Amino acid dipepetide frequency for Lipomyces starkeyi NRRL Y-11557

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.631AlaAla: 7.631 ± 0.068	0.958AlaCys: 0.958 ± 0.02	4.038AlaAsp: 4.038 ± 0.034	4.683AlaGlu: 4.683 ± 0.043	3.103AlaPhe: 3.103 ± 0.032	4.855AlaGly: 4.855 ± 0.045	1.577AlaHis: 1.577 ± 0.025	4.756AlaIle: 4.756 ± 0.045	4.04AlaLys: 4.04 ± 0.036	7.284AlaLeu: 7.284 ± 0.055	1.874AlaMet: 1.874 ± 0.027	2.984AlaAsn: 2.984 ± 0.032	3.811AlaPro: 3.811 ± 0.04	2.84AlaGln: 2.84 ± 0.035	4.341AlaArg: 4.341 ± 0.038	6.906AlaSer: 6.906 ± 0.06	5.191AlaThr: 5.191 ± 0.049	5.469AlaVal: 5.469 ± 0.043	0.917AlaTrp: 0.917 ± 0.019	2.264AlaTyr: 2.264 ± 0.027	0.0AlaXaa: 0.0 ± 0.0
Cys	0.953CysAla: 0.953 ± 0.017	0.252CysCys: 0.252 ± 0.011	0.679CysAsp: 0.679 ± 0.014	0.607CysGlu: 0.607 ± 0.015	0.586CysPhe: 0.586 ± 0.016	0.948CysGly: 0.948 ± 0.02	0.318CysHis: 0.318 ± 0.01	0.783CysIle: 0.783 ± 0.016	0.548CysLys: 0.548 ± 0.013	1.193CysLeu: 1.193 ± 0.019	0.306CysMet: 0.306 ± 0.01	0.45CysAsn: 0.45 ± 0.013	0.615CysPro: 0.615 ± 0.015	0.401CysGln: 0.401 ± 0.012	0.778CysArg: 0.778 ± 0.016	0.979CysSer: 0.979 ± 0.018	0.729CysThr: 0.729 ± 0.017	0.845CysVal: 0.845 ± 0.016	0.176CysTrp: 0.176 ± 0.008	0.381CysTyr: 0.381 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	4.366AspAla: 4.366 ± 0.038	0.638AspCys: 0.638 ± 0.014	4.561AspAsp: 4.561 ± 0.055	4.74AspGlu: 4.74 ± 0.054	2.298AspPhe: 2.298 ± 0.032	3.758AspGly: 3.758 ± 0.04	1.075AspHis: 1.075 ± 0.021	3.794AspIle: 3.794 ± 0.035	2.612AspLys: 2.612 ± 0.028	5.064AspLeu: 5.064 ± 0.047	1.349AspMet: 1.349 ± 0.019	2.145AspAsn: 2.145 ± 0.027	2.764AspPro: 2.764 ± 0.031	1.657AspGln: 1.657 ± 0.022	2.958AspArg: 2.958 ± 0.037	4.321AspSer: 4.321 ± 0.04	2.886AspThr: 2.886 ± 0.031	4.022AspVal: 4.022 ± 0.036	0.721AspTrp: 0.721 ± 0.017	1.809AspTyr: 1.809 ± 0.024	0.0AspXaa: 0.0 ± 0.0
Glu	4.364GluAla: 4.364 ± 0.039	0.663GluCys: 0.663 ± 0.016	4.142GluAsp: 4.142 ± 0.045	5.188GluGlu: 5.188 ± 0.072	2.366GluPhe: 2.366 ± 0.027	3.074GluGly: 3.074 ± 0.037	1.302GluHis: 1.302 ± 0.021	3.725GluIle: 3.725 ± 0.043	3.77GluLys: 3.77 ± 0.056	5.543GluLeu: 5.543 ± 0.049	1.449GluMet: 1.449 ± 0.02	2.58GluAsn: 2.58 ± 0.027	2.3GluPro: 2.3 ± 0.029	2.436GluGln: 2.436 ± 0.028	3.802GluArg: 3.802 ± 0.041	4.695GluSer: 4.695 ± 0.043	3.313GluThr: 3.313 ± 0.038	3.751GluVal: 3.751 ± 0.042	0.808GluTrp: 0.808 ± 0.016	2.119GluTyr: 2.119 ± 0.026	0.0GluXaa: 0.0 ± 0.0
Phe	3.247PheAla: 3.247 ± 0.039	0.615PheCys: 0.615 ± 0.014	2.478PheAsp: 2.478 ± 0.028	2.349PheGlu: 2.349 ± 0.028	1.79PhePhe: 1.79 ± 0.029	2.92PheGly: 2.92 ± 0.043	0.88PheHis: 0.88 ± 0.016	2.171PheIle: 2.171 ± 0.028	1.717PheLys: 1.717 ± 0.02	3.795PheLeu: 3.795 ± 0.037	0.881PheMet: 0.881 ± 0.016	1.551PheAsn: 1.551 ± 0.022	1.899PhePro: 1.899 ± 0.028	1.362PheGln: 1.362 ± 0.021	2.08PheArg: 2.08 ± 0.024	3.332PheSer: 3.332 ± 0.035	2.266PheThr: 2.266 ± 0.028	2.943PheVal: 2.943 ± 0.032	0.633PheTrp: 0.633 ± 0.015	1.316PheTyr: 1.316 ± 0.022	0.0PheXaa: 0.0 ± 0.0
Gly	4.425GlyAla: 4.425 ± 0.047	0.774GlyCys: 0.774 ± 0.015	3.203GlyAsp: 3.203 ± 0.036	3.163GlyGlu: 3.163 ± 0.035	2.677GlyPhe: 2.677 ± 0.033	4.406GlyGly: 4.406 ± 0.057	1.414GlyHis: 1.414 ± 0.027	3.896GlyIle: 3.896 ± 0.039	3.226GlyLys: 3.226 ± 0.033	5.536GlyLeu: 5.536 ± 0.048	1.452GlyMet: 1.452 ± 0.022	2.427GlyAsn: 2.427 ± 0.031	2.557GlyPro: 2.557 ± 0.03	2.143GlyGln: 2.143 ± 0.032	3.499GlyArg: 3.499 ± 0.043	5.139GlySer: 5.139 ± 0.042	3.689GlyThr: 3.689 ± 0.037	4.28GlyVal: 4.28 ± 0.038	0.929GlyTrp: 0.929 ± 0.017	2.186GlyTyr: 2.186 ± 0.033	0.0GlyXaa: 0.0 ± 0.0
His	1.648HisAla: 1.648 ± 0.024	0.312HisCys: 0.312 ± 0.01	1.231HisAsp: 1.231 ± 0.02	1.269HisGlu: 1.269 ± 0.023	0.929HisPhe: 0.929 ± 0.017	1.446HisGly: 1.446 ± 0.02	0.727HisHis: 0.727 ± 0.021	1.327HisIle: 1.327 ± 0.021	0.923HisLys: 0.923 ± 0.017	2.032HisLeu: 2.032 ± 0.03	0.484HisMet: 0.484 ± 0.012	0.818HisAsn: 0.818 ± 0.016	1.343HisPro: 1.343 ± 0.023	0.839HisGln: 0.839 ± 0.016	1.378HisArg: 1.378 ± 0.023	1.778HisSer: 1.778 ± 0.023	1.183HisThr: 1.183 ± 0.021	1.436HisVal: 1.436 ± 0.02	0.28HisTrp: 0.28 ± 0.01	0.736HisTyr: 0.736 ± 0.015	0.0HisXaa: 0.0 ± 0.0
Ile	4.822IleAla: 4.822 ± 0.044	0.855IleCys: 0.855 ± 0.017	3.368IleAsp: 3.368 ± 0.033	3.424IleGlu: 3.424 ± 0.037	2.429IlePhe: 2.429 ± 0.033	3.446IleGly: 3.446 ± 0.037	1.239IleHis: 1.239 ± 0.02	3.147IleIle: 3.147 ± 0.032	2.556IleLys: 2.556 ± 0.029	5.447IleLeu: 5.447 ± 0.047	1.27IleMet: 1.27 ± 0.019	2.08IleAsn: 2.08 ± 0.026	3.174IlePro: 3.174 ± 0.032	2.043IleGln: 2.043 ± 0.028	3.118IleArg: 3.118 ± 0.033	4.874IleSer: 4.874 ± 0.039	3.209IleThr: 3.209 ± 0.03	4.072IleVal: 4.072 ± 0.038	0.733IleTrp: 0.733 ± 0.016	1.81IleTyr: 1.81 ± 0.027	0.0IleXaa: 0.0 ± 0.0
Lys	3.742LysAla: 3.742 ± 0.038	0.589LysCys: 0.589 ± 0.015	2.769LysAsp: 2.769 ± 0.032	3.372LysGlu: 3.372 ± 0.054	1.915LysPhe: 1.915 ± 0.022	2.586LysGly: 2.586 ± 0.028	1.078LysHis: 1.078 ± 0.019	2.78LysIle: 2.78 ± 0.032	3.422LysLys: 3.422 ± 0.052	4.657LysLeu: 4.657 ± 0.042	1.131LysMet: 1.131 ± 0.019	1.923LysAsn: 1.923 ± 0.026	2.255LysPro: 2.255 ± 0.03	1.871LysGln: 1.871 ± 0.025	3.458LysArg: 3.458 ± 0.038	3.967LysSer: 3.967 ± 0.042	2.745LysThr: 2.745 ± 0.033	3.208LysVal: 3.208 ± 0.036	0.689LysTrp: 0.689 ± 0.015	1.883LysTyr: 1.883 ± 0.026	0.0LysXaa: 0.0 ± 0.0
Leu	7.46LeuAla: 7.46 ± 0.054	1.264LeuCys: 1.264 ± 0.021	5.321LeuAsp: 5.321 ± 0.042	5.509LeuGlu: 5.509 ± 0.044	3.671LeuPhe: 3.671 ± 0.038	5.348LeuGly: 5.348 ± 0.049	2.116LeuHis: 2.116 ± 0.026	4.557LeuIle: 4.557 ± 0.04	4.591LeuLys: 4.591 ± 0.04	8.812LeuLeu: 8.812 ± 0.073	1.912LeuMet: 1.912 ± 0.023	3.41LeuAsn: 3.41 ± 0.036	5.101LeuPro: 5.101 ± 0.042	3.864LeuGln: 3.864 ± 0.041	5.781LeuArg: 5.781 ± 0.054	7.982LeuSer: 7.982 ± 0.054	5.03LeuThr: 5.03 ± 0.041	5.85LeuVal: 5.85 ± 0.046	1.112LeuTrp: 1.112 ± 0.019	2.834LeuTyr: 2.834 ± 0.03	0.0LeuXaa: 0.0 ± 0.0
Met	1.989MetAla: 1.989 ± 0.026	0.286MetCys: 0.286 ± 0.01	1.273MetAsp: 1.273 ± 0.02	1.253MetGlu: 1.253 ± 0.021	0.88MetPhe: 0.88 ± 0.019	1.23MetGly: 1.23 ± 0.02	0.493MetHis: 0.493 ± 0.011	1.176MetIle: 1.176 ± 0.018	1.111MetLys: 1.111 ± 0.019	1.963MetLeu: 1.963 ± 0.026	0.598MetMet: 0.598 ± 0.015	0.879MetAsn: 0.879 ± 0.017	1.176MetPro: 1.176 ± 0.021	0.898MetGln: 0.898 ± 0.015	1.299MetArg: 1.299 ± 0.019	2.175MetSer: 2.175 ± 0.026	1.436MetThr: 1.436 ± 0.022	1.392MetVal: 1.392 ± 0.022	0.258MetTrp: 0.258 ± 0.009	0.655MetTyr: 0.655 ± 0.014	0.0MetXaa: 0.0 ± 0.0
Asn	3.094AsnAla: 3.094 ± 0.033	0.517AsnCys: 0.517 ± 0.014	2.225AsnAsp: 2.225 ± 0.027	2.299AsnGlu: 2.299 ± 0.028	1.559AsnPhe: 1.559 ± 0.023	2.891AsnGly: 2.891 ± 0.034	0.759AsnHis: 0.759 ± 0.014	2.45AsnIle: 2.45 ± 0.029	1.755AsnLys: 1.755 ± 0.022	3.445AsnLeu: 3.445 ± 0.029	0.949AsnMet: 0.949 ± 0.017	1.592AsnAsn: 1.592 ± 0.026	2.08AsnPro: 2.08 ± 0.024	1.21AsnGln: 1.21 ± 0.022	1.973AsnArg: 1.973 ± 0.024	3.085AsnSer: 3.085 ± 0.034	2.093AsnThr: 2.093 ± 0.023	2.744AsnVal: 2.744 ± 0.032	0.584AsnTrp: 0.584 ± 0.014	1.228AsnTyr: 1.228 ± 0.022	0.0AsnXaa: 0.0 ± 0.0
Pro	4.153ProAla: 4.153 ± 0.04	0.479ProCys: 0.479 ± 0.014	2.961ProAsp: 2.961 ± 0.029	3.4ProGlu: 3.4 ± 0.032	1.906ProPhe: 1.906 ± 0.025	2.967ProGly: 2.967 ± 0.036	1.094ProHis: 1.094 ± 0.02	2.679ProIle: 2.679 ± 0.026	2.286ProLys: 2.286 ± 0.029	4.42ProLeu: 4.42 ± 0.042	0.972ProMet: 0.972 ± 0.02	1.923ProAsn: 1.923 ± 0.026	3.931ProPro: 3.931 ± 0.07	2.039ProGln: 2.039 ± 0.035	2.728ProArg: 2.728 ± 0.031	5.149ProSer: 5.149 ± 0.053	3.521ProThr: 3.521 ± 0.04	3.508ProVal: 3.508 ± 0.034	0.594ProTrp: 0.594 ± 0.012	1.573ProTyr: 1.573 ± 0.025	0.0ProXaa: 0.0 ± 0.0
Gln	2.798GlnAla: 2.798 ± 0.032	0.411GlnCys: 0.411 ± 0.012	1.821GlnAsp: 1.821 ± 0.023	2.229GlnGlu: 2.229 ± 0.033	1.486GlnPhe: 1.486 ± 0.019	1.909GlnGly: 1.909 ± 0.026	0.98GlnHis: 0.98 ± 0.02	2.083GlnIle: 2.083 ± 0.027	1.951GlnLys: 1.951 ± 0.027	3.598GlnLeu: 3.598 ± 0.036	0.887GlnMet: 0.887 ± 0.017	1.508GlnAsn: 1.508 ± 0.02	2.006GlnPro: 2.006 ± 0.033	2.76GlnGln: 2.76 ± 0.083	2.441GlnArg: 2.441 ± 0.03	3.176GlnSer: 3.176 ± 0.034	2.033GlnThr: 2.033 ± 0.023	2.185GlnVal: 2.185 ± 0.021	0.478GlnTrp: 0.478 ± 0.011	1.334GlnTyr: 1.334 ± 0.024	0.0GlnXaa: 0.0 ± 0.0
Arg	4.206ArgAla: 4.206 ± 0.033	0.668ArgCys: 0.668 ± 0.015	3.155ArgAsp: 3.155 ± 0.042	3.634ArgGlu: 3.634 ± 0.044	2.189ArgPhe: 2.189 ± 0.025	3.173ArgGly: 3.173 ± 0.036	1.507ArgHis: 1.507 ± 0.02	3.258ArgIle: 3.258 ± 0.036	3.562ArgLys: 3.562 ± 0.038	5.344ArgLeu: 5.344 ± 0.045	1.355ArgMet: 1.355 ± 0.02	2.344ArgAsn: 2.344 ± 0.027	2.805ArgPro: 2.805 ± 0.033	2.656ArgGln: 2.656 ± 0.031	4.835ArgArg: 4.835 ± 0.051	4.666ArgSer: 4.666 ± 0.045	3.257ArgThr: 3.257 ± 0.031	3.489ArgVal: 3.489 ± 0.033	0.808ArgTrp: 0.808 ± 0.018	1.879ArgTyr: 1.879 ± 0.026	0.0ArgXaa: 0.0 ± 0.0
Ser	6.894SerAla: 6.894 ± 0.051	0.939SerCys: 0.939 ± 0.02	4.504SerAsp: 4.504 ± 0.041	4.56SerGlu: 4.56 ± 0.042	3.285SerPhe: 3.285 ± 0.032	5.375SerGly: 5.375 ± 0.049	1.855SerHis: 1.855 ± 0.028	4.616SerIle: 4.616 ± 0.038	3.921SerLys: 3.921 ± 0.038	7.612SerLeu: 7.612 ± 0.054	1.827SerMet: 1.827 ± 0.023	3.199SerAsn: 3.199 ± 0.035	5.142SerPro: 5.142 ± 0.062	3.179SerGln: 3.179 ± 0.039	4.949SerArg: 4.949 ± 0.046	9.884SerSer: 9.884 ± 0.093	5.955SerThr: 5.955 ± 0.053	5.383SerVal: 5.383 ± 0.047	1.019SerTrp: 1.019 ± 0.024	2.362SerTyr: 2.362 ± 0.03	0.0SerXaa: 0.0 ± 0.0
Thr	5.031ThrAla: 5.031 ± 0.044	0.722ThrCys: 0.722 ± 0.014	2.953ThrAsp: 2.953 ± 0.032	3.225ThrGlu: 3.225 ± 0.03	2.342ThrPhe: 2.342 ± 0.029	3.825ThrGly: 3.825 ± 0.034	1.134ThrHis: 1.134 ± 0.02	3.574ThrIle: 3.574 ± 0.037	2.735ThrLys: 2.735 ± 0.03	5.187ThrLeu: 5.187 ± 0.044	1.229ThrMet: 1.229 ± 0.02	2.142ThrAsn: 2.142 ± 0.028	3.66ThrPro: 3.66 ± 0.042	1.885ThrGln: 1.885 ± 0.024	3.024ThrArg: 3.024 ± 0.03	5.504ThrSer: 5.504 ± 0.052	4.123ThrThr: 4.123 ± 0.044	4.205ThrVal: 4.205 ± 0.043	0.729ThrTrp: 0.729 ± 0.017	1.773ThrTyr: 1.773 ± 0.024	0.0ThrXaa: 0.0 ± 0.0
Val	5.448ValAla: 5.448 ± 0.047	0.909ValCys: 0.909 ± 0.019	4.028ValAsp: 4.028 ± 0.036	4.025ValGlu: 4.025 ± 0.04	2.756ValPhe: 2.756 ± 0.032	4.001ValGly: 4.001 ± 0.041	1.467ValHis: 1.467 ± 0.021	3.621ValIle: 3.621 ± 0.033	3.177ValLys: 3.177 ± 0.037	6.273ValLeu: 6.273 ± 0.049	1.458ValMet: 1.458 ± 0.026	2.523ValAsn: 2.523 ± 0.025	3.664ValPro: 3.664 ± 0.038	2.419ValGln: 2.419 ± 0.029	3.658ValArg: 3.658 ± 0.032	5.381ValSer: 5.381 ± 0.039	3.804ValThr: 3.804 ± 0.039	4.846ValVal: 4.846 ± 0.043	0.847ValTrp: 0.847 ± 0.018	2.133ValTyr: 2.133 ± 0.023	0.0ValXaa: 0.0 ± 0.0
Trp	0.91TrpAla: 0.91 ± 0.018	0.178TrpCys: 0.178 ± 0.008	0.819TrpAsp: 0.819 ± 0.017	0.675TrpGlu: 0.675 ± 0.014	0.527TrpPhe: 0.527 ± 0.014	0.719TrpGly: 0.719 ± 0.016	0.312TrpHis: 0.312 ± 0.01	0.833TrpIle: 0.833 ± 0.018	0.73TrpLys: 0.73 ± 0.016	1.204TrpLeu: 1.204 ± 0.019	0.34TrpMet: 0.34 ± 0.01	0.652TrpAsn: 0.652 ± 0.013	0.458TrpPro: 0.458 ± 0.013	0.479TrpGln: 0.479 ± 0.014	0.888TrpArg: 0.888 ± 0.019	0.952TrpSer: 0.952 ± 0.017	0.852TrpThr: 0.852 ± 0.017	0.772TrpVal: 0.772 ± 0.016	0.266TrpTrp: 0.266 ± 0.011	0.436TrpTyr: 0.436 ± 0.011	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.341TyrAla: 2.341 ± 0.028	0.496TyrCys: 0.496 ± 0.013	2.01TyrAsp: 2.01 ± 0.025	1.785TyrGlu: 1.785 ± 0.023	1.532TyrPhe: 1.532 ± 0.025	2.144TyrGly: 2.144 ± 0.029	0.79TyrHis: 0.79 ± 0.018	1.888TyrIle: 1.888 ± 0.023	1.406TyrLys: 1.406 ± 0.021	3.117TyrLeu: 3.117 ± 0.032	0.695TyrMet: 0.695 ± 0.012	1.404TyrAsn: 1.404 ± 0.023	1.542TyrPro: 1.542 ± 0.021	1.093TyrGln: 1.093 ± 0.022	1.804TyrArg: 1.804 ± 0.024	2.516TyrSer: 2.516 ± 0.031	1.687TyrThr: 1.687 ± 0.024	2.039TyrVal: 2.039 ± 0.026	0.42TyrTrp: 0.42 ± 0.012	1.271TyrTyr: 1.271 ± 0.021	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 8136 proteins (3319957 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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