Amino acid dipepetide frequency for Gill-associated virus (isolate Giant tiger prawn/Australia) (GAV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.889AlaAla: 3.889 ± 0.701
1.191AlaCys: 1.191 ± 0.21
4.604AlaAsp: 4.604 ± 0.703
1.746AlaGlu: 1.746 ± 0.317
3.413AlaPhe: 3.413 ± 0.687
1.429AlaGly: 1.429 ± 0.892
2.857AlaHis: 2.857 ± 0.474
3.889AlaIle: 3.889 ± 0.38
2.778AlaLys: 2.778 ± 0.72
6.905AlaLeu: 6.905 ± 0.486
0.397AlaMet: 0.397 ± 0.245
3.413AlaAsn: 3.413 ± 0.491
2.222AlaPro: 2.222 ± 1.018
3.572AlaGln: 3.572 ± 0.536
3.095AlaArg: 3.095 ± 0.544
4.286AlaSer: 4.286 ± 0.425
3.81AlaThr: 3.81 ± 0.509
3.73AlaVal: 3.73 ± 0.407
0.317AlaTrp: 0.317 ± 0.211
4.127AlaTyr: 4.127 ± 0.276
0.0AlaXaa: 0.0 ± 0.0
Cys
1.905CysAla: 1.905 ± 0.29
0.556CysCys: 0.556 ± 0.177
1.27CysAsp: 1.27 ± 0.671
1.032CysGlu: 1.032 ± 0.179
1.349CysPhe: 1.349 ± 0.185
2.54CysGly: 2.54 ± 0.353
1.349CysHis: 1.349 ± 0.248
1.667CysIle: 1.667 ± 0.345
1.746CysLys: 1.746 ± 0.306
1.984CysLeu: 1.984 ± 0.337
0.714CysMet: 0.714 ± 0.086
1.826CysAsn: 1.826 ± 0.668
1.191CysPro: 1.191 ± 0.364
0.317CysGln: 0.317 ± 0.111
0.397CysArg: 0.397 ± 0.109
2.54CysSer: 2.54 ± 0.53
2.064CysThr: 2.064 ± 0.286
0.794CysVal: 0.794 ± 0.125
0.238CysTrp: 0.238 ± 0.09
1.826CysTyr: 1.826 ± 0.29
0.0CysXaa: 0.0 ± 0.0
Asp
2.937AspAla: 2.937 ± 0.364
1.746AspCys: 1.746 ± 0.214
2.54AspAsp: 2.54 ± 0.308
1.905AspGlu: 1.905 ± 0.244
3.413AspPhe: 3.413 ± 0.371
3.095AspGly: 3.095 ± 0.223
1.826AspHis: 1.826 ± 0.417
5.477AspIle: 5.477 ± 0.882
2.857AspLys: 2.857 ± 0.869
3.81AspLeu: 3.81 ± 0.572
0.873AspMet: 0.873 ± 0.133
2.461AspAsn: 2.461 ± 0.475
2.778AspPro: 2.778 ± 0.355
1.587AspGln: 1.587 ± 0.252
1.587AspArg: 1.587 ± 0.746
3.572AspSer: 3.572 ± 0.713
5.397AspThr: 5.397 ± 0.604
1.905AspVal: 1.905 ± 0.334
0.476AspTrp: 0.476 ± 0.985
3.016AspTyr: 3.016 ± 0.73
0.0AspXaa: 0.0 ± 0.0
Glu
2.778GluAla: 2.778 ± 0.642
1.349GluCys: 1.349 ± 0.158
2.461GluAsp: 2.461 ± 0.674
2.54GluGlu: 2.54 ± 0.471
1.746GluPhe: 1.746 ± 0.538
1.349GluGly: 1.349 ± 0.533
1.826GluHis: 1.826 ± 0.294
2.937GluIle: 2.937 ± 0.314
1.111GluLys: 1.111 ± 0.221
3.095GluLeu: 3.095 ± 0.722
0.317GluMet: 0.317 ± 0.111
1.191GluAsn: 1.191 ± 0.375
1.826GluPro: 1.826 ± 0.208
1.667GluGln: 1.667 ± 0.311
1.27GluArg: 1.27 ± 0.274
2.381GluSer: 2.381 ± 0.273
3.73GluThr: 3.73 ± 0.736
2.302GluVal: 2.302 ± 0.392
0.714GluTrp: 0.714 ± 0.204
2.381GluTyr: 2.381 ± 0.252
0.0GluXaa: 0.0 ± 0.0
Phe
3.889PheAla: 3.889 ± 0.968
1.191PheCys: 1.191 ± 0.218
2.699PheAsp: 2.699 ± 0.521
1.826PheGlu: 1.826 ± 0.294
1.984PhePhe: 1.984 ± 0.238
1.111PheGly: 1.111 ± 0.585
0.952PheHis: 0.952 ± 0.187
4.842PheIle: 4.842 ± 0.569
2.699PheLys: 2.699 ± 0.422
5.08PheLeu: 5.08 ± 1.44
0.873PheMet: 0.873 ± 0.143
2.937PheAsn: 2.937 ± 0.443
1.826PhePro: 1.826 ± 0.381
1.032PheGln: 1.032 ± 0.309
2.302PheArg: 2.302 ± 0.312
3.651PheSer: 3.651 ± 0.868
4.048PheThr: 4.048 ± 0.494
1.587PheVal: 1.587 ± 0.457
0.476PheTrp: 0.476 ± 0.055
2.54PheTyr: 2.54 ± 0.287
0.0PheXaa: 0.0 ± 0.0
Gly
3.413GlyAla: 3.413 ± 0.635
1.508GlyCys: 1.508 ± 0.422
2.937GlyAsp: 2.937 ± 0.722
1.349GlyGlu: 1.349 ± 0.248
1.587GlyPhe: 1.587 ± 0.334
2.222GlyGly: 2.222 ± 1.561
1.984GlyHis: 1.984 ± 0.227
5.0GlyIle: 5.0 ± 0.399
2.461GlyLys: 2.461 ± 1.116
3.413GlyLeu: 3.413 ± 0.99
0.556GlyMet: 0.556 ± 0.107
2.302GlyAsn: 2.302 ± 0.186
1.826GlyPro: 1.826 ± 0.835
1.27GlyGln: 1.27 ± 0.162
1.191GlyArg: 1.191 ± 0.263
3.095GlySer: 3.095 ± 0.835
3.572GlyThr: 3.572 ± 0.619
2.143GlyVal: 2.143 ± 0.722
0.317GlyTrp: 0.317 ± 0.237
2.937GlyTyr: 2.937 ± 0.581
0.0GlyXaa: 0.0 ± 0.0
His
2.222HisAla: 2.222 ± 0.203
1.27HisCys: 1.27 ± 0.245
1.905HisAsp: 1.905 ± 0.751
2.778HisGlu: 2.778 ± 0.636
1.746HisPhe: 1.746 ± 0.225
2.461HisGly: 2.461 ± 0.375
1.587HisHis: 1.587 ± 0.314
3.095HisIle: 3.095 ± 0.622
1.508HisLys: 1.508 ± 0.198
2.857HisLeu: 2.857 ± 0.601
0.397HisMet: 0.397 ± 0.109
2.937HisAsn: 2.937 ± 0.679
2.461HisPro: 2.461 ± 0.282
1.191HisGln: 1.191 ± 0.3
1.349HisArg: 1.349 ± 0.248
1.905HisSer: 1.905 ± 1.043
3.73HisThr: 3.73 ± 0.606
2.064HisVal: 2.064 ± 0.468
0.476HisTrp: 0.476 ± 0.137
1.27HisTyr: 1.27 ± 0.381
0.0HisXaa: 0.0 ± 0.0
Ile
4.762IleAla: 4.762 ± 0.546
1.984IleCys: 1.984 ± 0.384
4.524IleAsp: 4.524 ± 0.654
2.857IleGlu: 2.857 ± 0.804
4.683IlePhe: 4.683 ± 0.487
3.334IleGly: 3.334 ± 0.53
2.619IleHis: 2.619 ± 0.212
7.143IleIle: 7.143 ± 1.343
3.095IleLys: 3.095 ± 0.744
5.953IleLeu: 5.953 ± 0.527
1.667IleMet: 1.667 ± 0.715
5.556IleAsn: 5.556 ± 0.837
5.318IlePro: 5.318 ± 1.476
2.54IleGln: 2.54 ± 1.012
4.048IleArg: 4.048 ± 0.764
4.524IleSer: 4.524 ± 0.644
6.588IleThr: 6.588 ± 0.549
4.842IleVal: 4.842 ± 0.879
0.873IleTrp: 0.873 ± 0.254
4.207IleTyr: 4.207 ± 0.447
0.0IleXaa: 0.0 ± 0.0
Lys
1.508LysAla: 1.508 ± 0.576
0.476LysCys: 0.476 ± 0.055
1.905LysAsp: 1.905 ± 0.413
1.984LysGlu: 1.984 ± 0.234
2.619LysPhe: 2.619 ± 0.475
1.984LysGly: 1.984 ± 0.234
2.857LysHis: 2.857 ± 0.536
3.016LysIle: 3.016 ± 0.848
2.222LysLys: 2.222 ± 0.441
3.572LysLeu: 3.572 ± 0.46
0.952LysMet: 0.952 ± 0.219
2.064LysAsn: 2.064 ± 0.906
1.429LysPro: 1.429 ± 0.164
1.27LysGln: 1.27 ± 0.751
2.699LysArg: 2.699 ± 1.04
3.095LysSer: 3.095 ± 0.289
3.175LysThr: 3.175 ± 0.797
3.73LysVal: 3.73 ± 0.264
0.397LysTrp: 0.397 ± 0.109
3.175LysTyr: 3.175 ± 0.267
0.0LysXaa: 0.0 ± 0.0
Leu
5.397LeuAla: 5.397 ± 0.824
3.175LeuCys: 3.175 ± 0.375
4.921LeuAsp: 4.921 ± 0.762
3.334LeuGlu: 3.334 ± 0.382
3.334LeuPhe: 3.334 ± 0.575
3.969LeuGly: 3.969 ± 0.948
3.016LeuHis: 3.016 ± 0.722
7.302LeuIle: 7.302 ± 0.778
3.969LeuLys: 3.969 ± 0.412
6.905LeuLeu: 6.905 ± 1.116
1.27LeuMet: 1.27 ± 0.765
4.604LeuAsn: 4.604 ± 0.905
4.604LeuPro: 4.604 ± 1.095
2.778LeuGln: 2.778 ± 0.356
3.81LeuArg: 3.81 ± 0.628
7.699LeuSer: 7.699 ± 0.98
8.334LeuThr: 8.334 ± 1.288
2.778LeuVal: 2.778 ± 1.484
0.556LeuTrp: 0.556 ± 0.174
3.334LeuTyr: 3.334 ± 0.536
0.0LeuXaa: 0.0 ± 0.0
Met
1.191MetAla: 1.191 ± 0.257
0.317MetCys: 0.317 ± 0.102
0.714MetAsp: 0.714 ± 0.28
0.714MetGlu: 0.714 ± 0.204
0.317MetPhe: 0.317 ± 0.067
0.476MetGly: 0.476 ± 0.867
0.873MetHis: 0.873 ± 0.125
1.508MetIle: 1.508 ± 2.516
0.873MetLys: 0.873 ± 0.189
0.714MetLeu: 0.714 ± 0.137
0.317MetMet: 0.317 ± 0.102
0.635MetAsn: 0.635 ± 0.233
0.556MetPro: 0.556 ± 0.219
0.238MetGln: 0.238 ± 0.361
0.476MetArg: 0.476 ± 0.868
0.952MetSer: 0.952 ± 0.187
1.905MetThr: 1.905 ± 0.226
0.873MetVal: 0.873 ± 0.125
0.159MetTrp: 0.159 ± 0.051
0.476MetTyr: 0.476 ± 0.137
0.0MetXaa: 0.0 ± 0.0
Asn
3.969AsnAla: 3.969 ± 0.321
1.111AsnCys: 1.111 ± 0.424
3.095AsnAsp: 3.095 ± 0.238
2.619AsnGlu: 2.619 ± 0.318
2.461AsnPhe: 2.461 ± 0.332
3.651AsnGly: 3.651 ± 0.309
1.587AsnHis: 1.587 ± 0.784
5.397AsnIle: 5.397 ± 0.771
2.778AsnLys: 2.778 ± 0.326
3.095AsnLeu: 3.095 ± 0.495
0.714AsnMet: 0.714 ± 0.605
3.572AsnAsn: 3.572 ± 0.817
3.492AsnPro: 3.492 ± 0.613
1.826AsnGln: 1.826 ± 0.29
1.826AsnArg: 1.826 ± 0.438
3.81AsnSer: 3.81 ± 1.507
7.064AsnThr: 7.064 ± 1.443
2.937AsnVal: 2.937 ± 0.69
0.556AsnTrp: 0.556 ± 0.065
1.349AsnTyr: 1.349 ± 0.159
0.0AsnXaa: 0.0 ± 0.0
Pro
3.175ProAla: 3.175 ± 0.52
1.27ProCys: 1.27 ± 0.245
2.064ProAsp: 2.064 ± 0.231
2.381ProGlu: 2.381 ± 0.305
2.143ProPhe: 2.143 ± 1.775
1.984ProGly: 1.984 ± 1.471
1.27ProHis: 1.27 ± 0.267
3.175ProIle: 3.175 ± 0.188
2.064ProLys: 2.064 ± 0.15
3.651ProLeu: 3.651 ± 0.99
0.238ProMet: 0.238 ± 0.533
2.222ProAsn: 2.222 ± 1.957
2.381ProPro: 2.381 ± 0.815
1.191ProGln: 1.191 ± 0.423
2.461ProArg: 2.461 ± 0.858
4.604ProSer: 4.604 ± 0.437
4.365ProThr: 4.365 ± 0.598
3.889ProVal: 3.889 ± 0.283
0.238ProTrp: 0.238 ± 0.069
2.937ProTyr: 2.937 ± 0.375
0.0ProXaa: 0.0 ± 0.0
Gln
2.699GlnAla: 2.699 ± 0.927
1.191GlnCys: 1.191 ± 0.54
1.032GlnAsp: 1.032 ± 0.273
0.714GlnGlu: 0.714 ± 0.153
2.381GlnPhe: 2.381 ± 0.332
1.27GlnGly: 1.27 ± 1.033
1.27GlnHis: 1.27 ± 0.245
3.969GlnIle: 3.969 ± 0.502
1.191GlnLys: 1.191 ± 0.958
3.572GlnLeu: 3.572 ± 0.513
0.397GlnMet: 0.397 ± 0.216
0.873GlnAsn: 0.873 ± 0.133
1.191GlnPro: 1.191 ± 0.487
1.111GlnGln: 1.111 ± 0.85
1.746GlnArg: 1.746 ± 0.266
2.222GlnSer: 2.222 ± 0.483
2.461GlnThr: 2.461 ± 0.367
1.905GlnVal: 1.905 ± 0.226
0.079GlnTrp: 0.079 ± 0.119
1.984GlnTyr: 1.984 ± 0.227
0.0GlnXaa: 0.0 ± 0.0
Arg
1.905ArgAla: 1.905 ± 0.327
1.349ArgCys: 1.349 ± 0.286
3.016ArgAsp: 3.016 ± 0.589
1.508ArgGlu: 1.508 ± 0.449
3.254ArgPhe: 3.254 ± 0.611
2.381ArgGly: 2.381 ± 0.864
2.302ArgHis: 2.302 ± 0.312
2.222ArgIle: 2.222 ± 0.329
1.27ArgLys: 1.27 ± 0.381
4.048ArgLeu: 4.048 ± 0.486
0.476ArgMet: 0.476 ± 0.229
2.222ArgAsn: 2.222 ± 0.853
1.429ArgPro: 1.429 ± 0.433
1.032ArgGln: 1.032 ± 0.179
2.619ArgArg: 2.619 ± 0.669
4.048ArgSer: 4.048 ± 0.3
2.619ArgThr: 2.619 ± 0.338
3.81ArgVal: 3.81 ± 0.763
0.476ArgTrp: 0.476 ± 0.153
2.064ArgTyr: 2.064 ± 0.189
0.0ArgXaa: 0.0 ± 0.0
Ser
4.365SerAla: 4.365 ± 0.47
2.143SerCys: 2.143 ± 0.396
3.492SerAsp: 3.492 ± 0.736
2.461SerGlu: 2.461 ± 0.265
3.016SerPhe: 3.016 ± 0.997
3.095SerGly: 3.095 ± 0.676
3.492SerHis: 3.492 ± 0.506
5.556SerIle: 5.556 ± 1.366
2.064SerLys: 2.064 ± 0.44
7.302SerLeu: 7.302 ± 0.684
1.27SerMet: 1.27 ± 0.76
3.651SerAsn: 3.651 ± 0.531
3.334SerPro: 3.334 ± 1.117
2.937SerGln: 2.937 ± 0.629
2.699SerArg: 2.699 ± 0.351
7.382SerSer: 7.382 ± 0.732
6.508SerThr: 6.508 ± 0.699
3.81SerVal: 3.81 ± 0.57
0.079SerTrp: 0.079 ± 0.119
5.794SerTyr: 5.794 ± 0.624
0.0SerXaa: 0.0 ± 0.0
Thr
5.477ThrAla: 5.477 ± 0.491
2.381ThrCys: 2.381 ± 0.557
3.413ThrAsp: 3.413 ± 0.429
2.461ThrGlu: 2.461 ± 0.276
3.969ThrPhe: 3.969 ± 0.45
3.651ThrGly: 3.651 ± 0.411
4.207ThrHis: 4.207 ± 0.576
6.112ThrIle: 6.112 ± 0.772
4.365ThrLys: 4.365 ± 0.484
11.271ThrLeu: 11.271 ± 1.97
1.032ThrMet: 1.032 ± 1.137
4.207ThrAsn: 4.207 ± 0.597
4.683ThrPro: 4.683 ± 0.705
3.889ThrGln: 3.889 ± 1.032
4.207ThrArg: 4.207 ± 0.756
6.429ThrSer: 6.429 ± 0.864
8.731ThrThr: 8.731 ± 0.505
4.683ThrVal: 4.683 ± 0.713
1.111ThrTrp: 1.111 ± 0.129
4.683ThrTyr: 4.683 ± 0.31
0.0ThrXaa: 0.0 ± 0.0
Val
2.619ValAla: 2.619 ± 0.374
1.508ValCys: 1.508 ± 0.317
3.016ValAsp: 3.016 ± 0.365
2.461ValGlu: 2.461 ± 0.215
1.746ValPhe: 1.746 ± 0.484
3.095ValGly: 3.095 ± 0.509
0.794ValHis: 0.794 ± 0.111
3.889ValIle: 3.889 ± 0.7
2.302ValLys: 2.302 ± 0.933
3.572ValLeu: 3.572 ± 0.662
0.714ValMet: 0.714 ± 0.086
4.445ValAsn: 4.445 ± 0.776
2.619ValPro: 2.619 ± 0.844
1.27ValGln: 1.27 ± 0.277
3.334ValArg: 3.334 ± 0.309
3.492ValSer: 3.492 ± 0.422
5.08ValThr: 5.08 ± 0.434
2.302ValVal: 2.302 ± 0.353
0.317ValTrp: 0.317 ± 0.111
3.572ValTyr: 3.572 ± 0.654
0.0ValXaa: 0.0 ± 0.0
Trp
0.794TrpAla: 0.794 ± 0.378
0.159TrpCys: 0.159 ± 0.051
0.079TrpAsp: 0.079 ± 0.119
0.317TrpGlu: 0.317 ± 0.067
0.476TrpPhe: 0.476 ± 0.137
0.714TrpGly: 0.714 ± 0.204
0.476TrpHis: 0.476 ± 0.153
0.556TrpIle: 0.556 ± 0.065
0.476TrpLys: 0.476 ± 0.835
0.556TrpLeu: 0.556 ± 0.177
0.079TrpMet: 0.079 ± 0.119
0.873TrpAsn: 0.873 ± 0.158
0.238TrpPro: 0.238 ± 0.069
0.238TrpGln: 0.238 ± 0.069
0.159TrpArg: 0.159 ± 0.051
0.556TrpSer: 0.556 ± 0.558
0.397TrpThr: 0.397 ± 0.234
0.317TrpVal: 0.317 ± 0.111
0.0TrpTrp: 0.0 ± 0.0
0.397TrpTyr: 0.397 ± 0.08
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.778TyrAla: 2.778 ± 0.284
1.429TyrCys: 1.429 ± 0.408
3.572TyrAsp: 3.572 ± 0.714
1.984TyrGlu: 1.984 ± 0.322
1.984TyrPhe: 1.984 ± 0.307
1.27TyrGly: 1.27 ± 0.2
2.064TyrHis: 2.064 ± 0.255
4.365TyrIle: 4.365 ± 0.609
2.302TyrLys: 2.302 ± 0.396
3.73TyrLeu: 3.73 ± 0.962
0.952TyrMet: 0.952 ± 0.145
4.921TyrAsn: 4.921 ± 0.533
2.302TyrPro: 2.302 ± 0.598
2.302TyrGln: 2.302 ± 0.308
2.778TyrArg: 2.778 ± 0.289
4.207TyrSer: 4.207 ± 0.469
7.382TyrThr: 7.382 ± 0.823
1.746TyrVal: 1.746 ± 0.266
0.0TyrTrp: 0.0 ± 0.0
2.937TyrTyr: 2.937 ± 0.334
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (12600 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski