Amino acid dipepetide frequency for Schwartzia succinivorans DSM 10502

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.618AlaAla: 10.618 ± 0.179	1.098AlaCys: 1.098 ± 0.046	5.391AlaAsp: 5.391 ± 0.103	7.062AlaGlu: 7.062 ± 0.116	3.456AlaPhe: 3.456 ± 0.075	7.07AlaGly: 7.07 ± 0.125	1.525AlaHis: 1.525 ± 0.044	4.852AlaIle: 4.852 ± 0.083	5.49AlaLys: 5.49 ± 0.1	8.147AlaLeu: 8.147 ± 0.119	2.752AlaMet: 2.752 ± 0.07	2.759AlaAsn: 2.759 ± 0.078	2.783AlaPro: 2.783 ± 0.072	2.766AlaGln: 2.766 ± 0.07	3.776AlaArg: 3.776 ± 0.081	4.591AlaSer: 4.591 ± 0.079	3.067AlaThr: 3.067 ± 0.071	7.994AlaVal: 7.994 ± 0.112	0.773AlaTrp: 0.773 ± 0.03	2.633AlaTyr: 2.633 ± 0.065	0.0AlaXaa: 0.0 ± 0.0
Cys	0.964CysAla: 0.964 ± 0.038	0.223CysCys: 0.223 ± 0.021	0.704CysAsp: 0.704 ± 0.029	0.745CysGlu: 0.745 ± 0.033	0.557CysPhe: 0.557 ± 0.026	1.365CysGly: 1.365 ± 0.045	0.274CysHis: 0.274 ± 0.02	0.86CysIle: 0.86 ± 0.034	0.548CysLys: 0.548 ± 0.025	1.055CysLeu: 1.055 ± 0.041	0.384CysMet: 0.384 ± 0.024	0.398CysAsn: 0.398 ± 0.026	0.617CysPro: 0.617 ± 0.037	0.282CysGln: 0.282 ± 0.019	0.793CysArg: 0.793 ± 0.036	0.728CysSer: 0.728 ± 0.035	0.54CysThr: 0.54 ± 0.026	0.871CysVal: 0.871 ± 0.037	0.103CysTrp: 0.103 ± 0.012	0.434CysTyr: 0.434 ± 0.025	0.0CysXaa: 0.0 ± 0.0
Asp	5.219AspAla: 5.219 ± 0.089	0.698AspCys: 0.698 ± 0.029	3.355AspAsp: 3.355 ± 0.067	5.033AspGlu: 5.033 ± 0.086	2.789AspPhe: 2.789 ± 0.056	4.583AspGly: 4.583 ± 0.101	0.808AspHis: 0.808 ± 0.035	4.716AspIle: 4.716 ± 0.083	3.712AspLys: 3.712 ± 0.077	4.154AspLeu: 4.154 ± 0.076	1.933AspMet: 1.933 ± 0.044	2.181AspAsn: 2.181 ± 0.059	1.7AspPro: 1.7 ± 0.05	0.908AspGln: 0.908 ± 0.029	2.688AspArg: 2.688 ± 0.067	2.998AspSer: 2.998 ± 0.081	3.075AspThr: 3.075 ± 0.065	4.519AspVal: 4.519 ± 0.086	0.598AspTrp: 0.598 ± 0.026	2.523AspTyr: 2.523 ± 0.063	0.0AspXaa: 0.0 ± 0.0
Glu	6.881GluAla: 6.881 ± 0.115	0.695GluCys: 0.695 ± 0.026	3.82GluAsp: 3.82 ± 0.069	6.073GluGlu: 6.073 ± 0.124	2.441GluPhe: 2.441 ± 0.053	4.426GluGly: 4.426 ± 0.081	1.521GluHis: 1.521 ± 0.047	5.017GluIle: 5.017 ± 0.087	6.64GluLys: 6.64 ± 0.117	7.026GluLeu: 7.026 ± 0.104	2.276GluMet: 2.276 ± 0.059	3.542GluAsn: 3.542 ± 0.071	2.172GluPro: 2.172 ± 0.057	2.553GluGln: 2.553 ± 0.059	3.809GluArg: 3.809 ± 0.085	3.368GluSer: 3.368 ± 0.073	3.624GluThr: 3.624 ± 0.081	4.383GluVal: 4.383 ± 0.08	0.703GluTrp: 0.703 ± 0.032	2.756GluTyr: 2.756 ± 0.058	0.0GluXaa: 0.0 ± 0.0
Phe	3.44PheAla: 3.44 ± 0.075	0.661PheCys: 0.661 ± 0.029	2.596PheAsp: 2.596 ± 0.06	2.444PheGlu: 2.444 ± 0.058	2.012PhePhe: 2.012 ± 0.065	3.19PheGly: 3.19 ± 0.073	0.803PheHis: 0.803 ± 0.031	2.615PheIle: 2.615 ± 0.059	1.76PheLys: 1.76 ± 0.046	3.823PheLeu: 3.823 ± 0.089	1.201PheMet: 1.201 ± 0.042	1.501PheAsn: 1.501 ± 0.047	1.433PhePro: 1.433 ± 0.046	0.986PheGln: 0.986 ± 0.04	1.896PheArg: 1.896 ± 0.053	2.917PheSer: 2.917 ± 0.065	2.278PheThr: 2.278 ± 0.053	2.915PheVal: 2.915 ± 0.073	0.48PheTrp: 0.48 ± 0.027	1.453PheTyr: 1.453 ± 0.055	0.0PheXaa: 0.0 ± 0.0
Gly	6.273GlyAla: 6.273 ± 0.123	1.079GlyCys: 1.079 ± 0.039	3.815GlyAsp: 3.815 ± 0.09	4.764GlyGlu: 4.764 ± 0.09	3.097GlyPhe: 3.097 ± 0.067	5.575GlyGly: 5.575 ± 0.131	1.585GlyHis: 1.585 ± 0.045	5.831GlyIle: 5.831 ± 0.096	5.32GlyLys: 5.32 ± 0.087	6.049GlyLeu: 6.049 ± 0.095	2.513GlyMet: 2.513 ± 0.068	2.81GlyAsn: 2.81 ± 0.099	1.591GlyPro: 1.591 ± 0.05	2.04GlyGln: 2.04 ± 0.044	3.776GlyArg: 3.776 ± 0.073	4.236GlySer: 4.236 ± 0.096	4.617GlyThr: 4.617 ± 0.131	5.502GlyVal: 5.502 ± 0.095	0.859GlyTrp: 0.859 ± 0.034	2.771GlyTyr: 2.771 ± 0.057	0.0GlyXaa: 0.0 ± 0.0
His	1.488HisAla: 1.488 ± 0.042	0.287HisCys: 0.287 ± 0.022	1.143HisAsp: 1.143 ± 0.041	1.278HisGlu: 1.278 ± 0.041	0.891HisPhe: 0.891 ± 0.038	1.614HisGly: 1.614 ± 0.04	0.481HisHis: 0.481 ± 0.031	1.457HisIle: 1.457 ± 0.05	0.981HisLys: 0.981 ± 0.032	1.642HisLeu: 1.642 ± 0.045	0.573HisMet: 0.573 ± 0.03	0.705HisAsn: 0.705 ± 0.03	1.069HisPro: 1.069 ± 0.038	0.457HisGln: 0.457 ± 0.025	0.928HisArg: 0.928 ± 0.04	1.065HisSer: 1.065 ± 0.036	1.069HisThr: 1.069 ± 0.036	1.325HisVal: 1.325 ± 0.041	0.217HisTrp: 0.217 ± 0.017	0.67HisTyr: 0.67 ± 0.03	0.0HisXaa: 0.0 ± 0.0
Ile	5.869IleAla: 5.869 ± 0.087	0.886IleCys: 0.886 ± 0.037	4.263IleAsp: 4.263 ± 0.082	4.611IleGlu: 4.611 ± 0.082	2.576IlePhe: 2.576 ± 0.059	4.983IleGly: 4.983 ± 0.103	1.273IleHis: 1.273 ± 0.04	4.101IleIle: 4.101 ± 0.092	3.801IleLys: 3.801 ± 0.073	6.005IleLeu: 6.005 ± 0.111	1.76IleMet: 1.76 ± 0.049	2.439IleAsn: 2.439 ± 0.066	2.997IlePro: 2.997 ± 0.066	1.918IleGln: 1.918 ± 0.049	3.523IleArg: 3.523 ± 0.075	4.215IleSer: 4.215 ± 0.07	3.607IleThr: 3.607 ± 0.074	4.752IleVal: 4.752 ± 0.091	0.521IleTrp: 0.521 ± 0.027	2.157IleTyr: 2.157 ± 0.056	0.0IleXaa: 0.0 ± 0.0
Lys	5.602LysAla: 5.602 ± 0.095	0.559LysCys: 0.559 ± 0.03	3.864LysAsp: 3.864 ± 0.088	5.649LysGlu: 5.649 ± 0.101	1.929LysPhe: 1.929 ± 0.05	4.077LysGly: 4.077 ± 0.07	1.111LysHis: 1.111 ± 0.038	4.264LysIle: 4.264 ± 0.075	5.672LysLys: 5.672 ± 0.115	5.529LysLeu: 5.529 ± 0.091	2.045LysMet: 2.045 ± 0.053	3.427LysAsn: 3.427 ± 0.077	2.179LysPro: 2.179 ± 0.059	2.054LysGln: 2.054 ± 0.057	3.267LysArg: 3.267 ± 0.063	3.199LysSer: 3.199 ± 0.07	3.518LysThr: 3.518 ± 0.069	3.964LysVal: 3.964 ± 0.078	0.58LysTrp: 0.58 ± 0.031	2.387LysTyr: 2.387 ± 0.063	0.0LysXaa: 0.0 ± 0.0
Leu	8.011LeuAla: 8.011 ± 0.125	1.239LeuCys: 1.239 ± 0.041	5.049LeuAsp: 5.049 ± 0.076	5.762LeuGlu: 5.762 ± 0.107	3.683LeuPhe: 3.683 ± 0.089	6.411LeuGly: 6.411 ± 0.095	1.846LeuHis: 1.846 ± 0.05	5.094LeuIle: 5.094 ± 0.093	5.743LeuLys: 5.743 ± 0.092	8.545LeuLeu: 8.545 ± 0.152	2.766LeuMet: 2.766 ± 0.062	3.334LeuAsn: 3.334 ± 0.06	4.049LeuPro: 4.049 ± 0.077	2.6LeuGln: 2.6 ± 0.053	4.879LeuArg: 4.879 ± 0.092	6.347LeuSer: 6.347 ± 0.098	5.111LeuThr: 5.111 ± 0.09	5.801LeuVal: 5.801 ± 0.103	0.776LeuTrp: 0.776 ± 0.035	2.842LeuTyr: 2.842 ± 0.068	0.0LeuXaa: 0.0 ± 0.0
Met	2.771MetAla: 2.771 ± 0.073	0.274MetCys: 0.274 ± 0.02	1.897MetAsp: 1.897 ± 0.052	2.329MetGlu: 2.329 ± 0.062	0.993MetPhe: 0.993 ± 0.039	2.166MetGly: 2.166 ± 0.059	0.535MetHis: 0.535 ± 0.025	1.768MetIle: 1.768 ± 0.052	2.347MetLys: 2.347 ± 0.058	2.995MetLeu: 2.995 ± 0.069	0.93MetMet: 0.93 ± 0.037	1.398MetAsn: 1.398 ± 0.044	1.367MetPro: 1.367 ± 0.046	1.192MetGln: 1.192 ± 0.043	1.651MetArg: 1.651 ± 0.044	1.71MetSer: 1.71 ± 0.046	1.857MetThr: 1.857 ± 0.06	1.809MetVal: 1.809 ± 0.057	0.195MetTrp: 0.195 ± 0.016	0.793MetTyr: 0.793 ± 0.035	0.0MetXaa: 0.0 ± 0.0
Asn	3.354AsnAla: 3.354 ± 0.085	0.466AsnCys: 0.466 ± 0.026	2.143AsnAsp: 2.143 ± 0.056	2.522AsnGlu: 2.522 ± 0.056	1.663AsnPhe: 1.663 ± 0.051	3.231AsnGly: 3.231 ± 0.111	0.776AsnHis: 0.776 ± 0.036	3.115AsnIle: 3.115 ± 0.065	2.144AsnLys: 2.144 ± 0.056	3.401AsnLeu: 3.401 ± 0.078	1.191AsnMet: 1.191 ± 0.041	1.642AsnAsn: 1.642 ± 0.071	1.987AsnPro: 1.987 ± 0.052	1.054AsnGln: 1.054 ± 0.04	1.962AsnArg: 1.962 ± 0.048	1.957AsnSer: 1.957 ± 0.057	2.079AsnThr: 2.079 ± 0.07	2.862AsnVal: 2.862 ± 0.088	0.383AsnTrp: 0.383 ± 0.021	1.37AsnTyr: 1.37 ± 0.051	0.0AsnXaa: 0.0 ± 0.0
Pro	3.003ProAla: 3.003 ± 0.073	0.46ProCys: 0.46 ± 0.023	2.461ProAsp: 2.461 ± 0.054	3.631ProGlu: 3.631 ± 0.076	1.615ProPhe: 1.615 ± 0.044	2.556ProGly: 2.556 ± 0.055	0.783ProHis: 0.783 ± 0.036	2.177ProIle: 2.177 ± 0.055	2.156ProLys: 2.156 ± 0.06	3.092ProLeu: 3.092 ± 0.063	1.121ProMet: 1.121 ± 0.044	1.259ProAsn: 1.259 ± 0.045	1.118ProPro: 1.118 ± 0.041	1.223ProGln: 1.223 ± 0.042	1.44ProArg: 1.44 ± 0.045	2.012ProSer: 2.012 ± 0.057	1.738ProThr: 1.738 ± 0.042	3.284ProVal: 3.284 ± 0.066	0.34ProTrp: 0.34 ± 0.025	1.351ProTyr: 1.351 ± 0.048	0.0ProXaa: 0.0 ± 0.0
Gln	2.674GlnAla: 2.674 ± 0.067	0.297GlnCys: 0.297 ± 0.02	1.482GlnAsp: 1.482 ± 0.037	2.171GlnGlu: 2.171 ± 0.053	1.014GlnPhe: 1.014 ± 0.033	1.823GlnGly: 1.823 ± 0.046	0.575GlnHis: 0.575 ± 0.026	1.986GlnIle: 1.986 ± 0.048	2.314GlnLys: 2.314 ± 0.058	2.611GlnLeu: 2.611 ± 0.069	1.027GlnMet: 1.027 ± 0.036	1.331GlnAsn: 1.331 ± 0.044	1.098GlnPro: 1.098 ± 0.038	1.269GlnGln: 1.269 ± 0.054	1.637GlnArg: 1.637 ± 0.051	1.597GlnSer: 1.597 ± 0.046	1.556GlnThr: 1.556 ± 0.043	1.698GlnVal: 1.698 ± 0.044	0.251GlnTrp: 0.251 ± 0.016	1.094GlnTyr: 1.094 ± 0.042	0.0GlnXaa: 0.0 ± 0.0
Arg	3.716ArgAla: 3.716 ± 0.074	0.598ArgCys: 0.598 ± 0.031	2.698ArgAsp: 2.698 ± 0.064	4.127ArgGlu: 4.127 ± 0.076	2.066ArgPhe: 2.066 ± 0.047	3.138ArgGly: 3.138 ± 0.072	1.005ArgHis: 1.005 ± 0.034	3.741ArgIle: 3.741 ± 0.072	3.155ArgLys: 3.155 ± 0.074	4.771ArgLeu: 4.771 ± 0.096	1.744ArgMet: 1.744 ± 0.048	1.964ArgAsn: 1.964 ± 0.044	1.749ArgPro: 1.749 ± 0.055	1.78ArgGln: 1.78 ± 0.052	3.051ArgArg: 3.051 ± 0.081	2.48ArgSer: 2.48 ± 0.056	2.395ArgThr: 2.395 ± 0.061	3.479ArgVal: 3.479 ± 0.076	0.52ArgTrp: 0.52 ± 0.028	1.897ArgTyr: 1.897 ± 0.048	0.0ArgXaa: 0.0 ± 0.0
Ser	4.949SerAla: 4.949 ± 0.1	0.739SerCys: 0.739 ± 0.034	3.347SerAsp: 3.347 ± 0.077	3.967SerGlu: 3.967 ± 0.07	2.595SerPhe: 2.595 ± 0.066	4.978SerGly: 4.978 ± 0.118	1.063SerHis: 1.063 ± 0.039	3.648SerIle: 3.648 ± 0.075	3.082SerLys: 3.082 ± 0.07	5.116SerLeu: 5.116 ± 0.089	1.78SerMet: 1.78 ± 0.053	2.033SerAsn: 2.033 ± 0.068	1.962SerPro: 1.962 ± 0.043	1.511SerGln: 1.511 ± 0.045	2.827SerArg: 2.827 ± 0.064	3.415SerSer: 3.415 ± 0.091	2.643SerThr: 2.643 ± 0.074	4.414SerVal: 4.414 ± 0.084	0.544SerTrp: 0.544 ± 0.026	2.017SerTyr: 2.017 ± 0.052	0.0SerXaa: 0.0 ± 0.0
Thr	5.06ThrAla: 5.06 ± 0.111	0.529ThrCys: 0.529 ± 0.028	2.985ThrAsp: 2.985 ± 0.072	3.679ThrGlu: 3.679 ± 0.067	1.998ThrPhe: 1.998 ± 0.058	4.685ThrGly: 4.685 ± 0.123	0.961ThrHis: 0.961 ± 0.032	3.44ThrIle: 3.44 ± 0.076	2.917ThrLys: 2.917 ± 0.068	4.795ThrLeu: 4.795 ± 0.084	1.491ThrMet: 1.491 ± 0.049	1.842ThrAsn: 1.842 ± 0.065	2.275ThrPro: 2.275 ± 0.057	1.424ThrGln: 1.424 ± 0.042	2.15ThrArg: 2.15 ± 0.047	2.603ThrSer: 2.603 ± 0.075	2.757ThrThr: 2.757 ± 0.079	4.438ThrVal: 4.438 ± 0.1	0.433ThrTrp: 0.433 ± 0.024	1.667ThrTyr: 1.667 ± 0.055	0.0ThrXaa: 0.0 ± 0.0
Val	5.362ValAla: 5.362 ± 0.094	1.061ValCys: 1.061 ± 0.037	4.223ValAsp: 4.223 ± 0.087	4.747ValGlu: 4.747 ± 0.076	3.111ValPhe: 3.111 ± 0.067	4.801ValGly: 4.801 ± 0.107	1.369ValHis: 1.369 ± 0.034	4.704ValIle: 4.704 ± 0.09	4.494ValLys: 4.494 ± 0.077	7.021ValLeu: 7.021 ± 0.096	2.212ValMet: 2.212 ± 0.061	2.819ValAsn: 2.819 ± 0.093	3.047ValPro: 3.047 ± 0.062	2.079ValGln: 2.079 ± 0.05	3.627ValArg: 3.627 ± 0.071	4.706ValSer: 4.706 ± 0.083	4.191ValThr: 4.191 ± 0.104	5.341ValVal: 5.341 ± 0.105	0.652ValTrp: 0.652 ± 0.03	2.596ValTyr: 2.596 ± 0.056	0.0ValXaa: 0.0 ± 0.0
Trp	0.614TrpAla: 0.614 ± 0.027	0.137TrpCys: 0.137 ± 0.015	0.496TrpAsp: 0.496 ± 0.025	0.682TrpGlu: 0.682 ± 0.033	0.388TrpPhe: 0.388 ± 0.025	0.619TrpGly: 0.619 ± 0.032	0.252TrpHis: 0.252 ± 0.017	0.584TrpIle: 0.584 ± 0.03	0.715TrpLys: 0.715 ± 0.029	1.014TrpLeu: 1.014 ± 0.04	0.365TrpMet: 0.365 ± 0.025	0.49TrpAsn: 0.49 ± 0.026	0.28TrpPro: 0.28 ± 0.019	0.38TrpGln: 0.38 ± 0.023	0.531TrpArg: 0.531 ± 0.026	0.461TrpSer: 0.461 ± 0.023	0.442TrpThr: 0.442 ± 0.026	0.519TrpVal: 0.519 ± 0.027	0.11TrpTrp: 0.11 ± 0.012	0.344TrpTyr: 0.344 ± 0.023	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.733TyrAla: 2.733 ± 0.059	0.46TyrCys: 0.46 ± 0.025	2.454TyrAsp: 2.454 ± 0.068	2.449TyrGlu: 2.449 ± 0.058	1.53TyrPhe: 1.53 ± 0.049	2.812TyrGly: 2.812 ± 0.069	0.794TyrHis: 0.794 ± 0.034	2.286TyrIle: 2.286 ± 0.069	1.886TyrLys: 1.886 ± 0.052	3.099TyrLeu: 3.099 ± 0.07	0.914TyrMet: 0.914 ± 0.034	1.427TyrAsn: 1.427 ± 0.045	1.347TyrPro: 1.347 ± 0.051	1.03TyrGln: 1.03 ± 0.036	1.862TyrArg: 1.862 ± 0.051	2.026TyrSer: 2.026 ± 0.056	1.967TyrThr: 1.967 ± 0.05	2.295TyrVal: 2.295 ± 0.058	0.387TyrTrp: 0.387 ± 0.026	1.396TyrTyr: 1.396 ± 0.046	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2426 proteins (794237 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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