Amino acid dipepetide frequency for Hubei tombus-like virus 23

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.812AlaAla: 4.812 ± 0.89
0.0AlaCys: 0.0 ± 0.0
2.887AlaAsp: 2.887 ± 2.008
3.85AlaGlu: 3.85 ± 1.266
3.85AlaPhe: 3.85 ± 1.559
0.962AlaGly: 0.962 ± 0.669
0.0AlaHis: 0.0 ± 0.0
4.812AlaIle: 4.812 ± 3.714
5.775AlaLys: 5.775 ± 1.633
1.925AlaLeu: 1.925 ± 0.073
5.775AlaMet: 5.775 ± 1.192
3.85AlaAsn: 3.85 ± 2.678
1.925AlaPro: 1.925 ± 1.339
1.925AlaGln: 1.925 ± 0.073
3.85AlaArg: 3.85 ± 1.559
5.775AlaSer: 5.775 ± 0.22
5.775AlaThr: 5.775 ± 1.192
0.962AlaVal: 0.962 ± 0.669
0.962AlaTrp: 0.962 ± 0.743
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.962CysAla: 0.962 ± 0.669
0.0CysCys: 0.0 ± 0.0
0.962CysAsp: 0.962 ± 0.743
1.925CysGlu: 1.925 ± 1.486
0.0CysPhe: 0.0 ± 0.0
0.962CysGly: 0.962 ± 0.743
0.0CysHis: 0.0 ± 0.0
1.925CysIle: 1.925 ± 0.073
0.962CysLys: 0.962 ± 0.669
1.925CysLeu: 1.925 ± 0.073
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
3.85CysGln: 3.85 ± 1.559
0.962CysArg: 0.962 ± 0.743
0.962CysSer: 0.962 ± 0.743
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.962CysTyr: 0.962 ± 0.743
0.0CysXaa: 0.0 ± 0.0
Asp
2.887AspAla: 2.887 ± 0.596
0.962AspCys: 0.962 ± 0.743
3.85AspAsp: 3.85 ± 0.147
2.887AspGlu: 2.887 ± 0.816
1.925AspPhe: 1.925 ± 0.073
3.85AspGly: 3.85 ± 0.147
0.962AspHis: 0.962 ± 0.743
2.887AspIle: 2.887 ± 0.596
2.887AspLys: 2.887 ± 0.596
1.925AspLeu: 1.925 ± 1.339
0.962AspMet: 0.962 ± 0.669
1.925AspAsn: 1.925 ± 0.073
2.887AspPro: 2.887 ± 0.816
0.962AspGln: 0.962 ± 0.669
1.925AspArg: 1.925 ± 1.486
5.775AspSer: 5.775 ± 0.22
1.925AspThr: 1.925 ± 1.339
2.887AspVal: 2.887 ± 0.596
0.0AspTrp: 0.0 ± 0.0
1.925AspTyr: 1.925 ± 1.486
0.0AspXaa: 0.0 ± 0.0
Glu
2.887GluAla: 2.887 ± 0.816
0.962GluCys: 0.962 ± 0.669
0.962GluAsp: 0.962 ± 0.669
7.7GluGlu: 7.7 ± 0.294
1.925GluPhe: 1.925 ± 1.486
1.925GluGly: 1.925 ± 0.073
0.962GluHis: 0.962 ± 0.669
6.737GluIle: 6.737 ± 2.375
4.812GluLys: 4.812 ± 0.89
7.7GluLeu: 7.7 ± 1.706
1.925GluMet: 1.925 ± 0.073
2.887GluAsn: 2.887 ± 0.816
3.85GluPro: 3.85 ± 0.147
1.925GluGln: 1.925 ± 0.073
7.7GluArg: 7.7 ± 2.531
9.625GluSer: 9.625 ± 0.367
3.85GluThr: 3.85 ± 1.266
3.85GluVal: 3.85 ± 0.147
0.0GluTrp: 0.0 ± 0.0
3.85GluTyr: 3.85 ± 2.972
0.0GluXaa: 0.0 ± 0.0
Phe
1.925PheAla: 1.925 ± 1.486
0.962PheCys: 0.962 ± 0.743
0.962PheAsp: 0.962 ± 0.743
2.887PheGlu: 2.887 ± 0.816
0.962PhePhe: 0.962 ± 0.669
2.887PheGly: 2.887 ± 0.596
2.887PheHis: 2.887 ± 0.816
0.962PheIle: 0.962 ± 0.743
2.887PheLys: 2.887 ± 0.596
0.962PheLeu: 0.962 ± 0.743
0.0PheMet: 0.0 ± 0.0
1.925PheAsn: 1.925 ± 0.073
0.962PhePro: 0.962 ± 0.669
1.925PheGln: 1.925 ± 1.339
0.0PheArg: 0.0 ± 0.0
0.962PheSer: 0.962 ± 0.743
1.925PheThr: 1.925 ± 1.339
0.0PheVal: 0.0 ± 0.0
0.0PheTrp: 0.0 ± 0.0
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
0.962GlyAla: 0.962 ± 0.743
1.925GlyCys: 1.925 ± 0.073
3.85GlyAsp: 3.85 ± 1.559
5.775GlyGlu: 5.775 ± 0.22
2.887GlyPhe: 2.887 ± 0.596
2.887GlyGly: 2.887 ± 0.596
1.925GlyHis: 1.925 ± 0.073
2.887GlyIle: 2.887 ± 2.229
5.775GlyLys: 5.775 ± 2.605
2.887GlyLeu: 2.887 ± 0.596
2.887GlyMet: 2.887 ± 0.397
0.962GlyAsn: 0.962 ± 0.669
0.0GlyPro: 0.0 ± 0.0
0.0GlyGln: 0.0 ± 0.0
0.962GlyArg: 0.962 ± 0.669
1.925GlySer: 1.925 ± 0.073
5.775GlyThr: 5.775 ± 1.192
2.887GlyVal: 2.887 ± 0.816
0.0GlyTrp: 0.0 ± 0.0
1.925GlyTyr: 1.925 ± 1.486
0.0GlyXaa: 0.0 ± 0.0
His
2.887HisAla: 2.887 ± 2.008
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
0.0HisGly: 0.0 ± 0.0
0.962HisHis: 0.962 ± 0.669
0.0HisIle: 0.0 ± 0.0
2.887HisLys: 2.887 ± 0.816
3.85HisLeu: 3.85 ± 1.266
2.887HisMet: 2.887 ± 0.596
0.0HisAsn: 0.0 ± 0.0
0.962HisPro: 0.962 ± 0.743
1.925HisGln: 1.925 ± 0.073
0.0HisArg: 0.0 ± 0.0
1.925HisSer: 1.925 ± 0.073
0.962HisThr: 0.962 ± 0.743
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
0.962HisTyr: 0.962 ± 0.743
0.0HisXaa: 0.0 ± 0.0
Ile
7.7IleAla: 7.7 ± 0.294
0.962IleCys: 0.962 ± 0.743
1.925IleAsp: 1.925 ± 1.486
7.7IleGlu: 7.7 ± 4.531
0.0IlePhe: 0.0 ± 0.0
0.962IleGly: 0.962 ± 0.743
0.962IleHis: 0.962 ± 0.669
0.962IleIle: 0.962 ± 0.669
7.7IleLys: 7.7 ± 1.706
0.962IleLeu: 0.962 ± 0.743
0.962IleMet: 0.962 ± 0.743
3.85IleAsn: 3.85 ± 0.147
0.0IlePro: 0.0 ± 0.0
3.85IleGln: 3.85 ± 0.147
2.887IleArg: 2.887 ± 0.596
4.812IleSer: 4.812 ± 1.935
3.85IleThr: 3.85 ± 1.559
2.887IleVal: 2.887 ± 0.816
0.962IleTrp: 0.962 ± 0.743
1.925IleTyr: 1.925 ± 1.486
0.0IleXaa: 0.0 ± 0.0
Lys
8.662LysAla: 8.662 ± 3.201
0.962LysCys: 0.962 ± 0.743
4.812LysAsp: 4.812 ± 0.523
7.7LysGlu: 7.7 ± 2.531
1.925LysPhe: 1.925 ± 0.073
7.7LysGly: 7.7 ± 0.294
1.925LysHis: 1.925 ± 1.339
2.887LysIle: 2.887 ± 0.816
3.85LysLys: 3.85 ± 1.266
7.7LysLeu: 7.7 ± 1.119
2.887LysMet: 2.887 ± 0.417
3.85LysAsn: 3.85 ± 1.266
5.775LysPro: 5.775 ± 1.192
4.812LysGln: 4.812 ± 1.935
7.7LysArg: 7.7 ± 2.531
6.737LysSer: 6.737 ± 3.274
3.85LysThr: 3.85 ± 2.972
2.887LysVal: 2.887 ± 0.816
3.85LysTrp: 3.85 ± 1.559
3.85LysTyr: 3.85 ± 1.559
0.0LysXaa: 0.0 ± 0.0
Leu
0.962LeuAla: 0.962 ± 0.743
0.0LeuCys: 0.0 ± 0.0
3.85LeuAsp: 3.85 ± 1.559
1.925LeuGlu: 1.925 ± 1.486
0.962LeuPhe: 0.962 ± 0.669
4.812LeuGly: 4.812 ± 0.89
1.925LeuHis: 1.925 ± 0.073
6.737LeuIle: 6.737 ± 0.449
6.737LeuLys: 6.737 ± 3.274
5.775LeuLeu: 5.775 ± 0.22
0.0LeuMet: 0.0 ± 0.0
8.662LeuAsn: 8.662 ± 1.037
5.775LeuPro: 5.775 ± 0.22
4.812LeuGln: 4.812 ± 0.523
5.775LeuArg: 5.775 ± 2.605
3.85LeuSer: 3.85 ± 2.678
3.85LeuThr: 3.85 ± 1.266
1.925LeuVal: 1.925 ± 1.486
0.962LeuTrp: 0.962 ± 0.743
0.962LeuTyr: 0.962 ± 0.743
0.0LeuXaa: 0.0 ± 0.0
Met
0.962MetAla: 0.962 ± 0.669
0.0MetCys: 0.0 ± 0.0
2.887MetAsp: 2.887 ± 0.816
2.887MetGlu: 2.887 ± 0.596
0.0MetPhe: 0.0 ± 0.0
0.962MetGly: 0.962 ± 0.743
0.0MetHis: 0.0 ± 0.0
5.775MetIle: 5.775 ± 1.633
3.85MetLys: 3.85 ± 1.559
0.962MetLeu: 0.962 ± 0.669
2.887MetMet: 2.887 ± 2.008
2.887MetAsn: 2.887 ± 2.008
0.0MetPro: 0.0 ± 0.0
0.962MetGln: 0.962 ± 0.669
1.925MetArg: 1.925 ± 1.339
1.925MetSer: 1.925 ± 0.073
1.925MetThr: 1.925 ± 0.073
2.887MetVal: 2.887 ± 0.596
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
0.962AsnAla: 0.962 ± 0.669
0.0AsnCys: 0.0 ± 0.0
2.887AsnAsp: 2.887 ± 0.596
3.85AsnGlu: 3.85 ± 0.147
1.925AsnPhe: 1.925 ± 1.339
3.85AsnGly: 3.85 ± 1.559
0.962AsnHis: 0.962 ± 0.669
3.85AsnIle: 3.85 ± 1.559
6.737AsnLys: 6.737 ± 1.862
2.887AsnLeu: 2.887 ± 0.596
0.0AsnMet: 0.0 ± 0.0
2.887AsnAsn: 2.887 ± 0.596
2.887AsnPro: 2.887 ± 0.596
5.775AsnGln: 5.775 ± 1.192
0.962AsnArg: 0.962 ± 0.669
4.812AsnSer: 4.812 ± 3.347
2.887AsnThr: 2.887 ± 0.816
4.812AsnVal: 4.812 ± 0.523
0.962AsnTrp: 0.962 ± 0.743
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
0.962ProAla: 0.962 ± 0.743
1.925ProCys: 1.925 ± 1.486
0.0ProAsp: 0.0 ± 0.0
1.925ProGlu: 1.925 ± 0.073
0.962ProPhe: 0.962 ± 0.743
1.925ProGly: 1.925 ± 0.073
0.0ProHis: 0.0 ± 0.0
2.887ProIle: 2.887 ± 0.816
3.85ProLys: 3.85 ± 0.147
2.887ProLeu: 2.887 ± 0.596
1.925ProMet: 1.925 ± 0.073
1.925ProAsn: 1.925 ± 0.073
1.925ProPro: 1.925 ± 1.486
0.962ProGln: 0.962 ± 0.669
0.962ProArg: 0.962 ± 0.743
3.85ProSer: 3.85 ± 0.147
3.85ProThr: 3.85 ± 0.147
5.775ProVal: 5.775 ± 0.22
0.962ProTrp: 0.962 ± 0.743
0.962ProTyr: 0.962 ± 0.743
0.0ProXaa: 0.0 ± 0.0
Gln
1.925GlnAla: 1.925 ± 0.073
1.925GlnCys: 1.925 ± 1.339
1.925GlnAsp: 1.925 ± 1.339
4.812GlnGlu: 4.812 ± 0.523
0.962GlnPhe: 0.962 ± 0.743
0.962GlnGly: 0.962 ± 0.669
2.887GlnHis: 2.887 ± 0.816
0.962GlnIle: 0.962 ± 0.743
3.85GlnLys: 3.85 ± 2.678
4.812GlnLeu: 4.812 ± 2.302
0.0GlnMet: 0.0 ± 0.0
1.925GlnAsn: 1.925 ± 1.339
2.887GlnPro: 2.887 ± 2.229
3.85GlnGln: 3.85 ± 0.147
4.812GlnArg: 4.812 ± 1.935
9.625GlnSer: 9.625 ± 3.87
5.775GlnThr: 5.775 ± 1.192
2.887GlnVal: 2.887 ± 0.596
0.0GlnTrp: 0.0 ± 0.0
1.925GlnTyr: 1.925 ± 0.073
0.0GlnXaa: 0.0 ± 0.0
Arg
2.887ArgAla: 2.887 ± 0.596
0.962ArgCys: 0.962 ± 0.743
2.887ArgAsp: 2.887 ± 0.596
3.85ArgGlu: 3.85 ± 0.147
2.887ArgPhe: 2.887 ± 2.008
1.925ArgGly: 1.925 ± 1.339
2.887ArgHis: 2.887 ± 0.816
0.962ArgIle: 0.962 ± 0.669
7.7ArgLys: 7.7 ± 0.294
5.775ArgLeu: 5.775 ± 1.192
4.812ArgMet: 4.812 ± 0.89
6.737ArgAsn: 6.737 ± 3.274
0.962ArgPro: 0.962 ± 0.743
4.812ArgGln: 4.812 ± 3.347
4.812ArgArg: 4.812 ± 0.523
1.925ArgSer: 1.925 ± 0.073
4.812ArgThr: 4.812 ± 0.523
1.925ArgVal: 1.925 ± 1.486
0.0ArgTrp: 0.0 ± 0.0
1.925ArgTyr: 1.925 ± 1.486
0.0ArgXaa: 0.0 ± 0.0
Ser
3.85SerAla: 3.85 ± 0.147
1.925SerCys: 1.925 ± 1.486
1.925SerAsp: 1.925 ± 1.339
7.7SerGlu: 7.7 ± 2.531
1.925SerPhe: 1.925 ± 0.073
6.737SerGly: 6.737 ± 3.274
0.0SerHis: 0.0 ± 0.0
2.887SerIle: 2.887 ± 0.596
10.587SerLys: 10.587 ± 3.127
8.662SerLeu: 8.662 ± 1.788
0.962SerMet: 0.962 ± 0.669
1.925SerAsn: 1.925 ± 0.073
1.925SerPro: 1.925 ± 1.486
1.925SerGln: 1.925 ± 0.073
5.775SerArg: 5.775 ± 1.192
5.775SerSer: 5.775 ± 2.605
7.7SerThr: 7.7 ± 2.531
0.962SerVal: 0.962 ± 0.743
2.887SerTrp: 2.887 ± 0.816
4.812SerTyr: 4.812 ± 0.89
0.0SerXaa: 0.0 ± 0.0
Thr
6.737ThrAla: 6.737 ± 0.449
0.962ThrCys: 0.962 ± 0.743
4.812ThrAsp: 4.812 ± 0.89
2.887ThrGlu: 2.887 ± 0.596
0.962ThrPhe: 0.962 ± 0.743
2.887ThrGly: 2.887 ± 0.816
0.962ThrHis: 0.962 ± 0.669
3.85ThrIle: 3.85 ± 0.147
7.7ThrLys: 7.7 ± 2.531
1.925ThrLeu: 1.925 ± 0.073
2.887ThrMet: 2.887 ± 0.596
2.887ThrAsn: 2.887 ± 0.596
1.925ThrPro: 1.925 ± 0.073
5.775ThrGln: 5.775 ± 1.192
5.775ThrArg: 5.775 ± 1.192
3.85ThrSer: 3.85 ± 1.266
3.85ThrThr: 3.85 ± 1.266
0.962ThrVal: 0.962 ± 0.743
0.962ThrTrp: 0.962 ± 0.669
2.887ThrTyr: 2.887 ± 0.816
0.0ThrXaa: 0.0 ± 0.0
Val
2.887ValAla: 2.887 ± 0.816
0.0ValCys: 0.0 ± 0.0
2.887ValAsp: 2.887 ± 0.596
2.887ValGlu: 2.887 ± 2.229
1.925ValPhe: 1.925 ± 1.486
0.962ValGly: 0.962 ± 0.669
0.0ValHis: 0.0 ± 0.0
0.962ValIle: 0.962 ± 0.669
3.85ValLys: 3.85 ± 0.147
3.85ValLeu: 3.85 ± 0.147
0.962ValMet: 0.962 ± 0.743
3.85ValAsn: 3.85 ± 1.559
1.925ValPro: 1.925 ± 0.073
3.85ValGln: 3.85 ± 1.266
1.925ValArg: 1.925 ± 0.073
3.85ValSer: 3.85 ± 0.147
1.925ValThr: 1.925 ± 0.073
1.925ValVal: 1.925 ± 0.073
0.0ValTrp: 0.0 ± 0.0
0.962ValTyr: 0.962 ± 0.743
0.0ValXaa: 0.0 ± 0.0
Trp
1.925TrpAla: 1.925 ± 0.073
0.0TrpCys: 0.0 ± 0.0
0.962TrpAsp: 0.962 ± 0.743
1.925TrpGlu: 1.925 ± 1.486
0.0TrpPhe: 0.0 ± 0.0
0.962TrpGly: 0.962 ± 0.743
0.0TrpHis: 0.0 ± 0.0
0.962TrpIle: 0.962 ± 0.743
0.0TrpLys: 0.0 ± 0.0
0.962TrpLeu: 0.962 ± 0.743
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.962TrpPro: 0.962 ± 0.743
0.962TrpGln: 0.962 ± 0.669
1.925TrpArg: 1.925 ± 0.073
0.962TrpSer: 0.962 ± 0.743
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.962TrpTyr: 0.962 ± 0.743
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.925TyrAla: 1.925 ± 1.486
1.925TyrCys: 1.925 ± 0.073
0.962TyrAsp: 0.962 ± 0.669
0.962TyrGlu: 0.962 ± 0.743
0.0TyrPhe: 0.0 ± 0.0
1.925TyrGly: 1.925 ± 1.486
0.0TyrHis: 0.0 ± 0.0
1.925TyrIle: 1.925 ± 0.073
1.925TyrLys: 1.925 ± 0.073
1.925TyrLeu: 1.925 ± 0.073
0.0TyrMet: 0.0 ± 0.0
0.962TyrAsn: 0.962 ± 0.743
2.887TyrPro: 2.887 ± 2.229
3.85TyrGln: 3.85 ± 2.972
4.812TyrArg: 4.812 ± 3.714
1.925TyrSer: 1.925 ± 1.486
0.962TyrThr: 0.962 ± 0.743
0.962TyrVal: 0.962 ± 0.743
0.962TyrTrp: 0.962 ± 0.743
1.925TyrTyr: 1.925 ± 1.486
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1040 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski