Amino acid dipepetide frequency for Wuhan insect virus 19

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.35AlaAla: 1.35 ± 0.673
0.578AlaCys: 0.578 ± 0.288
1.35AlaAsp: 1.35 ± 0.277
1.928AlaGlu: 1.928 ± 0.675
2.121AlaPhe: 2.121 ± 0.464
1.157AlaGly: 1.157 ± 0.206
0.386AlaHis: 0.386 ± 0.192
3.471AlaIle: 3.471 ± 0.639
2.314AlaLys: 2.314 ± 0.724
5.013AlaLeu: 5.013 ± 0.596
0.193AlaMet: 0.193 ± 0.096
2.7AlaAsn: 2.7 ± 1.117
0.578AlaPro: 0.578 ± 0.615
1.35AlaGln: 1.35 ± 0.673
2.121AlaArg: 2.121 ± 0.735
1.35AlaSer: 1.35 ± 0.673
1.928AlaThr: 1.928 ± 0.549
1.735AlaVal: 1.735 ± 0.417
0.386AlaTrp: 0.386 ± 0.192
1.928AlaTyr: 1.928 ± 0.961
0.0AlaXaa: 0.0 ± 0.0
Cys
0.386CysAla: 0.386 ± 0.192
0.578CysCys: 0.578 ± 0.288
0.386CysAsp: 0.386 ± 0.192
1.928CysGlu: 1.928 ± 0.538
0.771CysPhe: 0.771 ± 1.068
0.964CysGly: 0.964 ± 0.163
0.193CysHis: 0.193 ± 0.385
0.578CysIle: 0.578 ± 0.683
1.157CysLys: 1.157 ± 0.9
1.543CysLeu: 1.543 ± 0.359
0.578CysMet: 0.578 ± 0.224
1.35CysAsn: 1.35 ± 0.387
0.386CysPro: 0.386 ± 0.192
0.386CysGln: 0.386 ± 0.192
0.193CysArg: 0.193 ± 0.096
0.964CysSer: 0.964 ± 0.163
0.386CysThr: 0.386 ± 0.3
0.771CysVal: 0.771 ± 0.384
0.193CysTrp: 0.193 ± 0.096
0.771CysTyr: 0.771 ± 0.384
0.0CysXaa: 0.0 ± 0.0
Asp
1.735AspAla: 1.735 ± 0.448
0.771AspCys: 0.771 ± 0.384
1.928AspAsp: 1.928 ± 0.326
2.892AspGlu: 2.892 ± 0.579
3.471AspPhe: 3.471 ± 0.617
2.314AspGly: 2.314 ± 1.031
0.771AspHis: 0.771 ± 0.171
4.821AspIle: 4.821 ± 1.165
4.628AspLys: 4.628 ± 1.866
4.049AspLeu: 4.049 ± 0.769
1.928AspMet: 1.928 ± 0.538
3.278AspAsn: 3.278 ± 0.655
1.543AspPro: 1.543 ± 0.342
1.543AspGln: 1.543 ± 1.2
2.314AspArg: 2.314 ± 0.384
3.085AspSer: 3.085 ± 0.243
2.314AspThr: 2.314 ± 0.384
3.664AspVal: 3.664 ± 0.901
0.964AspTrp: 0.964 ± 0.66
4.242AspTyr: 4.242 ± 0.254
0.0AspXaa: 0.0 ± 0.0
Glu
2.7GluAla: 2.7 ± 0.913
0.771GluCys: 0.771 ± 0.384
4.435GluAsp: 4.435 ± 1.258
6.363GluGlu: 6.363 ± 0.769
5.592GluPhe: 5.592 ± 0.883
3.664GluGly: 3.664 ± 1.477
1.157GluHis: 1.157 ± 0.206
5.592GluIle: 5.592 ± 0.479
7.52GluLys: 7.52 ± 1.276
6.942GluLeu: 6.942 ± 0.612
1.35GluMet: 1.35 ± 0.311
5.978GluAsn: 5.978 ± 1.091
1.157GluPro: 1.157 ± 0.576
5.206GluGln: 5.206 ± 1.343
4.435GluArg: 4.435 ± 1.355
2.314GluSer: 2.314 ± 0.384
2.507GluThr: 2.507 ± 0.486
4.435GluVal: 4.435 ± 0.796
0.771GluTrp: 0.771 ± 0.171
1.928GluTyr: 1.928 ± 0.961
0.0GluXaa: 0.0 ± 0.0
Phe
1.35PheAla: 1.35 ± 0.559
0.578PheCys: 0.578 ± 0.683
2.507PheAsp: 2.507 ± 1.249
4.435PheGlu: 4.435 ± 0.312
2.7PhePhe: 2.7 ± 0.553
2.7PheGly: 2.7 ± 0.952
0.386PheHis: 0.386 ± 0.192
2.892PheIle: 2.892 ± 1.007
5.206PheLys: 5.206 ± 1.235
5.592PheLeu: 5.592 ± 1.889
1.543PheMet: 1.543 ± 0.342
4.049PheAsn: 4.049 ± 0.824
0.964PhePro: 0.964 ± 0.555
0.964PheGln: 0.964 ± 0.48
1.735PheArg: 1.735 ± 1.582
4.049PheSer: 4.049 ± 0.604
2.892PheThr: 2.892 ± 0.47
3.857PheVal: 3.857 ± 0.854
0.964PheTrp: 0.964 ± 0.983
2.314PheTyr: 2.314 ± 1.664
0.0PheXaa: 0.0 ± 0.0
Gly
1.735GlyAla: 1.735 ± 0.417
0.771GlyCys: 0.771 ± 0.384
2.7GlyAsp: 2.7 ± 0.257
3.278GlyGlu: 3.278 ± 0.806
2.892GlyPhe: 2.892 ± 0.724
2.121GlyGly: 2.121 ± 0.392
0.964GlyHis: 0.964 ± 0.48
3.085GlyIle: 3.085 ± 0.683
3.085GlyLys: 3.085 ± 1.285
4.242GlyLeu: 4.242 ± 2.114
0.771GlyMet: 0.771 ± 0.6
3.278GlyAsn: 3.278 ± 1.828
0.771GlyPro: 0.771 ± 0.384
1.543GlyGln: 1.543 ± 0.359
3.085GlyArg: 3.085 ± 2.481
3.085GlySer: 3.085 ± 0.82
3.664GlyThr: 3.664 ± 0.901
2.7GlyVal: 2.7 ± 1.64
0.386GlyTrp: 0.386 ± 0.192
2.892GlyTyr: 2.892 ± 0.634
0.0GlyXaa: 0.0 ± 0.0
His
0.386HisAla: 0.386 ± 0.192
0.193HisCys: 0.193 ± 0.096
1.157HisAsp: 1.157 ± 0.576
0.771HisGlu: 0.771 ± 0.6
0.771HisPhe: 0.771 ± 0.384
0.771HisGly: 0.771 ± 0.384
0.386HisHis: 0.386 ± 0.192
2.507HisIle: 2.507 ± 0.995
2.892HisLys: 2.892 ± 0.974
2.121HisLeu: 2.121 ± 0.358
0.0HisMet: 0.0 ± 0.0
1.157HisAsn: 1.157 ± 0.206
0.193HisPro: 0.193 ± 0.096
0.578HisGln: 0.578 ± 0.288
0.193HisArg: 0.193 ± 0.385
1.35HisSer: 1.35 ± 0.277
0.193HisThr: 0.193 ± 0.096
1.157HisVal: 1.157 ± 1.374
0.0HisTrp: 0.0 ± 0.0
0.771HisTyr: 0.771 ± 0.171
0.0HisXaa: 0.0 ± 0.0
Ile
4.242IleAla: 4.242 ± 2.114
0.578IleCys: 0.578 ± 0.288
4.049IleAsp: 4.049 ± 0.819
5.399IleGlu: 5.399 ± 1.721
3.085IlePhe: 3.085 ± 0.683
5.592IleGly: 5.592 ± 1.164
1.928IleHis: 1.928 ± 0.609
6.942IleIle: 6.942 ± 1.538
6.749IleLys: 6.749 ± 0.616
8.292IleLeu: 8.292 ± 0.725
3.664IleMet: 3.664 ± 1.297
5.592IleAsn: 5.592 ± 0.443
2.121IlePro: 2.121 ± 0.555
3.471IleGln: 3.471 ± 0.629
2.892IleArg: 2.892 ± 0.488
5.785IleSer: 5.785 ± 0.545
4.242IleThr: 4.242 ± 0.91
4.435IleVal: 4.435 ± 0.765
1.35IleTrp: 1.35 ± 0.277
4.821IleTyr: 4.821 ± 1.729
0.0IleXaa: 0.0 ± 0.0
Lys
1.928LysAla: 1.928 ± 0.326
1.157LysCys: 1.157 ± 0.206
5.206LysAsp: 5.206 ± 0.828
8.292LysGlu: 8.292 ± 2.034
4.242LysPhe: 4.242 ± 1.504
4.628LysGly: 4.628 ± 1.102
1.35LysHis: 1.35 ± 0.517
8.292LysIle: 8.292 ± 1.391
8.87LysLys: 8.87 ± 0.335
9.063LysLeu: 9.063 ± 1.782
2.892LysMet: 2.892 ± 0.245
7.52LysAsn: 7.52 ± 0.486
1.35LysPro: 1.35 ± 0.673
4.242LysGln: 4.242 ± 0.716
4.049LysArg: 4.049 ± 0.346
4.435LysSer: 4.435 ± 3.004
3.857LysThr: 3.857 ± 0.753
4.821LysVal: 4.821 ± 0.865
0.964LysTrp: 0.964 ± 0.48
4.628LysTyr: 4.628 ± 0.822
0.0LysXaa: 0.0 ± 0.0
Leu
2.507LeuAla: 2.507 ± 0.478
1.35LeuCys: 1.35 ± 1.282
4.242LeuAsp: 4.242 ± 0.716
6.942LeuGlu: 6.942 ± 1.462
3.857LeuPhe: 3.857 ± 0.44
3.471LeuGly: 3.471 ± 1.293
1.543LeuHis: 1.543 ± 0.584
6.942LeuIle: 6.942 ± 1.431
8.292LeuLys: 8.292 ± 1.437
6.749LeuLeu: 6.749 ± 1.139
4.049LeuMet: 4.049 ± 0.678
6.556LeuAsn: 6.556 ± 1.133
2.7LeuPro: 2.7 ± 0.952
3.471LeuGln: 3.471 ± 1.664
1.928LeuArg: 1.928 ± 0.538
5.399LeuSer: 5.399 ± 0.688
5.592LeuThr: 5.592 ± 1.186
5.013LeuVal: 5.013 ± 0.956
1.735LeuTrp: 1.735 ± 0.32
4.435LeuTyr: 4.435 ± 0.846
0.0LeuXaa: 0.0 ± 0.0
Met
0.771MetAla: 0.771 ± 0.578
0.193MetCys: 0.193 ± 0.096
0.964MetAsp: 0.964 ± 0.48
1.35MetGlu: 1.35 ± 0.387
0.771MetPhe: 0.771 ± 0.384
0.578MetGly: 0.578 ± 0.288
0.386MetHis: 0.386 ± 0.192
2.507MetIle: 2.507 ± 0.833
2.121MetLys: 2.121 ± 0.358
1.928MetLeu: 1.928 ± 0.948
0.964MetMet: 0.964 ± 0.48
1.735MetAsn: 1.735 ± 0.417
1.157MetPro: 1.157 ± 0.9
0.964MetGln: 0.964 ± 0.66
0.578MetArg: 0.578 ± 0.224
2.507MetSer: 2.507 ± 1.249
1.35MetThr: 1.35 ± 0.673
2.892MetVal: 2.892 ± 0.488
0.771MetTrp: 0.771 ± 0.578
2.121MetTyr: 2.121 ± 0.392
0.0MetXaa: 0.0 ± 0.0
Asn
2.7AsnAla: 2.7 ± 0.512
1.543AsnCys: 1.543 ± 0.744
2.892AsnAsp: 2.892 ± 0.231
4.435AsnGlu: 4.435 ± 0.765
3.857AsnPhe: 3.857 ± 0.073
4.435AsnGly: 4.435 ± 0.673
0.964AsnHis: 0.964 ± 0.163
7.327AsnIle: 7.327 ± 1.971
9.063AsnLys: 9.063 ± 0.615
6.363AsnLeu: 6.363 ± 1.667
0.964AsnMet: 0.964 ± 0.163
6.17AsnAsn: 6.17 ± 1.09
2.121AsnPro: 2.121 ± 1.1
3.857AsnGln: 3.857 ± 0.998
1.928AsnArg: 1.928 ± 0.675
4.435AsnSer: 4.435 ± 2.998
3.664AsnThr: 3.664 ± 0.804
4.049AsnVal: 4.049 ± 0.132
1.928AsnTrp: 1.928 ± 0.961
3.664AsnTyr: 3.664 ± 0.986
0.0AsnXaa: 0.0 ± 0.0
Pro
0.0ProAla: 0.0 ± 0.0
0.386ProCys: 0.386 ± 0.3
1.735ProAsp: 1.735 ± 0.624
1.928ProGlu: 1.928 ± 0.961
0.771ProPhe: 0.771 ± 0.384
0.964ProGly: 0.964 ± 0.48
0.193ProHis: 0.193 ± 0.096
3.471ProIle: 3.471 ± 0.617
2.507ProLys: 2.507 ± 0.875
2.121ProLeu: 2.121 ± 0.358
1.35ProMet: 1.35 ± 1.235
1.735ProAsn: 1.735 ± 0.448
0.578ProPro: 0.578 ± 0.224
1.543ProGln: 1.543 ± 1.813
0.771ProArg: 0.771 ± 0.578
1.543ProSer: 1.543 ± 0.728
1.157ProThr: 1.157 ± 0.549
1.735ProVal: 1.735 ± 0.32
0.386ProTrp: 0.386 ± 0.192
0.964ProTyr: 0.964 ± 0.555
0.0ProXaa: 0.0 ± 0.0
Gln
2.892GlnAla: 2.892 ± 0.231
0.578GlnCys: 0.578 ± 0.683
2.314GlnAsp: 2.314 ± 0.411
2.507GlnGlu: 2.507 ± 0.833
1.928GlnPhe: 1.928 ± 0.549
0.771GlnGly: 0.771 ± 0.578
1.157GlnHis: 1.157 ± 0.206
2.507GlnIle: 2.507 ± 1.107
3.664GlnLys: 3.664 ± 0.107
2.7GlnLeu: 2.7 ± 0.553
0.386GlnMet: 0.386 ± 0.3
4.242GlnAsn: 4.242 ± 0.784
1.928GlnPro: 1.928 ± 0.326
2.7GlnGln: 2.7 ± 1.345
2.121GlnArg: 2.121 ± 0.464
2.121GlnSer: 2.121 ± 1.1
2.314GlnThr: 2.314 ± 0.803
1.735GlnVal: 1.735 ± 0.448
0.964GlnTrp: 0.964 ± 0.48
1.35GlnTyr: 1.35 ± 0.517
0.0GlnXaa: 0.0 ± 0.0
Arg
1.35ArgAla: 1.35 ± 0.559
0.964ArgCys: 0.964 ± 0.48
1.928ArgAsp: 1.928 ± 0.549
4.628ArgGlu: 4.628 ± 0.799
2.314ArgPhe: 2.314 ± 0.411
2.314ArgGly: 2.314 ± 1.959
0.578ArgHis: 0.578 ± 0.288
3.857ArgIle: 3.857 ± 0.073
2.892ArgLys: 2.892 ± 0.915
3.471ArgLeu: 3.471 ± 0.19
0.386ArgMet: 0.386 ± 0.192
2.892ArgAsn: 2.892 ± 1.032
0.964ArgPro: 0.964 ± 1.277
1.928ArgGln: 1.928 ± 0.675
1.735ArgArg: 1.735 ± 1.18
4.049ArgSer: 4.049 ± 5.165
1.735ArgThr: 1.735 ± 0.448
2.507ArgVal: 2.507 ± 0.312
0.193ArgTrp: 0.193 ± 0.096
0.964ArgTyr: 0.964 ± 1.452
0.0ArgXaa: 0.0 ± 0.0
Ser
1.35SerAla: 1.35 ± 0.559
0.771SerCys: 0.771 ± 0.6
3.085SerAsp: 3.085 ± 0.719
6.17SerGlu: 6.17 ± 0.441
2.892SerPhe: 2.892 ± 0.634
4.049SerGly: 4.049 ± 0.346
1.928SerHis: 1.928 ± 1.124
3.278SerIle: 3.278 ± 0.806
6.363SerLys: 6.363 ± 2.165
5.013SerLeu: 5.013 ± 1.064
1.928SerMet: 1.928 ± 0.441
4.242SerAsn: 4.242 ± 3.062
1.735SerPro: 1.735 ± 0.638
2.121SerGln: 2.121 ± 0.392
3.857SerArg: 3.857 ± 5.22
3.471SerSer: 3.471 ± 0.629
2.121SerThr: 2.121 ± 0.631
3.471SerVal: 3.471 ± 0.895
0.578SerTrp: 0.578 ± 0.224
3.471SerTyr: 3.471 ± 0.629
0.0SerXaa: 0.0 ± 0.0
Thr
1.543ThrAla: 1.543 ± 0.359
0.386ThrCys: 0.386 ± 0.3
2.121ThrAsp: 2.121 ± 0.735
4.242ThrGlu: 4.242 ± 1.675
2.7ThrPhe: 2.7 ± 1.943
1.928ThrGly: 1.928 ± 0.609
0.771ThrHis: 0.771 ± 0.171
6.17ThrIle: 6.17 ± 2.098
3.085ThrLys: 3.085 ± 0.517
4.242ThrLeu: 4.242 ± 0.805
0.964ThrMet: 0.964 ± 0.48
3.664ThrAsn: 3.664 ± 1.297
1.157ThrPro: 1.157 ± 0.206
1.157ThrGln: 1.157 ± 0.206
1.928ThrArg: 1.928 ± 0.393
3.857ThrSer: 3.857 ± 0.988
2.121ThrThr: 2.121 ± 1.843
2.892ThrVal: 2.892 ± 0.579
0.964ThrTrp: 0.964 ± 0.48
2.7ThrTyr: 2.7 ± 1.011
0.0ThrXaa: 0.0 ± 0.0
Val
2.121ValAla: 2.121 ± 0.631
1.157ValCys: 1.157 ± 0.206
4.242ValAsp: 4.242 ± 1.262
3.278ValGlu: 3.278 ± 0.561
2.892ValPhe: 2.892 ± 0.47
1.928ValGly: 1.928 ± 0.326
1.35ValHis: 1.35 ± 0.517
6.17ValIle: 6.17 ± 1.287
5.978ValLys: 5.978 ± 1.562
3.278ValLeu: 3.278 ± 0.996
0.964ValMet: 0.964 ± 0.163
4.821ValAsn: 4.821 ± 0.865
2.7ValPro: 2.7 ± 0.257
0.964ValGln: 0.964 ± 0.521
3.085ValArg: 3.085 ± 0.653
4.049ValSer: 4.049 ± 0.83
2.121ValThr: 2.121 ± 1.057
3.664ValVal: 3.664 ± 0.986
0.964ValTrp: 0.964 ± 0.48
2.507ValTyr: 2.507 ± 0.875
0.0ValXaa: 0.0 ± 0.0
Trp
0.964TrpAla: 0.964 ± 0.163
0.0TrpCys: 0.0 ± 0.0
1.735TrpAsp: 1.735 ± 0.638
1.735TrpGlu: 1.735 ± 0.865
0.386TrpPhe: 0.386 ± 0.192
0.771TrpGly: 0.771 ± 0.171
0.386TrpHis: 0.386 ± 0.664
1.35TrpIle: 1.35 ± 0.277
0.771TrpLys: 0.771 ± 0.171
1.35TrpLeu: 1.35 ± 0.82
0.386TrpMet: 0.386 ± 0.192
0.964TrpAsn: 0.964 ± 0.163
0.386TrpPro: 0.386 ± 0.192
0.964TrpGln: 0.964 ± 0.163
0.964TrpArg: 0.964 ± 0.48
0.964TrpSer: 0.964 ± 0.48
0.193TrpThr: 0.193 ± 0.096
0.771TrpVal: 0.771 ± 0.384
0.0TrpTrp: 0.0 ± 0.0
0.386TrpTyr: 0.386 ± 0.3
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.928TyrAla: 1.928 ± 1.32
1.157TyrCys: 1.157 ± 0.576
3.278TyrAsp: 3.278 ± 2.134
2.314TyrGlu: 2.314 ± 0.411
3.664TyrPhe: 3.664 ± 0.534
1.928TyrGly: 1.928 ± 0.675
0.771TyrHis: 0.771 ± 0.384
3.471TyrIle: 3.471 ± 0.617
4.628TyrLys: 4.628 ± 0.642
2.7TyrLeu: 2.7 ± 0.257
1.157TyrMet: 1.157 ± 0.576
4.435TyrAsn: 4.435 ± 1.355
1.35TyrPro: 1.35 ± 0.387
1.928TyrGln: 1.928 ± 0.538
1.735TyrArg: 1.735 ± 1.044
3.278TyrSer: 3.278 ± 0.655
4.242TyrThr: 4.242 ± 0.728
1.928TyrVal: 1.928 ± 0.326
0.964TyrTrp: 0.964 ± 0.983
2.121TyrTyr: 2.121 ± 0.555
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (5187 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski