Amino acid dipepetide frequency for Hubei tombus-like virus 32

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.843AlaAla: 1.843 ± 1.388
3.687AlaCys: 3.687 ± 1.452
0.922AlaAsp: 0.922 ± 0.694
3.687AlaGlu: 3.687 ± 1.452
4.608AlaPhe: 4.608 ± 1.829
5.53AlaGly: 5.53 ± 0.19
1.843AlaHis: 1.843 ± 0.063
1.843AlaIle: 1.843 ± 0.063
1.843AlaLys: 1.843 ± 0.063
5.53AlaLeu: 5.53 ± 1.515
1.843AlaMet: 1.843 ± 0.517
3.687AlaAsn: 3.687 ± 1.452
2.765AlaPro: 2.765 ± 2.083
2.765AlaGln: 2.765 ± 0.758
9.217AlaArg: 9.217 ± 1.642
4.608AlaSer: 4.608 ± 0.821
1.843AlaThr: 1.843 ± 1.261
3.687AlaVal: 3.687 ± 0.127
0.922AlaTrp: 0.922 ± 0.631
0.922AlaTyr: 0.922 ± 0.631
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.922CysCys: 0.922 ± 0.631
2.765CysAsp: 2.765 ± 0.758
0.0CysGlu: 0.0 ± 0.0
0.922CysPhe: 0.922 ± 0.694
2.765CysGly: 2.765 ± 0.758
2.765CysHis: 2.765 ± 0.758
0.0CysIle: 0.0 ± 0.0
0.922CysLys: 0.922 ± 0.694
4.608CysLeu: 4.608 ± 0.504
0.0CysMet: 0.0 ± 0.0
2.765CysAsn: 2.765 ± 0.567
1.843CysPro: 1.843 ± 0.063
0.922CysGln: 0.922 ± 0.631
1.843CysArg: 1.843 ± 0.063
1.843CysSer: 1.843 ± 1.261
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
1.843CysTyr: 1.843 ± 0.063
0.0CysXaa: 0.0 ± 0.0
Asp
6.452AspAla: 6.452 ± 0.44
1.843AspCys: 1.843 ± 1.261
6.452AspAsp: 6.452 ± 2.21
5.53AspGlu: 5.53 ± 1.515
1.843AspPhe: 1.843 ± 1.261
0.922AspGly: 0.922 ± 0.631
1.843AspHis: 1.843 ± 1.388
4.608AspIle: 4.608 ± 0.504
0.0AspLys: 0.0 ± 0.0
1.843AspLeu: 1.843 ± 1.261
3.687AspMet: 3.687 ± 1.198
3.687AspAsn: 3.687 ± 2.777
2.765AspPro: 2.765 ± 0.758
2.765AspGln: 2.765 ± 0.567
4.608AspArg: 4.608 ± 3.471
3.687AspSer: 3.687 ± 0.127
5.53AspThr: 5.53 ± 2.84
6.452AspVal: 6.452 ± 2.21
0.0AspTrp: 0.0 ± 0.0
0.922AspTyr: 0.922 ± 0.631
0.0AspXaa: 0.0 ± 0.0
Glu
3.687GluAla: 3.687 ± 0.127
1.843GluCys: 1.843 ± 1.388
5.53GluAsp: 5.53 ± 0.19
0.922GluGlu: 0.922 ± 0.694
5.53GluPhe: 5.53 ± 1.134
2.765GluGly: 2.765 ± 1.892
0.0GluHis: 0.0 ± 0.0
1.843GluIle: 1.843 ± 0.063
0.922GluLys: 0.922 ± 0.694
5.53GluLeu: 5.53 ± 1.515
1.843GluMet: 1.843 ± 0.063
1.843GluAsn: 1.843 ± 0.063
0.922GluPro: 0.922 ± 0.631
1.843GluGln: 1.843 ± 0.063
0.922GluArg: 0.922 ± 0.631
5.53GluSer: 5.53 ± 2.459
5.53GluThr: 5.53 ± 2.459
1.843GluVal: 1.843 ± 1.388
0.922GluTrp: 0.922 ± 0.631
0.922GluTyr: 0.922 ± 0.694
0.0GluXaa: 0.0 ± 0.0
Phe
1.843PheAla: 1.843 ± 1.261
1.843PheCys: 1.843 ± 1.261
4.608PheAsp: 4.608 ± 0.504
1.843PheGlu: 1.843 ± 1.261
0.922PhePhe: 0.922 ± 0.631
2.765PheGly: 2.765 ± 0.758
1.843PheHis: 1.843 ± 1.261
4.608PheIle: 4.608 ± 0.821
2.765PheLys: 2.765 ± 0.567
6.452PheLeu: 6.452 ± 1.765
0.0PheMet: 0.0 ± 0.0
5.53PheAsn: 5.53 ± 1.134
0.922PhePro: 0.922 ± 0.631
0.922PheGln: 0.922 ± 0.631
2.765PheArg: 2.765 ± 0.758
2.765PheSer: 2.765 ± 0.567
5.53PheThr: 5.53 ± 1.515
3.687PheVal: 3.687 ± 0.127
0.0PheTrp: 0.0 ± 0.0
2.765PheTyr: 2.765 ± 1.892
0.0PheXaa: 0.0 ± 0.0
Gly
0.922GlyAla: 0.922 ± 0.694
0.0GlyCys: 0.0 ± 0.0
3.687GlyAsp: 3.687 ± 2.523
3.687GlyGlu: 3.687 ± 0.127
4.608GlyPhe: 4.608 ± 0.504
1.843GlyGly: 1.843 ± 1.261
2.765GlyHis: 2.765 ± 0.567
0.922GlyIle: 0.922 ± 0.694
3.687GlyLys: 3.687 ± 1.452
8.295GlyLeu: 8.295 ± 0.377
0.0GlyMet: 0.0 ± 0.0
1.843GlyAsn: 1.843 ± 1.261
1.843GlyPro: 1.843 ± 1.388
1.843GlyGln: 1.843 ± 1.261
5.53GlyArg: 5.53 ± 0.19
2.765GlySer: 2.765 ± 1.892
2.765GlyThr: 2.765 ± 1.892
4.608GlyVal: 4.608 ± 0.821
0.922GlyTrp: 0.922 ± 0.631
0.922GlyTyr: 0.922 ± 0.694
0.0GlyXaa: 0.0 ± 0.0
His
2.765HisAla: 2.765 ± 0.758
1.843HisCys: 1.843 ± 0.063
0.922HisAsp: 0.922 ± 0.694
0.0HisGlu: 0.0 ± 0.0
1.843HisPhe: 1.843 ± 0.063
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
1.843HisIle: 1.843 ± 1.388
1.843HisLys: 1.843 ± 0.063
2.765HisLeu: 2.765 ± 0.567
0.922HisMet: 0.922 ± 0.631
1.843HisAsn: 1.843 ± 0.063
0.0HisPro: 0.0 ± 0.0
0.0HisGln: 0.0 ± 0.0
2.765HisArg: 2.765 ± 0.758
0.922HisSer: 0.922 ± 0.631
1.843HisThr: 1.843 ± 0.063
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
0.922HisTyr: 0.922 ± 0.631
0.0HisXaa: 0.0 ± 0.0
Ile
6.452IleAla: 6.452 ± 2.21
1.843IleCys: 1.843 ± 0.063
4.608IleAsp: 4.608 ± 0.821
2.765IleGlu: 2.765 ± 0.567
0.0IlePhe: 0.0 ± 0.0
1.843IleGly: 1.843 ± 0.063
0.922IleHis: 0.922 ± 0.631
4.608IleIle: 4.608 ± 2.146
0.0IleLys: 0.0 ± 0.0
3.687IleLeu: 3.687 ± 2.523
1.843IleMet: 1.843 ± 0.063
2.765IleAsn: 2.765 ± 1.892
3.687IlePro: 3.687 ± 0.127
0.0IleGln: 0.0 ± 0.0
3.687IleArg: 3.687 ± 1.198
3.687IleSer: 3.687 ± 0.127
3.687IleThr: 3.687 ± 1.198
2.765IleVal: 2.765 ± 0.567
0.0IleTrp: 0.0 ± 0.0
2.765IleTyr: 2.765 ± 2.083
0.0IleXaa: 0.0 ± 0.0
Lys
0.0LysAla: 0.0 ± 0.0
2.765LysCys: 2.765 ± 1.892
1.843LysAsp: 1.843 ± 1.388
0.922LysGlu: 0.922 ± 0.631
3.687LysPhe: 3.687 ± 0.127
2.765LysGly: 2.765 ± 1.892
1.843LysHis: 1.843 ± 0.063
5.53LysIle: 5.53 ± 1.134
0.922LysLys: 0.922 ± 0.631
3.687LysLeu: 3.687 ± 1.198
0.922LysMet: 0.922 ± 0.631
5.53LysAsn: 5.53 ± 1.134
2.765LysPro: 2.765 ± 0.567
0.922LysGln: 0.922 ± 0.631
1.843LysArg: 1.843 ± 0.063
5.53LysSer: 5.53 ± 2.459
2.765LysThr: 2.765 ± 0.567
0.922LysVal: 0.922 ± 0.694
0.922LysTrp: 0.922 ± 0.694
1.843LysTyr: 1.843 ± 1.261
0.0LysXaa: 0.0 ± 0.0
Leu
11.06LeuAla: 11.06 ± 4.356
1.843LeuCys: 1.843 ± 1.388
3.687LeuAsp: 3.687 ± 2.523
3.687LeuGlu: 3.687 ± 1.198
2.765LeuPhe: 2.765 ± 0.758
5.53LeuGly: 5.53 ± 0.19
0.922LeuHis: 0.922 ± 0.631
4.608LeuIle: 4.608 ± 0.504
3.687LeuLys: 3.687 ± 2.523
14.747LeuLeu: 14.747 ± 5.807
0.922LeuMet: 0.922 ± 0.694
3.687LeuAsn: 3.687 ± 2.523
4.608LeuPro: 4.608 ± 0.504
2.765LeuGln: 2.765 ± 0.758
11.982LeuArg: 11.982 ± 0.25
2.765LeuSer: 2.765 ± 2.083
8.295LeuThr: 8.295 ± 1.702
9.217LeuVal: 9.217 ± 0.317
0.922LeuTrp: 0.922 ± 0.694
2.765LeuTyr: 2.765 ± 0.567
0.0LeuXaa: 0.0 ± 0.0
Met
0.922MetAla: 0.922 ± 0.631
0.922MetCys: 0.922 ± 0.694
3.687MetAsp: 3.687 ± 0.127
2.765MetGlu: 2.765 ± 2.083
1.843MetPhe: 1.843 ± 0.063
0.922MetGly: 0.922 ± 0.631
0.0MetHis: 0.0 ± 0.0
0.922MetIle: 0.922 ± 0.631
0.922MetLys: 0.922 ± 0.631
1.843MetLeu: 1.843 ± 1.388
0.922MetMet: 0.922 ± 0.694
0.0MetAsn: 0.0 ± 0.0
0.0MetPro: 0.0 ± 0.0
1.843MetGln: 1.843 ± 0.063
0.0MetArg: 0.0 ± 0.0
3.687MetSer: 3.687 ± 0.127
0.0MetThr: 0.0 ± 0.0
1.843MetVal: 1.843 ± 1.261
0.0MetTrp: 0.0 ± 0.0
1.843MetTyr: 1.843 ± 1.261
0.0MetXaa: 0.0 ± 0.0
Asn
1.843AsnAla: 1.843 ± 0.063
0.922AsnCys: 0.922 ± 0.631
0.922AsnAsp: 0.922 ± 0.631
1.843AsnGlu: 1.843 ± 1.261
4.608AsnPhe: 4.608 ± 0.821
3.687AsnGly: 3.687 ± 1.452
0.0AsnHis: 0.0 ± 0.0
5.53AsnIle: 5.53 ± 2.459
2.765AsnLys: 2.765 ± 0.567
3.687AsnLeu: 3.687 ± 2.523
2.765AsnMet: 2.765 ± 0.758
1.843AsnAsn: 1.843 ± 1.388
2.765AsnPro: 2.765 ± 0.758
3.687AsnGln: 3.687 ± 1.452
4.608AsnArg: 4.608 ± 0.504
2.765AsnSer: 2.765 ± 0.758
1.843AsnThr: 1.843 ± 1.261
1.843AsnVal: 1.843 ± 1.261
0.922AsnTrp: 0.922 ± 0.694
2.765AsnTyr: 2.765 ± 0.567
0.0AsnXaa: 0.0 ± 0.0
Pro
1.843ProAla: 1.843 ± 1.388
0.0ProCys: 0.0 ± 0.0
4.608ProAsp: 4.608 ± 0.504
3.687ProGlu: 3.687 ± 1.198
0.922ProPhe: 0.922 ± 0.631
2.765ProGly: 2.765 ± 0.758
0.0ProHis: 0.0 ± 0.0
1.843ProIle: 1.843 ± 0.063
2.765ProLys: 2.765 ± 0.758
4.608ProLeu: 4.608 ± 0.504
0.922ProMet: 0.922 ± 0.694
0.0ProAsn: 0.0 ± 0.0
5.53ProPro: 5.53 ± 2.84
0.922ProGln: 0.922 ± 0.631
5.53ProArg: 5.53 ± 0.19
2.765ProSer: 2.765 ± 0.758
1.843ProThr: 1.843 ± 1.388
3.687ProVal: 3.687 ± 1.452
0.922ProTrp: 0.922 ± 0.694
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
2.765GlnAla: 2.765 ± 2.083
0.0GlnCys: 0.0 ± 0.0
0.0GlnAsp: 0.0 ± 0.0
2.765GlnGlu: 2.765 ± 0.758
2.765GlnPhe: 2.765 ± 1.892
0.0GlnGly: 0.0 ± 0.0
0.0GlnHis: 0.0 ± 0.0
2.765GlnIle: 2.765 ± 0.758
1.843GlnLys: 1.843 ± 1.261
3.687GlnLeu: 3.687 ± 1.198
0.0GlnMet: 0.0 ± 0.0
4.608GlnAsn: 4.608 ± 0.821
0.922GlnPro: 0.922 ± 0.694
0.0GlnGln: 0.0 ± 0.0
1.843GlnArg: 1.843 ± 0.063
2.765GlnSer: 2.765 ± 0.567
2.765GlnThr: 2.765 ± 0.567
3.687GlnVal: 3.687 ± 0.127
0.0GlnTrp: 0.0 ± 0.0
1.843GlnTyr: 1.843 ± 0.063
0.0GlnXaa: 0.0 ± 0.0
Arg
7.373ArgAla: 7.373 ± 1.579
1.843ArgCys: 1.843 ± 1.261
5.53ArgAsp: 5.53 ± 2.84
4.608ArgGlu: 4.608 ± 0.504
3.687ArgPhe: 3.687 ± 1.198
4.608ArgGly: 4.608 ± 2.146
3.687ArgHis: 3.687 ± 1.452
3.687ArgIle: 3.687 ± 1.198
2.765ArgLys: 2.765 ± 0.567
8.295ArgLeu: 8.295 ± 4.923
1.843ArgMet: 1.843 ± 0.063
1.843ArgAsn: 1.843 ± 1.261
1.843ArgPro: 1.843 ± 0.063
1.843ArgGln: 1.843 ± 1.388
4.608ArgArg: 4.608 ± 0.504
2.765ArgSer: 2.765 ± 0.567
1.843ArgThr: 1.843 ± 1.261
4.608ArgVal: 4.608 ± 2.146
0.922ArgTrp: 0.922 ± 0.694
3.687ArgTyr: 3.687 ± 0.127
0.0ArgXaa: 0.0 ± 0.0
Ser
1.843SerAla: 1.843 ± 0.063
0.922SerCys: 0.922 ± 0.694
2.765SerAsp: 2.765 ± 0.758
2.765SerGlu: 2.765 ± 1.892
2.765SerPhe: 2.765 ± 1.892
5.53SerGly: 5.53 ± 3.784
2.765SerHis: 2.765 ± 0.758
0.0SerIle: 0.0 ± 0.0
9.217SerLys: 9.217 ± 3.657
5.53SerLeu: 5.53 ± 0.19
2.765SerMet: 2.765 ± 0.404
2.765SerAsn: 2.765 ± 0.758
4.608SerPro: 4.608 ± 0.821
5.53SerGln: 5.53 ± 1.134
2.765SerArg: 2.765 ± 0.758
4.608SerSer: 4.608 ± 0.504
0.0SerThr: 0.0 ± 0.0
1.843SerVal: 1.843 ± 1.388
0.0SerTrp: 0.0 ± 0.0
2.765SerTyr: 2.765 ± 0.567
0.0SerXaa: 0.0 ± 0.0
Thr
4.608ThrAla: 4.608 ± 0.504
1.843ThrCys: 1.843 ± 0.063
3.687ThrAsp: 3.687 ± 1.452
0.922ThrGlu: 0.922 ± 0.631
2.765ThrPhe: 2.765 ± 0.758
3.687ThrGly: 3.687 ± 1.198
0.0ThrHis: 0.0 ± 0.0
2.765ThrIle: 2.765 ± 0.567
1.843ThrLys: 1.843 ± 1.261
4.608ThrLeu: 4.608 ± 1.829
1.843ThrMet: 1.843 ± 0.063
1.843ThrAsn: 1.843 ± 1.261
0.922ThrPro: 0.922 ± 0.631
2.765ThrGln: 2.765 ± 2.083
0.0ThrArg: 0.0 ± 0.0
4.608ThrSer: 4.608 ± 0.504
6.452ThrThr: 6.452 ± 0.44
5.53ThrVal: 5.53 ± 2.459
0.922ThrTrp: 0.922 ± 0.694
4.608ThrTyr: 4.608 ± 0.821
0.0ThrXaa: 0.0 ± 0.0
Val
4.608ValAla: 4.608 ± 0.504
1.843ValCys: 1.843 ± 1.388
6.452ValAsp: 6.452 ± 2.21
4.608ValGlu: 4.608 ± 0.821
1.843ValPhe: 1.843 ± 0.063
1.843ValGly: 1.843 ± 0.063
0.0ValHis: 0.0 ± 0.0
0.922ValIle: 0.922 ± 0.631
6.452ValLys: 6.452 ± 3.09
7.373ValLeu: 7.373 ± 1.579
0.922ValMet: 0.922 ± 0.631
1.843ValAsn: 1.843 ± 0.063
5.53ValPro: 5.53 ± 0.19
3.687ValGln: 3.687 ± 1.198
5.53ValArg: 5.53 ± 4.165
2.765ValSer: 2.765 ± 0.567
2.765ValThr: 2.765 ± 0.758
4.608ValVal: 4.608 ± 3.471
0.0ValTrp: 0.0 ± 0.0
2.765ValTyr: 2.765 ± 0.567
0.0ValXaa: 0.0 ± 0.0
Trp
0.922TrpAla: 0.922 ± 0.694
0.0TrpCys: 0.0 ± 0.0
0.922TrpAsp: 0.922 ± 0.694
0.0TrpGlu: 0.0 ± 0.0
2.765TrpPhe: 2.765 ± 0.758
0.922TrpGly: 0.922 ± 0.694
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
2.765TrpVal: 2.765 ± 0.567
0.0TrpTrp: 0.0 ± 0.0
0.922TrpTyr: 0.922 ± 0.694
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.765TyrAla: 2.765 ± 1.892
0.0TyrCys: 0.0 ± 0.0
1.843TyrAsp: 1.843 ± 1.388
3.687TyrGlu: 3.687 ± 1.198
3.687TyrPhe: 3.687 ± 2.523
2.765TyrGly: 2.765 ± 1.892
1.843TyrHis: 1.843 ± 0.063
2.765TyrIle: 2.765 ± 0.758
2.765TyrLys: 2.765 ± 0.567
3.687TyrLeu: 3.687 ± 1.452
0.0TyrMet: 0.0 ± 0.0
3.687TyrAsn: 3.687 ± 0.127
0.922TyrPro: 0.922 ± 0.694
0.0TyrGln: 0.0 ± 0.0
1.843TyrArg: 1.843 ± 0.063
0.922TyrSer: 0.922 ± 0.631
0.922TyrThr: 0.922 ± 0.694
2.765TyrVal: 2.765 ± 0.567
0.922TyrTrp: 0.922 ± 0.694
2.765TyrTyr: 2.765 ± 1.892
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1086 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski