSSRR553 pKa = 11.84 TYY555 pKa = 10.71 DD556 pKa = 2.93 INRR559 pKa = 11.84 SIAEE563 pKa = 4.33 KK564 pKa = 9.95 PWTLNATLDD573 pKa = 3.59 RR574 pKa = 11.84 EE575 pKa = 4.32 IPVAEE580 pKa = 4.74 FEE582 pKa = 4.58 WNTQGVFTNLVEE594 pKa = 4.98 LPFPKK599 pKa = 10.33 CYY601 pKa = 9.44 TDD603 pKa = 3.69 KK604 pKa = 10.63 SANMGRR610 pKa = 11.84 NIVKK614 pKa = 10.08 NFGFLRR620 pKa = 11.84 SDD622 pKa = 3.14 AYY624 pKa = 10.82 FRR626 pKa = 11.84 IQLNGNRR633 pKa = 11.84 FDD635 pKa = 4.34 QGRR638 pKa = 11.84 LVCWLRR644 pKa = 11.84 PLTWSVDD651 pKa = 3.54 KK652 pKa = 11.17 KK653 pKa = 10.79 RR654 pKa = 11.84 LSPSNFANLAHH665 pKa = 6.3 VFLDD669 pKa = 3.54 ASVSNSGVLTMPYY682 pKa = 8.84 THH684 pKa = 7.11 MLTHH688 pKa = 6.67 FCIKK692 pKa = 9.9 PKK694 pKa = 10.5 KK695 pKa = 10.57 LEE697 pKa = 4.58 DD698 pKa = 4.01 DD699 pKa = 4.43 SMSCLCTLVITVLNKK714 pKa = 10.2 LRR716 pKa = 11.84 VGEE719 pKa = 4.3 GAPPTLFGTVYY730 pKa = 10.94 AKK732 pKa = 10.75 LDD734 pKa = 3.79 NPVLHH739 pKa = 5.45 QVCYY743 pKa = 10.2 TSDD746 pKa = 3.02 TMSFDD751 pKa = 3.24 STTGYY756 pKa = 10.73 VDD758 pKa = 4.98 SLDD761 pKa = 4.05 NPNAPAIIQGEE772 pKa = 3.94 PGIWEE777 pKa = 3.91 KK778 pKa = 10.96 AAATGVGQALGNVLKK793 pKa = 11.18 LMTGGLATGVGNFLGGLIFDD813 pKa = 4.63 RR814 pKa = 11.84 PIDD817 pKa = 3.97 PRR819 pKa = 11.84 PVEE822 pKa = 3.91 PVLNRR827 pKa = 11.84 SVQPMCYY834 pKa = 9.87 AVGPDD839 pKa = 3.03 SSVRR843 pKa = 11.84 MGMTPISQRR852 pKa = 11.84 EE853 pKa = 3.95 SRR855 pKa = 11.84 PAMVASNFDD864 pKa = 3.63 DD865 pKa = 3.73 MNFDD869 pKa = 5.67 KK870 pKa = 10.77 ILQTYY875 pKa = 8.42 QLLYY879 pKa = 10.13 SDD881 pKa = 5.5 SISTSTSVKK890 pKa = 10.29 SRR892 pKa = 11.84 VARR895 pKa = 11.84 LPVCPTFIPSTDD907 pKa = 3.19 INNLSTTGVRR917 pKa = 11.84 YY918 pKa = 9.82 RR919 pKa = 11.84 PTALAYY925 pKa = 9.6 ISRR928 pKa = 11.84 AFAYY932 pKa = 10.71 YY933 pKa = 10.21 EE934 pKa = 4.14 GSLVFKK940 pKa = 9.95 FQFVTSQFHH949 pKa = 5.55 SMRR952 pKa = 11.84 IGIAFDD958 pKa = 3.92 PLDD961 pKa = 4.65 DD962 pKa = 3.88 FTEE965 pKa = 4.91 EE966 pKa = 3.55 ISYY969 pKa = 9.89 EE970 pKa = 4.08 QIFNMNMGLFDD981 pKa = 3.4 IQEE984 pKa = 3.93 QKK986 pKa = 10.7 EE987 pKa = 4.19 IEE989 pKa = 4.67 FVCPMTSTRR998 pKa = 11.84 SWLRR1002 pKa = 11.84 CDD1004 pKa = 4.42 RR1005 pKa = 11.84 FRR1007 pKa = 11.84 SDD1009 pKa = 4.27 ANFSGAGAEE1018 pKa = 4.09 EE1019 pKa = 4.72 LNRR1022 pKa = 11.84 EE1023 pKa = 4.05 PLNRR1027 pKa = 11.84 SSMGSLSMWIVNRR1040 pKa = 11.84 LVAPEE1045 pKa = 4.39 NVSQTIDD1052 pKa = 3.34 FNIFIKK1058 pKa = 10.51 AGKK1061 pKa = 9.48 DD1062 pKa = 3.12 FRR1064 pKa = 11.84 LAIPVPLHH1072 pKa = 6.0 PLRR1075 pKa = 11.84 LTPAVDD1081 pKa = 3.81 TFAQIPDD1088 pKa = 3.63 SQYY1091 pKa = 10.97 VFAPNCPPNLIGSPGMFEE1109 pKa = 3.46 NKK1111 pKa = 10.26 AYY1113 pKa = 9.72 IEE1115 pKa = 3.79 YY1116 pKa = 9.73 LYY1118 pKa = 10.8 RR1119 pKa = 11.84 VGRR1122 pKa = 11.84 QFYY1125 pKa = 11.18 LEE1127 pKa = 4.28 GKK1129 pKa = 8.41 LTIPTDD1135 pKa = 4.44 GYY1137 pKa = 9.83 WWQCVPNLQLGYY1149 pKa = 10.66 VDD1151 pKa = 6.3 DD1152 pKa = 4.11 VLAWRR1157 pKa = 11.84 DD1158 pKa = 3.57 KK1159 pKa = 11.35 ASLLSTYY1166 pKa = 10.84 TNDD1169 pKa = 3.52 TPQWQYY1175 pKa = 10.12 MASLLPYY1182 pKa = 8.12 VNKK1185 pKa = 9.59 WRR1187 pKa = 11.84 IPTDD1191 pKa = 3.02 DD1192 pKa = 3.11 WAKK1195 pKa = 10.75 PKK1197 pKa = 10.91 DD1198 pKa = 3.81 SDD1200 pKa = 3.85 SFKK1203 pKa = 10.83 YY1204 pKa = 10.77 LKK1206 pKa = 10.47 DD1207 pKa = 3.61 DD1208 pKa = 3.73 GAIVQGSVEE1217 pKa = 4.13 VATTSRR1223 pKa = 11.84 EE1224 pKa = 3.89 QGAEE1228 pKa = 4.08 PIVPTRR1234 pKa = 11.84 GMQTAEE1240 pKa = 4.17 AAPTTISEE1248 pKa = 4.23 NAQNLQTVMRR1258 pKa = 11.84 RR1259 pKa = 11.84 YY1260 pKa = 8.78 YY1261 pKa = 9.74 PLYY1264 pKa = 9.81 EE1265 pKa = 4.34 SEE1267 pKa = 4.99 PIYY1270 pKa = 11.09 NSLGYY1275 pKa = 8.4 TLITVPVTPTCLTAEE1290 pKa = 4.79 FKK1292 pKa = 10.31 PYY1294 pKa = 9.63 KK1295 pKa = 9.89 GKK1297 pKa = 11.17 VMFNRR1302 pKa = 11.84 ILHH1305 pKa = 6.39 PIAYY1309 pKa = 9.6 FSRR1312 pKa = 11.84 LFNYY1316 pKa = 8.05 WAGSLSYY1323 pKa = 10.49 RR1324 pKa = 11.84 IIVKK1328 pKa = 9.58 SRR1330 pKa = 11.84 KK1331 pKa = 7.18 TSRR1334 pKa = 11.84 KK1335 pKa = 8.91 VYY1337 pKa = 10.38 AIYY1340 pKa = 10.4 DD1341 pKa = 3.42 PRR1343 pKa = 11.84 TTVNFRR1349 pKa = 11.84 VLSGIMFDD1357 pKa = 3.81 RR1358 pKa = 11.84 LSHH1361 pKa = 6.22 RR1362 pKa = 11.84 MNLATVLSVSHH1373 pKa = 6.08 LQGSVDD1379 pKa = 3.68 VQVPWSSRR1387 pKa = 11.84 YY1388 pKa = 9.33 DD1389 pKa = 3.22 QGLIEE1394 pKa = 5.41 LDD1396 pKa = 3.92 EE1397 pKa = 4.96 DD1398 pKa = 3.99 LQDD1401 pKa = 4.69 LRR1403 pKa = 11.84 SQNGTLEE1410 pKa = 4.01 IYY1412 pKa = 10.29 IEE1414 pKa = 4.41 NDD1416 pKa = 2.64 TDD1418 pKa = 4.16 LEE1420 pKa = 4.39 PFGTDD1425 pKa = 2.93 PFTVSVFLSTGDD1437 pKa = 3.87 DD1438 pKa = 3.67 FVLNLYY1444 pKa = 10.18 RR1445 pKa = 11.84 GPTYY1449 pKa = 10.01 IYY1451 pKa = 9.21 EE1452 pKa = 4.53 CKK1454 pKa = 10.5 YY1455 pKa = 9.59 LTNSYY1460 pKa = 10.66 SGAKK1464 pKa = 9.27 SMCVKK1469 pKa = 10.62 YY1470 pKa = 10.78 PEE1472 pKa = 4.02 FQYY1475 pKa = 11.5 NNSIRR1480 pKa = 11.84 DD1481 pKa = 3.46 WGNYY1485 pKa = 7.02 PATNLGRR1492 pKa = 11.84 PQWPRR1497 pKa = 11.84 PGGVYY1502 pKa = 10.65 NFGTTEE1508 pKa = 3.99 VQSNCDD1514 pKa = 3.49 PLTPKK1519 pKa = 10.42 SFQEE1523 pKa = 3.71 IVKK1526 pKa = 10.14 RR1527 pKa = 11.84 KK1528 pKa = 9.61 AGAFGKK1534 pKa = 9.34 SVKK1537 pKa = 10.37 GPSALFCPPPTITEE1551 pKa = 4.14 GNEE1554 pKa = 3.59 IQHH1557 pKa = 6.3 FEE1559 pKa = 4.09 EE1560 pKa = 4.81 LLEE1563 pKa = 4.53 GTDD1566 pKa = 3.64 GAVIQGLFADD1576 pKa = 4.26 LRR1578 pKa = 11.84 KK1579 pKa = 9.51 MKK1581 pKa = 10.84 NNVVDD1586 pKa = 3.96 SSTALKK1592 pKa = 10.76 NILTRR1597 pKa = 11.84 VDD1599 pKa = 3.55 EE1600 pKa = 4.66 TNLSEE1605 pKa = 5.92 GIACLVQKK1613 pKa = 11.08 ANAFTNGISEE1623 pKa = 4.6 SVSTPAVAASVAKK1636 pKa = 10.58 YY1637 pKa = 10.16 SVLSAEE1643 pKa = 4.28 ILTVGAFIYY1652 pKa = 10.23 SLKK1655 pKa = 10.8 EE1656 pKa = 3.75 CFQNPNLKK1664 pKa = 10.16 NFIMLSITAAGCIGFAVSNALQSVITNVVNWALSCEE1700 pKa = 4.29 LPQTQALDD1708 pKa = 3.4 GATAQVIDD1716 pKa = 3.98 SHH1718 pKa = 8.33 SSTICTVVAVIATVFYY1734 pKa = 10.64 AYY1736 pKa = 9.68 IFDD1739 pKa = 4.34 VLPSMTTLKK1748 pKa = 10.8 EE1749 pKa = 4.0 GFRR1752 pKa = 11.84 KK1753 pKa = 10.26 LFGDD1757 pKa = 5.98 DD1758 pKa = 2.84 IDD1760 pKa = 4.95 LPKK1763 pKa = 10.42 KK1764 pKa = 10.26 PKK1766 pKa = 10.66 AKK1768 pKa = 9.75 IQAKK1772 pKa = 9.99 GFEE1775 pKa = 4.63 LKK1777 pKa = 10.21 NAHH1780 pKa = 6.55 FSLLGITALDD1790 pKa = 3.53 KK1791 pKa = 11.37 VYY1793 pKa = 10.34 TKK1795 pKa = 10.7 CLDD1798 pKa = 3.6 MVSSFLDD1805 pKa = 3.78 WILEE1809 pKa = 3.81 RR1810 pKa = 11.84 DD1811 pKa = 3.77 NPGVIAARR1819 pKa = 11.84 TTQEE1823 pKa = 3.43 YY1824 pKa = 9.92 RR1825 pKa = 11.84 DD1826 pKa = 4.06 RR1827 pKa = 11.84 IMHH1830 pKa = 6.27 CVNEE1834 pKa = 4.7 LDD1836 pKa = 4.68 LLDD1839 pKa = 3.96 NEE1841 pKa = 5.26 EE1842 pKa = 4.43 YY1843 pKa = 9.03 FTNAMHH1849 pKa = 7.83 DD1850 pKa = 3.8 PFIHH1854 pKa = 5.5 NRR1856 pKa = 11.84 FYY1858 pKa = 11.58 KK1859 pKa = 10.64 LQGEE1863 pKa = 4.48 LNDD1866 pKa = 3.98 LTSLSLRR1873 pKa = 11.84 EE1874 pKa = 4.24 KK1875 pKa = 10.72 KK1876 pKa = 10.25 EE1877 pKa = 3.93 VMDD1880 pKa = 3.73 SQVRR1884 pKa = 11.84 NLISEE1889 pKa = 4.2 CRR1891 pKa = 11.84 KK1892 pKa = 9.89 RR1893 pKa = 11.84 CQKK1896 pKa = 10.41 LIKK1899 pKa = 9.82 EE1900 pKa = 4.69 LEE1902 pKa = 4.16 RR1903 pKa = 11.84 DD1904 pKa = 3.49 SPKK1907 pKa = 10.83 PMLRR1911 pKa = 11.84 YY1912 pKa = 10.08 DD1913 pKa = 4.77 PICICLCGEE1922 pKa = 4.19 SGTGKK1927 pKa = 8.49 TKK1929 pKa = 10.55 LMHH1932 pKa = 7.01 KK1933 pKa = 9.68 IADD1936 pKa = 4.04 VIKK1939 pKa = 10.68 EE1940 pKa = 4.03 EE1941 pKa = 4.13 MDD1943 pKa = 3.43 LPRR1946 pKa = 11.84 YY1947 pKa = 9.27 NLIYY1951 pKa = 10.19 PKK1953 pKa = 10.42 GIKK1956 pKa = 10.14 DD1957 pKa = 4.05 EE1958 pKa = 4.4 FWSGYY1963 pKa = 9.2 KK1964 pKa = 9.65 NQPIVFWDD1972 pKa = 3.79 EE1973 pKa = 3.85 FAQSRR1978 pKa = 11.84 KK1979 pKa = 7.3 MDD1981 pKa = 3.59 EE1982 pKa = 4.43 VIPEE1986 pKa = 4.21 FMTLRR1991 pKa = 11.84 GSTPVMLNMAALNDD2005 pKa = 3.42 KK2006 pKa = 10.68 GKK2008 pKa = 10.51 YY2009 pKa = 6.7 FTSQAMVLTTNVPFEE2024 pKa = 4.72 DD2025 pKa = 4.62 FNAVRR2030 pKa = 11.84 DD2031 pKa = 3.85 NNAFKK2036 pKa = 10.68 RR2037 pKa = 11.84 RR2038 pKa = 11.84 RR2039 pKa = 11.84 HH2040 pKa = 5.42 LLIKK2044 pKa = 9.41 LTHH2047 pKa = 6.31 RR2048 pKa = 11.84 PGFNAMNMQNARR2060 pKa = 11.84 HH2061 pKa = 5.9 DD2062 pKa = 3.59 QFPNWEE2068 pKa = 4.18 HH2069 pKa = 7.33 CFFTLMNPMQDD2080 pKa = 2.99 TAIADD2085 pKa = 4.05 GLDD2088 pKa = 3.17 LTTILEE2094 pKa = 4.35 MVRR2097 pKa = 11.84 LRR2099 pKa = 11.84 VRR2101 pKa = 11.84 RR2102 pKa = 11.84 WHH2104 pKa = 5.39 QNQMAILGAEE2114 pKa = 4.63 DD2115 pKa = 4.93 LPQEE2119 pKa = 4.31 MPRR2122 pKa = 11.84 GIVPIDD2128 pKa = 3.34 NNDD2131 pKa = 3.36 NLNYY2135 pKa = 10.72 DD2136 pKa = 3.79 EE2137 pKa = 5.49 ALEE2140 pKa = 4.08 TLALAEE2146 pKa = 3.99 QAAFEE2151 pKa = 4.78 AIEE2154 pKa = 4.2 EE2155 pKa = 4.17 EE2156 pKa = 4.23 HH2157 pKa = 7.54 LEE2159 pKa = 4.69 AEE2161 pKa = 4.5 NEE2163 pKa = 3.86 FHH2165 pKa = 7.08 NPVNIQQDD2173 pKa = 2.91 IAMNLDD2179 pKa = 3.46 GVPRR2183 pKa = 11.84 EE2184 pKa = 4.15 AFEE2187 pKa = 4.95 ALPEE2191 pKa = 4.22 YY2192 pKa = 10.15 YY2193 pKa = 9.93 RR2194 pKa = 11.84 PPPEE2198 pKa = 3.87 VGPIVDD2204 pKa = 3.8 VEE2206 pKa = 4.38 GAGARR2211 pKa = 11.84 IQMMVEE2217 pKa = 4.06 DD2218 pKa = 4.37 EE2219 pKa = 5.14 DD2220 pKa = 5.22 EE2221 pKa = 4.49 IFVDD2225 pKa = 4.41 CQEE2228 pKa = 4.36 SPFGFVDD2235 pKa = 3.56 YY2236 pKa = 10.99 VRR2238 pKa = 11.84 EE2239 pKa = 3.8 EE2240 pKa = 4.3 RR2241 pKa = 11.84 EE2242 pKa = 3.95 FVTEE2246 pKa = 3.95 CVYY2249 pKa = 11.2 AKK2251 pKa = 10.17 QPVMSVYY2258 pKa = 9.76 PWTAEE2263 pKa = 4.08 EE2264 pKa = 4.07 IKK2266 pKa = 10.74 KK2267 pKa = 10.39 VATKK2271 pKa = 8.34 TKK2273 pKa = 10.28 CRR2275 pKa = 11.84 LFRR2278 pKa = 11.84 LAEE2281 pKa = 4.36 DD2282 pKa = 3.85 CSEE2285 pKa = 4.29 QIALAARR2292 pKa = 11.84 SFLRR2296 pKa = 11.84 SQYY2299 pKa = 8.41 TQSLINKK2306 pKa = 7.76 VRR2308 pKa = 11.84 TNNLWIKK2315 pKa = 9.75 AQNFCSEE2322 pKa = 4.72 LKK2324 pKa = 10.02 QDD2326 pKa = 6.13 LIMCFDD2332 pKa = 4.88 KK2333 pKa = 10.72 IKK2335 pKa = 9.88 KK2336 pKa = 8.14 TIYY2339 pKa = 11.06 DD2340 pKa = 3.78 MIEE2343 pKa = 3.59 NHH2345 pKa = 5.98 PRR2347 pKa = 11.84 IAKK2350 pKa = 9.65 VVGAMTLFAGVGGVLYY2366 pKa = 10.83 AFGNTQSVPIQEE2378 pKa = 4.0 EE2379 pKa = 4.58 GFYY2382 pKa = 10.31 EE2383 pKa = 4.04 SHH2385 pKa = 6.89 IPRR2388 pKa = 11.84 MCRR2391 pKa = 11.84 PRR2393 pKa = 11.84 IIPEE2397 pKa = 4.06 SYY2399 pKa = 9.89 EE2400 pKa = 4.1 AGPDD2404 pKa = 2.82 RR2405 pKa = 11.84 AARR2408 pKa = 11.84 PRR2410 pKa = 11.84 IIPEE2414 pKa = 3.85 SCVDD2418 pKa = 3.66 CEE2420 pKa = 4.18 GAYY2423 pKa = 10.14 EE2424 pKa = 4.38 GGPARR2429 pKa = 11.84 CARR2432 pKa = 11.84 WRR2434 pKa = 11.84 VVPEE2438 pKa = 4.04 GAACQGCEE2446 pKa = 4.88 DD2447 pKa = 4.61 KK2448 pKa = 11.02 PAMDD2452 pKa = 3.77 IRR2454 pKa = 11.84 AKK2456 pKa = 10.12 VHH2458 pKa = 5.94 PAVCRR2463 pKa = 11.84 IRR2465 pKa = 11.84 WDD2467 pKa = 3.47 TTADD2471 pKa = 3.43 GGVGQLNCTRR2481 pKa = 11.84 IGGSLILLPYY2491 pKa = 10.35 HH2492 pKa = 6.2 FFRR2495 pKa = 11.84 YY2496 pKa = 9.65 RR2497 pKa = 11.84 KK2498 pKa = 8.08 TGDD2501 pKa = 3.1 KK2502 pKa = 10.59 FSILHH2507 pKa = 6.54 RR2508 pKa = 11.84 MTTLIYY2514 pKa = 10.14 EE2515 pKa = 4.22 YY2516 pKa = 10.44 DD2517 pKa = 3.77 EE2518 pKa = 4.22 KK2519 pKa = 11.58 RR2520 pKa = 11.84 MFRR2523 pKa = 11.84 EE2524 pKa = 4.49 GAKK2527 pKa = 10.46 DD2528 pKa = 3.04 WVLYY2532 pKa = 10.72 DD2533 pKa = 3.42 LGFRR2537 pKa = 11.84 IEE2539 pKa = 4.07 PAKK2542 pKa = 10.77 HH2543 pKa = 4.85 LFKK2546 pKa = 11.3 YY2547 pKa = 9.82 FVSEE2551 pKa = 3.97 KK2552 pKa = 10.9 NLVRR2556 pKa = 11.84 KK2557 pKa = 10.11 CNAILLAADD2566 pKa = 3.32 VDD2568 pKa = 4.41 GTLKK2572 pKa = 8.39 MTSGKK2577 pKa = 8.95 ATGDD2581 pKa = 3.17 AFFQYY2586 pKa = 10.67 TDD2588 pKa = 4.17 LKK2590 pKa = 10.88 GDD2592 pKa = 3.67 TYY2594 pKa = 10.93 KK2595 pKa = 10.73 QRR2597 pKa = 11.84 GWRR2600 pKa = 11.84 IEE2602 pKa = 3.92 MTTVQGDD2609 pKa = 3.75 CGGLLMGLGAHH2620 pKa = 7.08 LPPPGKK2626 pKa = 9.88 ILGIHH2631 pKa = 5.25 VAGYY2635 pKa = 8.67 HH2636 pKa = 5.58 NKK2638 pKa = 10.48 AIGYY2642 pKa = 8.28 DD2643 pKa = 3.53 VLITRR2648 pKa = 11.84 EE2649 pKa = 4.02 QLEE2652 pKa = 4.38 SLASKK2657 pKa = 10.79 AGILFNEE2664 pKa = 4.34 SPIPKK2669 pKa = 8.5 STDD2672 pKa = 2.53 VTAPLNTFRR2681 pKa = 11.84 LVPHH2685 pKa = 7.05 GDD2687 pKa = 3.39 FTIVGTMDD2695 pKa = 2.62 KK2696 pKa = 9.68 TKK2698 pKa = 10.72 RR2699 pKa = 11.84 VFQPMSSDD2707 pKa = 3.95 LKK2709 pKa = 8.16 PTPWANEE2716 pKa = 3.51 ITDD2719 pKa = 3.92 FPNPKK2724 pKa = 9.75 KK2725 pKa = 9.62 PAHH2728 pKa = 6.12 LMPFKK2733 pKa = 10.79 NADD2736 pKa = 3.47 GNRR2739 pKa = 11.84 ISPLALALPKK2749 pKa = 10.09 YY2750 pKa = 10.32 GKK2752 pKa = 10.35 VSLPLPVRR2760 pKa = 11.84 SIDD2763 pKa = 3.78 KK2764 pKa = 10.34 IVSFLSDD2771 pKa = 3.54 YY2772 pKa = 11.24 LEE2774 pKa = 4.16 SHH2776 pKa = 5.94 LTEE2779 pKa = 4.13 HH2780 pKa = 5.66 TGKK2783 pKa = 10.78 RR2784 pKa = 11.84 IFSDD2788 pKa = 4.04 LEE2790 pKa = 3.95 AVNGIVGVEE2799 pKa = 3.8 YY2800 pKa = 11.01 AEE2802 pKa = 4.11 RR2803 pKa = 11.84 LNMKK2807 pKa = 10.0 SSPGWPYY2814 pKa = 10.2 QIEE2817 pKa = 4.3 NRR2819 pKa = 11.84 GEE2821 pKa = 3.62 PGKK2824 pKa = 10.57 FHH2826 pKa = 7.32 FFDD2829 pKa = 4.18 EE2830 pKa = 5.15 DD2831 pKa = 3.48 GHH2833 pKa = 8.64 IIDD2836 pKa = 4.88 EE2837 pKa = 4.26 KK2838 pKa = 9.97 LQRR2841 pKa = 11.84 RR2842 pKa = 11.84 LDD2844 pKa = 3.67 YY2845 pKa = 10.92 RR2846 pKa = 11.84 IDD2848 pKa = 3.36 EE2849 pKa = 4.33 ARR2851 pKa = 11.84 EE2852 pKa = 3.88 GRR2854 pKa = 11.84 RR2855 pKa = 11.84 VASLWRR2861 pKa = 11.84 DD2862 pKa = 3.49 CLKK2865 pKa = 11.18 DD2866 pKa = 3.38 EE2867 pKa = 4.88 LRR2869 pKa = 11.84 PIEE2872 pKa = 5.27 KK2873 pKa = 9.8 VDD2875 pKa = 3.34 QGKK2878 pKa = 7.76 TRR2880 pKa = 11.84 LFTIAPLDD2888 pKa = 3.4 FTIAVRR2894 pKa = 11.84 KK2895 pKa = 9.7 YY2896 pKa = 10.2 FFDD2899 pKa = 4.11 FVIAFYY2905 pKa = 10.8 SAARR2909 pKa = 11.84 SDD2911 pKa = 3.68 FFSAVGIDD2919 pKa = 4.02 PEE2921 pKa = 4.34 SLDD2924 pKa = 3.1 WTFLYY2929 pKa = 10.77 NRR2931 pKa = 11.84 LRR2933 pKa = 11.84 EE2934 pKa = 4.04 ISDD2937 pKa = 3.34 NAVAGDD2943 pKa = 3.62 YY2944 pKa = 11.15 SGFDD2948 pKa = 3.19 GGLKK2952 pKa = 10.3 PEE2954 pKa = 5.0 AIEE2957 pKa = 5.4 AICKK2961 pKa = 10.1 LINLWYY2967 pKa = 10.21 NDD2969 pKa = 3.4 SPEE2972 pKa = 4.15 NQNVRR2977 pKa = 11.84 RR2978 pKa = 11.84 VLFLEE2983 pKa = 4.54 MCHH2986 pKa = 5.85 TLHH2989 pKa = 7.03 LVNDD2993 pKa = 4.64 CVYY2996 pKa = 10.32 MSHH2999 pKa = 6.51 QGNKK3003 pKa = 9.65 SGNPLTVIINTLANLIYY3020 pKa = 10.31 LLCAWIDD3027 pKa = 3.47 IYY3029 pKa = 10.54 PDD3031 pKa = 3.28 RR3032 pKa = 11.84 PIEE3035 pKa = 5.25 EE3036 pKa = 3.97 FFKK3039 pKa = 9.37 WCRR3042 pKa = 11.84 AIIYY3046 pKa = 10.53 GDD3048 pKa = 3.92 DD3049 pKa = 3.72 LLITVSDD3056 pKa = 3.79 KK3057 pKa = 9.82 VTKK3060 pKa = 10.53 FNQKK3064 pKa = 7.77 TLTASLAKK3072 pKa = 10.32 FGIVFTNEE3080 pKa = 3.73 MKK3082 pKa = 10.68 DD3083 pKa = 3.56 DD3084 pKa = 3.99 SDD3086 pKa = 3.76 VGEE3089 pKa = 4.32 FRR3091 pKa = 11.84 SLDD3094 pKa = 3.18 EE3095 pKa = 3.89 VTFLKK3100 pKa = 10.56 RR3101 pKa = 11.84 GFRR3104 pKa = 11.84 KK3105 pKa = 10.41 DD3106 pKa = 3.42 PEE3108 pKa = 4.27 VGHH3111 pKa = 7.12 LFTLPVMSEE3120 pKa = 4.18 EE3121 pKa = 4.28 TLHH3124 pKa = 7.31 SYY3126 pKa = 9.68 LFWYY3130 pKa = 9.97 RR3131 pKa = 11.84 ATEE3134 pKa = 4.1 EE3135 pKa = 4.04 EE3136 pKa = 4.94 DD3137 pKa = 3.91 EE3138 pKa = 4.3 EE3139 pKa = 4.37 QLRR3142 pKa = 11.84 QNMRR3146 pKa = 11.84 AALNFAFFRR3155 pKa = 11.84 GRR3157 pKa = 11.84 TFYY3160 pKa = 10.75 EE3161 pKa = 4.33 WYY3163 pKa = 9.46 NKK3165 pKa = 8.68 LWKK3168 pKa = 10.29 EE3169 pKa = 4.22 CMRR3172 pKa = 11.84 KK3173 pKa = 9.67 HH3174 pKa = 5.8 GFNPLSISYY3183 pKa = 10.23 DD3184 pKa = 3.49 EE3185 pKa = 4.38 QLDD3188 pKa = 3.51 IFLNKK3193 pKa = 10.08 AGALGEE3199 pKa = 4.01 IAPAQVQGLDD3209 pKa = 3.35 AFMKK3213 pKa = 10.58 ASNNKK3218 pKa = 7.34 WSRR3221 pKa = 11.84 RR3222 pKa = 11.84 FCGVTEE3228 pKa = 4.48 SIFYY3232 pKa = 8.11 YY3233 pKa = 10.61 LCAGLNVFKK3242 pKa = 10.67 CKK3244 pKa = 9.59 NLKK3247 pKa = 9.87 PPSDD3251 pKa = 4.17 DD3252 pKa = 2.83 RR3253 pKa = 11.84 WAVSIPSGEE3262 pKa = 4.4 GKK3264 pKa = 8.38 STLCKK3269 pKa = 9.18 MYY3271 pKa = 9.16 PHH3273 pKa = 7.16 IFVDD3277 pKa = 3.73 HH3278 pKa = 7.75 DD3279 pKa = 3.86 EE3280 pKa = 4.32 LLLPKK3285 pKa = 10.03 FQEE3288 pKa = 3.53 ISKK3291 pKa = 10.49 FNLSKK3296 pKa = 10.99 LPWRR3300 pKa = 11.84 AKK3302 pKa = 8.88 IARR3305 pKa = 11.84 EE3306 pKa = 3.48 IDD3308 pKa = 3.7 FPPEE3312 pKa = 3.49 DD3313 pKa = 3.58 RR3314 pKa = 11.84 RR3315 pKa = 11.84 ILLVHH3320 pKa = 6.49 SPANTKK3326 pKa = 10.5 RR3327 pKa = 11.84 NLIGCFVTPSPTYY3340 pKa = 8.43 IRR3342 pKa = 11.84 VNIFHH3347 pKa = 7.69 RR3348 pKa = 11.84 LLQNEE3353 pKa = 4.78 PYY3355 pKa = 11.34 VMDD3358 pKa = 4.33 FSEE3361 pKa = 5.89 RR3362 pKa = 11.84 NDD3364 pKa = 3.48 TLLRR3368 pKa = 11.84 LARR3371 pKa = 11.84 KK3372 pKa = 9.5 VEE3374 pKa = 4.29 PGLFEE3379 pKa = 6.26 ADD3381 pKa = 3.14
Molecular weight: 384.67 kDa
Isoelectric point according different methods:
IPC2.protein.svr19 5.307
IPC2_protein 5.359
IPC_protein 5.372
Toseland 5.461
ProMoST 5.563
Dawson 5.448
Bjellqvist 5.537
Wikipedia 5.359
Rodwell 5.385
Grimsley 5.448
Solomon 5.448
Lehninger 5.423
Nozaki 5.614
DTASelect 5.779
Thurlkill 5.55
EMBOSS 5.512
Sillero 5.703
Patrickios 4.024
IPC_peptide 5.461
IPC2_peptide 5.703
IPC2.peptide.svr19 5.641
Peptides (in silico digests for buttom-up proteomics)
Below you can find
in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.
Try ESI
ChTry ESI
ArgC ESI
LysN ESI
TryLysC ESI
Try MALDI
ChTry MALDI
ArgC MALDI
LysN MALDI
TryLysC MALDI
Try LTQ
ChTry LTQ
ArgC LTQ
LysN LTQ
TryLysC LTQ
Try MSlow
ChTry MSlow
ArgC MSlow
LysN MSlow
TryLysC MSlow
Try MShigh
ChTry MShigh
ArgC MShigh
LysN MShigh
TryLysC MShigh
General Statistics
Number of major isoforms
Number of additional isoforms
Number of all proteins
Number of amino acids
Min. Seq. Length
Max. Seq. Length
Avg. Seq. Length
Avg. Mol. Weight
1
0
1
3381
3381
3381
3381.0
384.67
Amino acid frequency
Ala
Cys
Asp
Glu
Phe
Gly
His
Ile
Lys
Leu
6.655 ± 0.0
2.189 ± 0.0
6.063 ± 0.0
6.951 ± 0.0
5.265 ± 0.0
5.442 ± 0.0
1.775 ± 0.0
5.679 ± 0.0
5.383 ± 0.0
8.903 ± 0.0
Met
Asn
Gln
Pro
Arg
Ser
Thr
Val
Trp
Tyr
2.839 ± 0.0
4.851 ± 0.0
5.738 ± 0.0
3.549 ± 0.0
5.62 ± 0.0
6.034 ± 0.0
5.649 ± 0.0
6.211 ± 0.0
1.597 ± 0.0
3.608 ± 0.0
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level
Most of the basic statistics you can see at this page can be downloaded from this CSV file
For dipeptide frequency statistics click here