Amino acid dipepetide frequency for Arenimonas oryziterrae DSM 21050 = YC6267

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
16.691AlaAla: 16.691 ± 0.19
1.236AlaCys: 1.236 ± 0.041
7.188AlaAsp: 7.188 ± 0.098
7.083AlaGlu: 7.083 ± 0.105
4.209AlaPhe: 4.209 ± 0.073
10.467AlaGly: 10.467 ± 0.129
2.576AlaHis: 2.576 ± 0.056
5.699AlaIle: 5.699 ± 0.077
3.948AlaLys: 3.948 ± 0.089
14.955AlaLeu: 14.955 ± 0.161
3.439AlaMet: 3.439 ± 0.062
3.089AlaAsn: 3.089 ± 0.074
6.303AlaPro: 6.303 ± 0.111
5.116AlaGln: 5.116 ± 0.083
9.105AlaArg: 9.105 ± 0.111
6.368AlaSer: 6.368 ± 0.083
6.491AlaThr: 6.491 ± 0.121
8.272AlaVal: 8.272 ± 0.105
1.943AlaTrp: 1.943 ± 0.047
2.458AlaTyr: 2.458 ± 0.046
0.0AlaXaa: 0.0 ± 0.0
Cys
1.064CysAla: 1.064 ± 0.036
0.104CysCys: 0.104 ± 0.011
0.477CysAsp: 0.477 ± 0.024
0.517CysGlu: 0.517 ± 0.023
0.352CysPhe: 0.352 ± 0.017
0.857CysGly: 0.857 ± 0.032
0.245CysHis: 0.245 ± 0.017
0.304CysIle: 0.304 ± 0.018
0.208CysLys: 0.208 ± 0.014
0.947CysLeu: 0.947 ± 0.036
0.12CysMet: 0.12 ± 0.009
0.204CysAsn: 0.204 ± 0.014
0.458CysPro: 0.458 ± 0.026
0.272CysGln: 0.272 ± 0.017
0.626CysArg: 0.626 ± 0.031
0.44CysSer: 0.44 ± 0.021
0.428CysThr: 0.428 ± 0.024
0.682CysVal: 0.682 ± 0.026
0.118CysTrp: 0.118 ± 0.016
0.204CysTyr: 0.204 ± 0.015
0.0CysXaa: 0.0 ± 0.0
Asp
8.001AspAla: 8.001 ± 0.105
0.509AspCys: 0.509 ± 0.026
3.063AspAsp: 3.063 ± 0.063
3.381AspGlu: 3.381 ± 0.056
2.278AspPhe: 2.278 ± 0.045
5.369AspGly: 5.369 ± 0.094
1.123AspHis: 1.123 ± 0.039
2.633AspIle: 2.633 ± 0.05
1.712AspLys: 1.712 ± 0.052
5.835AspLeu: 5.835 ± 0.087
1.033AspMet: 1.033 ± 0.035
1.326AspAsn: 1.326 ± 0.04
3.279AspPro: 3.279 ± 0.062
1.71AspGln: 1.71 ± 0.046
4.048AspArg: 4.048 ± 0.073
2.545AspSer: 2.545 ± 0.062
2.745AspThr: 2.745 ± 0.06
4.074AspVal: 4.074 ± 0.069
1.094AspTrp: 1.094 ± 0.034
1.742AspTyr: 1.742 ± 0.043
0.0AspXaa: 0.0 ± 0.0
Glu
6.839GluAla: 6.839 ± 0.1
0.364GluCys: 0.364 ± 0.021
2.581GluAsp: 2.581 ± 0.056
2.572GluGlu: 2.572 ± 0.061
2.001GluPhe: 2.001 ± 0.047
3.831GluGly: 3.831 ± 0.067
1.449GluHis: 1.449 ± 0.039
2.833GluIle: 2.833 ± 0.067
1.971GluLys: 1.971 ± 0.05
6.069GluLeu: 6.069 ± 0.096
1.212GluMet: 1.212 ± 0.038
1.454GluAsn: 1.454 ± 0.041
2.434GluPro: 2.434 ± 0.058
2.406GluGln: 2.406 ± 0.065
4.986GluArg: 4.986 ± 0.085
2.75GluSer: 2.75 ± 0.062
2.893GluThr: 2.893 ± 0.061
3.791GluVal: 3.791 ± 0.065
0.701GluTrp: 0.701 ± 0.028
1.07GluTyr: 1.07 ± 0.037
0.0GluXaa: 0.0 ± 0.0
Phe
4.58PheAla: 4.58 ± 0.075
0.362PheCys: 0.362 ± 0.02
2.765PheAsp: 2.765 ± 0.055
2.123PheGlu: 2.123 ± 0.052
1.412PhePhe: 1.412 ± 0.04
3.49PheGly: 3.49 ± 0.071
0.756PheHis: 0.756 ± 0.033
1.343PheIle: 1.343 ± 0.041
0.979PheLys: 0.979 ± 0.035
3.498PheLeu: 3.498 ± 0.063
0.637PheMet: 0.637 ± 0.026
1.101PheAsn: 1.101 ± 0.034
1.527PhePro: 1.527 ± 0.041
0.987PheGln: 0.987 ± 0.033
2.238PheArg: 2.238 ± 0.052
2.227PheSer: 2.227 ± 0.05
1.807PheThr: 1.807 ± 0.053
2.897PheVal: 2.897 ± 0.07
0.519PheTrp: 0.519 ± 0.027
0.891PheTyr: 0.891 ± 0.031
0.0PheXaa: 0.0 ± 0.0
Gly
8.47GlyAla: 8.47 ± 0.106
0.772GlyCys: 0.772 ± 0.027
4.777GlyAsp: 4.777 ± 0.08
4.965GlyGlu: 4.965 ± 0.078
3.44GlyPhe: 3.44 ± 0.074
6.669GlyGly: 6.669 ± 0.125
1.967GlyHis: 1.967 ± 0.054
3.893GlyIle: 3.893 ± 0.081
3.514GlyLys: 3.514 ± 0.067
9.177GlyLeu: 9.177 ± 0.103
2.048GlyMet: 2.048 ± 0.054
2.341GlyAsn: 2.341 ± 0.064
3.125GlyPro: 3.125 ± 0.061
3.15GlyGln: 3.15 ± 0.061
5.779GlyArg: 5.779 ± 0.081
4.534GlySer: 4.534 ± 0.077
4.227GlyThr: 4.227 ± 0.094
6.165GlyVal: 6.165 ± 0.086
1.46GlyTrp: 1.46 ± 0.044
2.421GlyTyr: 2.421 ± 0.055
0.0GlyXaa: 0.0 ± 0.0
His
2.739HisAla: 2.739 ± 0.058
0.264HisCys: 0.264 ± 0.016
1.183HisAsp: 1.183 ± 0.039
1.17HisGlu: 1.17 ± 0.035
0.891HisPhe: 0.891 ± 0.032
2.112HisGly: 2.112 ± 0.05
0.598HisHis: 0.598 ± 0.025
0.792HisIle: 0.792 ± 0.026
0.507HisLys: 0.507 ± 0.021
2.251HisLeu: 2.251 ± 0.058
0.433HisMet: 0.433 ± 0.021
0.461HisAsn: 0.461 ± 0.022
1.398HisPro: 1.398 ± 0.038
0.621HisGln: 0.621 ± 0.027
1.691HisArg: 1.691 ± 0.047
1.016HisSer: 1.016 ± 0.033
0.934HisThr: 0.934 ± 0.03
1.552HisVal: 1.552 ± 0.042
0.441HisTrp: 0.441 ± 0.023
0.644HisTyr: 0.644 ± 0.028
0.0HisXaa: 0.0 ± 0.0
Ile
6.967IleAla: 6.967 ± 0.078
0.393IleCys: 0.393 ± 0.021
3.276IleAsp: 3.276 ± 0.06
3.178IleGlu: 3.178 ± 0.065
1.274IlePhe: 1.274 ± 0.039
4.458IleGly: 4.458 ± 0.074
0.85IleHis: 0.85 ± 0.032
1.519IleIle: 1.519 ± 0.044
1.313IleLys: 1.313 ± 0.042
3.552IleLeu: 3.552 ± 0.066
0.589IleMet: 0.589 ± 0.026
1.361IleAsn: 1.361 ± 0.041
2.101IlePro: 2.101 ± 0.04
1.115IleGln: 1.115 ± 0.038
2.768IleArg: 2.768 ± 0.059
2.338IleSer: 2.338 ± 0.05
2.472IleThr: 2.472 ± 0.058
3.604IleVal: 3.604 ± 0.069
0.464IleTrp: 0.464 ± 0.025
0.996IleTyr: 0.996 ± 0.03
0.0IleXaa: 0.0 ± 0.0
Lys
3.576LysAla: 3.576 ± 0.08
0.147LysCys: 0.147 ± 0.014
1.721LysAsp: 1.721 ± 0.051
1.38LysGlu: 1.38 ± 0.043
0.956LysPhe: 0.956 ± 0.036
2.076LysGly: 2.076 ± 0.049
0.683LysHis: 0.683 ± 0.029
1.543LysIle: 1.543 ± 0.046
1.389LysLys: 1.389 ± 0.054
3.378LysLeu: 3.378 ± 0.066
0.726LysMet: 0.726 ± 0.028
0.924LysAsn: 0.924 ± 0.034
2.178LysPro: 2.178 ± 0.058
1.264LysGln: 1.264 ± 0.036
2.29LysArg: 2.29 ± 0.054
1.573LysSer: 1.573 ± 0.043
1.752LysThr: 1.752 ± 0.046
2.189LysVal: 2.189 ± 0.053
0.308LysTrp: 0.308 ± 0.018
0.742LysTyr: 0.742 ± 0.03
0.0LysXaa: 0.0 ± 0.0
Leu
15.715LeuAla: 15.715 ± 0.182
0.978LeuCys: 0.978 ± 0.033
6.476LeuAsp: 6.476 ± 0.102
5.211LeuGlu: 5.211 ± 0.086
3.584LeuPhe: 3.584 ± 0.067
8.781LeuGly: 8.781 ± 0.109
2.362LeuHis: 2.362 ± 0.049
4.913LeuIle: 4.913 ± 0.078
3.31LeuLys: 3.31 ± 0.066
11.778LeuLeu: 11.778 ± 0.158
2.296LeuMet: 2.296 ± 0.05
2.493LeuAsn: 2.493 ± 0.058
6.603LeuPro: 6.603 ± 0.101
3.655LeuGln: 3.655 ± 0.061
8.744LeuArg: 8.744 ± 0.104
6.552LeuSer: 6.552 ± 0.094
5.338LeuThr: 5.338 ± 0.07
7.889LeuVal: 7.889 ± 0.092
1.496LeuTrp: 1.496 ± 0.046
2.156LeuTyr: 2.156 ± 0.051
0.0LeuXaa: 0.0 ± 0.0
Met
2.519MetAla: 2.519 ± 0.049
0.137MetCys: 0.137 ± 0.011
1.096MetAsp: 1.096 ± 0.037
0.872MetGlu: 0.872 ± 0.03
0.693MetPhe: 0.693 ± 0.035
1.509MetGly: 1.509 ± 0.04
0.473MetHis: 0.473 ± 0.022
1.068MetIle: 1.068 ± 0.031
0.903MetLys: 0.903 ± 0.03
2.415MetLeu: 2.415 ± 0.045
0.532MetMet: 0.532 ± 0.024
0.767MetAsn: 0.767 ± 0.027
1.327MetPro: 1.327 ± 0.032
0.895MetGln: 0.895 ± 0.033
1.695MetArg: 1.695 ± 0.039
1.624MetSer: 1.624 ± 0.043
1.494MetThr: 1.494 ± 0.038
1.397MetVal: 1.397 ± 0.045
0.197MetTrp: 0.197 ± 0.014
0.365MetTyr: 0.365 ± 0.022
0.0MetXaa: 0.0 ± 0.0
Asn
3.41AsnAla: 3.41 ± 0.075
0.244AsnCys: 0.244 ± 0.019
1.47AsnAsp: 1.47 ± 0.044
1.303AsnGlu: 1.303 ± 0.038
0.98AsnPhe: 0.98 ± 0.036
2.362AsnGly: 2.362 ± 0.06
0.535AsnHis: 0.535 ± 0.028
1.166AsnIle: 1.166 ± 0.044
0.725AsnLys: 0.725 ± 0.032
2.7AsnLeu: 2.7 ± 0.054
0.402AsnMet: 0.402 ± 0.022
0.769AsnAsn: 0.769 ± 0.04
1.789AsnPro: 1.789 ± 0.044
0.786AsnGln: 0.786 ± 0.034
1.779AsnArg: 1.779 ± 0.044
1.188AsnSer: 1.188 ± 0.041
1.399AsnThr: 1.399 ± 0.052
1.799AsnVal: 1.799 ± 0.044
0.376AsnTrp: 0.376 ± 0.022
0.735AsnTyr: 0.735 ± 0.033
0.0AsnXaa: 0.0 ± 0.0
Pro
7.242ProAla: 7.242 ± 0.127
0.323ProCys: 0.323 ± 0.02
3.507ProAsp: 3.507 ± 0.068
3.395ProGlu: 3.395 ± 0.061
1.673ProPhe: 1.673 ± 0.046
4.753ProGly: 4.753 ± 0.081
0.911ProHis: 0.911 ± 0.034
2.081ProIle: 2.081 ± 0.047
1.547ProLys: 1.547 ± 0.051
5.115ProLeu: 5.115 ± 0.082
1.454ProMet: 1.454 ± 0.041
1.276ProAsn: 1.276 ± 0.036
2.859ProPro: 2.859 ± 0.086
1.729ProGln: 1.729 ± 0.041
3.212ProArg: 3.212 ± 0.069
2.609ProSer: 2.609 ± 0.056
2.746ProThr: 2.746 ± 0.062
4.493ProVal: 4.493 ± 0.08
0.807ProTrp: 0.807 ± 0.03
1.133ProTyr: 1.133 ± 0.032
0.0ProXaa: 0.0 ± 0.0
Gln
5.083GlnAla: 5.083 ± 0.085
0.233GlnCys: 0.233 ± 0.017
1.43GlnAsp: 1.43 ± 0.044
1.373GlnGlu: 1.373 ± 0.042
1.196GlnPhe: 1.196 ± 0.034
2.706GlnGly: 2.706 ± 0.053
0.768GlnHis: 0.768 ± 0.031
1.692GlnIle: 1.692 ± 0.042
1.007GlnLys: 1.007 ± 0.039
4.014GlnLeu: 4.014 ± 0.067
0.848GlnMet: 0.848 ± 0.031
0.762GlnAsn: 0.762 ± 0.029
1.938GlnPro: 1.938 ± 0.046
1.568GlnGln: 1.568 ± 0.046
3.362GlnArg: 3.362 ± 0.066
1.862GlnSer: 1.862 ± 0.048
1.826GlnThr: 1.826 ± 0.048
2.872GlnVal: 2.872 ± 0.054
0.564GlnTrp: 0.564 ± 0.029
0.727GlnTyr: 0.727 ± 0.027
0.0GlnXaa: 0.0 ± 0.0
Arg
8.229ArgAla: 8.229 ± 0.119
0.61ArgCys: 0.61 ± 0.025
4.496ArgAsp: 4.496 ± 0.074
4.754ArgGlu: 4.754 ± 0.082
3.023ArgPhe: 3.023 ± 0.054
5.158ArgGly: 5.158 ± 0.075
1.754ArgHis: 1.754 ± 0.045
3.73ArgIle: 3.73 ± 0.068
2.056ArgLys: 2.056 ± 0.052
8.865ArgLeu: 8.865 ± 0.123
1.793ArgMet: 1.793 ± 0.043
1.887ArgAsn: 1.887 ± 0.046
3.329ArgPro: 3.329 ± 0.06
2.902ArgGln: 2.902 ± 0.061
5.737ArgArg: 5.737 ± 0.092
3.481ArgSer: 3.481 ± 0.058
3.193ArgThr: 3.193 ± 0.062
5.391ArgVal: 5.391 ± 0.074
1.352ArgTrp: 1.352 ± 0.031
2.158ArgTyr: 2.158 ± 0.05
0.0ArgXaa: 0.0 ± 0.0
Ser
6.323SerAla: 6.323 ± 0.082
0.424SerCys: 0.424 ± 0.025
2.9SerAsp: 2.9 ± 0.06
2.852SerGlu: 2.852 ± 0.06
2.116SerPhe: 2.116 ± 0.051
5.059SerGly: 5.059 ± 0.086
1.096SerHis: 1.096 ± 0.031
2.087SerIle: 2.087 ± 0.053
1.566SerLys: 1.566 ± 0.045
6.046SerLeu: 6.046 ± 0.088
1.056SerMet: 1.056 ± 0.037
1.388SerAsn: 1.388 ± 0.044
2.902SerPro: 2.902 ± 0.056
1.835SerGln: 1.835 ± 0.048
3.595SerArg: 3.595 ± 0.065
2.789SerSer: 2.789 ± 0.069
2.652SerThr: 2.652 ± 0.057
3.887SerVal: 3.887 ± 0.069
0.777SerTrp: 0.777 ± 0.027
1.391SerTyr: 1.391 ± 0.044
0.0SerXaa: 0.0 ± 0.0
Thr
6.042ThrAla: 6.042 ± 0.104
0.472ThrCys: 0.472 ± 0.028
2.755ThrAsp: 2.755 ± 0.061
2.367ThrGlu: 2.367 ± 0.054
1.618ThrPhe: 1.618 ± 0.047
4.811ThrGly: 4.811 ± 0.083
1.137ThrHis: 1.137 ± 0.035
2.317ThrIle: 2.317 ± 0.061
1.092ThrLys: 1.092 ± 0.04
6.215ThrLeu: 6.215 ± 0.085
1.02ThrMet: 1.02 ± 0.035
1.177ThrAsn: 1.177 ± 0.048
3.644ThrPro: 3.644 ± 0.086
1.74ThrGln: 1.74 ± 0.047
3.596ThrArg: 3.596 ± 0.067
2.456ThrSer: 2.456 ± 0.06
2.851ThrThr: 2.851 ± 0.09
4.091ThrVal: 4.091 ± 0.087
0.684ThrTrp: 0.684 ± 0.029
1.187ThrTyr: 1.187 ± 0.054
0.0ThrXaa: 0.0 ± 0.0
Val
9.133ValAla: 9.133 ± 0.089
0.691ValCys: 0.691 ± 0.027
4.325ValAsp: 4.325 ± 0.068
4.001ValGlu: 4.001 ± 0.071
2.827ValPhe: 2.827 ± 0.06
5.408ValGly: 5.408 ± 0.08
1.599ValHis: 1.599 ± 0.041
3.523ValIle: 3.523 ± 0.06
2.04ValLys: 2.04 ± 0.053
8.573ValLeu: 8.573 ± 0.11
1.604ValMet: 1.604 ± 0.046
2.021ValAsn: 2.021 ± 0.054
3.7ValPro: 3.7 ± 0.065
2.41ValGln: 2.41 ± 0.054
5.115ValArg: 5.115 ± 0.077
4.182ValSer: 4.182 ± 0.075
3.921ValThr: 3.921 ± 0.103
5.887ValVal: 5.887 ± 0.096
0.91ValTrp: 0.91 ± 0.034
1.64ValTyr: 1.64 ± 0.041
0.0ValXaa: 0.0 ± 0.0
Trp
1.19TrpAla: 1.19 ± 0.037
0.157TrpCys: 0.157 ± 0.015
0.666TrpAsp: 0.666 ± 0.028
0.493TrpGlu: 0.493 ± 0.023
0.628TrpPhe: 0.628 ± 0.026
0.876TrpGly: 0.876 ± 0.032
0.336TrpHis: 0.336 ± 0.019
0.747TrpIle: 0.747 ± 0.031
0.469TrpLys: 0.469 ± 0.021
2.253TrpLeu: 2.253 ± 0.064
0.366TrpMet: 0.366 ± 0.019
0.443TrpAsn: 0.443 ± 0.022
0.826TrpPro: 0.826 ± 0.03
0.788TrpGln: 0.788 ± 0.029
1.39TrpArg: 1.39 ± 0.046
0.912TrpSer: 0.912 ± 0.032
0.788TrpThr: 0.788 ± 0.033
0.923TrpVal: 0.923 ± 0.042
0.297TrpTrp: 0.297 ± 0.017
0.358TrpTyr: 0.358 ± 0.021
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.821TyrAla: 2.821 ± 0.052
0.207TyrCys: 0.207 ± 0.013
1.348TyrAsp: 1.348 ± 0.052
1.218TyrGlu: 1.218 ± 0.033
0.988TyrPhe: 0.988 ± 0.032
2.141TyrGly: 2.141 ± 0.059
0.482TyrHis: 0.482 ± 0.023
0.702TyrIle: 0.702 ± 0.028
0.539TyrLys: 0.539 ± 0.026
2.693TyrLeu: 2.693 ± 0.054
0.371TyrMet: 0.371 ± 0.019
0.67TyrAsn: 0.67 ± 0.033
1.145TyrPro: 1.145 ± 0.034
0.883TyrGln: 0.883 ± 0.03
2.14TyrArg: 2.14 ± 0.042
1.294TyrSer: 1.294 ± 0.041
1.317TyrThr: 1.317 ± 0.045
1.657TyrVal: 1.657 ± 0.045
0.402TyrTrp: 0.402 ± 0.022
0.648TyrTyr: 0.648 ± 0.028
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2897 proteins (942598 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski