Human circular dsDNA virus associated with alcoholic cirrhosis

Taxonomy: Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses

Average proteome isoelectric point is 9.16

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 1 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|E0D6T0|E0D6T0_9VIRU Uncharacterized protein Hili OS=Human circular dsDNA virus associated with alcoholic cirrhosis OX=749224 GN=Hili PE=4 SV=1
MM1 pKa = 7.31SRR3 pKa = 11.84EE4 pKa = 4.26LVSSSSYY11 pKa = 10.11PLSNPTPSSSMKK23 pKa = 10.03SSQSRR28 pKa = 11.84IPVKK32 pKa = 10.55AKK34 pKa = 9.91RR35 pKa = 11.84APLGEE40 pKa = 3.91RR41 pKa = 11.84VDD43 pKa = 4.04NHH45 pKa = 6.55DD46 pKa = 3.32HH47 pKa = 5.13TTPRR51 pKa = 11.84QHH53 pKa = 6.38LVKK56 pKa = 10.26SVKK59 pKa = 10.22SVIRR63 pKa = 11.84PRR65 pKa = 11.84IISTKK70 pKa = 9.29STASPSKK77 pKa = 10.11SSTYY81 pKa = 10.15RR82 pKa = 11.84PSPRR86 pKa = 11.84AAVQGSPSSSIVSSPAGANVSRR108 pKa = 11.84PGHH111 pKa = 5.18TPHH114 pKa = 7.33PRR116 pKa = 11.84RR117 pKa = 11.84SSVGLAFLGHH127 pKa = 6.55DD128 pKa = 3.66VSMLMDD134 pKa = 3.9TTRR137 pKa = 11.84LDD139 pKa = 3.94FVSDD143 pKa = 3.68TDD145 pKa = 4.24DD146 pKa = 4.31SEE148 pKa = 5.77GDD150 pKa = 3.55EE151 pKa = 4.82PLDD154 pKa = 3.48NMLVRR159 pKa = 11.84RR160 pKa = 11.84GVMGPGRR167 pKa = 11.84LMTPANSQEE176 pKa = 4.26SQVSSLCLLEE186 pKa = 4.8SQLTCSPTLSSILL199 pKa = 3.71

Molecular weight: 21.28 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|E0D6T0|E0D6T0_9VIRU Uncharacterized protein Hili OS=Human circular dsDNA virus associated with alcoholic cirrhosis OX=749224 GN=Hili PE=4 SV=1
MM1 pKa = 7.31SRR3 pKa = 11.84EE4 pKa = 4.26LVSSSSYY11 pKa = 10.11PLSNPTPSSSMKK23 pKa = 10.03SSQSRR28 pKa = 11.84IPVKK32 pKa = 10.55AKK34 pKa = 9.91RR35 pKa = 11.84APLGEE40 pKa = 3.91RR41 pKa = 11.84VDD43 pKa = 4.04NHH45 pKa = 6.55DD46 pKa = 3.32HH47 pKa = 5.13TTPRR51 pKa = 11.84QHH53 pKa = 6.38LVKK56 pKa = 10.26SVKK59 pKa = 10.22SVIRR63 pKa = 11.84PRR65 pKa = 11.84IISTKK70 pKa = 9.29STASPSKK77 pKa = 10.11SSTYY81 pKa = 10.15RR82 pKa = 11.84PSPRR86 pKa = 11.84AAVQGSPSSSIVSSPAGANVSRR108 pKa = 11.84PGHH111 pKa = 5.18TPHH114 pKa = 7.33PRR116 pKa = 11.84RR117 pKa = 11.84SSVGLAFLGHH127 pKa = 6.55DD128 pKa = 3.66VSMLMDD134 pKa = 3.9TTRR137 pKa = 11.84LDD139 pKa = 3.94FVSDD143 pKa = 3.68TDD145 pKa = 4.24DD146 pKa = 4.31SEE148 pKa = 5.77GDD150 pKa = 3.55EE151 pKa = 4.82PLDD154 pKa = 3.48NMLVRR159 pKa = 11.84RR160 pKa = 11.84GVMGPGRR167 pKa = 11.84LMTPANSQEE176 pKa = 4.26SQVSSLCLLEE186 pKa = 4.8SQLTCSPTLSSILL199 pKa = 3.71

Molecular weight: 21.28 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

1

0

1

199

199

199

199.0

21.28

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

4.523 ± 0.0

1.005 ± 0.0

5.025 ± 0.0

3.015 ± 0.0

1.005 ± 0.0

5.025 ± 0.0

3.015 ± 0.0

3.015 ± 0.0

3.518 ± 0.0

8.543 ± 0.0

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

3.518 ± 0.0

2.513 ± 0.0

9.548 ± 0.0

3.015 ± 0.0

8.04 ± 0.0

20.603 ± 0.0

6.533 ± 0.0

7.538 ± 0.0

0.0 ± 0.0

1.005 ± 0.0
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski