Amino acid dipepetide frequency for Tetraselmis viridis virus S20

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.842AlaAla: 9.842 ± 1.588
0.72AlaCys: 0.72 ± 0.231
6.641AlaAsp: 6.641 ± 0.863
5.441AlaGlu: 5.441 ± 0.666
2.8AlaPhe: 2.8 ± 0.394
9.121AlaGly: 9.121 ± 0.746
2.64AlaHis: 2.64 ± 0.476
5.681AlaIle: 5.681 ± 0.524
3.281AlaLys: 3.281 ± 0.949
8.881AlaLeu: 8.881 ± 0.853
3.04AlaMet: 3.04 ± 0.52
3.441AlaAsn: 3.441 ± 0.524
4.721AlaPro: 4.721 ± 0.753
5.041AlaGln: 5.041 ± 0.836
7.921AlaArg: 7.921 ± 0.894
6.081AlaSer: 6.081 ± 0.66
4.881AlaThr: 4.881 ± 0.78
6.401AlaVal: 6.401 ± 0.944
2.4AlaTrp: 2.4 ± 0.55
2.24AlaTyr: 2.24 ± 0.461
0.0AlaXaa: 0.0 ± 0.0
Cys
0.88CysAla: 0.88 ± 0.288
0.16CysCys: 0.16 ± 0.119
0.72CysAsp: 0.72 ± 0.232
0.48CysGlu: 0.48 ± 0.18
0.32CysPhe: 0.32 ± 0.144
0.72CysGly: 0.72 ± 0.256
0.24CysHis: 0.24 ± 0.135
0.48CysIle: 0.48 ± 0.199
0.24CysLys: 0.24 ± 0.168
0.88CysLeu: 0.88 ± 0.259
0.4CysMet: 0.4 ± 0.154
0.0CysAsn: 0.0 ± 0.0
0.56CysPro: 0.56 ± 0.212
0.4CysGln: 0.4 ± 0.182
0.96CysArg: 0.96 ± 0.289
0.32CysSer: 0.32 ± 0.146
0.4CysThr: 0.4 ± 0.193
0.8CysVal: 0.8 ± 0.25
0.4CysTrp: 0.4 ± 0.161
0.48CysTyr: 0.48 ± 0.175
0.0CysXaa: 0.0 ± 0.0
Asp
6.321AspAla: 6.321 ± 0.635
0.4AspCys: 0.4 ± 0.173
5.521AspAsp: 5.521 ± 0.564
4.961AspGlu: 4.961 ± 0.799
2.16AspPhe: 2.16 ± 0.378
5.681AspGly: 5.681 ± 0.767
2.0AspHis: 2.0 ± 0.461
2.88AspIle: 2.88 ± 0.549
1.6AspLys: 1.6 ± 0.3
6.161AspLeu: 6.161 ± 0.584
2.08AspMet: 2.08 ± 0.497
1.68AspAsn: 1.68 ± 0.416
4.321AspPro: 4.321 ± 0.605
2.8AspGln: 2.8 ± 0.385
4.481AspArg: 4.481 ± 0.462
2.88AspSer: 2.88 ± 0.477
4.161AspThr: 4.161 ± 0.547
3.681AspVal: 3.681 ± 0.448
1.36AspTrp: 1.36 ± 0.384
1.76AspTyr: 1.76 ± 0.311
0.0AspXaa: 0.0 ± 0.0
Glu
8.561GluAla: 8.561 ± 0.869
0.88GluCys: 0.88 ± 0.304
4.721GluAsp: 4.721 ± 0.665
4.561GluGlu: 4.561 ± 0.659
2.48GluPhe: 2.48 ± 0.445
4.641GluGly: 4.641 ± 0.55
1.76GluHis: 1.76 ± 0.384
2.24GluIle: 2.24 ± 0.381
1.36GluLys: 1.36 ± 0.327
6.481GluLeu: 6.481 ± 0.586
2.24GluMet: 2.24 ± 0.436
1.76GluAsn: 1.76 ± 0.439
4.321GluPro: 4.321 ± 1.053
1.84GluGln: 1.84 ± 0.396
4.721GluArg: 4.721 ± 0.619
4.001GluSer: 4.001 ± 0.487
3.281GluThr: 3.281 ± 0.475
4.801GluVal: 4.801 ± 0.748
1.76GluTrp: 1.76 ± 0.329
1.04GluTyr: 1.04 ± 0.238
0.0GluXaa: 0.0 ± 0.0
Phe
2.32PheAla: 2.32 ± 0.365
0.32PheCys: 0.32 ± 0.142
2.4PheAsp: 2.4 ± 0.362
2.24PheGlu: 2.24 ± 0.298
0.64PhePhe: 0.64 ± 0.207
3.441PheGly: 3.441 ± 0.695
0.8PheHis: 0.8 ± 0.258
2.32PheIle: 2.32 ± 0.428
1.28PheLys: 1.28 ± 0.279
3.12PheLeu: 3.12 ± 0.434
1.04PheMet: 1.04 ± 0.311
1.12PheAsn: 1.12 ± 0.448
1.04PhePro: 1.04 ± 0.287
1.28PheGln: 1.28 ± 0.299
1.52PheArg: 1.52 ± 0.365
1.84PheSer: 1.84 ± 0.355
2.24PheThr: 2.24 ± 0.416
1.04PheVal: 1.04 ± 0.34
0.8PheTrp: 0.8 ± 0.276
0.72PheTyr: 0.72 ± 0.246
0.0PheXaa: 0.0 ± 0.0
Gly
8.001GlyAla: 8.001 ± 0.862
0.88GlyCys: 0.88 ± 0.27
6.001GlyAsp: 6.001 ± 0.534
5.601GlyGlu: 5.601 ± 0.762
3.681GlyPhe: 3.681 ± 0.397
6.961GlyGly: 6.961 ± 0.978
1.76GlyHis: 1.76 ± 0.362
4.641GlyIle: 4.641 ± 0.565
3.841GlyLys: 3.841 ± 0.568
7.841GlyLeu: 7.841 ± 0.866
2.08GlyMet: 2.08 ± 0.471
2.48GlyAsn: 2.48 ± 0.39
4.641GlyPro: 4.641 ± 0.534
4.081GlyGln: 4.081 ± 0.454
5.201GlyArg: 5.201 ± 0.586
4.801GlySer: 4.801 ± 0.582
4.881GlyThr: 4.881 ± 0.778
4.801GlyVal: 4.801 ± 0.639
1.76GlyTrp: 1.76 ± 0.347
2.08GlyTyr: 2.08 ± 0.489
0.0GlyXaa: 0.0 ± 0.0
His
1.76HisAla: 1.76 ± 0.39
0.32HisCys: 0.32 ± 0.154
1.28HisAsp: 1.28 ± 0.24
1.2HisGlu: 1.2 ± 0.357
0.72HisPhe: 0.72 ± 0.266
2.0HisGly: 2.0 ± 0.372
0.4HisHis: 0.4 ± 0.169
1.6HisIle: 1.6 ± 0.522
0.8HisLys: 0.8 ± 0.291
1.76HisLeu: 1.76 ± 0.438
0.48HisMet: 0.48 ± 0.199
0.72HisAsn: 0.72 ± 0.237
2.16HisPro: 2.16 ± 0.403
0.88HisGln: 0.88 ± 0.259
1.68HisArg: 1.68 ± 0.445
0.64HisSer: 0.64 ± 0.256
1.04HisThr: 1.04 ± 0.267
1.84HisVal: 1.84 ± 0.446
0.72HisTrp: 0.72 ± 0.283
0.4HisTyr: 0.4 ± 0.197
0.0HisXaa: 0.0 ± 0.0
Ile
3.361IleAla: 3.361 ± 0.43
0.88IleCys: 0.88 ± 0.259
3.761IleAsp: 3.761 ± 0.613
4.481IleGlu: 4.481 ± 0.691
1.36IlePhe: 1.36 ± 0.306
4.001IleGly: 4.001 ± 0.564
1.04IleHis: 1.04 ± 0.38
2.24IleIle: 2.24 ± 0.557
2.24IleLys: 2.24 ± 0.518
4.241IleLeu: 4.241 ± 0.493
0.88IleMet: 0.88 ± 0.311
1.04IleAsn: 1.04 ± 0.324
1.84IlePro: 1.84 ± 0.374
2.72IleGln: 2.72 ± 0.51
3.601IleArg: 3.601 ± 0.529
2.16IleSer: 2.16 ± 0.431
4.081IleThr: 4.081 ± 0.532
2.16IleVal: 2.16 ± 0.347
0.64IleTrp: 0.64 ± 0.217
1.12IleTyr: 1.12 ± 0.299
0.0IleXaa: 0.0 ± 0.0
Lys
4.801LysAla: 4.801 ± 0.864
0.4LysCys: 0.4 ± 0.165
2.0LysAsp: 2.0 ± 0.465
1.52LysGlu: 1.52 ± 0.401
0.8LysPhe: 0.8 ± 0.311
2.96LysGly: 2.96 ± 0.605
0.88LysHis: 0.88 ± 0.263
1.2LysIle: 1.2 ± 0.313
2.48LysLys: 2.48 ± 0.635
3.361LysLeu: 3.361 ± 0.508
1.28LysMet: 1.28 ± 0.321
0.64LysAsn: 0.64 ± 0.228
2.32LysPro: 2.32 ± 0.622
1.2LysGln: 1.2 ± 0.352
4.161LysArg: 4.161 ± 0.694
2.4LysSer: 2.4 ± 0.431
1.44LysThr: 1.44 ± 0.325
2.48LysVal: 2.48 ± 0.473
0.72LysTrp: 0.72 ± 0.231
0.4LysTyr: 0.4 ± 0.178
0.0LysXaa: 0.0 ± 0.0
Leu
9.041LeuAla: 9.041 ± 0.887
0.32LeuCys: 0.32 ± 0.16
6.001LeuAsp: 6.001 ± 0.806
6.561LeuGlu: 6.561 ± 0.65
1.52LeuPhe: 1.52 ± 0.31
7.761LeuGly: 7.761 ± 0.743
0.96LeuHis: 0.96 ± 0.292
3.441LeuIle: 3.441 ± 0.572
4.081LeuLys: 4.081 ± 0.627
4.961LeuLeu: 4.961 ± 0.513
2.32LeuMet: 2.32 ± 0.471
2.08LeuAsn: 2.08 ± 0.35
4.801LeuPro: 4.801 ± 0.589
3.04LeuGln: 3.04 ± 0.488
5.041LeuArg: 5.041 ± 0.643
5.761LeuSer: 5.761 ± 0.682
5.601LeuThr: 5.601 ± 0.943
4.801LeuVal: 4.801 ± 0.461
1.52LeuTrp: 1.52 ± 0.263
2.24LeuTyr: 2.24 ± 0.449
0.0LeuXaa: 0.0 ± 0.0
Met
4.001MetAla: 4.001 ± 0.628
0.16MetCys: 0.16 ± 0.112
1.28MetAsp: 1.28 ± 0.326
1.04MetGlu: 1.04 ± 0.29
0.88MetPhe: 0.88 ± 0.264
1.84MetGly: 1.84 ± 0.398
0.72MetHis: 0.72 ± 0.254
0.32MetIle: 0.32 ± 0.14
1.12MetLys: 1.12 ± 0.342
2.08MetLeu: 2.08 ± 0.433
0.88MetMet: 0.88 ± 0.227
0.96MetAsn: 0.96 ± 0.24
0.96MetPro: 0.96 ± 0.215
0.96MetGln: 0.96 ± 0.249
2.0MetArg: 2.0 ± 0.454
2.4MetSer: 2.4 ± 0.365
3.201MetThr: 3.201 ± 0.378
1.68MetVal: 1.68 ± 0.331
0.48MetTrp: 0.48 ± 0.195
0.24MetTyr: 0.24 ± 0.137
0.0MetXaa: 0.0 ± 0.0
Asn
3.12AsnAla: 3.12 ± 0.513
0.32AsnCys: 0.32 ± 0.169
1.6AsnAsp: 1.6 ± 0.307
1.68AsnGlu: 1.68 ± 0.293
0.8AsnPhe: 0.8 ± 0.23
3.441AsnGly: 3.441 ± 0.443
0.32AsnHis: 0.32 ± 0.167
0.96AsnIle: 0.96 ± 0.259
0.64AsnLys: 0.64 ± 0.233
2.32AsnLeu: 2.32 ± 0.373
0.48AsnMet: 0.48 ± 0.177
1.04AsnAsn: 1.04 ± 0.311
2.4AsnPro: 2.4 ± 0.561
0.88AsnGln: 0.88 ± 0.237
1.92AsnArg: 1.92 ± 0.389
1.2AsnSer: 1.2 ± 0.311
1.28AsnThr: 1.28 ± 0.32
2.4AsnVal: 2.4 ± 0.54
0.72AsnTrp: 0.72 ± 0.243
0.48AsnTyr: 0.48 ± 0.2
0.0AsnXaa: 0.0 ± 0.0
Pro
5.121ProAla: 5.121 ± 0.734
0.56ProCys: 0.56 ± 0.271
4.481ProAsp: 4.481 ± 0.629
4.641ProGlu: 4.641 ± 1.026
1.52ProPhe: 1.52 ± 0.395
5.441ProGly: 5.441 ± 0.751
1.44ProHis: 1.44 ± 0.273
1.92ProIle: 1.92 ± 0.372
1.6ProLys: 1.6 ± 0.423
4.001ProLeu: 4.001 ± 0.716
1.6ProMet: 1.6 ± 0.364
2.0ProAsn: 2.0 ± 0.392
2.72ProPro: 2.72 ± 0.481
1.44ProGln: 1.44 ± 0.357
3.281ProArg: 3.281 ± 0.602
2.08ProSer: 2.08 ± 0.435
3.04ProThr: 3.04 ± 0.745
3.521ProVal: 3.521 ± 0.54
0.88ProTrp: 0.88 ± 0.267
1.44ProTyr: 1.44 ± 0.341
0.0ProXaa: 0.0 ± 0.0
Gln
5.201GlnAla: 5.201 ± 0.697
0.32GlnCys: 0.32 ± 0.137
2.72GlnAsp: 2.72 ± 0.441
2.48GlnGlu: 2.48 ± 0.425
1.2GlnPhe: 1.2 ± 0.311
3.12GlnGly: 3.12 ± 0.421
0.88GlnHis: 0.88 ± 0.258
1.92GlnIle: 1.92 ± 0.393
1.52GlnLys: 1.52 ± 0.399
3.361GlnLeu: 3.361 ± 0.56
0.8GlnMet: 0.8 ± 0.248
2.08GlnAsn: 2.08 ± 0.393
1.76GlnPro: 1.76 ± 0.388
1.68GlnGln: 1.68 ± 0.427
3.441GlnArg: 3.441 ± 0.57
2.16GlnSer: 2.16 ± 0.458
2.96GlnThr: 2.96 ± 0.567
3.361GlnVal: 3.361 ± 0.514
0.48GlnTrp: 0.48 ± 0.183
0.96GlnTyr: 0.96 ± 0.26
0.0GlnXaa: 0.0 ± 0.0
Arg
8.721ArgAla: 8.721 ± 1.087
1.2ArgCys: 1.2 ± 0.322
5.121ArgAsp: 5.121 ± 0.604
4.801ArgGlu: 4.801 ± 0.693
4.081ArgPhe: 4.081 ± 0.632
5.441ArgGly: 5.441 ± 0.678
1.84ArgHis: 1.84 ± 0.448
3.281ArgIle: 3.281 ± 0.444
3.361ArgLys: 3.361 ± 0.586
5.761ArgLeu: 5.761 ± 0.65
2.16ArgMet: 2.16 ± 0.37
1.92ArgAsn: 1.92 ± 0.434
3.361ArgPro: 3.361 ± 0.461
3.281ArgGln: 3.281 ± 0.483
6.641ArgArg: 6.641 ± 0.804
3.12ArgSer: 3.12 ± 0.442
3.201ArgThr: 3.201 ± 0.523
4.481ArgVal: 4.481 ± 0.636
1.44ArgTrp: 1.44 ± 0.352
1.76ArgTyr: 1.76 ± 0.342
0.0ArgXaa: 0.0 ± 0.0
Ser
4.081SerAla: 4.081 ± 0.645
0.64SerCys: 0.64 ± 0.22
2.8SerAsp: 2.8 ± 0.323
3.521SerGlu: 3.521 ± 0.471
1.6SerPhe: 1.6 ± 0.369
6.641SerGly: 6.641 ± 0.758
1.04SerHis: 1.04 ± 0.252
3.201SerIle: 3.201 ± 0.397
1.6SerLys: 1.6 ± 0.398
3.361SerLeu: 3.361 ± 0.502
1.36SerMet: 1.36 ± 0.307
1.04SerAsn: 1.04 ± 0.329
2.72SerPro: 2.72 ± 0.49
3.281SerGln: 3.281 ± 0.641
4.401SerArg: 4.401 ± 0.419
4.161SerSer: 4.161 ± 0.504
3.841SerThr: 3.841 ± 0.729
4.001SerVal: 4.001 ± 0.535
0.96SerTrp: 0.96 ± 0.231
2.0SerTyr: 2.0 ± 0.41
0.0SerXaa: 0.0 ± 0.0
Thr
5.361ThrAla: 5.361 ± 0.735
0.32ThrCys: 0.32 ± 0.182
3.281ThrAsp: 3.281 ± 0.435
3.681ThrGlu: 3.681 ± 0.505
2.08ThrPhe: 2.08 ± 0.479
5.441ThrGly: 5.441 ± 0.63
1.28ThrHis: 1.28 ± 0.383
3.441ThrIle: 3.441 ± 0.552
2.64ThrLys: 2.64 ± 0.527
4.641ThrLeu: 4.641 ± 0.681
1.44ThrMet: 1.44 ± 0.352
1.36ThrAsn: 1.36 ± 0.291
3.681ThrPro: 3.681 ± 0.577
2.16ThrGln: 2.16 ± 0.396
4.561ThrArg: 4.561 ± 0.622
3.841ThrSer: 3.841 ± 0.543
2.8ThrThr: 2.8 ± 0.534
4.241ThrVal: 4.241 ± 0.837
1.6ThrTrp: 1.6 ± 0.336
1.36ThrTyr: 1.36 ± 0.402
0.0ThrXaa: 0.0 ± 0.0
Val
6.001ValAla: 6.001 ± 0.839
0.72ValCys: 0.72 ± 0.204
3.521ValAsp: 3.521 ± 0.529
4.801ValGlu: 4.801 ± 0.471
1.92ValPhe: 1.92 ± 0.395
4.001ValGly: 4.001 ± 0.579
1.2ValHis: 1.2 ± 0.348
4.241ValIle: 4.241 ± 0.566
2.64ValLys: 2.64 ± 0.51
4.721ValLeu: 4.721 ± 0.532
1.68ValMet: 1.68 ± 0.417
1.6ValAsn: 1.6 ± 0.334
2.64ValPro: 2.64 ± 0.432
3.12ValGln: 3.12 ± 0.539
4.641ValArg: 4.641 ± 0.572
3.921ValSer: 3.921 ± 0.709
4.081ValThr: 4.081 ± 0.685
4.321ValVal: 4.321 ± 0.875
1.6ValTrp: 1.6 ± 0.34
1.28ValTyr: 1.28 ± 0.342
0.0ValXaa: 0.0 ± 0.0
Trp
2.24TrpAla: 2.24 ± 0.392
0.16TrpCys: 0.16 ± 0.104
1.84TrpAsp: 1.84 ± 0.407
1.6TrpGlu: 1.6 ± 0.318
0.32TrpPhe: 0.32 ± 0.155
1.6TrpGly: 1.6 ± 0.407
0.64TrpHis: 0.64 ± 0.241
0.88TrpIle: 0.88 ± 0.275
0.64TrpLys: 0.64 ± 0.221
2.24TrpLeu: 2.24 ± 0.448
0.56TrpMet: 0.56 ± 0.213
0.48TrpAsn: 0.48 ± 0.168
0.48TrpPro: 0.48 ± 0.169
0.56TrpGln: 0.56 ± 0.182
2.32TrpArg: 2.32 ± 0.407
0.96TrpSer: 0.96 ± 0.24
1.6TrpThr: 1.6 ± 0.378
1.2TrpVal: 1.2 ± 0.412
0.56TrpTrp: 0.56 ± 0.219
0.24TrpTyr: 0.24 ± 0.132
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.48TyrAla: 2.48 ± 0.376
0.16TyrCys: 0.16 ± 0.128
1.2TyrAsp: 1.2 ± 0.29
2.16TyrGlu: 2.16 ± 0.367
0.64TyrPhe: 0.64 ± 0.19
1.76TyrGly: 1.76 ± 0.412
0.56TyrHis: 0.56 ± 0.195
0.96TyrIle: 0.96 ± 0.25
0.48TyrLys: 0.48 ± 0.187
1.68TyrLeu: 1.68 ± 0.415
0.32TyrMet: 0.32 ± 0.162
0.56TyrAsn: 0.56 ± 0.187
1.28TyrPro: 1.28 ± 0.305
1.76TyrGln: 1.76 ± 0.401
2.56TyrArg: 2.56 ± 0.531
1.52TyrSer: 1.52 ± 0.317
1.2TyrThr: 1.2 ± 0.342
0.64TyrVal: 0.64 ± 0.194
0.32TyrTrp: 0.32 ± 0.165
0.72TyrTyr: 0.72 ± 0.23
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 55 proteins (12499 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski