Amino acid dipepetide frequency for Cryphonectria hypovirus 2-NB58

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.097AlaAla: 5.097 ± 0.264
1.073AlaCys: 1.073 ± 0.54
5.097AlaAsp: 5.097 ± 1.414
5.097AlaGlu: 5.097 ± 0.264
2.414AlaPhe: 2.414 ± 0.065
6.974AlaGly: 6.974 ± 1.091
1.341AlaHis: 1.341 ± 0.675
3.219AlaIle: 3.219 ± 0.68
3.219AlaLys: 3.219 ± 0.469
5.097AlaLeu: 5.097 ± 2.035
2.951AlaMet: 2.951 ± 0.334
3.487AlaAsn: 3.487 ± 2.845
2.146AlaPro: 2.146 ± 0.07
2.414AlaGln: 2.414 ± 1.214
5.901AlaArg: 5.901 ± 1.631
2.951AlaSer: 2.951 ± 0.815
3.487AlaThr: 3.487 ± 0.604
4.828AlaVal: 4.828 ± 4.47
2.414AlaTrp: 2.414 ± 0.065
1.878AlaTyr: 1.878 ± 0.945
0.0AlaXaa: 0.0 ± 0.0
Cys
0.268CysAla: 0.268 ± 0.135
0.536CysCys: 0.536 ± 0.88
0.536CysAsp: 0.536 ± 0.27
1.609CysGlu: 1.609 ± 0.81
0.268CysPhe: 0.268 ± 0.135
0.805CysGly: 0.805 ± 0.745
0.268CysHis: 0.268 ± 0.135
0.268CysIle: 0.268 ± 1.015
1.341CysLys: 1.341 ± 0.475
1.073CysLeu: 1.073 ± 0.61
0.536CysMet: 0.536 ± 0.27
0.268CysAsn: 0.268 ± 0.135
0.805CysPro: 0.805 ± 0.745
0.0CysGln: 0.0 ± 0.0
1.073CysArg: 1.073 ± 0.54
1.609CysSer: 1.609 ± 3.79
0.805CysThr: 0.805 ± 0.405
0.805CysVal: 0.805 ± 0.405
0.268CysTrp: 0.268 ± 0.135
0.805CysTyr: 0.805 ± 0.405
0.0CysXaa: 0.0 ± 0.0
Asp
4.292AspAla: 4.292 ± 1.29
0.268AspCys: 0.268 ± 1.015
3.487AspAsp: 3.487 ± 0.545
6.17AspGlu: 6.17 ± 1.954
3.755AspPhe: 3.755 ± 1.889
3.487AspGly: 3.487 ± 0.604
1.609AspHis: 1.609 ± 0.81
2.951AspIle: 2.951 ± 0.334
3.487AspLys: 3.487 ± 0.604
3.219AspLeu: 3.219 ± 1.619
1.609AspMet: 1.609 ± 0.34
2.951AspAsn: 2.951 ± 1.484
2.146AspPro: 2.146 ± 1.08
1.341AspGln: 1.341 ± 0.475
2.682AspArg: 2.682 ± 1.349
4.024AspSer: 4.024 ± 0.874
1.341AspThr: 1.341 ± 0.675
3.755AspVal: 3.755 ± 1.56
1.341AspTrp: 1.341 ± 0.675
1.878AspTyr: 1.878 ± 0.205
0.0AspXaa: 0.0 ± 0.0
Glu
3.755GluAla: 3.755 ± 0.739
0.805GluCys: 0.805 ± 0.745
4.56GluAsp: 4.56 ± 1.156
5.365GluGlu: 5.365 ± 1.549
2.146GluPhe: 2.146 ± 2.37
4.292GluGly: 4.292 ± 1.29
1.341GluHis: 1.341 ± 0.475
3.219GluIle: 3.219 ± 1.619
2.951GluLys: 2.951 ± 0.815
7.242GluLeu: 7.242 ± 0.194
1.878GluMet: 1.878 ± 0.205
3.487GluAsn: 3.487 ± 0.604
4.292GluPro: 4.292 ± 1.29
2.682GluGln: 2.682 ± 0.2
3.219GluArg: 3.219 ± 0.469
2.682GluSer: 2.682 ± 0.95
3.755GluThr: 3.755 ± 1.56
4.56GluVal: 4.56 ± 2.294
0.268GluTrp: 0.268 ± 0.135
2.682GluTyr: 2.682 ± 1.349
0.0GluXaa: 0.0 ± 0.0
Phe
3.487PheAla: 3.487 ± 1.754
0.536PheCys: 0.536 ± 0.88
1.878PheAsp: 1.878 ± 1.355
1.341PheGlu: 1.341 ± 1.625
2.146PhePhe: 2.146 ± 0.07
3.487PheGly: 3.487 ± 1.754
1.609PheHis: 1.609 ± 0.81
2.414PheIle: 2.414 ± 1.214
4.828PheLys: 4.828 ± 3.32
6.17PheLeu: 6.17 ± 3.104
2.146PheMet: 2.146 ± 1.08
1.341PheAsn: 1.341 ± 0.475
1.878PhePro: 1.878 ± 0.205
0.536PheGln: 0.536 ± 0.27
1.609PheArg: 1.609 ± 0.34
1.341PheSer: 1.341 ± 0.675
2.146PheThr: 2.146 ± 0.07
2.146PheVal: 2.146 ± 1.08
1.609PheTrp: 1.609 ± 0.81
0.805PheTyr: 0.805 ± 0.405
0.0PheXaa: 0.0 ± 0.0
Gly
3.219GlyAla: 3.219 ± 0.469
1.341GlyCys: 1.341 ± 0.675
2.682GlyAsp: 2.682 ± 1.349
1.609GlyGlu: 1.609 ± 0.34
2.951GlyPhe: 2.951 ± 0.815
4.024GlyGly: 4.024 ± 0.276
1.878GlyHis: 1.878 ± 0.205
5.901GlyIle: 5.901 ± 0.481
4.292GlyLys: 4.292 ± 1.29
5.633GlyLeu: 5.633 ± 0.534
2.951GlyMet: 2.951 ± 0.334
1.341GlyAsn: 1.341 ± 0.475
1.341GlyPro: 1.341 ± 0.675
1.341GlyGln: 1.341 ± 0.475
5.097GlyArg: 5.097 ± 0.886
1.609GlySer: 1.609 ± 0.81
3.755GlyThr: 3.755 ± 0.411
5.097GlyVal: 5.097 ± 2.564
1.609GlyTrp: 1.609 ± 0.34
1.609GlyTyr: 1.609 ± 0.34
0.0GlyXaa: 0.0 ± 0.0
His
0.805HisAla: 0.805 ± 0.745
0.536HisCys: 0.536 ± 0.88
1.609HisAsp: 1.609 ± 0.34
1.073HisGlu: 1.073 ± 0.54
1.073HisPhe: 1.073 ± 0.54
1.073HisGly: 1.073 ± 0.61
0.536HisHis: 0.536 ± 0.27
0.536HisIle: 0.536 ± 0.27
1.609HisLys: 1.609 ± 1.49
3.219HisLeu: 3.219 ± 0.68
0.268HisMet: 0.268 ± 1.015
2.146HisAsn: 2.146 ± 0.07
1.878HisPro: 1.878 ± 0.205
1.073HisGln: 1.073 ± 0.54
1.073HisArg: 1.073 ± 0.54
1.073HisSer: 1.073 ± 0.61
1.073HisThr: 1.073 ± 0.54
2.414HisVal: 2.414 ± 1.214
1.073HisTrp: 1.073 ± 0.54
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.487IleAla: 3.487 ± 1.695
1.341IleCys: 1.341 ± 0.475
3.219IleAsp: 3.219 ± 1.619
1.878IleGlu: 1.878 ± 0.205
2.414IlePhe: 2.414 ± 1.214
2.951IleGly: 2.951 ± 0.334
1.609IleHis: 1.609 ± 0.81
1.341IleIle: 1.341 ± 0.675
4.024IleLys: 4.024 ± 1.425
3.219IleLeu: 3.219 ± 0.68
1.609IleMet: 1.609 ± 0.81
1.609IleAsn: 1.609 ± 0.34
4.56IlePro: 4.56 ± 2.294
1.341IleGln: 1.341 ± 0.475
3.487IleArg: 3.487 ± 1.695
4.024IleSer: 4.024 ± 0.276
3.487IleThr: 3.487 ± 1.754
1.878IleVal: 1.878 ± 0.945
1.073IleTrp: 1.073 ± 0.61
1.609IleTyr: 1.609 ± 0.81
0.0IleXaa: 0.0 ± 0.0
Lys
5.365LysAla: 5.365 ± 0.399
1.341LysCys: 1.341 ± 0.475
3.487LysAsp: 3.487 ± 0.545
4.292LysGlu: 4.292 ± 1.29
2.414LysPhe: 2.414 ± 1.214
2.682LysGly: 2.682 ± 0.2
1.073LysHis: 1.073 ± 0.54
2.414LysIle: 2.414 ± 0.065
3.219LysLys: 3.219 ± 1.83
4.828LysLeu: 4.828 ± 1.279
0.805LysMet: 0.805 ± 0.673
2.682LysAsn: 2.682 ± 0.95
3.219LysPro: 3.219 ± 4.13
2.414LysGln: 2.414 ± 1.085
5.365LysArg: 5.365 ± 1.901
4.56LysSer: 4.56 ± 1.156
3.487LysThr: 3.487 ± 2.845
5.633LysVal: 5.633 ± 0.534
1.341LysTrp: 1.341 ± 0.675
2.146LysTyr: 2.146 ± 1.08
0.0LysXaa: 0.0 ± 0.0
Leu
6.17LeuAla: 6.17 ± 0.346
0.536LeuCys: 0.536 ± 0.27
4.292LeuAsp: 4.292 ± 1.009
8.315LeuGlu: 8.315 ± 0.416
2.682LeuPhe: 2.682 ± 1.349
2.146LeuGly: 2.146 ± 0.07
2.146LeuHis: 2.146 ± 0.07
3.755LeuIle: 3.755 ± 0.739
5.365LeuLys: 5.365 ± 0.399
7.779LeuLeu: 7.779 ± 1.614
1.341LeuMet: 1.341 ± 0.675
3.487LeuAsn: 3.487 ± 1.695
6.438LeuPro: 6.438 ± 2.089
2.146LeuGln: 2.146 ± 1.08
10.193LeuArg: 10.193 ± 4.071
4.292LeuSer: 4.292 ± 2.159
4.828LeuThr: 4.828 ± 1.279
5.633LeuVal: 5.633 ± 2.834
1.609LeuTrp: 1.609 ± 0.34
2.951LeuTyr: 2.951 ± 1.484
0.0LeuXaa: 0.0 ± 0.0
Met
2.146MetAla: 2.146 ± 1.22
0.536MetCys: 0.536 ± 0.27
1.073MetAsp: 1.073 ± 0.54
1.341MetGlu: 1.341 ± 0.675
0.805MetPhe: 0.805 ± 1.895
0.805MetGly: 0.805 ± 0.405
0.536MetHis: 0.536 ± 0.27
1.341MetIle: 1.341 ± 0.675
1.073MetLys: 1.073 ± 0.54
3.487MetLeu: 3.487 ± 1.754
1.609MetMet: 1.609 ± 0.81
0.268MetAsn: 0.268 ± 0.135
3.487MetPro: 3.487 ± 0.545
0.268MetGln: 0.268 ± 0.135
0.805MetArg: 0.805 ± 0.405
1.341MetSer: 1.341 ± 0.475
2.146MetThr: 2.146 ± 0.07
2.146MetVal: 2.146 ± 1.08
1.341MetTrp: 1.341 ± 0.475
1.341MetTyr: 1.341 ± 0.675
0.0MetXaa: 0.0 ± 0.0
Asn
1.878AsnAla: 1.878 ± 2.505
0.268AsnCys: 0.268 ± 0.135
1.609AsnAsp: 1.609 ± 0.81
2.951AsnGlu: 2.951 ± 0.815
1.341AsnPhe: 1.341 ± 0.675
1.878AsnGly: 1.878 ± 0.205
1.073AsnHis: 1.073 ± 0.54
2.414AsnIle: 2.414 ± 0.065
1.341AsnLys: 1.341 ± 0.475
4.56AsnLeu: 4.56 ± 1.144
0.805AsnMet: 0.805 ± 0.261
0.805AsnAsn: 0.805 ± 0.405
4.292AsnPro: 4.292 ± 1.29
1.341AsnGln: 1.341 ± 0.675
4.56AsnArg: 4.56 ± 2.305
1.073AsnSer: 1.073 ± 0.54
1.878AsnThr: 1.878 ± 0.945
1.341AsnVal: 1.341 ± 1.625
1.878AsnTrp: 1.878 ± 0.205
1.609AsnTyr: 1.609 ± 0.81
0.0AsnXaa: 0.0 ± 0.0
Pro
4.292ProAla: 4.292 ± 2.44
1.609ProCys: 1.609 ± 1.49
3.487ProAsp: 3.487 ± 0.604
4.56ProGlu: 4.56 ± 1.144
2.951ProPhe: 2.951 ± 0.334
5.097ProGly: 5.097 ± 2.035
1.073ProHis: 1.073 ± 0.54
1.609ProIle: 1.609 ± 0.81
4.024ProLys: 4.024 ± 0.276
3.487ProLeu: 3.487 ± 1.754
1.609ProMet: 1.609 ± 0.81
1.878ProAsn: 1.878 ± 0.945
5.097ProPro: 5.097 ± 1.414
1.609ProGln: 1.609 ± 0.34
5.365ProArg: 5.365 ± 0.751
4.56ProSer: 4.56 ± 1.156
4.292ProThr: 4.292 ± 1.009
2.951ProVal: 2.951 ± 1.484
0.805ProTrp: 0.805 ± 0.405
2.146ProTyr: 2.146 ± 1.08
0.0ProXaa: 0.0 ± 0.0
Gln
3.755GlnAla: 3.755 ± 0.739
0.536GlnCys: 0.536 ± 0.27
2.414GlnAsp: 2.414 ± 0.065
1.341GlnGlu: 1.341 ± 1.625
1.878GlnPhe: 1.878 ± 0.945
1.341GlnGly: 1.341 ± 0.675
0.268GlnHis: 0.268 ± 0.135
1.878GlnIle: 1.878 ± 0.945
2.951GlnLys: 2.951 ± 0.334
2.146GlnLeu: 2.146 ± 1.22
0.268GlnMet: 0.268 ± 0.135
0.805GlnAsn: 0.805 ± 0.405
2.682GlnPro: 2.682 ± 0.2
0.536GlnGln: 0.536 ± 0.27
2.414GlnArg: 2.414 ± 1.085
1.341GlnSer: 1.341 ± 2.775
2.951GlnThr: 2.951 ± 0.334
1.073GlnVal: 1.073 ± 0.54
1.609GlnTrp: 1.609 ± 0.34
1.073GlnTyr: 1.073 ± 0.54
0.0GlnXaa: 0.0 ± 0.0
Arg
3.755ArgAla: 3.755 ± 1.56
0.0ArgCys: 0.0 ± 0.0
4.024ArgAsp: 4.024 ± 2.024
4.56ArgGlu: 4.56 ± 2.305
4.828ArgPhe: 4.828 ± 1.279
3.487ArgGly: 3.487 ± 0.604
1.609ArgHis: 1.609 ± 2.64
4.292ArgIle: 4.292 ± 1.009
4.292ArgLys: 4.292 ± 0.141
6.438ArgLeu: 6.438 ± 1.361
1.609ArgMet: 1.609 ± 0.34
2.682ArgAsn: 2.682 ± 2.1
3.487ArgPro: 3.487 ± 0.604
3.219ArgGln: 3.219 ± 2.98
3.487ArgArg: 3.487 ± 1.695
6.706ArgSer: 6.706 ± 5.825
3.487ArgThr: 3.487 ± 1.695
2.951ArgVal: 2.951 ± 0.334
1.341ArgTrp: 1.341 ± 0.675
4.024ArgTyr: 4.024 ± 0.276
0.0ArgXaa: 0.0 ± 0.0
Ser
5.097SerAla: 5.097 ± 0.264
0.268SerCys: 0.268 ± 1.015
2.146SerAsp: 2.146 ± 0.07
3.487SerGlu: 3.487 ± 2.845
3.219SerPhe: 3.219 ± 0.68
5.097SerGly: 5.097 ± 0.264
1.341SerHis: 1.341 ± 2.775
4.292SerIle: 4.292 ± 3.59
4.024SerLys: 4.024 ± 1.425
4.024SerLeu: 4.024 ± 0.874
1.073SerMet: 1.073 ± 0.54
1.341SerAsn: 1.341 ± 0.675
2.146SerPro: 2.146 ± 0.07
4.024SerGln: 4.024 ± 0.276
4.292SerArg: 4.292 ± 2.44
4.828SerSer: 4.828 ± 1.021
1.609SerThr: 1.609 ± 0.34
2.951SerVal: 2.951 ± 1.484
1.878SerTrp: 1.878 ± 1.355
1.609SerTyr: 1.609 ± 0.81
0.0SerXaa: 0.0 ± 0.0
Thr
4.828ThrAla: 4.828 ± 0.129
0.268ThrCys: 0.268 ± 0.135
2.414ThrAsp: 2.414 ± 0.065
1.878ThrGlu: 1.878 ± 0.205
1.341ThrPhe: 1.341 ± 0.675
2.951ThrGly: 2.951 ± 0.334
1.073ThrHis: 1.073 ± 0.54
2.682ThrIle: 2.682 ± 1.349
3.487ThrLys: 3.487 ± 0.545
4.292ThrLeu: 4.292 ± 1.29
1.341ThrMet: 1.341 ± 0.675
3.487ThrAsn: 3.487 ± 0.604
3.755ThrPro: 3.755 ± 0.739
1.341ThrGln: 1.341 ± 1.625
3.755ThrArg: 3.755 ± 1.56
2.682ThrSer: 2.682 ± 0.2
1.878ThrThr: 1.878 ± 0.945
5.097ThrVal: 5.097 ± 0.264
1.609ThrTrp: 1.609 ± 0.81
1.609ThrTyr: 1.609 ± 0.81
0.0ThrXaa: 0.0 ± 0.0
Val
4.56ValAla: 4.56 ± 1.156
1.073ValCys: 1.073 ± 0.54
3.219ValAsp: 3.219 ± 0.469
4.828ValGlu: 4.828 ± 2.429
2.682ValPhe: 2.682 ± 0.2
2.951ValGly: 2.951 ± 0.334
1.878ValHis: 1.878 ± 0.205
3.219ValIle: 3.219 ± 0.469
2.682ValLys: 2.682 ± 0.2
5.901ValLeu: 5.901 ± 1.819
1.341ValMet: 1.341 ± 0.475
2.146ValAsn: 2.146 ± 1.08
4.56ValPro: 4.56 ± 2.294
1.609ValGln: 1.609 ± 0.81
1.878ValArg: 1.878 ± 1.355
4.828ValSer: 4.828 ± 0.129
4.292ValThr: 4.292 ± 1.009
3.487ValVal: 3.487 ± 1.695
1.878ValTrp: 1.878 ± 0.945
3.219ValTyr: 3.219 ± 0.469
0.0ValXaa: 0.0 ± 0.0
Trp
2.414TrpAla: 2.414 ± 1.214
0.536TrpCys: 0.536 ± 0.27
1.609TrpAsp: 1.609 ± 0.81
1.341TrpGlu: 1.341 ± 0.675
0.536TrpPhe: 0.536 ± 0.88
1.073TrpGly: 1.073 ± 0.54
0.805TrpHis: 0.805 ± 0.745
1.609TrpIle: 1.609 ± 1.49
1.878TrpLys: 1.878 ± 1.355
2.146TrpLeu: 2.146 ± 1.08
0.805TrpMet: 0.805 ± 0.405
0.805TrpAsn: 0.805 ± 0.745
1.341TrpPro: 1.341 ± 0.475
1.609TrpGln: 1.609 ± 0.81
1.878TrpArg: 1.878 ± 0.945
2.146TrpSer: 2.146 ± 0.07
0.0TrpThr: 0.0 ± 0.0
1.609TrpVal: 1.609 ± 0.81
1.341TrpTrp: 1.341 ± 0.675
1.341TrpTyr: 1.341 ± 0.475
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.414TyrAla: 2.414 ± 0.065
0.536TyrCys: 0.536 ± 0.27
2.951TyrAsp: 2.951 ± 1.484
2.146TyrGlu: 2.146 ± 0.07
1.609TyrPhe: 1.609 ± 0.81
2.682TyrGly: 2.682 ± 1.349
1.073TyrHis: 1.073 ± 0.61
0.805TyrIle: 0.805 ± 0.405
2.951TyrLys: 2.951 ± 1.484
2.146TyrLeu: 2.146 ± 1.08
1.073TyrMet: 1.073 ± 0.54
1.878TyrAsn: 1.878 ± 0.205
2.951TyrPro: 2.951 ± 1.484
2.414TyrGln: 2.414 ± 1.214
2.146TyrArg: 2.146 ± 1.08
1.073TyrSer: 1.073 ± 0.54
1.073TyrThr: 1.073 ± 0.54
1.878TyrVal: 1.878 ± 0.205
0.536TyrTrp: 0.536 ± 0.88
1.341TyrTyr: 1.341 ± 0.475
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (3729 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski