Amino acid dipepetide frequency for Heterobasidion partitivirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.735AlaAla: 9.735 ± 5.071
1.77AlaCys: 1.77 ± 0.123
3.54AlaAsp: 3.54 ± 0.247
2.655AlaGlu: 2.655 ± 0.813
5.31AlaPhe: 5.31 ± 1.625
8.85AlaGly: 8.85 ± 1.872
0.0AlaHis: 0.0 ± 0.0
5.31AlaIle: 5.31 ± 0.37
2.655AlaLys: 2.655 ± 0.443
5.31AlaLeu: 5.31 ± 1.625
3.54AlaMet: 3.54 ± 1.502
3.54AlaAsn: 3.54 ± 2.757
5.31AlaPro: 5.31 ± 0.885
7.965AlaGln: 7.965 ± 2.438
3.54AlaArg: 3.54 ± 1.502
1.77AlaSer: 1.77 ± 1.379
6.195AlaThr: 6.195 ± 3.57
2.655AlaVal: 2.655 ± 2.068
0.885AlaTrp: 0.885 ± 0.566
2.655AlaTyr: 2.655 ± 0.443
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.885CysPhe: 0.885 ± 0.566
1.77CysGly: 1.77 ± 0.123
0.885CysHis: 0.885 ± 0.566
1.77CysIle: 1.77 ± 0.123
0.0CysLys: 0.0 ± 0.0
0.885CysLeu: 0.885 ± 0.689
0.885CysMet: 0.885 ± 0.566
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.885CysSer: 0.885 ± 0.566
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.54AspAla: 3.54 ± 1.009
0.0AspCys: 0.0 ± 0.0
0.885AspAsp: 0.885 ± 0.566
2.655AspGlu: 2.655 ± 0.443
4.425AspPhe: 4.425 ± 2.83
1.77AspGly: 1.77 ± 0.123
3.54AspHis: 3.54 ± 0.247
0.885AspIle: 0.885 ± 0.566
2.655AspLys: 2.655 ± 1.698
5.31AspLeu: 5.31 ± 0.885
1.77AspMet: 1.77 ± 1.379
0.885AspAsn: 0.885 ± 0.689
5.31AspPro: 5.31 ± 2.141
1.77AspGln: 1.77 ± 0.123
2.655AspArg: 2.655 ± 0.813
4.425AspSer: 4.425 ± 1.575
0.885AspThr: 0.885 ± 0.566
4.425AspVal: 4.425 ± 0.319
2.655AspTrp: 2.655 ± 0.813
4.425AspTyr: 4.425 ± 2.83
0.0AspXaa: 0.0 ± 0.0
Glu
2.655GluAla: 2.655 ± 1.698
0.0GluCys: 0.0 ± 0.0
2.655GluAsp: 2.655 ± 1.698
0.0GluGlu: 0.0 ± 0.0
3.54GluPhe: 3.54 ± 0.247
0.0GluGly: 0.0 ± 0.0
0.885GluHis: 0.885 ± 0.566
1.77GluIle: 1.77 ± 0.123
1.77GluLys: 1.77 ± 1.132
2.655GluLeu: 2.655 ± 0.443
0.0GluMet: 0.0 ± 0.0
2.655GluAsn: 2.655 ± 0.443
1.77GluPro: 1.77 ± 0.123
0.885GluGln: 0.885 ± 0.689
0.0GluArg: 0.0 ± 0.0
0.885GluSer: 0.885 ± 0.689
1.77GluThr: 1.77 ± 0.123
2.655GluVal: 2.655 ± 1.698
1.77GluTrp: 1.77 ± 0.123
2.655GluTyr: 2.655 ± 1.698
0.0GluXaa: 0.0 ± 0.0
Phe
6.195PheAla: 6.195 ± 1.059
0.0PheCys: 0.0 ± 0.0
5.31PheAsp: 5.31 ± 0.885
2.655PheGlu: 2.655 ± 0.443
5.31PhePhe: 5.31 ± 0.885
5.31PheGly: 5.31 ± 0.885
0.885PheHis: 0.885 ± 0.689
3.54PheIle: 3.54 ± 0.247
3.54PheLys: 3.54 ± 2.264
8.85PheLeu: 8.85 ± 1.894
1.77PheMet: 1.77 ± 0.123
0.0PheAsn: 0.0 ± 0.0
2.655PhePro: 2.655 ± 0.443
1.77PheGln: 1.77 ± 1.379
2.655PheArg: 2.655 ± 1.698
6.195PheSer: 6.195 ± 0.196
6.195PheThr: 6.195 ± 0.196
0.885PheVal: 0.885 ± 0.566
1.77PheTrp: 1.77 ± 0.123
1.77PheTyr: 1.77 ± 0.123
0.0PheXaa: 0.0 ± 0.0
Gly
4.425GlyAla: 4.425 ± 2.191
0.0GlyCys: 0.0 ± 0.0
3.54GlyAsp: 3.54 ± 2.264
1.77GlyGlu: 1.77 ± 0.123
3.54GlyPhe: 3.54 ± 1.009
0.885GlyGly: 0.885 ± 0.566
0.885GlyHis: 0.885 ± 0.566
1.77GlyIle: 1.77 ± 1.132
0.0GlyLys: 0.0 ± 0.0
5.31GlyLeu: 5.31 ± 2.141
0.885GlyMet: 0.885 ± 0.689
3.54GlyAsn: 3.54 ± 1.502
4.425GlyPro: 4.425 ± 3.446
1.77GlyGln: 1.77 ± 1.379
2.655GlyArg: 2.655 ± 2.068
2.655GlySer: 2.655 ± 1.698
2.655GlyThr: 2.655 ± 0.813
2.655GlyVal: 2.655 ± 0.813
0.885GlyTrp: 0.885 ± 0.566
5.31GlyTyr: 5.31 ± 0.885
0.0GlyXaa: 0.0 ± 0.0
His
2.655HisAla: 2.655 ± 2.068
0.0HisCys: 0.0 ± 0.0
0.885HisAsp: 0.885 ± 0.566
1.77HisGlu: 1.77 ± 1.132
2.655HisPhe: 2.655 ± 0.813
0.885HisGly: 0.885 ± 0.689
0.0HisHis: 0.0 ± 0.0
2.655HisIle: 2.655 ± 0.443
0.885HisLys: 0.885 ± 0.566
4.425HisLeu: 4.425 ± 0.936
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
1.77HisPro: 1.77 ± 0.123
0.0HisGln: 0.0 ± 0.0
1.77HisArg: 1.77 ± 1.379
2.655HisSer: 2.655 ± 1.698
5.31HisThr: 5.31 ± 0.37
1.77HisVal: 1.77 ± 0.123
0.885HisTrp: 0.885 ± 0.689
2.655HisTyr: 2.655 ± 1.698
0.0HisXaa: 0.0 ± 0.0
Ile
2.655IleAla: 2.655 ± 0.813
0.0IleCys: 0.0 ± 0.0
3.54IleAsp: 3.54 ± 0.247
2.655IleGlu: 2.655 ± 1.698
3.54IlePhe: 3.54 ± 0.247
2.655IleGly: 2.655 ± 0.443
0.885IleHis: 0.885 ± 0.566
2.655IleIle: 2.655 ± 1.698
4.425IleLys: 4.425 ± 2.83
3.54IleLeu: 3.54 ± 1.502
2.655IleMet: 2.655 ± 1.141
2.655IleAsn: 2.655 ± 2.068
2.655IlePro: 2.655 ± 1.698
2.655IleGln: 2.655 ± 0.443
2.655IleArg: 2.655 ± 1.698
7.965IleSer: 7.965 ± 1.182
6.195IleThr: 6.195 ± 1.451
3.54IleVal: 3.54 ± 1.009
0.885IleTrp: 0.885 ± 0.566
1.77IleTyr: 1.77 ± 0.123
0.0IleXaa: 0.0 ± 0.0
Lys
1.77LysAla: 1.77 ± 1.132
0.0LysCys: 0.0 ± 0.0
2.655LysAsp: 2.655 ± 0.443
0.0LysGlu: 0.0 ± 0.0
1.77LysPhe: 1.77 ± 1.132
0.885LysGly: 0.885 ± 0.689
0.885LysHis: 0.885 ± 0.689
2.655LysIle: 2.655 ± 1.698
0.885LysLys: 0.885 ± 0.566
5.31LysLeu: 5.31 ± 2.141
0.885LysMet: 0.885 ± 0.386
0.885LysAsn: 0.885 ± 0.566
0.885LysPro: 0.885 ± 0.566
0.0LysGln: 0.0 ± 0.0
3.54LysArg: 3.54 ± 2.264
3.54LysSer: 3.54 ± 1.009
0.885LysThr: 0.885 ± 0.566
1.77LysVal: 1.77 ± 1.132
0.885LysTrp: 0.885 ± 0.566
2.655LysTyr: 2.655 ± 0.443
0.0LysXaa: 0.0 ± 0.0
Leu
9.735LeuAla: 9.735 ± 5.071
0.0LeuCys: 0.0 ± 0.0
6.195LeuAsp: 6.195 ± 1.451
0.885LeuGlu: 0.885 ± 0.689
6.195LeuPhe: 6.195 ± 2.707
3.54LeuGly: 3.54 ± 2.757
7.08LeuHis: 7.08 ± 0.762
3.54LeuIle: 3.54 ± 2.264
0.885LeuLys: 0.885 ± 0.689
6.195LeuLeu: 6.195 ± 1.059
0.885LeuMet: 0.885 ± 0.566
3.54LeuAsn: 3.54 ± 0.247
8.85LeuPro: 8.85 ± 4.382
1.77LeuGln: 1.77 ± 1.132
7.08LeuArg: 7.08 ± 4.528
9.735LeuSer: 9.735 ± 3.816
2.655LeuThr: 2.655 ± 1.698
1.77LeuVal: 1.77 ± 1.379
5.31LeuTrp: 5.31 ± 2.141
3.54LeuTyr: 3.54 ± 1.009
0.0LeuXaa: 0.0 ± 0.0
Met
1.77MetAla: 1.77 ± 0.123
0.0MetCys: 0.0 ± 0.0
3.54MetAsp: 3.54 ± 1.009
0.885MetGlu: 0.885 ± 0.689
0.885MetPhe: 0.885 ± 0.566
0.885MetGly: 0.885 ± 0.566
0.0MetHis: 0.0 ± 0.0
2.655MetIle: 2.655 ± 0.443
0.885MetLys: 0.885 ± 0.566
4.425MetLeu: 4.425 ± 1.575
0.885MetMet: 0.885 ± 0.689
0.885MetAsn: 0.885 ± 0.689
3.54MetPro: 3.54 ± 2.757
1.77MetGln: 1.77 ± 0.123
0.0MetArg: 0.0 ± 0.0
0.885MetSer: 0.885 ± 0.689
2.655MetThr: 2.655 ± 2.068
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
8.85AsnAla: 8.85 ± 3.127
0.0AsnCys: 0.0 ± 0.0
1.77AsnAsp: 1.77 ± 0.123
0.885AsnGlu: 0.885 ± 0.566
3.54AsnPhe: 3.54 ± 0.247
2.655AsnGly: 2.655 ± 0.443
1.77AsnHis: 1.77 ± 0.123
2.655AsnIle: 2.655 ± 0.813
0.885AsnLys: 0.885 ± 0.566
4.425AsnLeu: 4.425 ± 0.936
0.0AsnMet: 0.0 ± 0.0
3.54AsnAsn: 3.54 ± 2.757
2.655AsnPro: 2.655 ± 1.698
0.885AsnGln: 0.885 ± 0.566
2.655AsnArg: 2.655 ± 0.813
1.77AsnSer: 1.77 ± 0.123
2.655AsnThr: 2.655 ± 2.068
3.54AsnVal: 3.54 ± 2.757
0.885AsnTrp: 0.885 ± 0.689
1.77AsnTyr: 1.77 ± 0.123
0.0AsnXaa: 0.0 ± 0.0
Pro
6.195ProAla: 6.195 ± 0.196
0.885ProCys: 0.885 ± 0.566
5.31ProAsp: 5.31 ± 0.885
2.655ProGlu: 2.655 ± 0.443
2.655ProPhe: 2.655 ± 0.443
5.31ProGly: 5.31 ± 1.625
0.0ProHis: 0.0 ± 0.0
5.31ProIle: 5.31 ± 1.625
0.885ProLys: 0.885 ± 0.566
5.31ProLeu: 5.31 ± 1.625
3.54ProMet: 3.54 ± 0.247
5.31ProAsn: 5.31 ± 1.625
4.425ProPro: 4.425 ± 0.319
4.425ProGln: 4.425 ± 2.191
2.655ProArg: 2.655 ± 0.813
7.08ProSer: 7.08 ± 0.762
5.31ProThr: 5.31 ± 0.885
1.77ProVal: 1.77 ± 0.123
0.0ProTrp: 0.0 ± 0.0
0.885ProTyr: 0.885 ± 0.566
0.0ProXaa: 0.0 ± 0.0
Gln
3.54GlnAla: 3.54 ± 0.247
0.885GlnCys: 0.885 ± 0.566
0.0GlnAsp: 0.0 ± 0.0
1.77GlnGlu: 1.77 ± 1.132
3.54GlnPhe: 3.54 ± 1.502
2.655GlnGly: 2.655 ± 1.698
1.77GlnHis: 1.77 ± 0.123
1.77GlnIle: 1.77 ± 0.123
0.0GlnLys: 0.0 ± 0.0
3.54GlnLeu: 3.54 ± 0.247
0.885GlnMet: 0.885 ± 0.566
0.885GlnAsn: 0.885 ± 0.689
2.655GlnPro: 2.655 ± 0.813
0.0GlnGln: 0.0 ± 0.0
3.54GlnArg: 3.54 ± 0.247
0.0GlnSer: 0.0 ± 0.0
2.655GlnThr: 2.655 ± 2.068
7.965GlnVal: 7.965 ± 2.438
0.885GlnTrp: 0.885 ± 0.566
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
2.655ArgAla: 2.655 ± 0.813
1.77ArgCys: 1.77 ± 1.132
2.655ArgAsp: 2.655 ± 0.443
0.0ArgGlu: 0.0 ± 0.0
5.31ArgPhe: 5.31 ± 0.885
0.885ArgGly: 0.885 ± 0.689
2.655ArgHis: 2.655 ± 0.813
3.54ArgIle: 3.54 ± 0.247
2.655ArgLys: 2.655 ± 1.698
4.425ArgLeu: 4.425 ± 0.319
0.885ArgMet: 0.885 ± 0.566
4.425ArgAsn: 4.425 ± 0.319
3.54ArgPro: 3.54 ± 1.502
1.77ArgGln: 1.77 ± 0.123
2.655ArgArg: 2.655 ± 0.443
3.54ArgSer: 3.54 ± 0.247
6.195ArgThr: 6.195 ± 1.451
1.77ArgVal: 1.77 ± 1.132
0.0ArgTrp: 0.0 ± 0.0
0.885ArgTyr: 0.885 ± 0.566
0.0ArgXaa: 0.0 ± 0.0
Ser
3.54SerAla: 3.54 ± 2.757
0.885SerCys: 0.885 ± 0.689
1.77SerAsp: 1.77 ± 1.132
3.54SerGlu: 3.54 ± 1.009
5.31SerPhe: 5.31 ± 0.885
2.655SerGly: 2.655 ± 0.443
2.655SerHis: 2.655 ± 0.813
5.31SerIle: 5.31 ± 0.885
2.655SerLys: 2.655 ± 0.813
8.85SerLeu: 8.85 ± 4.382
0.885SerMet: 0.885 ± 0.566
2.655SerAsn: 2.655 ± 0.443
4.425SerPro: 4.425 ± 0.319
2.655SerGln: 2.655 ± 0.443
5.31SerArg: 5.31 ± 2.141
5.31SerSer: 5.31 ± 2.88
8.85SerThr: 8.85 ± 0.617
0.885SerVal: 0.885 ± 0.566
1.77SerTrp: 1.77 ± 1.132
1.77SerTyr: 1.77 ± 0.123
0.0SerXaa: 0.0 ± 0.0
Thr
6.195ThrAla: 6.195 ± 3.57
0.885ThrCys: 0.885 ± 0.689
3.54ThrAsp: 3.54 ± 1.009
3.54ThrGlu: 3.54 ± 1.009
2.655ThrPhe: 2.655 ± 0.813
2.655ThrGly: 2.655 ± 0.443
2.655ThrHis: 2.655 ± 0.813
5.31ThrIle: 5.31 ± 0.37
5.31ThrLys: 5.31 ± 0.885
2.655ThrLeu: 2.655 ± 0.443
2.655ThrMet: 2.655 ± 0.443
6.195ThrAsn: 6.195 ± 1.059
7.08ThrPro: 7.08 ± 2.017
1.77ThrGln: 1.77 ± 0.123
1.77ThrArg: 1.77 ± 0.123
7.08ThrSer: 7.08 ± 1.748
0.885ThrThr: 0.885 ± 0.689
5.31ThrVal: 5.31 ± 2.88
0.885ThrTrp: 0.885 ± 0.566
3.54ThrTyr: 3.54 ± 1.009
0.0ThrXaa: 0.0 ± 0.0
Val
5.31ValAla: 5.31 ± 2.88
0.885ValCys: 0.885 ± 0.566
1.77ValAsp: 1.77 ± 1.379
0.0ValGlu: 0.0 ± 0.0
1.77ValPhe: 1.77 ± 0.123
0.0ValGly: 0.0 ± 0.0
1.77ValHis: 1.77 ± 0.123
2.655ValIle: 2.655 ± 0.813
0.885ValLys: 0.885 ± 0.689
4.425ValLeu: 4.425 ± 0.319
0.885ValMet: 0.885 ± 0.689
4.425ValAsn: 4.425 ± 1.575
2.655ValPro: 2.655 ± 2.068
3.54ValGln: 3.54 ± 1.009
2.655ValArg: 2.655 ± 2.068
4.425ValSer: 4.425 ± 1.575
6.195ValThr: 6.195 ± 0.196
0.885ValVal: 0.885 ± 0.566
0.0ValTrp: 0.0 ± 0.0
0.885ValTyr: 0.885 ± 0.566
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.885TrpAsp: 0.885 ± 0.689
1.77TrpGlu: 1.77 ± 1.132
2.655TrpPhe: 2.655 ± 0.813
1.77TrpGly: 1.77 ± 1.132
1.77TrpHis: 1.77 ± 0.123
1.77TrpIle: 1.77 ± 1.132
0.0TrpLys: 0.0 ± 0.0
0.885TrpLeu: 0.885 ± 0.566
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.885TrpPro: 0.885 ± 0.566
1.77TrpGln: 1.77 ± 1.132
1.77TrpArg: 1.77 ± 0.123
0.885TrpSer: 0.885 ± 0.566
2.655TrpThr: 2.655 ± 0.443
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
1.77TrpTyr: 1.77 ± 0.123
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.77TyrAla: 1.77 ± 1.132
0.0TyrCys: 0.0 ± 0.0
4.425TyrAsp: 4.425 ± 1.575
0.885TyrGlu: 0.885 ± 0.566
1.77TyrPhe: 1.77 ± 1.132
3.54TyrGly: 3.54 ± 0.247
2.655TyrHis: 2.655 ± 0.443
2.655TyrIle: 2.655 ± 1.698
1.77TyrLys: 1.77 ± 1.132
2.655TyrLeu: 2.655 ± 0.443
1.77TyrMet: 1.77 ± 0.123
1.77TyrAsn: 1.77 ± 0.123
4.425TyrPro: 4.425 ± 0.319
1.77TyrGln: 1.77 ± 0.123
2.655TyrArg: 2.655 ± 1.698
0.0TyrSer: 0.0 ± 0.0
1.77TyrThr: 1.77 ± 0.123
1.77TyrVal: 1.77 ± 1.132
0.885TyrTrp: 0.885 ± 0.566
4.425TyrTyr: 4.425 ± 2.191
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1131 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski