Amino acid dipepetide frequency for Gracilariopsis chorda

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.381AlaAla: 9.381 ± 0.076	1.335AlaCys: 1.335 ± 0.021	4.233AlaAsp: 4.233 ± 0.035	5.124AlaGlu: 5.124 ± 0.042	3.359AlaPhe: 3.359 ± 0.029	4.65AlaGly: 4.65 ± 0.042	2.21AlaHis: 2.21 ± 0.026	4.078AlaIle: 4.078 ± 0.033	4.119AlaLys: 4.119 ± 0.035	8.872AlaLeu: 8.872 ± 0.066	2.07AlaMet: 2.07 ± 0.023	2.922AlaAsn: 2.922 ± 0.031	4.529AlaPro: 4.529 ± 0.05	3.313AlaGln: 3.313 ± 0.032	5.589AlaArg: 5.589 ± 0.042	7.184AlaSer: 7.184 ± 0.053	4.864AlaThr: 4.864 ± 0.036	6.508AlaVal: 6.508 ± 0.049	0.839AlaTrp: 0.839 ± 0.016	1.946AlaTyr: 1.946 ± 0.025	0.0AlaXaa: 0.0 ± 0.0
Cys	1.419CysAla: 1.419 ± 0.022	0.304CysCys: 0.304 ± 0.01	0.934CysAsp: 0.934 ± 0.018	0.957CysGlu: 0.957 ± 0.017	0.703CysPhe: 0.703 ± 0.013	1.163CysGly: 1.163 ± 0.017	0.383CysHis: 0.383 ± 0.01	0.814CysIle: 0.814 ± 0.016	0.676CysLys: 0.676 ± 0.017	1.336CysLeu: 1.336 ± 0.02	0.371CysMet: 0.371 ± 0.009	0.592CysAsn: 0.592 ± 0.013	0.773CysPro: 0.773 ± 0.019	0.467CysGln: 0.467 ± 0.012	1.064CysArg: 1.064 ± 0.017	1.338CysSer: 1.338 ± 0.021	0.968CysThr: 0.968 ± 0.018	1.268CysVal: 1.268 ± 0.018	0.177CysTrp: 0.177 ± 0.009	0.416CysTyr: 0.416 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	5.026AspAla: 5.026 ± 0.038	0.765AspCys: 0.765 ± 0.014	3.955AspAsp: 3.955 ± 0.046	4.263AspGlu: 4.263 ± 0.045	2.034AspPhe: 2.034 ± 0.021	4.047AspGly: 4.047 ± 0.039	1.315AspHis: 1.315 ± 0.021	2.932AspIle: 2.932 ± 0.03	2.308AspLys: 2.308 ± 0.025	4.584AspLeu: 4.584 ± 0.033	1.392AspMet: 1.392 ± 0.016	1.898AspAsn: 1.898 ± 0.022	2.647AspPro: 2.647 ± 0.03	1.643AspGln: 1.643 ± 0.02	3.161AspArg: 3.161 ± 0.033	4.076AspSer: 4.076 ± 0.038	2.791AspThr: 2.791 ± 0.027	4.511AspVal: 4.511 ± 0.033	0.627AspTrp: 0.627 ± 0.014	1.343AspTyr: 1.343 ± 0.021	0.0AspXaa: 0.0 ± 0.0
Glu	5.213GluAla: 5.213 ± 0.046	0.95GluCys: 0.95 ± 0.018	3.776GluAsp: 3.776 ± 0.034	5.233GluGlu: 5.233 ± 0.065	1.886GluPhe: 1.886 ± 0.024	3.407GluGly: 3.407 ± 0.036	1.677GluHis: 1.677 ± 0.023	2.679GluIle: 2.679 ± 0.029	3.719GluLys: 3.719 ± 0.039	5.52GluLeu: 5.52 ± 0.043	1.546GluMet: 1.546 ± 0.022	2.662GluAsn: 2.662 ± 0.027	2.429GluPro: 2.429 ± 0.031	2.805GluGln: 2.805 ± 0.031	4.708GluArg: 4.708 ± 0.042	4.433GluSer: 4.433 ± 0.045	3.267GluThr: 3.267 ± 0.033	3.878GluVal: 3.878 ± 0.034	0.741GluTrp: 0.741 ± 0.013	1.565GluTyr: 1.565 ± 0.021	0.0GluXaa: 0.0 ± 0.0
Phe	3.135PheAla: 3.135 ± 0.03	0.717PheCys: 0.717 ± 0.015	2.331PheAsp: 2.331 ± 0.029	2.398PheGlu: 2.398 ± 0.028	1.58PhePhe: 1.58 ± 0.025	2.534PheGly: 2.534 ± 0.03	0.923PheHis: 0.923 ± 0.014	1.711PheIle: 1.711 ± 0.025	1.506PheLys: 1.506 ± 0.021	3.446PheLeu: 3.446 ± 0.036	0.812PheMet: 0.812 ± 0.014	1.309PheAsn: 1.309 ± 0.019	1.757PhePro: 1.757 ± 0.022	1.217PheGln: 1.217 ± 0.02	2.379PheArg: 2.379 ± 0.024	3.145PheSer: 3.145 ± 0.026	1.967PheThr: 1.967 ± 0.024	2.999PheVal: 2.999 ± 0.03	0.46PheTrp: 0.46 ± 0.01	0.985PheTyr: 0.985 ± 0.019	0.0PheXaa: 0.0 ± 0.0
Gly	4.879GlyAla: 4.879 ± 0.046	0.949GlyCys: 0.949 ± 0.017	3.495GlyAsp: 3.495 ± 0.033	3.538GlyGlu: 3.538 ± 0.037	2.411GlyPhe: 2.411 ± 0.029	4.628GlyGly: 4.628 ± 0.06	1.469GlyHis: 1.469 ± 0.022	3.078GlyIle: 3.078 ± 0.029	3.246GlyLys: 3.246 ± 0.033	4.953GlyLeu: 4.953 ± 0.044	1.549GlyMet: 1.549 ± 0.025	2.404GlyAsn: 2.404 ± 0.026	2.203GlyPro: 2.203 ± 0.028	1.845GlyGln: 1.845 ± 0.023	4.16GlyArg: 4.16 ± 0.038	4.948GlySer: 4.948 ± 0.043	3.529GlyThr: 3.529 ± 0.028	4.486GlyVal: 4.486 ± 0.039	0.723GlyTrp: 0.723 ± 0.014	1.629GlyTyr: 1.629 ± 0.024	0.0GlyXaa: 0.0 ± 0.0
His	2.333HisAla: 2.333 ± 0.033	0.479HisCys: 0.479 ± 0.011	1.394HisAsp: 1.394 ± 0.019	1.379HisGlu: 1.379 ± 0.02	1.071HisPhe: 1.071 ± 0.019	1.701HisGly: 1.701 ± 0.019	0.958HisHis: 0.958 ± 0.02	1.329HisIle: 1.329 ± 0.019	0.973HisLys: 0.973 ± 0.016	2.376HisLeu: 2.376 ± 0.025	0.585HisMet: 0.585 ± 0.011	0.995HisAsn: 0.995 ± 0.018	1.736HisPro: 1.736 ± 0.024	0.974HisGln: 0.974 ± 0.019	1.814HisArg: 1.814 ± 0.023	2.256HisSer: 2.256 ± 0.027	1.469HisThr: 1.469 ± 0.02	1.949HisVal: 1.949 ± 0.025	0.268HisTrp: 0.268 ± 0.009	0.615HisTyr: 0.615 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	4.269IleAla: 4.269 ± 0.035	0.848IleCys: 0.848 ± 0.018	2.792IleAsp: 2.792 ± 0.026	2.852IleGlu: 2.852 ± 0.026	1.53IlePhe: 1.53 ± 0.023	2.813IleGly: 2.813 ± 0.029	1.158IleHis: 1.158 ± 0.016	2.072IleIle: 2.072 ± 0.027	1.767IleLys: 1.767 ± 0.021	4.01IleLeu: 4.01 ± 0.039	0.98IleMet: 0.98 ± 0.015	1.508IleAsn: 1.508 ± 0.019	2.723IlePro: 2.723 ± 0.027	1.625IleGln: 1.625 ± 0.021	3.202IleArg: 3.202 ± 0.033	3.976IleSer: 3.976 ± 0.029	2.589IleThr: 2.589 ± 0.023	3.522IleVal: 3.522 ± 0.032	0.478IleTrp: 0.478 ± 0.013	1.008IleTyr: 1.008 ± 0.018	0.0IleXaa: 0.0 ± 0.0
Lys	3.935LysAla: 3.935 ± 0.034	0.781LysCys: 0.781 ± 0.024	2.448LysAsp: 2.448 ± 0.027	3.363LysGlu: 3.363 ± 0.04	1.383LysPhe: 1.383 ± 0.018	2.708LysGly: 2.708 ± 0.024	1.333LysHis: 1.333 ± 0.02	1.912LysIle: 1.912 ± 0.021	3.352LysLys: 3.352 ± 0.048	4.362LysLeu: 4.362 ± 0.036	1.095LysMet: 1.095 ± 0.018	1.859LysAsn: 1.859 ± 0.023	2.541LysPro: 2.541 ± 0.03	2.136LysGln: 2.136 ± 0.026	4.286LysArg: 4.286 ± 0.043	3.658LysSer: 3.658 ± 0.036	2.657LysThr: 2.657 ± 0.03	2.9LysVal: 2.9 ± 0.027	0.576LysTrp: 0.576 ± 0.01	1.289LysTyr: 1.289 ± 0.021	0.0LysXaa: 0.0 ± 0.0
Leu	7.504LeuAla: 7.504 ± 0.055	1.673LeuCys: 1.673 ± 0.024	4.741LeuAsp: 4.741 ± 0.04	5.348LeuGlu: 5.348 ± 0.048	3.654LeuPhe: 3.654 ± 0.039	4.971LeuGly: 4.971 ± 0.044	2.71LeuHis: 2.71 ± 0.031	3.735LeuIle: 3.735 ± 0.035	4.314LeuLys: 4.314 ± 0.037	9.032LeuLeu: 9.032 ± 0.069	1.837LeuMet: 1.837 ± 0.022	3.256LeuAsn: 3.256 ± 0.031	5.266LeuPro: 5.266 ± 0.043	4.057LeuGln: 4.057 ± 0.039	7.278LeuArg: 7.278 ± 0.054	7.991LeuSer: 7.991 ± 0.047	4.613LeuThr: 4.613 ± 0.036	5.828LeuVal: 5.828 ± 0.044	0.987LeuTrp: 0.987 ± 0.016	2.282LeuTyr: 2.282 ± 0.027	0.0LeuXaa: 0.0 ± 0.0
Met	1.978MetAla: 1.978 ± 0.023	0.358MetCys: 0.358 ± 0.008	1.237MetAsp: 1.237 ± 0.018	1.462MetGlu: 1.462 ± 0.016	0.844MetPhe: 0.844 ± 0.015	1.282MetGly: 1.282 ± 0.022	0.649MetHis: 0.649 ± 0.011	0.928MetIle: 0.928 ± 0.015	1.315MetLys: 1.315 ± 0.017	2.151MetLeu: 2.151 ± 0.026	0.577MetMet: 0.577 ± 0.014	0.942MetAsn: 0.942 ± 0.016	1.202MetPro: 1.202 ± 0.021	0.97MetGln: 0.97 ± 0.016	1.615MetArg: 1.615 ± 0.02	1.88MetSer: 1.88 ± 0.021	1.215MetThr: 1.215 ± 0.018	1.361MetVal: 1.361 ± 0.018	0.25MetTrp: 0.25 ± 0.007	0.603MetTyr: 0.603 ± 0.012	0.0MetXaa: 0.0 ± 0.0
Asn	3.564AsnAla: 3.564 ± 0.034	0.583AsnCys: 0.583 ± 0.012	2.159AsnAsp: 2.159 ± 0.024	2.34AsnGlu: 2.34 ± 0.024	1.247AsnPhe: 1.247 ± 0.018	2.815AsnGly: 2.815 ± 0.028	0.903AsnHis: 0.903 ± 0.014	1.869AsnIle: 1.869 ± 0.021	1.58AsnLys: 1.58 ± 0.025	3.131AsnLeu: 3.131 ± 0.031	0.931AsnMet: 0.931 ± 0.016	1.471AsnAsn: 1.471 ± 0.024	2.205AsnPro: 2.205 ± 0.025	1.236AsnGln: 1.236 ± 0.021	2.376AsnArg: 2.376 ± 0.026	2.952AsnSer: 2.952 ± 0.027	2.094AsnThr: 2.094 ± 0.027	2.855AsnVal: 2.855 ± 0.031	0.396AsnTrp: 0.396 ± 0.01	0.878AsnTyr: 0.878 ± 0.017	0.0AsnXaa: 0.0 ± 0.0
Pro	4.218ProAla: 4.218 ± 0.046	0.677ProCys: 0.677 ± 0.018	2.764ProAsp: 2.764 ± 0.029	2.948ProGlu: 2.948 ± 0.036	2.06ProPhe: 2.06 ± 0.028	2.791ProGly: 2.791 ± 0.037	1.582ProHis: 1.582 ± 0.023	2.183ProIle: 2.183 ± 0.021	2.285ProLys: 2.285 ± 0.025	4.652ProLeu: 4.652 ± 0.043	0.961ProMet: 0.961 ± 0.016	2.147ProAsn: 2.147 ± 0.027	4.892ProPro: 4.892 ± 0.08	2.26ProGln: 2.26 ± 0.03	3.455ProArg: 3.455 ± 0.036	5.807ProSer: 5.807 ± 0.056	3.406ProThr: 3.406 ± 0.039	3.493ProVal: 3.493 ± 0.032	0.517ProTrp: 0.517 ± 0.012	1.285ProTyr: 1.285 ± 0.021	0.0ProXaa: 0.0 ± 0.0
Gln	2.949GlnAla: 2.949 ± 0.025	0.571GlnCys: 0.571 ± 0.013	1.697GlnAsp: 1.697 ± 0.019	2.072GlnGlu: 2.072 ± 0.022	1.315GlnPhe: 1.315 ± 0.019	1.834GlnGly: 1.834 ± 0.026	1.208GlnHis: 1.208 ± 0.022	1.726GlnIle: 1.726 ± 0.02	1.974GlnLys: 1.974 ± 0.026	3.851GlnLeu: 3.851 ± 0.036	0.922GlnMet: 0.922 ± 0.016	1.591GlnAsn: 1.591 ± 0.023	2.377GlnPro: 2.377 ± 0.037	2.388GlnGln: 2.388 ± 0.054	3.009GlnArg: 3.009 ± 0.03	3.172GlnSer: 3.172 ± 0.03	2.209GlnThr: 2.209 ± 0.024	2.342GlnVal: 2.342 ± 0.025	0.451GlnTrp: 0.451 ± 0.01	0.94GlnTyr: 0.94 ± 0.016	0.0GlnXaa: 0.0 ± 0.0
Arg	5.952ArgAla: 5.952 ± 0.048	1.082ArgCys: 1.082 ± 0.016	3.574ArgAsp: 3.574 ± 0.032	4.21ArgGlu: 4.21 ± 0.041	2.76ArgPhe: 2.76 ± 0.027	3.892ArgGly: 3.892 ± 0.038	1.831ArgHis: 1.831 ± 0.023	3.442ArgIle: 3.442 ± 0.034	4.127ArgLys: 4.127 ± 0.042	6.335ArgLeu: 6.335 ± 0.042	1.747ArgMet: 1.747 ± 0.017	2.896ArgAsn: 2.896 ± 0.026	3.373ArgPro: 3.373 ± 0.038	2.589ArgGln: 2.589 ± 0.026	6.326ArgArg: 6.326 ± 0.064	5.627ArgSer: 5.627 ± 0.043	3.793ArgThr: 3.793 ± 0.03	4.525ArgVal: 4.525 ± 0.035	0.756ArgTrp: 0.756 ± 0.013	1.833ArgTyr: 1.833 ± 0.022	0.0ArgXaa: 0.0 ± 0.0
Ser	7.417SerAla: 7.417 ± 0.055	1.249SerCys: 1.249 ± 0.02	4.604SerAsp: 4.604 ± 0.04	4.915SerGlu: 4.915 ± 0.045	3.266SerPhe: 3.266 ± 0.032	5.161SerGly: 5.161 ± 0.04	2.132SerHis: 2.132 ± 0.026	3.723SerIle: 3.723 ± 0.031	3.912SerLys: 3.912 ± 0.034	7.345SerLeu: 7.345 ± 0.051	1.833SerMet: 1.833 ± 0.022	3.204SerAsn: 3.204 ± 0.029	4.728SerPro: 4.728 ± 0.053	3.158SerGln: 3.158 ± 0.034	5.518SerArg: 5.518 ± 0.045	8.86SerSer: 8.86 ± 0.082	5.204SerThr: 5.204 ± 0.034	5.684SerVal: 5.684 ± 0.045	0.791SerTrp: 0.791 ± 0.015	1.838SerTyr: 1.838 ± 0.022	0.0SerXaa: 0.0 ± 0.0
Thr	5.218ThrAla: 5.218 ± 0.039	0.899ThrCys: 0.899 ± 0.018	2.943ThrAsp: 2.943 ± 0.023	3.232ThrGlu: 3.232 ± 0.034	2.051ThrPhe: 2.051 ± 0.026	3.404ThrGly: 3.404 ± 0.029	1.379ThrHis: 1.379 ± 0.019	2.641ThrIle: 2.641 ± 0.025	2.502ThrLys: 2.502 ± 0.028	5.025ThrLeu: 5.025 ± 0.038	1.162ThrMet: 1.162 ± 0.015	2.045ThrAsn: 2.045 ± 0.025	3.77ThrPro: 3.77 ± 0.047	1.904ThrGln: 1.904 ± 0.021	3.428ThrArg: 3.428 ± 0.029	4.892ThrSer: 4.892 ± 0.04	3.583ThrThr: 3.583 ± 0.04	4.026ThrVal: 4.026 ± 0.033	0.55ThrTrp: 0.55 ± 0.014	1.275ThrTyr: 1.275 ± 0.021	0.0ThrXaa: 0.0 ± 0.0
Val	5.946ValAla: 5.946 ± 0.044	1.234ValCys: 1.234 ± 0.023	3.993ValAsp: 3.993 ± 0.034	4.24ValGlu: 4.24 ± 0.037	2.726ValPhe: 2.726 ± 0.031	3.999ValGly: 3.999 ± 0.038	1.874ValHis: 1.874 ± 0.024	3.117ValIle: 3.117 ± 0.029	3.118ValLys: 3.118 ± 0.025	6.906ValLeu: 6.906 ± 0.045	1.551ValMet: 1.551 ± 0.019	2.39ValAsn: 2.39 ± 0.028	3.727ValPro: 3.727 ± 0.035	2.81ValGln: 2.81 ± 0.028	4.793ValArg: 4.793 ± 0.032	5.725ValSer: 5.725 ± 0.044	3.778ValThr: 3.778 ± 0.033	5.206ValVal: 5.206 ± 0.048	0.858ValTrp: 0.858 ± 0.015	1.807ValTyr: 1.807 ± 0.024	0.0ValXaa: 0.0 ± 0.0
Trp	0.776TrpAla: 0.776 ± 0.015	0.199TrpCys: 0.199 ± 0.008	0.68TrpAsp: 0.68 ± 0.015	0.604TrpGlu: 0.604 ± 0.013	0.455TrpPhe: 0.455 ± 0.013	0.588TrpGly: 0.588 ± 0.012	0.302TrpHis: 0.302 ± 0.008	0.545TrpIle: 0.545 ± 0.012	0.682TrpLys: 0.682 ± 0.013	1.006TrpLeu: 1.006 ± 0.018	0.321TrpMet: 0.321 ± 0.009	0.529TrpAsn: 0.529 ± 0.014	0.385TrpPro: 0.385 ± 0.01	0.39TrpGln: 0.39 ± 0.01	0.857TrpArg: 0.857 ± 0.015	0.802TrpSer: 0.802 ± 0.013	0.63TrpThr: 0.63 ± 0.015	0.665TrpVal: 0.665 ± 0.013	0.169TrpTrp: 0.169 ± 0.007	0.337TrpTyr: 0.337 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.01TyrAla: 2.01 ± 0.024	0.47TyrCys: 0.47 ± 0.011	1.566TyrAsp: 1.566 ± 0.022	1.616TyrGlu: 1.616 ± 0.023	0.977TyrPhe: 0.977 ± 0.018	1.734TyrGly: 1.734 ± 0.023	0.66TyrHis: 0.66 ± 0.014	1.208TyrIle: 1.208 ± 0.018	1.101TyrLys: 1.101 ± 0.016	2.186TyrLeu: 2.186 ± 0.027	0.575TyrMet: 0.575 ± 0.013	0.965TyrAsn: 0.965 ± 0.018	1.123TyrPro: 1.123 ± 0.017	0.811TyrGln: 0.811 ± 0.015	1.652TyrArg: 1.652 ± 0.021	1.819TyrSer: 1.819 ± 0.022	1.303TyrThr: 1.303 ± 0.019	1.793TyrVal: 1.793 ± 0.022	0.305TyrTrp: 0.305 ± 0.011	0.768TyrTyr: 0.768 ± 0.016	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 10593 proteins (4111427 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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