Thermosulfurimonas dismutans

Taxonomy: cellular organisms; Bacteria; Thermodesulfobacteria; Thermodesulfobacteria; Thermodesulfobacteriales; Thermodesulfobacteriaceae; Thermosulfurimonas

Average proteome isoelectric point is 7.11

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 2157 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A179D583|A0A179D583_9BACT 5 10-methylenetetrahydrofolate reductase OS=Thermosulfurimonas dismutans OX=999894 GN=TDIS_1006 PE=4 SV=1
MM1 pKa = 7.36GGARR5 pKa = 11.84RR6 pKa = 11.84IWVVLGFVVFGLWLLAGGVRR26 pKa = 11.84AEE28 pKa = 4.13EE29 pKa = 4.48AKK31 pKa = 10.52PSADD35 pKa = 3.14FTVDD39 pKa = 3.23VLSQYY44 pKa = 7.35VWRR47 pKa = 11.84GFGLSDD53 pKa = 4.17DD54 pKa = 4.3SVVIQPSMTVSYY66 pKa = 10.76LGAYY70 pKa = 8.55VNLWGNYY77 pKa = 7.82DD78 pKa = 3.66TDD80 pKa = 3.84EE81 pKa = 5.25KK82 pKa = 11.38GSDD85 pKa = 3.23DD86 pKa = 4.63ANWNEE91 pKa = 3.76TDD93 pKa = 3.66FTFGYY98 pKa = 9.17TYY100 pKa = 11.29DD101 pKa = 3.63KK102 pKa = 10.96LPYY105 pKa = 10.54GMSLDD110 pKa = 3.59VGGIYY115 pKa = 10.26YY116 pKa = 10.78ALDD119 pKa = 4.8GIDD122 pKa = 5.12DD123 pKa = 4.08SFEE126 pKa = 4.22LFAGLSATCPKK137 pKa = 10.18TGINFGLTIYY147 pKa = 10.49RR148 pKa = 11.84EE149 pKa = 4.03LSHH152 pKa = 7.15YY153 pKa = 10.11PGTWYY158 pKa = 10.08EE159 pKa = 3.97LSAGRR164 pKa = 11.84DD165 pKa = 3.75FGLPWYY171 pKa = 10.01KK172 pKa = 10.19ATLSLSASAMYY183 pKa = 10.5LDD185 pKa = 4.99SDD187 pKa = 5.02DD188 pKa = 4.23KK189 pKa = 11.47GAYY192 pKa = 8.15PDD194 pKa = 4.7PDD196 pKa = 3.96DD197 pKa = 5.54PNDD200 pKa = 3.73EE201 pKa = 4.29FSGWLYY207 pKa = 10.66LQLGAEE213 pKa = 4.29VSVPVGRR220 pKa = 11.84YY221 pKa = 6.75FTVTPKK227 pKa = 10.51VYY229 pKa = 10.81YY230 pKa = 10.41SFSLSDD236 pKa = 4.13DD237 pKa = 3.85ADD239 pKa = 3.93DD240 pKa = 5.98LIEE243 pKa = 5.25DD244 pKa = 4.45GSWDD248 pKa = 3.38NHH250 pKa = 5.93HH251 pKa = 7.2DD252 pKa = 3.6HH253 pKa = 7.0FFGGVSVSFSFF264 pKa = 4.63

Molecular weight: 29.3 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A179D6P6|A0A179D6P6_9BACT Uncharacterized protein OS=Thermosulfurimonas dismutans OX=999894 GN=TDIS_0283 PE=4 SV=1
MM1 pKa = 7.35KK2 pKa = 9.4RR3 pKa = 11.84TYY5 pKa = 9.91QPSRR9 pKa = 11.84IKK11 pKa = 10.5RR12 pKa = 11.84KK13 pKa = 8.27RR14 pKa = 11.84CHH16 pKa = 5.7GFRR19 pKa = 11.84ARR21 pKa = 11.84MSSRR25 pKa = 11.84SGRR28 pKa = 11.84KK29 pKa = 8.17ILKK32 pKa = 8.31NRR34 pKa = 11.84RR35 pKa = 11.84RR36 pKa = 11.84KK37 pKa = 9.71GRR39 pKa = 11.84WRR41 pKa = 11.84LTVV44 pKa = 3.0

Molecular weight: 5.5 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

2157

0

2157

655638

37

1895

304.0

34.32

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

7.672 ± 0.057

1.063 ± 0.025

4.108 ± 0.043

8.901 ± 0.067

4.867 ± 0.044

7.308 ± 0.049

1.797 ± 0.024

6.035 ± 0.049

6.385 ± 0.06

12.026 ± 0.077

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.773 ± 0.02

2.601 ± 0.032

5.116 ± 0.035

2.402 ± 0.029

7.024 ± 0.05

5.089 ± 0.036

4.23 ± 0.035

7.127 ± 0.044

1.177 ± 0.023

3.298 ± 0.031
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski