Amino acid dipepetide frequency for Beihai picobirna-like virus 7

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.643AlaAla: 3.643 ± 0.988
0.0AlaCys: 0.0 ± 0.0
4.554AlaAsp: 4.554 ± 0.952
0.911AlaGlu: 0.911 ± 0.69
0.911AlaPhe: 0.911 ± 0.559
0.911AlaGly: 0.911 ± 0.69
0.0AlaHis: 0.0 ± 0.0
4.554AlaIle: 4.554 ± 1.547
2.732AlaLys: 2.732 ± 0.821
7.286AlaLeu: 7.286 ± 1.976
2.732AlaMet: 2.732 ± 0.428
0.911AlaAsn: 0.911 ± 0.559
2.732AlaPro: 2.732 ± 0.821
6.375AlaGln: 6.375 ± 2.666
0.911AlaArg: 0.911 ± 0.559
4.554AlaSer: 4.554 ± 2.202
3.643AlaThr: 3.643 ± 0.262
2.732AlaVal: 2.732 ± 0.428
0.0AlaTrp: 0.0 ± 0.0
3.643AlaTyr: 3.643 ± 0.262
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.911CysAsp: 0.911 ± 0.559
0.0CysGlu: 0.0 ± 0.0
0.911CysPhe: 0.911 ± 0.559
0.0CysGly: 0.0 ± 0.0
0.911CysHis: 0.911 ± 0.559
0.0CysIle: 0.0 ± 0.0
0.911CysLys: 0.911 ± 0.69
0.911CysLeu: 0.911 ± 0.559
0.0CysMet: 0.0 ± 0.0
1.821CysAsn: 1.821 ± 1.119
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
1.821CysThr: 1.821 ± 1.119
0.911CysVal: 0.911 ± 0.69
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
5.464AspAla: 5.464 ± 0.857
0.0AspCys: 0.0 ± 0.0
7.286AspAsp: 7.286 ± 1.773
0.911AspGlu: 0.911 ± 0.69
5.464AspPhe: 5.464 ± 0.857
10.018AspGly: 10.018 ± 0.095
0.0AspHis: 0.0 ± 0.0
2.732AspIle: 2.732 ± 2.071
3.643AspLys: 3.643 ± 0.262
2.732AspLeu: 2.732 ± 2.071
0.911AspMet: 0.911 ± 0.559
1.821AspAsn: 1.821 ± 0.131
4.554AspPro: 4.554 ± 0.952
0.911AspGln: 0.911 ± 0.69
0.911AspArg: 0.911 ± 0.559
6.375AspSer: 6.375 ± 1.416
5.464AspThr: 5.464 ± 1.642
2.732AspVal: 2.732 ± 0.428
0.0AspTrp: 0.0 ± 0.0
5.464AspTyr: 5.464 ± 4.142
0.0AspXaa: 0.0 ± 0.0
Glu
0.911GluAla: 0.911 ± 0.69
0.911GluCys: 0.911 ± 0.559
4.554GluAsp: 4.554 ± 3.451
3.643GluGlu: 3.643 ± 1.511
0.911GluPhe: 0.911 ± 0.559
0.911GluGly: 0.911 ± 0.559
0.0GluHis: 0.0 ± 0.0
4.554GluIle: 4.554 ± 0.952
1.821GluLys: 1.821 ± 1.119
3.643GluLeu: 3.643 ± 0.262
0.911GluMet: 0.911 ± 0.69
3.643GluAsn: 3.643 ± 1.511
1.821GluPro: 1.821 ± 0.131
0.911GluGln: 0.911 ± 0.69
1.821GluArg: 1.821 ± 1.381
1.821GluSer: 1.821 ± 0.131
1.821GluThr: 1.821 ± 1.119
2.732GluVal: 2.732 ± 0.428
0.911GluTrp: 0.911 ± 0.559
1.821GluTyr: 1.821 ± 0.131
0.0GluXaa: 0.0 ± 0.0
Phe
2.732PheAla: 2.732 ± 0.428
0.911PheCys: 0.911 ± 0.559
5.464PheAsp: 5.464 ± 0.393
1.821PheGlu: 1.821 ± 0.131
0.911PhePhe: 0.911 ± 0.559
0.911PheGly: 0.911 ± 0.69
1.821PheHis: 1.821 ± 0.131
0.911PheIle: 0.911 ± 0.559
1.821PheLys: 1.821 ± 1.381
2.732PheLeu: 2.732 ± 2.071
0.0PheMet: 0.0 ± 0.0
6.375PheAsn: 6.375 ± 2.666
0.0PhePro: 0.0 ± 0.0
1.821PheGln: 1.821 ± 0.131
4.554PheArg: 4.554 ± 1.547
5.464PheSer: 5.464 ± 0.857
3.643PheThr: 3.643 ± 2.761
0.911PheVal: 0.911 ± 0.559
0.911PheTrp: 0.911 ± 0.559
0.911PheTyr: 0.911 ± 0.559
0.0PheXaa: 0.0 ± 0.0
Gly
4.554GlyAla: 4.554 ± 1.547
0.0GlyCys: 0.0 ± 0.0
2.732GlyAsp: 2.732 ± 0.428
4.554GlyGlu: 4.554 ± 1.547
2.732GlyPhe: 2.732 ± 0.428
10.018GlyGly: 10.018 ± 4.903
0.0GlyHis: 0.0 ± 0.0
6.375GlyIle: 6.375 ± 1.083
3.643GlyLys: 3.643 ± 0.988
7.286GlyLeu: 7.286 ± 1.773
0.911GlyMet: 0.911 ± 0.559
1.821GlyAsn: 1.821 ± 1.119
5.464GlyPro: 5.464 ± 0.393
0.911GlyGln: 0.911 ± 0.69
0.911GlyArg: 0.911 ± 0.559
10.018GlySer: 10.018 ± 3.654
1.821GlyThr: 1.821 ± 1.119
4.554GlyVal: 4.554 ± 0.952
0.911GlyTrp: 0.911 ± 0.69
2.732GlyTyr: 2.732 ± 0.821
0.0GlyXaa: 0.0 ± 0.0
His
1.821HisAla: 1.821 ± 1.119
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.911HisGlu: 0.911 ± 0.69
0.0HisPhe: 0.0 ± 0.0
0.911HisGly: 0.911 ± 0.69
0.0HisHis: 0.0 ± 0.0
0.911HisIle: 0.911 ± 0.559
0.911HisLys: 0.911 ± 0.69
0.0HisLeu: 0.0 ± 0.0
0.0HisMet: 0.0 ± 0.0
1.821HisAsn: 1.821 ± 1.119
0.911HisPro: 0.911 ± 0.69
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
0.911HisSer: 0.911 ± 0.559
0.0HisThr: 0.0 ± 0.0
0.911HisVal: 0.911 ± 0.559
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
2.732IleAla: 2.732 ± 2.071
0.0IleCys: 0.0 ± 0.0
3.643IleAsp: 3.643 ± 1.511
1.821IleGlu: 1.821 ± 1.119
2.732IlePhe: 2.732 ± 0.428
2.732IleGly: 2.732 ± 0.821
0.911IleHis: 0.911 ± 0.559
1.821IleIle: 1.821 ± 1.381
0.911IleLys: 0.911 ± 0.559
5.464IleLeu: 5.464 ± 0.393
0.911IleMet: 0.911 ± 0.901
1.821IleAsn: 1.821 ± 0.131
0.911IlePro: 0.911 ± 0.559
2.732IleGln: 2.732 ± 0.428
1.821IleArg: 1.821 ± 1.119
4.554IleSer: 4.554 ± 2.202
3.643IleThr: 3.643 ± 2.237
6.375IleVal: 6.375 ± 0.167
0.911IleTrp: 0.911 ± 0.559
4.554IleTyr: 4.554 ± 0.952
0.0IleXaa: 0.0 ± 0.0
Lys
8.197LysAla: 8.197 ± 0.036
0.911LysCys: 0.911 ± 0.559
4.554LysAsp: 4.554 ± 2.202
3.643LysGlu: 3.643 ± 1.511
3.643LysPhe: 3.643 ± 0.262
5.464LysGly: 5.464 ± 1.642
0.0LysHis: 0.0 ± 0.0
2.732LysIle: 2.732 ± 1.678
5.464LysLys: 5.464 ± 2.107
6.375LysLeu: 6.375 ± 1.083
0.911LysMet: 0.911 ± 0.69
0.911LysAsn: 0.911 ± 0.69
2.732LysPro: 2.732 ± 1.678
1.821LysGln: 1.821 ± 0.131
1.821LysArg: 1.821 ± 0.131
3.643LysSer: 3.643 ± 0.262
5.464LysThr: 5.464 ± 0.857
3.643LysVal: 3.643 ± 0.262
0.0LysTrp: 0.0 ± 0.0
6.375LysTyr: 6.375 ± 3.582
0.0LysXaa: 0.0 ± 0.0
Leu
2.732LeuAla: 2.732 ± 0.428
0.911LeuCys: 0.911 ± 0.559
5.464LeuAsp: 5.464 ± 0.857
4.554LeuGlu: 4.554 ± 2.202
2.732LeuPhe: 2.732 ± 0.821
3.643LeuGly: 3.643 ± 0.262
0.0LeuHis: 0.0 ± 0.0
5.464LeuIle: 5.464 ± 0.393
8.197LeuLys: 8.197 ± 3.713
4.554LeuLeu: 4.554 ± 0.952
0.911LeuMet: 0.911 ± 0.474
6.375LeuAsn: 6.375 ± 0.167
4.554LeuPro: 4.554 ± 1.547
2.732LeuGln: 2.732 ± 0.821
8.197LeuArg: 8.197 ± 0.036
8.197LeuSer: 8.197 ± 3.713
3.643LeuThr: 3.643 ± 0.988
5.464LeuVal: 5.464 ± 1.642
0.911LeuTrp: 0.911 ± 0.559
4.554LeuTyr: 4.554 ± 0.298
0.0LeuXaa: 0.0 ± 0.0
Met
0.911MetAla: 0.911 ± 0.69
0.911MetCys: 0.911 ± 0.559
0.0MetAsp: 0.0 ± 0.0
0.0MetGlu: 0.0 ± 0.0
0.911MetPhe: 0.911 ± 0.69
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.911MetIle: 0.911 ± 0.559
0.0MetLys: 0.0 ± 0.0
0.911MetLeu: 0.911 ± 0.559
0.911MetMet: 0.911 ± 0.559
1.821MetAsn: 1.821 ± 1.381
0.911MetPro: 0.911 ± 0.559
1.821MetGln: 1.821 ± 1.381
0.911MetArg: 0.911 ± 0.69
2.732MetSer: 2.732 ± 0.428
0.911MetThr: 0.911 ± 0.559
1.821MetVal: 1.821 ± 1.119
0.0MetTrp: 0.0 ± 0.0
0.911MetTyr: 0.911 ± 0.559
0.0MetXaa: 0.0 ± 0.0
Asn
0.911AsnAla: 0.911 ± 0.69
0.911AsnCys: 0.911 ± 0.69
2.732AsnAsp: 2.732 ± 0.428
1.821AsnGlu: 1.821 ± 0.131
5.464AsnPhe: 5.464 ± 0.393
1.821AsnGly: 1.821 ± 1.119
0.0AsnHis: 0.0 ± 0.0
1.821AsnIle: 1.821 ± 1.119
6.375AsnLys: 6.375 ± 2.666
11.84AsnLeu: 11.84 ± 0.226
0.911AsnMet: 0.911 ± 0.559
7.286AsnAsn: 7.286 ± 3.225
4.554AsnPro: 4.554 ± 2.797
2.732AsnGln: 2.732 ± 1.678
1.821AsnArg: 1.821 ± 1.381
6.375AsnSer: 6.375 ± 2.333
2.732AsnThr: 2.732 ± 0.428
1.821AsnVal: 1.821 ± 1.119
2.732AsnTrp: 2.732 ± 0.428
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
1.821ProAla: 1.821 ± 1.119
0.911ProCys: 0.911 ± 0.69
3.643ProAsp: 3.643 ± 1.511
2.732ProGlu: 2.732 ± 0.428
0.911ProPhe: 0.911 ± 0.559
6.375ProGly: 6.375 ± 3.916
0.911ProHis: 0.911 ± 0.69
3.643ProIle: 3.643 ± 1.511
2.732ProLys: 2.732 ± 0.428
3.643ProLeu: 3.643 ± 0.262
1.821ProMet: 1.821 ± 0.131
1.821ProAsn: 1.821 ± 1.119
4.554ProPro: 4.554 ± 1.547
0.0ProGln: 0.0 ± 0.0
5.464ProArg: 5.464 ± 0.857
4.554ProSer: 4.554 ± 1.547
2.732ProThr: 2.732 ± 0.821
2.732ProVal: 2.732 ± 1.678
0.911ProTrp: 0.911 ± 0.69
2.732ProTyr: 2.732 ± 0.428
0.0ProXaa: 0.0 ± 0.0
Gln
5.464GlnAla: 5.464 ± 2.107
0.911GlnCys: 0.911 ± 0.559
2.732GlnAsp: 2.732 ± 0.428
1.821GlnGlu: 1.821 ± 0.131
0.911GlnPhe: 0.911 ± 0.69
1.821GlnGly: 1.821 ± 0.131
0.0GlnHis: 0.0 ± 0.0
0.0GlnIle: 0.0 ± 0.0
1.821GlnLys: 1.821 ± 0.131
2.732GlnLeu: 2.732 ± 1.678
0.0GlnMet: 0.0 ± 0.0
1.821GlnAsn: 1.821 ± 0.131
0.911GlnPro: 0.911 ± 0.559
0.0GlnGln: 0.0 ± 0.0
3.643GlnArg: 3.643 ± 1.511
4.554GlnSer: 4.554 ± 0.298
0.0GlnThr: 0.0 ± 0.0
2.732GlnVal: 2.732 ± 0.428
0.0GlnTrp: 0.0 ± 0.0
5.464GlnTyr: 5.464 ± 0.393
0.0GlnXaa: 0.0 ± 0.0
Arg
3.643ArgAla: 3.643 ± 0.262
0.0ArgCys: 0.0 ± 0.0
0.911ArgAsp: 0.911 ± 0.69
1.821ArgGlu: 1.821 ± 0.131
2.732ArgPhe: 2.732 ± 0.821
0.911ArgGly: 0.911 ± 0.559
0.911ArgHis: 0.911 ± 0.559
1.821ArgIle: 1.821 ± 0.131
7.286ArgLys: 7.286 ± 3.023
2.732ArgLeu: 2.732 ± 1.678
0.0ArgMet: 0.0 ± 0.0
4.554ArgAsn: 4.554 ± 0.298
4.554ArgPro: 4.554 ± 1.547
0.911ArgGln: 0.911 ± 0.559
5.464ArgArg: 5.464 ± 0.857
2.732ArgSer: 2.732 ± 0.428
4.554ArgThr: 4.554 ± 2.202
1.821ArgVal: 1.821 ± 0.131
0.0ArgTrp: 0.0 ± 0.0
3.643ArgTyr: 3.643 ± 0.988
0.0ArgXaa: 0.0 ± 0.0
Ser
1.821SerAla: 1.821 ± 1.381
1.821SerCys: 1.821 ± 1.119
9.107SerAsp: 9.107 ± 0.595
2.732SerGlu: 2.732 ± 0.821
4.554SerPhe: 4.554 ± 1.547
11.84SerGly: 11.84 ± 0.226
0.911SerHis: 0.911 ± 0.559
4.554SerIle: 4.554 ± 0.952
4.554SerLys: 4.554 ± 0.952
8.197SerLeu: 8.197 ± 1.214
0.0SerMet: 0.0 ± 0.0
6.375SerAsn: 6.375 ± 0.167
5.464SerPro: 5.464 ± 0.857
1.821SerGln: 1.821 ± 0.131
2.732SerArg: 2.732 ± 0.428
7.286SerSer: 7.286 ± 0.524
5.464SerThr: 5.464 ± 0.393
7.286SerVal: 7.286 ± 0.524
0.0SerTrp: 0.0 ± 0.0
3.643SerTyr: 3.643 ± 0.262
0.0SerXaa: 0.0 ± 0.0
Thr
1.821ThrAla: 1.821 ± 1.119
0.0ThrCys: 0.0 ± 0.0
2.732ThrAsp: 2.732 ± 0.821
1.821ThrGlu: 1.821 ± 0.131
2.732ThrPhe: 2.732 ± 0.428
3.643ThrGly: 3.643 ± 2.237
0.0ThrHis: 0.0 ± 0.0
3.643ThrIle: 3.643 ± 0.262
4.554ThrLys: 4.554 ± 0.298
3.643ThrLeu: 3.643 ± 2.761
1.821ThrMet: 1.821 ± 0.131
6.375ThrAsn: 6.375 ± 1.416
2.732ThrPro: 2.732 ± 0.821
3.643ThrGln: 3.643 ± 0.262
4.554ThrArg: 4.554 ± 0.952
5.464ThrSer: 5.464 ± 2.107
2.732ThrThr: 2.732 ± 0.428
2.732ThrVal: 2.732 ± 2.071
0.0ThrTrp: 0.0 ± 0.0
3.643ThrTyr: 3.643 ± 0.988
0.0ThrXaa: 0.0 ± 0.0
Val
3.643ValAla: 3.643 ± 1.511
0.0ValCys: 0.0 ± 0.0
2.732ValAsp: 2.732 ± 0.428
1.821ValGlu: 1.821 ± 0.131
0.0ValPhe: 0.0 ± 0.0
5.464ValGly: 5.464 ± 3.356
0.911ValHis: 0.911 ± 0.559
0.911ValIle: 0.911 ± 0.559
7.286ValLys: 7.286 ± 3.023
2.732ValLeu: 2.732 ± 0.821
0.911ValMet: 0.911 ± 0.69
4.554ValAsn: 4.554 ± 0.298
4.554ValPro: 4.554 ± 0.298
3.643ValGln: 3.643 ± 2.237
1.821ValArg: 1.821 ± 1.119
7.286ValSer: 7.286 ± 1.773
2.732ValThr: 2.732 ± 0.821
4.554ValVal: 4.554 ± 0.952
0.911ValTrp: 0.911 ± 0.69
2.732ValTyr: 2.732 ± 0.428
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.911TrpAsp: 0.911 ± 0.69
0.0TrpGlu: 0.0 ± 0.0
1.821TrpPhe: 1.821 ± 1.119
1.821TrpGly: 1.821 ± 1.381
0.911TrpHis: 0.911 ± 0.559
0.911TrpIle: 0.911 ± 0.559
0.0TrpLys: 0.0 ± 0.0
0.911TrpLeu: 0.911 ± 0.559
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.911TrpPro: 0.911 ± 0.559
0.0TrpGln: 0.0 ± 0.0
0.911TrpArg: 0.911 ± 0.69
0.0TrpSer: 0.0 ± 0.0
0.911TrpThr: 0.911 ± 0.559
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.911TyrAla: 0.911 ± 0.559
0.0TyrCys: 0.0 ± 0.0
2.732TyrAsp: 2.732 ± 0.428
2.732TyrGlu: 2.732 ± 0.821
3.643TyrPhe: 3.643 ± 2.761
2.732TyrGly: 2.732 ± 0.428
1.821TyrHis: 1.821 ± 1.381
3.643TyrIle: 3.643 ± 0.988
3.643TyrLys: 3.643 ± 0.988
5.464TyrLeu: 5.464 ± 2.892
1.821TyrMet: 1.821 ± 0.131
2.732TyrAsn: 2.732 ± 0.428
1.821TyrPro: 1.821 ± 1.381
4.554TyrGln: 4.554 ± 0.298
2.732TyrArg: 2.732 ± 0.821
3.643TyrSer: 3.643 ± 0.262
4.554TyrThr: 4.554 ± 0.298
2.732TyrVal: 2.732 ± 0.821
0.911TyrTrp: 0.911 ± 0.559
4.554TyrTyr: 4.554 ± 0.298
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1099 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski