Amino acid dipepetide frequency for Human associated cyclovirus 10

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.837AlaAla: 5.837 ± 1.516
1.946AlaCys: 1.946 ± 1.126
0.0AlaAsp: 0.0 ± 0.0
3.891AlaGlu: 3.891 ± 0.195
3.891AlaPhe: 3.891 ± 2.642
0.0AlaGly: 0.0 ± 0.0
0.0AlaHis: 0.0 ± 0.0
3.891AlaIle: 3.891 ± 0.195
5.837AlaLys: 5.837 ± 0.931
3.891AlaLeu: 3.891 ± 2.642
1.946AlaMet: 1.946 ± 1.126
0.0AlaAsn: 0.0 ± 0.0
1.946AlaPro: 1.946 ± 1.126
0.0AlaGln: 0.0 ± 0.0
3.891AlaArg: 3.891 ± 2.642
0.0AlaSer: 0.0 ± 0.0
1.946AlaThr: 1.946 ± 1.321
7.782AlaVal: 7.782 ± 5.284
0.0AlaTrp: 0.0 ± 0.0
1.946AlaTyr: 1.946 ± 1.321
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
3.891CysAsp: 3.891 ± 2.252
1.946CysGlu: 1.946 ± 1.126
1.946CysPhe: 1.946 ± 1.126
1.946CysGly: 1.946 ± 1.321
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
3.891CysLys: 3.891 ± 0.195
1.946CysLeu: 1.946 ± 1.321
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
1.946CysPro: 1.946 ± 1.126
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
3.891CysSer: 3.891 ± 2.252
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
1.946CysTyr: 1.946 ± 1.126
0.0CysXaa: 0.0 ± 0.0
Asp
3.891AspAla: 3.891 ± 2.642
1.946AspCys: 1.946 ± 1.126
1.946AspAsp: 1.946 ± 1.126
1.946AspGlu: 1.946 ± 1.126
3.891AspPhe: 3.891 ± 0.195
3.891AspGly: 3.891 ± 2.252
0.0AspHis: 0.0 ± 0.0
5.837AspIle: 5.837 ± 0.931
5.837AspLys: 5.837 ± 1.516
1.946AspLeu: 1.946 ± 1.126
1.946AspMet: 1.946 ± 1.321
0.0AspAsn: 0.0 ± 0.0
0.0AspPro: 0.0 ± 0.0
0.0AspGln: 0.0 ± 0.0
3.891AspArg: 3.891 ± 2.252
0.0AspSer: 0.0 ± 0.0
1.946AspThr: 1.946 ± 1.126
5.837AspVal: 5.837 ± 0.931
0.0AspTrp: 0.0 ± 0.0
1.946AspTyr: 1.946 ± 1.126
0.0AspXaa: 0.0 ± 0.0
Glu
5.837GluAla: 5.837 ± 3.963
0.0GluCys: 0.0 ± 0.0
1.946GluAsp: 1.946 ± 1.126
5.837GluGlu: 5.837 ± 0.931
5.837GluPhe: 5.837 ± 0.931
1.946GluGly: 1.946 ± 1.126
1.946GluHis: 1.946 ± 1.126
0.0GluIle: 0.0 ± 0.0
5.837GluLys: 5.837 ± 3.378
3.891GluLeu: 3.891 ± 0.195
0.0GluMet: 0.0 ± 0.0
5.837GluAsn: 5.837 ± 0.931
0.0GluPro: 0.0 ± 0.0
1.946GluGln: 1.946 ± 1.126
0.0GluArg: 0.0 ± 0.0
5.837GluSer: 5.837 ± 0.931
3.891GluThr: 3.891 ± 0.195
3.891GluVal: 3.891 ± 2.252
1.946GluTrp: 1.946 ± 1.126
3.891GluTyr: 3.891 ± 2.642
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
3.891PheCys: 3.891 ± 2.252
0.0PheAsp: 0.0 ± 0.0
7.782PheGlu: 7.782 ± 0.39
1.946PhePhe: 1.946 ± 1.126
1.946PheGly: 1.946 ± 1.126
0.0PheHis: 0.0 ± 0.0
3.891PheIle: 3.891 ± 2.252
5.837PheLys: 5.837 ± 0.931
1.946PheLeu: 1.946 ± 1.321
1.946PheMet: 1.946 ± 1.321
1.946PheAsn: 1.946 ± 1.126
1.946PhePro: 1.946 ± 1.321
3.891PheGln: 3.891 ± 2.642
0.0PheArg: 0.0 ± 0.0
1.946PheSer: 1.946 ± 1.321
5.837PheThr: 5.837 ± 0.931
1.946PheVal: 1.946 ± 1.321
0.0PheTrp: 0.0 ± 0.0
3.891PheTyr: 3.891 ± 0.195
0.0PheXaa: 0.0 ± 0.0
Gly
0.0GlyAla: 0.0 ± 0.0
0.0GlyCys: 0.0 ± 0.0
3.891GlyAsp: 3.891 ± 2.642
5.837GlyGlu: 5.837 ± 3.378
3.891GlyPhe: 3.891 ± 2.252
3.891GlyGly: 3.891 ± 2.252
0.0GlyHis: 0.0 ± 0.0
7.782GlyIle: 7.782 ± 0.39
3.891GlyLys: 3.891 ± 2.252
3.891GlyLeu: 3.891 ± 0.195
1.946GlyMet: 1.946 ± 1.321
0.0GlyAsn: 0.0 ± 0.0
1.946GlyPro: 1.946 ± 1.126
1.946GlyGln: 1.946 ± 1.126
0.0GlyArg: 0.0 ± 0.0
7.782GlySer: 7.782 ± 4.503
7.782GlyThr: 7.782 ± 2.837
0.0GlyVal: 0.0 ± 0.0
1.946GlyTrp: 1.946 ± 1.126
3.891GlyTyr: 3.891 ± 2.252
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
1.946HisCys: 1.946 ± 1.126
3.891HisAsp: 3.891 ± 2.252
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
1.946HisIle: 1.946 ± 1.126
3.891HisLys: 3.891 ± 0.195
1.946HisLeu: 1.946 ± 1.126
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
1.946HisPro: 1.946 ± 1.126
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
0.0HisSer: 0.0 ± 0.0
0.0HisThr: 0.0 ± 0.0
3.891HisVal: 3.891 ± 2.642
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
1.946IleAla: 1.946 ± 1.126
1.946IleCys: 1.946 ± 1.126
7.782IleAsp: 7.782 ± 0.39
1.946IleGlu: 1.946 ± 1.126
3.891IlePhe: 3.891 ± 2.252
5.837IleGly: 5.837 ± 3.963
3.891IleHis: 3.891 ± 2.252
5.837IleIle: 5.837 ± 0.931
9.728IleLys: 9.728 ± 3.182
0.0IleLeu: 0.0 ± 0.0
1.946IleMet: 1.946 ± 0.098
3.891IleAsn: 3.891 ± 0.195
3.891IlePro: 3.891 ± 2.642
7.782IleGln: 7.782 ± 0.39
7.782IleArg: 7.782 ± 2.057
0.0IleSer: 0.0 ± 0.0
3.891IleThr: 3.891 ± 2.252
1.946IleVal: 1.946 ± 1.321
0.0IleTrp: 0.0 ± 0.0
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
5.837LysAla: 5.837 ± 1.516
0.0LysCys: 0.0 ± 0.0
1.946LysAsp: 1.946 ± 1.321
7.782LysGlu: 7.782 ± 4.503
1.946LysPhe: 1.946 ± 1.126
3.891LysGly: 3.891 ± 2.252
1.946LysHis: 1.946 ± 1.126
1.946LysIle: 1.946 ± 1.126
1.946LysLys: 1.946 ± 1.321
1.946LysLeu: 1.946 ± 1.321
0.0LysMet: 0.0 ± 0.0
0.0LysAsn: 0.0 ± 0.0
9.728LysPro: 9.728 ± 1.711
0.0LysGln: 0.0 ± 0.0
5.837LysArg: 5.837 ± 1.516
5.837LysSer: 5.837 ± 0.931
5.837LysThr: 5.837 ± 0.931
5.837LysVal: 5.837 ± 1.516
3.891LysTrp: 3.891 ± 0.195
7.782LysTyr: 7.782 ± 2.057
0.0LysXaa: 0.0 ± 0.0
Leu
1.946LeuAla: 1.946 ± 1.126
0.0LeuCys: 0.0 ± 0.0
1.946LeuAsp: 1.946 ± 1.126
5.837LeuGlu: 5.837 ± 0.931
0.0LeuPhe: 0.0 ± 0.0
0.0LeuGly: 0.0 ± 0.0
0.0LeuHis: 0.0 ± 0.0
1.946LeuIle: 1.946 ± 1.321
3.891LeuLys: 3.891 ± 0.195
5.837LeuLeu: 5.837 ± 3.378
0.0LeuMet: 0.0 ± 0.0
5.837LeuAsn: 5.837 ± 1.516
0.0LeuPro: 0.0 ± 0.0
3.891LeuGln: 3.891 ± 0.195
1.946LeuArg: 1.946 ± 1.321
3.891LeuSer: 3.891 ± 0.195
1.946LeuThr: 1.946 ± 1.321
3.891LeuVal: 3.891 ± 0.195
0.0LeuTrp: 0.0 ± 0.0
3.891LeuTyr: 3.891 ± 0.195
0.0LeuXaa: 0.0 ± 0.0
Met
1.946MetAla: 1.946 ± 1.321
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
0.0MetGlu: 0.0 ± 0.0
0.0MetPhe: 0.0 ± 0.0
1.946MetGly: 1.946 ± 1.126
0.0MetHis: 0.0 ± 0.0
3.891MetIle: 3.891 ± 2.642
0.0MetLys: 0.0 ± 0.0
1.946MetLeu: 1.946 ± 1.321
0.0MetMet: 0.0 ± 0.0
3.891MetAsn: 3.891 ± 0.195
0.0MetPro: 0.0 ± 0.0
1.946MetGln: 1.946 ± 1.126
1.946MetArg: 1.946 ± 1.321
0.0MetSer: 0.0 ± 0.0
0.0MetThr: 0.0 ± 0.0
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
0.0AsnAla: 0.0 ± 0.0
0.0AsnCys: 0.0 ± 0.0
3.891AsnAsp: 3.891 ± 2.642
1.946AsnGlu: 1.946 ± 1.321
3.891AsnPhe: 3.891 ± 0.195
1.946AsnGly: 1.946 ± 1.126
0.0AsnHis: 0.0 ± 0.0
1.946AsnIle: 1.946 ± 1.126
0.0AsnLys: 0.0 ± 0.0
3.891AsnLeu: 3.891 ± 0.195
0.0AsnMet: 0.0 ± 0.0
1.946AsnAsn: 1.946 ± 1.321
0.0AsnPro: 0.0 ± 0.0
3.891AsnGln: 3.891 ± 0.195
1.946AsnArg: 1.946 ± 1.126
5.837AsnSer: 5.837 ± 1.516
1.946AsnThr: 1.946 ± 1.126
5.837AsnVal: 5.837 ± 1.516
0.0AsnTrp: 0.0 ± 0.0
5.837AsnTyr: 5.837 ± 3.963
0.0AsnXaa: 0.0 ± 0.0
Pro
3.891ProAla: 3.891 ± 0.195
0.0ProCys: 0.0 ± 0.0
3.891ProAsp: 3.891 ± 0.195
1.946ProGlu: 1.946 ± 1.321
1.946ProPhe: 1.946 ± 1.321
3.891ProGly: 3.891 ± 0.195
1.946ProHis: 1.946 ± 1.126
1.946ProIle: 1.946 ± 1.126
1.946ProLys: 1.946 ± 1.126
0.0ProLeu: 0.0 ± 0.0
0.0ProMet: 0.0 ± 0.0
0.0ProAsn: 0.0 ± 0.0
1.946ProPro: 1.946 ± 1.126
0.0ProGln: 0.0 ± 0.0
5.837ProArg: 5.837 ± 0.931
3.891ProSer: 3.891 ± 0.195
1.946ProThr: 1.946 ± 1.321
3.891ProVal: 3.891 ± 0.195
1.946ProTrp: 1.946 ± 1.321
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
3.891GlnAla: 3.891 ± 2.642
0.0GlnCys: 0.0 ± 0.0
0.0GlnAsp: 0.0 ± 0.0
0.0GlnGlu: 0.0 ± 0.0
3.891GlnPhe: 3.891 ± 2.642
5.837GlnGly: 5.837 ± 0.931
0.0GlnHis: 0.0 ± 0.0
0.0GlnIle: 0.0 ± 0.0
0.0GlnLys: 0.0 ± 0.0
3.891GlnLeu: 3.891 ± 0.195
0.0GlnMet: 0.0 ± 0.0
1.946GlnAsn: 1.946 ± 1.321
1.946GlnPro: 1.946 ± 1.321
5.837GlnGln: 5.837 ± 0.931
5.837GlnArg: 5.837 ± 1.516
1.946GlnSer: 1.946 ± 1.126
3.891GlnThr: 3.891 ± 0.195
1.946GlnVal: 1.946 ± 1.321
0.0GlnTrp: 0.0 ± 0.0
1.946GlnTyr: 1.946 ± 1.126
0.0GlnXaa: 0.0 ± 0.0
Arg
1.946ArgAla: 1.946 ± 1.321
0.0ArgCys: 0.0 ± 0.0
0.0ArgAsp: 0.0 ± 0.0
0.0ArgGlu: 0.0 ± 0.0
7.782ArgPhe: 7.782 ± 0.39
5.837ArgGly: 5.837 ± 0.931
0.0ArgHis: 0.0 ± 0.0
13.619ArgIle: 13.619 ± 0.54
1.946ArgLys: 1.946 ± 1.321
0.0ArgLeu: 0.0 ± 0.0
0.0ArgMet: 0.0 ± 0.0
1.946ArgAsn: 1.946 ± 1.126
1.946ArgPro: 1.946 ± 1.321
0.0ArgGln: 0.0 ± 0.0
25.292ArgArg: 25.292 ± 4.939
5.837ArgSer: 5.837 ± 0.931
3.891ArgThr: 3.891 ± 0.195
3.891ArgVal: 3.891 ± 2.642
0.0ArgTrp: 0.0 ± 0.0
11.673ArgTyr: 11.673 ± 0.586
0.0ArgXaa: 0.0 ± 0.0
Ser
0.0SerAla: 0.0 ± 0.0
0.0SerCys: 0.0 ± 0.0
1.946SerAsp: 1.946 ± 1.126
3.891SerGlu: 3.891 ± 0.195
5.837SerPhe: 5.837 ± 1.516
7.782SerGly: 7.782 ± 4.503
0.0SerHis: 0.0 ± 0.0
1.946SerIle: 1.946 ± 1.321
3.891SerLys: 3.891 ± 2.252
5.837SerLeu: 5.837 ± 3.378
3.891SerMet: 3.891 ± 2.642
5.837SerAsn: 5.837 ± 0.931
3.891SerPro: 3.891 ± 2.252
1.946SerGln: 1.946 ± 1.321
5.837SerArg: 5.837 ± 1.516
3.891SerSer: 3.891 ± 0.195
1.946SerThr: 1.946 ± 1.321
3.891SerVal: 3.891 ± 2.252
0.0SerTrp: 0.0 ± 0.0
1.946SerTyr: 1.946 ± 1.126
0.0SerXaa: 0.0 ± 0.0
Thr
5.837ThrAla: 5.837 ± 1.516
1.946ThrCys: 1.946 ± 1.321
1.946ThrAsp: 1.946 ± 1.126
5.837ThrGlu: 5.837 ± 0.931
0.0ThrPhe: 0.0 ± 0.0
3.891ThrGly: 3.891 ± 2.642
1.946ThrHis: 1.946 ± 1.126
3.891ThrIle: 3.891 ± 2.252
1.946ThrLys: 1.946 ± 1.321
0.0ThrLeu: 0.0 ± 0.0
0.0ThrMet: 0.0 ± 0.0
1.946ThrAsn: 1.946 ± 1.321
0.0ThrPro: 0.0 ± 0.0
3.891ThrGln: 3.891 ± 2.642
1.946ThrArg: 1.946 ± 1.126
7.782ThrSer: 7.782 ± 2.057
5.837ThrThr: 5.837 ± 1.516
3.891ThrVal: 3.891 ± 0.195
1.946ThrTrp: 1.946 ± 1.126
1.946ThrTyr: 1.946 ± 1.321
0.0ThrXaa: 0.0 ± 0.0
Val
3.891ValAla: 3.891 ± 2.252
3.891ValCys: 3.891 ± 2.252
1.946ValAsp: 1.946 ± 1.126
3.891ValGlu: 3.891 ± 2.642
0.0ValPhe: 0.0 ± 0.0
0.0ValGly: 0.0 ± 0.0
1.946ValHis: 1.946 ± 1.321
5.837ValIle: 5.837 ± 1.516
5.837ValLys: 5.837 ± 3.963
0.0ValLeu: 0.0 ± 0.0
0.0ValMet: 0.0 ± 0.0
7.782ValAsn: 7.782 ± 5.284
5.837ValPro: 5.837 ± 1.516
3.891ValGln: 3.891 ± 2.642
5.837ValArg: 5.837 ± 0.931
3.891ValSer: 3.891 ± 0.195
1.946ValThr: 1.946 ± 1.321
3.891ValVal: 3.891 ± 0.195
0.0ValTrp: 0.0 ± 0.0
3.891ValTyr: 3.891 ± 0.195
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
1.946TrpAsp: 1.946 ± 1.126
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
1.946TrpGly: 1.946 ± 1.126
3.891TrpHis: 3.891 ± 0.195
3.891TrpIle: 3.891 ± 2.252
1.946TrpLys: 1.946 ± 1.321
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
1.946TrpTrp: 1.946 ± 1.126
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.946TyrAla: 1.946 ± 1.321
5.837TyrCys: 5.837 ± 1.516
3.891TyrAsp: 3.891 ± 2.252
0.0TyrGlu: 0.0 ± 0.0
0.0TyrPhe: 0.0 ± 0.0
3.891TyrGly: 3.891 ± 2.252
1.946TyrHis: 1.946 ± 1.321
5.837TyrIle: 5.837 ± 0.931
5.837TyrLys: 5.837 ± 0.931
3.891TyrLeu: 3.891 ± 0.195
1.946TyrMet: 1.946 ± 1.126
1.946TyrAsn: 1.946 ± 1.321
1.946TyrPro: 1.946 ± 1.126
1.946TyrGln: 1.946 ± 1.321
7.782TyrArg: 7.782 ± 2.837
1.946TyrSer: 1.946 ± 1.321
1.946TyrThr: 1.946 ± 1.126
1.946TyrVal: 1.946 ± 1.321
1.946TyrTrp: 1.946 ± 1.126
7.782TyrTyr: 7.782 ± 2.057
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (515 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski