Amino acid dipepetide frequency for Saprochaete ingens

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.416AlaAla: 9.416 ± 0.287	0.724AlaCys: 0.724 ± 0.016	3.532AlaAsp: 3.532 ± 0.149	3.997AlaGlu: 3.997 ± 0.115	2.572AlaPhe: 2.572 ± 0.034	4.272AlaGly: 4.272 ± 0.048	1.476AlaHis: 1.476 ± 0.022	4.027AlaIle: 4.027 ± 0.038	3.605AlaLys: 3.605 ± 0.04	6.573AlaLeu: 6.573 ± 0.082	1.349AlaMet: 1.349 ± 0.023	2.859AlaAsn: 2.859 ± 0.027	4.191AlaPro: 4.191 ± 0.06	3.189AlaGln: 3.189 ± 0.108	3.598AlaArg: 3.598 ± 0.048	7.892AlaSer: 7.892 ± 0.195	5.349AlaThr: 5.349 ± 0.065	4.565AlaVal: 4.565 ± 0.06	0.641AlaTrp: 0.641 ± 0.014	1.882AlaTyr: 1.882 ± 0.026	0.0AlaXaa: 0.0 ± 0.0
Cys	0.687CysAla: 0.687 ± 0.017	0.179CysCys: 0.179 ± 0.007	0.524CysAsp: 0.524 ± 0.014	0.519CysGlu: 0.519 ± 0.014	0.49CysPhe: 0.49 ± 0.014	0.704CysGly: 0.704 ± 0.017	0.259CysHis: 0.259 ± 0.01	0.628CysIle: 0.628 ± 0.014	0.503CysLys: 0.503 ± 0.012	0.89CysLeu: 0.89 ± 0.019	0.175CysMet: 0.175 ± 0.007	0.412CysAsn: 0.412 ± 0.01	0.449CysPro: 0.449 ± 0.013	0.299CysGln: 0.299 ± 0.01	0.463CysArg: 0.463 ± 0.013	0.836CysSer: 0.836 ± 0.023	0.551CysThr: 0.551 ± 0.013	0.659CysVal: 0.659 ± 0.013	0.106CysTrp: 0.106 ± 0.005	0.302CysTyr: 0.302 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	3.742AspAla: 3.742 ± 0.197	0.453AspCys: 0.453 ± 0.014	5.264AspAsp: 5.264 ± 0.148	4.7AspGlu: 4.7 ± 0.077	2.201AspPhe: 2.201 ± 0.026	2.901AspGly: 2.901 ± 0.036	1.045AspHis: 1.045 ± 0.019	3.133AspIle: 3.133 ± 0.034	2.78AspLys: 2.78 ± 0.067	4.9AspLeu: 4.9 ± 0.047	1.037AspMet: 1.037 ± 0.02	2.651AspAsn: 2.651 ± 0.04	2.746AspPro: 2.746 ± 0.038	1.667AspGln: 1.667 ± 0.024	2.143AspArg: 2.143 ± 0.03	5.066AspSer: 5.066 ± 0.116	2.822AspThr: 2.822 ± 0.034	3.096AspVal: 3.096 ± 0.037	0.521AspTrp: 0.521 ± 0.013	1.785AspTyr: 1.785 ± 0.024	0.0AspXaa: 0.0 ± 0.0
Glu	4.583GluAla: 4.583 ± 0.139	0.514GluCys: 0.514 ± 0.013	4.4GluAsp: 4.4 ± 0.092	6.691GluGlu: 6.691 ± 0.113	2.12GluPhe: 2.12 ± 0.025	2.677GluGly: 2.677 ± 0.032	1.132GluHis: 1.132 ± 0.019	3.52GluIle: 3.52 ± 0.042	4.34GluLys: 4.34 ± 0.06	4.906GluLeu: 4.906 ± 0.051	1.164GluMet: 1.164 ± 0.017	3.152GluAsn: 3.152 ± 0.041	2.521GluPro: 2.521 ± 0.046	2.394GluGln: 2.394 ± 0.039	2.821GluArg: 2.821 ± 0.037	5.763GluSer: 5.763 ± 0.232	3.704GluThr: 3.704 ± 0.042	3.121GluVal: 3.121 ± 0.04	0.631GluTrp: 0.631 ± 0.015	2.019GluTyr: 2.019 ± 0.032	0.0GluXaa: 0.0 ± 0.0
Phe	2.568PheAla: 2.568 ± 0.031	0.461PheCys: 0.461 ± 0.011	2.368PheAsp: 2.368 ± 0.03	2.274PheGlu: 2.274 ± 0.029	1.813PhePhe: 1.813 ± 0.029	2.595PheGly: 2.595 ± 0.036	0.834PheHis: 0.834 ± 0.017	2.125PheIle: 2.125 ± 0.029	1.994PheLys: 1.994 ± 0.028	3.359PheLeu: 3.359 ± 0.039	0.72PheMet: 0.72 ± 0.015	1.833PheAsn: 1.833 ± 0.026	1.803PhePro: 1.803 ± 0.024	1.38PheGln: 1.38 ± 0.021	1.559PheArg: 1.559 ± 0.02	3.88PheSer: 3.88 ± 0.039	2.167PheThr: 2.167 ± 0.025	2.432PheVal: 2.432 ± 0.031	0.502PheTrp: 0.502 ± 0.013	1.238PheTyr: 1.238 ± 0.019	0.0PheXaa: 0.0 ± 0.0
Gly	4.038GlyAla: 4.038 ± 0.056	0.574GlyCys: 0.574 ± 0.016	2.816GlyAsp: 2.816 ± 0.036	2.693GlyGlu: 2.693 ± 0.034	2.375GlyPhe: 2.375 ± 0.033	4.866GlyGly: 4.866 ± 0.079	1.31GlyHis: 1.31 ± 0.022	3.296GlyIle: 3.296 ± 0.037	2.892GlyLys: 2.892 ± 0.038	4.729GlyLeu: 4.729 ± 0.046	1.01GlyMet: 1.01 ± 0.017	2.809GlyAsn: 2.809 ± 0.035	2.781GlyPro: 2.781 ± 0.041	1.72GlyGln: 1.72 ± 0.023	2.468GlyArg: 2.468 ± 0.033	6.719GlySer: 6.719 ± 0.149	3.671GlyThr: 3.671 ± 0.054	3.572GlyVal: 3.572 ± 0.041	0.639GlyTrp: 0.639 ± 0.015	1.908GlyTyr: 1.908 ± 0.029	0.0GlyXaa: 0.0 ± 0.0
His	1.4HisAla: 1.4 ± 0.023	0.215HisCys: 0.215 ± 0.008	1.051HisAsp: 1.051 ± 0.019	1.18HisGlu: 1.18 ± 0.021	0.849HisPhe: 0.849 ± 0.014	1.317HisGly: 1.317 ± 0.022	1.395HisHis: 1.395 ± 0.034	1.328HisIle: 1.328 ± 0.021	1.15HisLys: 1.15 ± 0.018	2.028HisLeu: 2.028 ± 0.025	0.433HisMet: 0.433 ± 0.011	1.161HisAsn: 1.161 ± 0.022	1.349HisPro: 1.349 ± 0.022	1.343HisGln: 1.343 ± 0.036	1.193HisArg: 1.193 ± 0.02	2.137HisSer: 2.137 ± 0.031	1.248HisThr: 1.248 ± 0.022	1.245HisVal: 1.245 ± 0.019	0.196HisTrp: 0.196 ± 0.007	0.72HisTyr: 0.72 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	3.853IleAla: 3.853 ± 0.039	0.635IleCys: 0.635 ± 0.014	3.27IleAsp: 3.27 ± 0.04	3.243IleGlu: 3.243 ± 0.036	2.185IlePhe: 2.185 ± 0.035	2.774IleGly: 2.774 ± 0.036	1.249IleHis: 1.249 ± 0.02	3.03IleIle: 3.03 ± 0.037	3.052IleLys: 3.052 ± 0.038	4.719IleLeu: 4.719 ± 0.048	1.011IleMet: 1.011 ± 0.017	2.726IleAsn: 2.726 ± 0.028	3.35IlePro: 3.35 ± 0.032	2.014IleGln: 2.014 ± 0.028	2.443IleArg: 2.443 ± 0.03	5.466IleSer: 5.466 ± 0.048	3.321IleThr: 3.321 ± 0.036	3.548IleVal: 3.548 ± 0.035	0.555IleTrp: 0.555 ± 0.014	1.736IleTyr: 1.736 ± 0.023	0.0IleXaa: 0.0 ± 0.0
Lys	3.812LysAla: 3.812 ± 0.07	0.527LysCys: 0.527 ± 0.015	3.095LysAsp: 3.095 ± 0.036	4.005LysGlu: 4.005 ± 0.058	1.966LysPhe: 1.966 ± 0.024	2.337LysGly: 2.337 ± 0.03	1.23LysHis: 1.23 ± 0.019	3.174LysIle: 3.174 ± 0.034	4.637LysLys: 4.637 ± 0.068	4.606LysLeu: 4.606 ± 0.047	1.003LysMet: 1.003 ± 0.015	2.81LysAsn: 2.81 ± 0.031	2.89LysPro: 2.89 ± 0.037	2.347LysGln: 2.347 ± 0.03	3.256LysArg: 3.256 ± 0.04	4.797LysSer: 4.797 ± 0.058	3.442LysThr: 3.442 ± 0.038	3.016LysVal: 3.016 ± 0.034	0.532LysTrp: 0.532 ± 0.014	1.844LysTyr: 1.844 ± 0.024	0.0LysXaa: 0.0 ± 0.0
Leu	6.591LeuAla: 6.591 ± 0.059	0.972LeuCys: 0.972 ± 0.019	4.791LeuAsp: 4.791 ± 0.072	5.513LeuGlu: 5.513 ± 0.057	3.309LeuPhe: 3.309 ± 0.038	4.722LeuGly: 4.722 ± 0.043	1.903LeuHis: 1.903 ± 0.028	4.151LeuIle: 4.151 ± 0.045	5.007LeuLys: 5.007 ± 0.048	7.569LeuLeu: 7.569 ± 0.073	1.474LeuMet: 1.474 ± 0.022	3.906LeuAsn: 3.906 ± 0.04	4.928LeuPro: 4.928 ± 0.046	3.68LeuGln: 3.68 ± 0.045	4.469LeuArg: 4.469 ± 0.044	7.979LeuSer: 7.979 ± 0.051	4.868LeuThr: 4.868 ± 0.044	5.061LeuVal: 5.061 ± 0.053	0.86LeuTrp: 0.86 ± 0.018	2.557LeuTyr: 2.557 ± 0.033	0.0LeuXaa: 0.0 ± 0.0
Met	1.552MetAla: 1.552 ± 0.024	0.188MetCys: 0.188 ± 0.007	1.008MetAsp: 1.008 ± 0.02	0.988MetGlu: 0.988 ± 0.015	0.717MetPhe: 0.717 ± 0.017	1.044MetGly: 1.044 ± 0.019	0.353MetHis: 0.353 ± 0.01	0.88MetIle: 0.88 ± 0.017	0.934MetLys: 0.934 ± 0.018	1.545MetLeu: 1.545 ± 0.023	0.409MetMet: 0.409 ± 0.01	0.77MetAsn: 0.77 ± 0.017	0.917MetPro: 0.917 ± 0.017	0.622MetGln: 0.622 ± 0.014	0.877MetArg: 0.877 ± 0.016	1.807MetSer: 1.807 ± 0.022	1.125MetThr: 1.125 ± 0.017	1.109MetVal: 1.109 ± 0.021	0.152MetTrp: 0.152 ± 0.007	0.52MetTyr: 0.52 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	2.881AsnAla: 2.881 ± 0.036	0.46AsnCys: 0.46 ± 0.012	2.792AsnAsp: 2.792 ± 0.038	2.734AsnGlu: 2.734 ± 0.032	1.758AsnPhe: 1.758 ± 0.023	3.222AsnGly: 3.222 ± 0.037	1.187AsnHis: 1.187 ± 0.024	2.898AsnIle: 2.898 ± 0.033	2.707AsnLys: 2.707 ± 0.036	3.775AsnLeu: 3.775 ± 0.036	0.874AsnMet: 0.874 ± 0.017	5.034AsnAsn: 5.034 ± 0.098	2.501AsnPro: 2.501 ± 0.031	1.832AsnGln: 1.832 ± 0.029	1.853AsnArg: 1.853 ± 0.026	5.121AsnSer: 5.121 ± 0.06	3.364AsnThr: 3.364 ± 0.042	2.586AsnVal: 2.586 ± 0.028	0.415AsnTrp: 0.415 ± 0.012	1.404AsnTyr: 1.404 ± 0.022	0.0AsnXaa: 0.0 ± 0.0
Pro	4.198ProAla: 4.198 ± 0.06	0.441ProCys: 0.441 ± 0.016	2.456ProAsp: 2.456 ± 0.029	3.44ProGlu: 3.44 ± 0.04	1.948ProPhe: 1.948 ± 0.024	3.005ProGly: 3.005 ± 0.044	1.228ProHis: 1.228 ± 0.021	2.988ProIle: 2.988 ± 0.031	2.939ProLys: 2.939 ± 0.043	4.602ProLeu: 4.602 ± 0.045	0.796ProMet: 0.796 ± 0.016	2.307ProAsn: 2.307 ± 0.029	4.799ProPro: 4.799 ± 0.088	2.757ProGln: 2.757 ± 0.056	2.32ProArg: 2.32 ± 0.029	6.376ProSer: 6.376 ± 0.07	3.933ProThr: 3.933 ± 0.046	3.605ProVal: 3.605 ± 0.044	0.416ProTrp: 0.416 ± 0.012	1.5ProTyr: 1.5 ± 0.024	0.0ProXaa: 0.0 ± 0.0
Gln	2.942GlnAla: 2.942 ± 0.102	0.304GlnCys: 0.304 ± 0.01	1.792GlnAsp: 1.792 ± 0.024	2.479GlnGlu: 2.479 ± 0.042	1.448GlnPhe: 1.448 ± 0.023	1.809GlnGly: 1.809 ± 0.028	1.393GlnHis: 1.393 ± 0.035	2.083GlnIle: 2.083 ± 0.026	2.314GlnLys: 2.314 ± 0.032	3.548GlnLeu: 3.548 ± 0.046	0.739GlnMet: 0.739 ± 0.016	2.075GlnAsn: 2.075 ± 0.034	2.529GlnPro: 2.529 ± 0.056	8.473GlnGln: 8.473 ± 0.272	1.948GlnArg: 1.948 ± 0.026	3.411GlnSer: 3.411 ± 0.041	2.383GlnThr: 2.383 ± 0.05	2.185GlnVal: 2.185 ± 0.034	0.338GlnTrp: 0.338 ± 0.01	1.302GlnTyr: 1.302 ± 0.022	0.0GlnXaa: 0.0 ± 0.0
Arg	3.42ArgAla: 3.42 ± 0.042	0.439ArgCys: 0.439 ± 0.012	2.427ArgAsp: 2.427 ± 0.033	2.872ArgGlu: 2.872 ± 0.042	1.8ArgPhe: 1.8 ± 0.025	2.513ArgGly: 2.513 ± 0.036	1.195ArgHis: 1.195 ± 0.022	2.564ArgIle: 2.564 ± 0.031	3.063ArgLys: 3.063 ± 0.036	4.119ArgLeu: 4.119 ± 0.04	0.889ArgMet: 0.889 ± 0.019	2.241ArgAsn: 2.241 ± 0.026	2.358ArgPro: 2.358 ± 0.031	1.969ArgGln: 1.969 ± 0.029	3.55ArgArg: 3.55 ± 0.051	3.941ArgSer: 3.941 ± 0.046	2.483ArgThr: 2.483 ± 0.033	2.801ArgVal: 2.801 ± 0.033	0.479ArgTrp: 0.479 ± 0.011	1.53ArgTyr: 1.53 ± 0.025	0.0ArgXaa: 0.0 ± 0.0
Ser	7.604SerAla: 7.604 ± 0.156	0.794SerCys: 0.794 ± 0.019	4.717SerAsp: 4.717 ± 0.071	5.535SerGlu: 5.535 ± 0.21	3.765SerPhe: 3.765 ± 0.037	6.434SerGly: 6.434 ± 0.142	2.169SerHis: 2.169 ± 0.029	5.302SerIle: 5.302 ± 0.047	5.132SerLys: 5.132 ± 0.055	8.322SerLeu: 8.322 ± 0.065	1.559SerMet: 1.559 ± 0.022	5.131SerAsn: 5.131 ± 0.067	6.063SerPro: 6.063 ± 0.073	3.944SerGln: 3.944 ± 0.049	4.298SerArg: 4.298 ± 0.044	20.607SerSer: 20.607 ± 0.834	7.956SerThr: 7.956 ± 0.108	5.688SerVal: 5.688 ± 0.085	0.772SerTrp: 0.772 ± 0.016	2.519SerTyr: 2.519 ± 0.036	0.0SerXaa: 0.0 ± 0.0
Thr	5.024ThrAla: 5.024 ± 0.061	0.598ThrCys: 0.598 ± 0.018	2.733ThrAsp: 2.733 ± 0.032	3.37ThrGlu: 3.37 ± 0.058	2.314ThrPhe: 2.314 ± 0.03	3.984ThrGly: 3.984 ± 0.078	1.258ThrHis: 1.258 ± 0.018	3.564ThrIle: 3.564 ± 0.039	3.231ThrLys: 3.231 ± 0.034	5.393ThrLeu: 5.393 ± 0.05	0.947ThrMet: 0.947 ± 0.017	3.008ThrAsn: 3.008 ± 0.034	4.543ThrPro: 4.543 ± 0.045	2.311ThrGln: 2.311 ± 0.039	2.632ThrArg: 2.632 ± 0.03	7.439ThrSer: 7.439 ± 0.09	6.538ThrThr: 6.538 ± 0.114	4.047ThrVal: 4.047 ± 0.079	0.528ThrTrp: 0.528 ± 0.013	1.589ThrTyr: 1.589 ± 0.025	0.0ThrXaa: 0.0 ± 0.0
Val	4.778ValAla: 4.778 ± 0.052	0.668ValCys: 0.668 ± 0.016	3.319ValAsp: 3.319 ± 0.06	3.747ValGlu: 3.747 ± 0.084	2.445ValPhe: 2.445 ± 0.032	3.307ValGly: 3.307 ± 0.045	1.244ValHis: 1.244 ± 0.02	3.195ValIle: 3.195 ± 0.035	2.97ValLys: 2.97 ± 0.033	5.236ValLeu: 5.236 ± 0.051	1.04ValMet: 1.04 ± 0.016	2.409ValAsn: 2.409 ± 0.025	3.557ValPro: 3.557 ± 0.038	2.071ValGln: 2.071 ± 0.034	2.754ValArg: 2.754 ± 0.034	5.714ValSer: 5.714 ± 0.065	3.743ValThr: 3.743 ± 0.074	4.171ValVal: 4.171 ± 0.048	0.595ValTrp: 0.595 ± 0.014	1.787ValTyr: 1.787 ± 0.026	0.0ValXaa: 0.0 ± 0.0
Trp	0.715TrpAla: 0.715 ± 0.015	0.117TrpCys: 0.117 ± 0.005	0.577TrpAsp: 0.577 ± 0.014	0.558TrpGlu: 0.558 ± 0.011	0.413TrpPhe: 0.413 ± 0.013	0.566TrpGly: 0.566 ± 0.012	0.245TrpHis: 0.245 ± 0.009	0.6TrpIle: 0.6 ± 0.015	0.6TrpLys: 0.6 ± 0.014	0.797TrpLeu: 0.797 ± 0.017	0.203TrpMet: 0.203 ± 0.007	0.51TrpAsn: 0.51 ± 0.011	0.329TrpPro: 0.329 ± 0.01	0.32TrpGln: 0.32 ± 0.011	0.555TrpArg: 0.555 ± 0.013	0.67TrpSer: 0.67 ± 0.013	0.593TrpThr: 0.593 ± 0.015	0.562TrpVal: 0.562 ± 0.015	0.149TrpTrp: 0.149 ± 0.007	0.327TrpTyr: 0.327 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.909TyrAla: 1.909 ± 0.026	0.376TyrCys: 0.376 ± 0.011	1.721TyrAsp: 1.721 ± 0.026	1.634TyrGlu: 1.634 ± 0.024	1.418TyrPhe: 1.418 ± 0.022	1.838TyrGly: 1.838 ± 0.025	0.833TyrHis: 0.833 ± 0.017	1.693TyrIle: 1.693 ± 0.023	1.476TyrLys: 1.476 ± 0.023	2.694TyrLeu: 2.694 ± 0.039	0.688TyrMet: 0.688 ± 0.015	1.594TyrAsn: 1.594 ± 0.022	1.448TyrPro: 1.448 ± 0.024	1.162TyrGln: 1.162 ± 0.021	1.45TyrArg: 1.45 ± 0.018	2.689TyrSer: 2.689 ± 0.032	1.788TyrThr: 1.788 ± 0.026	1.68TyrVal: 1.68 ± 0.025	0.378TyrTrp: 0.378 ± 0.015	1.187TyrTyr: 1.187 ± 0.019	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 6465 proteins (3935327 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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