Amino acid dipepetide frequency for Trichoderma asperellum dsRNA virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
12.367AlaAla: 12.367 ± 4.434
1.413AlaCys: 1.413 ± 0.592
3.887AlaAsp: 3.887 ± 1.138
3.534AlaGlu: 3.534 ± 0.163
5.3AlaPhe: 5.3 ± 1.599
4.947AlaGly: 4.947 ± 1.352
2.473AlaHis: 2.473 ± 0.676
5.654AlaIle: 5.654 ± 0.787
3.18AlaLys: 3.18 ± 0.937
8.834AlaLeu: 8.834 ± 0.91
1.413AlaMet: 1.413 ± 0.065
4.594AlaAsn: 4.594 ± 1.002
4.24AlaPro: 4.24 ± 1.912
5.3AlaGln: 5.3 ± 0.019
5.654AlaArg: 5.654 ± 1.32
6.714AlaSer: 6.714 ± 0.481
3.534AlaThr: 3.534 ± 0.69
6.714AlaVal: 6.714 ± 1.008
1.767AlaTrp: 1.767 ± 0.709
2.827AlaTyr: 2.827 ± 0.923
0.0AlaXaa: 0.0 ± 0.0
Cys
1.06CysAla: 1.06 ± 0.312
0.353CysCys: 0.353 ± 0.28
0.707CysAsp: 0.707 ± 0.559
0.707CysGlu: 0.707 ± 0.033
0.353CysPhe: 0.353 ± 0.247
1.413CysGly: 1.413 ± 0.065
0.0CysHis: 0.0 ± 0.0
0.353CysIle: 0.353 ± 0.28
0.353CysLys: 0.353 ± 0.28
1.767CysLeu: 1.767 ± 0.709
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.353CysArg: 0.353 ± 0.28
0.707CysSer: 0.707 ± 0.033
0.0CysThr: 0.0 ± 0.0
0.353CysVal: 0.353 ± 0.247
0.353CysTrp: 0.353 ± 0.247
0.353CysTyr: 0.353 ± 0.28
0.0CysXaa: 0.0 ± 0.0
Asp
5.3AspAla: 5.3 ± 0.508
0.0AspCys: 0.0 ± 0.0
4.24AspAsp: 4.24 ± 0.195
2.827AspGlu: 2.827 ± 0.13
4.947AspPhe: 4.947 ± 1.282
2.827AspGly: 2.827 ± 0.13
0.707AspHis: 0.707 ± 0.559
3.887AspIle: 3.887 ± 0.443
1.767AspLys: 1.767 ± 0.872
6.36AspLeu: 6.36 ± 2.927
0.707AspMet: 0.707 ± 0.374
1.767AspAsn: 1.767 ± 0.345
2.12AspPro: 2.12 ± 0.098
1.767AspGln: 1.767 ± 0.182
1.767AspArg: 1.767 ± 0.709
4.947AspSer: 4.947 ± 0.228
3.18AspThr: 3.18 ± 1.464
2.473AspVal: 2.473 ± 0.149
1.413AspTrp: 1.413 ± 0.462
2.12AspTyr: 2.12 ± 0.956
0.0AspXaa: 0.0 ± 0.0
Glu
4.24GluAla: 4.24 ± 0.331
0.353GluCys: 0.353 ± 0.28
2.827GluAsp: 2.827 ± 0.13
3.18GluGlu: 3.18 ± 1.17
2.473GluPhe: 2.473 ± 0.149
1.767GluGly: 1.767 ± 0.182
1.06GluHis: 1.06 ± 0.839
2.827GluIle: 2.827 ± 0.396
0.353GluLys: 0.353 ± 0.247
7.067GluLeu: 7.067 ± 1.781
2.12GluMet: 2.12 ± 0.429
2.12GluAsn: 2.12 ± 0.625
1.06GluPro: 1.06 ± 0.215
1.767GluGln: 1.767 ± 0.182
2.827GluArg: 2.827 ± 0.396
2.473GluSer: 2.473 ± 0.149
2.827GluThr: 2.827 ± 0.657
2.473GluVal: 2.473 ± 0.149
0.353GluTrp: 0.353 ± 0.28
2.12GluTyr: 2.12 ± 0.429
0.0GluXaa: 0.0 ± 0.0
Phe
2.12PheAla: 2.12 ± 0.429
0.353PheCys: 0.353 ± 0.28
2.827PheAsp: 2.827 ± 1.711
2.473PheGlu: 2.473 ± 0.904
2.473PhePhe: 2.473 ± 0.149
2.827PheGly: 2.827 ± 0.923
0.0PheHis: 0.0 ± 0.0
3.18PheIle: 3.18 ± 0.117
2.12PheLys: 2.12 ± 0.098
3.887PheLeu: 3.887 ± 0.443
1.767PheMet: 1.767 ± 0.182
3.887PheAsn: 3.887 ± 0.443
1.06PhePro: 1.06 ± 0.215
1.767PheGln: 1.767 ± 0.709
2.473PheArg: 2.473 ± 0.149
4.594PheSer: 4.594 ± 0.578
2.473PheThr: 2.473 ± 0.149
1.06PheVal: 1.06 ± 0.215
1.06PheTrp: 1.06 ± 0.312
0.707PheTyr: 0.707 ± 0.033
0.0PheXaa: 0.0 ± 0.0
Gly
4.24GlyAla: 4.24 ± 0.195
1.413GlyCys: 1.413 ± 0.462
3.18GlyAsp: 3.18 ± 0.41
3.534GlyGlu: 3.534 ± 0.163
2.473GlyPhe: 2.473 ± 0.149
6.007GlyGly: 6.007 ± 1.04
3.887GlyHis: 3.887 ± 0.611
2.827GlyIle: 2.827 ± 0.657
5.3GlyLys: 5.3 ± 1.073
4.594GlyLeu: 4.594 ± 0.578
2.12GlyMet: 2.12 ± 0.429
3.18GlyAsn: 3.18 ± 0.644
0.707GlyPro: 0.707 ± 0.033
3.534GlyGln: 3.534 ± 0.364
3.887GlyArg: 3.887 ± 0.969
3.887GlySer: 3.887 ± 0.611
3.18GlyThr: 3.18 ± 0.644
3.887GlyVal: 3.887 ± 0.443
0.353GlyTrp: 0.353 ± 0.247
2.473GlyTyr: 2.473 ± 0.904
0.0GlyXaa: 0.0 ± 0.0
His
1.767HisAla: 1.767 ± 0.182
0.0HisCys: 0.0 ± 0.0
0.707HisAsp: 0.707 ± 0.033
0.707HisGlu: 0.707 ± 0.559
1.413HisPhe: 1.413 ± 0.988
1.413HisGly: 1.413 ± 0.592
0.707HisHis: 0.707 ± 0.033
2.12HisIle: 2.12 ± 0.429
0.707HisLys: 0.707 ± 0.494
1.413HisLeu: 1.413 ± 0.065
0.353HisMet: 0.353 ± 0.247
1.06HisAsn: 1.06 ± 0.215
1.413HisPro: 1.413 ± 0.065
0.353HisGln: 0.353 ± 0.247
1.413HisArg: 1.413 ± 0.462
0.707HisSer: 0.707 ± 0.559
1.06HisThr: 1.06 ± 0.312
1.767HisVal: 1.767 ± 0.182
1.413HisTrp: 1.413 ± 0.065
2.473HisTyr: 2.473 ± 0.149
0.0HisXaa: 0.0 ± 0.0
Ile
3.534IleAla: 3.534 ± 0.364
0.707IleCys: 0.707 ± 0.559
4.947IleAsp: 4.947 ± 0.755
0.707IleGlu: 0.707 ± 0.494
1.767IlePhe: 1.767 ± 1.398
2.827IleGly: 2.827 ± 0.657
1.767IleHis: 1.767 ± 0.345
2.473IleIle: 2.473 ± 0.904
2.473IleLys: 2.473 ± 0.377
3.534IleLeu: 3.534 ± 0.69
1.06IleMet: 1.06 ± 0.215
5.3IleAsn: 5.3 ± 0.508
3.887IlePro: 3.887 ± 0.084
2.12IleGln: 2.12 ± 0.625
2.827IleArg: 2.827 ± 0.923
2.827IleSer: 2.827 ± 0.923
4.947IleThr: 4.947 ± 0.228
3.18IleVal: 3.18 ± 0.41
0.353IleTrp: 0.353 ± 0.28
2.473IleTyr: 2.473 ± 0.377
0.353IleXaa: 0.353 ± 0.28
Lys
2.473LysAla: 2.473 ± 0.149
0.353LysCys: 0.353 ± 0.247
2.827LysAsp: 2.827 ± 0.657
1.413LysGlu: 1.413 ± 0.462
2.12LysPhe: 2.12 ± 0.429
1.06LysGly: 1.06 ± 0.215
1.06LysHis: 1.06 ± 0.839
1.413LysIle: 1.413 ± 0.592
0.707LysLys: 0.707 ± 0.033
6.007LysLeu: 6.007 ± 0.54
1.06LysMet: 1.06 ± 0.215
1.413LysAsn: 1.413 ± 0.592
1.413LysPro: 1.413 ± 1.119
1.06LysGln: 1.06 ± 0.215
2.827LysArg: 2.827 ± 1.184
1.767LysSer: 1.767 ± 0.182
4.594LysThr: 4.594 ± 1.002
3.18LysVal: 3.18 ± 0.41
0.707LysTrp: 0.707 ± 0.033
2.827LysTyr: 2.827 ± 1.184
0.0LysXaa: 0.0 ± 0.0
Leu
10.601LeuAla: 10.601 ± 1.092
0.707LeuCys: 0.707 ± 0.033
4.594LeuAsp: 4.594 ± 0.578
3.887LeuGlu: 3.887 ± 1.138
1.767LeuPhe: 1.767 ± 0.872
7.42LeuGly: 7.42 ± 0.079
1.767LeuHis: 1.767 ± 0.182
4.947LeuIle: 4.947 ± 1.282
4.594LeuLys: 4.594 ± 0.475
8.127LeuLeu: 8.127 ± 2.218
2.827LeuMet: 2.827 ± 1.711
4.947LeuAsn: 4.947 ± 0.228
7.774LeuPro: 7.774 ± 1.749
4.24LeuGln: 4.24 ± 0.858
6.714LeuArg: 6.714 ± 2.153
7.774LeuSer: 7.774 ± 0.358
8.127LeuThr: 8.127 ± 1.692
3.18LeuVal: 3.18 ± 1.464
1.767LeuTrp: 1.767 ± 0.709
1.767LeuTyr: 1.767 ± 1.398
0.353LeuXaa: 0.353 ± 0.247
Met
1.767MetAla: 1.767 ± 1.236
0.353MetCys: 0.353 ± 0.28
0.0MetAsp: 0.0 ± 0.0
1.413MetGlu: 1.413 ± 0.462
0.353MetPhe: 0.353 ± 0.28
1.06MetGly: 1.06 ± 0.312
0.353MetHis: 0.353 ± 0.247
0.707MetIle: 0.707 ± 0.494
0.353MetLys: 0.353 ± 0.247
4.947MetLeu: 4.947 ± 2.335
1.413MetMet: 1.413 ± 0.065
0.707MetAsn: 0.707 ± 0.033
0.707MetPro: 0.707 ± 0.559
0.353MetGln: 0.353 ± 0.28
2.473MetArg: 2.473 ± 0.377
1.767MetSer: 1.767 ± 0.709
1.06MetThr: 1.06 ± 0.741
1.06MetVal: 1.06 ± 0.215
0.707MetTrp: 0.707 ± 0.033
0.353MetTyr: 0.353 ± 0.28
0.0MetXaa: 0.0 ± 0.0
Asn
7.067AsnAla: 7.067 ± 1.781
0.0AsnCys: 0.0 ± 0.0
3.534AsnAsp: 3.534 ± 0.69
1.413AsnGlu: 1.413 ± 0.065
1.767AsnPhe: 1.767 ± 0.345
3.18AsnGly: 3.18 ± 2.224
1.413AsnHis: 1.413 ± 0.065
1.413AsnIle: 1.413 ± 1.119
2.473AsnLys: 2.473 ± 1.431
4.947AsnLeu: 4.947 ± 1.808
0.707AsnMet: 0.707 ± 0.388
3.534AsnAsn: 3.534 ± 0.891
2.12AsnPro: 2.12 ± 0.429
1.413AsnGln: 1.413 ± 0.462
4.24AsnArg: 4.24 ± 0.331
2.827AsnSer: 2.827 ± 0.657
3.534AsnThr: 3.534 ± 0.163
2.473AsnVal: 2.473 ± 0.904
0.707AsnTrp: 0.707 ± 0.033
2.473AsnTyr: 2.473 ± 0.904
0.0AsnXaa: 0.0 ± 0.0
Pro
3.534ProAla: 3.534 ± 0.891
0.353ProCys: 0.353 ± 0.247
0.353ProAsp: 0.353 ± 0.247
2.827ProGlu: 2.827 ± 0.923
2.473ProPhe: 2.473 ± 0.377
3.887ProGly: 3.887 ± 0.611
1.06ProHis: 1.06 ± 0.741
2.473ProIle: 2.473 ± 0.377
2.473ProLys: 2.473 ± 0.904
2.473ProLeu: 2.473 ± 0.676
0.0ProMet: 0.0 ± 0.0
2.12ProAsn: 2.12 ± 0.429
3.18ProPro: 3.18 ± 0.644
2.827ProGln: 2.827 ± 0.657
3.18ProArg: 3.18 ± 1.697
3.887ProSer: 3.887 ± 0.611
4.24ProThr: 4.24 ± 0.331
4.24ProVal: 4.24 ± 0.331
0.707ProTrp: 0.707 ± 0.033
2.12ProTyr: 2.12 ± 0.429
0.0ProXaa: 0.0 ± 0.0
Gln
5.3GlnAla: 5.3 ± 2.126
0.353GlnCys: 0.353 ± 0.247
2.473GlnAsp: 2.473 ± 0.377
2.12GlnGlu: 2.12 ± 0.098
1.767GlnPhe: 1.767 ± 0.182
2.473GlnGly: 2.473 ± 0.149
2.12GlnHis: 2.12 ± 0.098
2.827GlnIle: 2.827 ± 0.13
0.707GlnLys: 0.707 ± 0.559
4.24GlnLeu: 4.24 ± 0.331
0.0GlnMet: 0.0 ± 0.0
1.413GlnAsn: 1.413 ± 0.592
2.473GlnPro: 2.473 ± 0.149
1.767GlnGln: 1.767 ± 0.709
2.12GlnArg: 2.12 ± 0.429
3.18GlnSer: 3.18 ± 1.17
3.534GlnThr: 3.534 ± 1.944
4.24GlnVal: 4.24 ± 1.249
1.06GlnTrp: 1.06 ± 0.312
0.353GlnTyr: 0.353 ± 0.28
0.0GlnXaa: 0.0 ± 0.0
Arg
7.067ArgAla: 7.067 ± 0.853
0.707ArgCys: 0.707 ± 0.494
2.473ArgAsp: 2.473 ± 0.676
3.887ArgGlu: 3.887 ± 1.665
2.12ArgPhe: 2.12 ± 0.098
3.534ArgGly: 3.534 ± 1.743
0.0ArgHis: 0.0 ± 0.0
2.473ArgIle: 2.473 ± 0.676
1.06ArgLys: 1.06 ± 0.215
8.127ArgLeu: 8.127 ± 0.416
1.413ArgMet: 1.413 ± 0.065
3.534ArgAsn: 3.534 ± 0.891
2.827ArgPro: 2.827 ± 0.396
4.24ArgGln: 4.24 ± 0.195
3.534ArgArg: 3.534 ± 1.216
3.18ArgSer: 3.18 ± 0.41
5.3ArgThr: 5.3 ± 0.019
5.3ArgVal: 5.3 ± 1.073
0.0ArgTrp: 0.0 ± 0.0
2.473ArgTyr: 2.473 ± 0.377
0.353ArgXaa: 0.353 ± 0.28
Ser
5.3SerAla: 5.3 ± 0.546
0.0SerCys: 0.0 ± 0.0
3.18SerAsp: 3.18 ± 0.937
5.3SerGlu: 5.3 ± 0.019
2.12SerPhe: 2.12 ± 0.098
5.654SerGly: 5.654 ± 0.793
1.06SerHis: 1.06 ± 0.741
4.24SerIle: 4.24 ± 0.722
3.534SerLys: 3.534 ± 0.891
5.654SerLeu: 5.654 ± 1.32
1.06SerMet: 1.06 ± 0.312
2.827SerAsn: 2.827 ± 0.657
2.473SerPro: 2.473 ± 0.676
4.594SerGln: 4.594 ± 0.578
5.3SerArg: 5.3 ± 1.599
3.18SerSer: 3.18 ± 0.117
5.3SerThr: 5.3 ± 0.546
3.18SerVal: 3.18 ± 0.117
1.413SerTrp: 1.413 ± 0.592
1.767SerTyr: 1.767 ± 0.709
0.0SerXaa: 0.0 ± 0.0
Thr
7.42ThrAla: 7.42 ± 1.502
0.353ThrCys: 0.353 ± 0.247
6.007ThrAsp: 6.007 ± 1.067
3.18ThrGlu: 3.18 ± 0.117
2.473ThrPhe: 2.473 ± 0.149
5.3ThrGly: 5.3 ± 0.019
2.12ThrHis: 2.12 ± 0.429
2.473ThrIle: 2.473 ± 0.377
1.413ThrLys: 1.413 ± 0.065
6.36ThrLeu: 6.36 ± 1.874
0.707ThrMet: 0.707 ± 0.033
2.473ThrAsn: 2.473 ± 0.676
4.947ThrPro: 4.947 ± 0.826
3.18ThrGln: 3.18 ± 0.41
5.654ThrArg: 5.654 ± 1.314
2.827ThrSer: 2.827 ± 0.396
2.827ThrThr: 2.827 ± 1.184
3.18ThrVal: 3.18 ± 0.117
1.413ThrTrp: 1.413 ± 0.592
2.12ThrTyr: 2.12 ± 1.678
0.353ThrXaa: 0.353 ± 0.247
Val
4.24ValAla: 4.24 ± 0.195
0.353ValCys: 0.353 ± 0.28
2.473ValAsp: 2.473 ± 0.377
1.06ValGlu: 1.06 ± 0.312
2.12ValPhe: 2.12 ± 0.098
3.534ValGly: 3.534 ± 1.216
1.413ValHis: 1.413 ± 0.462
3.534ValIle: 3.534 ± 0.163
4.947ValLys: 4.947 ± 2.862
4.594ValLeu: 4.594 ± 0.052
1.413ValMet: 1.413 ± 1.119
3.534ValAsn: 3.534 ± 0.163
3.18ValPro: 3.18 ± 1.17
2.473ValGln: 2.473 ± 0.676
3.18ValArg: 3.18 ± 0.117
5.3ValSer: 5.3 ± 0.546
3.18ValThr: 3.18 ± 1.17
1.413ValVal: 1.413 ± 0.988
0.707ValTrp: 0.707 ± 0.494
1.767ValTyr: 1.767 ± 0.182
0.353ValXaa: 0.353 ± 0.247
Trp
1.06TrpAla: 1.06 ± 0.215
0.0TrpCys: 0.0 ± 0.0
1.767TrpAsp: 1.767 ± 0.182
1.413TrpGlu: 1.413 ± 0.592
1.06TrpPhe: 1.06 ± 0.312
0.707TrpGly: 0.707 ± 0.033
0.0TrpHis: 0.0 ± 0.0
1.413TrpIle: 1.413 ± 0.462
0.0TrpLys: 0.0 ± 0.0
1.413TrpLeu: 1.413 ± 0.592
0.353TrpMet: 0.353 ± 0.247
0.707TrpAsn: 0.707 ± 0.033
1.06TrpPro: 1.06 ± 0.741
0.707TrpGln: 0.707 ± 0.033
1.06TrpArg: 1.06 ± 0.215
2.827TrpSer: 2.827 ± 0.923
0.353TrpThr: 0.353 ± 0.28
0.353TrpVal: 0.353 ± 0.28
0.0TrpTrp: 0.0 ± 0.0
0.707TrpTyr: 0.707 ± 0.559
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.887TyrAla: 3.887 ± 0.969
1.06TyrCys: 1.06 ± 0.312
2.473TyrAsp: 2.473 ± 1.431
0.707TyrGlu: 0.707 ± 0.033
1.767TyrPhe: 1.767 ± 0.709
2.473TyrGly: 2.473 ± 0.149
0.0TyrHis: 0.0 ± 0.0
2.12TyrIle: 2.12 ± 0.625
1.413TyrLys: 1.413 ± 0.065
3.534TyrLeu: 3.534 ± 0.69
1.06TyrMet: 1.06 ± 0.215
2.12TyrAsn: 2.12 ± 0.098
1.767TyrPro: 1.767 ± 0.872
1.06TyrGln: 1.06 ± 0.741
2.12TyrArg: 2.12 ± 0.429
1.767TyrSer: 1.767 ± 0.182
3.18TyrThr: 3.18 ± 1.464
1.06TyrVal: 1.06 ± 0.312
0.707TyrTrp: 0.707 ± 0.033
0.707TyrTyr: 0.707 ± 0.494
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.353XaaGly: 0.353 ± 0.247
0.0XaaHis: 0.0 ± 0.0
0.707XaaIle: 0.707 ± 0.494
0.353XaaLys: 0.353 ± 0.28
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.353XaaThr: 0.353 ± 0.28
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2831 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski