Amino acid dipepetide frequency for Beihai picorna-like virus 84

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.531AlaAla: 7.531 ± 2.004
1.585AlaCys: 1.585 ± 0.834
4.36AlaAsp: 4.36 ± 2.272
7.134AlaGlu: 7.134 ± 1.796
2.774AlaPhe: 2.774 ± 0.155
2.774AlaGly: 2.774 ± 0.807
0.793AlaHis: 0.793 ± 0.417
2.774AlaIle: 2.774 ± 0.155
4.756AlaLys: 4.756 ± 1.411
8.323AlaLeu: 8.323 ± 0.839
3.567AlaMet: 3.567 ± 0.799
2.378AlaAsn: 2.378 ± 1.251
4.756AlaPro: 4.756 ± 1.411
3.567AlaGln: 3.567 ± 0.08
8.72AlaArg: 8.72 ± 1.325
5.945AlaSer: 5.945 ± 0.518
7.134AlaThr: 7.134 ± 0.492
8.323AlaVal: 8.323 ± 1.117
0.0AlaTrp: 0.0 ± 0.0
1.982AlaTyr: 1.982 ± 0.262
0.0AlaXaa: 0.0 ± 0.0
Cys
1.982CysAla: 1.982 ± 0.262
0.0CysCys: 0.0 ± 0.0
1.982CysAsp: 1.982 ± 0.262
3.171CysGlu: 3.171 ± 1.668
1.585CysPhe: 1.585 ± 0.834
1.982CysGly: 1.982 ± 0.39
0.396CysHis: 0.396 ± 0.208
0.793CysIle: 0.793 ± 0.417
1.585CysLys: 1.585 ± 0.834
1.982CysLeu: 1.982 ± 0.262
1.189CysMet: 1.189 ± 0.027
0.0CysAsn: 0.0 ± 0.0
0.396CysPro: 0.396 ± 0.444
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
1.585CysSer: 1.585 ± 0.834
1.585CysThr: 1.585 ± 0.834
0.793CysVal: 0.793 ± 0.887
0.0CysTrp: 0.0 ± 0.0
0.396CysTyr: 0.396 ± 0.208
0.0CysXaa: 0.0 ± 0.0
Asp
5.153AspAla: 5.153 ± 0.101
0.793AspCys: 0.793 ± 0.235
4.756AspAsp: 4.756 ± 0.107
5.945AspGlu: 5.945 ± 1.17
1.982AspPhe: 1.982 ± 0.262
6.342AspGly: 6.342 ± 0.727
1.982AspHis: 1.982 ± 0.39
3.964AspIle: 3.964 ± 1.828
2.774AspLys: 2.774 ± 0.807
6.342AspLeu: 6.342 ± 0.727
1.585AspMet: 1.585 ± 0.182
2.774AspAsn: 2.774 ± 0.155
2.774AspPro: 2.774 ± 1.149
0.793AspGln: 0.793 ± 0.235
1.982AspArg: 1.982 ± 1.042
1.189AspSer: 1.189 ± 0.625
3.171AspThr: 3.171 ± 2.897
6.342AspVal: 6.342 ± 1.229
0.0AspTrp: 0.0 ± 0.0
2.378AspTyr: 2.378 ± 0.054
0.0AspXaa: 0.0 ± 0.0
Glu
7.134GluAla: 7.134 ± 3.1
2.378GluCys: 2.378 ± 1.251
4.36GluAsp: 4.36 ± 0.337
3.964GluGlu: 3.964 ± 1.432
2.774GluPhe: 2.774 ± 1.459
3.964GluGly: 3.964 ± 0.128
0.793GluHis: 0.793 ± 0.417
3.171GluIle: 3.171 ± 0.941
4.36GluLys: 4.36 ± 2.293
5.153GluLeu: 5.153 ± 3.159
2.378GluMet: 2.378 ± 0.599
2.378GluAsn: 2.378 ± 0.054
0.793GluPro: 0.793 ± 0.887
1.982GluGln: 1.982 ± 0.39
6.738GluArg: 6.738 ± 0.283
4.36GluSer: 4.36 ± 1.641
3.964GluThr: 3.964 ± 0.524
3.567GluVal: 3.567 ± 0.08
1.982GluTrp: 1.982 ± 1.042
4.36GluTyr: 4.36 ± 1.641
0.0GluXaa: 0.0 ± 0.0
Phe
2.774PheAla: 2.774 ± 0.155
0.396PheCys: 0.396 ± 0.208
3.964PheAsp: 3.964 ± 0.78
2.774PheGlu: 2.774 ± 0.497
1.189PhePhe: 1.189 ± 0.679
3.171PheGly: 3.171 ± 1.015
0.396PheHis: 0.396 ± 0.444
0.396PheIle: 0.396 ± 0.208
0.793PheLys: 0.793 ± 0.235
3.964PheLeu: 3.964 ± 0.128
0.0PheMet: 0.0 ± 0.0
1.982PheAsn: 1.982 ± 0.39
2.378PhePro: 2.378 ± 0.706
1.585PheGln: 1.585 ± 1.122
2.378PheArg: 2.378 ± 0.599
1.982PheSer: 1.982 ± 1.566
1.189PheThr: 1.189 ± 0.625
5.153PheVal: 5.153 ± 0.551
0.396PheTrp: 0.396 ± 0.208
1.982PheTyr: 1.982 ± 0.914
0.0PheXaa: 0.0 ± 0.0
Gly
3.171GlyAla: 3.171 ± 1.015
1.585GlyCys: 1.585 ± 0.834
6.342GlyAsp: 6.342 ± 0.727
7.531GlyGlu: 7.531 ± 0.604
3.171GlyPhe: 3.171 ± 0.941
3.171GlyGly: 3.171 ± 2.245
0.793GlyHis: 0.793 ± 0.417
3.964GlyIle: 3.964 ± 0.78
3.567GlyLys: 3.567 ± 0.732
4.36GlyLeu: 4.36 ± 1.641
1.189GlyMet: 1.189 ± 0.027
1.189GlyAsn: 1.189 ± 0.625
5.153GlyPro: 5.153 ± 1.855
2.774GlyGln: 2.774 ± 0.807
3.171GlyArg: 3.171 ± 0.363
5.549GlySer: 5.549 ± 2.298
3.964GlyThr: 3.964 ± 0.78
5.153GlyVal: 5.153 ± 1.855
0.793GlyTrp: 0.793 ± 0.887
2.378GlyTyr: 2.378 ± 0.706
0.0GlyXaa: 0.0 ± 0.0
His
1.585HisAla: 1.585 ± 0.182
1.189HisCys: 1.189 ± 0.625
0.0HisAsp: 0.0 ± 0.0
0.396HisGlu: 0.396 ± 0.208
0.396HisPhe: 0.396 ± 0.208
1.189HisGly: 1.189 ± 0.027
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
0.793HisLys: 0.793 ± 0.887
1.585HisLeu: 1.585 ± 0.182
0.396HisMet: 0.396 ± 0.208
0.0HisAsn: 0.0 ± 0.0
1.189HisPro: 1.189 ± 0.027
0.396HisGln: 0.396 ± 0.444
0.793HisArg: 0.793 ± 0.417
1.189HisSer: 1.189 ± 0.679
0.0HisThr: 0.0 ± 0.0
1.982HisVal: 1.982 ± 1.042
0.396HisTrp: 0.396 ± 0.208
0.793HisTyr: 0.793 ± 0.417
0.0HisXaa: 0.0 ± 0.0
Ile
3.171IleAla: 3.171 ± 2.897
0.396IleCys: 0.396 ± 0.208
2.774IleAsp: 2.774 ± 0.807
2.774IleGlu: 2.774 ± 0.155
0.793IlePhe: 0.793 ± 0.235
3.171IleGly: 3.171 ± 0.289
1.982IleHis: 1.982 ± 0.914
2.378IleIle: 2.378 ± 0.054
1.585IleLys: 1.585 ± 0.47
2.378IleLeu: 2.378 ± 0.599
0.793IleMet: 0.793 ± 0.189
2.378IleAsn: 2.378 ± 0.599
4.36IlePro: 4.36 ± 2.272
1.189IleGln: 1.189 ± 0.027
2.378IleArg: 2.378 ± 1.251
3.567IleSer: 3.567 ± 0.732
2.378IleThr: 2.378 ± 1.251
2.378IleVal: 2.378 ± 0.054
0.396IleTrp: 0.396 ± 0.208
0.793IleTyr: 0.793 ± 0.235
0.0IleXaa: 0.0 ± 0.0
Lys
6.738LysAla: 6.738 ± 1.587
0.396LysCys: 0.396 ± 0.208
2.378LysAsp: 2.378 ± 0.599
1.585LysGlu: 1.585 ± 0.834
2.378LysPhe: 2.378 ± 0.706
2.378LysGly: 2.378 ± 1.251
0.793LysHis: 0.793 ± 0.417
2.378LysIle: 2.378 ± 0.706
3.171LysLys: 3.171 ± 1.668
6.342LysLeu: 6.342 ± 0.727
0.793LysMet: 0.793 ± 0.235
1.585LysAsn: 1.585 ± 0.47
1.982LysPro: 1.982 ± 0.914
2.774LysGln: 2.774 ± 0.155
1.982LysArg: 1.982 ± 0.262
3.171LysSer: 3.171 ± 0.289
5.549LysThr: 5.549 ± 1.614
5.549LysVal: 5.549 ± 0.962
0.793LysTrp: 0.793 ± 0.417
2.378LysTyr: 2.378 ± 0.599
0.0LysXaa: 0.0 ± 0.0
Leu
6.342LeuAla: 6.342 ± 1.379
0.396LeuCys: 0.396 ± 0.208
6.342LeuAsp: 6.342 ± 1.229
5.153LeuGlu: 5.153 ± 0.754
2.378LeuPhe: 2.378 ± 0.706
5.945LeuGly: 5.945 ± 2.09
1.585LeuHis: 1.585 ± 0.182
1.982LeuIle: 1.982 ± 0.262
5.549LeuLys: 5.549 ± 0.962
3.964LeuLeu: 3.964 ± 2.48
3.171LeuMet: 3.171 ± 0.363
4.36LeuAsn: 4.36 ± 0.968
2.378LeuPro: 2.378 ± 1.358
3.567LeuGln: 3.567 ± 0.572
4.756LeuArg: 4.756 ± 1.411
6.738LeuSer: 6.738 ± 0.369
6.342LeuThr: 6.342 ± 0.075
5.549LeuVal: 5.549 ± 0.962
0.793LeuTrp: 0.793 ± 0.235
2.378LeuTyr: 2.378 ± 0.706
0.0LeuXaa: 0.0 ± 0.0
Met
2.774MetAla: 2.774 ± 1.149
1.982MetCys: 1.982 ± 1.042
1.982MetAsp: 1.982 ± 0.39
2.774MetGlu: 2.774 ± 0.807
0.793MetPhe: 0.793 ± 0.417
1.189MetGly: 1.189 ± 0.625
0.793MetHis: 0.793 ± 0.417
1.982MetIle: 1.982 ± 0.914
1.982MetLys: 1.982 ± 1.042
1.982MetLeu: 1.982 ± 0.39
1.585MetMet: 1.585 ± 0.834
0.793MetAsn: 0.793 ± 0.417
0.793MetPro: 0.793 ± 0.417
0.793MetGln: 0.793 ± 0.887
1.982MetArg: 1.982 ± 0.39
1.585MetSer: 1.585 ± 0.182
2.774MetThr: 2.774 ± 0.155
0.396MetVal: 0.396 ± 0.444
0.0MetTrp: 0.0 ± 0.0
1.189MetTyr: 1.189 ± 1.331
0.0MetXaa: 0.0 ± 0.0
Asn
4.756AsnAla: 4.756 ± 0.545
1.189AsnCys: 1.189 ± 0.027
2.378AsnAsp: 2.378 ± 0.054
3.964AsnGlu: 3.964 ± 1.176
1.189AsnPhe: 1.189 ± 0.027
1.982AsnGly: 1.982 ± 0.39
0.396AsnHis: 0.396 ± 0.444
0.396AsnIle: 0.396 ± 0.208
1.982AsnLys: 1.982 ± 0.39
3.171AsnLeu: 3.171 ± 0.289
0.396AsnMet: 0.396 ± 0.444
0.793AsnAsn: 0.793 ± 0.235
3.964AsnPro: 3.964 ± 0.78
0.396AsnGln: 0.396 ± 0.208
1.585AsnArg: 1.585 ± 0.182
1.189AsnSer: 1.189 ± 0.027
1.982AsnThr: 1.982 ± 0.262
3.171AsnVal: 3.171 ± 0.363
0.396AsnTrp: 0.396 ± 0.208
0.396AsnTyr: 0.396 ± 0.444
0.0AsnXaa: 0.0 ± 0.0
Pro
4.36ProAla: 4.36 ± 2.272
0.793ProCys: 0.793 ± 0.235
1.189ProAsp: 1.189 ± 1.331
2.774ProGlu: 2.774 ± 0.155
1.585ProPhe: 1.585 ± 0.47
3.964ProGly: 3.964 ± 0.524
1.189ProHis: 1.189 ± 0.027
2.774ProIle: 2.774 ± 1.149
0.0ProLys: 0.0 ± 0.0
1.982ProLeu: 1.982 ± 0.914
3.567ProMet: 3.567 ± 0.732
2.378ProAsn: 2.378 ± 0.706
1.189ProPro: 1.189 ± 1.331
1.982ProGln: 1.982 ± 0.262
0.793ProArg: 0.793 ± 0.417
2.378ProSer: 2.378 ± 0.706
2.378ProThr: 2.378 ± 2.01
3.964ProVal: 3.964 ± 1.176
1.189ProTrp: 1.189 ± 0.027
2.774ProTyr: 2.774 ± 0.497
0.0ProXaa: 0.0 ± 0.0
Gln
3.964GlnAla: 3.964 ± 0.78
0.0GlnCys: 0.0 ± 0.0
0.793GlnAsp: 0.793 ± 0.887
2.774GlnGlu: 2.774 ± 0.807
1.585GlnPhe: 1.585 ± 0.182
1.982GlnGly: 1.982 ± 1.566
0.0GlnHis: 0.0 ± 0.0
1.189GlnIle: 1.189 ± 0.625
2.774GlnLys: 2.774 ± 0.155
3.171GlnLeu: 3.171 ± 0.289
1.982GlnMet: 1.982 ± 0.39
0.793GlnAsn: 0.793 ± 0.235
1.585GlnPro: 1.585 ± 1.122
1.982GlnGln: 1.982 ± 0.914
1.982GlnArg: 1.982 ± 0.914
1.585GlnSer: 1.585 ± 0.47
1.982GlnThr: 1.982 ± 1.042
1.982GlnVal: 1.982 ± 0.39
0.0GlnTrp: 0.0 ± 0.0
0.396GlnTyr: 0.396 ± 0.444
0.0GlnXaa: 0.0 ± 0.0
Arg
3.171ArgAla: 3.171 ± 0.289
1.982ArgCys: 1.982 ± 0.262
2.774ArgAsp: 2.774 ± 0.155
4.36ArgGlu: 4.36 ± 0.989
2.378ArgPhe: 2.378 ± 0.054
5.153ArgGly: 5.153 ± 0.551
0.396ArgHis: 0.396 ± 0.208
2.774ArgIle: 2.774 ± 0.497
4.756ArgLys: 4.756 ± 1.197
3.171ArgLeu: 3.171 ± 0.363
1.189ArgMet: 1.189 ± 0.027
1.585ArgAsn: 1.585 ± 0.182
2.774ArgPro: 2.774 ± 0.497
2.378ArgGln: 2.378 ± 0.599
8.323ArgArg: 8.323 ± 3.073
2.378ArgSer: 2.378 ± 0.599
2.378ArgThr: 2.378 ± 0.599
6.738ArgVal: 6.738 ± 0.369
0.793ArgTrp: 0.793 ± 0.235
3.171ArgTyr: 3.171 ± 0.363
0.0ArgXaa: 0.0 ± 0.0
Ser
7.134SerAla: 7.134 ± 1.144
1.189SerCys: 1.189 ± 0.027
3.567SerAsp: 3.567 ± 0.732
1.585SerGlu: 1.585 ± 0.182
3.567SerPhe: 3.567 ± 2.037
5.945SerGly: 5.945 ± 0.134
0.396SerHis: 0.396 ± 0.208
1.982SerIle: 1.982 ± 0.39
3.171SerLys: 3.171 ± 0.363
7.531SerLeu: 7.531 ± 3.213
1.189SerMet: 1.189 ± 0.625
2.774SerAsn: 2.774 ± 0.497
1.982SerPro: 1.982 ± 0.262
0.793SerGln: 0.793 ± 0.417
3.964SerArg: 3.964 ± 0.524
1.982SerSer: 1.982 ± 0.914
4.36SerThr: 4.36 ± 1.62
4.756SerVal: 4.756 ± 1.849
0.396SerTrp: 0.396 ± 0.444
1.189SerTyr: 1.189 ± 0.027
0.0SerXaa: 0.0 ± 0.0
Thr
7.134ThrAla: 7.134 ± 1.796
1.189ThrCys: 1.189 ± 0.027
4.756ThrAsp: 4.756 ± 0.759
3.567ThrGlu: 3.567 ± 1.224
2.378ThrPhe: 2.378 ± 0.054
6.342ThrGly: 6.342 ± 2.534
0.396ThrHis: 0.396 ± 0.208
3.567ThrIle: 3.567 ± 1.224
5.153ThrLys: 5.153 ± 1.406
4.756ThrLeu: 4.756 ± 0.107
1.189ThrMet: 1.189 ± 0.625
3.964ThrAsn: 3.964 ± 1.176
1.585ThrPro: 1.585 ± 1.122
1.585ThrGln: 1.585 ± 0.182
4.36ThrArg: 4.36 ± 1.641
4.756ThrSer: 4.756 ± 0.107
5.549ThrThr: 5.549 ± 0.342
5.153ThrVal: 5.153 ± 0.101
0.396ThrTrp: 0.396 ± 0.444
2.378ThrTyr: 2.378 ± 0.599
0.0ThrXaa: 0.0 ± 0.0
Val
6.738ValAla: 6.738 ± 1.021
3.171ValCys: 3.171 ± 0.363
5.153ValAsp: 5.153 ± 1.406
6.342ValGlu: 6.342 ± 0.577
3.964ValPhe: 3.964 ± 0.128
3.567ValGly: 3.567 ± 1.384
0.793ValHis: 0.793 ± 0.235
5.549ValIle: 5.549 ± 0.342
5.153ValLys: 5.153 ± 0.101
5.549ValLeu: 5.549 ± 1.614
1.585ValMet: 1.585 ± 0.182
1.982ValAsn: 1.982 ± 0.262
1.982ValPro: 1.982 ± 0.262
2.774ValGln: 2.774 ± 1.149
3.171ValArg: 3.171 ± 0.941
4.36ValSer: 4.36 ± 0.315
9.512ValThr: 9.512 ± 3.046
2.774ValVal: 2.774 ± 0.155
0.396ValTrp: 0.396 ± 0.444
2.774ValTyr: 2.774 ± 0.807
0.0ValXaa: 0.0 ± 0.0
Trp
0.396TrpAla: 0.396 ± 0.444
0.396TrpCys: 0.396 ± 0.444
1.189TrpAsp: 1.189 ± 0.625
0.396TrpGlu: 0.396 ± 0.208
0.793TrpPhe: 0.793 ± 0.235
0.396TrpGly: 0.396 ± 0.208
0.396TrpHis: 0.396 ± 0.208
0.0TrpIle: 0.0 ± 0.0
0.396TrpLys: 0.396 ± 0.444
0.793TrpLeu: 0.793 ± 0.235
0.0TrpMet: 0.0 ± 0.0
0.396TrpAsn: 0.396 ± 0.208
0.396TrpPro: 0.396 ± 0.208
0.0TrpGln: 0.0 ± 0.0
1.189TrpArg: 1.189 ± 0.679
0.793TrpSer: 0.793 ± 0.235
0.0TrpThr: 0.0 ± 0.0
1.189TrpVal: 1.189 ± 0.027
0.0TrpTrp: 0.0 ± 0.0
0.793TrpTyr: 0.793 ± 0.417
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.171TyrAla: 3.171 ± 0.289
0.396TyrCys: 0.396 ± 0.444
1.982TyrAsp: 1.982 ± 0.262
1.585TyrGlu: 1.585 ± 0.834
1.189TyrPhe: 1.189 ± 0.625
4.36TyrGly: 4.36 ± 1.641
0.0TyrHis: 0.0 ± 0.0
0.396TyrIle: 0.396 ± 0.444
0.793TyrLys: 0.793 ± 0.417
3.171TyrLeu: 3.171 ± 0.941
1.982TyrMet: 1.982 ± 0.262
1.189TyrAsn: 1.189 ± 0.625
0.793TyrPro: 0.793 ± 0.417
1.189TyrGln: 1.189 ± 0.679
2.378TyrArg: 2.378 ± 0.706
3.171TyrSer: 3.171 ± 0.941
3.964TyrThr: 3.964 ± 0.524
2.378TyrVal: 2.378 ± 0.599
0.793TyrTrp: 0.793 ± 0.235
1.189TyrTyr: 1.189 ± 0.625
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2524 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski